DT-Web

DB00279 - Liothyronine


Identification
Name Liothyronine
Accession Number DB00279 (APRD01074)
Type small molecule
Description The L-triiodothyronine (T3, liothyronine) thyroid hormone is normally synthesized and secreted by the thyroid gland in much smaller quantities than L-tetraiodothyronine (T4, levothyroxine, L-thyroxine). Most T3 is derived from peripheral monodeiodination of T4 at the 5 position of the outer ring of the iodothyronine nucleus. The hormone finally delivered and used by the tissues is mainly T3. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 650.9735
Groups approved
Monoisotopic Weight 650.790038137
Pharmacology
Indication Used as replacement or supplemental therapy in patients with hypothyroidism of any etiology, except transient hypothyrodism during the recovery phase of subacute thyroiditis.
Mechanism of action The hormones, T4 and T3, are tyrosine-based hormones produced by the thyroid gland. Iodine is an important component in their synthesis. The major form of thyroid hormone in the blood is thyroxine (T4). This is converted to the more active liothyronine form by deiodinases in peripheral tissues. Liothyronine acts on the body to increase the basal metabolic rate, affect protein synthesis and increase the body's sensitivity to catecholamines (such as adrenaline). The thyroid hormones are essential to proper development and differentiation of all cells of the human body. To various extents T4 and T3 regulate protein, fat and carbohydrate metabolism. Their most pronounced effect is on how human cells use energetic compounds. The thyroid hormone derivatives bind to the thyroid hormone receptors initially to initiate their downstream effects.
Absorption 95% in 4 hours
Protein binding 99.7%
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions
Drug Mechanism of interaction
Calcium Acetate Calcium salts such as calcium acetate may diminish the therapeutic effect of thyroid products such as liothyronine. Separate the doses of the thyroid product and the oral calcium supplement by at least 4 hours. Monitor for decreased therapeutic effects of thyroid products if an oral calcium supplement is initiated/dose increased, or increased effects if an oral calcium supplement is discontinued/dose decreased.
Calcium Chloride Calcium salts such as calcium chloride may diminish the therapeutic effect of thyroid products such as liothyronine. Separate the doses of the thyroid product and the oral calcium supplement by at least 4 hours. Monitor for decreased therapeutic effects of thyroid products if an oral calcium supplement is initiated/dose increased, or increased effects if an oral calcium supplement is discontinued/dose decreased.
Cholestyramine The resin, cholestyramine, decreases the absorption of the thyroid hormones, liothyronine.
Colestipol The resin, colestipol, decreases the absorption of the thyroid hormone, liothyronine.
Digoxin The thyroid hormone, liothyronine, decreases the effect of digoxin.
Warfarin Liothyronine may contribute to the anticoagulant effect of warfarin by increasing the metabolism of vitamin K-dependent clotting factors. Monitor for changes in prothrombin time and anticoagulant effects if liothyronine is initiated, discontinued or dose changed.
Food Interactions Not Available

Targets


Thyroid hormone receptor alpha
Name Thyroid hormone receptor alpha
Gene Name THRA
Pharmacological action yes
Actions agonist
References
  • Jiang W, Miyamoto T, Kakizawa T, Sakuma T, Nishio S, Takeda T, Suzuki S, Hashizume K: Expression of thyroid hormone receptor alpha in 3T3-L1 adipocytes; triiodothyronine increases the expression of lipogenic enzyme and triglyceride accumulation. J Endocrinol. 2004 Aug;182(2):295-302. - Pubmed
  • Kariv R, Enden A, Zvibel I, Rosner G, Brill S, Shafritz DA, Halpern Z, Oren R: Triiodothyronine and interleukin-6 (IL-6) induce expression of HGF in an immortalized rat hepatic stellate cell line. Liver Int. 2003 Jun;23(3):187-93. - Pubmed
  • Mai W, Janier MF, Allioli N, Quignodon L, Chuzel T, Flamant F, Samarut J: Thyroid hormone receptor alpha is a molecular switch of cardiac function between fetal and postnatal life. Proc Natl Acad Sci U S A. 2004 Jul 13;101(28):10332-7. Epub 2004 Jul 6. - Pubmed
  • Sciaudone MP, Yao L, Schaller M, Zinn SA, Freake HC: Diethylenetriaminepentaacetic acid enhances thyroid hormone action by a transcriptional mechanism. Biol Trace Elem Res. 2004 Summer;99(1-3):219-31. - Pubmed
  • Timmer DC, Bakker O, Wiersinga WM: Triiodothyronine affects the alternative splicing of thyroid hormone receptor alpha mRNA. J Endocrinol. 2003 Nov;179(2):217-25. - Pubmed
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
DTHybrid score 0.7358
Thyroid hormone receptor beta-1
Name Thyroid hormone receptor beta-1
Gene Name THRB
Pharmacological action yes
Actions agonist
References
  • Bernal J: Thyroid hormone receptors in brain development and function. Nat Clin Pract Endocrinol Metab. 2007 Mar;3(3):249-59. - Pubmed
  • Gonzalez-Sancho JM, Garcia V, Bonilla F, Munoz A: Thyroid hormone receptors/THR genes in human cancer. Cancer Lett. 2003 Mar 31;192(2):121-32. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Yen PM, Feng X, Flamant F, Chen Y, Walker RL, Weiss RE, Chassande O, Samarut J, Refetoff S, Meltzer PS: Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice. EMBO Rep. 2003 Jun;4(6):581-7. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
  • Wu SY, Sadow PM, Refetoff S, Weiss RE: Tissue responses to thyroid hormone in a kindred with resistance to thyroid hormone harboring a commonly occurring mutation in the thyroid hormone receptor beta gene (P453T). J Lab Clin Med. 2005 Aug;146(2):85-94. - Pubmed
  • Kullak-Ublick GA, Ismair MG, Stieger B, Landmann L, Huber R, Pizzagalli F, Fattinger K, Meier PJ, Hagenbuch B: Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. Gastroenterology. 2001 Feb;120(2):525-33. - Pubmed
  • Kullak-Ublick GA, Ismair MG, Stieger B, Landmann L, Huber R, Pizzagalli F, Fattinger K, Meier PJ, Hagenbuch B: Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. Gastroenterology. 2001 Feb;120(2):525-33. - Pubmed
DTHybrid score 1.4857

Transporters


Solute carrier organic anion transporter family member 1A2
Name Solute carrier organic anion transporter family member 1A2
Gene Name SLCO1A2
Actions substrate
References
  • Fujiwara K, Adachi H, Nishio T, Unno M, Tokui T, Okabe M, Onogawa T, Suzuki T, Asano N, Tanemoto M, Seki M, Shiiba K, Suzuki M, Kondo Y, Nunoki K, Shimosegawa T, Iinuma K, Ito S, Matsuno S, Abe T: Identification of thyroid hormone transporters in humans: different molecules are involved in a tissue-specific manner. Endocrinology. 2001 May;142(5):2005-12. - Pubmed
  • Friesema EC, Docter R, Moerings EP, Stieger B, Hagenbuch B, Meier PJ, Krenning EP, Hennemann G, Visser TJ: Identification of thyroid hormone transporters. Biochem Biophys Res Commun. 1999 Jan 19;254(2):497-501. - Pubmed
  • Kullak-Ublick GA, Ismair MG, Stieger B, Landmann L, Huber R, Pizzagalli F, Fattinger K, Meier PJ, Hagenbuch B: Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. Gastroenterology. 2001 Feb;120(2):525-33. - Pubmed
DTHybrid score 0.5372
Solute carrier organic anion transporter family member 1B1
Name Solute carrier organic anion transporter family member 1B1
Gene Name SLCO1B1
Actions substrate
References
  • Abe T, Kakyo M, Tokui T, Nakagomi R, Nishio T, Nakai D, Nomura H, Unno M, Suzuki M, Naitoh T, Matsuno S, Yawo H: Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1. J Biol Chem. 1999 Jun 11;274(24):17159-63. - Pubmed
  • Kullak-Ublick, G.A. et al. Organic anion-transporting polypeptide B (OATP- B) and its functional comparison with three other OATPs of human liver. Gastroenterology 120, 525-533 (2001). - Pubmed
DTHybrid score 0.6234
Solute carrier organic anion transporter family member 1B3
Name Solute carrier organic anion transporter family member 1B3
Gene Name SLCO1B3
Actions substrate
References
  • Kullak-Ublick GA, Ismair MG, Stieger B, Landmann L, Huber R, Pizzagalli F, Fattinger K, Meier PJ, Hagenbuch B: Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver. Gastroenterology. 2001 Feb;120(2):525-33. - Pubmed
  • Abe T, Unno M, Onogawa T, Tokui T, Kondo TN, Nakagomi R, Adachi H, Fujiwara K, Okabe M, Suzuki T, Nunoki K, Sato E, Kakyo M, Nishio T, Sugita J, Asano N, Tanemoto M, Seki M, Date F, Ono K, Kondo Y, Shiiba K, Suzuki M, Ohtani H, Shimosegawa T, Iinuma K, Nagura H, Ito S, Matsuno S: LST-2, a human liver-specific organic anion transporter, determines methotrexate sensitivity in gastrointestinal cancers. Gastroenterology. 2001 Jun;120(7):1689-99. - Pubmed
DTHybrid score 0.4884
Solute carrier organic anion transporter family member 4C1
Name Solute carrier organic anion transporter family member 4C1
Gene Name SLCO4C1
Actions substrate
References
  • Mikkaichi T, Suzuki T, Onogawa T, Tanemoto M, Mizutamari H, Okada M, Chaki T, Masuda S, Tokui T, Eto N, Abe M, Satoh F, Unno M, Hishinuma T, Inui K, Ito S, Goto J, Abe T: Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney. Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3569-74. Epub 2004 Mar 1. - Pubmed
DTHybrid score 0.5238
Sodium/bile acid cotransporter
Name Sodium/bile acid cotransporter
Gene Name SLC10A1
Actions substrate
References
  • Friesema EC, Docter R, Moerings EP, Stieger B, Hagenbuch B, Meier PJ, Krenning EP, Hennemann G, Visser TJ: Identification of thyroid hormone transporters. Biochem Biophys Res Commun. 1999 Jan 19;254(2):497-501. - Pubmed
DTHybrid score 0.3208
Solute carrier organic anion transporter family member 1C1
Name Solute carrier organic anion transporter family member 1C1
Gene Name SLCO1C1
Actions substrate,inhibitor
References
  • Tohyama K, Kusuhara H, Sugiyama Y: Involvement of multispecific organic anion transporter, Oatp14 (Slc21a14), in the transport of thyroxine across the blood-brain barrier. Endocrinology. 2004 Sep;145(9):4384-91. Epub 2004 May 27. - Pubmed
  • Pizzagalli F, Hagenbuch B, Stieger B, Klenk U, Folkers G, Meier PJ: Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter. Mol Endocrinol. 2002 Oct;16(10):2283-96. - Pubmed
DTHybrid score 0.4897
Solute carrier organic anion transporter family member 4A1
Name Solute carrier organic anion transporter family member 4A1
Gene Name SLCO4A1
Actions substrate,inhibitor
References
  • Fujiwara K, Adachi H, Nishio T, Unno M, Tokui T, Okabe M, Onogawa T, Suzuki T, Asano N, Tanemoto M, Seki M, Shiiba K, Suzuki M, Kondo Y, Nunoki K, Shimosegawa T, Iinuma K, Ito S, Matsuno S, Abe T: Identification of thyroid hormone transporters in humans: different molecules are involved in a tissue-specific manner. Endocrinology. 2001 May;142(5):2005-12. - Pubmed
  • Mikkaichi T, Suzuki T, Onogawa T, Tanemoto M, Mizutamari H, Okada M, Chaki T, Masuda S, Tokui T, Eto N, Abe M, Satoh F, Unno M, Hishinuma T, Inui K, Ito S, Goto J, Abe T: Isolation and characterization of a digoxin transporter and its rat homologue expressed in the kidney. Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3569-74. Epub 2004 Mar 1. - Pubmed
  • Fujiwara K, Adachi H, Nishio T, Unno M, Tokui T, Okabe M, Onogawa T, Suzuki T, Asano N, Tanemoto M, Seki M, Shiiba K, Suzuki M, Kondo Y, Nunoki K, Shimosegawa T, Iinuma K, Ito S, Matsuno S, Abe T: Identification of thyroid hormone transporters in humans: different molecules are involved in a tissue-specific manner. Endocrinology. 2001 May;142(5):2005-12. - Pubmed
DTHybrid score 0.4713
Solute carrier family 22 member 8
Name Solute carrier family 22 member 8
Gene Name SLC22A8
Actions inhibitor
References
  • Ohtsuki S, Kikkawa T, Mori S, Hori S, Takanaga H, Otagiri M, Terasaki T: Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier. J Pharmacol Exp Ther. 2004 Jun;309(3):1273-81. Epub 2004 Feb 4. - Pubmed
DTHybrid score 0.4272
Monocarboxylate transporter 10
Name Monocarboxylate transporter 10
Gene Name SLC16A10
Actions inhibitor
References
  • Kim DK, Kanai Y, Chairoungdua A, Matsuo H, Cha SH, Endou H: Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. J Biol Chem. 2001 May 18;276(20):17221-8. Epub 2001 Feb 20. - Pubmed
DTHybrid score 0.5227
Multidrug resistance protein 1
Name Multidrug resistance protein 1
Gene Name ABCB1
Actions inducer
References
  • Ashida K, Katsura T, Motohashi H, Saito H, Inui K: Thyroid hormone regulates the activity and expression of the peptide transporter PEPT1 in Caco-2 cells. Am J Physiol Gastrointest Liver Physiol. 2002 Apr;282(4):G617-23. - Pubmed
DTHybrid score 0.5199
Large neutral amino acids transporter small subunit 1
Name Large neutral amino acids transporter small subunit 1
Gene Name SLC7A5
Actions Not Available
References
  • Uchino H, Kanai Y, Kim DK, Wempe MF, Chairoungdua A, Morimoto E, Anders MW, Endou H: Transport of amino acid-related compounds mediated by L-type amino acid transporter 1 (LAT1): insights into the mechanisms of substrate recognition. Mol Pharmacol. 2002 Apr;61(4):729-37. - Pubmed
DTHybrid score 0.7115

Carriers


Solute carrier organic anion transporter family member 1A2
Name Solute carrier organic anion transporter family member 1A2
Gene Name SLCO1A2
Actions
References Not Available
DTHybrid score 0.5372
Solute carrier organic anion transporter family member 1B1
Name Solute carrier organic anion transporter family member 1B1
Gene Name SLCO1B1
Actions
References Not Available
DTHybrid score 0.6234
Solute carrier organic anion transporter family member 1B3
Name Solute carrier organic anion transporter family member 1B3
Gene Name SLCO1B3
Actions
References Not Available
DTHybrid score 0.4884
Solute carrier organic anion transporter family member 4C1
Name Solute carrier organic anion transporter family member 4C1
Gene Name SLCO4C1
Actions
References Not Available
DTHybrid score 0.5238
Sodium/bile acid cotransporter
Name Sodium/bile acid cotransporter
Gene Name SLC10A1
Actions
References Not Available
DTHybrid score 0.3208
Solute carrier organic anion transporter family member 1C1
Name Solute carrier organic anion transporter family member 1C1
Gene Name SLCO1C1
Actions
References Not Available
DTHybrid score 0.4897
Solute carrier organic anion transporter family member 4A1
Name Solute carrier organic anion transporter family member 4A1
Gene Name SLCO4A1
Actions
References Not Available
DTHybrid score 0.4713
Solute carrier family 22 member 8
Name Solute carrier family 22 member 8
Gene Name SLC22A8
Actions
References Not Available
DTHybrid score 0.4272
Monocarboxylate transporter 10
Name Monocarboxylate transporter 10
Gene Name SLC16A10
Actions
References Not Available
DTHybrid score 0.5227
Multidrug resistance protein 1
Name Multidrug resistance protein 1
Gene Name ABCB1
Actions
References Not Available
DTHybrid score 0.5199
Large neutral amino acids transporter small subunit 1
Name Large neutral amino acids transporter small subunit 1
Gene Name SLC7A5
Actions
References Not Available
DTHybrid score 0.7115

Predictions


Id Partner name Gene Name Score
4512 Cytochrome P450 3A4 CYP3A4 0.2978
4924 Cytochrome P450 2C8 CYP2C8 0.2323
1729 Solute carrier family 22 member 6 SLC22A6 0.2054
199 Monocarboxylate transporter 8 SLC16A2 0.1962
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.1633
4757 Cytochrome P450 2C9 CYP2C9 0.1519
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.1492
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.1472
1024 Solute carrier family 22 member 11 SLC22A11 0.1436
776 Bile salt export pump ABCB11 0.1355
6016 Cytochrome P450 2C19 CYP2C19 0.1326
4118 Cytochrome P450 3A5 CYP3A5 0.1308
862 Multidrug resistance-associated protein 1 ABCC1 0.125
6369 Thyroid hormone receptor, alpha isoform 1 variant Not Available 0.1207
563 Thyroid peroxidase TPO 0.116
2164 Multidrug resistance-associated protein 4 ABCC4 0.1157
6143 Solute carrier family 22 member 7 SLC22A7 0.1102
4119 Cytochrome P450 2D6 CYP2D6 0.1081
4200 Cytochrome P450 1A2 CYP1A2 0.108
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.1024
1566 Corticoliberin CRH 0.0993
866 Large neutral amino acids transporter small subunit 2 SLC7A8 0.0954
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0909
6145 Solute carrier family 22 member 1 SLC22A1 0.0898
6167 Organic solute transporter subunit beta OSTB 0.0878
6166 Organic solute transporter subunit alpha OSTA 0.0878
6147 Solute carrier family 22 member 3 SLC22A3 0.082
6107 Cytochrome P450 3A7 CYP3A7 0.0808
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0793
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0777
6024 Cytochrome P450 1A1 CYP1A1 0.0766
20 Prostaglandin G/H synthase 1 PTGS1 0.0741
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0726
6030 Cytochrome P450 2B6 CYP2B6 0.07
290 Prostaglandin G/H synthase 2 PTGS2 0.0698
6556 Elongation factor Tu GTP-binding domain-containing protein 1 EFTUD1 0.0665
3587 Gastrotropin FABP6 0.0651
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0649
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0644
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0636
301 Kynurenine--oxoglutarate transaminase 1 CCBL1 0.0578
738 Monocarboxylate transporter 1 SLC16A1 0.0556
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0555
136 Estrogen receptor ESR1 0.0539
118 Organic cation/carnitine transporter 2 SLC22A5 0.0536
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0535
6148 Multidrug resistance-associated protein 7 ABCC10 0.0513
6144 Solute carrier family 22 member 2 SLC22A2 0.0496
33 Cystine/glutamate transporter SLC7A11 0.0484
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0445
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0445
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0445
833 Organic cation/carnitine transporter 1 SLC22A4 0.0427
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0414
6013 Cytochrome P450 2E1 CYP2E1 0.0411
70 Type-1 angiotensin II receptor AGTR1 0.0389
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0383
1898 Cytochrome P450 1B1 CYP1B1 0.0367
6136 Multidrug resistance-associated protein 5 ABCC5 0.0362
6149 Solute carrier family 22 member 10 SLC22A10 0.0355
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.035
756 Sex hormone-binding globulin SHBG 0.0323
3811 Cytochrome P450 19A1 CYP19A1 0.0308
4604 Liver carboxylesterase 1 CES1 0.0295
2532 Pantoate--beta-alanine ligase panC 0.0285
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0275
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0274
5718 Cytochrome P450 2A6 CYP2A6 0.0268
869 Estrogen receptor beta ESR2 0.0266
574 Branched-chain-amino-acid aminotransferase, cytosolic BCAT1 0.0262
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.026
6645 D-amino-acid oxidase DAO 0.0259
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0252
952 Dipeptidyl peptidase 4 DPP4 0.0251
831 D(2) dopamine receptor DRD2 0.0251
1275 Estrogen sulfotransferase SULT1E1 0.0249
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0238
275 Arachidonate 5-lipoxygenase ALOX5 0.0233
5925 Neuropeptide Y NPY 0.0231
314 System N amino acid transporter 1 SLC38A3 0.0229
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0226
23 D(1A) dopamine receptor DRD1 0.0222
146 Androgen receptor AR 0.0222
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0221
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0218
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0212
244 Angiotensin-converting enzyme ACE 0.0212
6085 Fatty acid-binding protein, intestinal FABP2 0.0208
891 Dihydropteroate synthase folP 0.0207
5359 Dihydropteroate synthase folP 0.0207
7175 Dihydropteroate synthase sulI 0.0207
6106 Cytochrome P450 2C18 CYP2C18 0.0203
871 Glucocorticoid receptor NR3C1 0.0201
4069 Threonyl-tRNA synthetase, mitochondrial TARS2 0.0197
261 Threonyl-tRNA synthetase, cytoplasmic TARS 0.0197
246 Valyl-tRNA synthetase VARS 0.0196
731 HIV-1 protease HIV-1 protease 0.0193
6258 Protein S100-A7 S100A7 0.0191
492 Histamine H1 receptor HRH1 0.019
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0185
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0184
578 Endothelin-1 receptor EDNRA 0.0182
5818 Folate receptor alpha FOLR1 0.018
3810 Catechol O-methyltransferase COMT 0.018
6020 Aldehyde oxidase AOX1 0.0179
489 Monocarboxylate transporter 2 SLC16A7 0.0177
29 Tubulin beta-1 chain TUBB1 0.0176
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.0174
5756 D-alanyl-D-alanine carboxypeptidase dac 0.0174
6137 Multidrug resistance-associated protein 6 ABCC6 0.0172
556 Alpha-1A adrenergic receptor ADRA1A 0.0171
1389 Transforming growth factor beta-1 TGFB1 0.0169
5469 Head decoration protein shp 0.0168
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0168
471 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 0.0167
763 Tyrosine aminotransferase TAT 0.0167
5493 Tyrosine aminotransferase Not Available 0.0167
2183 Fatty acid-binding protein, adipocyte FABP4 0.0165
638 D(3) dopamine receptor DRD3 0.0164
2457 Bacillolysin nprS 0.016
558 Solute carrier family 12 member 1 SLC12A1 0.0159
543 Penicillin-binding protein 1B mrcB 0.0158
6186 Penicillin-binding protein 1B ponB 0.0158
6822 Penicillin-binding protein 1b pbp1b 0.0158
6844 Penicillin-binding protein 1b pbp1b 0.0158
601 Propionyl-CoA carboxylase beta chain, mitochondrial PCCB 0.0157
293 Gamma-glutamyl hydrolase GGH 0.0157
645 Penicillin-binding protein 1A mrcA 0.0155
5805 Penicillin-binding protein 1A ponA 0.0155
6185 Penicillin-binding protein 1A mrcA 0.0155
6799 Penicillin-binding protein 1A pbpA 0.0155
482 Glycine receptor subunit alpha-1 GLRA1 0.0154
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0152
534 Threonine synthase-like 1 THNSL1 0.0152
163 D(1B) dopamine receptor DRD5 0.0151
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.015
2261 Major NAD(P)H-flavin oxidoreductase Not Available 0.0149
676 Tyrosine 3-monooxygenase TH 0.0149
432 D(4) dopamine receptor DRD4 0.0149
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0149
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0147
815 Histidyl-tRNA synthetase, cytoplasmic HARS 0.0147
96 Histidine ammonia-lyase HAL 0.0147
6257 Histidine ammonia-lyase Not Available 0.0147
6536 Histidine ammonia-lyase hutH 0.0147
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0147
320 5-hydroxytryptamine 1A receptor HTR1A 0.0147
3917 Methylenetetrahydrofolate reductase MTHFR 0.0147
3923 Cholinesterase BCHE 0.0145
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0144
6541 Peptostreptococcal albumin-binding protein pab 0.0142
38 Cystinosin CTNS 0.0141
3998 B(0,+)-type amino acid transporter 1 SLC7A9 0.0141
1963 Neutral and basic amino acid transport protein rBAT SLC3A1 0.0141
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.014
904 Glutathione S-transferase P GSTP1 0.014
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0139
1650 Heme carrier protein 1 SLC46A1 0.0139
737 Mineralocorticoid receptor NR3C2 0.0139
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0138
380 Cytochrome P450 17A1 CYP17A1 0.0138
150 Cationic amino acid transporter 3 SLC7A3 0.0137
235 High-affinity cationic amino acid transporter 1 SLC7A1 0.0137
58 Cationic amino acid transporter 4 SLC7A4 0.0137
663 Solute carrier family 12 member 4 SLC12A4 0.0136
53 Solute carrier family 12 member 5 SLC12A5 0.0136
502 5-hydroxytryptamine 2A receptor HTR2A 0.0136
6218 Pannexin-1 PANX1 0.0132
520 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.0132
2306 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.0132
2367 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.0132
124 Histamine H2 receptor HRH2 0.013
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0129
399 Tyrosyl-tRNA synthetase, mitochondrial YARS2 0.0127
310 Solute carrier family 12 member 2 SLC12A2 0.0127
824 Sodium-dependent serotonin transporter SLC6A4 0.0127
24 Thymidylate synthase TMP1 0.0126
359 Thymidylate synthase TYMS 0.0126
2626 Thymidylate synthase thyA 0.0126
2729 Thymidylate synthase thyA 0.0126
5352 Thymidylate synthase THYA 0.0126
3809 Estrogen-related receptor gamma ESRRG 0.0126
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0126
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0125
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0122
3941 Amine oxidase [flavin-containing] A MAOA 0.0122
193 Beta-1 adrenergic receptor ADRB1 0.0121
632 Alpha-1B adrenergic receptor ADRA1B 0.0121
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0121
3977 ASRGL1 protein ASRGL1 0.0121
4094 Gamma-aminobutyric acid type B receptor, subunit 2 GABBR2 0.0119
263 Neutral amino acid transporter B(0) SLC1A5 0.0119
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0117
3 Histidine decarboxylase HDC 0.0117
3947 Xanthine dehydrogenase/oxidase XDH 0.0117
2981 Phospholipase A2, membrane associated PLA2G2A 0.0116
2539 Tubulin alpha-1 chain TUBA4A 0.0116
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0115
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0115
2016 Dipeptidase 1 DPEP1 0.0115
349 Serine--pyruvate aminotransferase AGXT 0.0115
6031 Cytochrome P450 3A43 CYP3A43 0.0113
701 Isoleucine-tRNA synthetase IARS 0.011
546 Isoleucyl-tRNA synthetase, cytoplasmic IARS 0.011
4080 Isoleucyl-tRNA synthetase, mitochondrial IARS2 0.011
2391 Ferrochelatase hemH 0.0109
6502 Ferrochelatase DKFZp686P18130 0.0109
1591 Ferrochelatase, mitochondrial FECH 0.0109
221 Lysyl-tRNA synthetase KARS 0.0109
468 Cytochrome P450 4A11 CYP4A11 0.0108
358 Cystathionine beta-synthase CBS 0.0108
4092 Probable asparaginyl-tRNA synthetase, mitochondrial NARS2 0.0107
669 Asparaginyl-tRNA synthetase, cytoplasmic NARS 0.0107
273 Apoptosis regulator Bcl-2 BCL2 0.0107
365 Dihydrofolate reductase DHFR 0.0107
2381 Dihydrofolate reductase DFR1 0.0107
2833 Dihydrofolate reductase Not Available 0.0107
2931 Dihydrofolate reductase folA 0.0107
3544 Dihydrofolate reductase folA 0.0107
3682 Dihydrofolate reductase folA 0.0107
6642 Dihydrofolate reductase folA 0.0107
6756 Dihydrofolate reductase dfrA 0.0107
2211 Fatty acid-binding protein, heart FABP3 0.0105
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0104
1 Peptidoglycan synthetase ftsI ftsI 0.0104
4155 Peptidoglycan synthetase ftsI ftsI 0.0104
1517 Beta-3 adrenergic receptor ADRB3 0.0102
5650 NimA-related protein DR_0842 0.0101
22 30S ribosomal protein S4 rpsD 0.0101
6714 30S ribosomal protein S4 rpsD 0.0101
3426 Glutamine synthetase glnA 0.0101
3987 Glutamine synthetase GLUL 0.0101
6501 Fatty acid-binding protein, liver FABP1 0.0101
338 DNA polymerase UL30 0.01
379 DNA polymerase UL54 0.01
697 DNA polymerase ORF28 0.01
2482 DNA polymerase 43 0.01
4104 DNA polymerase BALF5 0.01
72 Seryl-tRNA synthetase, cytoplasmic SARS 0.0099
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0098
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0098
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0097
501 Leucine carboxyl methyltransferase 1 LCMT1 0.0097
675 Leucine carboxyl methyltransferase 2 LCMT2 0.0097
846 Leucyl-tRNA synthetase, cytoplasmic LARS 0.0097
227 Probable leucyl-tRNA synthetase, mitochondrial LARS2 0.0097
42 Phenylalanyl-tRNA synthetase alpha chain FARSA 0.0096
6602 Phenylalanyl-tRNA synthetase alpha chain pheS 0.0096
31 Phenylalanyl-tRNA synthetase, mitochondrial FARS2 0.0096
618 Phenylalanyl-tRNA synthetase beta chain FARSB 0.0096
6603 Phenylalanyl-tRNA synthetase beta chain pheT 0.0096
140 30S ribosomal protein S9 rpsI 0.0095
6719 30S ribosomal protein S9 rpsI 0.0095
6725 30S ribosomal protein S9 rpsI 0.0095
619 Low-affinity cationic amino acid transporter 2 SLC7A2 0.0095
566 Serotransferrin TF 0.0094
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.0094
6493 Cytochrome c oxidase subunit 6C COX6C 0.0094
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.0094
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.0094
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.0094
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.0094
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.0094
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.0094
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.0094
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0094
6559 Cytochrome c oxidase subunit 2 ctaC 0.0094
6669 Cytochrome c oxidase subunit 2 ctaC 0.0094
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.0094
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0094
371 Cytochrome c oxidase subunit 1 MT-CO1 0.0094
6558 Cytochrome c oxidase subunit 1 ctaD 0.0094
1852 Microtubule-associated protein 2 MAP2 0.0094
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0094
766 Beta-2 adrenergic receptor ADRB2 0.0094
240 Gamma-aminobutyric acid type B receptor, subunit 1 GABBR1 0.0093
828 Phenylalanine-4-hydroxylase PAH 0.0092
3109 Phenylalanine-4-hydroxylase phhA 0.0092
844 Epidermal growth factor receptor EGFR 0.0091
817 DNA topoisomerase 2-alpha TOP2A 0.0091
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0091
847 Mu-type opioid receptor OPRM1 0.009
789 Alpha-1D adrenergic receptor ADRA1D 0.009
725 5-hydroxytryptamine 1D receptor HTR1D 0.0089
885 5-hydroxytryptamine 1B receptor HTR1B 0.0089
6043 Putative G-protein coupled receptor 44 GPR44 0.0089
256 Tyrosyl-tRNA synthetase, cytoplasmic YARS 0.0089
614 Progesterone receptor PGR 0.0088
114 Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 0.0087
500 Monocarboxylate transporter 4 SLC16A3 0.0087
2540 Choloylglycine hydrolase cbh 0.0086
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0086
5923 Microtubule-associated protein tau MAPT 0.0085
5924 Microtubule-associated protein 4 MAP4 0.0085
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0085
26 Vascular endothelial growth factor receptor 3 FLT4 0.0085
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0084
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0084
511 5-hydroxytryptamine 1F receptor HTR1F 0.0082
6033 High affinity interleukin-8 receptor A CXCR1 0.0082
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0082
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0081
696 Kappa-type opioid receptor OPRK1 0.0081
169 Cysteine desulfurase, mitochondrial NFS1 0.0081
32 Vascular endothelial growth factor receptor 1 FLT1 0.0081
5880 Thrombopoietin receptor MPL 0.0081
6525 Group IID secretory phospholipase A2 PLA2G2D 0.008
1119 Peroxiredoxin-5, mitochondrial PRDX5 0.0079
115 Penicillin-binding protein 2 mrdA 0.0079
6069 Penicillin-binding protein 2 mrdA 0.0079
6118 Penicillin-binding protein 2 penA 0.0079
6187 Penicillin-binding protein 2 pbpA 0.0079
6686 Penicillin-binding protein 2 pbp2 0.0079
6939 Penicillin-binding protein 2 mrdA 0.0079
7163 Penicillin-binding protein 2 pbpA 0.0079
6042 Prostaglandin reductase 2 PTGR2 0.0078
183 Vascular endothelial growth factor A VEGFA 0.0078
318 Alpha-2A adrenergic receptor ADRA2A 0.0078
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0077
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0077
1353 DNA topoisomerase 1 TOP1 0.0077
3552 DNA topoisomerase 1 topA 0.0077
765 Indoleamine 2,3-dioxygenase IDO1 0.0076
889 3-oxoacyl-[acyl-carrier-protein] synthase 1 fabB 0.0076
6860 3-oxoacyl-[acyl-carrier-protein] synthase 1 kasA 0.0076
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0076
184 L-serine dehydratase SDS 0.0076
431 Serine racemase SRR 0.0076
491 Serine palmitoyltransferase 1 SPTLC1 0.0076
727 Serine palmitoyltransferase 2 SPTLC2 0.0076
467 Delta-type opioid receptor OPRD1 0.0076
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0076
90 Tryptophan 5-hydroxylase 2 TPH2 0.0073
4063 Tryptophanyl-tRNA synthetase, mitochondrial WARS2 0.0073
5626 Nucleoside diphosphate kinase B NME2 0.0072
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0072
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0072
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0071
465 Calmodulin CALM1 0.0071
438 Taste receptor type 1 member 2 TAS1R2 0.0071
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0071
633 Penicillin-binding proteins 1A/1B pbpA 0.007
6014 Cytochrome P450 2A13 CYP2A13 0.0069
407 Vascular endothelial growth factor receptor 2 KDR 0.0069
740 Argininosuccinate synthase ASS1 0.0069
865 Argininosuccinate synthase ASS1 0.0069
2680 Argininosuccinate synthase argG 0.0069
3194 Argininosuccinate synthase argG 0.0069
705 Glutamate receptor 1 GRIA1 0.0067
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0067
6500 Phospholipase A2 PLA2G1B 0.0066
6184 D-alanyl-D-alanine carboxypeptidase dacC dacC 0.0066
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0066
36 Insulin receptor INSR 0.0066
768 FK506-binding protein 1A FKBP1A 0.0066
3686 Acyl-CoA thioesterase I precursor tesA 0.0065
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0065
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0065
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0064
1525 Heparin-binding growth factor 2 FGF2 0.0064
4238 50S ribosomal protein L4 rplD 0.0064
5578 50S ribosomal protein L4 rplD 0.0064
6173 50S ribosomal protein L4 rplD 0.0064
6219 50S ribosomal protein L4 rplD 0.0064
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0064
1867 Major prion protein PRNP 0.0064
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0063
537 ATP synthase delta chain, mitochondrial ATP5D 0.0063
3432 Multidrug-efflux transporter 1 regulator bmrR 0.0063
4476 Mannitol dehydrogenase mtlD 0.0063
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0063
122 P2Y purinoceptor 12 P2RY12 0.0063
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0062
4210 Toll-like receptor 4 TLR4 0.0062
629 Alpha-2B adrenergic receptor ADRA2B 0.0061
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0061
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0061
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0061
1313 Lactoylglutathione lyase GLO1 0.0061
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0061
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.006
504 Mast/stem cell growth factor receptor KIT 0.006
51 Muscarinic acetylcholine receptor M3 CHRM3 0.006
1405 Thiopurine S-methyltransferase TPMT 0.0059
252 Tryptophanyl-tRNA synthetase, cytoplasmic WARS 0.0059
5294 Nucleoside diphosphate kinase A NME1 0.0059
4237 50S ribosomal protein L22 rplV 0.0059
4148 Serine/threonine-protein kinase mTOR MTOR 0.0059
1291 cAMP response element-binding protein CREB1 0.0059
3382 Glycolipid transfer protein GLTP 0.0058
517 Alcohol dehydrogenase 1C ADH1C 0.0058
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0058
532 Neutral amino acid transporter A SLC1A4 0.0057
4070 Probable alanyl-tRNA synthetase, mitochondrial AARS2 0.0057
323 Alanyl-tRNA synthetase, cytoplasmic AARS 0.0057
887 DNA gyrase subunit B gyrB 0.0057
4150 DNA gyrase subunit B gyrB 0.0057
6225 DNA gyrase subunit B gyrB 0.0057
2452 Tryptophanyl-tRNA synthetase trpS 0.0056
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0056
6220 Aryl hydrocarbon receptor AHR 0.0055
1630 Integrin beta-2 ITGB2 0.0055
260 Cytochrome P450 51 ERG11 0.0055
761 Cytochrome P450 51 ERG11 0.0055
3163 Cytochrome P450 51 cyp51 0.0055
1558 Transient receptor potential cation channel subfamily V member 1 TRPV1 0.0055
341 5-hydroxytryptamine 3 receptor HTR3A 0.0055
6209 30S ribosomal protein S19 rpsS 0.0055
6712 30S ribosomal protein S19 rpsS 0.0055
6726 30S ribosomal protein S19 rpsS 0.0055
1192 Sulfotransferase 1A1 SULT1A1 0.0055
6207 30S ribosomal protein S14 rpsN 0.0055
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0055
134 Tryptophan 5-hydroxylase 1 TPH1 0.0055
109 Mitochondrial carnitine/acylcarnitine carrier protein CACL SLC25A29 0.0054
378 Alpha-2C adrenergic receptor ADRA2C 0.0054
636 Mitochondrial carnitine/acylcarnitine carrier protein SLC25A20 0.0054
668 Glutamate--cysteine ligase regulatory subunit GCLM 0.0054
992 Protein tyrosine kinase 2 beta PTK2B 0.0054
5353 Glutamate decarboxylase alpha gadA 0.0054
6012 Tryptophan 2,3-dioxygenase TDO2 0.0053
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0053
819 Penicillin-binding protein 4 dacB 0.0053
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0053
2853 14 kDa fatty acid-binding protein Not Available 0.0053
469 Annexin A1 ANXA1 0.0053
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0053
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0053
171 Cysteine dioxygenase CDO-1 0.0053
774 Cysteinyl-tRNA synthetase, cytoplasmic CARS 0.0052
1314 Thiamine transporter 2 SLC19A3 0.0052
4064 Probable cysteinyl-tRNA synthetase, mitochondrial CARS2 0.0052
6182 Cytochrome P450 2J2 CYP2J2 0.0052
207 Glutathione synthetase GSS 0.0052
5269 Glutathione synthetase gshB 0.0052
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0052
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0051
228 Beta platelet-derived growth factor receptor PDGFRB 0.0051
834 Arginase-2, mitochondrial ARG2 0.0051
593 Proton-coupled amino acid transporter 1 SLC36A1 0.0051
6168 Solute carrier family 22 member 16 SLC22A16 0.0051
2616 Ganglioside GM2 activator GM2A 0.0051
232 Corticosteroid-binding globulin SERPINA6 0.005
950 Alpha platelet-derived growth factor receptor PDGFRA 0.005
3760 Penicillin-binding protein 5 precursor dacA 0.005
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.005
436 5-hydroxytryptamine 2B receptor HTR2B 0.005
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.005
6027 Alkaline phosphatase, tissue-nonspecific isozyme ALPL 0.005
2021 Thrombomodulin THBD 0.0049
577 Argininosuccinate lyase ASL 0.0049
1141 Sialidase-1 NEU1 0.0049
64 Neuraminidase NA 0.0049
641 Neuraminidase NA 0.0049
2676 Neuraminidase NA 0.0049
3026 Neuraminidase NA 0.0049
3519 Neuraminidase NA 0.0049
6007 Neuraminidase NA 0.0049
499 Arginine decarboxylase ADC 0.0049
3971 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase CAD 0.0049
284 DNA-directed RNA polymerase beta chain rpoB 0.0049
5773 DNA-directed RNA polymerase beta chain rpoB 0.0049
480 Methionine-R-sulfoxide reductase B2 MSRB2 0.0048
317 Methionine-R-sulfoxide reductase SEPX1 0.0048
3996 Betaine--homocysteine S-methyltransferase 2 BHMT2 0.0048
3921 Methionine adenosyltransferase 2 subunit beta MAT2B 0.0048
3995 Methionyl-tRNA synthetase, mitochondrial MARS2 0.0048
600 Methionyl-tRNA synthetase, cytoplasmic MARS 0.0048
751 Potassium channel subfamily K member 6 KCNK6 0.0047
1198 Serum paraoxonase/arylesterase 1 PON1 0.0047
6223 Penicillin-binding protein 1C pbpC 0.0047
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0047
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0047
412 Peroxisomal carnitine O-octanoyltransferase CROT 0.0046
186 Glutamate--cysteine ligase catalytic subunit GCLC 0.0046
551 Carnitine O-acetyltransferase CRAT 0.0046
6228 Nuclear receptor coactivator 1 NCOA1 0.0046
332 Beta-lactamase blaZ 0.0046
2478 Beta-lactamase ampC 0.0046
2613 Beta-lactamase ampC 0.0046
2635 Beta-lactamase ampC 0.0046
2700 Beta-lactamase penP 0.0046
5445 Beta-lactamase blaB 0.0046
6019 Beta-lactamase SHV-7 0.0046
6701 Beta-lactamase cphA 0.0046
65 Matrix metalloproteinase-9 Not Available 0.0046
735 Alanine aminotransferase 1 GPT 0.0046
3904 Alanine aminotransferase 2 GPT2 0.0046
7 Nitric oxide synthase, inducible NOS2 0.0045
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0045
1757 Myeloperoxidase MPO 0.0045
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0045
2236 Casein kinase II subunit alpha CSNK2A1 0.0045
6044 Serum paraoxonase/lactonase 3 PON3 0.0045
3899 Alanine--glyoxylate aminotransferase 2-like 2 AGXT2L2 0.0044
5645 DNA topoisomerase 4 subunit B parE 0.0044
6227 DNA topoisomerase 4 subunit B parE 0.0044
4120 NADPH--cytochrome P450 reductase POR 0.0043
172 Potassium channel subfamily K member 1 KCNK1 0.0043
1999 Methylated-DNA--protein-cysteine methyltransferase MGMT 0.0043
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0043
6241 Nuclear receptor coactivator 2 NCOA2 0.0043
342 P protein [Includes: DNA-directed DNA polymerase P 0.0042
612 P protein [Includes: DNA-directed DNA polymerase P 0.0042
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0042
572 Integrin alpha-L ITGAL 0.0042
590 5-hydroxytryptamine 2C receptor HTR2C 0.0042
435 Kynureninase KYNU 0.0041
4654 Kynureninase kynU 0.0041
397 Monocarboxylate transporter 3 SLC16A8 0.0041
218 Monocarboxylate transporter 5 SLC16A4 0.0041
195 Monocarboxylate transporter 7 SLC16A6 0.0041
429 Monocarboxylate transporter 6 SLC16A5 0.0041
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0041
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0041
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0041
3688 Branched-chain-amino-acid aminotransferase ilvE 0.0041
191 Peptide methionine sulfoxide reductase MSRA 0.0041
1760 Aminopeptidase N ANPEP 0.0041
6843 Aminopeptidase N pepN 0.0041
89 Cysteine sulfinic acid decarboxylase CSAD 0.004
4000 Prolyl 4-hydroxylase subunit alpha-2 P4HA2 0.004
6508 Putative uncharacterized protein srtB 0.004
6543 Putative uncharacterized protein tcp14 0.004
6615 Putative uncharacterized protein MT0785 0.004
6623 Putative uncharacterized protein Not Available 0.004
6806 Putative uncharacterized protein AGR_C_2535 0.004
6813 Putative uncharacterized protein SAV4671 0.004
6815 Putative uncharacterized protein AFE_1514 0.004
6819 Putative uncharacterized protein RUMGNA_03254 0.004
6825 Putative uncharacterized protein CV_3270 0.004
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.004
4161 Furin FURIN 0.004
626 Cysteine dioxygenase type 1 CDO1 0.004
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.004
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.004
474 Acetylcholinesterase ACHE 0.004
161 Tubulin beta chain TUBB 0.0039
312 Tubulin beta chain TUB2 0.0039
5482 Sialidase-2 NEU2 0.0039
117 Sterol O-acyltransferase 1 SOAT1 0.0039
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0039
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0039
334 S-adenosylmethionine synthetase isoform type-2 MAT2A 0.0038
6067 Penicillin binding protein 2a mecA 0.0038
6677 Myelin P2 protein PMP2 0.0038
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0038
3685 Catabolite gene activator crp 0.0038
4655 Adenylate cyclase cyaC 0.0038
4759 Adenylate cyclase cyaB2 0.0038
585 Aspartyl/asparaginyl beta-hydroxylase ASPH 0.0038
4122 Histone deacetylase 2 HDAC2 0.0038
3932 Glutathione S-transferase A2 GSTA2 0.0038
5934 Cytochrome P450 26A1 CYP26A1 0.0038
459 Retinoic acid receptor RXR-alpha RXRA 0.0037
4217 Telomerase reverse transcriptase TERT 0.0037
3856 Fibroblast growth factor receptor 3 FGFR3 0.0037
2472 Voltage-gated potassium channel kcsA 0.0037
6366 Voltage-gated potassium channel kcsA 0.0037
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0037
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0037
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0036
130 Prostacyclin synthase PTGIS 0.0036
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0036
3949 Prolyl 3-hydroxylase 2 LEPREL1 0.0036
3945 Prolyl 3-hydroxylase 1 LEPRE1 0.0036
3951 Prolyl 3-hydroxylase 3 LEPREL2 0.0036
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0035
52 Pyruvate kinase isozymes R/L PKLR 0.0035
477 DNA topoisomerase 4 subunit A parC 0.0035
886 DNA topoisomerase 4 subunit A parC 0.0035
6226 DNA topoisomerase 4 subunit A parC 0.0035
868 Cystathionine gamma-lyase CTH 0.0035
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0035
2449 Tubulin alpha-3 chain TUBA1A 0.0035
6171 Solute carrier family 28 member 3 SLC28A3 0.0035
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0035
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0035
404 DNA gyrase subunit A gyrA 0.0035
6224 DNA gyrase subunit A gyrA 0.0035
509 Thymidine kinase TK 0.0035
570 Thymidine kinase TK 0.0035
2559 Thymidine kinase TK 0.0035
3430 Thymidine kinase tdk 0.0035
3518 Thymidine kinase TK 0.0035
5301 Thymidine kinase tdk 0.0035
5771 Thymidine kinase ORF36 0.0035
7009 Thymidine kinase ORF36 0.0035
4085 Peptidyl-prolyl cis-trans isomerase C PPIC 0.0035
4088 Probable prolyl-tRNA synthetase, mitochondrial PARS2 0.0035
4083 Peptidyl-prolyl cis-trans isomerase H PPIH 0.0035
4087 Pyrroline 5-carboxylate reductase isoform P5CR2 0.0035
4090 Chromosome 14 open reading frame 149 C14orf149 0.0035
4082 Proline oxidase, mitochondrial PRODH 0.0035
797 Sodium-dependent proline transporter SLC6A7 0.0035
4086 Peptidyl-prolyl cis-trans isomerase G PPIG 0.0035
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0034
811 Translocator protein TSPO 0.0034
3991 Glutamine-dependent NAD(+) synthetase NADSYN1 0.0034
3984 Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial PET112L 0.0034
5 Glutaminase liver isoform, mitochondrial GLS2 0.0034
917 Glutaminase kidney isoform, mitochondrial GLS 0.0034
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0034
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0034
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0034
5261 Phosphoribosylformylglycinamidine synthase purL 0.0034
1792 Tissue-type plasminogen activator PLAT 0.0034
291 Nitric-oxide synthase, endothelial NOS3 0.0034
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0034
771 Pyruvate carboxylase, mitochondrial PC 0.0034
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0034
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0034
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0033
1656 CYP2B protein CYP2B 0.0033
2178 Metabotropic glutamate receptor 5 GRM5 0.0033
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0033
2249 Aspartate aminotransferase aspC 0.0033
2671 Aspartate aminotransferase aspC 0.0033
5490 Aspartate aminotransferase Not Available 0.0033
1671 Excitatory amino acid transporter 3 SLC1A1 0.0033
413 Amidophosphoribosyltransferase PPAT 0.0033
2515 Amidophosphoribosyltransferase purF 0.0033
3714 Amidophosphoribosyltransferase purF 0.0033
840 Methionine synthase reductase, mitochondrial MTRR 0.0033
707 72 kDa type IV collagenase MMP2 0.0033
4760 Mll3241 protein mll3241 0.0032
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0032
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0032
3939 Amine oxidase [flavin-containing] B MAOB 0.0032
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0032
5682 Ribonuclease pancreatic RNASE1 0.0032
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0032
595 Fibrinogen alpha chain FGA 0.0032
98 Pyruvate kinase isozymes M1/M2 PKM2 0.0032
3877 Growth-inhibiting protein 18 GIG18 0.0031
210 Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase EPRS 0.0031
2632 Adenylosuccinate synthetase purA 0.0031
3323 Adenylosuccinate synthetase purA 0.0031
3975 Adenylosuccinate synthetase ADSS 0.0031
4598 Adenylosuccinate synthetase Adss 0.0031
6817 Adenylosuccinate synthetase purA 0.0031
3972 Adenylosuccinate synthetase isozyme 2 ADSS 0.0031
2499 Tubulin beta-2C chain TUBB2C 0.0031
533 Aminoacylase-1 ACY1 0.0031
3969 Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole- succinocarboxamide synthase PAICS 0.0031
799 Aspartyl-tRNA synthetase, cytoplasmic DARS 0.0031
209 Aspartoacylase ASPA 0.0031
3979 Aspartoacylase-2 ACY3 0.0031
3976 Aspartyl-tRNA synthetase, mitochondrial DARS2 0.0031
513 Calcium-binding mitochondrial carrier protein Aralar2 SLC25A13 0.0031
305 Mitochondrial aspartate-glutamate carrier protein SLC25A13 0.0031
262 Calcium-binding mitochondrial carrier protein Aralar1 SLC25A12 0.0031
809 Methionine synthase MTR 0.0031
2935 Methionine synthase metH 0.0031
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0031
5849 cAMP-dependent protein kinase type I-alpha regulatory subunit PRKAR1A 0.003
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.003
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.003
426 Aspartate aminotransferase, mitochondrial GOT2 0.003
976 Platelet glycoprotein IX GP9 0.003
2320 Thymidine kinase, cytosolic TK1 0.003
4084 Peptidyl-prolyl cis-trans isomerase B PPIB 0.003
3813 Fibrinogen gamma chain FGG 0.0029
3812 Fibrinogen beta chain [Contains: Fibrinopeptide B] FGB 0.0029
527 Prostacyclin receptor PTGIR 0.0029
1008 CTP synthase 1 CTPS 0.0029
3988 Protein-glutamine gamma-glutamyltransferase K TGM1 0.0029
3985 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 GFPT2 0.0029
3990 Protein-glutamine gamma-glutamyltransferase 4 TGM4 0.0029
3986 Protein-glutamine gamma-glutamyltransferase 6 TGM6 0.0029
3992 Protein-glutamine gamma-glutamyltransferase Z TGM7 0.0029
3983 Protein-glutamine gamma-glutamyltransferase 5 TGM5 0.0029
3989 Glutaminyl-tRNA synthetase QARS 0.0029
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0029
683 Potassium transporter GK0582 0.0029
672 Prostaglandin F2-alpha receptor PTGFR 0.0028
1435 Synaptic vesicle glycoprotein 2A SV2A 0.0028
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0028
1010 Cytochrome P450 51A1 CYP51A1 0.0028
1278 Pro-epidermal growth factor EGF 0.0028
6138 Multidrug resistance protein 3 ABCB4 0.0028
5126 Arginase rocF 0.0027
6232 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short GNAS 0.0027
6233 Adenylate cyclase type 2 ADCY2 0.0027
6234 Adenylate cyclase type 5 ADCY5 0.0027
777 Tumor necrosis factor TNF 0.0027
3874 Proline synthetase co-transcribed bacterial homolog protein PROSC 0.0027
2300 Lysozyme E 0.0027
3633 Lysozyme R 0.0027
5597 Lysozyme 17 0.0027
867 Penicillin-binding protein 3 pbpC 0.0027
6119 Penicillin-binding protein 3 pbp3 0.0027
7154 Penicillin-binding protein 3 pbp3 0.0027
7157 Penicillin-binding protein 3 LMHCC_2184 0.0027
7162 Penicillin-binding protein 3 pbpB 0.0027
7172 Penicillin-binding protein 3 pbp3 0.0027
5787 Angiopoietin-1 receptor TEK 0.0027
6102 Arylamine N-acetyltransferase 2 NAT2 0.0027
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0027
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0027
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0027
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0027
2554 Peptidyl-prolyl cis-trans isomerase, mitochondrial PPIF 0.0027
1654 Interleukin-1 beta IL1B 0.0026
818 50S ribosomal protein L10 rplJ 0.0026
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0026
2795 Methionine aminopeptidase 2 METAP2 0.0026
87 Hypoxanthine-guanine phosphoribosyltransferase HPRT1 0.0026
6599 HTH-type transcriptional regulator ttgR ttgR 0.0026
5997 Tumor necrosis factor ligand superfamily member 11 TNFSF11 0.0026
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0026
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0026
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0026
461 Glycine receptor subunit alpha-3 GLRA3 0.0025
716 5-hydroxytryptamine 7 receptor HTR7 0.0025
6432 Transporter snf 0.0025
1050 Bile salt sulfotransferase SULT2A1 0.0025
1385 Angiotensin-converting enzyme 2 ACE2 0.0025
4252 Penicillin-binding protein 5 dacA 0.0025
229 Retinoic acid receptor beta RARB 0.0025
1714 Mitogen-activated protein kinase 3 MAPK3 0.0025
780 Retinoic acid receptor RXR-gamma RXRG 0.0025
357 Carbonic anhydrase 2 CA2 0.0025
185 Vasopressin V1a receptor AVPR1A 0.0024
730 Retinoic acid receptor alpha RARA 0.0024
1596 Protein-glutamine gamma-glutamyltransferase 2 TGM2 0.0024
3616 Fatty acid-binding protein, epidermal FABP5 0.0024
5431 Lipid binding protein Not Available 0.0024
5433 UPF0230 protein TM_1468 TM_1468 0.0024
5430 Hepatocyte nuclear factor 4-gamma HNF4G 0.0024
319 Opioid receptor, sigma 1 OPRS1 0.0024
159 Penicillin-binding protein 2B penA 0.0024
6121 Penicillin-binding protein 2B penA 0.0024
322 Vasopressin V2 receptor AVPR2 0.0024
1618 High affinity nerve growth factor receptor NTRK1 0.0024
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0024
6231 Pepsin A PGA3 0.0024
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0024
6459 Glycodelin PAEP 0.0024
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0024
6 Coagulation factor XIII A chain F13A1 0.0024
4103 Proteasome subunit beta type 2 PSMB2 0.0023
4102 Proteasome subunit beta type 5 PSMB5 0.0023
4101 Proteasome subunit beta type 1 PSMB1 0.0023
4221 Vascular endothelial growth factor VEGF 0.0023
5816 Cadherin-5 CDH5 0.0023
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0023
713 Sodium-dependent dopamine transporter SLC6A3 0.0023
88 Retinoic acid receptor RXR-beta RXRB 0.0023
162 Retinoic acid receptor gamma-1 RARG 0.0023
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0023
624 Guanidinoacetate N-methyltransferase GAMT 0.0022
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0022
1507 Cytochrome c CYCS 0.0022
6103 Arylamine N-acetyltransferase 1 NAT1 0.0022
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0022
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0022
4058 Glycine N-acyltransferase-like protein 2 GLYATL2 0.0022
4057 Glycine N-acyltransferase GLYAT 0.0022
4059 Glycine N-acyltransferase-like protein 1 GLYATL1 0.0022
4056 N-arachidonyl glycine receptor GPR18 0.0022
4061 Peroxisomal sarcosine oxidase PIPOX 0.0022
4055 Bile acid CoA:amino acid N-acyltransferase BAAT 0.0022
1236 Sodium- and chloride-dependent glycine transporter 1 SLC6A9 0.0022
4062 Sodium- and chloride-dependent glycine transporter 2 SLC6A5 0.0022
4060 Vesicular inhibitory amino acid transporter SLC32A1 0.0022
1088 5-aminolevulinate synthase, erythroid-specific, mitochondrial ALAS2 0.0022
1466 Glycyl-tRNA synthetase GARS 0.0022
494 Caspase-1 CASP1 0.0022
3014 Ribonuclease UK114 HRSP12 0.0022
3718 Hydrogen peroxide-inducible genes activator oxyR 0.0022
3617 Non-heme chloroperoxidase cpo 0.0022
5426 Non-heme chloroperoxidase cpo 0.0022
5428 Replication protein repA 0.0022
5427 Hydroxyquinol 1,2-dioxygenase chqB 0.0022
3018 HTH-type transcriptional regulator malT malT 0.0022
3830 Calreticulin CALR 0.0022
760 Fibroblast growth factor 1 FGF1 0.0022
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0021
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0021
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0021
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0021
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0021
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0021
2207 Rhodopsin RHO 0.0021
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0021
331 Retinol-binding protein I, cellular RBP1 0.0021
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0021
3978 Adenylosuccinate synthetase isozyme 1 ADSSL1 0.0021
283 SEC14-like protein 2 SEC14L2 0.002
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.002
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.002
2339 Protein-glutamine gamma-glutamyltransferase E TGM3 0.002
6755 Poliovirus receptor PVR 0.002
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.002
6034 Hydroxyindole O-methyltransferase ASMT 0.002
6035 Nuclear receptor ROR-beta RORB 0.002
6036 Eosinophil peroxidase EPX 0.002
2107 Microtubule-associated protein 1A MAP1A 0.002
1992 Vitamin D-binding protein GC 0.002
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.002
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0019
2958 Probable tautomerase ydcE pptA 0.0019
2573 Cocaine esterase cocE 0.0019
7263 Cocaine esterase Not Available 0.0019
1638 Solute carrier family 2, facilitated glucose transporter member 2 SLC2A2 0.0019
239 Coagulation factor X F10 0.0019
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0019
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0019
3115 Ras-related protein Rab-9 RAB9A 0.0019
3603 Chlorocatechol 1,2-dioxygenase clcA 0.0018
2077 Caspase-3 CASP3 0.0018
3312 Fatty acid-binding protein, brain FABP7 0.0018
84 Nuclear receptor 0B1 NR0B1 0.0018
267 Plasminogen activator inhibitor 1 SERPINE1 0.0017
4054 Glycine cleavage system H protein, mitochondrial GCSH 0.0017
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0017
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0017
528 5-hydroxytryptamine 1E receptor HTR1E 0.0017
455 5-aminolevulinate synthase, nonspecific, mitochondrial ALAS1 0.0017
575 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial GCAT 0.0017
681 Glycine dehydrogenase [decarboxylating], mitochondrial GLDC 0.0017
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0017
62 Glycine receptor subunit beta GLRB 0.0017
605 Fumarate reductase flavoprotein subunit frdA 0.0016
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0016
3673 Fumarate reductase flavoprotein subunit fccA 0.0016
4912 Fumarate reductase flavoprotein subunit ifcA 0.0016
6549 Fumarate reductase flavoprotein subunit frdA 0.0016
571 Melatonin receptor type 1A MTNR1A 0.0016
362 Melatonin receptor type 1B MTNR1B 0.0016
6824 Tyrosine-protein kinase Lyn LYN 0.0016
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0016
6766 O-GlcNAcase BT_4395 BT_4395 0.0016
383 Glycine amidinotransferase, mitochondrial GATM 0.0016
6221 Steroid hormone receptor ERR1 ESRRA 0.0016
5300 Antigen peptide transporter 1 TAP1 0.0016
2599 Tyrosine-protein kinase HCK HCK 0.0016
411 Glycine N-methyltransferase GNMT 0.0016
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0016
2297 Genome polyprotein Not Available 0.0016
2322 Genome polyprotein Not Available 0.0016
2694 Genome polyprotein Not Available 0.0016
2719 Genome polyprotein Not Available 0.0016
2860 Genome polyprotein Not Available 0.0016
2928 Genome polyprotein Not Available 0.0016
3160 Genome polyprotein Not Available 0.0016
3260 Genome polyprotein Not Available 0.0016
4783 Genome polyprotein Not Available 0.0016
5726 Genome polyprotein Not Available 0.0016
5779 Genome polyprotein Not Available 0.0016
5867 Genome polyprotein Not Available 0.0016
6253 Genome polyprotein Not Available 0.0016
6301 Genome polyprotein Not Available 0.0016
6380 Genome polyprotein Not Available 0.0016
6381 Genome polyprotein Not Available 0.0016
6437 Genome polyprotein Not Available 0.0016
6520 Genome polyprotein Not Available 0.0016
6521 Genome polyprotein Not Available 0.0016
6652 Genome polyprotein Not Available 0.0016
6734 Genome polyprotein Not Available 0.0016
6735 Genome polyprotein Not Available 0.0016
6736 Genome polyprotein Not Available 0.0016
6737 Genome polyprotein Not Available 0.0016
6738 Genome polyprotein Not Available 0.0016
6739 Genome polyprotein Not Available 0.0016
6744 Genome polyprotein Not Available 0.0016
6748 Genome polyprotein Not Available 0.0016
6894 Genome polyprotein Not Available 0.0016
6898 Genome polyprotein Not Available 0.0016
3884 SHMT2 protein SHMT2 0.0015
3901 SHMT2 protein SHMT2 0.0015
3885 Hypothetical protein DKFZp686P09201 DKFZp686P09201 0.0015
3879 Serine hydroxymethyltransferase 2 Not Available 0.0015
321 Serine hydroxymethyltransferase, mitochondrial SHMT2 0.0015
702 UMP-CMP kinase CMPK1 0.0015
165 FL cytokine receptor FLT3 0.0015
1770 Phospholipase C PLCL1 0.0015
2841 Phospholipase C plc 0.0015
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0015
1178 Adenosine A2a receptor ADORA2A 0.0014
2693 Heat-labile enterotoxin B chain eltB 0.0014
4674 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase cumD 0.0014
2129 Sucrase-isomaltase, intestinal SI 0.0014
1629 Transcription factor AP-1 JUN 0.0014
233 Potassium channel subfamily K member 2 KCNK2 0.0014
1864 RET proto-oncogene RET 0.0014
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0014
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0014
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0014
820 Glycine receptor subunit alpha-2 GLRA2 0.0014
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0014
367 Serine hydroxymethyltransferase, cytosolic SHMT1 0.0014
1039 Histone deacetylase 9 HDAC9 0.0013
4010 Mitochondrial dicarboxylate carrier SLC25A10 0.0013
1410 Oxidoreductase HSD17B6 0.0013
4725 Oxidoreductase Not Available 0.0013
5124 Oxidoreductase Not Available 0.0013
4007 Succinate receptor 1 SUCNR1 0.0013
4008 Succinyl-CoA:3-ketoacid-coenzyme A transferase 2, mitochondrial OXCT2 0.0013
4002 Succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial SUCLG1 0.0013
673 Solute carrier family 13 member 3 SLC13A3 0.0013
391 Succinyl-CoA ligase [GDP-forming] beta-chain, mitochondrial SUCLG2 0.0013
4009 Succinyl-CoA ligase [ADP-forming] beta-chain, mitochondrial SUCLA2 0.0013
498 Solute carrier family 13 member 2 SLC13A2 0.0013
25 Solute carrier family 13 member 1 SLC13A1 0.0013
4773 Deoxycytidine kinase DCK 0.0012
822 Aldose reductase AKR1B1 0.0012
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0012
694 Matrix protein 2 M 0.0012
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0012
4226 Uridine phosphorylase 2 UPP2 0.0012
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0012
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0012
4003 Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial OXCT1 0.0012
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.0012
6859 Protein S100-A4 S100A4 0.0012
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0011
2112 Toll-like receptor 9 TLR9 0.0011
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0011
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0011
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0011
4225 Uridine phosphorylase 1 UPP1 0.0011
1256 5-hydroxytryptamine 6 receptor HTR6 0.0011
3940 Gamma-butyrobetaine dioxygenase BBOX1 0.0011
97 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 PLOD1 0.0011
3938 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 PLOD3 0.0011
3964 Trimethyllysine dioxygenase, mitochondrial TMLHE 0.0011
4006 Succinate dehydrogenase cytochrome b560 subunit, mitochondrial SDHC 0.0011
4001 Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial SDHB 0.0011
131 Synaptic vesicular amine transporter SLC18A2 0.0011
427 Substance-P receptor TACR1 0.0011
4023 N-acetylglutamate synthase, mitochondrial NAGS 0.0011
4024 Mitochondrial glutamate carrier 2 SLC25A18 0.0011
4025 Mitochondrial glutamate carrier 1 SLC25A22 0.0011
4021 Probable glutamyl-tRNA synthetase, mitochondrial EARS2 0.0011
664 Glutamate decarboxylase 2 GAD2 0.0011
3890 Glutamate decarboxylase 2 GAD2 0.0011
4026 Aspartyl aminopeptidase DNPEP 0.0011
4022 Glutamate--ammonia ligase domain-containing protein 1 LGSN 0.0011
1912 Excitatory amino acid transporter 1 SLC1A3 0.0011
4016 Excitatory amino acid transporter 5 SLC1A7 0.0011
4019 Excitatory amino acid transporter 4 SLC1A6 0.0011
4017 5-oxoprolinase OPLAH 0.0011
1047 Excitatory amino acid transporter 2 SLC1A2 0.0011
926 Metabotropic glutamate receptor 7 GRM7 0.0011
920 Glutamate receptor, ionotropic kainate 5 GRIK5 0.0011
4018 Glutamate receptor delta-2 subunit GRID2 0.0011
915 Delta 1-pyrroline-5-carboxylate synthetase ALDH18A1 0.0011
922 Glutamate receptor 4 GRIA4 0.0011
927 Metabotropic glutamate receptor 8 GRM8 0.0011
925 Metabotropic glutamate receptor 4 GRM4 0.0011
924 Glutamate receptor, ionotropic kainate 3 GRIK3 0.0011
919 Glutamate receptor, ionotropic kainate 4 GRIK4 0.0011
4020 Glutamyl aminopeptidase ENPEP 0.0011
4027 Glutamate receptor delta-1 subunit GRID1 0.0011
144 Hemoglobin subunit alpha HBA1 0.001
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.001
6100 BDNF/NT-3 growth factors receptor NTRK2 0.001
106 Cannabinoid receptor 2 CNR2 0.001
6174 50S ribosomal protein L32 rpmF 0.001
4203 Histamine N-methyltransferase HNMT 0.001
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.001
3999 Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial SDHD 0.001
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.001
197 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial SDHA 0.001
2473 Tyrosine-protein kinase CSK CSK 0.001
2398 Tyrosine-protein kinase ZAP-70 ZAP70 0.001
476 RAC-alpha serine/threonine-protein kinase AKT1 0.001
723 Cytosolic phospholipase A2 PLA2G4A 0.001
68 Cannabinoid receptor 1 CNR1 0.001
4192 DNA topoisomerase 2-beta TOP2B 0.001
3957 Adenosine deaminase ADA 0.0009
936 Ephrin type-A receptor 2 EPHA2 0.0009
3611 Cytidine deaminase cdd 0.0009
3707 Cytidine deaminase cdd 0.0009
4211 Cytidine deaminase CDA 0.0009
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0009
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0009
360 Ribonucleoside-diphosphate reductase large subunit RRM1 0.0009
1569 G1/S-specific cyclin-D1 CCND1 0.0009
2240 Cell division protein kinase 2 CDK2 0.0009
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0009
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0009
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0009
625 Glutamate carboxypeptidase 2 FOLH1 0.0009
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0009
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0009
54 Prothrombin F2 0.0009
1268 Neuropeptide S receptor NPSR1 0.0009
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0009
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0009
1262 Corticotropin-lipotropin POMC 0.0009
3639 Thymidine phosphorylase deoA 0.0008
3936 Thymidine phosphorylase TYMP 0.0008
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0008
665 Phosphoserine aminotransferase PSAT1 0.0008
4652 Phosphoserine aminotransferase serC 0.0008
801 Kynurenine/alpha-aminoadipate aminotransferase mitochondrial AADAT 0.0008
3895 Kynurenine--oxoglutarate transaminase 3 CCBL2 0.0008
420 Glutamate decarboxylase 1 GAD1 0.0008
3900 Glutamate decarboxylase 1 GAD1 0.0008
823 Fibroblast growth factor receptor 2 FGFR2 0.0008
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0008
6211 Tubulin epsilon chain TUBE1 0.0008
6212 Tubulin gamma-1 chain TUBG1 0.0008
6210 Tubulin delta chain TUBD1 0.0008
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0008
484 Tyrosine-protein kinase ABL2 ABL2 0.0008
916 Metabotropic glutamate receptor 1 GRM1 0.0008
3937 Fatty-acid amide hydrolase FAAH 0.0008
923 Glutamate receptor 3 GRIA3 0.0008
908 Glutathione S-transferase theta-1 GSTT1 0.0008
6073 Potassium channel subfamily K member 9 KCNK9 0.0008
6072 Potassium channel subfamily K member 3 KCNK3 0.0008
2530 Protein kinase C theta type PRKCQ 0.0008
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0008
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0008
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0008
914 Formimidoyltransferase-cyclodeaminase FTCD 0.0007
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0007
6316 ADP-ribosylation factor 1 ARF1 0.0007
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0007
2408 Tyrosine-protein kinase SYK SYK 0.0007
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0007
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.0007
6837 Serine/threonine-protein kinase 17B STK17B 0.0007
921 Glutamate receptor 2 GRIA2 0.0007
1374 Natriuretic peptides B NPPB 0.0006
1827 Gap junction alpha-1 protein GJA1 0.0006
1908 Vascular cell adhesion protein 1 VCAM1 0.0006
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0006
2216 Fibroblast growth factor receptor 4 FGFR4 0.0006
1063 Signal transducer and activator of transcription 5B STAT5B 0.0006
3221 Cytochrome c4 cc4 0.0006
814 Ryanodine receptor 1 RYR1 0.0006
1176 Mitogen-activated protein kinase 1 MAPK1 0.0006
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.0006
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0006
174 Sigma 1-type opioid receptor SIGMAR1 0.0006
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0006
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0006
6048 Troponin C, skeletal muscle TNNC2 0.0006
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0006
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0005
1721 Glycogen synthase kinase-3 beta GSK3B 0.0005
3238 Multidrug resistance protein mexA mexA 0.0005
3116 Bacterioferritin bfr 0.0005
4906 Bacterioferritin bfr 0.0005
4965 Bacterioferritin bfr 0.0005
3173 Enolase eno 0.0005
3709 Glycerol uptake facilitator protein glpF 0.0005
3336 C4-dicarboxylate transport transcriptional regulatory protein dctD dctD 0.0005
3393 TGF-beta receptor type-2 TGFBR2 0.0005
5489 Ribonucleoside-diphosphate reductase 1 subunit beta nrdB 0.0005
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0005
6743 Non-fluorescent flavoprotein luxF 0.0005
6753 Apolipoprotein M APOM 0.0005
2528 Fatty acid metabolism regulator protein fadR 0.0005
6740 Fatty acid metabolism regulator protein fadR 0.0005
6752 Guanylyl cyclase-activating protein 1 GUCA1A 0.0005
394 Calcineurin subunit B isoform 1 PPP3R1 0.0005
6742 Recoverin RCVRN 0.0005
6747 Chalcone/stilbene synthase family protein MT1417 0.0005
6741 Peroxisomal 3,2-trans-enoyl-CoA isomerase PECI 0.0005
6522 Hepatocyte nuclear factor 4-alpha HNF4A 0.0005
6751 Gag polyprotein gag 0.0005
6746 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA 0.0005
6749 Polyprotein Not Available 0.0005
5798 Mitogen-activated protein kinase 11 MAPK11 0.0005
16 Adenosine A1 receptor ADORA1 0.0005
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0005
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0005
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0005
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0005
2852 DNA mismatch repair protein mutL mutL 0.0005
5961 Insulin INS 0.0005
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0005
6527 Lymphocyte antigen 96 LY96 0.0005
3191 Histidinol dehydrogenase hisD 0.0005
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0004
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0004
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0004
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0004
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0004
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0004
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0004
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0004
4311 tRNA TRDMT1 0.0004
4325 tRNA trmD 0.0004
4328 tRNA trmD 0.0004
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0004
6750 ADP-ribosylation factor 6 ARF6 0.0004
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0004
4692 A/G-specific adenine glycosylase mutY 0.0004
6524 Protein tonB tonB 0.0004
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0004
1360 Sphingomyelin phosphodiesterase SMPD1 0.0004
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0004
2435 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0004
6613 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0004
6163 Copper-transporting ATPase 2 ATP7B 0.0004
6165 Copper-transporting ATPase 1 ATP7A 0.0004
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0004
2802 Endoglucanase G celCCG 0.0004
340 Apoptotic protease-activating factor 1 APAF1 0.0004
6146 High affinity copper uptake protein 1 SLC31A1 0.0004
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0004
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0004
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0004
76 Nitric-oxide synthase, brain NOS1 0.0004
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0004
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0004
444 Alcohol dehydrogenase 1B ADH1B 0.0003
864 Gag-Pol polyprotein gag-pol 0.0003
2237 Gag-Pol polyprotein gag-pol 0.0003
2326 Gag-Pol polyprotein gag-pol 0.0003
2451 Gag-Pol polyprotein gag-pol 0.0003
2901 Gag-Pol polyprotein gag-pol 0.0003
3165 Gag-Pol polyprotein gag-pol 0.0003
3722 Gag-Pol polyprotein gag-pol 0.0003
6306 Gag-Pol polyprotein gag-pol 0.0003
6624 Gag-Pol polyprotein gag-pol 0.0003
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0003
825 Arsenical pump-driving ATPase ASNA1 0.0003
3435 Arsenical pump-driving ATPase arsA 0.0003
486 Serine/threonine-protein kinase ALS2CR7 CDK15 0.0003
2105 ATP-binding cassette sub-family G member 1 ABCG1 0.0003
377 Beta-adrenergic receptor kinase 1 ADRBK1 0.0003
510 Serine/threonine-protein kinase receptor R3 ACVRL1 0.0003
733 Activin receptor type 1B ACVR1B 0.0003
225 NEDD8-activating enzyme E1 regulatory subunit NAE1 0.0003
745 Anti-Muellerian hormone type-2 receptor AMHR2 0.0003
483 A-Raf proto-oncogene serine/threonine-protein kinase ARAF 0.0003
21 Beta-adrenergic receptor kinase 2 ADRBK2 0.0003
154 AFG3-like protein 2 AFG3L2 0.0003
395 ALK tyrosine kinase receptor Not Available 0.0003
896 Glutathione S-transferase Mu 1 GSTM1 0.0003
295 Carbonic anhydrase 1 CA1 0.0003
292 Activin receptor type-1 ACVR1 0.0003
849 Activated CDC42 kinase 1 TNK2 0.0003
4943 Cytochrome c6 petJ 0.0003
4954 Soluble cytochrome b558 Not Available 0.0003
4942 Diheme cytochrome c napB napB 0.0003
5000 HemO hemO 0.0003
4916 Cyanoglobin glbN 0.0003
4981 Iron-starvation protein PigA pigA 0.0003
4994 Hemoglobin-like protein HbO glbO 0.0003
4947 Bacterial hemoglobin vhb 0.0003
4975 Cytochrome c-556 RPA3973 0.0003
4935 Cytochrome c-554 cycA1 0.0003
4984 Neuroglobin NGB 0.0003
4934 Cytochrome c-551 nirM 0.0003
5218 Cytochrome c-551 nirM 0.0003
4961 Hemophore HasA hasA 0.0003
4905 Cytochrome c2 Not Available 0.0003
4939 Cytochrome c2 cycA 0.0003
4964 Cytochrome c2 cycA 0.0003
4979 Cytochrome c2 cycA 0.0003
6673 Cytochrome c2 cycA 0.0003
4910 Cytoglobin CYGB 0.0003
4936 Cytochrome c2 iso-2 Not Available 0.0003
4909 CooA protein cooA 0.0003
4915 Cytochrome c-550 psbV 0.0003
4959 Cytochrome c-550 psbV 0.0003
5216 Cytochrome c-550 psbV 0.0003
4925 Cytochrome c-type protein SHP shp 0.0003
4998 Hemoglobin-like protein yjbI yjbI 0.0003
4937 Cytochrome oxidase subunit II rcoxA 0.0003
644 Heme oxygenase 2 HMOX2 0.0003
4982 Heme oxygenase 2 pbsA2 0.0003
4903 Methyl-accepting chemotaxis protein Tar4 0.0003
4931 Cytochrome P450 167A1 CYP167A1 0.0003
4971 Nonaheme cytochrome c hmcA 0.0003
4989 Cytochrome c551 peroxidase ccp 0.0003
5222 Cytochrome c551 peroxidase ccpA 0.0003
4976 Apocytochrome f petA 0.0003
6407 Apocytochrome f petA 0.0003
4904 Cytochrome c family protein GSU1996 0.0003
4907 Cytochrome c-L moxG 0.0003
6865 Cytochrome c-L moxG 0.0003
4999 Cytochrome P450 165B3 CYP165B3 0.0003
4972 P450cin cinA 0.0003
4764 Cytochrome P450 165C4 CYP165C4 0.0003
4960 Putative cytochrome P450-family protein SCO7417 0.0003
4926 Heme-based aerotactic transducer hemAT hemAT 0.0003
4922 Cytochrome c, putative SO_4144 0.0003
4952 Catalase/peroxidase katA 0.0003
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0003
4993 Hydroxylamine oxidoreductase hao1 0.0003
3093 Catalase HPII katE 0.0003
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0003
2427 Ferrichrome-iron receptor fhuA 0.0003
704 Long-chain-fatty-acid--CoA ligase 1 ACSL1 0.0003
821 Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 0.0003
386 Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 0.0003
297 Adenylate cyclase type 1 ADCY1 0.0003
289 Cytosolic purine 5'-nucleotidase NT5C2 0.0003
6264 cAMP-dependent protein kinase inhibitor alpha PKIA 0.0003
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0003
164 Histamine H4 receptor HRH4 0.0003
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0003
661 ADP/ATP translocase 1 SLC25A4 0.0002
6021 Adenosine kinase ADK 0.0002
4920 Peroxidase/catalase katG 0.0002
4923 Cytochrome c3 DvMF_2499 0.0002
4945 Cytochrome c3 Not Available 0.0002
4949 Cytochrome c3 DVU_3171 0.0002
4968 Cytochrome c3 cytc3 0.0002
4997 Cytochrome c3 SO_2727 0.0002
5219 Cytochrome c3 cyd 0.0002
2119 Cytochrome b5 CYB5A 0.0002
4948 Cytochrome c-553 Not Available 0.0002
4902 Nine-heme cytochrome c Ddes_2038 0.0002
3189 High-molecular-weight cytochrome c hmcA 0.0002
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0002
4990 PpcA ppcA 0.0002
4037 Hypothetical protein GPX1 0.0002
4297 Hypothetical protein SP_1951 0.0002
4521 Hypothetical protein BC_2969 0.0002
4540 Hypothetical protein TM_1070 0.0002
4555 Hypothetical protein MT1739 0.0002
4569 Hypothetical protein mshD 0.0002
4578 Hypothetical protein PA3270 0.0002
4747 Hypothetical protein PA3967 0.0002
5177 Hypothetical protein TM_0096 0.0002
5194 Hypothetical protein PA1204 0.0002
5240 Hypothetical protein Rv2991 0.0002
5370 Hypothetical protein TM_1158 0.0002
5710 Hypothetical protein Tb927.5.1360 0.0002
4988 Sulfite oxidase, mitochondrial SUOX 0.0002
3375 Acidic cytochrome c3 Not Available 0.0002
3570 Cytochrome P450 152A1 cypC 0.0002
4289 Cytochrome P450 TT_P0059 0.0002
6262 Cytochrome P450 staP 0.0002
4992 Cytochrome c peroxidase Not Available 0.0002
2915 Sensor protein fixL fixL 0.0002
4944 Sensor protein fixL fixL 0.0002
4813 Heme oxygenase hmuO 0.0002
5769 Heme oxygenase Not Available 0.0002
4385 Cytochrome c' Not Available 0.0002
4967 Cytochrome c' cycA 0.0002
5038 Cytochrome c' Not Available 0.0002
5223 Cytochrome c' cycP 0.0002
2230 Catalase CAT 0.0002
3249 Catalase katA 0.0002
3625 Catalase katA 0.0002
4539 Catalase katA 0.0002
4941 Catalase katB 0.0002
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0002
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0002
3670 Soluble cytochrome b562 precursor cybC 0.0002
3411 Cytochrome P450 121 cyp121 0.0002
2617 Nitric oxide synthase oxygenase nos 0.0002
2701 Nitric oxide synthase oxygenase nos 0.0002
3291 Cytochrome c-552 cycA 0.0002
4927 Cytochrome c-552 nrfA 0.0002
4938 Cytochrome c-552 cycA 0.0002
4953 Cytochrome c-552 nrfA 0.0002
5217 Cytochrome c-552 cycM 0.0002
3102 Flavohemoprotein hmp 0.0002
4969 Flavohemoprotein hmp 0.0002
4386 Hemoglobin-like protein HbN glbN 0.0002
518 Peroxidase/catalase T katG 0.0002
3127 Nitrite reductase nirS 0.0002
3284 Nitrite reductase nirS 0.0002
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0002
2972 6-deoxyerythronolide B hydroxylase eryF 0.0002
4608 Putative cytochrome P450 SCO1207 0.0002
4963 Putative cytochrome P450 SCO2884 0.0002
6254 Putative cytochrome P450 SCO6998 0.0002
693 Hemoglobin subunit beta HBB 0.0001
6268 Hydroxyacid oxidase 1 HAO1 0.0001
810 Heme oxygenase 1 HMOX1 0.0001
3391 Heme oxygenase 1 pbsA1 0.0001
2298 Cytochrome P450-cam camC 0.0001
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