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Phenylalanyl-tRNA synthetase alpha chain


Partner ID 6602
Name Phenylalanyl-tRNA synthetase alpha chain
Synonyms 104
Gene name pheS
General function Translation, ribosomal structure and biogenesis
Specific function ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe)
Gene sequence + ...

ATGTCAGAACAAGAAATTTGGAAAAAAGTATTAGAAGTTGCTGAATCAGAAATATCTAAATCGACATTTAATACTTTTTTGAAAGATACAGAACTCAAAGAAATTCGTGATAATGTTGCAATCATCTTTGTAATTCATGAATTTTACGCAGAATGGTTAAATTCAAACTACAAAGAAGTAATCCAAACAATTATGAAAGATGTTATTGGTTATGAAGTTGAACCCAAATTTTTCACTGCTGAACAATTAGCTGAACTTGATGAGACAAGTCGTAAATCTAACACGCCAAGCGAACCTCAACGTCAAATCATTGAATATGGTCATGAAGGCACAGATCAATTCAATACTCACAATACATTTGATACTTTCGTCATTGGACCTGGCAATAGATTTCCACACGCAGCAAGTCTTGCAGTTGCTGAAGCACCAGCACAAGCATACAACCCTCTATTTATATATGGTGGCGTTGGTCTTGGTAAGACACATCTTATGCATGCGATCGGTCATCATGTTCTTAGCAATCAACCAAATGCTAAAGTACTATATACTTCAAGTGAAAAATTCACAAATGACTTCATCAAATCAATTCGTAACAATGAACCTGAAGCCTTTAGAGAAAAGTATAGAAACATCGACGTGTTACTGATTGATGACATTCAATTTATTCAGAATAAAGAACAAACGCAAGAAGAGTTCTTCCATACATTTAATGAATTACATCAAAATAAGAAGCAAATTGTCATTTCAAGTGACCGTCCACCTAAAGAAATTGCAAAATTAGAAGACCGTTTACGTTCTCGTTTCGAATGGGGATTAATCGTTGATATTACTCCTCCTGACTATGAAACACGTATGGCGATTCTTCAGAAAAAAATCGAAGAAGAGAATTTAGAAATTCCTGCTGAAGCTTTAAATTATATTGCTAATCAAATTCAATCAAACATCCGTGAATTAGAAGGCGCACTCACACGTTTGCTTGCCTATTCTAAACTTCAAGGCAGACCTATTACGACTGAATTAGCGGCAGAAGCGCTCAAAGATATTATTCAAGTTCCTAAATCTAAAAAAATTACAATCCAAGATATTCAAAAAGTCGTTGGACACTACTACAACGTTCGCATCGAAGATTTCAGCGCAAAAAAACGTACAAAATCAATTGCTTATCCACGTCAAATTGCGATGTATTTATCAAGAGAACTTACCGATTTTTCATTACCTAAGATTGGTGAAGAATTCGGTGGTCGAGATCATACGACAGTGATTCATGCGCACGAAAAGATTGCTAAAGATATTAAAGCCGATACAATTTTTAAACAAGAAGTTGAAGATTTGGAAAAAGAAATTCGCAATCAATAA
Protein sequence + ...

MTQNDSMAELKQQALVDINEAQNERELQDVKVKYLGKKGSVSGLMKNMKDLPNEEKPAYGQKVNELRQTIQKELDEKQELLKNEKLNQQLAEETIDVTLPSRQISIGSKHPLTRTVEEIEDLFLGLGYEIVDGYEVEQDYYNFEALNLPKSHPARDMQDSFYITDEILMRTHTSPVQARTMEKRNGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGLVVDKNIKMSDLKGTLELVAKKLFGADREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCNVCKHTGWIEILGAGMVHPNVLEMAGFDSNEYSGFAFGMGPDRIAMLKYGIEDIRYFYTNDVRFLEQFKAVEDRGEA
GO Classification
component
intracellular
cytoplasm
cell
function
ATP binding
binding
ligase activity
ligase activity, forming phosphoric ester bonds
nucleotide binding
RNA ligase activity
catalytic activity
tRNA ligase activity
phenylalanine-tRNA ligase activity
purine nucleotide binding
adenyl nucleotide binding
process
phenylalanyl-tRNA aminoacylation
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
physiological process
metabolism
cellular metabolism
RNA metabolism
tRNA metabolism
tRNA aminoacylation
tRNA aminoacylation for protein translation
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB07817 1-{3-[(4-pyridin-2-ylpiperazin-1-yl)sulfonyl]phenyl}-3-(1,3-thiazol-2-yl)urea

Associated as Prediction

Id Name
DB00114 Pyridoxal Phosphate
DB00117 L-Histidine
DB00119 Pyruvic acid
DB00120 L-Phenylalanine
DB00123 L-Lysine
DB00125 L-Arginine
DB00128 L-Aspartic Acid
DB00130 L-Glutamine
DB00133 L-Serine
DB00134 L-Methionine
DB00135 L-Tyrosine
DB00138 L-Cystine
DB00142 L-Glutamic Acid
DB00145 Glycine
DB00149 L-Leucine
DB00150 L-Tryptophan
DB00151 L-Cysteine
DB00156 L-Threonine
DB00160 L-Alanine
DB00161 L-Valine
DB00167 L-Isoleucine
DB00172 L-Proline
DB00174 L-Asparagine
DB00279 Liothyronine
DB00360 Tetrahydrobiopterin
DB00368 Norepinephrine
DB00668 Epinephrine
DB00765 Metyrosine
DB01235 Levodopa
DB01583 Liotrix
DB01746 D-Leucine
DB01786 D-Alanine
DB02556 D-Phenylalanine
DB02562 Quinonoid 7,8-Tetrahydrobiopterin
DB02692 (6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin
DB02750 S-(Methylmercury)-L-Cysteine
DB02952 Alpha-Aminoisobutyric Acid
DB03107 Beta-Alanine
DB03225 D-Tryptophan
DB03552 Meta-Tyrosine
DB03673 Beta(2-Thienyl)Alanine
DB03839 D-Tyrosine
DB03929 D-Serine
DB04398 Lactic Acid
DB04400 7,8-Dihydrobiopterin
DB04419 Norleucine
DB06262 Droxidopa
DB07817 1-{3-[(4-pyridin-2-ylpiperazin-1-yl)sulfonyl]phenyl}-3-(1,3-thiazol-2-yl)urea
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