DT-Web

DB04398 - Lactic Acid


Identification
Name Lactic Acid
Accession Number DB04398 (EXPT01996)
Type small molecule
Description A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 90.0779
Groups experimental
Monoisotopic Weight 90.031694058
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Bifunctional protein putA [Includes: Proline dehydrogenase
Name Bifunctional protein putA [Includes: Proline dehydrogenase
Gene Name putA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.6873
NimA-related protein
Name NimA-related protein
Gene Name DR_0842
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.4539

Transporters


Monocarboxylate transporter 2
Name Monocarboxylate transporter 2
Gene Name SLC16A7
Actions substrate,inhibitor
References
  • Lin RY, Vera JC, Chaganti RS, Golde DW: Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter. J Biol Chem. 1998 Oct 30;273(44):28959-65. - Pubmed
  • Broer S, Broer A, Schneider HP, Stegen C, Halestrap AP, Deitmer JW: Characterization of the high-affinity monocarboxylate transporter MCT2 in Xenopus laevis oocytes. Biochem J. 1999 Aug 1;341 ( Pt 3):529-35. - Pubmed
DTHybrid score 0.7591
Solute carrier organic anion transporter family member 2B1
Name Solute carrier organic anion transporter family member 2B1
Gene Name SLCO2B1
Actions substrate,inhibitor
References
  • Kobayashi D, Nozawa T, Imai K, Nezu J, Tsuji A, Tamai I: Involvement of human organic anion transporting polypeptide OATP-B (SLC21A9) in pH-dependent transport across intestinal apical membrane. J Pharmacol Exp Ther. 2003 Aug;306(2):703-8. Epub 2003 Apr 30. - Pubmed
  • Nozawa T, Imai K, Nezu J, Tsuji A, Tamai I: Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human. J Pharmacol Exp Ther. 2004 Feb;308(2):438-45. Epub 2003 Nov 10. - Pubmed
DTHybrid score 0.4092
Monocarboxylate transporter 1
Name Monocarboxylate transporter 1
Gene Name SLC16A1
Actions substrate,inhibitor
References
  • Lin RY, Vera JC, Chaganti RS, Golde DW: Human monocarboxylate transporter 2 (MCT2) is a high affinity pyruvate transporter. J Biol Chem. 1998 Oct 30;273(44):28959-65. - Pubmed
  • Broer S, Schneider HP, Broer A, Rahman B, Hamprecht B, Deitmer JW: Characterization of the monocarboxylate transporter 1 expressed in Xenopus laevis oocytes by changes in cytosolic pH. Biochem J. 1998 Jul 1;333 ( Pt 1):167-74. - Pubmed
  • Broer S, Rahman B, Pellegri G, Pellerin L, Martin JL, Verleysdonk S, Hamprecht B, Magistretti PJ: Comparison of lactate transport in astroglial cells and monocarboxylate transporter 1 (MCT 1) expressing Xenopus laevis oocytes. Expression of two different monocarboxylate transporters in astroglial cells and neurons. J Biol Chem. 1997 Nov 28;272(48):30096-102. - Pubmed
  • Tamai I, Sai Y, Ono A, Kido Y, Yabuuchi H, Takanaga H, Satoh E, Ogihara T, Amano O, Izeki S, Tsuji A: Immunohistochemical and functional characterization of pH-dependent intestinal absorption of weak organic acids by the monocarboxylic acid transporter MCT1. J Pharm Pharmacol. 1999 Oct;51(10):1113-21. - Pubmed
  • Takanaga H, Tamai I, Inaba S, Sai Y, Higashida H, Yamamoto H, Tsuji A: cDNA cloning and functional characterization of rat intestinal monocarboxylate transporter. Biochem Biophys Res Commun. 1995 Dec 5;217(1):370-7. - Pubmed
DTHybrid score 0.715
Monocarboxylate transporter 10
Name Monocarboxylate transporter 10
Gene Name SLC16A10
Actions substrate,inhibitor
References
  • Kim DK, Kanai Y, Chairoungdua A, Matsuo H, Cha SH, Endou H: Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters. J Biol Chem. 2001 May 18;276(20):17221-8. Epub 2001 Feb 20. - Pubmed
  • Kim DK, Kanai Y, Matsuo H, Kim JY, Chairoungdua A, Kobayashi Y, Enomoto A, Cha SH, Goya T, Endou H: The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location. Genomics. 2002 Jan;79(1):95-103. - Pubmed
DTHybrid score 0.4847
Solute carrier organic anion transporter family member 2A1
Name Solute carrier organic anion transporter family member 2A1
Gene Name SLCO2A1
Actions inhibitor
References
  • Chan BS, Endo S, Kanai N, Schuster VL: Identification of lactate as a driving force for prostanoid transport by prostaglandin transporter PGT. Am J Physiol Renal Physiol. 2002 Jun;282(6):F1097-102. - Pubmed
DTHybrid score 0.4501
Monocarboxylate transporter 4
Name Monocarboxylate transporter 4
Gene Name SLC16A3
Actions substrate
References
  • Manning Fox JE, Meredith D, Halestrap AP: Characterisation of human monocarboxylate transporter 4 substantiates its role in lactic acid efflux from skeletal muscle. J Physiol. 2000 Dec 1;529 Pt 2:285-93. - Pubmed
DTHybrid score 0.7511

Predictions


Id Partner name Gene Name Score
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.2677
3184 3-methyl-2-oxobutanoate hydroxymethyltransferase panB 0.0843
3315 3-methyl-2-oxobutanoate hydroxymethyltransferase panB 0.0843
3179 2-isopropylmalate synthase leuA 0.0843
52 Pyruvate kinase isozymes R/L PKLR 0.0825
3334 Deacetoxycephalosporin C synthetase cefE 0.067
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0658
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.0632
6142 Solute carrier family 22 member 8 SLC22A8 0.0621
2293 Cyclomaltodextrin glucanotransferase Not Available 0.0568
2508 Cyclomaltodextrin glucanotransferase cgt 0.0568
2523 Cyclomaltodextrin glucanotransferase cgt 0.0568
3207 Cyclomaltodextrin glucanotransferase amyA 0.0568
1729 Solute carrier family 22 member 6 SLC22A6 0.0531
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0525
199 Monocarboxylate transporter 8 SLC16A2 0.051
2922 Glycerol kinase glpK 0.0504
3205 Isocitrate lyase icl 0.0466
3078 Regulator of ribonuclease activity A Rv3853 0.0466
1024 Solute carrier family 22 member 11 SLC22A11 0.0449
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0446
4132 Chloride channel protein ClC-Ka CLCNKA 0.044
397 Monocarboxylate transporter 3 SLC16A8 0.0432
195 Monocarboxylate transporter 7 SLC16A6 0.0429
429 Monocarboxylate transporter 6 SLC16A5 0.0428
218 Monocarboxylate transporter 5 SLC16A4 0.0428
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0427
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0425
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0425
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0425
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0425
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0424
1588 Multidrug resistance protein 1 ABCB1 0.042
118 Organic cation/carnitine transporter 2 SLC22A5 0.0415
1566 Corticoliberin CRH 0.0413
587 Serum albumin ALB 0.041
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0404
2597 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] glmS 0.0403
2206 Glucose-6-phosphate isomerase GPI 0.0381
860 Nicotinamide N-methyltransferase NNMT 0.0376
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0376
583 Nicotinate-nucleotide pyrophosphorylase [carboxylating] QPRT 0.0376
2442 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0376
2459 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0376
928 Nicotinic acid receptor 2 GPR109B 0.0376
699 Nicotinic acid receptor 1 GPR109A 0.0376
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0375
6645 D-amino-acid oxidase DAO 0.0373
114 Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 0.0368
2164 Multidrug resistance-associated protein 4 ABCC4 0.0363
862 Multidrug resistance-associated protein 1 ABCC1 0.0361
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.036
4757 Cytochrome P450 2C9 CYP2C9 0.0359
20 Prostaglandin G/H synthase 1 PTGS1 0.0359
771 Pyruvate carboxylase, mitochondrial PC 0.0356
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0352
98 Pyruvate kinase isozymes M1/M2 PKM2 0.0349
6143 Solute carrier family 22 member 7 SLC22A7 0.0348
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0346
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0335
2248 Malate synthase G glcB 0.0335
3190 Malate synthase G glcB 0.0335
6826 Bacilysin biosynthesis protein bacB bacB 0.0328
6827 Probable chorismate mutase pheA 0.0327
6508 Putative uncharacterized protein srtB 0.0327
6543 Putative uncharacterized protein tcp14 0.0327
6615 Putative uncharacterized protein MT0785 0.0327
6623 Putative uncharacterized protein Not Available 0.0327
6806 Putative uncharacterized protein AGR_C_2535 0.0327
6813 Putative uncharacterized protein SAV4671 0.0327
6815 Putative uncharacterized protein AFE_1514 0.0327
6819 Putative uncharacterized protein RUMGNA_03254 0.0327
6825 Putative uncharacterized protein CV_3270 0.0327
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0319
6599 HTH-type transcriptional regulator ttgR ttgR 0.031
6136 Multidrug resistance-associated protein 5 ABCC5 0.0306
2424 L-lactate dehydrogenase ldh 0.03
2641 L-lactate dehydrogenase Not Available 0.03
4437 L-lactate dehydrogenase ldh 0.03
4442 L-lactate dehydrogenase ldh 0.03
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0296
672 Prostaglandin F2-alpha receptor PTGFR 0.0294
4924 Cytochrome P450 2C8 CYP2C8 0.029
2532 Pantoate--beta-alanine ligase panC 0.0285
527 Prostacyclin receptor PTGIR 0.0285
5607 Indole-3-pyruvate decarboxylase ipdC 0.0284
6657 Indole-3-pyruvate decarboxylase ipdC 0.0284
6616 L-phenylalanine dehydrogenase pdh 0.0284
574 Branched-chain-amino-acid aminotransferase, cytosolic BCAT1 0.0271
6500 Phospholipase A2 PLA2G1B 0.027
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0261
3178 Formate acetyltransferase 1 pflB 0.026
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0245
4512 Cytochrome P450 3A4 CYP3A4 0.0245
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0242
6145 Solute carrier family 22 member 1 SLC22A1 0.0237
77 L-lactate dehydrogenase B chain LDHB 0.0232
5925 Neuropeptide Y NPY 0.0231
4119 Cytochrome P450 2D6 CYP2D6 0.023
314 System N amino acid transporter 1 SLC38A3 0.0229
723 Cytosolic phospholipase A2 PLA2G4A 0.0229
6837 Serine/threonine-protein kinase 17B STK17B 0.0225
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.0225
473 L-lactate dehydrogenase A chain LDHA 0.0224
2853 14 kDa fatty acid-binding protein Not Available 0.0219
3676 Phospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitive aroG 0.0216
290 Prostaglandin G/H synthase 2 PTGS2 0.0215
3134 Phospho-2-dehydro-3-deoxyheptonate aldolase aroF 0.0215
6268 Hydroxyacid oxidase 1 HAO1 0.0206
6149 Solute carrier family 22 member 10 SLC22A10 0.0202
4384 Capsule biosynthesis protein synC 0.0199
4069 Threonyl-tRNA synthetase, mitochondrial TARS2 0.0197
261 Threonyl-tRNA synthetase, cytoplasmic TARS 0.0197
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0196
246 Valyl-tRNA synthetase VARS 0.0196
6085 Fatty acid-binding protein, intestinal FABP2 0.0194
1792 Tissue-type plasminogen activator PLAT 0.0193
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0192
6141 Sodium/bile acid cotransporter SLC10A1 0.0188
1116 Phosphoenolpyruvate carboxykinase, cytosolic [GTP] PCK1 0.0188
6144 Solute carrier family 22 member 2 SLC22A2 0.0184
866 Large neutral amino acids transporter small subunit 2 SLC7A8 0.0183
33 Cystine/glutamate transporter SLC7A11 0.0182
763 Tyrosine aminotransferase TAT 0.0177
5493 Tyrosine aminotransferase Not Available 0.0177
6167 Organic solute transporter subunit beta OSTB 0.0174
6166 Organic solute transporter subunit alpha OSTA 0.0174
2599 Tyrosine-protein kinase HCK HCK 0.0171
5469 Head decoration protein shp 0.0168
776 Bile salt export pump ABCB11 0.0166
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0163
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0163
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0163
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0163
2310 2-dehydro-3-deoxyphosphooctonate aldolase kdsA 0.0163
2542 2-dehydro-3-deoxyphosphooctonate aldolase kdsA 0.0163
2457 Bacillolysin nprS 0.016
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0159
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0159
6016 Cytochrome P450 2C19 CYP2C19 0.0158
601 Propionyl-CoA carboxylase beta chain, mitochondrial PCCB 0.0157
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0155
4109 cAMP-specific 3',5'-cyclic phosphodiesterase 4C PDE4C 0.0153
4118 Cytochrome P450 3A5 CYP3A5 0.0153
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0152
534 Threonine synthase-like 1 THNSL1 0.0152
2183 Fatty acid-binding protein, adipocyte FABP4 0.015
676 Tyrosine 3-monooxygenase TH 0.0149
338 DNA polymerase UL30 0.0149
379 DNA polymerase UL54 0.0149
697 DNA polymerase ORF28 0.0149
2482 DNA polymerase 43 0.0149
4104 DNA polymerase BALF5 0.0149
301 Kynurenine--oxoglutarate transaminase 1 CCBL1 0.0148
815 Histidyl-tRNA synthetase, cytoplasmic HARS 0.0147
96 Histidine ammonia-lyase HAL 0.0147
6257 Histidine ammonia-lyase Not Available 0.0147
6536 Histidine ammonia-lyase hutH 0.0147
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.0147
5756 D-alanyl-D-alanine carboxypeptidase dac 0.0147
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0142
38 Cystinosin CTNS 0.0141
3998 B(0,+)-type amino acid transporter 1 SLC7A9 0.0141
1963 Neutral and basic amino acid transport protein rBAT SLC3A1 0.0141
833 Organic cation/carnitine transporter 1 SLC22A4 0.0138
150 Cationic amino acid transporter 3 SLC7A3 0.0137
235 High-affinity cationic amino acid transporter 1 SLC7A1 0.0137
58 Cationic amino acid transporter 4 SLC7A4 0.0137
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.0137
471 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 0.0134
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0133
2358 cAMP-specific 3',5'-cyclic phosphodiesterase 4D PDE4D 0.0131
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.013
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0128
399 Tyrosyl-tRNA synthetase, mitochondrial YARS2 0.0127
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0124
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0121
3977 ASRGL1 protein ASRGL1 0.0121
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0119
263 Neutral amino acid transporter B(0) SLC1A5 0.0119
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0118
3 Histidine decarboxylase HDC 0.0117
349 Serine--pyruvate aminotransferase AGXT 0.0115
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0112
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0111
701 Isoleucine-tRNA synthetase IARS 0.011
546 Isoleucyl-tRNA synthetase, cytoplasmic IARS 0.011
4080 Isoleucyl-tRNA synthetase, mitochondrial IARS2 0.011
3014 Ribonuclease UK114 HRSP12 0.011
5428 Replication protein repA 0.011
3617 Non-heme chloroperoxidase cpo 0.011
5426 Non-heme chloroperoxidase cpo 0.011
5427 Hydroxyquinol 1,2-dioxygenase chqB 0.011
3718 Hydrogen peroxide-inducible genes activator oxyR 0.011
3018 HTH-type transcriptional regulator malT malT 0.011
4200 Cytochrome P450 1A2 CYP1A2 0.011
221 Lysyl-tRNA synthetase KARS 0.0109
4092 Probable asparaginyl-tRNA synthetase, mitochondrial NARS2 0.0107
669 Asparaginyl-tRNA synthetase, cytoplasmic NARS 0.0107
358 Cystathionine beta-synthase CBS 0.0106
6218 Pannexin-1 PANX1 0.0101
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.01
72 Seryl-tRNA synthetase, cytoplasmic SARS 0.0099
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0099
501 Leucine carboxyl methyltransferase 1 LCMT1 0.0097
675 Leucine carboxyl methyltransferase 2 LCMT2 0.0097
846 Leucyl-tRNA synthetase, cytoplasmic LARS 0.0097
227 Probable leucyl-tRNA synthetase, mitochondrial LARS2 0.0097
42 Phenylalanyl-tRNA synthetase alpha chain FARSA 0.0096
6602 Phenylalanyl-tRNA synthetase alpha chain pheS 0.0096
31 Phenylalanyl-tRNA synthetase, mitochondrial FARS2 0.0096
618 Phenylalanyl-tRNA synthetase beta chain FARSB 0.0096
6603 Phenylalanyl-tRNA synthetase beta chain pheT 0.0096
619 Low-affinity cationic amino acid transporter 2 SLC7A2 0.0095
2958 Probable tautomerase ydcE pptA 0.0095
2573 Cocaine esterase cocE 0.0094
7263 Cocaine esterase Not Available 0.0094
482 Glycine receptor subunit alpha-1 GLRA1 0.0093
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0093
3115 Ras-related protein Rab-9 RAB9A 0.0093
3603 Chlorocatechol 1,2-dioxygenase clcA 0.0093
828 Phenylalanine-4-hydroxylase PAH 0.0092
3109 Phenylalanine-4-hydroxylase phhA 0.0092
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0092
256 Tyrosyl-tRNA synthetase, cytoplasmic YARS 0.0089
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0089
5122 Mersacidin decarboxylase mrsD 0.0088
5078 Amine oxidase, flavin-containing PSPTO1126 0.0088
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0088
5115 FkbI fkbI 0.0088
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0088
5095 Putidaredoxin reductase camA 0.0088
3763 5,10-methylenetetrahydrofolate reductase metF 0.0088
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0088
5094 5,10-methylenetetrahydrofolate reductase metF 0.0088
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0088
526 Thioredoxin reductase trxB 0.0088
3767 Thioredoxin reductase trxB 0.0088
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0088
3133 UDP-galactopyranose mutase glf 0.0088
5099 UDP-galactopyranose mutase glf 0.0088
5109 Outer membrane protein p64k or PM-6 m-6 0.0088
5081 L-aspartate oxidase nadB 0.0088
5111 Phenylacetone monooxygenase pamO 0.0088
5083 Cryptochrome DASH cry 0.0088
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0088
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0088
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0088
1410 Oxidoreductase HSD17B6 0.0088
4725 Oxidoreductase Not Available 0.0088
5124 Oxidoreductase Not Available 0.0088
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0088
6030 Cytochrome P450 2B6 CYP2B6 0.0085
558 Solute carrier family 12 member 1 SLC12A1 0.0084
357 Carbonic anhydrase 2 CA2 0.0084
318 Alpha-2A adrenergic receptor ADRA2A 0.0084
5718 Cytochrome P450 2A6 CYP2A6 0.0082
169 Cysteine desulfurase, mitochondrial NFS1 0.0081
1119 Peroxiredoxin-5, mitochondrial PRDX5 0.0079
556 Alpha-1A adrenergic receptor ADRA1A 0.0078
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0078
4486 Phenol 2-hydroxylase component B pheA2 0.0077
4439 Ferredoxin reductase bphA4 0.0077
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0077
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0077
5073 Ferredoxin--NADP reductase petH 0.0077
5076 Ferredoxin--NADP reductase fpr 0.0077
5119 Ferredoxin--NADP reductase petH 0.0077
5121 Ferredoxin--NADP reductase fpr 0.0077
3594 Deoxyribodipyrimidine photo-lyase phr 0.0077
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0077
5080 Deoxyribodipyrimidine photo-lyase phr 0.0077
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0077
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0077
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0077
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0077
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0077
2470 Pyruvate oxidase pox5 0.0077
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0077
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0077
2526 NADPH-ferredoxin reductase fprA fprA 0.0077
4477 Dihydrolipoyl dehydrogenase lpdV 0.0077
5077 Dihydrolipoyl dehydrogenase Not Available 0.0077
5117 Dihydrolipoyl dehydrogenase lpd 0.0077
2268 Cholesterol oxidase choB 0.0077
2822 Cholesterol oxidase choA 0.0077
5072 N,N-dimethylglycine oxidase dmg 0.0077
184 L-serine dehydratase SDS 0.0076
431 Serine racemase SRR 0.0076
491 Serine palmitoyltransferase 1 SPTLC1 0.0076
727 Serine palmitoyltransferase 2 SPTLC2 0.0076
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0076
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0074
6106 Cytochrome P450 2C18 CYP2C18 0.0074
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0073
4674 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase cumD 0.0073
90 Tryptophan 5-hydroxylase 2 TPH2 0.0073
4063 Tryptophanyl-tRNA synthetase, mitochondrial WARS2 0.0073
2693 Heat-labile enterotoxin B chain eltB 0.0072
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0072
2893 Glycine oxidase thiO 0.0071
3102 Flavohemoprotein hmp 0.0071
4969 Flavohemoprotein hmp 0.0071
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0071
4440 NADH peroxidase npr 0.0071
468 Cytochrome P450 4A11 CYP4A11 0.0071
76 Nitric-oxide synthase, brain NOS1 0.0068
6107 Cytochrome P450 3A7 CYP3A7 0.0068
2567 Thymidylate synthase thyX thyX 0.0067
2823 Trypanothione reductase TPR 0.0067
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0067
543 Penicillin-binding protein 1B mrcB 0.0067
6186 Penicillin-binding protein 1B ponB 0.0067
6822 Penicillin-binding protein 1b pbp1b 0.0067
6844 Penicillin-binding protein 1b pbp1b 0.0067
740 Argininosuccinate synthase ASS1 0.0067
865 Argininosuccinate synthase ASS1 0.0067
2680 Argininosuccinate synthase argG 0.0067
3194 Argininosuccinate synthase argG 0.0067
594 Thyroxine-binding globulin SERPINA7 0.0066
668 Glutamate--cysteine ligase regulatory subunit GCLM 0.0066
2452 Tryptophanyl-tRNA synthetase trpS 0.0066
645 Penicillin-binding protein 1A mrcA 0.0065
5805 Penicillin-binding protein 1A ponA 0.0065
6185 Penicillin-binding protein 1A mrcA 0.0065
6799 Penicillin-binding protein 1A pbpA 0.0065
320 5-hydroxytryptamine 1A receptor HTR1A 0.0064
6148 Multidrug resistance-associated protein 7 ABCC10 0.0064
159 Penicillin-binding protein 2B penA 0.0064
6121 Penicillin-binding protein 2B penA 0.0064
2769 P-hydroxybenzoate hydroxylase pobA 0.0064
2809 P-hydroxybenzoate hydroxylase pobA 0.0064
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0063
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0063
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0063
2380 Monomeric sarcosine oxidase soxA 0.0062
6024 Cytochrome P450 1A1 CYP1A1 0.0061
327 Glutathione reductase gor 0.0061
5110 Glutathione reductase GR2 0.0061
3426 Glutamine synthetase glnA 0.0061
3987 Glutamine synthetase GLUL 0.0061
126 D-lactate dehydrogenase dld 0.0061
3545 D-lactate dehydrogenase Not Available 0.0061
4510 D-lactate dehydrogenase ldhA 0.0061
758 Thyroid hormone receptor alpha THRA 0.0061
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0061
605 Fumarate reductase flavoprotein subunit frdA 0.006
2709 Fumarate reductase flavoprotein subunit SO_0970 0.006
3673 Fumarate reductase flavoprotein subunit fccA 0.006
4912 Fumarate reductase flavoprotein subunit ifcA 0.006
6549 Fumarate reductase flavoprotein subunit frdA 0.006
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.006
252 Tryptophanyl-tRNA synthetase, cytoplasmic WARS 0.0059
765 Indoleamine 2,3-dioxygenase IDO1 0.0059
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0059
6137 Multidrug resistance-associated protein 6 ABCC6 0.0059
3587 Gastrotropin FABP6 0.0058
532 Neutral amino acid transporter A SLC1A4 0.0057
4070 Probable alanyl-tRNA synthetase, mitochondrial AARS2 0.0057
323 Alanyl-tRNA synthetase, cytoplasmic AARS 0.0057
186 Glutamate--cysteine ligase catalytic subunit GCLC 0.0057
1898 Cytochrome P450 1B1 CYP1B1 0.0055
735 Alanine aminotransferase 1 GPT 0.0055
3904 Alanine aminotransferase 2 GPT2 0.0055
134 Tryptophan 5-hydroxylase 1 TPH1 0.0055
346 Thyroid hormone receptor beta-1 THRB 0.0054
6012 Tryptophan 2,3-dioxygenase TDO2 0.0053
275 Arachidonate 5-lipoxygenase ALOX5 0.0053
171 Cysteine dioxygenase CDO-1 0.0053
774 Cysteinyl-tRNA synthetase, cytoplasmic CARS 0.0052
1314 Thiamine transporter 2 SLC19A3 0.0052
4064 Probable cysteinyl-tRNA synthetase, mitochondrial CARS2 0.0052
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0052
207 Glutathione synthetase GSS 0.0052
5269 Glutathione synthetase gshB 0.0052
4533 Glyoxalase family protein BC_1747 0.0051
834 Arginase-2, mitochondrial ARG2 0.0051
593 Proton-coupled amino acid transporter 1 SLC36A1 0.0051
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0051
577 Argininosuccinate lyase ASL 0.0049
499 Arginine decarboxylase ADC 0.0049
3971 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase CAD 0.0049
941 Betaine--homocysteine S-methyltransferase 1 BHMT 0.0048
480 Methionine-R-sulfoxide reductase B2 MSRB2 0.0048
317 Methionine-R-sulfoxide reductase SEPX1 0.0048
3996 Betaine--homocysteine S-methyltransferase 2 BHMT2 0.0048
3921 Methionine adenosyltransferase 2 subunit beta MAT2B 0.0048
3995 Methionyl-tRNA synthetase, mitochondrial MARS2 0.0048
600 Methionyl-tRNA synthetase, cytoplasmic MARS 0.0048
4037 Hypothetical protein GPX1 0.0047
4297 Hypothetical protein SP_1951 0.0047
4521 Hypothetical protein BC_2969 0.0047
4540 Hypothetical protein TM_1070 0.0047
4555 Hypothetical protein MT1739 0.0047
4569 Hypothetical protein mshD 0.0047
4578 Hypothetical protein PA3270 0.0047
4747 Hypothetical protein PA3967 0.0047
5177 Hypothetical protein TM_0096 0.0047
5194 Hypothetical protein PA1204 0.0047
5240 Hypothetical protein Rv2991 0.0047
5370 Hypothetical protein TM_1158 0.0047
5710 Hypothetical protein Tb927.5.1360 0.0047
4545 Molybdopterin-converting factor subunit 2 moaE 0.0047
4527 Putative hydrolase ycdX ycdX 0.0047
4106 Guanylate kinase GUK1 0.0047
4516 Guanylate kinase gmk 0.0047
4538 Hypothetical protein VC1899 VC_1899 0.0047
4536 Transcriptional regulator, IclR family TM_0065 0.0047
2501 Protein ygbM ygbM 0.0047
4514 Citrate lyase beta subunit-like protein citE 0.0047
4781 Citrate lyase beta subunit-like protein DR_1240 0.0047
4524 Mannose-6-phosphate isomerase yvyI 0.0047
4522 Arginine N-succinyltransferase subunit alpha astA 0.0047
4547 Iron binding protein FbpA fbpA 0.0047
4529 Oxalate decarboxylase oxdC oxdC 0.0047
4546 Aminotransferase, putative TM_1131 0.0047
658 Para-aminobenzoate synthase component 1 pabB 0.0047
4526 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein TM_1223 0.0047
4535 Glutaconyl-CoA decarboxylase subunit alpha gcdA 0.0047
4548 Gyrase B gyrB 0.0047
4515 Peripheral plasma membrane protein CASK CASK 0.0047
3583 6-phosphogluconolactonase pgl 0.0047
714 Glutathione reductase, mitochondrial GSR 0.0047
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0047
3991 Glutamine-dependent NAD(+) synthetase NADSYN1 0.0046
3984 Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial PET112L 0.0046
5 Glutaminase liver isoform, mitochondrial GLS2 0.0046
917 Glutaminase kidney isoform, mitochondrial GLS 0.0046
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0046
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0046
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0046
5261 Phosphoribosylformylglycinamidine synthase purL 0.0046
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0045
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0045
5682 Ribonuclease pancreatic RNASE1 0.0045
136 Estrogen receptor ESR1 0.0045
3917 Methylenetetrahydrofolate reductase MTHFR 0.0045
3899 Alanine--glyoxylate aminotransferase 2-like 2 AGXT2L2 0.0044
6013 Cytochrome P450 2E1 CYP2E1 0.0044
1671 Excitatory amino acid transporter 3 SLC1A1 0.0043
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0043
1999 Methylated-DNA--protein-cysteine methyltransferase MGMT 0.0043
4496 C-terminal-binding protein 1 CTBP1 0.0043
3811 Cytochrome P450 19A1 CYP19A1 0.0042
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0042
210 Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase EPRS 0.0042
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0042
3877 Growth-inhibiting protein 18 GIG18 0.0042
435 Kynureninase KYNU 0.0041
4654 Kynureninase kynU 0.0041
492 Histamine H1 receptor HRH1 0.0041
4532 Gephyrin GPHN 0.0041
56 Delta-aminolevulinic acid dehydratase ALAD 0.0041
2356 Delta-aminolevulinic acid dehydratase hemB 0.0041
3613 Delta-aminolevulinic acid dehydratase hemB 0.0041
3674 Delta-aminolevulinic acid dehydratase hemB 0.0041
3237 Beta-lactamase OXA-2 bla 0.0041
4542 Glutaminase 1 glsA1 0.0041
4544 Glutaminase 1 glsA1 0.0041
191 Peptide methionine sulfoxide reductase MSRA 0.0041
2929 (S)-2-haloacid dehalogenase dhlB 0.0041
2995 (S)-2-haloacid dehalogenase Not Available 0.0041
4528 Phenazine biosynthesis protein PhzD phzD1 0.0041
3759 Glutathione S-transferase gst 0.004
4541 Glutathione S-transferase GST 0.004
89 Cysteine sulfinic acid decarboxylase CSAD 0.004
373 Transthyretin TTR 0.004
3261 Signal recognition particle protein ffh 0.004
4517 Probable butyrate kinase 2 buk2 0.004
426 Aspartate aminotransferase, mitochondrial GOT2 0.004
626 Cysteine dioxygenase type 1 CDO1 0.004
4120 NADPH--cytochrome P450 reductase POR 0.0039
2230 Catalase CAT 0.0039
3249 Catalase katA 0.0039
3625 Catalase katA 0.0039
4539 Catalase katA 0.0039
4941 Catalase katB 0.0039
334 S-adenosylmethionine synthetase isoform type-2 MAT2A 0.0038
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0037
3467 Methylglyoxal synthase mgsA 0.0037
2775 Dihydroorotate dehydrogenase pyrD 0.0037
4531 Putative ketoacyl reductase actIII 0.0037
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0036
921 Glutamate receptor 2 GRIA2 0.0036
1039 Histone deacetylase 9 HDAC9 0.0036
868 Cystathionine gamma-lyase CTH 0.0035
2525 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0035
3201 3-phosphoshikimate 1-carboxyvinyltransferase aroA 0.0035
4085 Peptidyl-prolyl cis-trans isomerase C PPIC 0.0035
4088 Probable prolyl-tRNA synthetase, mitochondrial PARS2 0.0035
4083 Peptidyl-prolyl cis-trans isomerase H PPIH 0.0035
4087 Pyrroline 5-carboxylate reductase isoform P5CR2 0.0035
4090 Chromosome 14 open reading frame 149 C14orf149 0.0035
4082 Proline oxidase, mitochondrial PRODH 0.0035
797 Sodium-dependent proline transporter SLC6A7 0.0035
4086 Peptidyl-prolyl cis-trans isomerase G PPIG 0.0035
3939 Amine oxidase [flavin-containing] B MAOB 0.0034
1517 Beta-3 adrenergic receptor ADRB3 0.0034
2688 Peptide deformylase def 0.0033
2708 Peptide deformylase def 0.0033
3004 Peptide deformylase def 0.0033
4337 Peptide deformylase def 0.0033
4338 Peptide deformylase def 0.0033
5368 Peptide deformylase def 0.0033
5371 Peptide deformylase def 0.0033
6375 Peptide deformylase def 0.0033
6378 Peptide deformylase def 0.0033
6379 Peptide deformylase def 0.0033
6776 Peptide deformylase def 0.0033
6900 Peptide deformylase def 0.0033
4534 Cytohesin-2 CYTH2 0.0033
3947 Xanthine dehydrogenase/oxidase XDH 0.0033
840 Methionine synthase reductase, mitochondrial MTRR 0.0033
2548 Subtilisin Carlsberg apr 0.0032
163 D(1B) dopamine receptor DRD5 0.0032
4269 Hypoxanthine-guanine phosphoribosyltransferase, putative HGPRTase 0.0032
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0032
2632 Adenylosuccinate synthetase purA 0.0031
3323 Adenylosuccinate synthetase purA 0.0031
3975 Adenylosuccinate synthetase ADSS 0.0031
4598 Adenylosuccinate synthetase Adss 0.0031
6817 Adenylosuccinate synthetase purA 0.0031
3972 Adenylosuccinate synthetase isozyme 2 ADSS 0.0031
533 Aminoacylase-1 ACY1 0.0031
3969 Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole- succinocarboxamide synthase PAICS 0.0031
799 Aspartyl-tRNA synthetase, cytoplasmic DARS 0.0031
209 Aspartoacylase ASPA 0.0031
3979 Aspartoacylase-2 ACY3 0.0031
3976 Aspartyl-tRNA synthetase, mitochondrial DARS2 0.0031
513 Calcium-binding mitochondrial carrier protein Aralar2 SLC25A13 0.0031
305 Mitochondrial aspartate-glutamate carrier protein SLC25A13 0.0031
262 Calcium-binding mitochondrial carrier protein Aralar1 SLC25A12 0.0031
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0031
2021 Thrombomodulin THBD 0.0031
809 Methionine synthase MTR 0.0031
2935 Methionine synthase metH 0.0031
432 D(4) dopamine receptor DRD4 0.003
3941 Amine oxidase [flavin-containing] A MAOA 0.003
5818 Folate receptor alpha FOLR1 0.003
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.003
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.003
4084 Peptidyl-prolyl cis-trans isomerase B PPIB 0.003
638 D(3) dopamine receptor DRD3 0.0029
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0029
4000 Prolyl 4-hydroxylase subunit alpha-2 P4HA2 0.0029
7 Nitric oxide synthase, inducible NOS2 0.0029
1008 CTP synthase 1 CTPS 0.0029
3988 Protein-glutamine gamma-glutamyltransferase K TGM1 0.0029
3985 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 GFPT2 0.0029
3990 Protein-glutamine gamma-glutamyltransferase 4 TGM4 0.0029
3986 Protein-glutamine gamma-glutamyltransferase 6 TGM6 0.0029
3992 Protein-glutamine gamma-glutamyltransferase Z TGM7 0.0029
3983 Protein-glutamine gamma-glutamyltransferase 5 TGM5 0.0029
3989 Glutaminyl-tRNA synthetase QARS 0.0029
291 Nitric-oxide synthase, endothelial NOS3 0.0029
760 Fibroblast growth factor 1 FGF1 0.0027
810 Heme oxygenase 1 HMOX1 0.0027
3391 Heme oxygenase 1 pbsA1 0.0027
3874 Proline synthetase co-transcribed bacterial homolog protein PROSC 0.0027
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0027
3027 Streptavidin Not Available 0.0027
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0027
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0027
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0027
585 Aspartyl/asparaginyl beta-hydroxylase ASPH 0.0027
2554 Peptidyl-prolyl cis-trans isomerase, mitochondrial PPIF 0.0027
293 Gamma-glutamyl hydrolase GGH 0.0026
2795 Methionine aminopeptidase 2 METAP2 0.0026
23 D(1A) dopamine receptor DRD1 0.0026
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0026
789 Alpha-1D adrenergic receptor ADRA1D 0.0026
3949 Prolyl 3-hydroxylase 2 LEPREL1 0.0025
3945 Prolyl 3-hydroxylase 1 LEPRE1 0.0025
3951 Prolyl 3-hydroxylase 3 LEPREL2 0.0025
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0025
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0025
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0025
378 Alpha-2C adrenergic receptor ADRA2C 0.0025
831 D(2) dopamine receptor DRD2 0.0024
411 Glycine N-methyltransferase GNMT 0.0024
1596 Protein-glutamine gamma-glutamyltransferase 2 TGM2 0.0024
629 Alpha-2B adrenergic receptor ADRA2B 0.0024
1650 Heme carrier protein 1 SLC46A1 0.0024
4024 Mitochondrial glutamate carrier 2 SLC25A18 0.0024
4025 Mitochondrial glutamate carrier 1 SLC25A22 0.0024
4021 Probable glutamyl-tRNA synthetase, mitochondrial EARS2 0.0024
4023 N-acetylglutamate synthase, mitochondrial NAGS 0.0024
1912 Excitatory amino acid transporter 1 SLC1A3 0.0024
4019 Excitatory amino acid transporter 4 SLC1A6 0.0024
4026 Aspartyl aminopeptidase DNPEP 0.0024
664 Glutamate decarboxylase 2 GAD2 0.0024
3890 Glutamate decarboxylase 2 GAD2 0.0024
4022 Glutamate--ammonia ligase domain-containing protein 1 LGSN 0.0024
922 Glutamate receptor 4 GRIA4 0.0024
4016 Excitatory amino acid transporter 5 SLC1A7 0.0024
1047 Excitatory amino acid transporter 2 SLC1A2 0.0024
4018 Glutamate receptor delta-2 subunit GRID2 0.0024
927 Metabotropic glutamate receptor 8 GRM8 0.0024
4020 Glutamyl aminopeptidase ENPEP 0.0024
926 Metabotropic glutamate receptor 7 GRM7 0.0024
915 Delta 1-pyrroline-5-carboxylate synthetase ALDH18A1 0.0024
920 Glutamate receptor, ionotropic kainate 5 GRIK5 0.0024
4017 5-oxoprolinase OPLAH 0.0024
925 Metabotropic glutamate receptor 4 GRM4 0.0024
924 Glutamate receptor, ionotropic kainate 3 GRIK3 0.0024
919 Glutamate receptor, ionotropic kainate 4 GRIK4 0.0024
4027 Glutamate receptor delta-1 subunit GRID1 0.0024
193 Beta-1 adrenergic receptor ADRB1 0.0024
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0024
6 Coagulation factor XIII A chain F13A1 0.0024
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0024
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0023
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0023
766 Beta-2 adrenergic receptor ADRB2 0.0023
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0023
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0023
632 Alpha-1B adrenergic receptor ADRA1B 0.0023
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0023
413 Amidophosphoribosyltransferase PPAT 0.0023
2515 Amidophosphoribosyltransferase purF 0.0023
3714 Amidophosphoribosyltransferase purF 0.0023
6220 Aryl hydrocarbon receptor AHR 0.0023
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0022
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0022
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0022
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0022
4058 Glycine N-acyltransferase-like protein 2 GLYATL2 0.0022
4057 Glycine N-acyltransferase GLYAT 0.0022
4059 Glycine N-acyltransferase-like protein 1 GLYATL1 0.0022
4056 N-arachidonyl glycine receptor GPR18 0.0022
4061 Peroxisomal sarcosine oxidase PIPOX 0.0022
4055 Bile acid CoA:amino acid N-acyltransferase BAAT 0.0022
1236 Sodium- and chloride-dependent glycine transporter 1 SLC6A9 0.0022
4062 Sodium- and chloride-dependent glycine transporter 2 SLC6A5 0.0022
4060 Vesicular inhibitory amino acid transporter SLC32A1 0.0022
1088 5-aminolevulinate synthase, erythroid-specific, mitochondrial ALAS2 0.0022
1466 Glycyl-tRNA synthetase GARS 0.0022
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0021
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0021
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0021
625 Glutamate carboxypeptidase 2 FOLH1 0.0021
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0021
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0021
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0021
273 Apoptosis regulator Bcl-2 BCL2 0.0021
3978 Adenylosuccinate synthetase isozyme 1 ADSSL1 0.0021
2339 Protein-glutamine gamma-glutamyltransferase E TGM3 0.002
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.002
284 DNA-directed RNA polymerase beta chain rpoB 0.002
5773 DNA-directed RNA polymerase beta chain rpoB 0.002
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.002
665 Phosphoserine aminotransferase PSAT1 0.0019
4652 Phosphoserine aminotransferase serC 0.0019
801 Kynurenine/alpha-aminoadipate aminotransferase mitochondrial AADAT 0.0019
3895 Kynurenine--oxoglutarate transaminase 3 CCBL2 0.0019
420 Glutamate decarboxylase 1 GAD1 0.0019
3900 Glutamate decarboxylase 1 GAD1 0.0019
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0019
916 Metabotropic glutamate receptor 1 GRM1 0.0019
923 Glutamate receptor 3 GRIA3 0.0019
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0018
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0018
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0018
24 Thymidylate synthase TMP1 0.0018
359 Thymidylate synthase TYMS 0.0018
2626 Thymidylate synthase thyA 0.0018
2729 Thymidylate synthase thyA 0.0018
5352 Thymidylate synthase THYA 0.0018
365 Dihydrofolate reductase DHFR 0.0018
2381 Dihydrofolate reductase DFR1 0.0018
2833 Dihydrofolate reductase Not Available 0.0018
2931 Dihydrofolate reductase folA 0.0018
3544 Dihydrofolate reductase folA 0.0018
3682 Dihydrofolate reductase folA 0.0018
6642 Dihydrofolate reductase folA 0.0018
6756 Dihydrofolate reductase dfrA 0.0018
6020 Aldehyde oxidase AOX1 0.0018
4054 Glycine cleavage system H protein, mitochondrial GCSH 0.0017
914 Formimidoyltransferase-cyclodeaminase FTCD 0.0017
455 5-aminolevulinate synthase, nonspecific, mitochondrial ALAS1 0.0017
575 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial GCAT 0.0017
681 Glycine dehydrogenase [decarboxylating], mitochondrial GLDC 0.0017
62 Glycine receptor subunit beta GLRB 0.0017
3810 Catechol O-methyltransferase COMT 0.0017
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0016
383 Glycine amidinotransferase, mitochondrial GATM 0.0016
952 Dipeptidyl peptidase 4 DPP4 0.0016
6031 Cytochrome P450 3A43 CYP3A43 0.0016
3884 SHMT2 protein SHMT2 0.0015
3901 SHMT2 protein SHMT2 0.0015
3885 Hypothetical protein DKFZp686P09201 DKFZp686P09201 0.0015
3879 Serine hydroxymethyltransferase 2 Not Available 0.0015
321 Serine hydroxymethyltransferase, mitochondrial SHMT2 0.0015
705 Glutamate receptor 1 GRIA1 0.0015
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0015
756 Sex hormone-binding globulin SHBG 0.0014
820 Glycine receptor subunit alpha-2 GLRA2 0.0014
461 Glycine receptor subunit alpha-3 GLRA3 0.0014
367 Serine hydroxymethyltransferase, cytosolic SHMT1 0.0014
869 Estrogen receptor beta ESR2 0.0013
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0013
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0013
4992 Cytochrome c peroxidase Not Available 0.0013
5590 N utilization substance protein B homolog nusB 0.0012
5598 Glycerol uptake operon antiterminator-related protein TM_1436 0.0012
5586 Pleckstrin homology domain-containing family A member 1 PLEKHA1 0.0012
5577 N5-carboxyaminoimidazole ribonucleotide mutase purE 0.0012
2300 Lysozyme E 0.0012
3633 Lysozyme R 0.0012
5597 Lysozyme 17 0.0012
3792 KHG/KDPG aldolase [Includes: 4-hydroxy-2-oxoglutarate aldolase eda 0.0012
2838 Ribose-5-phosphate isomerase A rpiA 0.0012
2952 Ribose-5-phosphate isomerase A rpiA 0.0012
5595 Ribose-5-phosphate isomerase A rpiA 0.0012
4695 UPF0124 protein yfiH yfiH 0.0012
5060 Intron-associated endonuclease 1 ITEVIR 0.0012
5593 Transferase Not Available 0.0012
5588 Cell division protein FtsY TM_0570 0.0012
5591 Complement component C8 gamma chain C8G 0.0012
5587 Iron(III)-binding periplasmic protein fbpA 0.0012
5583 RNA 3'-terminal phosphate cyclase rtcA 0.0012
5582 Regulator of transcription; stringent starvation protein A sspA 0.0012
4238 50S ribosomal protein L4 rplD 0.0012
5578 50S ribosomal protein L4 rplD 0.0012
6173 50S ribosomal protein L4 rplD 0.0012
6219 50S ribosomal protein L4 rplD 0.0012
5592 Ribonucleoside-diphosphate reductase subunit beta nrdF 0.0012
5581 Beta-fructosidase bfrA 0.0012
5600 Pyruvate decarboxylase pdc 0.0012
4375 Glutamine synthetase 1 glnA1 0.0012
5575 Short tail fiber protein 12 0.0012
5580 Hexon protein PII 0.0012
5574 Invasin YPTB1668 0.0012
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0012
6147 Solute carrier family 22 member 3 SLC22A3 0.0012
1467 Tumor necrosis factor ligand superfamily member 13B TNFSF13B 0.0011
3132 Tryptophan synthase alpha chain trpA 0.0011
6568 Tryptophan synthase alpha chain trpA 0.0011
5006 RNASE4 protein RNASE4 0.0011
2555 Pol polyprotein pol 0.0011
3242 Pol polyprotein gag-pol 0.0011
3471 Pol polyprotein gag-pro-pol 0.0011
5256 Pol polyprotein pol 0.0011
6469 Pol polyprotein gag-pol 0.0011
6565 Pol polyprotein Not Available 0.0011
3085 Molybdopterin-guanine dinucleotide biosynthesis protein A mobA 0.0011
5328 Prostaglandin F synthase Tb11.02.2310 0.0011
3729 Citrate synthase gltA 0.0011
4575 Citrate synthase cit 0.0011
4580 Citrate synthase gltA 0.0011
5599 3-carboxy-cis,cis-muconate cycloisomerase pcaB 0.0011
4366 Riboflavin kinase/FMN adenylyltransferase TM_0857 0.001
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.001
2603 Beta-lactamase II blm 0.001
2521 Cell division protein ftsZ ftsZ 0.001
3301 Cell division protein ftsZ ftsZ 0.001
2149 Angiogenin ANG 0.001
857 Malate dehydrogenase, mitochondrial MDH2 0.001
2942 Sialidase nanH 0.0009
3546 Sialidase nedA 0.0009
3486 Fumarate hydratase class II fumC 0.0009
1123 Eosinophil cationic protein RNASE3 0.0009
332 Beta-lactamase blaZ 0.0009
2478 Beta-lactamase ampC 0.0009
2613 Beta-lactamase ampC 0.0009
2635 Beta-lactamase ampC 0.0009
2700 Beta-lactamase penP 0.0009
5445 Beta-lactamase blaB 0.0009
6019 Beta-lactamase SHV-7 0.0009
6701 Beta-lactamase cphA 0.0009
2869 1-deoxy-D-xylulose 5-phosphate reductoisomerase dxr 0.0009
2286 Isocitrate dehydrogenase [NADP] icd 0.0009
2302 Isocitrate dehydrogenase [NADP] icd 0.0009
2771 Isocitrate dehydrogenase [NADP] icd 0.0009
2697 Uridine-cytidine kinase 2 UCK2 0.0009
2805 Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 HS3ST3A1 0.0009
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0009
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0009
5579 Carboxypeptidase B CPB1 0.0008
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0008
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0008
3384 Macrophage migration inhibitory factor MIF 0.0008
128 Adenine phosphoribosyltransferase APRT 0.0008
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0007
822 Aldose reductase AKR1B1 0.0006
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