DT-Web

NADP-dependent glyceraldehyde-3-phosphate dehydrogenase


Partner ID 4628
Name NADP-dependent glyceraldehyde-3-phosphate dehydrogenase
Synonyms 6989
Gene name gapN
General function Involved in oxidoreductase activity
Specific function D-glyceraldehyde 3-phosphate + NADP(+) + H(2)O = 3-phospho-D-glycerate + NADPH
Gene sequence + ...

TTGACAAAACAATATAAAAATTATGTCAATGGCGAGTGGAAGCTTTCAGAAAATGAAATTAAAATCTACGAACCAGCCAGTGGAGCTGAATTGGGTTCAGTTCCAGCAATGAGTACTGAAGAAGTAGATTATGTTTATGCTTCAGCCAAGAAAGCTCAACCAGCTTGGCGAGCACTTTCATACATAGAACGTGCTGCCTACCTTCATAAGGTAGCAGATATTTTGATGCGTGATAAAGAAAAAATAGGTGCTATTCTTTCCAAAGAGGTTGCTAAAGGTTATAAATCAGCAGTCAGCGAAGTTGTTCGTACTGCAGAAATCATTAATTATGCAGCTGAAGAAGGTCTTCGTATGGAAGGTGAAGTCCTTGAAGGCGGCAGTTTTGAAGCAGCCAGCAAGAAAAAAATTGCCGTTGTTCGTCGTGAACCAGTAGGTCTTGTATTAGCTATTTCACCATTTAACTACCCTGTTAACTTGGCAGGTTCGAAAATTGCACCGGCTCTTATTGCGGGAAATGTTATTGCTTTTAAACCACCGACGCAAGGATCAATCTCAGGGCTCTTACTTGCTGAAGCATTTGCTGAAGCTGGACTTCCTGCAGGTGTCTTTAATACCATTACAGGTCGTGGTTCTGAAATTGGAGACTATATTGTAGAACATCAAGCCGTTAACTTTATCAATTTCACTGGTTCAACAGGAATTGGCGAACGTATTGGCAAAATGGCTGGTATGCGTCCGATTATGCTTGAACTCGGTGGAAAAGATTCAGCCATCGTTCTTGAAGATGCGGACCTTGAATTGACTGCTAAAAATATTATTGCAGGTGCTTTTGGTTATTCAGGTCAACGCTGTACAGCAGTTAAACGTGTTCTTGTGATGGAAAGTGTTGCTGATGAACTGGTCGAAAAAATCCGTGAAAAAGTTCTTGCATTAACAATTGGTAATCCAGAAGACGATGCAGATATTACACCGTTGATTGATACAAAATCAGCTGATTATGTAGAAGGTCTTATTAATGATGCCAATGATAAAGGAGCCACTGCCCTTACTGAAATCAAACGTGAAGGTAATCTTATCTGTCCAATCCTCTTTGATAAGGTAACGACAGATATGCGTCTTGCTTGGGAAGAACCATTTGGTCCTGTTCTTCCGATCATTCGTGTGACATCTGTAGAAGAAGCCATTGAAATTTCTAACAAATCGGAATATGGACTTCAGGCTTCTATCTTTACAAATGATTTCCCACGCGCTTTTGGTATTGCTGAGCAGCTTGAAGTTGGTACAGTTCATATCAATAATAAGACACAGCGCGGCACGGACAACTTCCCATTCTTAGGGGCTAAAAAATCAGGTGCAGGTATTCAAGGGGTAAAATATTCTATTGAAGCTATGACAACTGTTAAATCCGTCGTATTTGATATCAAATAA
Protein sequence + ...

MTKQYKNYVNGEWKLSENEIKIYEPASGAELGSVPAMSTEEVDYVYASAKKAQPAWRSLSYIERAAYLHKVADILMRDKEKIGAVLSKEVAKGYKSAVSEVVRTAEIINYAAEEGLRMEGEVLEGGSFEAASKKKIAVVRREPVGLVLAISPFNYPVNLAGSKIAPALIAGNVIAFKPPTQGSISGLLLAEAFAEAGLPAGVFNTITGRGSEIGDYIVEHQAVNFINFTGSTGIGERIGKMAGMRPIMLELGGKDSAIVLEDADLELTAKNIIAGAFGYSGQRCTAVKRVLVMESVADELVEKIREKVLALTIGNPEDDADITPLIDTKSADYVEGLINDANDKGAAALTEIKREGNLICPILFDKVTTDMRLAWEEPFGPVLPIIRVTSVEEAIEISNKSEYGLQASIFTNDFPRAFGIAEQLEVGTVHINNKTQRGTDNFPFLGAKKSGAGIQGVKYSIEAMTTVKSVVFDIK
GO Classification
function
catalytic activity
oxidoreductase activity
process
physiological process
metabolism
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB02263 Glyceraldehyde-3-Phosphate
DB03461 2'-Monophosphoadenosine 5'-Diphosphoribose

Associated as Prediction

Id Name
DB00116 Tetrahydrofolic acid
DB00119 Pyruvic acid
DB00140 Riboflavin
DB00155 L-Citrulline
DB00157 NADH
DB00166 Lipoic Acid
DB00175 Pravastatin
DB00205 Pyrimethamine
DB00227 Lovastatin
DB00266 Dicumarol
DB00305 Mitomycin
DB00439 Cerivastatin
DB00440 Trimethoprim
DB00563 Methotrexate
DB00605 Sulindac
DB00635 Prednisone
DB00641 Simvastatin
DB00642 Pemetrexed
DB00665 Nilutamide
DB00694 Daunorubicin
DB00695 Furosemide
DB00698 Nitrofurantoin
DB00770 Alprostadil
DB00865 Benzphetamine
DB00898 Ethanol
DB00905 Bimatoprost
DB00917 Dinoprostone
DB00936 Salicyclic acid
DB00945 Acetylsalicylic acid
DB00997 Doxorubicin
DB01076 Atorvastatin
DB01088 Iloprost
DB01095 Fluvastatin
DB01098 Rosuvastatin
DB01131 Proguanil
DB01157 Trimetrexate
DB01160 Dinoprost Tromethamine
DB01174 Phenobarbital
DB01213 Fomepizole
DB01466 Ethylmorphine
DB01536 4-Androstenedione
DB01561 Androstanedione
DB01586 Ursodeoxycholic acid
DB01689 Inhibitor Idd 384
DB01698 Rutin
DB01708 Dehydroepiandrosterone
DB01727 Isocitric Acid
DB01763 Tatp
DB01774 Adenosine-5'-Monophosphate Glucopyranosyl-Monophosphate Ester
DB01819 Phosphoenolpyruvate
DB01821 L-N(Omega)-Nitroarginine-2,4-L-Diaminobutyric Amide
DB01848 Isocitrate Calcium Complex
DB01907 Nicotinamide-Adenine-Dinucleotide
DB01942 Formic Acid
DB01992 Coenzyme A
DB01997 3-Bromo-7-Nitroindazole
DB02007 Alpha-D-Glucose-6-Phosphate
DB02015 Dihydrofolic Acid
DB02020 Alrestatin
DB02021 Fidarestat
DB02026 Furo[2,3d]Pyrimidine Antifolate
DB02027 N-{(4s)-4-Amino-5-[(2-Aminoethyl)Amino]Pentyl}-N'-Nitroguanidine
DB02044 N-(3-(Aminomethyl)Benzyl)Acetamidine
DB02056 (5e,13e)-9,15-Dihydroxy-11-Oxoprosta-5,13-Dien-1-Oicacid
DB02073 Biliverdine Ix Alpha
DB02077 L-N(Omega)-Nitroarginine-(4r)-Amino-L-Proline Amide
DB02101 Fidarestat(Stereoisomer)
DB02104 2,4-Diamino-5-Methyl-6-[(3,4,5-Trimethoxy-N-Methylanilino)Methyl]Pyrido[2,3-D]Pyrimidine
DB02132 [3-(4-Bromo-2-Fluoro-Benzyl)-7-Chloro-2,4-Dioxo-3,4-Dihydro-2h-Quinazolin-1-Yl]-Acetic Acid
DB02143 N-Isopropyl-N'-Hydroxyguanidine
DB02187 Equilin
DB02190 2-Oxalosuccinic Acid
DB02263 Glyceraldehyde-3-Phosphate
DB02266 Flufenamic Acid
DB02323 EM-1745
DB02329 Carbenoxolone
DB02338 Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate
DB02358 LY374571
DB02363 2'-Monophosphoadenosine-5'-Diphosphate
DB02383 Tolrestat
DB02427 2,4-Diamino-6-[N-(2',5'-Dimethoxybenzyl)-N-Methylamino]Quinazoline
DB02481 N-Benzylformamide
DB02518 N-Acetylalanine
DB02532 2,4,6-Triaminoquinazoline
DB02559 6-(Octahydro-1h-Indol-1-Ylmethyl)Decahydroquinazoline-2,4-Diamine
DB02583 N6-(2,5-Dimethoxy-Benzyl)-N6-Methyl-Pyrido[2,3-D]Pyrimidine-2,4,6-Triamine
DB02606 2-Butanol
DB02637 Oxaloacetate Ion
DB02644 N-Omega-Propyl-L-Arginine
DB02692 (6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin
DB02712 Sorbinil
DB02718 5-Formyl-6-Hydrofolic Acid
DB02721 4-Iodopyrazole
DB02727 N-Butyl-N'-Hydroxyguanidine
DB02831 Dihydrogenphosphate Ion
DB02834 IDD552
DB02897 Acetylphosphate
DB02901 Dihydrotestosterone
DB02919 2,4-Diamino-6-[N-(3',4',5'-Trimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine
DB02944 Alpha-D-Mannose
DB02991 S-Ethyl-N-[4-(Trifluoromethyl)Phenyl]Isothiourea
DB02994 Hydroxydimethylarsine Oxide
DB03014 Heme
DB03060 Sri-9662
DB03085 Hydroxyacetic Acid
DB03125 2,4-Diamino-5-(3,4,5-Trimethoxy-Benzyl)-Pyrimidin-1-Ium
DB03144 N-Omega-Hydroxy-L-Arginine
DB03147 Flavin-Adenine Dinucleotide
DB03169 (S)-Hmg-Coa
DB03247 Riboflavin Monophosphate
DB03351 Sri-9439
DB03431 Adenosine-5'-Diphosphate
DB03449 N-(4-(2-((3-Chlorophenylmethyl)Amino)Ethyl)Phenyl)-2-Thiophecarboxamidine
DB03461 2'-Monophosphoadenosine 5'-Diphosphoribose
DB03502 (4s)-4-{[(2s)-2-Amino-3-Oxopropyl]Sulfanyl}-L-Homoserinate
DB03581 Glucose-6-Phosphate
DB03625 5,10-Dideazatetrahydrofolic Acid
DB03695 6-(2,5-Dimethoxy-Benzyl)-5-Methyl-Pyrido[2,3-D]Pyrimidine-2,4-Diamine
DB03698 5-Mercaptoethanol-2-Decenoyl-Coenzyme A
DB03703 Cyclohexanol
DB03707 S-Ethyl-N-Phenyl-Isothiourea
DB03710 N5-(1-Imino-3-Butenyl)-L-Ornithine
DB03814 2-(N-Morpholino)-Ethanesulfonic Acid
DB03886 Biopterin
DB03892 5-N-Allyl-Arginine
DB03904 Urea
DB03987 2,4-Diamino-6-[N-(3',5'-Dimethoxybenzyl)-N-Methylamino]Pyrido[2,3-D]Pyrimidine
DB04066 Para-Coumaric Acid
DB04077 Glycerol
DB04105 N-Heptylformamide
DB04122 Beta-D-Glucose-6-Phosphate
DB04223 Nitroarginine
DB04272 Citric Acid
DB04275 N-Acetyl Serotonin
DB04279 3-Isopropylmalic Acid
DB04322 LY249543
DB04345 7,8-dimethylalloxazine
DB04363 Mesobiliverdin Iv Alpha
DB04377 3-Hydroxy-3-Methyl-Glutaric Acid
DB04398 Lactic Acid
DB04400 7,8-Dihydrobiopterin
DB04447 1,4-Dithiothreitol
DB04498 Aspartate Semialdehyde
DB04551 Fructose-1,6-Diphosphate
DB04557 Arachidonic Acid
DB04652 (11-BETA)-11,21-DIHYDROXY-PREGN-4-ENE-3,20-DIONE
DB04674 2-HYDROXY-3,5-DIIODOBENZOIC ACID
DB06693 Mevastatin
DB06813 Pralatrexate
DB06846 7-[3-(4-FLUORO-PHENYL)-1-ISOPROPYL-1H-INDOL-2-YL]-3,5-DIHYDROXY-HEPTANOIC ACID
DB06992 (3,3-dimethylpiperidin-1-yl)(6-(3-fluoro-4-methylphenyl)pyridin-2-yl)methanone
DB07017 (5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(1-hydroxy-1-methylethyl)-5-methyl-1,3-thiazol-4(5H)-one
DB07028 (2-{[(4-BROMO-2-FLUOROBENZYL)AMINO]CARBONYL}-5-CHLOROPHENOXY)ACETIC ACID
DB07030 (5-CHLORO-2-{[(3-NITROBENZYL)AMINO]CARBONYL}PHENOXY)ACETIC ACID
DB07049 (2R)-1-[(4-tert-butylphenyl)sulfonyl]-2-methyl-4-(4-nitrophenyl)piperazine
DB07056 2-(6-{[(3-chloro-2-methylphenyl)sulfonyl]amino}pyridin-2-yl)-N,N-diethylacetamide
DB07063 {3-[(4,5,7-TRIFLUORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-1H-INDOL-1-YL}ACETIC ACID
DB07093 {3-[(5-CHLORO-1,3-BENZOTHIAZOL-2-YL)METHYL]-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL}ACETIC ACID
DB07139 3-[5-(3-nitrophenyl)thiophen-2-yl]propanoic acid
DB07140 5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
DB07141 5-[(3R)-3-(5-methoxy-4'-methylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
DB07142 5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
DB07144 5-[(3R)-3-(5-methoxy-2',6'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
DB07177 (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID
DB07187 6-[(5-CHLORO-3-METHYL-1-BENZOFURAN-2-YL)SULFONYL]PYRIDAZIN-3(2H)-ONE
DB07262 1-{[N-(1-IMINO-GUANIDINO-METHYL)]SULFANYLMETHYL}-3-TRIFLUOROMETHYL-BENZENE
DB07310 (5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-methyl-5-(trifluoromethyl)-1,3-thiazol-4(5H)-one
DB07316 N-{1-[(1-carbamoylcyclopropyl)methyl]piperidin-4-yl}-N-cyclopropyl-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide
DB07450 2[4-BROMO-2-FLUOROPHENYL)METHYL]-6-FLUOROSPIRO[ISOQUINOLINE-4-(1H),3'-PYRROLIDINE]-1,2',3,5'(2H)-TETRONE
DB07498 4-[3-(3-NITROPHENYL)-1,2,4-OXADIAZOL-5-YL]BUTANOIC ACID
DB07619 N-cyclopropyl-N-(trans-4-pyridin-3-ylcyclohexyl)-4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]benzamide
DB07624 1-{[(3R)-3-methyl-4-({4-[(1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl]phenyl}sulfonyl)piperazin-1-yl]methyl}cyclopropanecarboxamide
DB07700 3-CARBOXAMIDO-1,3,5(10)-ESTRATRIEN-17(R)-SPIRO-2'(5',5'-DIMETHYL-6'OXO)TETRAHYDROPYRAN
DB07715 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE
DB07768 (10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE
DB07866 (5S)-2-(cyclooctylamino)-5-methyl-5-propyl-1,3-thiazol-4(5H)-one
DB07931 4-[(1R,2S)-1-ethyl-2-(4-hydroxyphenyl)butyl]phenol
DB07999 {4-[(CARBOXYMETHOXY)CARBONYL]-3,3-DIOXIDO-1-OXONAPHTHO[1,2-D]ISOTHIAZOL-2(1H)-YL}ACETIC ACID
DB08000 2-(CARBOXYMETHYL)-1-OXO-1,2-DIHYDRONAPHTHO[1,2-D]ISOTHIAZOLE-4-CARBOXYLIC ACID 3,3-DIOXIDE
DB08018 N-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE
DB08019 N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine
DB08084 IDD594
DB08098 {[5-(5-NITRO-2-FURYL)-1,3,4-OXADIAZOL-2-YL]THIO}ACETIC ACID
DB08234 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine
DB08277 2-(2-CHLORO-4-FLUOROPHENOXY)-2-METHYL-N-[(1R,2S,3S,5S,7S)-5-(METHYLSULFONYL)-2-ADAMANTYL]PROPANAMIDE
DB08280 (1S,3R,4S,5S,7S)-4-{[2-(4-METHOXYPHENOXY)-2-METHYLPROPANOYL]AMINO}ADAMANTANE-1-CARBOXAMIDE
DB08406 [N-(2,4-DIAMINOPTERIDIN-6-YL)-METHYL]-DIBENZ[B,F]AZEPINE
DB08448 (4aS)-5-[(2,4-diaminopteridin-6-yl)methyl]-4a,5-dihydro-2H-dibenzo[b,f]azepin-8-ol
DB08449 2-(3-((4,5,7-trifluorobenzo[d]thiazol-2-yl)methyl)-1H-pyrrolo[2,3-b]pyridin-1-yl)acetic acid
DB08604 TRICLOSAN
DB08605 6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL
DB08642 (2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamine
DB08771 (5R)-2-[(2-fluorophenyl)amino]-5-(1-methylethyl)-1,3-thiazol-4(5H)-one
DB08772 3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACID
DB08860 Pitavastatin
DB08878 Aminopterin
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