DT-Web

DB07177 - (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID


Identification
Name (5E,13E)-11-HYDROXY-9,15-DIOXOPROSTA-5,13-DIEN-1-OIC ACID
Accession Number DB07177
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 350.4492
Groups experimental
Monoisotopic Weight 350.20932407
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Prostaglandin reductase 1
Name Prostaglandin reductase 1
Gene Name PTGR1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.8329
Prostaglandin reductase 2
Name Prostaglandin reductase 2
Gene Name PTGR2
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.7008

Predictions


Id Partner name Gene Name Score
5488 PPH pph 0.1768
2369 Photoactive yellow protein pyp 0.154
96 Histidine ammonia-lyase HAL 0.1539
6257 Histidine ammonia-lyase Not Available 0.1539
6536 Histidine ammonia-lyase hutH 0.1539
6043 Putative G-protein coupled receptor 44 GPR44 0.0221
1313 Lactoylglutathione lyase GLO1 0.0189
2981 Phospholipase A2, membrane associated PLA2G2A 0.0176
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0174
6137 Multidrug resistance-associated protein 6 ABCC6 0.0146
6141 Sodium/bile acid cotransporter SLC10A1 0.0144
4604 Liver carboxylesterase 1 CES1 0.014
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0132
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0128
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0123
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0122
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0122
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0122
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0122
5332 MtdA bifunctional protein mtdA 0.0122
5322 Oxidoreductase ydhF ydhF 0.0122
4403 Protein iolS iolS 0.0122
5330 General stress protein 69 yhdN 0.0122
3778 NAD(P) transhydrogenase subunit beta pntB 0.0122
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0122
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0122
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0122
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0122
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.012
1024 Solute carrier family 22 member 11 SLC22A11 0.0116
6143 Solute carrier family 22 member 7 SLC22A7 0.0114
2164 Multidrug resistance-associated protein 4 ABCC4 0.0113
862 Multidrug resistance-associated protein 1 ABCC1 0.0108
2636 Shikimate dehydrogenase aroE 0.0106
3515 Shikimate dehydrogenase aroE 0.0106
5328 Prostaglandin F synthase Tb11.02.2310 0.0106
989 L-xylulose reductase DCXR 0.0106
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.0106
729 GDP-L-fucose synthetase TSTA3 0.0106
3463 GDP-L-fucose synthetase fcl 0.0106
3446 NADP-dependent alcohol dehydrogenase adh 0.0106
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0106
5073 Ferredoxin--NADP reductase petH 0.0106
5076 Ferredoxin--NADP reductase fpr 0.0106
5119 Ferredoxin--NADP reductase petH 0.0106
5121 Ferredoxin--NADP reductase fpr 0.0106
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0106
4582 Putative pteridine reductase 2 ptr2 0.0106
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0106
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0106
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0106
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0106
2286 Isocitrate dehydrogenase [NADP] icd 0.0106
2302 Isocitrate dehydrogenase [NADP] icd 0.0106
2771 Isocitrate dehydrogenase [NADP] icd 0.0106
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0106
290 Prostaglandin G/H synthase 2 PTGS2 0.0105
6142 Solute carrier family 22 member 8 SLC22A8 0.0101
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0099
20 Prostaglandin G/H synthase 1 PTGS1 0.0099
4531 Putative ketoacyl reductase actIII 0.0098
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.0098
3062 Aspartate-semialdehyde dehydrogenase asd 0.0098
2675 Pteridine reductase 1 PTR1 0.0093
587 Serum albumin ALB 0.0092
1124 Sepiapterin reductase SPR 0.0092
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0092
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0092
1729 Solute carrier family 22 member 6 SLC22A6 0.0092
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0089
666 NADP-dependent malic enzyme ME1 0.0089
646 Malate dehydrogenase, cytoplasmic MDH1 0.0088
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0087
2159 Quinone oxidoreductase CRYZ 0.0086
6016 Cytochrome P450 2C19 CYP2C19 0.008
1588 Multidrug resistance protein 1 ABCB1 0.0077
4757 Cytochrome P450 2C9 CYP2C9 0.0077
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0076
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0076
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0076
654 Flavin reductase BLVRB 0.0075
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.007
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0069
444 Alcohol dehydrogenase 1B ADH1B 0.0068
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0066
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0066
76 Nitric-oxide synthase, brain NOS1 0.0062
822 Aldose reductase AKR1B1 0.0061
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0057
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0057
365 Dihydrofolate reductase DHFR 0.0057
2381 Dihydrofolate reductase DFR1 0.0057
2833 Dihydrofolate reductase Not Available 0.0057
2931 Dihydrofolate reductase folA 0.0057
3544 Dihydrofolate reductase folA 0.0057
3682 Dihydrofolate reductase folA 0.0057
6642 Dihydrofolate reductase folA 0.0057
6756 Dihydrofolate reductase dfrA 0.0057
4120 NADPH--cytochrome P450 reductase POR 0.0055
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