DT-Web

DB02637 - Oxaloacetate Ion


Identification
Name Oxaloacetate Ion
Accession Number DB02637 (EXPT02406)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 131.0636
Groups experimental
Monoisotopic Weight 130.998048206
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Citrate synthase, mitochondrial
Name Citrate synthase, mitochondrial
Gene Name CS
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Malate dehydrogenase
Name Malate dehydrogenase
Gene Name mdh
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.0054
Sepiapterin reductase
Name Sepiapterin reductase
Gene Name SPR
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.526
Methylmalonyl-CoA carboxyltransferase 5S subunit
Name Methylmalonyl-CoA carboxyltransferase 5S subunit
Gene Name Not Available
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.1859
Citrate lyase beta subunit-like protein
Name Citrate lyase beta subunit-like protein
Gene Name DR_1240
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.0619

Predictions


Id Partner name Gene Name Score
4514 Citrate lyase beta subunit-like protein citE 1.0619
2518 1-aminocyclopropane-1-carboxylate deaminase acdS 0.247
365 Dihydrofolate reductase DHFR 0.1357
2381 Dihydrofolate reductase DFR1 0.1357
2833 Dihydrofolate reductase Not Available 0.1357
2931 Dihydrofolate reductase folA 0.1357
3544 Dihydrofolate reductase folA 0.1357
3682 Dihydrofolate reductase folA 0.1357
6642 Dihydrofolate reductase folA 0.1357
6756 Dihydrofolate reductase dfrA 0.1357
3168 Beta-lactamase OXA-1 bla 0.0372
3230 Non-ATP-dependent L-selective hydantoinase lhyD 0.0372
4819 Hydrolase Not Available 0.0372
5249 Hydrolase Not Available 0.0372
5436 Hydrolase Not Available 0.0372
3122 D-hydantoinase Not Available 0.0372
3145 D-hydantoinase hyuA 0.0372
3292 Alanine racemase, catabolic dadX 0.0324
3281 Isoaspartyl dipeptidase iadA 0.0324
4264 Alpha-L-fucosidase, putative TM_0306 0.0324
3237 Beta-lactamase OXA-2 bla 0.0324
2801 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase murE 0.0299
4549 Endonuclease III HP_0602 0.0282
2646 Dihydroorotase pyrC 0.0282
2717 Folylpolyglutamate synthase fgs 0.027
2340 Beta-lactamase PSE-2 bla 0.0255
2796 Parathion hydrolase opd 0.0252
6539 Parathion hydrolase opd 0.0252
894 Alanine racemase alr 0.0246
2453 Alanine racemase alr 0.0246
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.024
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0144
2240 Cell division protein kinase 2 CDK2 0.0139
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0126
646 Malate dehydrogenase, cytoplasmic MDH1 0.0121
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0106
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0097
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0097
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0097
5322 Oxidoreductase ydhF ydhF 0.0097
5330 General stress protein 69 yhdN 0.0097
3778 NAD(P) transhydrogenase subunit beta pntB 0.0097
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0097
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0097
5332 MtdA bifunctional protein mtdA 0.0097
4403 Protein iolS iolS 0.0097
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0097
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0097
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0096
444 Alcohol dehydrogenase 1B ADH1B 0.0095
2636 Shikimate dehydrogenase aroE 0.0084
3515 Shikimate dehydrogenase aroE 0.0084
989 L-xylulose reductase DCXR 0.0084
4582 Putative pteridine reductase 2 ptr2 0.0084
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0084
729 GDP-L-fucose synthetase TSTA3 0.0084
3463 GDP-L-fucose synthetase fcl 0.0084
3446 NADP-dependent alcohol dehydrogenase adh 0.0084
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0084
5073 Ferredoxin--NADP reductase petH 0.0084
5076 Ferredoxin--NADP reductase fpr 0.0084
5119 Ferredoxin--NADP reductase petH 0.0084
5121 Ferredoxin--NADP reductase fpr 0.0084
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0084
5328 Prostaglandin F synthase Tb11.02.2310 0.0084
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0084
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0084
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.0084
2286 Isocitrate dehydrogenase [NADP] icd 0.0084
2302 Isocitrate dehydrogenase [NADP] icd 0.0084
2771 Isocitrate dehydrogenase [NADP] icd 0.0084
4531 Putative ketoacyl reductase actIII 0.0078
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.0078
3062 Aspartate-semialdehyde dehydrogenase asd 0.0078
6297 Prostaglandin reductase 1 PTGR1 0.0078
2675 Pteridine reductase 1 PTR1 0.0073
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0073
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.007
666 NADP-dependent malic enzyme ME1 0.007
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0069
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.0069
4428 Redox-sensing transcriptional repressor rex rex 0.0069
4449 ADP-ribosyltransferase Not Available 0.0069
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.0069
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.0069
4472 Glucose 1-dehydrogenase Not Available 0.0069
4487 Transcriptional regulator nadR nadR 0.0069
3729 Citrate synthase gltA 0.0069
4575 Citrate synthase cit 0.0069
4580 Citrate synthase gltA 0.0069
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.0069
4443 Quinate/shikimate dehydrogenase ydiB 0.0069
4502 Formate dehydrogenase Not Available 0.0069
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.0069
4500 L-lactate dehydrogenase 2 ldh2 0.0069
4447 Hypothetical protein yhfP yhfP 0.0069
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.0069
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.0069
3381 Alcohol dehydrogenase Not Available 0.0069
4508 Alcohol dehydrogenase adhA 0.0069
4414 Dehydrogenase TT_P0035 0.0069
2350 3-isopropylmalate dehydrogenase leuB 0.0069
3092 3-isopropylmalate dehydrogenase leuB 0.0069
4471 CDP-D-glucose-4,6-dehydratase ascB 0.0069
4418 AGR_L_3209p AGR_L_3209 0.0069
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.0069
4455 Glycerol dehydrogenase gldA 0.0069
4497 Benzyl alcohol dehydrogenase xylB 0.0069
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.0069
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.0069
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0069
3726 D-3-phosphoglycerate dehydrogenase serA 0.0069
4291 D-3-phosphoglycerate dehydrogenase serA 0.0069
4435 L-aspartate dehydrogenase nadX 0.0069
4467 Alpha-glucosidase, putative TM_0752 0.0069
4423 Levodione reductase lvr 0.0069
4507 Alanine dehydrogenase ald 0.0069
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.0069
4451 Vip2Ac vip2Ac 0.0069
2159 Quinone oxidoreductase CRYZ 0.0068
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.006
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.006
4486 Phenol 2-hydroxylase component B pheA2 0.006
2336 2,3-diketo-L-gulonate reductase dlgD 0.006
3081 3-dehydroquinate synthase aroB 0.006
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.006
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.006
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.006
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.006
4509 Acetoin(diacetyl) reductase budC 0.006
2538 6-phospho-beta-glucosidase bglT bglT 0.006
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.006
2424 L-lactate dehydrogenase ldh 0.006
2641 L-lactate dehydrogenase Not Available 0.006
4437 L-lactate dehydrogenase ldh 0.006
4442 L-lactate dehydrogenase ldh 0.006
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.006
126 D-lactate dehydrogenase dld 0.006
3545 D-lactate dehydrogenase Not Available 0.006
4510 D-lactate dehydrogenase ldhA 0.006
4427 TDP-glucose-4,6-dehydratase desIV 0.006
2967 CDP-paratose 2-epimerase rfbE 0.006
4498 Ornithine cyclodeaminase PP3533 0.006
3177 dTDP-glucose 4,6-dehydratase rfbB 0.006
4499 dTDP-glucose 4,6-dehydratase rmlB 0.006
2018 Deoxyhypusine synthase DHPS 0.006
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.006
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.006
4482 UDP-galactose 4-epimerase galE 0.006
3615 Dihydrodipicolinate reductase dapB 0.006
3618 Dihydrodipicolinate reductase dapB 0.006
4462 Dihydrodipicolinate reductase dapB 0.006
4439 Ferredoxin reductase bphA4 0.006
4503 NADPH-flavin oxidoreductase frp 0.006
4496 C-terminal-binding protein 1 CTBP1 0.006
4450 Iota toxin component Ia Not Available 0.006
4477 Dihydrolipoyl dehydrogenase lpdV 0.006
5077 Dihydrolipoyl dehydrogenase Not Available 0.006
5117 Dihydrolipoyl dehydrogenase lpd 0.006
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.006
2591 Urocanate hydratase hutU 0.006
2507 Diphtheria toxin Not Available 0.006
2393 Maltose-6'-phosphate glucosidase glvA 0.006
3401 D-2-hydroxyisocaproate dehydrogenase Not Available 0.006
654 Flavin reductase BLVRB 0.0059
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0056
2683 Mono-ADP-ribosyltransferase C3 C3 0.0055
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.0055
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.0055
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0055
3367 GDP-mannose 6-dehydrogenase algD 0.0055
4318 Siroheme synthase cysG 0.0055
4343 Alpha-glucosidase aglA 0.0055
4504 WbpP Not Available 0.0055
711 UDP-glucose 6-dehydrogenase UGDH 0.0055
3672 UDP-glucose 6-dehydrogenase hasB 0.0055
4440 NADH peroxidase npr 0.0055
63 Malate dehydrogenase mdh 0.0054
2329 Malate dehydrogenase mdh 0.0054
4420 Malate dehydrogenase mdh 0.0054
4438 Malate dehydrogenase mdh 0.0054
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0054
816 Biliverdin reductase A BLVRA 0.0054
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0054
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0054
4476 Mannitol dehydrogenase mtlD 0.0054
2434 NH(3)-dependent NAD(+) synthetase nadE 0.0052
2910 NH(3)-dependent NAD(+) synthetase nadE 0.0052
3217 NH(3)-dependent NAD(+) synthetase nadE 0.0052
2617 Nitric oxide synthase oxygenase nos 0.0052
2701 Nitric oxide synthase oxygenase nos 0.0052
2826 Glucose--fructose oxidoreductase gfo 0.0052
3191 Histidinol dehydrogenase hisD 0.0052
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.0052
3070 Adenosylhomocysteinase AHCY 0.0052
4424 Adenosylhomocysteinase PFE1050w 0.0052
6278 Adenosylhomocysteinase ahcY 0.0052
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0052
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0052
327 Glutathione reductase gor 0.0052
5110 Glutathione reductase GR2 0.0052
597 Dihydropteridine reductase QDPR 0.0052
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0052
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0052
328 Sorbitol dehydrogenase SORD 0.0052
396 Alcohol dehydrogenase 4 ADH4 0.0052
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0052
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0052
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0052
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.005
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.005
12 Alcohol dehydrogenase class 3 ADH5 0.005
77 L-lactate dehydrogenase B chain LDHB 0.005
76 Nitric-oxide synthase, brain NOS1 0.0049
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0049
822 Aldose reductase AKR1B1 0.0048
4491 DNA ligase, NAD-dependent ligA 0.0048
473 L-lactate dehydrogenase A chain LDHA 0.0048
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0048
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0048
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0048
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0048
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0048
2762 UDP-glucose 4-epimerase GALE 0.0047
3461 UDP-glucose 4-epimerase galE 0.0047
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0047
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0045
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0045
569 Retinal dehydrogenase 2 ALDH1A2 0.0044
611 Retinal dehydrogenase 1 ALDH1A1 0.0044
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0044
251 Alcohol dehydrogenase 1A ADH1A 0.0043
4120 NADPH--cytochrome P450 reductase POR 0.0043
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0042
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0039
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0039
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0039
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0039
714 Glutathione reductase, mitochondrial GSR 0.0039
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0038
517 Alcohol dehydrogenase 1C ADH1C 0.0037
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