DT-Web

DB02323 - EM-1745


Identification
Name EM-1745
Accession Number DB02323 (EXPT01802)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 677.8301
Groups experimental
Monoisotopic Weight 677.378849011
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Estradiol 17-beta-dehydrogenase 1
Name Estradiol 17-beta-dehydrogenase 1
Gene Name HSD17B1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.6071

Predictions


Id Partner name Gene Name Score
2972 6-deoxyerythronolide B hydroxylase eryF 0.0493
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.0457
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0418
2268 Cholesterol oxidase choB 0.0331
2822 Cholesterol oxidase choA 0.0331
2283 Steroid Delta-isomerase ksi 0.0305
2920 Steroid Delta-isomerase ksi 0.0305
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0286
1050 Bile salt sulfotransferase SULT2A1 0.0252
380 Cytochrome P450 17A1 CYP17A1 0.0227
756 Sex hormone-binding globulin SHBG 0.0203
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.017
146 Androgen receptor AR 0.0164
3811 Cytochrome P450 19A1 CYP19A1 0.0144
6107 Cytochrome P450 3A7 CYP3A7 0.0109
1588 Multidrug resistance protein 1 ABCB1 0.0095
4512 Cytochrome P450 3A4 CYP3A4 0.0084
646 Malate dehydrogenase, cytoplasmic MDH1 0.0064
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0059
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0055
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.005
666 NADP-dependent malic enzyme ME1 0.005
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0049
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0048
444 Alcohol dehydrogenase 1B ADH1B 0.0047
5330 General stress protein 69 yhdN 0.0045
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0045
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0045
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0045
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0045
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0045
4403 Protein iolS iolS 0.0045
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0045
5332 MtdA bifunctional protein mtdA 0.0045
3778 NAD(P) transhydrogenase subunit beta pntB 0.0045
5322 Oxidoreductase ydhF ydhF 0.0045
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0045
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0044
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0041
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.004
654 Flavin reductase BLVRB 0.004
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0039
5073 Ferredoxin--NADP reductase petH 0.0039
5076 Ferredoxin--NADP reductase fpr 0.0039
5119 Ferredoxin--NADP reductase petH 0.0039
5121 Ferredoxin--NADP reductase fpr 0.0039
4582 Putative pteridine reductase 2 ptr2 0.0039
989 L-xylulose reductase DCXR 0.0039
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0039
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0039
2636 Shikimate dehydrogenase aroE 0.0039
3515 Shikimate dehydrogenase aroE 0.0039
3446 NADP-dependent alcohol dehydrogenase adh 0.0039
5328 Prostaglandin F synthase Tb11.02.2310 0.0039
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0039
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0039
2286 Isocitrate dehydrogenase [NADP] icd 0.0039
2302 Isocitrate dehydrogenase [NADP] icd 0.0039
2771 Isocitrate dehydrogenase [NADP] icd 0.0039
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0038
6297 Prostaglandin reductase 1 PTGR1 0.0036
4531 Putative ketoacyl reductase actIII 0.0036
3062 Aspartate-semialdehyde dehydrogenase asd 0.0036
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.0036
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0034
2675 Pteridine reductase 1 PTR1 0.0034
2159 Quinone oxidoreductase CRYZ 0.0034
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0034
1124 Sepiapterin reductase SPR 0.0034
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0032
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0032
822 Aldose reductase AKR1B1 0.0031
816 Biliverdin reductase A BLVRA 0.0031
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0031
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0031
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0031
365 Dihydrofolate reductase DHFR 0.0029
2381 Dihydrofolate reductase DFR1 0.0029
2833 Dihydrofolate reductase Not Available 0.0029
2931 Dihydrofolate reductase folA 0.0029
3544 Dihydrofolate reductase folA 0.0029
3682 Dihydrofolate reductase folA 0.0029
6642 Dihydrofolate reductase folA 0.0029
6756 Dihydrofolate reductase dfrA 0.0029
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0028
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0028
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0028
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0028
396 Alcohol dehydrogenase 4 ADH4 0.0028
328 Sorbitol dehydrogenase SORD 0.0028
597 Dihydropteridine reductase QDPR 0.0028
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0028
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0027
77 L-lactate dehydrogenase B chain LDHB 0.0027
12 Alcohol dehydrogenase class 3 ADH5 0.0027
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0026
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0026
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0026
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0026
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0026
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0026
473 L-lactate dehydrogenase A chain LDHA 0.0026
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0024
569 Retinal dehydrogenase 2 ALDH1A2 0.0024
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0023
611 Retinal dehydrogenase 1 ALDH1A1 0.0023
4120 NADPH--cytochrome P450 reductase POR 0.0023
76 Nitric-oxide synthase, brain NOS1 0.0023
251 Alcohol dehydrogenase 1A ADH1A 0.0022
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0022
4423 Levodione reductase lvr 0.0021
4428 Redox-sensing transcriptional repressor rex rex 0.0021
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.0021
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.0021
4447 Hypothetical protein yhfP yhfP 0.0021
4449 ADP-ribosyltransferase Not Available 0.0021
2350 3-isopropylmalate dehydrogenase leuB 0.0021
3092 3-isopropylmalate dehydrogenase leuB 0.0021
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.0021
4507 Alanine dehydrogenase ald 0.0021
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.0021
4497 Benzyl alcohol dehydrogenase xylB 0.0021
4435 L-aspartate dehydrogenase nadX 0.0021
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.0021
4472 Glucose 1-dehydrogenase Not Available 0.0021
4418 AGR_L_3209p AGR_L_3209 0.0021
4443 Quinate/shikimate dehydrogenase ydiB 0.0021
4500 L-lactate dehydrogenase 2 ldh2 0.0021
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.0021
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.0021
3381 Alcohol dehydrogenase Not Available 0.0021
4508 Alcohol dehydrogenase adhA 0.0021
4414 Dehydrogenase TT_P0035 0.0021
4455 Glycerol dehydrogenase gldA 0.0021
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.0021
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.0021
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.0021
4502 Formate dehydrogenase Not Available 0.0021
4487 Transcriptional regulator nadR nadR 0.0021
3729 Citrate synthase gltA 0.0021
4575 Citrate synthase cit 0.0021
4580 Citrate synthase gltA 0.0021
4471 CDP-D-glucose-4,6-dehydratase ascB 0.0021
4451 Vip2Ac vip2Ac 0.0021
4467 Alpha-glucosidase, putative TM_0752 0.0021
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.0021
714 Glutathione reductase, mitochondrial GSR 0.002
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0019
517 Alcohol dehydrogenase 1C ADH1C 0.0019
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0017
3177 dTDP-glucose 4,6-dehydratase rfbB 0.0017
4499 dTDP-glucose 4,6-dehydratase rmlB 0.0017
4427 TDP-glucose-4,6-dehydratase desIV 0.0017
4439 Ferredoxin reductase bphA4 0.0017
4486 Phenol 2-hydroxylase component B pheA2 0.0017
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.0017
4477 Dihydrolipoyl dehydrogenase lpdV 0.0017
5077 Dihydrolipoyl dehydrogenase Not Available 0.0017
5117 Dihydrolipoyl dehydrogenase lpd 0.0017
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.0017
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.0017
2967 CDP-paratose 2-epimerase rfbE 0.0017
4482 UDP-galactose 4-epimerase galE 0.0017
2538 6-phospho-beta-glucosidase bglT bglT 0.0017
2393 Maltose-6'-phosphate glucosidase glvA 0.0017
4509 Acetoin(diacetyl) reductase budC 0.0017
3081 3-dehydroquinate synthase aroB 0.0017
2507 Diphtheria toxin Not Available 0.0017
4503 NADPH-flavin oxidoreductase frp 0.0017
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.0017
4450 Iota toxin component Ia Not Available 0.0017
3615 Dihydrodipicolinate reductase dapB 0.0017
3618 Dihydrodipicolinate reductase dapB 0.0017
4462 Dihydrodipicolinate reductase dapB 0.0017
2591 Urocanate hydratase hutU 0.0017
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.0017
4498 Ornithine cyclodeaminase PP3533 0.0017
2424 L-lactate dehydrogenase ldh 0.0017
2641 L-lactate dehydrogenase Not Available 0.0017
4437 L-lactate dehydrogenase ldh 0.0017
4442 L-lactate dehydrogenase ldh 0.0017
126 D-lactate dehydrogenase dld 0.0017
3545 D-lactate dehydrogenase Not Available 0.0017
4510 D-lactate dehydrogenase ldhA 0.0017
2018 Deoxyhypusine synthase DHPS 0.0017
2336 2,3-diketo-L-gulonate reductase dlgD 0.0017
3401 D-2-hydroxyisocaproate dehydrogenase Not Available 0.0017
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0017
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0017
4496 C-terminal-binding protein 1 CTBP1 0.0017
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.0017
2683 Mono-ADP-ribosyltransferase C3 C3 0.0016
4504 WbpP Not Available 0.0015
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.0015
3367 GDP-mannose 6-dehydrogenase algD 0.0015
4318 Siroheme synthase cysG 0.0015
4440 NADH peroxidase npr 0.0015
4343 Alpha-glucosidase aglA 0.0015
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.0015
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0015
63 Malate dehydrogenase mdh 0.0015
2329 Malate dehydrogenase mdh 0.0015
3445 Malate dehydrogenase mdh 0.0015
4420 Malate dehydrogenase mdh 0.0015
4438 Malate dehydrogenase mdh 0.0015
4476 Mannitol dehydrogenase mtlD 0.0015
2617 Nitric oxide synthase oxygenase nos 0.0015
2701 Nitric oxide synthase oxygenase nos 0.0015
206 3-keto-steroid reductase HSD17B7 0.0015
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.0015
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.0015
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.0015
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.0015
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.0015
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.0015
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.0015
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.0015
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.0015
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.0015
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.0015
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.0015
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.0015
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.0015
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.0015
602 Acyl carrier protein, mitochondrial NDUFAB1 0.0015
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.0015
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.0015
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.0015
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.0015
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.0015
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.0015
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.0015
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.0015
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.0015
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.0015
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.0015
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.0015
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.0015
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.0015
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.0015
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.0015
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.0015
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.0015
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.0015
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.0015
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.0015
107 C-4 methylsterol oxidase SC4MOL 0.0015
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.0015
729 GDP-L-fucose synthetase TSTA3 0.0015
3463 GDP-L-fucose synthetase fcl 0.0015
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.0015
644 Heme oxygenase 2 HMOX2 0.0015
4982 Heme oxygenase 2 pbsA2 0.0015
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.0015
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.0015
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.0015
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.0015
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.0015
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.0015
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.0015
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.0015
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.0014
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.0014
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.0014
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.0014
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.0014
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.0014
34 7-dehydrocholesterol reductase DHCR7 0.0014
662 Fatty aldehyde dehydrogenase ALDH3A2 0.0014
711 UDP-glucose 6-dehydrogenase UGDH 0.0014
3672 UDP-glucose 6-dehydrogenase hasB 0.0014
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.0014
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.0014
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0014
3726 D-3-phosphoglycerate dehydrogenase serA 0.0014
4291 D-3-phosphoglycerate dehydrogenase serA 0.0014
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.0014
167 L-lactate dehydrogenase C chain LDHC 0.0014
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.0014
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.0014
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.0014
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.0014
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.0014
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.0014
643 Peroxisomal bifunctional enzyme EHHADH 0.0014
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.0014
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.0014
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.0014
2434 NH(3)-dependent NAD(+) synthetase nadE 0.0014
2910 NH(3)-dependent NAD(+) synthetase nadE 0.0014
3217 NH(3)-dependent NAD(+) synthetase nadE 0.0014
2826 Glucose--fructose oxidoreductase gfo 0.0014
3070 Adenosylhomocysteinase AHCY 0.0014
4424 Adenosylhomocysteinase PFE1050w 0.0014
6278 Adenosylhomocysteinase ahcY 0.0014
3191 Histidinol dehydrogenase hisD 0.0014
327 Glutathione reductase gor 0.0014
5110 Glutathione reductase GR2 0.0014
857 Malate dehydrogenase, mitochondrial MDH2 0.0014
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0014
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0013
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.0013
4491 DNA ligase, NAD-dependent ligA 0.0013
2762 UDP-glucose 4-epimerase GALE 0.0013
3461 UDP-glucose 4-epimerase galE 0.0013
6026 Alcohol dehydrogenase 6 ADH6 0.0012
627 11-cis retinol dehydrogenase RDH5 0.0012
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0012
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0012
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0012
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0012
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0012
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0012
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0012
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0012
13 Aminomethyltransferase, mitochondrial AMT 0.0012
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0012
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0012
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0012
626 Cysteine dioxygenase type 1 CDO1 0.0012
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0012
810 Heme oxygenase 1 HMOX1 0.0011
3391 Heme oxygenase 1 pbsA1 0.0011
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.001
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.001
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.001
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.001
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.001
279 Tyrosinase TYR 0.001
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.001
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.001
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0009
468 Cytochrome P450 4A11 CYP4A11 0.0008
6020 Aldehyde oxidase AOX1 0.0008
3947 Xanthine dehydrogenase/oxidase XDH 0.0007
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