DT-Web

DB00898 - Ethanol


Identification
Name Ethanol
Accession Number DB00898 (APRD00738)
Type small molecule
Description A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in alcoholic beverages. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 46.0684
Groups approved
Monoisotopic Weight 46.041864814
Pharmacology
Indication For therapeutic neurolysis of nerves or ganglia for the relief of intractable chronic pain in such conditions as inoperable cancer and trigeminal neuralgia (tic douloureux), in patients for whom neurosurgical procedures are contraindicated.
Mechanism of action Ethanol affects the brain's neurons in several ways. It alters their membranes as well as their ion channels, enzymes, and receptors. Alcohol also binds directly to the receptors for acetylcholine, serotonin, GABA, and the NMDA receptors for glutamate. The sedative effects of ethanol are mediated through binding to GABA receptors and glycine receptors (alpha 1 and alpha 2 subunits). It also inhibits NMDA receptor functioning. In its role as an anti-infective, ethanol acts as an osmolyte or dehydrating agent that disrupts the osmotic balance across cell membranes.
Absorption Rapidly absorbed.
Protein binding Not Available
Biotransformation Hepatic. Metabolized by cytochrome P450 enzyme CYP2E1.
Route of elimination Not Available
Toxicity Oral, rat LD50: 5628 mg/kg. Symptoms and effects of overdose include nausea, vomiting, CNS depression, acute respiratory failure or death and with chronic use, severe health problems, such as liver and brain damage.
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions
Drug Mechanism of interaction
Abacavir Abacavir is partly metabolized through the alcohol dehydrogenase enzyme system. Alcohol increases the area under the curve (about 41%) of Abacavir. Interaction does not appear to be clinically significant.
gabapentin enacarbil Avoid combination due to ethanol induced increased absorption of gabapentin enacarbil and increased CNS depression.
Mipomersen The combination of these drugs will likely enhance mipomersen related hepatotoxicity. Therefore patients using both these drugs, should limit their alcohol to a daily maximum of 1 drink (or equivalent).
Perampanel Avoid combination due to the enhanced central nervous system depression, and likely worse behavioral and psychiatric adverse reactions.
Tizanidine Ethanol increases the adverse effects of Tizanidine. The CNS depressant effects of these agents are additive.
Triprolidine Triprolidine may enhance the CNS depressant effects of Ethanol.
Food Interactions Not Available

Targets


Gamma-aminobutyric-acid receptor subunit alpha-1
Name Gamma-aminobutyric-acid receptor subunit alpha-1
Gene Name GABRA1
Pharmacological action yes
Actions agonist
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Santhakumar V, Wallner M, Otis TS: Ethanol acts directly on extrasynaptic subtypes of GABAA receptors to increase tonic inhibition. Alcohol. 2007 May;41(3):211-21. - Pubmed
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
  • Earl DE, Tietz EI: Inhibition of recombinant L-type voltage-gated calcium channels by positive allosteric modulators of {gamma}-aminobutyric acid type A receptors. J Pharmacol Exp Ther. 2011 Jan 24. - Pubmed
DTHybrid score 0.3523
Glutamate [NMDA] receptor subunit 3A
Name Glutamate [NMDA] receptor subunit 3A
Gene Name GRIN3A
Pharmacological action yes
Actions antagonist
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Wang J, Lanfranco MF, Gibb SL, Ron D: Ethanol-mediated long-lasting adaptations of the NR2B-containing NMDA receptors in the dorsomedial striatum. Channels (Austin). 2011 Jul 1;5(4). - Pubmed
  • Ron D, Wang J: The NMDA Receptor and Alcohol Addiction - Pubmed
  • Williams K: Extracellular Modulation of NMDA Receptors - Pubmed
  • Xu M, Thetford Smothers C, Woodward JJ: Effects of ethanol on phosphorylation site mutants of recombinant N-methyl-d-aspartate receptors. Alcohol. 2010 Dec 14. - Pubmed
DTHybrid score 0.2947
Glycine receptor subunit alpha-1
Name Glycine receptor subunit alpha-1
Gene Name GLRA1
Pharmacological action yes
Actions agonist
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Fuentealba J, Munoz B, Yevenes G, Moraga-Cid G, Perez C, Guzman L, Rigo JM, Aguayo LG: Potentiation and inhibition of glycine receptors by tutin. Neuropharmacology. 2011 Feb-Mar;60(2-3):453-9. Epub 2010 Oct 31. - Pubmed
  • Baenziger JE, Corringer PJ: 3D structure and allosteric modulation of the transmembrane domain of pentameric ligand-gated ion channels. Neuropharmacology. 2011 Jan;60(1):116-25. Epub 2010 Aug 14. - Pubmed
  • Ye Q, Koltchine VV, Mihic SJ, Mascia MP, Wick MJ, Finn SE, Harrison NL, Harris RA: Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267. J Biol Chem. 1998 Feb 6;273(6):3314-9. - Pubmed
DTHybrid score 0.315
Glycine receptor subunit alpha-2
Name Glycine receptor subunit alpha-2
Gene Name GLRA2
Pharmacological action yes
Actions agonist
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Ye Q, Koltchine VV, Mihic SJ, Mascia MP, Wick MJ, Finn SE, Harrison NL, Harris RA: Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267. J Biol Chem. 1998 Feb 6;273(6):3314-9. - Pubmed
  • Baenziger JE, Corringer PJ: 3D structure and allosteric modulation of the transmembrane domain of pentameric ligand-gated ion channels. Neuropharmacology. 2011 Jan;60(1):116-25. Epub 2010 Aug 14. - Pubmed
DTHybrid score 0.2696
Alcohol dehydrogenase 1A
Name Alcohol dehydrogenase 1A
Gene Name ADH1A
Pharmacological action yes
Actions agonist
References
  • Hernandez-Tobias A, Julian-Sanchez A, Pina E, Riveros-Rosas H: Natural alcohol exposure: Is ethanol the main substrate for alcohol dehydrogenases in animals? Chem Biol Interact. 2011 Feb 14. - Pubmed
  • Matsumoto M, Cyganek I, Sanghani PC, Cho WK, Liangpunsakul S, Crabb DW: Ethanol metabolism by HeLa cells transduced with human alcohol dehydrogenase isoenzymes: control of the pathway by acetaldehyde concentration. Alcohol Clin Exp Res. 2011 Jan;35(1):28-38. - Pubmed
  • Nishimura FT, Kimura Y, Abe S, Fukunaga T, Saijoh K: Effects of polymorphisms in untranslated regions of the class I alcohol dehydrogenase (ADH) genes on alcohol metabolism in Japanese subjects and transcriptional activity in HepG2 cells. Nihon Arukoru Yakubutsu Igakkai Zasshi. 2009 Jun;44(3):139-55. - Pubmed
  • Jelski W, Kozlowski M, Laudanski J, Niklinski J, Szmitkowski M: The activity of class I, II, III, and IV alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) in esophageal cancer. Dig Dis Sci. 2009 Apr;54(4):725-30. Epub 2008 Aug 9. - Pubmed
DTHybrid score 0.6114
Alcohol dehydrogenase 1B
Name Alcohol dehydrogenase 1B
Gene Name ADH1B
Pharmacological action yes
Actions agonist
References
  • Hernandez-Tobias A, Julian-Sanchez A, Pina E, Riveros-Rosas H: Natural alcohol exposure: Is ethanol the main substrate for alcohol dehydrogenases in animals? Chem Biol Interact. 2011 Feb 14. - Pubmed
  • Matsumoto M, Cyganek I, Sanghani PC, Cho WK, Liangpunsakul S, Crabb DW: Ethanol metabolism by HeLa cells transduced with human alcohol dehydrogenase isoenzymes: control of the pathway by acetaldehyde concentration. Alcohol Clin Exp Res. 2011 Jan;35(1):28-38. - Pubmed
  • Nishimura FT, Kimura Y, Abe S, Fukunaga T, Saijoh K: Effects of polymorphisms in untranslated regions of the class I alcohol dehydrogenase (ADH) genes on alcohol metabolism in Japanese subjects and transcriptional activity in HepG2 cells. Nihon Arukoru Yakubutsu Igakkai Zasshi. 2009 Jun;44(3):139-55. - Pubmed
  • Jelski W, Kozlowski M, Laudanski J, Niklinski J, Szmitkowski M: The activity of class I, II, III, and IV alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) in esophageal cancer. Dig Dis Sci. 2009 Apr;54(4):725-30. Epub 2008 Aug 9. - Pubmed
DTHybrid score 0.835
Alcohol dehydrogenase 1C
Name Alcohol dehydrogenase 1C
Gene Name ADH1C
Pharmacological action yes
Actions agonist
References
  • Hernandez-Tobias A, Julian-Sanchez A, Pina E, Riveros-Rosas H: Natural alcohol exposure: Is ethanol the main substrate for alcohol dehydrogenases in animals? Chem Biol Interact. 2011 Feb 14. - Pubmed
  • Matsumoto M, Cyganek I, Sanghani PC, Cho WK, Liangpunsakul S, Crabb DW: Ethanol metabolism by HeLa cells transduced with human alcohol dehydrogenase isoenzymes: control of the pathway by acetaldehyde concentration. Alcohol Clin Exp Res. 2011 Jan;35(1):28-38. - Pubmed
  • Nishimura FT, Kimura Y, Abe S, Fukunaga T, Saijoh K: Effects of polymorphisms in untranslated regions of the class I alcohol dehydrogenase (ADH) genes on alcohol metabolism in Japanese subjects and transcriptional activity in HepG2 cells. Nihon Arukoru Yakubutsu Igakkai Zasshi. 2009 Jun;44(3):139-55. - Pubmed
  • Jelski W, Kozlowski M, Laudanski J, Niklinski J, Szmitkowski M: The activity of class I, II, III, and IV alcohol dehydrogenase (ADH) isoenzymes and aldehyde dehydrogenase (ALDH) in esophageal cancer. Dig Dis Sci. 2009 Apr;54(4):725-30. Epub 2008 Aug 9. - Pubmed
DTHybrid score 1.4479

Enzymes


Cytochrome P450 2E1
Name Cytochrome P450 2E1
Gene Name CYP2E1
Actions substrate,inhibitor,inducer
References
  • Flockhart DA. - Drug Interactions: Cytochrome P450 Drug Interaction Table
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
  • Lewis DF, Modi S, Dickins M: Structure-activity relationship for human cytochrome P450 substrates and inhibitors. Drug Metab Rev. 2002 Feb-May;34(1-2):69-82. - Pubmed
DTHybrid score 0.476
Cytochrome P450 1A1
Name Cytochrome P450 1A1
Gene Name CYP1A1
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3713
Cytochrome P450 1A2
Name Cytochrome P450 1A2
Gene Name CYP1A2
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.5517
Cytochrome P450 2B6
Name Cytochrome P450 2B6
Gene Name CYP2B6
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4556
Cytochrome P450 2C19
Name Cytochrome P450 2C19
Gene Name CYP2C19
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.5135
Cytochrome P450 2C9
Name Cytochrome P450 2C9
Gene Name CYP2C9
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.5654
Cytochrome P450 3A4
Name Cytochrome P450 3A4
Gene Name CYP3A4
Actions substrate,inhibitor,inducer
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.7251
Cytochrome P450 4A11
Name Cytochrome P450 4A11
Gene Name CYP4A11
Actions inducer
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.1873

Predictions


Id Partner name Gene Name Score
4119 Cytochrome P450 2D6 CYP2D6 0.3718
4924 Cytochrome P450 2C8 CYP2C8 0.2893
1588 Multidrug resistance protein 1 ABCB1 0.2606
5718 Cytochrome P450 2A6 CYP2A6 0.2294
4118 Cytochrome P450 3A5 CYP3A5 0.2292
461 Glycine receptor subunit alpha-3 GLRA3 0.1714
6107 Cytochrome P450 3A7 CYP3A7 0.1599
3411 Cytochrome P450 121 cyp121 0.1526
587 Serum albumin ALB 0.1322
62 Glycine receptor subunit beta GLRB 0.113
20 Prostaglandin G/H synthase 1 PTGS1 0.1096
2230 Catalase CAT 0.1093
3249 Catalase katA 0.1093
3625 Catalase katA 0.1093
4539 Catalase katA 0.1093
4941 Catalase katB 0.1093
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.1026
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.1013
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0986
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0986
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0982
537 ATP synthase delta chain, mitochondrial ATP5D 0.0961
6106 Cytochrome P450 2C18 CYP2C18 0.0954
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0925
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0918
705 Glutamate receptor 1 GRIA1 0.0884
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0859
1898 Cytochrome P450 1B1 CYP1B1 0.078
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.074
831 D(2) dopamine receptor DRD2 0.0737
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0731
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0728
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0693
492 Histamine H1 receptor HRH1 0.0682
3426 Glutamine synthetase glnA 0.0674
3987 Glutamine synthetase GLUL 0.0674
3811 Cytochrome P450 19A1 CYP19A1 0.0666
396 Alcohol dehydrogenase 4 ADH4 0.0641
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0631
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0628
824 Sodium-dependent serotonin transporter SLC6A4 0.0622
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0611
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0605
341 5-hydroxytryptamine 3 receptor HTR3A 0.0573
3923 Cholinesterase BCHE 0.0567
290 Prostaglandin G/H synthase 2 PTGS2 0.0565
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0562
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0545
6144 Solute carrier family 22 member 2 SLC22A2 0.0524
862 Multidrug resistance-associated protein 1 ABCC1 0.0504
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0497
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0497
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0495
3381 Alcohol dehydrogenase Not Available 0.049
4508 Alcohol dehydrogenase adhA 0.049
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0483
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0482
713 Sodium-dependent dopamine transporter SLC6A3 0.0481
1729 Solute carrier family 22 member 6 SLC22A6 0.0474
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.047
220 Sodium channel protein type 5 subunit alpha SCN5A 0.047
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0468
6145 Solute carrier family 22 member 1 SLC22A1 0.0464
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0461
921 Glutamate receptor 2 GRIA2 0.045
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0445
136 Estrogen receptor ESR1 0.0444
776 Bile salt export pump ABCB11 0.0443
502 5-hydroxytryptamine 2A receptor HTR2A 0.0442
556 Alpha-1A adrenergic receptor ADRA1A 0.0438
174 Sigma 1-type opioid receptor SIGMAR1 0.043
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0426
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0419
318 Alpha-2A adrenergic receptor ADRA2A 0.041
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.041
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0397
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0395
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0395
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0371
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0371
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.037
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.037
465 Calmodulin CALM1 0.0366
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0364
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0362
260 Cytochrome P450 51 ERG11 0.0361
761 Cytochrome P450 51 ERG11 0.0361
3163 Cytochrome P450 51 cyp51 0.0361
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0355
1758 GTPase HRas HRAS 0.0355
5469 Head decoration protein shp 0.035
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0342
590 5-hydroxytryptamine 2C receptor HTR2C 0.0342
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0338
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0336
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0329
811 Translocator protein TSPO 0.0329
23 D(1A) dopamine receptor DRD1 0.0328
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0314
3941 Amine oxidase [flavin-containing] A MAOA 0.0311
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0308
3939 Amine oxidase [flavin-containing] B MAOB 0.0302
85 Growth hormone receptor GHR 0.0291
731 HIV-1 protease HIV-1 protease 0.0291
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0288
6031 Cytochrome P450 3A43 CYP3A43 0.0288
871 Glucocorticoid receptor NR3C1 0.0287
6142 Solute carrier family 22 member 8 SLC22A8 0.0282
4311 tRNA TRDMT1 0.028
4325 tRNA trmD 0.028
4328 tRNA trmD 0.028
847 Mu-type opioid receptor OPRM1 0.0279
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0275
118 Organic cation/carnitine transporter 2 SLC22A5 0.0272
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0269
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0269
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0264
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0263
122 P2Y purinoceptor 12 P2RY12 0.026
2164 Multidrug resistance-associated protein 4 ABCC4 0.0259
36 Insulin receptor INSR 0.0258
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0258
632 Alpha-1B adrenergic receptor ADRA1B 0.0255
766 Beta-2 adrenergic receptor ADRB2 0.0255
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0253
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0253
471 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 0.025
6143 Solute carrier family 22 member 7 SLC22A7 0.0248
467 Delta-type opioid receptor OPRD1 0.0247
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0247
320 5-hydroxytryptamine 1A receptor HTR1A 0.0246
6151 Monocarboxylate transporter 10 SLC16A10 0.0245
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0244
817 DNA topoisomerase 2-alpha TOP2A 0.024
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0237
6147 Solute carrier family 22 member 3 SLC22A3 0.0234
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0234
3932 Glutathione S-transferase A2 GSTA2 0.0234
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0232
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0231
777 Tumor necrosis factor TNF 0.023
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0228
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0228
193 Beta-1 adrenergic receptor ADRB1 0.0227
2981 Phospholipase A2, membrane associated PLA2G2A 0.0223
593 Proton-coupled amino acid transporter 1 SLC36A1 0.022
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0215
885 5-hydroxytryptamine 1B receptor HTR1B 0.0211
6014 Cytochrome P450 2A13 CYP2A13 0.0209
696 Kappa-type opioid receptor OPRK1 0.0205
1757 Myeloperoxidase MPO 0.0204
2178 Metabotropic glutamate receptor 5 GRM5 0.0201
6136 Multidrug resistance-associated protein 5 ABCC5 0.0198
442 Envelope glycoprotein gp41 0.0198
4859 Envelope glycoprotein env 0.0198
789 Alpha-1D adrenergic receptor ADRA1D 0.0196
833 Organic cation/carnitine transporter 1 SLC22A4 0.0195
6220 Aryl hydrocarbon receptor AHR 0.0194
3947 Xanthine dehydrogenase/oxidase XDH 0.0193
427 Substance-P receptor TACR1 0.0193
629 Alpha-2B adrenergic receptor ADRA2B 0.0191
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0191
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0188
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0188
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0187
84 Nuclear receptor 0B1 NR0B1 0.0187
891 Dihydropteroate synthase folP 0.0183
5359 Dihydropteroate synthase folP 0.0183
7175 Dihydropteroate synthase sulI 0.0183
569 Retinal dehydrogenase 2 ALDH1A2 0.0182
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0182
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0182
16 Adenosine A1 receptor ADORA1 0.0182
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.018
613 Atrial natriuretic peptide receptor A NPR1 0.0179
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0178
638 D(3) dopamine receptor DRD3 0.0177
4096 Metabotropic glutamate receptor 3 GRM3 0.0174
1362 Metabotropic glutamate receptor 2 GRM2 0.0174
146 Androgen receptor AR 0.0173
611 Retinal dehydrogenase 1 ALDH1A1 0.0173
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0172
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0168
725 5-hydroxytryptamine 1D receptor HTR1D 0.0166
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0164
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0164
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0163
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0163
1268 Neuropeptide S receptor NPSR1 0.0163
380 Cytochrome P450 17A1 CYP17A1 0.0163
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0163
477 DNA topoisomerase 4 subunit A parC 0.0162
886 DNA topoisomerase 4 subunit A parC 0.0162
6226 DNA topoisomerase 4 subunit A parC 0.0162
6137 Multidrug resistance-associated protein 6 ABCC6 0.0161
4059 Glycine N-acyltransferase-like protein 1 GLYATL1 0.016
4056 N-arachidonyl glycine receptor GPR18 0.016
4060 Vesicular inhibitory amino acid transporter SLC32A1 0.016
4058 Glycine N-acyltransferase-like protein 2 GLYATL2 0.016
4057 Glycine N-acyltransferase GLYAT 0.016
4061 Peroxisomal sarcosine oxidase PIPOX 0.016
4055 Bile acid CoA:amino acid N-acyltransferase BAAT 0.016
1466 Glycyl-tRNA synthetase GARS 0.016
1236 Sodium- and chloride-dependent glycine transporter 1 SLC6A9 0.016
4062 Sodium- and chloride-dependent glycine transporter 2 SLC6A5 0.016
1088 5-aminolevulinate synthase, erythroid-specific, mitochondrial ALAS2 0.016
404 DNA gyrase subunit A gyrA 0.016
6224 DNA gyrase subunit A gyrA 0.016
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0158
6020 Aldehyde oxidase AOX1 0.0157
916 Metabotropic glutamate receptor 1 GRM1 0.0157
1010 Cytochrome P450 51A1 CYP51A1 0.0156
904 Glutathione S-transferase P GSTP1 0.0154
240 Gamma-aminobutyric acid type B receptor, subunit 1 GABBR1 0.0151
4604 Liver carboxylesterase 1 CES1 0.0149
592 Carbonic anhydrase 4 CA4 0.0148
1178 Adenosine A2a receptor ADORA2A 0.0146
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0142
6102 Arylamine N-acetyltransferase 2 NAT2 0.0142
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0141
4120 NADPH--cytochrome P450 reductase POR 0.0139
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0139
378 Alpha-2C adrenergic receptor ADRA2C 0.0138
6073 Potassium channel subfamily K member 9 KCNK9 0.0138
6072 Potassium channel subfamily K member 3 KCNK3 0.0138
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0138
1024 Solute carrier family 22 member 11 SLC22A11 0.0137
571 Melatonin receptor type 1A MTNR1A 0.0136
362 Melatonin receptor type 1B MTNR1B 0.0136
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0136
411 Glycine N-methyltransferase GNMT 0.0135
818 50S ribosomal protein L10 rplJ 0.0134
6148 Multidrug resistance-associated protein 7 ABCC10 0.0132
575 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial GCAT 0.013
455 5-aminolevulinate synthase, nonspecific, mitochondrial ALAS1 0.013
681 Glycine dehydrogenase [decarboxylating], mitochondrial GLDC 0.013
3191 Histidinol dehydrogenase hisD 0.013
790 DNA polymerase subunit alpha B POLA2 0.0129
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0129
6182 Cytochrome P450 2J2 CYP2J2 0.0128
6146 High affinity copper uptake protein 1 SLC31A1 0.0128
365 Dihydrofolate reductase DHFR 0.0126
2381 Dihydrofolate reductase DFR1 0.0126
2833 Dihydrofolate reductase Not Available 0.0126
2931 Dihydrofolate reductase folA 0.0126
3544 Dihydrofolate reductase folA 0.0126
3682 Dihydrofolate reductase folA 0.0126
6642 Dihydrofolate reductase folA 0.0126
6756 Dihydrofolate reductase dfrA 0.0126
70 Type-1 angiotensin II receptor AGTR1 0.0126
646 Malate dehydrogenase, cytoplasmic MDH1 0.0122
4054 Glycine cleavage system H protein, mitochondrial GCSH 0.0122
605 Fumarate reductase flavoprotein subunit frdA 0.0121
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0121
3673 Fumarate reductase flavoprotein subunit fccA 0.0121
4912 Fumarate reductase flavoprotein subunit ifcA 0.0121
6549 Fumarate reductase flavoprotein subunit frdA 0.0121
694 Matrix protein 2 M 0.0121
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0121
3884 SHMT2 protein SHMT2 0.0118
3901 SHMT2 protein SHMT2 0.0118
3885 Hypothetical protein DKFZp686P09201 DKFZp686P09201 0.0118
3879 Serine hydroxymethyltransferase 2 Not Available 0.0118
321 Serine hydroxymethyltransferase, mitochondrial SHMT2 0.0118
432 D(4) dopamine receptor DRD4 0.0118
295 Carbonic anhydrase 1 CA1 0.0118
844 Epidermal growth factor receptor EGFR 0.0117
869 Estrogen receptor beta ESR2 0.0116
48 Pyridoxal kinase PDXK 0.0116
780 Retinoic acid receptor RXR-gamma RXRG 0.0115
3116 Bacterioferritin bfr 0.0115
4906 Bacterioferritin bfr 0.0115
4965 Bacterioferritin bfr 0.0115
3709 Glycerol uptake facilitator protein glpF 0.0115
3238 Multidrug resistance protein mexA mexA 0.0115
5489 Ribonucleoside-diphosphate reductase 1 subunit beta nrdB 0.0115
3393 TGF-beta receptor type-2 TGFBR2 0.0115
3173 Enolase eno 0.0115
3336 C4-dicarboxylate transport transcriptional regulatory protein dctD dctD 0.0115
284 DNA-directed RNA polymerase beta chain rpoB 0.0115
5773 DNA-directed RNA polymerase beta chain rpoB 0.0115
207 Glutathione synthetase GSS 0.0114
5269 Glutathione synthetase gshB 0.0114
319 Opioid receptor, sigma 1 OPRS1 0.0114
114 Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 0.0114
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0114
719 Retinoic acid receptor responder protein 1 RARRES1 0.0113
2499 Tubulin beta-2C chain TUBB2C 0.0113
6141 Sodium/bile acid cotransporter SLC10A1 0.0113
770 Retinoic acid-induced protein 3 GPRC5A 0.0113
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0112
504 Mast/stem cell growth factor receptor KIT 0.0111
473 L-lactate dehydrogenase A chain LDHA 0.0111
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.011
756 Sex hormone-binding globulin SHBG 0.0109
357 Carbonic anhydrase 2 CA2 0.0109
124 Histamine H2 receptor HRH2 0.0109
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0109
94 5-hydroxytryptamine 4 receptor HTR4 0.0108
2449 Tubulin alpha-3 chain TUBA1A 0.0107
1517 Beta-3 adrenergic receptor ADRB3 0.0107
383 Glycine amidinotransferase, mitochondrial GATM 0.0107
4122 Histone deacetylase 2 HDAC2 0.0106
4116 Dihydropteroate synthetase Not Available 0.0106
1638 Solute carrier family 2, facilitated glucose transporter member 2 SLC2A2 0.0106
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0106
1656 CYP2B protein CYP2B 0.0106
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0105
714 Glutathione reductase, mitochondrial GSR 0.0104
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0104
88 Retinoic acid receptor RXR-beta RXRB 0.0103
716 5-hydroxytryptamine 7 receptor HTR7 0.0103
349 Serine--pyruvate aminotransferase AGXT 0.0102
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0102
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0102
373 Transthyretin TTR 0.0101
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0101
614 Progesterone receptor PGR 0.0101
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0101
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0101
2852 DNA mismatch repair protein mutL mutL 0.01
2207 Rhodopsin RHO 0.01
908 Glutathione S-transferase theta-1 GSTT1 0.0099
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0099
367 Serine hydroxymethyltransferase, cytosolic SHMT1 0.0099
3221 Cytochrome c4 cc4 0.0098
172 Potassium channel subfamily K member 1 KCNK1 0.0098
436 5-hydroxytryptamine 2B receptor HTR2B 0.0098
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0097
958 Insulin-like growth factor 1 receptor IGF1R 0.0097
816 Biliverdin reductase A BLVRA 0.0097
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0097
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0097
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0097
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0096
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0096
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0096
49 Endothelin B receptor EDNRB 0.0096
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0093
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0092
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0092
407 Vascular endothelial growth factor receptor 2 KDR 0.0092
6163 Copper-transporting ATPase 2 ATP7B 0.0092
6165 Copper-transporting ATPase 1 ATP7A 0.0092
6459 Glycodelin PAEP 0.0091
4209 ATP-sensitive inward rectifier potassium channel 8 KCNJ8 0.0091
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0091
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0091
578 Endothelin-1 receptor EDNRA 0.009
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.009
161 Tubulin beta chain TUBB 0.009
312 Tubulin beta chain TUB2 0.009
3810 Catechol O-methyltransferase COMT 0.009
3876 Aromatic-L-amino-acid decarboxylase DDC 0.009
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0089
6766 O-GlcNAcase BT_4395 BT_4395 0.0089
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0089
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0089
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0089
328 Sorbitol dehydrogenase SORD 0.0089
597 Dihydropteridine reductase QDPR 0.0088
823 Fibroblast growth factor receptor 2 FGFR2 0.0088
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0088
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0088
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0088
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0086
6126 Carbonic anhydrase 7 CA7 0.0086
740 Argininosuccinate synthase ASS1 0.0086
865 Argininosuccinate synthase ASS1 0.0086
2680 Argininosuccinate synthase argG 0.0086
3194 Argininosuccinate synthase argG 0.0086
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0086
228 Beta platelet-derived growth factor receptor PDGFRB 0.0086
469 Annexin A1 ANXA1 0.0086
12 Alcohol dehydrogenase class 3 ADH5 0.0085
26 Vascular endothelial growth factor receptor 3 FLT4 0.0085
183 Vascular endothelial growth factor A VEGFA 0.0085
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0085
4692 A/G-specific adenine glycosylase mutY 0.0085
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0084
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0084
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0084
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0084
33 Cystine/glutamate transporter SLC7A11 0.0083
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0083
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0083
77 L-lactate dehydrogenase B chain LDHB 0.0083
68 Cannabinoid receptor 1 CNR1 0.0083
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.0082
32 Vascular endothelial growth factor receptor 1 FLT1 0.0081
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0081
29 Tubulin beta-1 chain TUBB1 0.0081
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.008
232 Corticosteroid-binding globulin SERPINA6 0.008
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.008
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.008
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.008
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.008
666 NADP-dependent malic enzyme ME1 0.008
2802 Endoglucanase G celCCG 0.008
896 Glutathione S-transferase Mu 1 GSTM1 0.008
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.008
3937 Fatty-acid amide hydrolase FAAH 0.0079
275 Arachidonate 5-lipoxygenase ALOX5 0.0078
6316 ADP-ribosylation factor 1 ARF1 0.0078
563 Thyroid peroxidase TPO 0.0077
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0077
162 Retinoic acid receptor gamma-1 RARG 0.0077
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0077
7 Nitric oxide synthase, inducible NOS2 0.0076
3809 Estrogen-related receptor gamma ESRRG 0.0076
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0076
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0075
1192 Sulfotransferase 1A1 SULT1A1 0.0075
814 Ryanodine receptor 1 RYR1 0.0075
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0074
4228 Keratin, type II cytoskeletal 7 KRT7 0.0074
6043 Putative G-protein coupled receptor 44 GPR44 0.0073
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0073
822 Aldose reductase AKR1B1 0.0073
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0072
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0072
856 Vitamin D3 receptor VDR 0.0071
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.007
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.007
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.007
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.007
163 D(1B) dopamine receptor DRD5 0.007
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.007
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.007
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0069
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0069
153 Dopamine beta-hydroxylase DBH 0.0068
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0068
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0067
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0067
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0067
581 Cytochrome P450 2R1 CYP2R1 0.0066
4203 Histamine N-methyltransferase HNMT 0.0065
518 Peroxidase/catalase T katG 0.0065
1256 5-hydroxytryptamine 6 receptor HTR6 0.0065
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0065
1275 Estrogen sulfotransferase SULT1E1 0.0065
654 Flavin reductase BLVRB 0.0064
6085 Fatty acid-binding protein, intestinal FABP2 0.0064
1820 Beta-nerve growth factor NGF 0.0064
6138 Multidrug resistance protein 3 ABCB4 0.0063
133 Dihydropterate synthase sulI 0.0063
6432 Transporter snf 0.0063
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0062
474 Acetylcholinesterase ACHE 0.0061
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.006
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0059
4148 Serine/threonine-protein kinase mTOR MTOR 0.0059
1618 High affinity nerve growth factor receptor NTRK1 0.0059
4497 Benzyl alcohol dehydrogenase xylB 0.0059
4423 Levodione reductase lvr 0.0059
4428 Redox-sensing transcriptional repressor rex rex 0.0059
4500 L-lactate dehydrogenase 2 ldh2 0.0059
4449 ADP-ribosyltransferase Not Available 0.0059
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.0059
4435 L-aspartate dehydrogenase nadX 0.0059
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.0059
3729 Citrate synthase gltA 0.0059
4575 Citrate synthase cit 0.0059
4580 Citrate synthase gltA 0.0059
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.0059
4447 Hypothetical protein yhfP yhfP 0.0059
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.0059
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.0059
4487 Transcriptional regulator nadR nadR 0.0059
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.0059
4414 Dehydrogenase TT_P0035 0.0059
2350 3-isopropylmalate dehydrogenase leuB 0.0059
3092 3-isopropylmalate dehydrogenase leuB 0.0059
4418 AGR_L_3209p AGR_L_3209 0.0059
4507 Alanine dehydrogenase ald 0.0059
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.0059
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.0059
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.0059
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.0059
4502 Formate dehydrogenase Not Available 0.0059
4455 Glycerol dehydrogenase gldA 0.0059
4451 Vip2Ac vip2Ac 0.0059
4472 Glucose 1-dehydrogenase Not Available 0.0059
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.0059
4443 Quinate/shikimate dehydrogenase ydiB 0.0059
4467 Alpha-glucosidase, putative TM_0752 0.0059
4471 CDP-D-glucose-4,6-dehydratase ascB 0.0059
2159 Quinone oxidoreductase CRYZ 0.0058
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0058
634 Squalene monooxygenase SQLE 0.0057
7196 Squalene monooxygenase ERG1 0.0057
976 Platelet glycoprotein IX GP9 0.0057
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0057
106 Cannabinoid receptor 2 CNR2 0.0057
528 5-hydroxytryptamine 1E receptor HTR1E 0.0057
1629 Transcription factor AP-1 JUN 0.0056
1714 Mitogen-activated protein kinase 3 MAPK3 0.0056
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0056
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0056
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0056
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0056
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0056
511 5-hydroxytryptamine 1F receptor HTR1F 0.0055
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0054
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0054
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0054
627 11-cis retinol dehydrogenase RDH5 0.0054
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0054
273 Apoptosis regulator Bcl-2 BCL2 0.0053
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0053
390 Adenosine A3 receptor ADORA3 0.0053
1992 Vitamin D-binding protein GC 0.0053
5998 Toll-like receptor 8 TLR8 0.0053
6339 Ig kappa chain V-II region RPMI 6410 Not Available 0.0052
565 Extracellular calcium-sensing receptor CASR 0.0052
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0052
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0052
712 Tubulin alpha chain TUB1 0.0052
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0052
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0052
3090 Chitosanase csn 0.0052
4149 Nuclear factor NF-kappa-B p100 subunit NFKB2 0.0052
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0052
3823 Cytokine receptor common gamma chain IL2RG 0.0051
54 Prothrombin F2 0.0051
952 Dipeptidyl peptidase 4 DPP4 0.0051
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.005
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.005
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.005
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.005
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.005
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.005
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.005
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.005
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.005
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.005
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.005
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.005
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.005
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.005
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.005
602 Acyl carrier protein, mitochondrial NDUFAB1 0.005
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.005
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.005
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.005
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.005
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.005
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.005
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.005
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.005
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.005
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.005
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.005
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.005
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.005
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.005
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.005
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.005
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.005
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.005
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.005
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.005
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.005
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.005
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.005
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.005
729 GDP-L-fucose synthetase TSTA3 0.005
3463 GDP-L-fucose synthetase fcl 0.005
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.005
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.005
167 L-lactate dehydrogenase C chain LDHC 0.005
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.005
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.005
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.005
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.005
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.005
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.005
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.005
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.005
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.005
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.005
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.005
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.005
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.005
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.005
107 C-4 methylsterol oxidase SC4MOL 0.005
206 3-keto-steroid reductase HSD17B7 0.005
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.005
662 Fatty aldehyde dehydrogenase ALDH3A2 0.005
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.005
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.005
711 UDP-glucose 6-dehydrogenase UGDH 0.005
3672 UDP-glucose 6-dehydrogenase hasB 0.005
644 Heme oxygenase 2 HMOX2 0.005
4982 Heme oxygenase 2 pbsA2 0.005
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.005
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.005
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.005
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.005
3726 D-3-phosphoglycerate dehydrogenase serA 0.005
4291 D-3-phosphoglycerate dehydrogenase serA 0.005
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.005
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.005
34 7-dehydrocholesterol reductase DHCR7 0.005
643 Peroxisomal bifunctional enzyme EHHADH 0.005
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.005
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.005
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0049
1680 Solute carrier family 2, facilitated glucose transporter member 1 SLC2A1 0.0049
239 Coagulation factor X F10 0.0049
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0049
5934 Cytochrome P450 26A1 CYP26A1 0.0048
1374 Natriuretic peptides B NPPB 0.0048
1827 Gap junction alpha-1 protein GJA1 0.0048
1908 Vascular cell adhesion protein 1 VCAM1 0.0048
4427 TDP-glucose-4,6-dehydratase desIV 0.0048
3177 dTDP-glucose 4,6-dehydratase rfbB 0.0048
4499 dTDP-glucose 4,6-dehydratase rmlB 0.0048
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.0048
4486 Phenol 2-hydroxylase component B pheA2 0.0048
4439 Ferredoxin reductase bphA4 0.0048
4477 Dihydrolipoyl dehydrogenase lpdV 0.0048
5077 Dihydrolipoyl dehydrogenase Not Available 0.0048
5117 Dihydrolipoyl dehydrogenase lpd 0.0048
2967 CDP-paratose 2-epimerase rfbE 0.0048
4482 UDP-galactose 4-epimerase galE 0.0048
4503 NADPH-flavin oxidoreductase frp 0.0048
2507 Diphtheria toxin Not Available 0.0048
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0048
4509 Acetoin(diacetyl) reductase budC 0.0047
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.0047
3615 Dihydrodipicolinate reductase dapB 0.0047
3618 Dihydrodipicolinate reductase dapB 0.0047
4462 Dihydrodipicolinate reductase dapB 0.0047
2591 Urocanate hydratase hutU 0.0047
2393 Maltose-6'-phosphate glucosidase glvA 0.0047
2538 6-phospho-beta-glucosidase bglT bglT 0.0047
3081 3-dehydroquinate synthase aroB 0.0047
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0047
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.0047
126 D-lactate dehydrogenase dld 0.0047
3545 D-lactate dehydrogenase Not Available 0.0047
4510 D-lactate dehydrogenase ldhA 0.0047
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0047
4450 Iota toxin component Ia Not Available 0.0047
2424 L-lactate dehydrogenase ldh 0.0047
2641 L-lactate dehydrogenase Not Available 0.0047
4437 L-lactate dehydrogenase ldh 0.0047
4442 L-lactate dehydrogenase ldh 0.0047
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.0047
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.0047
3401 D-2-hydroxyisocaproate dehydrogenase Not Available 0.0047
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0047
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0047
4496 C-terminal-binding protein 1 CTBP1 0.0047
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.0047
2018 Deoxyhypusine synthase DHPS 0.0047
2336 2,3-diketo-L-gulonate reductase dlgD 0.0047
4498 Ornithine cyclodeaminase PP3533 0.0047
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0047
857 Malate dehydrogenase, mitochondrial MDH2 0.0047
738 Monocarboxylate transporter 1 SLC16A1 0.0047
723 Cytosolic phospholipase A2 PLA2G4A 0.0047
1483 Membrane copper amine oxidase AOC3 0.0046
1050 Bile salt sulfotransferase SULT2A1 0.0046
1253 Interferon gamma IFNG 0.0046
2236 Casein kinase II subunit alpha CSNK2A1 0.0046
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0046
173 Toll-like receptor 7 TLR7 0.0046
4237 50S ribosomal protein L22 rplV 0.0046
737 Mineralocorticoid receptor NR3C2 0.0045
3957 Adenosine deaminase ADA 0.0045
992 Protein tyrosine kinase 2 beta PTK2B 0.0045
527 Prostacyclin receptor PTGIR 0.0045
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0045
724 Interleukin-2 receptor alpha chain IL2RA 0.0045
717 Interleukin-2 receptor subunit beta IL2RB 0.0045
2683 Mono-ADP-ribosyltransferase C3 C3 0.0045
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0045
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0044
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.0044
6026 Alcohol dehydrogenase 6 ADH6 0.0044
130 Prostacyclin synthase PTGIS 0.0044
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0044
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0044
6044 Serum paraoxonase/lactonase 3 PON3 0.0044
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0044
3830 Calreticulin CALR 0.0043
4504 WbpP Not Available 0.0043
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0043
4103 Proteasome subunit beta type 2 PSMB2 0.0043
4102 Proteasome subunit beta type 5 PSMB5 0.0043
4101 Proteasome subunit beta type 1 PSMB1 0.0043
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.0043
3367 GDP-mannose 6-dehydrogenase algD 0.0043
2391 Ferrochelatase hemH 0.0043
6502 Ferrochelatase DKFZp686P18130 0.0043
1591 Ferrochelatase, mitochondrial FECH 0.0043
2539 Tubulin alpha-1 chain TUBA4A 0.0043
4440 NADH peroxidase npr 0.0043
4318 Siroheme synthase cysG 0.0043
3917 Methylenetetrahydrofolate reductase MTHFR 0.0043
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0042
4343 Alpha-glucosidase aglA 0.0042
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.0042
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0042
4476 Mannitol dehydrogenase mtlD 0.0042
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0042
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0042
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0042
63 Malate dehydrogenase mdh 0.0042
2329 Malate dehydrogenase mdh 0.0042
3445 Malate dehydrogenase mdh 0.0042
4420 Malate dehydrogenase mdh 0.0042
4438 Malate dehydrogenase mdh 0.0042
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0042
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0042
5322 Oxidoreductase ydhF ydhF 0.0042
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0042
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0042
5332 MtdA bifunctional protein mtdA 0.0042
5330 General stress protein 69 yhdN 0.0042
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0042
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0042
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0042
3778 NAD(P) transhydrogenase subunit beta pntB 0.0042
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0042
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0042
4403 Protein iolS iolS 0.0042
626 Cysteine dioxygenase type 1 CDO1 0.0042
936 Ephrin type-A receptor 2 EPHA2 0.0042
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0042
13 Aminomethyltransferase, mitochondrial AMT 0.0042
1648 Elastin ELN 0.0041
1176 Mitogen-activated protein kinase 1 MAPK1 0.0041
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0041
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0041
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0041
459 Retinoic acid receptor RXR-alpha RXRA 0.0041
6034 Hydroxyindole O-methyltransferase ASMT 0.0041
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0041
6035 Nuclear receptor ROR-beta RORB 0.0041
3997 Cytochrome P450 24A1, mitochondrial CYP24A1 0.0041
6036 Eosinophil peroxidase EPX 0.0041
268 Adenosine A2b receptor ADORA2B 0.0041
448 Vitamin K-dependent gamma-carboxylase GGCX 0.004
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.004
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.004
2826 Glucose--fructose oxidoreductase gfo 0.004
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.004
751 Potassium channel subfamily K member 6 KCNK6 0.004
2434 NH(3)-dependent NAD(+) synthetase nadE 0.004
2910 NH(3)-dependent NAD(+) synthetase nadE 0.004
3217 NH(3)-dependent NAD(+) synthetase nadE 0.004
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.004
3070 Adenosylhomocysteinase AHCY 0.004
4424 Adenosylhomocysteinase PFE1050w 0.004
6278 Adenosylhomocysteinase ahcY 0.004
327 Glutathione reductase gor 0.004
5110 Glutathione reductase GR2 0.004
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.004
1541 Metalloproteinase mmp20 0.0039
3808 Dihydropteroate synthase 2 folP2 0.0039
3601 Dihydropteroate synthase 1 folP1 0.0039
3807 Dihydropteroate synthase 1 folP1 0.0039
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0039
810 Heme oxygenase 1 HMOX1 0.0039
3391 Heme oxygenase 1 pbsA1 0.0039
4146 Phosphatidylinositol 3-kinase regulatory subunit gamma PIK3R3 0.0039
4145 Phosphatidylinositol 3-kinase regulatory subunit beta PIK3R2 0.0039
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0039
1129 C-C chemokine receptor type 5 CCR5 0.0039
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.0039
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0038
4192 DNA topoisomerase 2-beta TOP2B 0.0038
24 Thymidylate synthase TMP1 0.0038
359 Thymidylate synthase TYMS 0.0038
2626 Thymidylate synthase thyA 0.0038
2729 Thymidylate synthase thyA 0.0038
5352 Thymidylate synthase THYA 0.0038
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.0037
400 Coagulation factor IX F9 0.0037
5461 Coagulation factor IX F9 0.0037
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.0037
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.0037
6493 Cytochrome c oxidase subunit 6C COX6C 0.0037
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.0037
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.0037
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.0037
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.0037
371 Cytochrome c oxidase subunit 1 MT-CO1 0.0037
6558 Cytochrome c oxidase subunit 1 ctaD 0.0037
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.0037
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0037
6559 Cytochrome c oxidase subunit 2 ctaC 0.0037
6669 Cytochrome c oxidase subunit 2 ctaC 0.0037
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.0037
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0037
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0037
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0037
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0037
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0037
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0037
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.0037
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0037
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0037
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0037
5073 Ferredoxin--NADP reductase petH 0.0037
5076 Ferredoxin--NADP reductase fpr 0.0037
5119 Ferredoxin--NADP reductase petH 0.0037
5121 Ferredoxin--NADP reductase fpr 0.0037
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0037
267 Plasminogen activator inhibitor 1 SERPINE1 0.0036
279 Tyrosinase TYR 0.0036
2112 Toll-like receptor 9 TLR9 0.0036
3446 NADP-dependent alcohol dehydrogenase adh 0.0036
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0036
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0036
4582 Putative pteridine reductase 2 ptr2 0.0036
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0036
989 L-xylulose reductase DCXR 0.0036
164 Histamine H4 receptor HRH4 0.0036
2636 Shikimate dehydrogenase aroE 0.0036
3515 Shikimate dehydrogenase aroE 0.0036
5328 Prostaglandin F synthase Tb11.02.2310 0.0036
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0036
4491 DNA ligase, NAD-dependent ligA 0.0036
2286 Isocitrate dehydrogenase [NADP] icd 0.0036
2302 Isocitrate dehydrogenase [NADP] icd 0.0036
2771 Isocitrate dehydrogenase [NADP] icd 0.0036
633 Penicillin-binding proteins 1A/1B pbpA 0.0036
6131 Carbonic anhydrase 14 CA14 0.0036
3404 Exotoxin A eta 0.0036
735 Alanine aminotransferase 1 GPT 0.0036
3904 Alanine aminotransferase 2 GPT2 0.0036
2762 UDP-glucose 4-epimerase GALE 0.0035
3461 UDP-glucose 4-epimerase galE 0.0035
65 Matrix metalloproteinase-9 Not Available 0.0035
765 Indoleamine 2,3-dioxygenase IDO1 0.0035
185 Vasopressin V1a receptor AVPR1A 0.0035
117 Sterol O-acyltransferase 1 SOAT1 0.0035
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0035
939 50S ribosomal protein L3 rplC 0.0035
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0034
3587 Gastrotropin FABP6 0.0034
2540 Choloylglycine hydrolase cbh 0.0034
322 Vasopressin V2 receptor AVPR2 0.0034
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0034
604 Vitamin K-dependent protein Z PROZ 0.0034
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0034
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0034
558 Solute carrier family 12 member 1 SLC12A1 0.0033
6122 Carbonic anhydrase 3 CA3 0.0033
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0033
1281 Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 0.0033
6297 Prostaglandin reductase 1 PTGR1 0.0033
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.0033
4531 Putative ketoacyl reductase actIII 0.0033
3062 Aspartate-semialdehyde dehydrogenase asd 0.0033
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0033
6221 Steroid hormone receptor ERR1 ESRRA 0.0033
6501 Fatty acid-binding protein, liver FABP1 0.0032
1630 Integrin beta-2 ITGB2 0.0032
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0032
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0032
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0032
2675 Pteridine reductase 1 PTR1 0.0032
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0032
140 30S ribosomal protein S9 rpsI 0.0031
6719 30S ribosomal protein S9 rpsI 0.0031
6725 30S ribosomal protein S9 rpsI 0.0031
1124 Sepiapterin reductase SPR 0.0031
422 Vitamin K-dependent protein C PROC 0.0031
1245 Vitamin K-dependent protein S PROS1 0.0031
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0031
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0031
1227 Cytochrome b MT-CYB 0.0031
6386 Cytochrome b petB 0.0031
6937 Cytochrome b MT-CYB 0.0031
674 Dihydroorotate dehydrogenase homolog, mitochondrial PFF0160c 0.0031
5300 Antigen peptide transporter 1 TAP1 0.0031
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0031
2578 Tubulin beta-3 chain TUBB3 0.003
2285 Streptogramin A acetyltransferase vatD 0.003
543 Penicillin-binding protein 1B mrcB 0.003
6186 Penicillin-binding protein 1B ponB 0.003
6822 Penicillin-binding protein 1b pbp1b 0.003
6844 Penicillin-binding protein 1b pbp1b 0.003
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.003
165 FL cytokine receptor FLT3 0.003
6174 50S ribosomal protein L32 rpmF 0.003
76 Nitric-oxide synthase, brain NOS1 0.003
159 Penicillin-binding protein 2B penA 0.0029
6121 Penicillin-binding protein 2B penA 0.0029
1196 Complement decay-accelerating factor CD55 0.0029
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0029
4238 50S ribosomal protein L4 rplD 0.0029
5578 50S ribosomal protein L4 rplD 0.0029
6173 50S ribosomal protein L4 rplD 0.0029
6219 50S ribosomal protein L4 rplD 0.0029
2298 Cytochrome P450-cam camC 0.0029
3913 Glutamic acid decarboxylase GAD65 0.0029
1360 Sphingomyelin phosphodiesterase SMPD1 0.0029
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0029
1569 G1/S-specific cyclin-D1 CCND1 0.0029
512 DNA-directed RNA polymerase alpha chain rpoA 0.0029
5772 DNA-directed RNA polymerase alpha chain rpoA 0.0029
2290 ADP-ribosyl cyclase 2 BST1 0.0028
330 Spermidine synthase SRM 0.0028
3038 Spermidine synthase speE 0.0028
131 Synaptic vesicular amine transporter SLC18A2 0.0028
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0028
1063 Signal transducer and activator of transcription 5B STAT5B 0.0028
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0028
1200 AMBP protein AMBP 0.0028
3866 Serum amyloid A protein SAA1 0.0028
1932 Apolipoprotein E APOE 0.0028
5787 Angiopoietin-1 receptor TEK 0.0027
1144 Hepatocyte growth factor receptor MET 0.0027
4173 Tyrosine-protein kinase JAK2 JAK2 0.0027
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0027
3849 Insulin-like growth factor-binding protein 7 IGFBP7 0.0027
2009 Protein NOV homolog NOV 0.0027
3847 Neuroendocrine convertase 2 PCSK2 0.0027
1949 Carboxypeptidase E CPE 0.0027
3850 Synaptotagmin-like protein 4 SYTL4 0.0027
3848 Neuroendocrine convertase 1 PCSK1 0.0027
3846 Retinoblastoma-associated protein RB1 0.0027
6500 Phospholipase A2 PLA2G1B 0.0026
1039 Histone deacetylase 9 HDAC9 0.0026
358 Cystathionine beta-synthase CBS 0.0026
291 Nitric-oxide synthase, endothelial NOS3 0.0026
2808 Chloramphenicol acetyltransferase 3 cat3 0.0026
798 Osteocalcin BGLAP 0.0025
5880 Thrombopoietin receptor MPL 0.0025
6149 Solute carrier family 22 member 10 SLC22A10 0.0025
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0025
768 FK506-binding protein 1A FKBP1A 0.0025
5798 Mitogen-activated protein kinase 11 MAPK11 0.0025
3007 Carbonic anhydrase 12 CA12 0.0025
4205 Carbonic anhydrase 9 CA9 0.0025
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0024
334 S-adenosylmethionine synthetase isoform type-2 MAT2A 0.0024
544 Potassium voltage-gated channel subfamily E member 1 KCNE1 0.0024
6039 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A PDE11A 0.0024
3639 Thymidine phosphorylase deoA 0.0024
3936 Thymidine phosphorylase TYMP 0.0024
6070 Nischarin NISCH 0.0024
5852 Type-2 angiotensin II receptor AGTR2 0.0024
208 DNA-directed RNA polymerase beta' chain rpoC 0.0023
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0023
642 3-oxo-5-alpha-steroid 4-dehydrogenase 2 SRD5A2 0.0023
2417 Chloramphenicol acetyltransferase cat 0.0023
3278 Chloramphenicol acetyltransferase cat 0.0023
550 Amiloride-sensitive sodium channel subunit delta SCNN1D 0.0023
27 Amiloride-sensitive sodium channel subunit beta SCNN1B 0.0023
552 Amiloride-sensitive sodium channel subunit gamma SCNN1G 0.0023
213 Amiloride-sensitive sodium channel subunit alpha SCNN1A 0.0023
1830 5'-nucleotidase NT5E 0.0023
2810 Dr hemagglutinin structural subunit draA 0.0023
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0023
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0023
1353 DNA topoisomerase 1 TOP1 0.0023
3552 DNA topoisomerase 1 topA 0.0023
369 Coagulation factor VII F7 0.0023
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0023
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0023
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0023
1262 Corticotropin-lipotropin POMC 0.0023
484 Tyrosine-protein kinase ABL2 ABL2 0.0022
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0022
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0022
113 S-adenosylmethionine decarboxylase proenzyme AMD1 0.0022
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0022
2155 Insulin-degrading enzyme IDE 0.0022
2232 Interleukin-5 IL5 0.0022
997 Protein kinase C beta type PRKCB 0.0021
298 Renin REN 0.0021
1593 Mucin-2 MUC2 0.0021
6506 Stathmin-4 STMN4 0.0021
2091 Endoplasmin HSP90B1 0.0021
1244 Low-density lipoprotein receptor-related protein 2 LRP2 0.0021
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0021
1852 Microtubule-associated protein 2 MAP2 0.0021
828 Phenylalanine-4-hydroxylase PAH 0.0021
3109 Phenylalanine-4-hydroxylase phhA 0.0021
3611 Cytidine deaminase cdd 0.002
3707 Cytidine deaminase cdd 0.002
4211 Cytidine deaminase CDA 0.002
1970 Protein kinase C alpha type PRKCA 0.002
1864 RET proto-oncogene RET 0.002
6103 Arylamine N-acetyltransferase 1 NAT1 0.002
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.002
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.002
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.002
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.002
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.002
2408 Tyrosine-protein kinase SYK SYK 0.0019
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0019
718 Folate receptor gamma FOLR3 0.0019
299 Folate receptor beta FOLR2 0.0019
804 Mitochondrial folate transporter/carrier SLC25A32 0.0019
233 Potassium channel subfamily K member 2 KCNK2 0.0019
4217 Telomerase reverse transcriptase TERT 0.0019
1968 ATP-sensitive inward rectifier potassium channel 12 KCNJ12 0.0018
683 Potassium transporter GK0582 0.0018
1123 Eosinophil cationic protein RNASE3 0.0018
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0017
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0017
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0017
4773 Deoxycytidine kinase DCK 0.0017
293 Gamma-glutamyl hydrolase GGH 0.0017
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0017
1243 Cathepsin D CTSD 0.0016
3233 Bile acid receptor NR1H4 0.0015
2853 14 kDa fatty acid-binding protein Not Available 0.0015
3856 Fibroblast growth factor receptor 3 FGFR3 0.0015
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0015
922 Glutamate receptor 4 GRIA4 0.0015
924 Glutamate receptor, ionotropic kainate 3 GRIK3 0.0015
919 Glutamate receptor, ionotropic kainate 4 GRIK4 0.0015
4024 Mitochondrial glutamate carrier 2 SLC25A18 0.0015
920 Glutamate receptor, ionotropic kainate 5 GRIK5 0.0015
4025 Mitochondrial glutamate carrier 1 SLC25A22 0.0015
4022 Glutamate--ammonia ligase domain-containing protein 1 LGSN 0.0015
4018 Glutamate receptor delta-2 subunit GRID2 0.0015
4027 Glutamate receptor delta-1 subunit GRID1 0.0015
1912 Excitatory amino acid transporter 1 SLC1A3 0.0015
4019 Excitatory amino acid transporter 4 SLC1A6 0.0015
4016 Excitatory amino acid transporter 5 SLC1A7 0.0015
4026 Aspartyl aminopeptidase DNPEP 0.0015
915 Delta 1-pyrroline-5-carboxylate synthetase ALDH18A1 0.0015
4021 Probable glutamyl-tRNA synthetase, mitochondrial EARS2 0.0015
4023 N-acetylglutamate synthase, mitochondrial NAGS 0.0015
1047 Excitatory amino acid transporter 2 SLC1A2 0.0015
664 Glutamate decarboxylase 2 GAD2 0.0015
3890 Glutamate decarboxylase 2 GAD2 0.0015
4017 5-oxoprolinase OPLAH 0.0015
927 Metabotropic glutamate receptor 8 GRM8 0.0015
925 Metabotropic glutamate receptor 4 GRM4 0.0015
926 Metabotropic glutamate receptor 7 GRM7 0.0015
4020 Glutamyl aminopeptidase ENPEP 0.0015
3844 HLA class II histocompatibility antigen, DQ(6) alpha chain HLA-DQA2 0.0015
1650 Heme carrier protein 1 SLC46A1 0.0015
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0015
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0015
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0015
572 Integrin alpha-L ITGAL 0.0015
2320 Thymidine kinase, cytosolic TK1 0.0014
1341 Histamine H3 receptor HRH3 0.0014
4226 Uridine phosphorylase 2 UPP2 0.0014
6167 Organic solute transporter subunit beta OSTB 0.0014
6166 Organic solute transporter subunit alpha OSTA 0.0014
6859 Protein S100-A4 S100A4 0.0014
2300 Lysozyme E 0.0014
3633 Lysozyme R 0.0014
5597 Lysozyme 17 0.0014
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0014
625 Glutamate carboxypeptidase 2 FOLH1 0.0013
561 Retinol-binding protein II, cellular RBP2 0.0013
35 Dehydrogenase/reductase SDR family member 4 DHRS4 0.0013
4073 Retinol dehydrogenase 11 RDH11 0.0013
4074 Retinol dehydrogenase 14 RDH14 0.0013
1097 Lecithin retinol acyltransferase LRAT 0.0013
589 Retinoid-binding protein 7 RBP7 0.0013
753 Retinol-binding protein III, cellular RBP5 0.0013
4071 Short-chain dehydrogenase/reductase 3 DHRS3 0.0013
4075 Photoreceptor outer segment all-trans retinol dehydrogenase RDH8 0.0013
863 Cellular retinaldehyde-binding protein RLBP1 0.0013
800 Retinol dehydrogenase 12 RDH12 0.0013
282 Interphotoreceptor retinoid-binding protein RBP3 0.0013
651 Retinol dehydrogenase 13 RDH13 0.0013
4072 All-trans-retinol 13,14-reductase RETSAT 0.0013
6218 Pannexin-1 PANX1 0.0013
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0013
801 Kynurenine/alpha-aminoadipate aminotransferase mitochondrial AADAT 0.0013
665 Phosphoserine aminotransferase PSAT1 0.0013
4652 Phosphoserine aminotransferase serC 0.0013
3895 Kynurenine--oxoglutarate transaminase 3 CCBL2 0.0013
420 Glutamate decarboxylase 1 GAD1 0.0013
3900 Glutamate decarboxylase 1 GAD1 0.0013
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0013
4225 Uridine phosphorylase 1 UPP1 0.0013
3984 Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial PET112L 0.0013
917 Glutaminase kidney isoform, mitochondrial GLS 0.0013
3991 Glutamine-dependent NAD(+) synthetase NADSYN1 0.0013
5 Glutaminase liver isoform, mitochondrial GLS2 0.0013
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0013
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0013
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0013
5261 Phosphoribosylformylglycinamidine synthase purL 0.0013
668 Glutamate--cysteine ligase regulatory subunit GCLM 0.0013
5626 Nucleoside diphosphate kinase B NME2 0.0013
6116 Gastric triacylglycerol lipase LIPF 0.0012
2021 Thrombomodulin THBD 0.0012
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0012
2107 Microtubule-associated protein 1A MAP1A 0.0012
338 DNA polymerase UL30 0.0012
379 DNA polymerase UL54 0.0012
697 DNA polymerase ORF28 0.0012
2482 DNA polymerase 43 0.0012
4104 DNA polymerase BALF5 0.0012
413 Amidophosphoribosyltransferase PPAT 0.0012
2515 Amidophosphoribosyltransferase purF 0.0012
3714 Amidophosphoribosyltransferase purF 0.0012
5924 Microtubule-associated protein 4 MAP4 0.0012
5923 Microtubule-associated protein tau MAPT 0.0012
923 Glutamate receptor 3 GRIA3 0.0012
1295 Fatty acid synthase FASN 0.0012
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0012
186 Glutamate--cysteine ligase catalytic subunit GCLC 0.0012
3877 Growth-inhibiting protein 18 GIG18 0.0012
331 Retinol-binding protein I, cellular RBP1 0.0012
763 Tyrosine aminotransferase TAT 0.0012
5493 Tyrosine aminotransferase Not Available 0.0012
1671 Excitatory amino acid transporter 3 SLC1A1 0.0012
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0011
914 Formimidoyltransferase-cyclodeaminase FTCD 0.0011
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0011
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0011
426 Aspartate aminotransferase, mitochondrial GOT2 0.0011
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0011
754 Pancreatic triacylglycerol lipase PNLIP 0.0011
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0011
2183 Fatty acid-binding protein, adipocyte FABP4 0.0011
210 Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase EPRS 0.0011
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0011
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.001
6033 High affinity interleukin-8 receptor A CXCR1 0.001
1810 Protein S100-A1 S100A1 0.001
6097 Protein S100-A2 S100A2 0.001
4948 Cytochrome c-553 Not Available 0.001
4923 Cytochrome c3 DvMF_2499 0.001
4945 Cytochrome c3 Not Available 0.001
4949 Cytochrome c3 DVU_3171 0.001
4968 Cytochrome c3 cytc3 0.001
4997 Cytochrome c3 SO_2727 0.001
5219 Cytochrome c3 cyd 0.001
4902 Nine-heme cytochrome c Ddes_2038 0.001
3189 High-molecular-weight cytochrome c hmcA 0.001
493 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 0.001
5294 Nucleoside diphosphate kinase A NME1 0.001
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.001
574 Branched-chain-amino-acid aminotransferase, cytosolic BCAT1 0.001
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.001
345 Plasma retinol-binding protein RBP4 0.001
4041 Microsomal glutathione S-transferase 2 MGST2 0.001
6824 Tyrosine-protein kinase Lyn LYN 0.001
2268 Cholesterol oxidase choB 0.0009
2822 Cholesterol oxidase choA 0.0009
6048 Troponin C, skeletal muscle TNNC2 0.0009
6168 Solute carrier family 22 member 16 SLC22A16 0.0009
229 Retinoic acid receptor beta RARB 0.0009
6105 3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 0.0009
3086 Plasmepsin-2 Not Available 0.0009
730 Retinoic acid receptor alpha RARA 0.0009
1048 Protein S100-A13 S100A13 0.0009
2226 Protein S100-A12 S100A12 0.0009
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0009
1770 Phospholipase C PLCL1 0.0009
2841 Phospholipase C plc 0.0009
6042 Prostaglandin reductase 2 PTGR2 0.0009
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0009
2283 Steroid Delta-isomerase ksi 0.0009
2920 Steroid Delta-isomerase ksi 0.0009
4386 Hemoglobin-like protein HbN glbN 0.0009
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0009
2132 Protein S100-B S100B 0.0009
1792 Tissue-type plasminogen activator PLAT 0.0008
22 30S ribosomal protein S4 rpsD 0.0008
6714 30S ribosomal protein S4 rpsD 0.0008
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0008
489 Monocarboxylate transporter 2 SLC16A7 0.0008
760 Fibroblast growth factor 1 FGF1 0.0008
1867 Major prion protein PRNP 0.0008
4031 Glutathione S-transferase A1 GSTA1 0.0008
1649 Small inducible cytokine A2 CCL2 0.0008
1025 Aquaporin-1 AQP1 0.0008
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0007
6228 Nuclear receptor coactivator 1 NCOA1 0.0007
6207 30S ribosomal protein S14 rpsN 0.0007
6209 30S ribosomal protein S19 rpsS 0.0007
6712 30S ribosomal protein S19 rpsS 0.0007
6726 30S ribosomal protein S19 rpsS 0.0007
6134 Sodium channel subunit beta-3 SCN3B 0.0007
6133 Sodium channel subunit beta-2 SCN2B 0.0007
6135 Sodium channel subunit beta-4 SCN4B 0.0007
6241 Nuclear receptor coactivator 2 NCOA2 0.0007
6132 Sodium channel subunit beta-1 SCN1B 0.0007
6129 Carbonic anhydrase-related protein 11 CA11 0.0007
6127 Carbonic anhydrase-related protein CA8 0.0007
6128 Carbonic anhydrase-related protein 10 CA10 0.0007
645 Penicillin-binding protein 1A mrcA 0.0007
5805 Penicillin-binding protein 1A ponA 0.0007
6185 Penicillin-binding protein 1A mrcA 0.0007
6799 Penicillin-binding protein 1A pbpA 0.0007
1313 Lactoylglutathione lyase GLO1 0.0007
226 Gonadotropin-releasing hormone receptor GNRHR 0.0007
1507 Cytochrome c CYCS 0.0007
125 DNA polymerase beta POLB 0.0007
2599 Tyrosine-protein kinase HCK HCK 0.0007
144 Hemoglobin subunit alpha HBA1 0.0006
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0006
6130 Carbonic anhydrase 13 CA13 0.0006
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0006
4954 Soluble cytochrome b558 Not Available 0.0006
4925 Cytochrome c-type protein SHP shp 0.0006
4916 Cyanoglobin glbN 0.0006
4915 Cytochrome c-550 psbV 0.0006
4959 Cytochrome c-550 psbV 0.0006
5216 Cytochrome c-550 psbV 0.0006
4947 Bacterial hemoglobin vhb 0.0006
4934 Cytochrome c-551 nirM 0.0006
5218 Cytochrome c-551 nirM 0.0006
4994 Hemoglobin-like protein HbO glbO 0.0006
4984 Neuroglobin NGB 0.0006
4943 Cytochrome c6 petJ 0.0006
4975 Cytochrome c-556 RPA3973 0.0006
4905 Cytochrome c2 Not Available 0.0006
4939 Cytochrome c2 cycA 0.0006
4964 Cytochrome c2 cycA 0.0006
4979 Cytochrome c2 cycA 0.0006
6673 Cytochrome c2 cycA 0.0006
4910 Cytoglobin CYGB 0.0006
4936 Cytochrome c2 iso-2 Not Available 0.0006
4998 Hemoglobin-like protein yjbI yjbI 0.0006
4981 Iron-starvation protein PigA pigA 0.0006
5000 HemO hemO 0.0006
4907 Cytochrome c-L moxG 0.0006
6865 Cytochrome c-L moxG 0.0006
4909 CooA protein cooA 0.0006
4935 Cytochrome c-554 cycA1 0.0006
4942 Diheme cytochrome c napB napB 0.0006
4971 Nonaheme cytochrome c hmcA 0.0006
4904 Cytochrome c family protein GSU1996 0.0006
4961 Hemophore HasA hasA 0.0006
4976 Apocytochrome f petA 0.0006
6407 Apocytochrome f petA 0.0006
4764 Cytochrome P450 165C4 CYP165C4 0.0006
4972 P450cin cinA 0.0006
4931 Cytochrome P450 167A1 CYP167A1 0.0006
4960 Putative cytochrome P450-family protein SCO7417 0.0006
4903 Methyl-accepting chemotaxis protein Tar4 0.0006
4926 Heme-based aerotactic transducer hemAT hemAT 0.0006
4999 Cytochrome P450 165B3 CYP165B3 0.0006
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0006
4989 Cytochrome c551 peroxidase ccp 0.0006
5222 Cytochrome c551 peroxidase ccpA 0.0006
4937 Cytochrome oxidase subunit II rcoxA 0.0006
4922 Cytochrome c, putative SO_4144 0.0006
4993 Hydroxylamine oxidoreductase hao1 0.0006
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0006
3093 Catalase HPII katE 0.0006
4952 Catalase/peroxidase katA 0.0006
1291 cAMP response element-binding protein CREB1 0.0006
1525 Heparin-binding growth factor 2 FGF2 0.0006
5221 Cytochrome c3, 13 kDa Not Available 0.0006
3152 Cytochrome c'' cycA 0.0006
5220 Split-Soret cytochrome c Ddes_2150 0.0006
3700 Cytochrome c-552 precursor nrfA 0.0006
4210 Toll-like receptor 4 TLR4 0.0005
1760 Aminopeptidase N ANPEP 0.0005
6843 Aminopeptidase N pepN 0.0005
244 Angiotensin-converting enzyme ACE 0.0005
6211 Tubulin epsilon chain TUBE1 0.0005
6212 Tubulin gamma-1 chain TUBG1 0.0005
6210 Tubulin delta chain TUBD1 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0005
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0004
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0004
4920 Peroxidase/catalase katG 0.0004
2119 Cytochrome b5 CYB5A 0.0004
4990 PpcA ppcA 0.0004
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0004
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0004
3375 Acidic cytochrome c3 Not Available 0.0004
4988 Sulfite oxidase, mitochondrial SUOX 0.0004
2915 Sensor protein fixL fixL 0.0004
4944 Sensor protein fixL fixL 0.0004
4385 Cytochrome c' Not Available 0.0004
4967 Cytochrome c' cycA 0.0004
5038 Cytochrome c' Not Available 0.0004
5223 Cytochrome c' cycP 0.0004
3570 Cytochrome P450 152A1 cypC 0.0004
4813 Heme oxygenase hmuO 0.0004
5769 Heme oxygenase Not Available 0.0004
4037 Hypothetical protein GPX1 0.0004
4297 Hypothetical protein SP_1951 0.0004
4521 Hypothetical protein BC_2969 0.0004
4540 Hypothetical protein TM_1070 0.0004
4555 Hypothetical protein MT1739 0.0004
4569 Hypothetical protein mshD 0.0004
4578 Hypothetical protein PA3270 0.0004
4747 Hypothetical protein PA3967 0.0004
5177 Hypothetical protein TM_0096 0.0004
5194 Hypothetical protein PA1204 0.0004
5240 Hypothetical protein Rv2991 0.0004
5370 Hypothetical protein TM_1158 0.0004
5710 Hypothetical protein Tb927.5.1360 0.0004
4289 Cytochrome P450 TT_P0059 0.0004
6262 Cytochrome P450 staP 0.0004
4992 Cytochrome c peroxidase Not Available 0.0004
2216 Fibroblast growth factor receptor 4 FGFR4 0.0004
3670 Soluble cytochrome b562 precursor cybC 0.0004
3291 Cytochrome c-552 cycA 0.0004
4927 Cytochrome c-552 nrfA 0.0004
4938 Cytochrome c-552 cycA 0.0004
4953 Cytochrome c-552 nrfA 0.0004
5217 Cytochrome c-552 cycM 0.0004
2617 Nitric oxide synthase oxygenase nos 0.0004
2701 Nitric oxide synthase oxygenase nos 0.0004
3102 Flavohemoprotein hmp 0.0004
4969 Flavohemoprotein hmp 0.0004
594 Thyroxine-binding globulin SERPINA7 0.0004
758 Thyroid hormone receptor alpha THRA 0.0003
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0003
2972 6-deoxyerythronolide B hydroxylase eryF 0.0003
2240 Cell division protein kinase 2 CDK2 0.0003
199 Monocarboxylate transporter 8 SLC16A2 0.0003
4608 Putative cytochrome P450 SCO1207 0.0003
4963 Putative cytochrome P450 SCO2884 0.0003
6254 Putative cytochrome P450 SCO6998 0.0003
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0003
346 Thyroid hormone receptor beta-1 THRB 0.0003
693 Hemoglobin subunit beta HBB 0.0003
6268 Hydroxyacid oxidase 1 HAO1 0.0003
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