Name |
Metabotropic glutamate receptor 2 |
Synonyms |
3158 |
Gene name |
GRM2 |
General function |
Amino acid transport and metabolism |
Specific function |
Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization |
Gene sequence |
+ ...
ATGGGATCGCTGCTTGCGCTCCTGGCACTGCTGCCGCTGTGGGGTGCTGTGGCTGAGGGCCCAGCCAAGAAGGTGCTGACCCTGGAGGGAGACTTGGTGCTGGGTGGGCTGTTCCCAGTGCACCAGAAGGGCGGCCCAGCAGAGGACTGTGGTCCTGTCAATGAGCACCGTGGCATCCAGCGCCTGGAGGCCATGCTTTTTGCACTGGACCGCATCAACCGTGACCCGCACCTGCTGCCTGGCGTGCGCCTGGGTGCACACATCCTCGACAGTTGCTCCAAGGACACACATGCGCTGGAGCAGGCACTGGACTTTGTGCGTGCCTCACTCAGCCGTGGTGCTGATGGATCACGCCACATCTGCCCCGACGGCTCTTATGCGACCCATGGTGATGCTCCCACTGCCATCACTGGTGTTATTGGCGGTTCCTACAGTGATGTCTCCATCCAGGTGGCCAACCTCTTGAGGCTATTTCAGATCCCACAGATTAGCTACGCCTCTACCAGTGCCAAGCTGAGTGACAAGTCCCGCTATGACTACTTTGCCCGCACAGTGCCTCCTGACTTCTTCCAAGCCAAGGCCATGGCTGAGATTCTCCGCTTCTTCAACTGGACCTATGTGTCCACTGAGGCCTCTGAGGGCGACTATGGCGAGACAGGCATTGAGGCCTTTGAGCTAGAGGCTCGTGCCCGCAACATCTGTGTGGCCACCTCGGAGAAAGTGGGCCGTGCCATGAGCCGCGCGGCCTTTGAGGGTGTGGTGCGAGCCCTGCTGCAGAAGCCCAGTGCCCGCGTGGCTGTCCTGTTCACCCGTTCTGAGGATGCCCGGGAGCTGCTTGCTGCCAGCCAGCGCCTCAATGCCAGCTTCACCTGGGTGGCCAGTGATGGTTGGGGGGCCCTGGAGAGTGTGGTGGCAGGCAGTGAGGGGGCTGCTGAGGGTGCTATCACCATCGAGCTGGCCTCCTACCCCATCAGTGACTTTGCCTCCTACTTCCAGAGCCTGGACCCTTGGAACAACAGCCGGAACCCCTGGTTCCGTGAATTCTGGGAGCAGAGGTTCCGCTGCAGCTTCCGGCAGCGAGACTGCGCAGCCCACTCTCTCCGGGCTGTGCCCTTTGAACAGGAGTCCAAGATCATGTTTGTGGTCAATGCAGTGTACGCCATGGCCCATGCGCTCCACAACATGCACCGTGCCCTCTGCCCCAACACCACCCGGCTCTGTGACGCGATGCGGCCAGTTAACGGGCGCCGCCTCTACAAGGACTTTGTGCTCAACGTCAAGTTTGATGCCCCCTTTCGCCCAGCTGACACCCACAATGAGGTCCGCTTTGACCGCTTTGGTGATGGTATTGGCCGCTACAACATCTTCACCTATCTGCGTGCAGGCAGTGGGCGCTATCGCTACCAGAAGGTGGGCTACTGGGCAGAAGGCTTGACTCTGGACACCAGCCTCATCCCATGGGCCTCACCGTCAGCCGGCCCCCTGGCCGCCTCTCGCTGCAGTGAGCCCTGCCTCCAGAATGAGGTGAAGAGTGTGCAGCCGGGCGAAGTCTGCTGCTGGCTCTGCATTCCGTGCCAGCCCTATGAGTACCGATTGGACGAATTCACTTGCGCTGATTGTGGCCTGGGCTACTGGCCCAATGCCAGCCTGACTGGCTGCTTCGAACTGCCCCAGGAGTACATCCGCTGGGGCGATGCCTGGGCTGTGGGACCTGTCACCATCGCCTGCCTCGGTGCCCTGGCCACCCTGTTTGTGCTGGGTGTCTTTGTGCGGCACAATGCCACACCAGTGGTCAAGGCCTCAGGTCGGGAGCTCTGCTACATCCTGCTGGGTGGTGTCTTCCTCTGCTACTGCATGACCTTCATCTTCATTGCCAAGCCATCCACGGCAGTGTGTACCTTACGGCGTCTTGGTTTGGGCACTGCCTTCTCTGTCTGCTACTCAGCCCTGCTCACCAAGACCAACCGCATTGCACGCATCTTCGGTGGGGCCCGGGAGGGTGCCCAGCGGCCACGCTTCATCAGTCCTGCCTCACAGGTGGCCATCTGCCTGGCACTTATCTCGGGCCAGCTGCTCATCGTGGTCGCCTGGCTGGTGGTGGAGGCACCGGGCACAGGCAAGGAGACAGCCCCCGAACGGCGGGAGGTGGTGACACTGCGCTGCAACCACCGCGATGCAAGTATGTTGGGCTCGCTGGCCTACAATGTGCTCCTCATCGCGCTCTGCACGCTTTATGCCTTCAATACTCGCAAGTGCCCCGAAAACTTCAACGAGGCCAAGTTCATTGGCTTCACCATGTACACCACCTGCATCATCTGGCTGGCATTGTTGCCCATCTTCTATGTCACCTCCAGTGACTACCGGGTACAGACCACCACCATGTGCGTGTCAGTCAGCCTCAGCGGCTCCGTGGTGCTTGGCTGCCTCTTTGCGCCCAAGCTGCACATCATCCTCTTCCAGCCGCAGAAGAACGTGGTTAGCCACCGGGCACCCACCAGCCGCTTTGGCAGTGCTGCTGCCAGGGCCAGCTCCAGCCTTGGCCAAGGGTCTGGCTCCCAGTTTGTCCCCACTGTTTGCAATGGCCGTGAGGTGGTGGACTCGACAACGTCATCGCTTTGA
|
Protein sequence |
+ ...
MGSLLALLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRLYKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARIFGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAARASSSLGQGSGSQFVPTVCNGREVVDSTTSSL
|
GO Classification |
component |
cell |
membrane |
function |
signal transducer activity |
receptor activity |
transmembrane receptor activity |
G-protein coupled receptor activity |
metabotropic glutamate, GABA-B-like receptor activity |
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