DT-Web

DB03085 - Hydroxyacetic Acid


Identification
Name Hydroxyacetic Acid
Accession Number DB03085 (EXPT01629)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 76.0514
Groups experimental
Monoisotopic Weight 76.016043994
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Glucose-6-phosphate 1-dehydrogenase
Name Glucose-6-phosphate 1-dehydrogenase
Gene Name G6PD
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.825
Glycine oxidase
Name Glycine oxidase
Gene Name thiO
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.4009

Predictions


Id Partner name Gene Name Score
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.825
5073 Ferredoxin--NADP reductase petH 0.0224
5076 Ferredoxin--NADP reductase fpr 0.0224
5119 Ferredoxin--NADP reductase petH 0.0224
5121 Ferredoxin--NADP reductase fpr 0.0224
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0224
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0195
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0169
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0169
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0169
5332 MtdA bifunctional protein mtdA 0.0169
4403 Protein iolS iolS 0.0169
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0169
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0169
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0169
3778 NAD(P) transhydrogenase subunit beta pntB 0.0169
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0169
5322 Oxidoreductase ydhF ydhF 0.0169
5330 General stress protein 69 yhdN 0.0169
5328 Prostaglandin F synthase Tb11.02.2310 0.0147
989 L-xylulose reductase DCXR 0.0147
2636 Shikimate dehydrogenase aroE 0.0147
3515 Shikimate dehydrogenase aroE 0.0147
4582 Putative pteridine reductase 2 ptr2 0.0147
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0147
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.0147
729 GDP-L-fucose synthetase TSTA3 0.0147
3463 GDP-L-fucose synthetase fcl 0.0147
3446 NADP-dependent alcohol dehydrogenase adh 0.0147
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0147
2286 Isocitrate dehydrogenase [NADP] icd 0.0147
2302 Isocitrate dehydrogenase [NADP] icd 0.0147
2771 Isocitrate dehydrogenase [NADP] icd 0.0147
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0147
4531 Putative ketoacyl reductase actIII 0.0135
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.0135
6297 Prostaglandin reductase 1 PTGR1 0.0135
3062 Aspartate-semialdehyde dehydrogenase asd 0.0135
76 Nitric-oxide synthase, brain NOS1 0.013
1124 Sepiapterin reductase SPR 0.0128
2675 Pteridine reductase 1 PTR1 0.0128
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0128
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0126
666 NADP-dependent malic enzyme ME1 0.0126
646 Malate dehydrogenase, cytoplasmic MDH1 0.0122
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0122
2159 Quinone oxidoreductase CRYZ 0.0117
4120 NADPH--cytochrome P450 reductase POR 0.0114
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0106
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0106
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0106
654 Flavin reductase BLVRB 0.0104
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0098
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0096
444 Alcohol dehydrogenase 1B ADH1B 0.0095
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0091
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0091
5095 Putidaredoxin reductase camA 0.0088
5109 Outer membrane protein p64k or PM-6 m-6 0.0088
526 Thioredoxin reductase trxB 0.0088
3767 Thioredoxin reductase trxB 0.0088
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0088
5078 Amine oxidase, flavin-containing PSPTO1126 0.0088
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0088
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0088
5122 Mersacidin decarboxylase mrsD 0.0088
5111 Phenylacetone monooxygenase pamO 0.0088
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0088
5115 FkbI fkbI 0.0088
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0088
5083 Cryptochrome DASH cry 0.0088
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0088
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0088
3763 5,10-methylenetetrahydrofolate reductase metF 0.0088
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0088
5094 5,10-methylenetetrahydrofolate reductase metF 0.0088
5081 L-aspartate oxidase nadB 0.0088
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0088
3133 UDP-galactopyranose mutase glf 0.0088
5099 UDP-galactopyranose mutase glf 0.0088
1410 Oxidoreductase HSD17B6 0.0088
4725 Oxidoreductase Not Available 0.0088
5124 Oxidoreductase Not Available 0.0088
822 Aldose reductase AKR1B1 0.0084
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0079
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0079
365 Dihydrofolate reductase DHFR 0.0078
2381 Dihydrofolate reductase DFR1 0.0078
2833 Dihydrofolate reductase Not Available 0.0078
2931 Dihydrofolate reductase folA 0.0078
3544 Dihydrofolate reductase folA 0.0078
3682 Dihydrofolate reductase folA 0.0078
6642 Dihydrofolate reductase folA 0.0078
6756 Dihydrofolate reductase dfrA 0.0078
4486 Phenol 2-hydroxylase component B pheA2 0.0077
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0077
4439 Ferredoxin reductase bphA4 0.0077
2526 NADPH-ferredoxin reductase fprA fprA 0.0077
2268 Cholesterol oxidase choB 0.0077
2822 Cholesterol oxidase choA 0.0077
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0077
3594 Deoxyribodipyrimidine photo-lyase phr 0.0077
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0077
5080 Deoxyribodipyrimidine photo-lyase phr 0.0077
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0077
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0077
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0077
4477 Dihydrolipoyl dehydrogenase lpdV 0.0077
5077 Dihydrolipoyl dehydrogenase Not Available 0.0077
5117 Dihydrolipoyl dehydrogenase lpd 0.0077
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0077
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0077
5072 N,N-dimethylglycine oxidase dmg 0.0077
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0077
2470 Pyruvate oxidase pox5 0.0077
4440 NADH peroxidase npr 0.0071
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0071
3102 Flavohemoprotein hmp 0.0071
4969 Flavohemoprotein hmp 0.0071
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0071
2567 Thymidylate synthase thyX thyX 0.0067
2823 Trypanothione reductase TPR 0.0067
2769 P-hydroxybenzoate hydroxylase pobA 0.0064
2809 P-hydroxybenzoate hydroxylase pobA 0.0064
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0063
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0063
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0063
2380 Monomeric sarcosine oxidase soxA 0.0062
327 Glutathione reductase gor 0.0062
5110 Glutathione reductase GR2 0.0062
126 D-lactate dehydrogenase dld 0.0061
3545 D-lactate dehydrogenase Not Available 0.0061
4510 D-lactate dehydrogenase ldhA 0.0061
605 Fumarate reductase flavoprotein subunit frdA 0.006
2709 Fumarate reductase flavoprotein subunit SO_0970 0.006
3673 Fumarate reductase flavoprotein subunit fccA 0.006
4912 Fumarate reductase flavoprotein subunit ifcA 0.006
6549 Fumarate reductase flavoprotein subunit frdA 0.006
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0059
6645 D-amino-acid oxidase DAO 0.0058
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0052
714 Glutathione reductase, mitochondrial GSR 0.0047
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0047
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0042
3939 Amine oxidase [flavin-containing] B MAOB 0.0034
3947 Xanthine dehydrogenase/oxidase XDH 0.0033
3941 Amine oxidase [flavin-containing] A MAOA 0.003
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