DT-Web

Thymidylate synthase thyX


Partner ID 2567
Name Thymidylate synthase thyX
Synonyms 78
Gene name thyX
General function Nucleotide transport and metabolism
Specific function Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate
Gene sequence + ...

TCATACCTGTACCTCCTTCAGGATATCTCCTTTATAAGCATACTTAAGAAATGCCTCAAAAGTCCAGGGACACTTCTCTTTGAAAATTCTCGCGATTGCCAGAGCGTACTGTTGAATTTCCCACTGAGCGTGAGAATCTGCCCTCAGGTTCAAAAAGTTCATGAGACTTCTTGCGTTCACAGTCCAGAAAAACCTCGTGTACAGATTCAAAGGGAGCACTATCCTTGCCACTTCTCGAGGAACACCGCTTTCTATCAACTCCAGATACGTTCGATACGCTTTATCGACTATTTCTGAGATCTTCTCCGTCACCCGTTCGGGAGGGATGGTCGTTTTGTACCCTTCCAGGCGTTCGGGAGAGGGAATGTAGAATTCGTAGGAGAGCTTCGAGTATCTGCCGCTCAGTTCGTTGTAAGAAGCGATCCTGTGTCTGAACCACTGCCTCGCCACGAATATAGGGGCTTTCACGTGGAAAGTGAAGACAATATGTTCGAAAGGTGTCTCGTGACCGTGTTTCATGAGATATTCGATGAGATGTCTATCCCTTTCTTCGTCTTTCAAACCCATATCGAAAGAAACGCGGGCAGCCCGTACAGCGGAGAGGTCGTTTCCCATCACATCCACAAGTTCAACGAATCCTTTGTCCAAGATATCGATCTTCAT
Protein sequence + ...

MKIDILDKGFVELVDVMGNDLSAVRAARVSFDMGLKDEERDRHLIEYLMKHGHETPFEHIVFTFHVKAPIFVARQWFRHRIASYNELSGRYSKLSYEFYIPSPERLEGYKTTIPPERVTEKISEIVDKAYRTYLELIESGVPREVARIVLPLNLYTRFFWTVNARSLMNFLNLRADSHAQWEIQQYALAIARIFKEKCPWTFEAFLKYAYKGDILKEVQV
GO Classification Not Available
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB01903 5-Bromo-2'-Deoxyuridine-5'-Monophosphate
DB03147 Flavin-Adenine Dinucleotide
DB03761 5-Fluoro-2'-Deoxyuridine-5'-Monophosphate
DB03800 2'-deoxyuridylic acid

Associated as Prediction

Id Name
DB00041 Aldesleukin
DB00127 Spermine
DB00140 Riboflavin
DB00143 Glutathione
DB00155 L-Citrulline
DB00157 NADH
DB00163 Vitamin E
DB00166 Lipoic Acid
DB00170 Menadione
DB00184 Nicotine
DB00191 Phentermine
DB00262 Carmustine
DB00266 Dicumarol
DB00293 Raltitrexed
DB00305 Mitomycin
DB00315 Zolmitriptan
DB00322 Floxuridine
DB00336 Nitrofurazone
DB00339 Pyrazinamide
DB00388 Phenylephrine
DB00397 Phenylpropanolamine
DB00432 Trifluridine
DB00437 Allopurinol
DB00440 Trimethoprim
DB00441 Gemcitabine
DB00515 Cisplatin
DB00518 Albendazole
DB00526 Oxaliplatin
DB00544 Fluorouracil
DB00563 Methotrexate
DB00583 L-Carnitine
DB00601 Linezolid
DB00614 Furazolidone
DB00624 Testosterone
DB00642 Pemetrexed
DB00650 Leucovorin
DB00665 Nilutamide
DB00669 Sumatriptan
DB00694 Daunorubicin
DB00698 Nitrofurantoin
DB00746 Deferoxamine
DB00752 Tranylcypromine
DB00756 Hexachlorophene
DB00780 Phenelzine
DB00805 Minaprine
DB00831 Trifluoperazine
DB00852 Pseudoephedrine
DB00856 Chlorphenesin
DB00865 Benzphetamine
DB00909 Zonisamide
DB00915 Amantadine
DB00918 Almotriptan
DB00952 Naratriptan
DB00953 Rizatriptan
DB00958 Carboplatin
DB00988 Dopamine
DB00993 Azathioprine
DB00997 Doxorubicin
DB01033 Mercaptopurine
DB01037 Selegiline
DB01065 Melatonin
DB01087 Primaquine
DB01101 Capecitabine
DB01104 Sertraline
DB01136 Carvedilol
DB01168 Procarbazine
DB01169 Arsenic trioxide
DB01171 Moclobemide
DB01247 Isocarboxazid
DB01363 Ephedra
DB01367 Rasagiline
DB01442 MMDA
DB01445 Bufotenine
DB01466 Ethylmorphine
DB01472 4-Methoxyamphetamine
DB01577 Methamphetamine
DB01626 Pargyline
DB01643 Thymidine-5'-Phosphate
DB01644 3,6-Dihydroxy-Xanthene-9-Propionic Acid
DB01675 Methacrylyl-Coenzyme A
DB01677 Fumarate
DB01685 4-[5-Pyridin-4-Yl-1h-[1,2,4]Triazol-3-Yl]-Pyridine-2-Carbonitrile
DB01708 Dehydroepiandrosterone
DB01753 4-Oxo-Nicotinamide-Adenine Dinucleotide Phosphate
DB01821 L-N(Omega)-Nitroarginine-2,4-L-Diaminobutyric Amide
DB01891 Tl-3-093
DB01903 5-Bromo-2'-Deoxyuridine-5'-Monophosphate
DB01907 Nicotinamide-Adenine-Dinucleotide
DB01918 [Methyltelluro]Acetate
DB01927 Duroquinone
DB01942 Formic Acid
DB01965 2'-Deoxyuridine 5'-Alpha,Beta-Imido-Triphosphate
DB01987 Thiamin Diphosphate
DB01997 3-Bromo-7-Nitroindazole
DB02027 N-{(4s)-4-Amino-5-[(2-Aminoethyl)Amino]Pentyl}-N'-Nitroguanidine
DB02031 (6s)-5,6,7,8-Tetrahydrofolate
DB02044 N-(3-(Aminomethyl)Benzyl)Acetamidine
DB02059 Adenosine-5-Diphosphoribose
DB02077 L-N(Omega)-Nitroarginine-(4r)-Amino-L-Proline Amide
DB02083 Dimethylglycine
DB02095 Isatin
DB02143 N-Isopropyl-N'-Hydroxyguanidine
DB02153 3-Sulfinoalanine
DB02211 N-Methyl-N-Propargyl-1(R)-Aminoindan
DB02223 Ly231514 Tetra Glu
DB02240 N-{(1s)-4-[Bis(2-Chloroethyl)Amino]-1-Methylbutyl}-N-(6-Chloro-2-Methoxy-9-Acridinyl)Amine
DB02256 2'-Deoxyuridine
DB02301 5,10-Methylene-6-Hydrofolic Acid
DB02303 (5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione
DB02332 Flavin-N7 Protonated-Adenine Dinucleotide
DB02333 Deoxyuridine-5'-Triphosphate
DB02338 Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate
DB02362 4-Aminobenzoic Acid
DB02395 3-Hydroxymethyl-5-Aziridinyl-1methyl-2-[1h-Indole-4,7-Dione]-Propanol
DB02400 5-Methoxy-1,2-Dimethyl-3-(4-Nitrophenoxymethyl)Indole-4,7-Dione
DB02467 S-Oxymethionine
DB02509 Farnesol
DB02543 Pyrrole-2-Carboxylate
DB02553 Glutathionylspermidine Disulfide
DB02633 Cibacron Blue
DB02643 N-Dodecyl-N,N-Dimethyl-3-Ammonio-1-Propanesulfonate
DB02644 N-Omega-Propyl-L-Arginine
DB02692 (6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin
DB02709 Resveratrol
DB02713 Acetylamino-Acetic Acid
DB02727 N-Butyl-N'-Hydroxyguanidine
DB02752 Tosyl-D-Proline
DB02838 3,4-Dihydro-2h-Pyrrolium-5-Carboxylate
DB02839 2,4-Dihydroxybenzoic Acid
DB02895 3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol
DB02899 N-Carboxymethionine
DB02910 Octanoyl-Coenzyme A
DB02939 [(1e)-4-Phenylbut-1-Enyl]Benzene
DB02944 Alpha-D-Mannose
DB02988 Imino-Tryptophan
DB02991 S-Ethyl-N-[4-(Trifluoromethyl)Phenyl]Isothiourea
DB03014 Heme
DB03038 LY341770
DB03048 6-Carboxymethyluracil
DB03051 Tetrahydrofuran-2-Carboxylic Acid
DB03059 Acetoacetyl-Coenzyme A
DB03085 Hydroxyacetic Acid
DB03098 [Methylseleno]Acetate
DB03144 N-Omega-Hydroxy-L-Arginine
DB03147 Flavin-Adenine Dinucleotide
DB03157 N,O-Didansyl-L-Tyrosine
DB03163 (2-[2-Ketopropylthio]Ethanesulfonate
DB03225 D-Tryptophan
DB03245 S-4-Nitrobutyryl-Coa
DB03247 Riboflavin Monophosphate
DB03256 5-Formyl-5,6,7,8-Tetrahydrofolate
DB03274 2'-5'dideoxyuridine
DB03310 Oxidized Glutathione Disulfide
DB03328 dioxothiomolybdenum(VI) ion
DB03343 Malate Like Intermediate
DB03382 S-Oxy Cysteine
DB03413 Deoxyuridine-5'-Diphosphate
DB03415 3-Thiaoctanoyl-Coenzyme A
DB03419 Uracil
DB03435 Uridine-5'-Diphosphate
DB03449 N-(4-(2-((3-Chlorophenylmethyl)Amino)Ethyl)Phenyl)-2-Thiophecarboxamidine
DB03461 2'-Monophosphoadenosine 5'-Diphosphoribose
DB03462 Thymine
DB03470 Trypanothione
DB03482 8-Demethyl-8-Dimethylamino-Flavin-Adenine-Dinucleotide
DB03517 [Methylthio]Acetate
DB03531 Flavin-Adenine Dinucleotide-N5-Isobutyl Ketone
DB03541 10-Propargyl-5,8-Dideazafolic Acid
DB03554 5-Iodouracil
DB03558 Sp-876
DB03566 Spermidine
DB03626 5-Methoxy-1,2-Dimethyl-3-(Phenoxymethyl)Indole-4,7-Dione
DB03685 Uridine-5'-Monophosphate
DB03698 5-Mercaptoethanol-2-Decenoyl-Coenzyme A
DB03707 S-Ethyl-N-Phenyl-Isothiourea
DB03709 Bicine
DB03710 N5-(1-Imino-3-Butenyl)-L-Ornithine
DB03761 5-Fluoro-2'-Deoxyuridine-5'-Monophosphate
DB03793 Benzoic Acid
DB03798 2'-Deoxycytidine-5'-Monophosphate
DB03800 2'-deoxyuridylic acid
DB03818 N-[Tosyl-D-Prolinyl]Amino-Ethanethiol
DB03841 Y-700
DB03867 Meta-Nitro-Tyrosine
DB03892 5-N-Allyl-Arginine
DB03894 N-Propargyl-1(S)-Aminoindan
DB03979 1-[Glycerolylphosphonyl]-2-[8-(2-Hexyl-Cyclopropyl)-Octanal-1-Yl]-3-[Hexadecanal-1-Yl]-Glycerol
DB04017 N-Methyl-N-Propargyl-3-(2,4-Dichlorophenoxy)Propylamine
DB04036 Coenzyme a Persulfide
DB04090 2,5-Diaziridin-1-Yl-3-(Hydroxymethyl)-6-Methylcyclohexa-2,5-Diene-1,4-Dione
DB04106 Fotemustine
DB04147 Lauryl Dimethylamine-N-Oxide
DB04166 2-Aminobenzoic Acid
DB04223 Nitroarginine
DB04242 P-Hydroxybenzoic Acid
DB04253 CB1954
DB04299 Maleic Acid
DB04307 5-Hydroxy-N-Propargyl-1(R)-Aminoindan
DB04392 Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone]
DB04398 Lactic Acid
DB04447 1,4-Dithiothreitol
DB04457 2'-Deoxyguanosine-5'-Monophosphate
DB04503 Sp-722
DB04530 S,S-(2-Hydroxyethyl)Thiocysteine
DB04586 2-bromophenol
DB04677 N-METHYL-N-[(1R)-1-METHYL-2-PHENYLETHYL]PROP-2-EN-1-AMINE
DB04696 4-CHLORO-3',3''-DIBROMOPHENOL-1,8-NAPHTHALEIN
DB04734 Citraconic acid
DB04818 Iproniazid
DB04820 Nialamide
DB04821 Nomifensine
DB04832 Zimelidine
DB06695 Dabigatran etexilate
DB06813 Pralatrexate
DB06860 2-(2-chloropyridin-4-yl)-4-methyl-1H-isoindole-1,3(2H)-dione
DB07296 (5Z)-3-(4-CHLOROPHENYL)-4-HYDROXY-5-(1-NAPHTHYLMETHYLENE)FURAN-2(5H)-ONE
DB07339 (3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione
DB07365 NAPHTHALEN-2-YL-3-ALANINE
DB07385 3-(HYDROXYMETHYL)-1-METHYL-5-(2-METHYLAZIRIDIN-1-YL)-2-PHENYL-1H-INDOLE-4,7-DIONE
DB07393 2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE
DB07507 2-(4-hydroxybiphenyl-3-yl)-4-methyl-1H-isoindole-1,3(2H)-dione
DB07511 4-(4-methyl-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzonitrile
DB07512 7-[(3-CHLOROBENZYL)OXY]-2-OXO-2H-CHROMENE-4-CARBALDEHYDE
DB07513 7-[(3-CHLOROBENZYL)OXY]-4-[(METHYLAMINO)METHYL]-2H-CHROMEN-2-ONE
DB07577 6-ETHYL-5-PHENYLPYRIMIDINE-2,4-DIAMINE
DB07641 DECYL(DIMETHYL)PHOSPHINE OXIDE
DB07714 6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID
DB07919 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE
DB07930 (3R)-3-HYDROXYDODECANOIC ACID
DB07979 (2E)-3-(3,4-DIHYDROXYPHENYL)-2-IMINOPROPANOIC ACID
DB08018 N-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE
DB08019 N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine
DB08082 N-(2-AMINOETHYL)-P-CHLOROBENZAMIDE
DB08131 2-{4-[2-(2-AMINO-4-OXO-4,7-DIHYDRO-3H-PYRROLO[2,3-D]PYRIMIDIN-5-YL)-ETHYL]-BENZOYLAMINO}-3-METHYL-BUTYRIC ACID
DB08176 (1Z)-4-(4-FLUOROPHENYL)-2-METHYLIDENEBUTAN-1-IMINE
DB08190 N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide
DB08204 3-DIPHENOL-6-NITRO-3H-BENZO[DE]ISOCHROMEN-1-ONE
DB08228 5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one
DB08253 NAM NAPTHYLAMINOALANINE
DB08478 N-[2-chloro-5-(trifluoromethyl)phenyl]imidodicarbonimidic diamide
DB08479 N-(3,5-dimethoxyphenyl)imidodicarbonimidic diamide
DB08480 4-HYDROXY-N-PROPARGYL-1(R)-AMINOINDAN
DB08516 (S)-(+)-2-[4-(FLUOROBENZYLOXY-BENZYLAMINO)PROPIONAMIDE]
DB08734 6,6-DIMETHYL-1-[3-(2,4,5-TRICHLOROPHENOXY)PROPOXY]-1,6-DIHYDRO-1,3,5-TRIAZINE-2,4-DIAMINE
DB08744 6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one
DB08804 Nandrolone decanoate
↑