DT-Web

DB03059 - Acetoacetyl-Coenzyme A


Identification
Name Acetoacetyl-Coenzyme A
Accession Number DB03059 (EXPT00820)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 851.607
Groups experimental
Monoisotopic Weight 851.136337737
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


PROBABLE NAPHTHOATE SYNTHASE MENB
Name PROBABLE NAPHTHOATE SYNTHASE MENB
Gene Name menB
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.6931
Acyl-CoA dehydrogenase, short-chain specific
Name Acyl-CoA dehydrogenase, short-chain specific
Gene Name Not Available
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.6824
HMG-CoA synthase
Name HMG-CoA synthase
Gene Name mvaS
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.7493
3-hydroxy-3-methylglutaryl CoA synthase
Name 3-hydroxy-3-methylglutaryl CoA synthase
Gene Name mvaS
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.1554
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
Name Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
Gene Name HADH
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0274
Acetyl-CoA acetyltransferase
Name Acetyl-CoA acetyltransferase
Gene Name phbA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.7779
Short-chain specific acyl-CoA dehydrogenase, mitochondrial
Name Short-chain specific acyl-CoA dehydrogenase, mitochondrial
Gene Name ACADS
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.5886
Enoyl-CoA hydratase, mitochondrial
Name Enoyl-CoA hydratase, mitochondrial
Gene Name ECHS1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available

Predictions


Id Partner name Gene Name Score
615 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.2488
3138 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.2488
4568 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.2488
6370 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.2488
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.1369
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.1369
4602 Osmotically inducible protein C tthHB8IM 0.0753
2664 S-ribosylhomocysteine lyase luxS 0.0753
2725 S-ribosylhomocysteine lyase luxS 0.0753
2670 Pyridoxamine kinase pdxY 0.0753
2688 Peptide deformylase def 0.0656
2708 Peptide deformylase def 0.0656
3004 Peptide deformylase def 0.0656
4337 Peptide deformylase def 0.0656
4338 Peptide deformylase def 0.0656
5368 Peptide deformylase def 0.0656
5371 Peptide deformylase def 0.0656
6375 Peptide deformylase def 0.0656
6378 Peptide deformylase def 0.0656
6379 Peptide deformylase def 0.0656
6776 Peptide deformylase def 0.0656
6900 Peptide deformylase def 0.0656
3599 Peroxiredoxin-2 PRDX2 0.0656
2378 Carboxymethylenebutenolidase clcD 0.0655
2705 Dimethyl sulfoxide reductase dmsA 0.0655
2409 Acetyl-CoA acetyltransferase, cytosolic ACAT2 0.0629
2714 Chorismate mutase aroH 0.0604
4611 Chorismate mutase aroG 0.0604
2603 Beta-lactamase II blm 0.0604
714 Glutathione reductase, mitochondrial GSR 0.0573
4600 Malonamidase E2 Not Available 0.057
2183 Fatty acid-binding protein, adipocyte FABP4 0.0451
5898 Complement C3 C3 0.0351
4567 Putative acyl-CoA thioester hydrolase HI0827 HI_0827 0.0318
4564 YvbK protein yvbK 0.0318
4037 Hypothetical protein GPX1 0.0317
4297 Hypothetical protein SP_1951 0.0317
4521 Hypothetical protein BC_2969 0.0317
4540 Hypothetical protein TM_1070 0.0317
4555 Hypothetical protein MT1739 0.0317
4569 Hypothetical protein mshD 0.0317
4578 Hypothetical protein PA3270 0.0317
4747 Hypothetical protein PA3967 0.0317
5177 Hypothetical protein TM_0096 0.0317
5194 Hypothetical protein PA1204 0.0317
5240 Hypothetical protein Rv2991 0.0317
5370 Hypothetical protein TM_1158 0.0317
5710 Hypothetical protein Tb927.5.1360 0.0317
4576 Aac(6')-Ii protein aac(6')-Ii 0.0317
4566 Acyl-CoA hydrolase BC_2038 0.0317
4572 Acyl-CoA hydrolase BH0798 0.0317
2528 Fatty acid metabolism regulator protein fadR 0.0317
6740 Fatty acid metabolism regulator protein fadR 0.0317
4577 4'-phosphopantetheinyl transferase sfp sfp 0.0317
4579 Serine acetyltransferase cysE 0.0317
6807 Serine acetyltransferase cysE 0.0317
6677 Myelin P2 protein PMP2 0.0306
2517 Subtilisin BPN' apr 0.0292
4563 Acetyl transferase rimL 0.0276
3317 Holo-[acyl-carrier-protein] synthase acpS 0.0276
4381 Holo-[acyl-carrier-protein] synthase acpS 0.0276
4565 Aminoglycoside 6'-N-acetyltransferase aac(6')-Iy 0.0276
3125 Protease synthase and sporulation negative regulatory protein PAI 1 paiA 0.0276
3560 Gentamicin 3'-acetyltransferase aacC1 0.0276
3024 Crotonobetainyl-CoA:carnitine CoA-transferase caiB 0.0276
2396 Formyl-coenzyme A transferase frc 0.0276
3457 Formyl-coenzyme A transferase frc 0.0276
3489 Acetyl-coenzyme A synthetase acs 0.0276
3199 Phosphopantetheine adenylyltransferase coaD 0.0255
3543 Phosphopantetheine adenylyltransferase coaD 0.0255
3567 Phosphopantetheine adenylyltransferase coaD 0.0255
5289 Phosphopantetheine adenylyltransferase coaD 0.0255
2560 Galactoside O-acetyltransferase lacA 0.0255
2285 Streptogramin A acetyltransferase vatD 0.0255
2377 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Not Available 0.0255
3697 Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase glmU 0.0255
2248 Malate synthase G glcB 0.0255
3190 Malate synthase G glcB 0.0255
3178 Formate acetyltransferase 1 pflB 0.0255
4573 Histone acetyltransferase PCAF KAT2B 0.0255
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0252
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0252
2443 Azurin azu 0.0246
4404 FcbC1 protein fcbC 0.0241
2371 Pantothenate kinase coaA 0.0241
2376 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase dapD 0.023
4031 Glutathione S-transferase A1 GSTA1 0.0227
551 Carnitine O-acetyltransferase CRAT 0.0222
4486 Phenol 2-hydroxylase component B pheA2 0.0215
4439 Ferredoxin reductase bphA4 0.0215
4477 Dihydrolipoyl dehydrogenase lpdV 0.0215
5077 Dihydrolipoyl dehydrogenase Not Available 0.0215
5117 Dihydrolipoyl dehydrogenase lpd 0.0215
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0206
5122 Mersacidin decarboxylase mrsD 0.0205
5078 Amine oxidase, flavin-containing PSPTO1126 0.0205
3763 5,10-methylenetetrahydrofolate reductase metF 0.0205
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0205
5094 5,10-methylenetetrahydrofolate reductase metF 0.0205
5115 FkbI fkbI 0.0205
526 Thioredoxin reductase trxB 0.0205
3767 Thioredoxin reductase trxB 0.0205
5095 Putidaredoxin reductase camA 0.0205
3133 UDP-galactopyranose mutase glf 0.0205
5099 UDP-galactopyranose mutase glf 0.0205
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0205
1410 Oxidoreductase HSD17B6 0.0205
4725 Oxidoreductase Not Available 0.0205
5124 Oxidoreductase Not Available 0.0205
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0205
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0205
5083 Cryptochrome DASH cry 0.0205
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0205
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0205
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0205
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0205
5081 L-aspartate oxidase nadB 0.0205
5109 Outer membrane protein p64k or PM-6 m-6 0.0205
5111 Phenylacetone monooxygenase pamO 0.0205
4388 Aminoglycoside 2'-N-acetyltransferase aac 0.0195
4440 NADH peroxidase npr 0.0195
904 Glutathione S-transferase P GSTP1 0.0182
5073 Ferredoxin--NADP reductase petH 0.0179
5076 Ferredoxin--NADP reductase fpr 0.0179
5119 Ferredoxin--NADP reductase petH 0.0179
5121 Ferredoxin--NADP reductase fpr 0.0179
2526 NADPH-ferredoxin reductase fprA fprA 0.0179
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0179
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0178
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0178
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0178
2470 Pyruvate oxidase pox5 0.0176
3594 Deoxyribodipyrimidine photo-lyase phr 0.0176
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0176
5080 Deoxyribodipyrimidine photo-lyase phr 0.0176
5072 N,N-dimethylglycine oxidase dmg 0.0176
2268 Cholesterol oxidase choB 0.0176
2822 Cholesterol oxidase choA 0.0176
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0176
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0176
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0176
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0176
327 Glutathione reductase gor 0.0173
5110 Glutathione reductase GR2 0.0173
3102 Flavohemoprotein hmp 0.0165
4969 Flavohemoprotein hmp 0.0165
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0164
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0161
2893 Glycine oxidase thiO 0.0161
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0154
2567 Thymidylate synthase thyX thyX 0.0154
2823 Trypanothione reductase TPR 0.0152
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0152
2769 P-hydroxybenzoate hydroxylase pobA 0.0146
2809 P-hydroxybenzoate hydroxylase pobA 0.0146
126 D-lactate dehydrogenase dld 0.0144
3545 D-lactate dehydrogenase Not Available 0.0144
4510 D-lactate dehydrogenase ldhA 0.0144
605 Fumarate reductase flavoprotein subunit frdA 0.0142
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0142
3673 Fumarate reductase flavoprotein subunit fccA 0.0142
4912 Fumarate reductase flavoprotein subunit ifcA 0.0142
6549 Fumarate reductase flavoprotein subunit frdA 0.0142
2380 Monomeric sarcosine oxidase soxA 0.014
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0136
6645 D-amino-acid oxidase DAO 0.0132
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0121
3947 Xanthine dehydrogenase/oxidase XDH 0.0111
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0102
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0102
816 Biliverdin reductase A BLVRA 0.0102
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0102
76 Nitric-oxide synthase, brain NOS1 0.0102
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0097
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0095
646 Malate dehydrogenase, cytoplasmic MDH1 0.0095
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0094
328 Sorbitol dehydrogenase SORD 0.0093
597 Dihydropteridine reductase QDPR 0.0093
396 Alcohol dehydrogenase 4 ADH4 0.0093
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0093
4120 NADPH--cytochrome P450 reductase POR 0.0092
77 L-lactate dehydrogenase B chain LDHB 0.0087
12 Alcohol dehydrogenase class 3 ADH5 0.0087
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0085
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0085
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0085
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0085
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0085
473 L-lactate dehydrogenase A chain LDHA 0.0084
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0084
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.008
3939 Amine oxidase [flavin-containing] B MAOB 0.0079
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0079
569 Retinal dehydrogenase 2 ALDH1A2 0.0076
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.0075
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0075
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.0075
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.0075
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.0075
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.0075
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.0075
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.0075
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.0075
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.0075
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.0075
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.0075
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.0075
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.0075
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.0075
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.0075
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.0075
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.0075
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.0075
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.0075
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.0075
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.0075
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.0075
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.0075
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.0075
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.0075
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.0075
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.0075
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.0075
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.0075
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.0075
729 GDP-L-fucose synthetase TSTA3 0.0075
3463 GDP-L-fucose synthetase fcl 0.0075
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.0075
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.0075
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.0075
206 3-keto-steroid reductase HSD17B7 0.0075
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.0075
602 Acyl carrier protein, mitochondrial NDUFAB1 0.0075
107 C-4 methylsterol oxidase SC4MOL 0.0075
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.0075
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.0075
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.0075
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.0075
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.0075
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.0075
644 Heme oxygenase 2 HMOX2 0.0075
4982 Heme oxygenase 2 pbsA2 0.0075
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.0075
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.0075
167 L-lactate dehydrogenase C chain LDHC 0.0075
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.0075
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.0075
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.0075
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.0075
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.0075
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.0075
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.0075
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.0075
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.0075
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.0075
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.0075
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.0075
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.0075
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.0075
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.0075
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.0075
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.0075
662 Fatty aldehyde dehydrogenase ALDH3A2 0.0075
711 UDP-glucose 6-dehydrogenase UGDH 0.0075
3672 UDP-glucose 6-dehydrogenase hasB 0.0075
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.0075
643 Peroxisomal bifunctional enzyme EHHADH 0.0075
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.0075
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0075
3726 D-3-phosphoglycerate dehydrogenase serA 0.0075
4291 D-3-phosphoglycerate dehydrogenase serA 0.0075
34 7-dehydrocholesterol reductase DHCR7 0.0075
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.0075
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.0075
611 Retinal dehydrogenase 1 ALDH1A1 0.0074
251 Alcohol dehydrogenase 1A ADH1A 0.0072
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0072
3941 Amine oxidase [flavin-containing] A MAOA 0.0071
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.007
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0068
666 NADP-dependent malic enzyme ME1 0.0068
444 Alcohol dehydrogenase 1B ADH1B 0.0068
857 Malate dehydrogenase, mitochondrial MDH2 0.0065
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0064
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0062
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.006
517 Alcohol dehydrogenase 1C ADH1C 0.006
6026 Alcohol dehydrogenase 6 ADH6 0.006
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0057
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0057
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0057
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0057
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0057
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0057
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0056
627 11-cis retinol dehydrogenase RDH5 0.0056
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0056
626 Cysteine dioxygenase type 1 CDO1 0.0056
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0056
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0056
13 Aminomethyltransferase, mitochondrial AMT 0.0056
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0055
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0055
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0053
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0052
654 Flavin reductase BLVRB 0.0051
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.005
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0048
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0047
810 Heme oxygenase 1 HMOX1 0.0047
3391 Heme oxygenase 1 pbsA1 0.0047
279 Tyrosinase TYR 0.0046
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0046
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0045
380 Cytochrome P450 17A1 CYP17A1 0.0044
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0042
4449 ADP-ribosyltransferase Not Available 0.004
4471 CDP-D-glucose-4,6-dehydratase ascB 0.004
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.004
4435 L-aspartate dehydrogenase nadX 0.004
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.004
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.004
4472 Glucose 1-dehydrogenase Not Available 0.004
4423 Levodione reductase lvr 0.004
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.004
4455 Glycerol dehydrogenase gldA 0.004
4443 Quinate/shikimate dehydrogenase ydiB 0.004
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.004
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.004
4447 Hypothetical protein yhfP yhfP 0.004
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.004
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.004
3381 Alcohol dehydrogenase Not Available 0.004
4508 Alcohol dehydrogenase adhA 0.004
4414 Dehydrogenase TT_P0035 0.004
2350 3-isopropylmalate dehydrogenase leuB 0.004
3092 3-isopropylmalate dehydrogenase leuB 0.004
4507 Alanine dehydrogenase ald 0.004
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.004
4428 Redox-sensing transcriptional repressor rex rex 0.004
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.004
4502 Formate dehydrogenase Not Available 0.004
4487 Transcriptional regulator nadR nadR 0.004
3729 Citrate synthase gltA 0.004
4575 Citrate synthase cit 0.004
4580 Citrate synthase gltA 0.004
4451 Vip2Ac vip2Ac 0.004
4467 Alpha-glucosidase, putative TM_0752 0.004
4500 L-lactate dehydrogenase 2 ldh2 0.004
4418 AGR_L_3209p AGR_L_3209 0.004
4497 Benzyl alcohol dehydrogenase xylB 0.004
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.004
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.004
822 Aldose reductase AKR1B1 0.0038
365 Dihydrofolate reductase DHFR 0.0037
2381 Dihydrofolate reductase DFR1 0.0037
2833 Dihydrofolate reductase Not Available 0.0037
2931 Dihydrofolate reductase folA 0.0037
3544 Dihydrofolate reductase folA 0.0037
3682 Dihydrofolate reductase folA 0.0037
6642 Dihydrofolate reductase folA 0.0037
6756 Dihydrofolate reductase dfrA 0.0037
468 Cytochrome P450 4A11 CYP4A11 0.0036
6020 Aldehyde oxidase AOX1 0.0036
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0034
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.0034
4427 TDP-glucose-4,6-dehydratase desIV 0.0034
3177 dTDP-glucose 4,6-dehydratase rfbB 0.0034
4499 dTDP-glucose 4,6-dehydratase rmlB 0.0034
2967 CDP-paratose 2-epimerase rfbE 0.0033
4482 UDP-galactose 4-epimerase galE 0.0033
4503 NADPH-flavin oxidoreductase frp 0.0033
2507 Diphtheria toxin Not Available 0.0033
2538 6-phospho-beta-glucosidase bglT bglT 0.0033
2393 Maltose-6'-phosphate glucosidase glvA 0.0033
4509 Acetoin(diacetyl) reductase budC 0.0033
3081 3-dehydroquinate synthase aroB 0.0033
2591 Urocanate hydratase hutU 0.0033
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0033
3615 Dihydrodipicolinate reductase dapB 0.0033
3618 Dihydrodipicolinate reductase dapB 0.0033
4462 Dihydrodipicolinate reductase dapB 0.0033
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.0033
4450 Iota toxin component Ia Not Available 0.0033
2424 L-lactate dehydrogenase ldh 0.0033
2641 L-lactate dehydrogenase Not Available 0.0033
4437 L-lactate dehydrogenase ldh 0.0033
4442 L-lactate dehydrogenase ldh 0.0033
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.0033
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.0033
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.0033
3401 D-2-hydroxyisocaproate dehydrogenase Not Available 0.0033
2336 2,3-diketo-L-gulonate reductase dlgD 0.0033
4498 Ornithine cyclodeaminase PP3533 0.0033
2018 Deoxyhypusine synthase DHPS 0.0033
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0033
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0033
4496 C-terminal-binding protein 1 CTBP1 0.0033
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.0033
4504 WbpP Not Available 0.0031
2683 Mono-ADP-ribosyltransferase C3 C3 0.0031
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.0031
3367 GDP-mannose 6-dehydrogenase algD 0.003
4318 Siroheme synthase cysG 0.003
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.003
4343 Alpha-glucosidase aglA 0.003
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.003
63 Malate dehydrogenase mdh 0.0029
2329 Malate dehydrogenase mdh 0.0029
3445 Malate dehydrogenase mdh 0.0029
4420 Malate dehydrogenase mdh 0.0029
4438 Malate dehydrogenase mdh 0.0029
4476 Mannitol dehydrogenase mtlD 0.0029
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0029
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0029
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.0029
2434 NH(3)-dependent NAD(+) synthetase nadE 0.0029
2910 NH(3)-dependent NAD(+) synthetase nadE 0.0029
3217 NH(3)-dependent NAD(+) synthetase nadE 0.0029
2617 Nitric oxide synthase oxygenase nos 0.0029
2701 Nitric oxide synthase oxygenase nos 0.0029
2826 Glucose--fructose oxidoreductase gfo 0.0028
3070 Adenosylhomocysteinase AHCY 0.0028
4424 Adenosylhomocysteinase PFE1050w 0.0028
6278 Adenosylhomocysteinase ahcY 0.0028
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0028
3191 Histidinol dehydrogenase hisD 0.0028
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0027
2286 Isocitrate dehydrogenase [NADP] icd 0.0026
2302 Isocitrate dehydrogenase [NADP] icd 0.0026
2771 Isocitrate dehydrogenase [NADP] icd 0.0026
4491 DNA ligase, NAD-dependent ligA 0.0026
2762 UDP-glucose 4-epimerase GALE 0.0025
3461 UDP-glucose 4-epimerase galE 0.0025
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0021
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0021
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0021
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0021
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