DT-Web

Malonamidase E2


Partner ID 4600
Name Malonamidase E2
Synonyms 4547
Gene name Not Available
General function Involved in carbon-nitrogen ligase activity, with glutamine as amido-N-donor
Specific function Not Available
Gene sequence + ...

ATGATCTCACTCGCCGACCTCCAGCGCCGCATCGAAACGGGCGAGCTGTCGCCTAACGCAGCCATCGCCCAGTCGCACGCGGCGATCGAGGCGCGGGAGAAGGAGGTCCATGCCTTCGTCCGCCACGACAAGTCGGCAAGAGCGCAAGCCTCCGGCCCGCTGCGCGGTATCGCCGTCGGCATCAAGGACATCATCGACACCGCCAACATGCCCACCGAGATGGGCTCGGAGATCTATCGCGGCTGGCAGCCGCGCAGCGACGCGCCTGTCGTGATGATGCTGAAGCGGGCGGGGGCCACCATCATCGGCAAGACCACCACCACGGCGTTCGCCTCGCGCGATCCGACGGCGACGCTCAATCCGCACAATACCGGCCATTCCCCGGGCGGCTCGTCCTCGGGCTCGGCGGCGGCGGTCGGCGCCGGCATGATCCCGCTGGCGCTGGGCACCCAGACCGGCGGCTCGGTGATCCGGCCCGCCGCCTATTGCGGGACGGCCGCGATCAAGCCGTCGTTCCGCATGCTGCCGACGGTCGGCGTGAAGTGCTATTCGTGGGCGCTCGACACGGTCGGCCTGTTCGGCGCGCGCGCGGAGGATCTCGCGCGCGGACTGCTGGCGATGACCGGCCGCAGCGAATTCTCCGGCATCGTCCCGGCCAAGGCACCGCGCATCGGCGTGGTCAGGCAGGAGTTCGCCGGCGCTGTCGAGCCGGCGGCCGAGCAGGGCCTGCAAGCCGCGATCAAGGCGGCCGAGCGGGCCGGGGCCAGTGTTCAGGCCATCGATCTGCCCGAGGCGGTGCATGAGGCCTGGCGCATCCATCCCATCATCCAGGATTTCGAGGCGCATCGCGCGCTCGCCTGGGAGTTTTCCGAGCATCACGACGAGATCGCGCCGATGCTGCGCGCCAGTCTCGATGCGACGGTCGGGCTCACGCCGAAGGAATATGACGAGGCGCGCCGGATCGGCCGCCGTGGCCGCCGCGAGCTTGGCGAAGTGTTCGAGGGCGTCGACGTGCTCTTGACCTATTCGGCGCCGGGCACCGCGCCGGCCAAGGCTCTCGCGAGCACCGGCGACCCTCGCTACAACCGGCTCTGGACGCTGATGGGCAATCCTTGCGTCAACGTGCCGGTGCTGAAGGTCGGTGGCCTGCCGATCGGCGTGCAGGTGATCGCGCGCTTCGGCAACGACGCACATGCGCTTGCGACGGCGTGGTTCCTGGAGGATGCGCTGGCGAAATCAGGCTAG
Protein sequence + ...

MISLADLQRRIETGELSPNAAIAQSHAAIEAREKEVHAFVRHDKSARAQASGPLRGIAVGIKDIIDTANMPTEMGSEIYRGWQPRSDAPVVMMLKRAGATIIGKTTTTAFASRDPTATLNPHNTGHSPGGSSSGSAAAVGAGMIPLALGTQTGGSVIRPAAYCGTAAIKPSFRMLPTVGVKCYSWALDTVGLFGARAEDLARGLLAMTGRSEFSGIVPAKAPRIGVVRQEFAGAVEPAAEQGLQAAIKAAERAGASVQAIDLPEAVHEAWRIHPIIQDFEAHRALAWEFSEHHDEIAPMLRASLDATVGLTPKEYDEARRIGRRGRRELGEVFEGVDVLLTYSAPGTAPAKALASTGDPRYNRLWTLMGNPCVNVPVLKVGGLPIGVQVIARFGNDAHALATAWFLEDALAKSG
GO Classification
function
catalytic activity
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
amidase activity
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB02153 3-Sulfinoalanine
DB02175 Malonic acid
DB02212 Pyrophosphate 2-
DB02649 3-Amino-3-Oxopropanoic Acid

Associated as Prediction

Id Name
DB00143 Glutathione
DB00157 NADH
DB00262 Carmustine
DB00300 Tenofovir
DB00352 Thioguanine
DB00563 Methotrexate
DB00695 Furosemide
DB00709 Lamivudine
DB00718 Adefovir Dipivoxil
DB00789 Gadopentetate dimeglumine
DB00814 Meloxicam
DB00851 Dacarbazine
DB00867 Ritodrine
DB00920 Ketotifen
DB00993 Azathioprine
DB01033 Mercaptopurine
DB01254 Dasatinib
DB01632 Alpha-Phosphoribosylpyrophosphoric Acid
DB01644 3,6-Dihydroxy-Xanthene-9-Propionic Acid
DB01678 RU84687
DB01788 4-Imino-5-Methidyl-2-Methylpyrimidine
DB01866 RU79256
DB01893 N6-Benzyl Adenosine-5'-Diphosphate
DB01907 Nicotinamide-Adenine-Dinucleotide
DB01908 RU85493
DB01944 (S)-blebbistatin
DB01947 RU78262
DB01962 Phosphonotyrosine
DB01972 Guanosine-5'-Monophosphate
DB01973 O-Benzylsulfonyl-Serine
DB01992 Coenzyme A
DB02075 (1s)-1(9-Deazahypoxanthin-9yl)1,4-Dideoxy-1,4-Imino-D-Ribitol-5-Phosphate
DB02076 6-Phosphogluconic Acid
DB02153 3-Sulfinoalanine
DB02175 Malonic acid
DB02181 2'-Deoxyguanosine-5'-Triphosphate
DB02212 Pyrophosphate 2-
DB02254 Trifluoro-thiamin phosphate
DB02301 5,10-Methylene-6-Hydrofolic Acid
DB02309 5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine
DB02336 RU83876
DB02345 Selenocysteine
DB02379 Beta-D-Glucose
DB02432 RU90395
DB02475 Deoxyguanidinoproclavaminic acid
DB02521 2,5,7-Trihydroxynaphthoquinone
DB02553 Glutathionylspermidine Disulfide
DB02569 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate
DB02596 Alpha,Beta-Methyleneadenosine-5'-Triphosphate
DB02607 Adenosine Phosphonoacetic Acid
DB02649 3-Amino-3-Oxopropanoic Acid
DB02762 RU79072
DB02776 1-Hexadecanosulfonic Acid
DB02863 Alpha Chlorophyll A
DB02885 4-Imino-5-Methidyl-2-Trifluoromethylpyrimidine
DB02887 2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Triphosphate
DB02895 3-(Prop-2-Ene-1-Sulfinyl)-Propene-1-Thiol
DB02908 RU78783
DB02968 Penicillin G Acyl-Serine
DB03009 2-[(2-Oxo-2-Piperidin-1-Ylethyl)Thio]-6-(Trifluoromethyl)Pyrimidin-4(1h)-One
DB03014 Heme
DB03023 1-Tert-Butyl-3-(4-Chloro-Phenyl)-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine
DB03059 Acetoacetyl-Coenzyme A
DB03075 (Diphosphono)Aminophosphonic Acid
DB03078 PASBN
DB03088 Pyroglutamic Acid
DB03103 Thymidine-5'- Diphosphate
DB03104 RU82129
DB03114 PAS219
DB03126 Mant-Adp
DB03145 4-Methyl-5-Hydroxyethylthiazole Phosphate
DB03147 Flavin-Adenine Dinucleotide
DB03153 3h-Pyrazolo[4,3-D]Pyrimidin-7-Ol
DB03217 DPI59
DB03254 4-Phenyl-1h-Imidazole
DB03268 RU82197
DB03297 Benzylsulfinic Acid
DB03298 Phenylphosphate
DB03306 RU78300
DB03310 Oxidized Glutathione Disulfide
DB03382 S-Oxy Cysteine
DB03416 Thiamin Phosphate
DB03431 Adenosine-5'-Diphosphate
DB03491 2'-Deoxyguanosine-5'-Diphosphate
DB03525 RU79073
DB03530 Acylated Ceftazidime
DB03591 RU82209
DB03628 ISO24
DB03712 RU85053
DB03755 Adenosine-5'-[Beta, Gamma-Methylene]Tetraphosphate
DB03766 Propanoic Acid
DB03796 Palmitic Acid
DB03801 Lysine Nz-Carboxylic Acid
DB03814 2-(N-Morpholino)-Ethanesulfonic Acid
DB03828 RU78299
DB03851 Carbazole Butanoic Acid
DB03867 Meta-Nitro-Tyrosine
DB03902 Oxalic Acid
DB03909 Adenosine-5'-[Beta, Gamma-Methylene]Triphosphate
DB03962 Nicotinamide 8-Bromo-Adenine Dinucleotide Phosphate
DB04048 N-Carbamoyl-Alanine
DB04068 Fudp
DB04080 RU78191
DB04099 Deamido-Nad+
DB04137 Guanosine-5'-Triphosphate
DB04189 N2-(Carboxyethyl)-L-Arginine
DB04224 Oleic Acid
DB04272 Citric Acid
DB04310 2-[(Formyl-Hydroxy-Amino)-Methyl]-Heptanoic Acid [1-(2-Hydroxymethyl-Pyrrolidine-1-Carbonyl)-2-Methyl-Propyl]-Amide
DB04315 Guanosine-5'-Diphosphate
DB04349 S-1,2-Propanediol
DB04356 9-Deazaguanine
DB04366 3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate
DB04395 Phosphoaminophosphonic Acid-Adenylate Ester
DB04437 Cysteine-Methylene-Carbamoyl-1,10-Phenanthroline
DB04444 Tetrafluoroaluminate Ion
DB04474 1-Anilino-8-Naphthalene Sulfonate
DB04495 RU81843
DB04542 3'-Azido-3'-Deoxythymidine-5'-Diphosphate
DB04554 8-Bromoadenosine-5'-Diphosphate
DB04557 Arachidonic Acid
DB04739 4-[(4-METHYL-1-PIPERAZINYL)METHYL]-N-[3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-BENZAMIDE
DB04751 Purvalanol A
DB06616 Bosutinib
DB06882 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea
DB06883 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-phenylurea
DB07283 9-benzyl-2,3,4,9-tetrahydro-1H-carbazole-8-carboxylic acid
DB07335 3-[4-AMINO-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL]PHENOL
DB07393 2-(2-PHENYL-3-PYRIDIN-2-YL-4,5,6,7-TETRAHYDRO-2H-ISOPHOSPHINDOL-1-YL)PYRIDINE
DB07468 (3aS)-3a-hydroxy-5-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one
DB07469 (3aS)-3a-hydroxy-7-methyl-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one
DB07470 (3aS)-3a-hydroxy-1-phenyl-1,2,3,3a-tetrahydro-4H-pyrrolo[2,3-b]quinolin-4-one
DB07662 N-[4-(3-BROMO-PHENYLAMINO)-QUINAZOLIN-6-YL]-ACRYLAMIDE
DB07714 6-(3-METHYL-1,4-DIOXO-1,4-DIHYDRONAPHTHALEN-2-YL)HEXANOIC ACID
DB07782 4-AMINO-2-TRIFLUOROMETHYL-5-HYDROXYMETHYLPYRIMIDINE PYROPHOSPHATE
DB07945 5-(3-carbamoylbenzyl)-5,6,7,8,9,10-hexahydrocyclohepta[b]indole-4-carboxylic acid
DB07966 [4-({4-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl}amino)phenyl]acetonitrile
DB08052 1-cyclopentyl-3-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
DB08053 1-cyclobutyl-3-(3,4-dimethoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
DB08054 1-(1-methylethyl)-3-quinolin-6-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
DB08192 2-(4-CARCOXY-5-ISOPROPYLTHIAZOLYL)BENZOPIPERIDINE
DB08276 N-METHYL O-NITROPHENYL AMINOETHYLDIPHOSPHATE BERYLLIUM TRIFLUORIDE
DB08427 PREPHENIC ACID
DB08462 N-(4-PHENYLAMINO-QUINAZOLIN-6-YL)-ACRYLAMIDE
DB08564 (2E)-N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(dimethylamino)but-2-enamide
DB08607 (5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE
DB08648 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID
DB08901 Ponatinib
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