DT-Web

DB03755 - Adenosine-5'-[Beta, Gamma-Methylene]Tetraphosphate


Identification
Name Adenosine-5'-[Beta, Gamma-Methylene]Tetraphosphate
Accession Number DB03755 (EXPT00417)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 585.1881
Groups experimental
Monoisotopic Weight 584.982811011
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Folylpolyglutamate synthase
Name Folylpolyglutamate synthase
Gene Name fgs
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.6074

Predictions


Id Partner name Gene Name Score
24 Thymidylate synthase TMP1 0.0844
359 Thymidylate synthase TYMS 0.0844
2626 Thymidylate synthase thyA 0.0844
2729 Thymidylate synthase thyA 0.0844
5352 Thymidylate synthase THYA 0.0844
2621 Thermoresistant gluconokinase gntK 0.0315
5466 Putative sugar kinase STM4066 0.0315
4517 Probable butyrate kinase 2 buk2 0.0315
2878 Probable serine/threonine-protein kinase pknB pknB 0.0315
2299 UDP-N-acetylmuramate--L-alanine ligase murC 0.029
5312 Kinesin-like protein KIF1A KIF1A 0.029
3669 Ribokinase rbsK 0.0274
2615 Chemotaxis protein cheA cheA 0.0274
6390 Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 ATP2A1 0.0262
2383 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0261
2937 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0261
4620 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0261
6594 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0261
6609 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0261
6646 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.0261
2757 Inorganic pyrophosphatase ppa 0.0261
6238 Inorganic pyrophosphatase ppa 0.0261
6968 Inorganic pyrophosphatase PPA1 0.0261
2817 Phosphoribosylglycinamide formyltransferase 2 purT 0.0253
3168 Beta-lactamase OXA-1 bla 0.0247
4819 Hydrolase Not Available 0.0247
5249 Hydrolase Not Available 0.0247
5436 Hydrolase Not Available 0.0247
3230 Non-ATP-dependent L-selective hydantoinase lhyD 0.0247
3122 D-hydantoinase Not Available 0.0247
3145 D-hydantoinase hyuA 0.0247
4553 Bifunctional adenosylcobalamin biosynthesis protein cobU cobU 0.0228
2755 Hypoxanthine-guanine-xanthine phosphoribosyltransferase LACZ 0.0227
2647 RNA-directed RNA polymerase P2 0.0227
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0227
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0227
36 Insulin receptor INSR 0.0224
48 Pyridoxal kinase PDXK 0.022
3292 Alanine racemase, catabolic dadX 0.0215
3281 Isoaspartyl dipeptidase iadA 0.0215
3237 Beta-lactamase OXA-2 bla 0.0215
4264 Alpha-L-fucosidase, putative TM_0306 0.0215
2149 Angiogenin ANG 0.021
3010 Regulatory protein blaR1 blaR1 0.021
2801 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase murE 0.0199
2983 Methylmalonyl-CoA carboxyltransferase 5S subunit Not Available 0.0198
2885 Carboxyethyl-arginine beta-lactam-synthase bls 0.0198
4600 Malonamidase E2 Not Available 0.0198
2434 NH(3)-dependent NAD(+) synthetase nadE 0.0198
2910 NH(3)-dependent NAD(+) synthetase nadE 0.0198
3217 NH(3)-dependent NAD(+) synthetase nadE 0.0198
2727 S-adenosylmethionine synthetase metK 0.0189
2646 Dihydroorotase pyrC 0.0187
4549 Endonuclease III HP_0602 0.0187
2428 Thiamine-phosphate pyrophosphorylase thiE 0.0177
2340 Beta-lactamase PSE-2 bla 0.0169
6395 Myosin-14 MYH14 0.0168
2796 Parathion hydrolase opd 0.0168
6539 Parathion hydrolase opd 0.0168
894 Alanine racemase alr 0.0163
2453 Alanine racemase alr 0.0163
2317 UDP-N-acetylmuramoylalanine--D-glutamate ligase murD 0.0159
87 Hypoxanthine-guanine phosphoribosyltransferase HPRT1 0.0141
5294 Nucleoside diphosphate kinase A NME1 0.014
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.012
2240 Cell division protein kinase 2 CDK2 0.0093
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