DT-Web

DB03310 - Oxidized Glutathione Disulfide


Identification
Name Oxidized Glutathione Disulfide
Accession Number DB03310 (EXPT01575)
Type small molecule
Description A GLUTATHIONE dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 612.631
Groups experimental
Monoisotopic Weight 612.151961898
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Glutathione S-transferase Mu 2
Name Glutathione S-transferase Mu 2
Gene Name GSTM2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0405
Glutathione reductase, mitochondrial
Name Glutathione reductase, mitochondrial
Gene Name GSR
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0873

Predictions


Id Partner name Gene Name Score
896 Glutathione S-transferase Mu 1 GSTM1 0.1626
4200 Cytochrome P450 1A2 CYP1A2 0.0247
4035 Glutathione S-transferase Mu 5 GSTM5 0.0158
4602 Osmotically inducible protein C tthHB8IM 0.0149
2664 S-ribosylhomocysteine lyase luxS 0.0149
2725 S-ribosylhomocysteine lyase luxS 0.0149
2670 Pyridoxamine kinase pdxY 0.0149
900 Glutathione S-transferase A4 GSTA4 0.0146
4043 Glutaredoxin-2, mitochondrial GLRX2 0.0146
903 Glutathione S-transferase A5 GSTA5 0.0146
4040 Glutathione peroxidase 7 GPX7 0.0146
4034 Glutaredoxin-1 GLRX 0.0146
1928 Leukotriene C4 synthase LTC4S 0.0146
911 Glutathione peroxidase 3 GPX3 0.0146
4037 Hypothetical protein GPX1 0.0146
4297 Hypothetical protein SP_1951 0.0146
4521 Hypothetical protein BC_2969 0.0146
4540 Hypothetical protein TM_1070 0.0146
4555 Hypothetical protein MT1739 0.0146
4569 Hypothetical protein mshD 0.0146
4578 Hypothetical protein PA3270 0.0146
4747 Hypothetical protein PA3967 0.0146
5177 Hypothetical protein TM_0096 0.0146
5194 Hypothetical protein PA1204 0.0146
5240 Hypothetical protein Rv2991 0.0146
5370 Hypothetical protein TM_1158 0.0146
5710 Hypothetical protein Tb927.5.1360 0.0146
4036 Glutathione peroxidase 6 GPX6 0.0146
4039 CDNA FLJ23636 fis, clone CAS07176 GPX8 0.0146
4029 Microsomal glutathione S-transferase 3 MGST3 0.0146
4032 Microsomal glutathione S-transferase 1 MGST1 0.0146
910 Epididymal secretory glutathione peroxidase GPX5 0.0146
4030 Thioredoxin domain-containing protein 12 TXNDC12 0.0146
907 Glutathione peroxidase 2 GPX2 0.0146
906 Glutathione peroxidase 1 GPX1 0.0146
4038 Glutathione peroxidase 4 GPX4 0.0146
1975 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial GPX4 0.0146
4042 Glutathione transferase omega-2 GSTO2 0.0146
4033 S-formylglutathione hydrolase ESD 0.0146
1056 Gamma-glutamyltranspeptidase 1 GGT1 0.0146
897 Glutathione S-transferase kappa 1 GSTK1 0.0137
898 Glutathione S-transferase A3 GSTA3 0.0135
3319 Hydroxyacylglutathione hydrolase HAGH 0.0135
909 Maleylacetoacetate isomerase GSTZ1 0.0131
3599 Peroxiredoxin-2 PRDX2 0.013
4601 HMG-CoA synthase mvaS 0.013
2688 Peptide deformylase def 0.013
2708 Peptide deformylase def 0.013
3004 Peptide deformylase def 0.013
4337 Peptide deformylase def 0.013
4338 Peptide deformylase def 0.013
5368 Peptide deformylase def 0.013
5371 Peptide deformylase def 0.013
6375 Peptide deformylase def 0.013
6378 Peptide deformylase def 0.013
6379 Peptide deformylase def 0.013
6776 Peptide deformylase def 0.013
6900 Peptide deformylase def 0.013
2378 Carboxymethylenebutenolidase clcD 0.013
2705 Dimethyl sulfoxide reductase dmsA 0.0129
901 Glutathione S-transferase Mu 4 GSTM4 0.0122
2714 Chorismate mutase aroH 0.012
4611 Chorismate mutase aroG 0.012
2603 Beta-lactamase II blm 0.0119
899 Glutathione S-transferase Mu 3 GSTM3 0.0115
4600 Malonamidase E2 Not Available 0.0113
905 Glutathione transferase omega-1 GSTO1 0.011
4041 Microsomal glutathione S-transferase 2 MGST2 0.011
207 Glutathione synthetase GSS 0.0101
5269 Glutathione synthetase gshB 0.0101
1313 Lactoylglutathione lyase GLO1 0.0101
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0096
4031 Glutathione S-transferase A1 GSTA1 0.0096
2183 Fatty acid-binding protein, adipocyte FABP4 0.0089
908 Glutathione S-transferase theta-1 GSTT1 0.0082
3932 Glutathione S-transferase A2 GSTA2 0.0077
904 Glutathione S-transferase P GSTP1 0.0076
6136 Multidrug resistance-associated protein 5 ABCC5 0.0065
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0059
2164 Multidrug resistance-associated protein 4 ABCC4 0.0055
862 Multidrug resistance-associated protein 1 ABCC1 0.0053
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0048
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.004
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.004
4477 Dihydrolipoyl dehydrogenase lpdV 0.0035
5077 Dihydrolipoyl dehydrogenase Not Available 0.0035
5117 Dihydrolipoyl dehydrogenase lpd 0.0035
4486 Phenol 2-hydroxylase component B pheA2 0.0035
4439 Ferredoxin reductase bphA4 0.0035
4440 NADH peroxidase npr 0.0032
327 Glutathione reductase gor 0.0029
5110 Glutathione reductase GR2 0.0029
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0028
5122 Mersacidin decarboxylase mrsD 0.0024
526 Thioredoxin reductase trxB 0.0024
3767 Thioredoxin reductase trxB 0.0024
3133 UDP-galactopyranose mutase glf 0.0024
5099 UDP-galactopyranose mutase glf 0.0024
5095 Putidaredoxin reductase camA 0.0024
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0024
3763 5,10-methylenetetrahydrofolate reductase metF 0.0024
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0024
5094 5,10-methylenetetrahydrofolate reductase metF 0.0024
5078 Amine oxidase, flavin-containing PSPTO1126 0.0024
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0024
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0024
5109 Outer membrane protein p64k or PM-6 m-6 0.0024
5115 FkbI fkbI 0.0024
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0024
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0024
5083 Cryptochrome DASH cry 0.0024
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0024
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0024
5081 L-aspartate oxidase nadB 0.0024
5111 Phenylacetone monooxygenase pamO 0.0024
1410 Oxidoreductase HSD17B6 0.0024
4725 Oxidoreductase Not Available 0.0024
5124 Oxidoreductase Not Available 0.0024
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0024
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0022
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0022
816 Biliverdin reductase A BLVRA 0.0022
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0022
5073 Ferredoxin--NADP reductase petH 0.0021
5076 Ferredoxin--NADP reductase fpr 0.0021
5119 Ferredoxin--NADP reductase petH 0.0021
5121 Ferredoxin--NADP reductase fpr 0.0021
2526 NADPH-ferredoxin reductase fprA fprA 0.0021
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0021
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0021
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0021
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0021
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0021
5072 N,N-dimethylglycine oxidase dmg 0.0021
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0021
2470 Pyruvate oxidase pox5 0.0021
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0021
3594 Deoxyribodipyrimidine photo-lyase phr 0.0021
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0021
5080 Deoxyribodipyrimidine photo-lyase phr 0.0021
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0021
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0021
2268 Cholesterol oxidase choB 0.0021
2822 Cholesterol oxidase choA 0.0021
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0021
646 Malate dehydrogenase, cytoplasmic MDH1 0.0021
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0021
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0021
597 Dihydropteridine reductase QDPR 0.0021
328 Sorbitol dehydrogenase SORD 0.0021
396 Alcohol dehydrogenase 4 ADH4 0.0021
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0021
3102 Flavohemoprotein hmp 0.002
4969 Flavohemoprotein hmp 0.002
12 Alcohol dehydrogenase class 3 ADH5 0.002
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.002
77 L-lactate dehydrogenase B chain LDHB 0.002
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.002
2893 Glycine oxidase thiO 0.002
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0019
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0019
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0019
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0019
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0019
473 L-lactate dehydrogenase A chain LDHA 0.0019
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0019
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0019
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0018
2823 Trypanothione reductase TPR 0.0018
2567 Thymidylate synthase thyX thyX 0.0018
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0018
126 D-lactate dehydrogenase dld 0.0018
3545 D-lactate dehydrogenase Not Available 0.0018
4510 D-lactate dehydrogenase ldhA 0.0018
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0018
605 Fumarate reductase flavoprotein subunit frdA 0.0018
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0018
3673 Fumarate reductase flavoprotein subunit fccA 0.0018
4912 Fumarate reductase flavoprotein subunit ifcA 0.0018
6549 Fumarate reductase flavoprotein subunit frdA 0.0018
2769 P-hydroxybenzoate hydroxylase pobA 0.0018
2809 P-hydroxybenzoate hydroxylase pobA 0.0018
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0017
2380 Monomeric sarcosine oxidase soxA 0.0017
569 Retinal dehydrogenase 2 ALDH1A2 0.0017
611 Retinal dehydrogenase 1 ALDH1A1 0.0017
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0017
251 Alcohol dehydrogenase 1A ADH1A 0.0016
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0016
6645 D-amino-acid oxidase DAO 0.0016
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0016
3947 Xanthine dehydrogenase/oxidase XDH 0.0016
444 Alcohol dehydrogenase 1B ADH1B 0.0016
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.0015
4423 Levodione reductase lvr 0.0015
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.0015
4428 Redox-sensing transcriptional repressor rex rex 0.0015
4449 ADP-ribosyltransferase Not Available 0.0015
4471 CDP-D-glucose-4,6-dehydratase ascB 0.0015
4455 Glycerol dehydrogenase gldA 0.0015
4435 L-aspartate dehydrogenase nadX 0.0015
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.0015
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.0015
4472 Glucose 1-dehydrogenase Not Available 0.0015
4487 Transcriptional regulator nadR nadR 0.0015
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.0015
4443 Quinate/shikimate dehydrogenase ydiB 0.0015
4500 L-lactate dehydrogenase 2 ldh2 0.0015
4447 Hypothetical protein yhfP yhfP 0.0015
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.0015
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.0015
3381 Alcohol dehydrogenase Not Available 0.0015
4508 Alcohol dehydrogenase adhA 0.0015
4414 Dehydrogenase TT_P0035 0.0015
2350 3-isopropylmalate dehydrogenase leuB 0.0015
3092 3-isopropylmalate dehydrogenase leuB 0.0015
4418 AGR_L_3209p AGR_L_3209 0.0015
4507 Alanine dehydrogenase ald 0.0015
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.0015
4497 Benzyl alcohol dehydrogenase xylB 0.0015
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.0015
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.0015
4502 Formate dehydrogenase Not Available 0.0015
3729 Citrate synthase gltA 0.0015
4575 Citrate synthase cit 0.0015
4580 Citrate synthase gltA 0.0015
4451 Vip2Ac vip2Ac 0.0015
4467 Alpha-glucosidase, putative TM_0752 0.0015
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.0015
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0015
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0014
517 Alcohol dehydrogenase 1C ADH1C 0.0014
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0013
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.0013
4427 TDP-glucose-4,6-dehydratase desIV 0.0013
3177 dTDP-glucose 4,6-dehydratase rfbB 0.0013
4499 dTDP-glucose 4,6-dehydratase rmlB 0.0013
4503 NADPH-flavin oxidoreductase frp 0.0013
4482 UDP-galactose 4-epimerase galE 0.0013
2967 CDP-paratose 2-epimerase rfbE 0.0013
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0013
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0013
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0013
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.0013
2424 L-lactate dehydrogenase ldh 0.0013
2641 L-lactate dehydrogenase Not Available 0.0013
4437 L-lactate dehydrogenase ldh 0.0013
4442 L-lactate dehydrogenase ldh 0.0013
3401 D-2-hydroxyisocaproate dehydrogenase Not Available 0.0013
2538 6-phospho-beta-glucosidase bglT bglT 0.0013
2336 2,3-diketo-L-gulonate reductase dlgD 0.0013
2507 Diphtheria toxin Not Available 0.0013
3081 3-dehydroquinate synthase aroB 0.0013
3615 Dihydrodipicolinate reductase dapB 0.0013
3618 Dihydrodipicolinate reductase dapB 0.0013
4462 Dihydrodipicolinate reductase dapB 0.0013
2393 Maltose-6'-phosphate glucosidase glvA 0.0013
4509 Acetoin(diacetyl) reductase budC 0.0013
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.0013
2591 Urocanate hydratase hutU 0.0013
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.0013
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.0013
2018 Deoxyhypusine synthase DHPS 0.0013
4496 C-terminal-binding protein 1 CTBP1 0.0013
4498 Ornithine cyclodeaminase PP3533 0.0013
4450 Iota toxin component Ia Not Available 0.0013
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.0013
76 Nitric-oxide synthase, brain NOS1 0.0012
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0012
4120 NADPH--cytochrome P450 reductase POR 0.0012
2683 Mono-ADP-ribosyltransferase C3 C3 0.0012
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.0011
4504 WbpP Not Available 0.0011
4318 Siroheme synthase cysG 0.0011
3367 GDP-mannose 6-dehydrogenase algD 0.0011
4343 Alpha-glucosidase aglA 0.0011
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.0011
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0011
63 Malate dehydrogenase mdh 0.0011
2329 Malate dehydrogenase mdh 0.0011
3445 Malate dehydrogenase mdh 0.0011
4420 Malate dehydrogenase mdh 0.0011
4438 Malate dehydrogenase mdh 0.0011
2617 Nitric oxide synthase oxygenase nos 0.0011
2701 Nitric oxide synthase oxygenase nos 0.0011
4476 Mannitol dehydrogenase mtlD 0.0011
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0011
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0011
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.0011
2434 NH(3)-dependent NAD(+) synthetase nadE 0.0011
2910 NH(3)-dependent NAD(+) synthetase nadE 0.0011
3217 NH(3)-dependent NAD(+) synthetase nadE 0.0011
2826 Glucose--fructose oxidoreductase gfo 0.0011
3070 Adenosylhomocysteinase AHCY 0.0011
4424 Adenosylhomocysteinase PFE1050w 0.0011
6278 Adenosylhomocysteinase ahcY 0.0011
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0011
3191 Histidinol dehydrogenase hisD 0.0011
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.001
3939 Amine oxidase [flavin-containing] B MAOB 0.001
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.001
666 NADP-dependent malic enzyme ME1 0.001
857 Malate dehydrogenase, mitochondrial MDH2 0.001
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.001
602 Acyl carrier protein, mitochondrial NDUFAB1 0.001
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.001
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.001
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.001
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.001
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.001
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.001
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.001
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.001
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.001
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.001
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.001
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.001
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.001
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.001
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.001
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.001
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.001
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.001
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.001
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.001
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.001
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.001
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.001
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.001
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.001
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.001
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.001
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.001
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.001
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.001
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.001
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.001
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.001
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.001
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.001
107 C-4 methylsterol oxidase SC4MOL 0.001
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.001
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.001
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.001
662 Fatty aldehyde dehydrogenase ALDH3A2 0.001
729 GDP-L-fucose synthetase TSTA3 0.001
3463 GDP-L-fucose synthetase fcl 0.001
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.001
167 L-lactate dehydrogenase C chain LDHC 0.001
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.001
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.001
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.001
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.001
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.001
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.001
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.001
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.001
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.001
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.001
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.001
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.001
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.001
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.001
644 Heme oxygenase 2 HMOX2 0.001
4982 Heme oxygenase 2 pbsA2 0.001
206 3-keto-steroid reductase HSD17B7 0.001
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.001
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.001
34 7-dehydrocholesterol reductase DHCR7 0.001
711 UDP-glucose 6-dehydrogenase UGDH 0.001
3672 UDP-glucose 6-dehydrogenase hasB 0.001
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.001
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.001
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.001
3726 D-3-phosphoglycerate dehydrogenase serA 0.001
4291 D-3-phosphoglycerate dehydrogenase serA 0.001
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.001
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.001
643 Peroxisomal bifunctional enzyme EHHADH 0.001
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.001
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.001
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.001
11 NAD(P) transhydrogenase, mitochondrial NNT 0.001
2286 Isocitrate dehydrogenase [NADP] icd 0.001
2302 Isocitrate dehydrogenase [NADP] icd 0.001
2771 Isocitrate dehydrogenase [NADP] icd 0.001
4491 DNA ligase, NAD-dependent ligA 0.001
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.001
3941 Amine oxidase [flavin-containing] A MAOA 0.0009
2762 UDP-glucose 4-epimerase GALE 0.0009
3461 UDP-glucose 4-epimerase galE 0.0009
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0009
13 Aminomethyltransferase, mitochondrial AMT 0.0009
626 Cysteine dioxygenase type 1 CDO1 0.0009
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0009
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0009
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0009
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0009
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0009
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0009
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0009
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0008
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0008
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0008
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0008
6026 Alcohol dehydrogenase 6 ADH6 0.0008
627 11-cis retinol dehydrogenase RDH5 0.0008
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0008
654 Flavin reductase BLVRB 0.0008
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0008
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0008
810 Heme oxygenase 1 HMOX1 0.0008
3391 Heme oxygenase 1 pbsA1 0.0008
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0008
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0008
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0008
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0008
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.0008
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0008
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0007
279 Tyrosinase TYR 0.0007
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0007
380 Cytochrome P450 17A1 CYP17A1 0.0007
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0007
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0007
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0007
822 Aldose reductase AKR1B1 0.0007
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0006
365 Dihydrofolate reductase DHFR 0.0006
2381 Dihydrofolate reductase DFR1 0.0006
2833 Dihydrofolate reductase Not Available 0.0006
2931 Dihydrofolate reductase folA 0.0006
3544 Dihydrofolate reductase folA 0.0006
3682 Dihydrofolate reductase folA 0.0006
6642 Dihydrofolate reductase folA 0.0006
6756 Dihydrofolate reductase dfrA 0.0006
468 Cytochrome P450 4A11 CYP4A11 0.0006
6020 Aldehyde oxidase AOX1 0.0006
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