DT-Web

DB02885 - 4-Imino-5-Methidyl-2-Trifluoromethylpyrimidine


Identification
Name 4-Imino-5-Methidyl-2-Trifluoromethylpyrimidine
Accession Number DB02885 (EXPT01848)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 175.1113
Groups experimental
Monoisotopic Weight 175.035731758
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Thiamine-phosphate pyrophosphorylase
Name Thiamine-phosphate pyrophosphorylase
Gene Name thiE
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.7302

Predictions


Id Partner name Gene Name Score
2383 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.02
2937 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.02
4620 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.02
6594 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.02
6609 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.02
6646 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase ispF 0.02
2757 Inorganic pyrophosphatase ppa 0.02
6238 Inorganic pyrophosphatase ppa 0.02
6968 Inorganic pyrophosphatase PPA1 0.02
2755 Hypoxanthine-guanine-xanthine phosphoribosyltransferase LACZ 0.0174
4553 Bifunctional adenosylcobalamin biosynthesis protein cobU cobU 0.0174
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0174
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0174
2647 RNA-directed RNA polymerase P2 0.0174
2149 Angiogenin ANG 0.016
3010 Regulatory protein blaR1 blaR1 0.016
2434 NH(3)-dependent NAD(+) synthetase nadE 0.0151
2910 NH(3)-dependent NAD(+) synthetase nadE 0.0151
3217 NH(3)-dependent NAD(+) synthetase nadE 0.0151
2885 Carboxyethyl-arginine beta-lactam-synthase bls 0.0151
4600 Malonamidase E2 Not Available 0.0151
2717 Folylpolyglutamate synthase fgs 0.0145
2727 S-adenosylmethionine synthetase metK 0.0145
6395 Myosin-14 MYH14 0.0128
87 Hypoxanthine-guanine phosphoribosyltransferase HPRT1 0.0107
5294 Nucleoside diphosphate kinase A NME1 0.0107
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0091
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