DT-Web

DB04242 - P-Hydroxybenzoic Acid


Identification
Name P-Hydroxybenzoic Acid
Accession Number DB04242 (EXPT02580)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 138.1207
Groups experimental
Monoisotopic Weight 138.031694058
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


FcbC1 protein
Name FcbC1 protein
Gene Name fcbC
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.0011
P-hydroxybenzoate hydroxylase
Name P-hydroxybenzoate hydroxylase
Gene Name pobA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.3284
Chorismate--pyruvate lyase
Name Chorismate--pyruvate lyase
Gene Name ubiC
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.5772
P-hydroxybenzoate hydroxylase
Name P-hydroxybenzoate hydroxylase
Gene Name pobA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.3284

Predictions


Id Partner name Gene Name Score
4280 4-hydroxybenzoyl-CoA thioesterase Not Available 0.4264
4593 ADP compounds hydrolase nudE nudE 0.047
2460 ADP-ribose pyrophosphatase nudF 0.0409
4349 ADP-ribose pyrophosphatase ndx4 0.0409
3108 CDP-glucose 4,6-dehydratase rfbG 0.0409
3725 Lactaldehyde reductase fucO 0.0409
4037 Hypothetical protein GPX1 0.0378
4297 Hypothetical protein SP_1951 0.0378
4521 Hypothetical protein BC_2969 0.0378
4540 Hypothetical protein TM_1070 0.0378
4555 Hypothetical protein MT1739 0.0378
4569 Hypothetical protein mshD 0.0378
4578 Hypothetical protein PA3270 0.0378
4747 Hypothetical protein PA3967 0.0378
5177 Hypothetical protein TM_0096 0.0378
5194 Hypothetical protein PA1204 0.0378
5240 Hypothetical protein Rv2991 0.0378
5370 Hypothetical protein TM_1158 0.0378
5710 Hypothetical protein Tb927.5.1360 0.0378
6790 Elongation factor 2 EEF2 0.0356
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0341
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.032
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.032
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.032
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.032
4567 Putative acyl-CoA thioester hydrolase HI0827 HI_0827 0.0137
4579 Serine acetyltransferase cysE 0.0137
6807 Serine acetyltransferase cysE 0.0137
4564 YvbK protein yvbK 0.0137
4566 Acyl-CoA hydrolase BC_2038 0.0137
4572 Acyl-CoA hydrolase BH0798 0.0137
4576 Aac(6')-Ii protein aac(6')-Ii 0.0137
4577 4'-phosphopantetheinyl transferase sfp sfp 0.0137
2528 Fatty acid metabolism regulator protein fadR 0.0137
6740 Fatty acid metabolism regulator protein fadR 0.0137
4565 Aminoglycoside 6'-N-acetyltransferase aac(6')-Iy 0.012
3317 Holo-[acyl-carrier-protein] synthase acpS 0.012
4381 Holo-[acyl-carrier-protein] synthase acpS 0.012
3729 Citrate synthase gltA 0.012
4575 Citrate synthase cit 0.012
4580 Citrate synthase gltA 0.012
3125 Protease synthase and sporulation negative regulatory protein PAI 1 paiA 0.0119
4574 PROBABLE NAPHTHOATE SYNTHASE MENB menB 0.0119
3560 Gentamicin 3'-acetyltransferase aacC1 0.0119
4563 Acetyl transferase rimL 0.0119
2409 Acetyl-CoA acetyltransferase, cytosolic ACAT2 0.0119
2396 Formyl-coenzyme A transferase frc 0.0119
3457 Formyl-coenzyme A transferase frc 0.0119
3024 Crotonobetainyl-CoA:carnitine CoA-transferase caiB 0.0119
3489 Acetyl-coenzyme A synthetase acs 0.0119
5095 Putidaredoxin reductase camA 0.0118
5122 Mersacidin decarboxylase mrsD 0.0118
3763 5,10-methylenetetrahydrofolate reductase metF 0.0118
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0118
5094 5,10-methylenetetrahydrofolate reductase metF 0.0118
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0118
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0118
526 Thioredoxin reductase trxB 0.0118
3767 Thioredoxin reductase trxB 0.0118
5078 Amine oxidase, flavin-containing PSPTO1126 0.0118
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0118
5115 FkbI fkbI 0.0117
5109 Outer membrane protein p64k or PM-6 m-6 0.0117
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0117
5111 Phenylacetone monooxygenase pamO 0.0117
5083 Cryptochrome DASH cry 0.0117
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0117
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0117
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0117
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0117
5081 L-aspartate oxidase nadB 0.0117
1410 Oxidoreductase HSD17B6 0.0117
4725 Oxidoreductase Not Available 0.0117
5124 Oxidoreductase Not Available 0.0117
3133 UDP-galactopyranose mutase glf 0.0117
5099 UDP-galactopyranose mutase glf 0.0117
3199 Phosphopantetheine adenylyltransferase coaD 0.011
3543 Phosphopantetheine adenylyltransferase coaD 0.011
3567 Phosphopantetheine adenylyltransferase coaD 0.011
5289 Phosphopantetheine adenylyltransferase coaD 0.011
2560 Galactoside O-acetyltransferase lacA 0.011
2285 Streptogramin A acetyltransferase vatD 0.011
3697 Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase glmU 0.011
3178 Formate acetyltransferase 1 pflB 0.011
2377 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Not Available 0.011
2248 Malate synthase G glcB 0.011
3190 Malate synthase G glcB 0.011
4573 Histone acetyltransferase PCAF KAT2B 0.011
2371 Pantothenate kinase coaA 0.0104
4486 Phenol 2-hydroxylase component B pheA2 0.0102
3594 Deoxyribodipyrimidine photo-lyase phr 0.0102
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0102
5080 Deoxyribodipyrimidine photo-lyase phr 0.0102
2526 NADPH-ferredoxin reductase fprA fprA 0.0102
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0102
4439 Ferredoxin reductase bphA4 0.0102
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0102
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0102
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0102
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0102
5073 Ferredoxin--NADP reductase petH 0.0102
5076 Ferredoxin--NADP reductase fpr 0.0102
5119 Ferredoxin--NADP reductase petH 0.0102
5121 Ferredoxin--NADP reductase fpr 0.0102
4477 Dihydrolipoyl dehydrogenase lpdV 0.0102
5077 Dihydrolipoyl dehydrogenase Not Available 0.0102
5117 Dihydrolipoyl dehydrogenase lpd 0.0102
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0102
5072 N,N-dimethylglycine oxidase dmg 0.0102
2268 Cholesterol oxidase choB 0.0102
2822 Cholesterol oxidase choA 0.0102
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0102
2470 Pyruvate oxidase pox5 0.0102
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0102
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0102
2376 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase dapD 0.0099
551 Carnitine O-acetyltransferase CRAT 0.0096
2893 Glycine oxidase thiO 0.0094
3102 Flavohemoprotein hmp 0.0094
4969 Flavohemoprotein hmp 0.0094
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0094
4440 NADH peroxidase npr 0.0094
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0094
2596 Acetyl-CoA acetyltransferase phbA 0.009
615 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.009
3138 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.009
4568 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.009
6370 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 0.009
2567 Thymidylate synthase thyX thyX 0.0089
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0089
2823 Trypanothione reductase TPR 0.0089
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0085
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0085
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0085
126 D-lactate dehydrogenase dld 0.0084
3545 D-lactate dehydrogenase Not Available 0.0084
4510 D-lactate dehydrogenase ldhA 0.0084
4388 Aminoglycoside 2'-N-acetyltransferase aac 0.0084
327 Glutathione reductase gor 0.0083
5110 Glutathione reductase GR2 0.0083
2380 Monomeric sarcosine oxidase soxA 0.0082
605 Fumarate reductase flavoprotein subunit frdA 0.0082
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0082
3673 Fumarate reductase flavoprotein subunit fccA 0.0082
4912 Fumarate reductase flavoprotein subunit ifcA 0.0082
6549 Fumarate reductase flavoprotein subunit frdA 0.0082
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0078
6645 D-amino-acid oxidase DAO 0.0078
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.007
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0064
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0064
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0063
714 Glutathione reductase, mitochondrial GSR 0.0063
76 Nitric-oxide synthase, brain NOS1 0.0059
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0056
4120 NADPH--cytochrome P450 reductase POR 0.0053
3939 Amine oxidase [flavin-containing] B MAOB 0.0047
3947 Xanthine dehydrogenase/oxidase XDH 0.0045
3941 Amine oxidase [flavin-containing] A MAOA 0.0043
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