DT-Web

DB03343 - Malate Like Intermediate


Identification
Name Malate Like Intermediate
Accession Number DB03343 (EXPT03039)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 132.0716
Groups experimental
Monoisotopic Weight 132.005873238
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Fumarate reductase flavoprotein subunit
Name Fumarate reductase flavoprotein subunit
Gene Name fccA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.0913

Predictions


Id Partner name Gene Name Score
63 Malate dehydrogenase mdh 0.1023
2329 Malate dehydrogenase mdh 0.1023
3445 Malate dehydrogenase mdh 0.1023
4420 Malate dehydrogenase mdh 0.1023
4438 Malate dehydrogenase mdh 0.1023
605 Fumarate reductase flavoprotein subunit frdA 0.0913
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0913
4912 Fumarate reductase flavoprotein subunit ifcA 0.0913
6549 Fumarate reductase flavoprotein subunit frdA 0.0913
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0781
3102 Flavohemoprotein hmp 0.008
4969 Flavohemoprotein hmp 0.008
526 Thioredoxin reductase trxB 0.0059
3767 Thioredoxin reductase trxB 0.0059
5115 FkbI fkbI 0.0059
3133 UDP-galactopyranose mutase glf 0.0059
5099 UDP-galactopyranose mutase glf 0.0059
5095 Putidaredoxin reductase camA 0.0059
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0059
5081 L-aspartate oxidase nadB 0.0059
3763 5,10-methylenetetrahydrofolate reductase metF 0.0059
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0059
5094 5,10-methylenetetrahydrofolate reductase metF 0.0059
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0059
5078 Amine oxidase, flavin-containing PSPTO1126 0.0059
5122 Mersacidin decarboxylase mrsD 0.0059
5111 Phenylacetone monooxygenase pamO 0.0059
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0059
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0059
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0059
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0059
5083 Cryptochrome DASH cry 0.0059
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0059
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0059
1410 Oxidoreductase HSD17B6 0.0059
4725 Oxidoreductase Not Available 0.0059
5124 Oxidoreductase Not Available 0.0059
5109 Outer membrane protein p64k or PM-6 m-6 0.0059
4486 Phenol 2-hydroxylase component B pheA2 0.0051
5073 Ferredoxin--NADP reductase petH 0.0051
5076 Ferredoxin--NADP reductase fpr 0.0051
5119 Ferredoxin--NADP reductase petH 0.0051
5121 Ferredoxin--NADP reductase fpr 0.0051
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0051
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0051
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0051
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0051
2470 Pyruvate oxidase pox5 0.0051
3594 Deoxyribodipyrimidine photo-lyase phr 0.0051
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0051
5080 Deoxyribodipyrimidine photo-lyase phr 0.0051
4477 Dihydrolipoyl dehydrogenase lpdV 0.0051
5077 Dihydrolipoyl dehydrogenase Not Available 0.0051
5117 Dihydrolipoyl dehydrogenase lpd 0.0051
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0051
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0051
4439 Ferredoxin reductase bphA4 0.0051
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0051
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0051
2526 NADPH-ferredoxin reductase fprA fprA 0.0051
2268 Cholesterol oxidase choB 0.0051
2822 Cholesterol oxidase choA 0.0051
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0051
5072 N,N-dimethylglycine oxidase dmg 0.0051
76 Nitric-oxide synthase, brain NOS1 0.0051
4440 NADH peroxidase npr 0.0047
2893 Glycine oxidase thiO 0.0047
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0047
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0047
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0045
2567 Thymidylate synthase thyX thyX 0.0045
2823 Trypanothione reductase TPR 0.0044
126 D-lactate dehydrogenase dld 0.0043
3545 D-lactate dehydrogenase Not Available 0.0043
4510 D-lactate dehydrogenase ldhA 0.0043
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0043
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0043
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0043
2769 P-hydroxybenzoate hydroxylase pobA 0.0043
2809 P-hydroxybenzoate hydroxylase pobA 0.0043
327 Glutathione reductase gor 0.0042
5110 Glutathione reductase GR2 0.0042
2380 Monomeric sarcosine oxidase soxA 0.0041
4954 Soluble cytochrome b558 Not Available 0.0041
4943 Cytochrome c6 petJ 0.0041
4934 Cytochrome c-551 nirM 0.0041
5218 Cytochrome c-551 nirM 0.0041
4961 Hemophore HasA hasA 0.0041
4915 Cytochrome c-550 psbV 0.0041
4959 Cytochrome c-550 psbV 0.0041
5216 Cytochrome c-550 psbV 0.0041
4998 Hemoglobin-like protein yjbI yjbI 0.0041
4975 Cytochrome c-556 RPA3973 0.0041
4935 Cytochrome c-554 cycA1 0.0041
4984 Neuroglobin NGB 0.0041
3116 Bacterioferritin bfr 0.0041
4906 Bacterioferritin bfr 0.0041
4965 Bacterioferritin bfr 0.0041
4925 Cytochrome c-type protein SHP shp 0.0041
4905 Cytochrome c2 Not Available 0.0041
4939 Cytochrome c2 cycA 0.0041
4964 Cytochrome c2 cycA 0.0041
4979 Cytochrome c2 cycA 0.0041
6673 Cytochrome c2 cycA 0.0041
4910 Cytoglobin CYGB 0.0041
4907 Cytochrome c-L moxG 0.0041
6865 Cytochrome c-L moxG 0.0041
4981 Iron-starvation protein PigA pigA 0.0041
4971 Nonaheme cytochrome c hmcA 0.0041
4936 Cytochrome c2 iso-2 Not Available 0.0041
4916 Cyanoglobin glbN 0.0041
4909 CooA protein cooA 0.0041
4994 Hemoglobin-like protein HbO glbO 0.0041
5000 HemO hemO 0.0041
4937 Cytochrome oxidase subunit II rcoxA 0.0041
4999 Cytochrome P450 165B3 CYP165B3 0.0041
4947 Bacterial hemoglobin vhb 0.0041
4942 Diheme cytochrome c napB napB 0.0041
4922 Cytochrome c, putative SO_4144 0.0041
4989 Cytochrome c551 peroxidase ccp 0.0041
5222 Cytochrome c551 peroxidase ccpA 0.0041
4976 Apocytochrome f petA 0.0041
6407 Apocytochrome f petA 0.0041
4904 Cytochrome c family protein GSU1996 0.0041
4993 Hydroxylamine oxidoreductase hao1 0.0041
4972 P450cin cinA 0.0041
4764 Cytochrome P450 165C4 CYP165C4 0.0041
4960 Putative cytochrome P450-family protein SCO7417 0.0041
4931 Cytochrome P450 167A1 CYP167A1 0.0041
4926 Heme-based aerotactic transducer hemAT hemAT 0.0041
644 Heme oxygenase 2 HMOX2 0.0041
4982 Heme oxygenase 2 pbsA2 0.0041
4952 Catalase/peroxidase katA 0.0041
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0041
4903 Methyl-accepting chemotaxis protein Tar4 0.0041
3093 Catalase HPII katE 0.0041
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0041
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.004
6645 D-amino-acid oxidase DAO 0.0039
4948 Cytochrome c-553 Not Available 0.0036
4385 Cytochrome c' Not Available 0.0036
4967 Cytochrome c' cycA 0.0036
5038 Cytochrome c' Not Available 0.0036
5223 Cytochrome c' cycP 0.0036
4923 Cytochrome c3 DvMF_2499 0.0036
4945 Cytochrome c3 Not Available 0.0036
4949 Cytochrome c3 DVU_3171 0.0036
4968 Cytochrome c3 cytc3 0.0036
4997 Cytochrome c3 SO_2727 0.0036
5219 Cytochrome c3 cyd 0.0036
4037 Hypothetical protein GPX1 0.0036
4297 Hypothetical protein SP_1951 0.0036
4521 Hypothetical protein BC_2969 0.0036
4540 Hypothetical protein TM_1070 0.0036
4555 Hypothetical protein MT1739 0.0036
4569 Hypothetical protein mshD 0.0036
4578 Hypothetical protein PA3270 0.0036
4747 Hypothetical protein PA3967 0.0036
5177 Hypothetical protein TM_0096 0.0036
5194 Hypothetical protein PA1204 0.0036
5240 Hypothetical protein Rv2991 0.0036
5370 Hypothetical protein TM_1158 0.0036
5710 Hypothetical protein Tb927.5.1360 0.0036
2119 Cytochrome b5 CYB5A 0.0036
4990 PpcA ppcA 0.0036
4992 Cytochrome c peroxidase Not Available 0.0036
4902 Nine-heme cytochrome c Ddes_2038 0.0036
4813 Heme oxygenase hmuO 0.0036
5769 Heme oxygenase Not Available 0.0036
3375 Acidic cytochrome c3 Not Available 0.0036
4988 Sulfite oxidase, mitochondrial SUOX 0.0036
4289 Cytochrome P450 TT_P0059 0.0036
6262 Cytochrome P450 staP 0.0036
3570 Cytochrome P450 152A1 cypC 0.0036
4920 Peroxidase/catalase katG 0.0036
2915 Sensor protein fixL fixL 0.0036
4944 Sensor protein fixL fixL 0.0036
3189 High-molecular-weight cytochrome c hmcA 0.0036
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0036
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0035
3670 Soluble cytochrome b562 precursor cybC 0.0033
3291 Cytochrome c-552 cycA 0.0033
4927 Cytochrome c-552 nrfA 0.0033
4938 Cytochrome c-552 cycA 0.0033
4953 Cytochrome c-552 nrfA 0.0033
5217 Cytochrome c-552 cycM 0.0033
4386 Hemoglobin-like protein HbN glbN 0.0033
2617 Nitric oxide synthase oxygenase nos 0.0033
2701 Nitric oxide synthase oxygenase nos 0.0033
3411 Cytochrome P450 121 cyp121 0.0033
714 Glutathione reductase, mitochondrial GSR 0.0032
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0032
3221 Cytochrome c4 cc4 0.0031
3127 Nitrite reductase nirS 0.0031
3284 Nitrite reductase nirS 0.0031
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0031
2230 Catalase CAT 0.003
3249 Catalase katA 0.003
3625 Catalase katA 0.003
4539 Catalase katA 0.003
4941 Catalase katB 0.003
4608 Putative cytochrome P450 SCO1207 0.003
4963 Putative cytochrome P450 SCO2884 0.003
6254 Putative cytochrome P450 SCO6998 0.003
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0029
2972 6-deoxyerythronolide B hydroxylase eryF 0.0028
4120 NADPH--cytochrome P450 reductase POR 0.0028
260 Cytochrome P450 51 ERG11 0.0028
761 Cytochrome P450 51 ERG11 0.0028
3163 Cytochrome P450 51 cyp51 0.0028
1507 Cytochrome c CYCS 0.0026
6268 Hydroxyacid oxidase 1 HAO1 0.0026
693 Hemoglobin subunit beta HBB 0.0026
518 Peroxidase/catalase T katG 0.0026
810 Heme oxygenase 1 HMOX1 0.0024
3391 Heme oxygenase 1 pbsA1 0.0024
3939 Amine oxidase [flavin-containing] B MAOB 0.0024
3947 Xanthine dehydrogenase/oxidase XDH 0.0024
358 Cystathionine beta-synthase CBS 0.0023
2298 Cytochrome P450-cam camC 0.0022
3941 Amine oxidase [flavin-containing] A MAOA 0.0022
7 Nitric oxide synthase, inducible NOS2 0.0019
291 Nitric-oxide synthase, endothelial NOS3 0.0019
275 Arachidonate 5-lipoxygenase ALOX5 0.0018
6106 Cytochrome P450 2C18 CYP2C18 0.0015
290 Prostaglandin G/H synthase 2 PTGS2 0.0013
20 Prostaglandin G/H synthase 1 PTGS1 0.0012
587 Serum albumin ALB 0.0012
6030 Cytochrome P450 2B6 CYP2B6 0.0011
4924 Cytochrome P450 2C8 CYP2C8 0.001
4757 Cytochrome P450 2C9 CYP2C9 0.001
4512 Cytochrome P450 3A4 CYP3A4 0.0009
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