DT-Web

DB00780 - Phenelzine


Identification
Name Phenelzine
Accession Number DB00780 (APRD00099)
Type small molecule
Description An irreversible non-selective inhibitor of monoamine oxidase. May be used to treat major depressive disorder.
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 136.1943
Groups approved
Monoisotopic Weight 136.100048394
Pharmacology
Indication For the treatment of major depressive disorder. Has also been used with some success in the management of bulimia nervosa.
Mechanism of action Although the exact mechanism of action has not been determined, it appears that the irreversible, nonselective inhibition of MAO by phenelzine relieves depressive symptoms by causing an increase in the levels of serotonin, norepinephrine, and dopamine in the neuron.
Absorption Readily absorbed after oral administration.
Protein binding Not Available
Biotransformation Hepatic. Acetylation of phenelzine appears to be a minor metabolic pathway. Beta-phenylethylamine is a metabolite of phenelzine, and there is indirect evidence that phenelzine may also be ring-hydroxylated and N-methylated.
Route of elimination NARDIL (R) is extensively metabolized, primarily by oxidation via monoamine oxidase.
Toxicity Symptoms of overdose include drowsiness, dizziness, faintness, irritability, hyperactivity, agitation, severe headache, hallucinations, trismus, opisthotonos, convulsions and coma, rapid and irregular pulse, hypertension, hypotension and vascular collapse, precordial pain, respiratory depression and failure, hyperpyrexia, diaphoresis, and cool, clammy skin. Hypertensive crisis may occur with the ingestion of tyramine-rich foods such as cured meats, poultry or fish, aged cheeses, concentrated soy products, tap beer and wine, yeast extracts, broad bean pods and fava beans and sauerkraut.
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions
Drug Mechanism of interaction
Almotriptan The MAO inhibitor, phenelzine, may decrease the metabolism and clearance of the serotonin 5-HT receptor agonist, almotriptan. Concomitant therapy is contraindicated.
Altretamine Risk of severe hypotension
Amitriptyline Possibility of severe adverse effects
Amoxapine Possibility of severe adverse effects
Amphetamine Possible hypertensive crisis
Atomoxetine Possible severe adverse reaction with this combination
Benzphetamine MAO Inhibitors may enhance the hypertensive effect of Amphetamines. Concomitant use of amphetamines and monoamine oxidase inhibitors (MAOI) should be avoided. If used concomitantly, careful monitoring of blood pressure must occur. It may take up to 2 weeks after the discontinuation of an MAOI for the effects to dissipate enough to afford safety to the administration of interacting agents.
Bezafibrate MAO Inhibitors may enhance the adverse/toxic effect of Bezafibrate. Avoid concomitant use of bezafibrate with monoamine oxidase inhibitors (MAOIs) like phenelzine.
Brimonidine MAO Inhibitors like phenelzine may enhance the hypertensive effect of Alpha2-Agonists (Ophthalmic). The concomitant use of monoamine oxidase inhibitors and ophthalmic alpha2 agonists is contraindicated.
Buprenorphine Buprenorphine may enhance the adverse/toxic effect of MAO Inhibitors like phenelzine. When possible, avoid use of buprenorphine in patients who have used a monoamine oxidase inhibitor within the past 14 days due to possible severe adverse effects.
Bupropion Possible severe adverse reaction with this combination
Buspirone Possible blood pressure elevation
Citalopram Possible severe adverse reaction with this combination
Clomipramine Possibility of severe adverse effects
Desipramine Possibility of severe adverse effects
Desvenlafaxine Increased risk of serotonin syndrome. Ensure adequate washout period between therapies to avoid toxicity. Concurrent therapy should be avoided.
Dexfenfluramine Possible hypertensive crisis
Dextroamphetamine Possible hypertensive crisis
Dextromethorphan Possible severe adverse reaction
Diethylpropion Possible hypertensive crisis
Dobutamine Increased arterial pressure
Donepezil Possible antagonism of action
Dopamine Increased arterial pressure
Doxepin Possibility of severe adverse effects
Duloxetine Possible severe adverse reaction with this combination
Entacapone Possible hypertensive crisis with this combination
Ephedra Increased arterial pressure
Ephedrine Increased arterial pressure
Epinephrine Increased arterial pressure
Escitalopram Possible severe adverse reaction with this combination
Fenfluramine Possible hypertensive crisis
Fenoterol Increased arterial pressure
Fluoxetine Possible severe adverse reaction with this combination
Fluvoxamine Possible severe adverse reaction with this combination
Galantamine Possible antagonism of action
Guanethidine Phenelzine may decrease the effect of guanethidine.
Imipramine Possibility of severe adverse effects
Isoproterenol Increased arterial pressure
Levodopa Possible hypertensive crisis
Mazindol Possible hypertensive crisis
Meperidine Potentially fatal adverse effects
Mephentermine Increased arterial pressure
Metaraminol Increased arterial pressure
Methamphetamine Possible hypertensive crisis
Methotrimeprazine Possible severe adverse reaction with this combination
Methoxamine Increased arterial pressure
Methylphenidate Possible hypertensive crisis with this combination
Midodrine Possible hypertensive crisis with this combination
Milnacipran Increase serotonin levels. Combination therapy is contraindicated.
Mirtazapine Possible severe adverse reaction with this combination
Naratriptan The use of two serotonin modulators increases the risk of serotonin syndrome. Consider alternate therapy or monitor for signs and symptoms of serotonin syndrome.
Nefazodone Possible severe adverse reaction with this combination
Norepinephrine Increased arterial pressure
Nortriptyline Possibility of severe adverse effects
Orciprenaline Increased arterial pressure
Paroxetine Possible severe adverse reaction with this combination
Phendimetrazine Possible hypertensive crisis
Phentermine Possible hypertensive crisis
Phenylephrine Increased arterial pressure
Phenylpropanolamine Increased arterial pressure
Pirbuterol Increased arterial pressure
Procaterol Increased arterial pressure
Protriptyline Possibility of severe adverse effects
Pseudoephedrine Increased arterial pressure
Rivastigmine Possible antagonism of action
Rizatriptan The MAO inhibitor, phenelzine, may decrease the metabolism and clearance of the serotonin 5-HT receptor agonist, rizatriptan. Concomitant therapy is contraindicated.
Salbutamol Increased arterial pressure
Sertraline Possible severe adverse reaction with this combination
Sibutramine Possible serotoninergic syndrome with this combination
Sumatriptan The MAO inhibitor, phenelzine, may decrease the metabolism and clearance of the serotonin 5-HT receptor agonist, sumatriptan. Concomitant therapy is contraindicated.
Tacrine The therapeutic effects of the central acetylcholinesterase inhibitor, Tacrine, and/or the anticholinergic, Phenelzine, may be reduced due to antagonism. The interaction may be beneficial when the anticholinergic action is a side effect. Monitor for decreased efficacy of both agents.
Terbutaline Increased arterial pressure
Tetrabenazine Tetrabenazine may increase the adverse/toxic effects of Phenelzine. Concomitant therapy is contraindicated.
Tolcapone Tolcapone and Phenelzine decrease the metabolism of endogenous catecholamines. Concomitant therapy may result in increased catecholamine effects. Consider alternate therapy or use cautiously and monitor for increased catecholamine effects.
Tramadol Tramadol may increase the risk of serotonin syndrome and seizure induction by the MAO inhibitor, phenelzine.
Tranylcypromine Increased risk of serotonin syndrome. Use caution during concomitant therapy and monitor for symptoms of serotonin syndrome.
Trazodone Increased risk of serotonin syndrome. Monitor for symptoms of serotonin syndrome.
Trimethobenzamide Trimethobenzamide and Phenelzine, two anticholinergics, may cause additive anticholinergic effects and enhance their adverse/toxic effects. Monitor for enhanced anticholinergic effects.
Trimipramine Increased risk of serotonin syndrome. Ensure adequate washout period between therapies to avoid toxicity. Avoid combination or monitor for symptoms of serotonin syndrome and/or hypertensive crisis.
Triprolidine Triprolidine and Phenelzine, two anticholinergics, may cause additive anticholinergic effects and enhance their adverse/toxic effects. Additive CNS depressant effects may also occur. Monitor for enhanced anticholinergic and CNS depressant effects.
Trospium Trospium and Phenelzine, two anticholinergics, may cause additive anticholinergic effects and enhanced adverse/toxic effects. Monitor for enhanced anticholinergic effects.
Tryptophanyl-5'amp Possible severe adverse reaction with this combination
Venlafaxine Increased risk of serotonin syndrome. Ensure adequate washout period between therapies to avoid toxicity. Concurrent therapy should be avoided.
Vilazodone MAO Inhibitors may enhance the serotonergic effect of Selective Serotonin Reuptake Inhibitors. This may cause serotonin syndrome.
Zolmitriptan The MAO inhibitor, phenelzine, may increase the serum concentration of zolmitriptan by decreasing its metabolism. Concomitant therapy and use of zolmitriptan within two weeks of discontinuing phenelzine are contraindicated.
Food Interactions
  • Take without regard to meals.
  • Avoid excessive quantities of coffee or tea (Caffeine).
  • Avoid aged foods (cheese, red wine), pickled foods, cured foods (bacon/ham), chocolate, fava beans, beer, unless approved by your physician.
  • Avoid St.John's Wort.
  • Avoid alcohol.

Targets


Amine oxidase [flavin-containing] A
Name Amine oxidase [flavin-containing] A
Gene Name MAOA
Pharmacological action yes
Actions antagonist
References
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
  • Chiche F, Le Guillou M, Chetrite G, Lasnier F, Dugail I, Carpene C, Moldes M, Feve B: Antidepressant phenelzine alters differentiation of cultured human and mouse preadipocytes. Mol Pharmacol. 2009 May;75(5):1052-61. Epub 2009 Feb 6. - Pubmed
  • Chenu F, El Mansari M, Blier P: Long-term administration of monoamine oxidase inhibitors alters the firing rate and pattern of dopamine neurons in the ventral tegmental area. Int J Neuropsychopharmacol. 2009 May;12(4):475-85. Epub 2008 Aug 13. - Pubmed
  • Wooters TE, Bardo MT: The monoamine oxidase inhibitor phenelzine enhances the discriminative stimulus effect of nicotine in rats. Behav Pharmacol. 2007 Nov;18(7):601-8. - Pubmed
  • Volz HP, Gleiter CH: Monoamine oxidase inhibitors. A perspective on their use in the elderly. Drugs Aging. 1998 Nov;13(5):341-55. - Pubmed
  • Nolen WA: [Classical monoamine oxidase inhibitor: not registered for, but still a place in the treatment of depression] Ned Tijdschr Geneeskd. 2003 Oct 4;147(40):1940-3. - Pubmed
  • Pickar D, Murphy DL, Cohen RM, Campbell IC, Lipper S: Selective and nonselective monoamine oxidase inhibitors: behavioral disturbances during their administration to depressed patients. Arch Gen Psychiatry. 1982 May;39(5):535-40. - Pubmed
  • MacKenzie EM, Grant SL, Baker GB, Wood PL: Phenelzine causes an increase in brain ornithine that is prevented by prior monoamine oxidase inhibition. Neurochem Res. 2008 Mar;33(3):430-6. Epub 2007 Aug 31. - Pubmed
  • McIntyre RS, Soczynska JK, Konarski JZ, Kennedy SH: The effect of antidepressants on glucose homeostasis and insulin sensitivity: synthesis and mechanisms. Expert Opin Drug Saf. 2006 Jan;5(1):157-68. - Pubmed
DTHybrid score 0.6425
Amine oxidase [flavin-containing] B
Name Amine oxidase [flavin-containing] B
Gene Name MAOB
Pharmacological action yes
Actions antagonist
References
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
  • Chiche F, Le Guillou M, Chetrite G, Lasnier F, Dugail I, Carpene C, Moldes M, Feve B: Antidepressant phenelzine alters differentiation of cultured human and mouse preadipocytes. Mol Pharmacol. 2009 May;75(5):1052-61. Epub 2009 Feb 6. - Pubmed
  • Chenu F, El Mansari M, Blier P: Long-term administration of monoamine oxidase inhibitors alters the firing rate and pattern of dopamine neurons in the ventral tegmental area. Int J Neuropsychopharmacol. 2009 May;12(4):475-85. Epub 2008 Aug 13. - Pubmed
  • Wooters TE, Bardo MT: The monoamine oxidase inhibitor phenelzine enhances the discriminative stimulus effect of nicotine in rats. Behav Pharmacol. 2007 Nov;18(7):601-8. - Pubmed
  • Volz HP, Gleiter CH: Monoamine oxidase inhibitors. A perspective on their use in the elderly. Drugs Aging. 1998 Nov;13(5):341-55. - Pubmed
  • Nolen WA: [Classical monoamine oxidase inhibitor: not registered for, but still a place in the treatment of depression] Ned Tijdschr Geneeskd. 2003 Oct 4;147(40):1940-3. - Pubmed
  • Pickar D, Murphy DL, Cohen RM, Campbell IC, Lipper S: Selective and nonselective monoamine oxidase inhibitors: behavioral disturbances during their administration to depressed patients. Arch Gen Psychiatry. 1982 May;39(5):535-40. - Pubmed
  • McIntyre RS, Soczynska JK, Konarski JZ, Kennedy SH: The effect of antidepressants on glucose homeostasis and insulin sensitivity: synthesis and mechanisms. Expert Opin Drug Saf. 2006 Jan;5(1):157-68. - Pubmed
DTHybrid score 1.0404
Membrane copper amine oxidase
Name Membrane copper amine oxidase
Gene Name AOC3
Pharmacological action unknown
Actions inhibitor
References
  • Tipnis UR, Tao M, Boor PJ: Purification and characterization of semicarbazide-sensitive amine oxidase from porcine aorta. Cell Mol Biol (Noisy-le-grand). 1992 Aug-Sep;38(5-6):575-84. - Pubmed
  • Kumar D, Trent MB, Boor PJ: Allylamine and beta-aminopropionitrile induced aortic medial necrosis: mechanisms of synergism. Toxicology. 1998 Feb 6;125(2-3):107-15. - Pubmed
  • Chiche F, Le Guillou M, Chetrite G, Lasnier F, Dugail I, Carpene C, Moldes M, Feve B: Antidepressant phenelzine alters differentiation of cultured human and mouse preadipocytes. Mol Pharmacol. 2009 May;75(5):1052-61. Epub 2009 Feb 6. - Pubmed
  • Biasi D, Caramaschi P, Pacor ML, Carletto A, Melchiori S, Manzo T, Bambara LM: [Multiple osseous avascular necrosis in a patient with systemic lupus erythematosus with antiphospholipid antibody positivity] Recenti Prog Med. 1995 Nov;86(11):449-50. - Pubmed
  • MacKenzie EM, Grant SL, Baker GB, Wood PL: Phenelzine causes an increase in brain ornithine that is prevented by prior monoamine oxidase inhibition. Neurochem Res. 2008 Mar;33(3):430-6. Epub 2007 Aug 31. - Pubmed
  • Lizcano JM, Fernandez de Arriba A, Tipton KF, Unzeta M: Inhibition of bovine lung semicarbazide-sensitive amine oxidase (SSAO) by some hydrazine derivatives. Biochem Pharmacol. 1996 Jul 26;52(2):187-95. - Pubmed
DTHybrid score 0.5069
4-aminobutyrate aminotransferase, mitochondrial
Name 4-aminobutyrate aminotransferase, mitochondrial
Gene Name ABAT
Pharmacological action unknown
Actions inhibitor
References
  • MacKenzie EM, Grant SL, Baker GB, Wood PL: Phenelzine causes an increase in brain ornithine that is prevented by prior monoamine oxidase inhibition. Neurochem Res. 2008 Mar;33(3):430-6. Epub 2007 Aug 31. - Pubmed
  • Tanay VA, Parent MB, Wong JT, Paslawski T, Martin IL, Baker GB: Effects of the antidepressant/antipanic drug phenelzine on alanine and alanine transaminase in rat brain. Cell Mol Neurobiol. 2001 Aug;21(4):325-39. - Pubmed
  • McKenna KF, McManus DJ, Baker GB, Coutts RT: Chronic administration of the antidepressant phenelzine and its N-acetyl analogue: effects on GABAergic function. J Neural Transm Suppl. 1994;41:115-22. - Pubmed
  • McManus DJ, Baker GB, Martin IL, Greenshaw AJ, McKenna KF: Effects of the antidepressant/antipanic drug phenelzine on GABA concentrations and GABA-transaminase activity in rat brain. Biochem Pharmacol. 1992 Jun 9;43(11):2486-9. - Pubmed
  • Todd KG, Baker GB: GABA-elevating effects of the antidepressant/antipanic drug phenelzine in brain: effects of pretreatment with tranylcypromine, (-)-deprenyl and clorgyline. J Affect Disord. 1995 Dec 13;35(3):125-9. - Pubmed
  • Todd KG, Baker GB: Neurochemical effects of the monoamine oxidase inhibitor phenelzine on brain GABA and alanine: A comparison with vigabatrin. J Pharm Pharm Sci. 2008 May 16;11(2):14s-21s. - Pubmed
  • McKenna KF, Baker GB, Coutts RT: N2-acetylphenelzine: effects on rat brain GABA, alanine and biogenic amines. Naunyn Schmiedebergs Arch Pharmacol. 1991 May;343(5):478-82. - Pubmed
DTHybrid score 0.6024
Alanine aminotransferase 1
Name Alanine aminotransferase 1
Gene Name GPT
Pharmacological action unknown
Actions inhibitor
References
  • Todd KG, Baker GB: Neurochemical effects of the monoamine oxidase inhibitor phenelzine on brain GABA and alanine: A comparison with vigabatrin. J Pharm Pharm Sci. 2008 May 16;11(2):14s-21s. - Pubmed
  • Tanay VA, Parent MB, Wong JT, Paslawski T, Martin IL, Baker GB: Effects of the antidepressant/antipanic drug phenelzine on alanine and alanine transaminase in rat brain. Cell Mol Neurobiol. 2001 Aug;21(4):325-39. - Pubmed
  • McKenna KF, Baker GB, Coutts RT: N2-acetylphenelzine: effects on rat brain GABA, alanine and biogenic amines. Naunyn Schmiedebergs Arch Pharmacol. 1991 May;343(5):478-82. - Pubmed
DTHybrid score 0.2411
Alanine aminotransferase 2
Name Alanine aminotransferase 2
Gene Name GPT2
Pharmacological action unknown
Actions inhibitor
References
  • Todd KG, Baker GB: Neurochemical effects of the monoamine oxidase inhibitor phenelzine on brain GABA and alanine: A comparison with vigabatrin. J Pharm Pharm Sci. 2008 May 16;11(2):14s-21s. - Pubmed
  • Tanay VA, Parent MB, Wong JT, Paslawski T, Martin IL, Baker GB: Effects of the antidepressant/antipanic drug phenelzine on alanine and alanine transaminase in rat brain. Cell Mol Neurobiol. 2001 Aug;21(4):325-39. - Pubmed
  • McKenna KF, Baker GB, Coutts RT: N2-acetylphenelzine: effects on rat brain GABA, alanine and biogenic amines. Naunyn Schmiedebergs Arch Pharmacol. 1991 May;343(5):478-82. - Pubmed
DTHybrid score 0.2411
Glutamic acid decarboxylase
Name Glutamic acid decarboxylase
Gene Name GAD65
Pharmacological action unknown
Actions inhibitor
References
  • McKenna KF, McManus DJ, Baker GB, Coutts RT: Chronic administration of the antidepressant phenelzine and its N-acetyl analogue: effects on GABAergic function. J Neural Transm Suppl. 1994;41:115-22. - Pubmed
DTHybrid score 0.2039

Enzymes


Amine oxidase [flavin-containing] A
Name Amine oxidase [flavin-containing] A
Gene Name MAOA
Actions substrate
References
  • MacKenzie EM, Grant SL, Baker GB, Wood PL: Phenelzine causes an increase in brain ornithine that is prevented by prior monoamine oxidase inhibition. Neurochem Res. 2008 Mar;33(3):430-6. Epub 2007 Aug 31. - Pubmed
DTHybrid score 0.6425
Cytochrome P450 2E1
Name Cytochrome P450 2E1
Gene Name CYP2E1
Actions inducer
References
  • -
  • Runge-Morris M, Feng Y, Zangar RC, Novak RF: Effects of hydrazine, phenelzine, and hydralazine treatment on rat hepatic and renal drug-metabolizing enzyme expression. Drug Metab Dispos. 1996 Jul;24(7):734-7. - Pubmed
DTHybrid score 0.3585
Amine oxidase [flavin-containing] B
Name Amine oxidase [flavin-containing] B
Gene Name MAOB
Actions substrate
References
  • MacKenzie EM, Grant SL, Baker GB, Wood PL: Phenelzine causes an increase in brain ornithine that is prevented by prior monoamine oxidase inhibition. Neurochem Res. 2008 Mar;33(3):430-6. Epub 2007 Aug 31. - Pubmed
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
DTHybrid score 1.0404
Cytochrome P450 2C19
Name Cytochrome P450 2C19
Gene Name CYP2C19
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4709
Cytochrome P450 2C8
Name Cytochrome P450 2C8
Gene Name CYP2C8
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3962
Cytochrome P450 3A4
Name Cytochrome P450 3A4
Gene Name CYP3A4
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.7699
Cytochrome P450 3A43
Name Cytochrome P450 3A43
Gene Name CYP3A43
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.2556
Cytochrome P450 3A5
Name Cytochrome P450 3A5
Gene Name CYP3A5
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4955
Cytochrome P450 3A7
Name Cytochrome P450 3A7
Gene Name CYP3A7
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4125

Predictions


Id Partner name Gene Name Score
4757 Cytochrome P450 2C9 CYP2C9 0.3725
4119 Cytochrome P450 2D6 CYP2D6 0.3397
4200 Cytochrome P450 1A2 CYP1A2 0.288
1588 Multidrug resistance protein 1 ABCB1 0.2672
6030 Cytochrome P450 2B6 CYP2B6 0.1781
3330 Phenylethylamine oxidase Not Available 0.1363
5718 Cytochrome P450 2A6 CYP2A6 0.1219
2255 Copper amine oxidase tynA 0.1218
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.1184
6024 Cytochrome P450 1A1 CYP1A1 0.1097
824 Sodium-dependent serotonin transporter SLC6A4 0.1017
593 Proton-coupled amino acid transporter 1 SLC36A1 0.096
3899 Alanine--glyoxylate aminotransferase 2-like 2 AGXT2L2 0.0845
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.084
587 Serum albumin ALB 0.0803
114 Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 0.0803
713 Sodium-dependent dopamine transporter SLC6A3 0.0785
169 Cysteine desulfurase, mitochondrial NFS1 0.0775
435 Kynureninase KYNU 0.077
4654 Kynureninase kynU 0.077
532 Neutral amino acid transporter A SLC1A4 0.0755
323 Alanyl-tRNA synthetase, cytoplasmic AARS 0.0755
4070 Probable alanyl-tRNA synthetase, mitochondrial AARS2 0.0755
20 Prostaglandin G/H synthase 1 PTGS1 0.0717
6106 Cytochrome P450 2C18 CYP2C18 0.0713
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0696
3811 Cytochrome P450 19A1 CYP19A1 0.0678
349 Serine--pyruvate aminotransferase AGXT 0.0642
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0639
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0631
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0627
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0556
240 Gamma-aminobutyric acid type B receptor, subunit 1 GABBR1 0.054
866 Large neutral amino acids transporter small subunit 2 SLC7A8 0.0531
1729 Solute carrier family 22 member 6 SLC22A6 0.0519
862 Multidrug resistance-associated protein 1 ABCC1 0.05
6151 Monocarboxylate transporter 10 SLC16A10 0.0494
556 Alpha-1A adrenergic receptor ADRA1A 0.049
6145 Solute carrier family 22 member 1 SLC22A1 0.0473
492 Histamine H1 receptor HRH1 0.0471
1898 Cytochrome P450 1B1 CYP1B1 0.0466
318 Alpha-2A adrenergic receptor ADRA2A 0.0461
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0446
6143 Solute carrier family 22 member 7 SLC22A7 0.0438
502 5-hydroxytryptamine 2A receptor HTR2A 0.0432
320 5-hydroxytryptamine 1A receptor HTR1A 0.0431
885 5-hydroxytryptamine 1B receptor HTR1B 0.0418
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0413
776 Bile salt export pump ABCB11 0.0411
831 D(2) dopamine receptor DRD2 0.0405
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0398
6144 Solute carrier family 22 member 2 SLC22A2 0.0394
725 5-hydroxytryptamine 1D receptor HTR1D 0.039
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0382
131 Synaptic vesicular amine transporter SLC18A2 0.0372
847 Mu-type opioid receptor OPRM1 0.0368
871 Glucocorticoid receptor NR3C1 0.0365
260 Cytochrome P450 51 ERG11 0.0354
761 Cytochrome P450 51 ERG11 0.0354
3163 Cytochrome P450 51 cyp51 0.0354
146 Androgen receptor AR 0.0346
420 Glutamate decarboxylase 1 GAD1 0.0343
3900 Glutamate decarboxylase 1 GAD1 0.0343
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0341
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0338
511 5-hydroxytryptamine 1F receptor HTR1F 0.0337
801 Kynurenine/alpha-aminoadipate aminotransferase mitochondrial AADAT 0.0336
665 Phosphoserine aminotransferase PSAT1 0.0336
4652 Phosphoserine aminotransferase serC 0.0336
3895 Kynurenine--oxoglutarate transaminase 3 CCBL2 0.0336
3810 Catechol O-methyltransferase COMT 0.0334
6147 Solute carrier family 22 member 3 SLC22A3 0.0333
23 D(1A) dopamine receptor DRD1 0.0327
290 Prostaglandin G/H synthase 2 PTGS2 0.0324
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0322
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0321
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.032
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0319
468 Cytochrome P450 4A11 CYP4A11 0.0312
208 DNA-directed RNA polymerase beta' chain rpoC 0.0311
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0311
118 Organic cation/carnitine transporter 2 SLC22A5 0.0307
3877 Growth-inhibiting protein 18 GIG18 0.0302
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0301
763 Tyrosine aminotransferase TAT 0.0296
5493 Tyrosine aminotransferase Not Available 0.0296
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0294
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.029
426 Aspartate aminotransferase, mitochondrial GOT2 0.0286
6142 Solute carrier family 22 member 8 SLC22A8 0.0285
914 Formimidoyltransferase-cyclodeaminase FTCD 0.0278
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0273
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0271
766 Beta-2 adrenergic receptor ADRB2 0.0271
467 Delta-type opioid receptor OPRD1 0.0269
731 HIV-1 protease HIV-1 protease 0.0269
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0266
632 Alpha-1B adrenergic receptor ADRA1B 0.0266
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0265
51 Muscarinic acetylcholine receptor M3 CHRM3 0.026
3878 GAD1 protein GAD1 0.0256
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0255
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0255
3908 P-selectin cytoplasmic tail-associated protein pcap 0.0253
193 Beta-1 adrenergic receptor ADRB1 0.0253
3896 CDNA FLJ46802 fis, clone TRACH3032150, moderately similar to Cysteine sulfinic acid decarboxylase GADL1 0.0253
3915 Cysteine sulfinic acid decarboxylase-related protein 1 CSAD 0.0253
3911 Uncharacterized protein C20orf38 SPTLC3 0.0252
3906 Serine dehydratase-like SDSL 0.0252
3891 Putative L-Dopa decarboxylase DDC 0.0252
3887 Phosphorylase PYGB 0.0252
3881 Selenocysteine lyase variant Not Available 0.0252
3883 Ornithine aminotransferase variant Not Available 0.0252
306 Pyridoxal phosphate phosphatase PDXP 0.0252
3914 Alanine-glyoxylate aminotransferase homolog TLH6 0.0252
3893 DDC protein DDC 0.0252
3910 O-phosphoseryl-tRNA(Sec) selenium transferase SEPSECS 0.0252
3909 Hepatic peroxysomal alanine:glyoxylate aminotransferase Not Available 0.0252
3880 Serine hydroxymethyltransferase 1 Not Available 0.0252
3903 Aminolevulinate, delta-, synthase 2 ALAS2 0.0252
855 Sphingosine-1-phosphate lyase 1 SGPL1 0.0252
3894 KIAA0251 protein PDXDC1 0.0252
3886 Migration-inducing protein 4 ALAS1 0.0252
3875 Glycogen phosphorylase, brain form PYGB 0.0252
3882 Brain glycogen phosphorylase variant Not Available 0.0252
3905 Molybdenum cofactor sulfurase MOCOS 0.0252
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.0251
574 Branched-chain-amino-acid aminotransferase, cytosolic BCAT1 0.0245
696 Kappa-type opioid receptor OPRK1 0.0244
136 Estrogen receptor ESR1 0.0243
2164 Multidrug resistance-associated protein 4 ABCC4 0.0242
590 5-hydroxytryptamine 2C receptor HTR2C 0.0241
638 D(3) dopamine receptor DRD3 0.0239
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0239
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0238
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0236
2864 Penton protein PIII 0.0236
738 Monocarboxylate transporter 1 SLC16A1 0.0235
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0233
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0231
378 Alpha-2C adrenergic receptor ADRA2C 0.023
341 5-hydroxytryptamine 3 receptor HTR3A 0.0222
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0218
833 Organic cation/carnitine transporter 1 SLC22A4 0.0217
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0216
629 Alpha-2B adrenergic receptor ADRA2B 0.0215
6182 Cytochrome P450 2J2 CYP2J2 0.0215
705 Glutamate receptor 1 GRIA1 0.0213
3 Histidine decarboxylase HDC 0.021
6174 50S ribosomal protein L32 rpmF 0.0209
273 Apoptosis regulator Bcl-2 BCL2 0.0208
89 Cysteine sulfinic acid decarboxylase CSAD 0.0207
184 L-serine dehydratase SDS 0.0207
431 Serine racemase SRR 0.0206
491 Serine palmitoyltransferase 1 SPTLC1 0.0206
727 Serine palmitoyltransferase 2 SPTLC2 0.0206
5841 Insulin-like growth factor IB IGF1 0.0206
534 Threonine synthase-like 1 THNSL1 0.0206
3874 Proline synthetase co-transcribed bacterial homolog protein PROSC 0.0205
499 Arginine decarboxylase ADC 0.0205
575 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial GCAT 0.0204
455 5-aminolevulinate synthase, nonspecific, mitochondrial ALAS1 0.0204
681 Glycine dehydrogenase [decarboxylating], mitochondrial GLDC 0.0204
358 Cystathionine beta-synthase CBS 0.0204
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0203
3876 Aromatic-L-amino-acid decarboxylase DDC 0.02
789 Alpha-1D adrenergic receptor ADRA1D 0.0199
442 Envelope glycoprotein gp41 0.0198
4859 Envelope glycoprotein env 0.0198
1757 Myeloperoxidase MPO 0.0197
614 Progesterone receptor PGR 0.0195
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0195
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0194
756 Sex hormone-binding globulin SHBG 0.019
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.019
6014 Cytochrome P450 2A13 CYP2A13 0.0187
811 Translocator protein TSPO 0.0186
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0184
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0184
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0184
3884 SHMT2 protein SHMT2 0.0183
3901 SHMT2 protein SHMT2 0.0183
3885 Hypothetical protein DKFZp686P09201 DKFZp686P09201 0.0183
3879 Serine hydroxymethyltransferase 2 Not Available 0.0183
321 Serine hydroxymethyltransferase, mitochondrial SHMT2 0.0183
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0183
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0182
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0181
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0181
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0181
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0181
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0179
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0178
6148 Multidrug resistance-associated protein 7 ABCC10 0.0178
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0178
472 Ornithine aminotransferase, mitochondrial OAT 0.0177
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0176
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0174
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0174
203 Pyridoxine-5'-phosphate oxidase PNPO 0.0173
6141 Sodium/bile acid cotransporter SLC10A1 0.0173
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0173
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0172
737 Mineralocorticoid receptor NR3C2 0.017
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.017
465 Calmodulin CALM1 0.0169
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0169
817 DNA topoisomerase 2-alpha TOP2A 0.0169
301 Kynurenine--oxoglutarate transaminase 1 CCBL1 0.0168
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0166
868 Cystathionine gamma-lyase CTH 0.0166
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0161
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0159
380 Cytochrome P450 17A1 CYP17A1 0.0158
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0154
367 Serine hydroxymethyltransferase, cytosolic SHMT1 0.0154
432 D(4) dopamine receptor DRD4 0.0153
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0151
6136 Multidrug resistance-associated protein 5 ABCC5 0.0151
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0151
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0151
4024 Mitochondrial glutamate carrier 2 SLC25A18 0.015
4025 Mitochondrial glutamate carrier 1 SLC25A22 0.015
664 Glutamate decarboxylase 2 GAD2 0.015
3890 Glutamate decarboxylase 2 GAD2 0.015
4019 Excitatory amino acid transporter 4 SLC1A6 0.015
4026 Aspartyl aminopeptidase DNPEP 0.015
4021 Probable glutamyl-tRNA synthetase, mitochondrial EARS2 0.015
4016 Excitatory amino acid transporter 5 SLC1A7 0.015
4023 N-acetylglutamate synthase, mitochondrial NAGS 0.015
4022 Glutamate--ammonia ligase domain-containing protein 1 LGSN 0.015
1047 Excitatory amino acid transporter 2 SLC1A2 0.015
1912 Excitatory amino acid transporter 1 SLC1A3 0.015
915 Delta 1-pyrroline-5-carboxylate synthetase ALDH18A1 0.015
919 Glutamate receptor, ionotropic kainate 4 GRIK4 0.015
927 Metabotropic glutamate receptor 8 GRM8 0.015
4018 Glutamate receptor delta-2 subunit GRID2 0.015
4027 Glutamate receptor delta-1 subunit GRID1 0.015
4020 Glutamyl aminopeptidase ENPEP 0.015
922 Glutamate receptor 4 GRIA4 0.015
925 Metabotropic glutamate receptor 4 GRM4 0.015
926 Metabotropic glutamate receptor 7 GRM7 0.015
924 Glutamate receptor, ionotropic kainate 3 GRIK3 0.015
920 Glutamate receptor, ionotropic kainate 5 GRIK5 0.015
4017 5-oxoprolinase OPLAH 0.015
449 Ornithine decarboxylase ODC1 0.015
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0148
1656 CYP2B protein CYP2B 0.0147
4148 Serine/threonine-protein kinase mTOR MTOR 0.0145
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0145
232 Corticosteroid-binding globulin SERPINA6 0.0143
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0143
4773 Deoxycytidine kinase DCK 0.0142
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0142
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0138
921 Glutamate receptor 2 GRIA2 0.0138
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0137
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0137
6102 Arylamine N-acetyltransferase 2 NAT2 0.0136
1010 Cytochrome P450 51A1 CYP51A1 0.0134
844 Epidermal growth factor receptor EGFR 0.0133
777 Tumor necrosis factor TNF 0.0132
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0132
469 Annexin A1 ANXA1 0.0131
29 Tubulin beta-1 chain TUBB1 0.013
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0129
10 Glycogen phosphorylase, liver form PYGL 0.0128
668 Glutamate--cysteine ligase regulatory subunit GCLM 0.0128
5 Glutaminase liver isoform, mitochondrial GLS2 0.0126
917 Glutaminase kidney isoform, mitochondrial GLS 0.0126
3984 Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial PET112L 0.0126
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0126
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0126
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0126
3991 Glutamine-dependent NAD(+) synthetase NADSYN1 0.0126
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0126
5261 Phosphoribosylformylglycinamidine synthase purL 0.0126
218 Monocarboxylate transporter 5 SLC16A4 0.0126
397 Monocarboxylate transporter 3 SLC16A8 0.0126
429 Monocarboxylate transporter 6 SLC16A5 0.0126
195 Monocarboxylate transporter 7 SLC16A6 0.0126
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0125
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0125
122 P2Y purinoceptor 12 P2RY12 0.0125
504 Mast/stem cell growth factor receptor KIT 0.0123
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0122
4604 Liver carboxylesterase 1 CES1 0.0122
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0122
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0122
1024 Solute carrier family 22 member 11 SLC22A11 0.0121
6020 Aldehyde oxidase AOX1 0.012
84 Nuclear receptor 0B1 NR0B1 0.012
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.012
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.012
625 Glutamate carboxypeptidase 2 FOLH1 0.0119
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0119
94 5-hydroxytryptamine 4 receptor HTR4 0.0117
33 Cystine/glutamate transporter SLC7A11 0.0117
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0117
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0116
6220 Aryl hydrocarbon receptor AHR 0.0116
642 3-oxo-5-alpha-steroid 4-dehydrogenase 2 SRD5A2 0.0115
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0115
16 Adenosine A1 receptor ADORA1 0.0114
153 Dopamine beta-hydroxylase DBH 0.0113
1671 Excitatory amino acid transporter 3 SLC1A1 0.0113
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0112
186 Glutamate--cysteine ligase catalytic subunit GCLC 0.0112
916 Metabotropic glutamate receptor 1 GRM1 0.0112
26 Vascular endothelial growth factor receptor 3 FLT4 0.0111
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.011
284 DNA-directed RNA polymerase beta chain rpoB 0.011
5773 DNA-directed RNA polymerase beta chain rpoB 0.011
818 50S ribosomal protein L10 rplJ 0.0109
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0108
3426 Glutamine synthetase glnA 0.0108
3987 Glutamine synthetase GLUL 0.0108
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0107
407 Vascular endothelial growth factor receptor 2 KDR 0.0106
1517 Beta-3 adrenergic receptor ADRB3 0.0106
32 Vascular endothelial growth factor receptor 1 FLT1 0.0106
923 Glutamate receptor 3 GRIA3 0.0106
5698 Riboflavin synthase alpha chain ribE 0.0105
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0105
199 Monocarboxylate transporter 8 SLC16A2 0.0104
52 Pyruvate kinase isozymes R/L PKLR 0.0104
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0103
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0103
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0102
1039 Histone deacetylase 9 HDAC9 0.0102
408 Riboflavin kinase RFK 0.0101
436 5-hydroxytryptamine 2B receptor HTR2B 0.0101
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0101
771 Pyruvate carboxylase, mitochondrial PC 0.0101
161 Tubulin beta chain TUBB 0.0101
312 Tubulin beta chain TUB2 0.0101
228 Beta platelet-derived growth factor receptor PDGFRB 0.0101
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.01
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.01
4120 NADPH--cytochrome P450 reductase POR 0.0099
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0099
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0099
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0098
489 Monocarboxylate transporter 2 SLC16A7 0.0098
716 5-hydroxytryptamine 7 receptor HTR7 0.0098
427 Substance-P receptor TACR1 0.0097
163 D(1B) dopamine receptor DRD5 0.0096
6137 Multidrug resistance-associated protein 6 ABCC6 0.0096
723 Cytosolic phospholipase A2 PLA2G4A 0.0096
1152 Glycogen phosphorylase, muscle form PYGM 0.0096
210 Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase EPRS 0.0096
592 Carbonic anhydrase 4 CA4 0.0096
2539 Tubulin alpha-1 chain TUBA4A 0.0095
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0095
3923 Cholinesterase BCHE 0.0092
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0092
295 Carbonic anhydrase 1 CA1 0.0092
3917 Methylenetetrahydrofolate reductase MTHFR 0.0092
1178 Adenosine A2a receptor ADORA2A 0.0091
98 Pyruvate kinase isozymes M1/M2 PKM2 0.0091
952 Dipeptidyl peptidase 4 DPP4 0.0091
124 Histamine H2 receptor HRH2 0.0091
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0089
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0089
70 Type-1 angiotensin II receptor AGTR1 0.0089
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0088
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0088
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0088
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0087
869 Estrogen receptor beta ESR2 0.0086
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0086
1256 5-hydroxytryptamine 6 receptor HTR6 0.0085
891 Dihydropteroate synthase folP 0.0085
5359 Dihydropteroate synthase folP 0.0085
7175 Dihydropteroate synthase sulI 0.0085
500 Monocarboxylate transporter 4 SLC16A3 0.0084
482 Glycine receptor subunit alpha-1 GLRA1 0.0083
768 FK506-binding protein 1A FKBP1A 0.0083
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0083
4122 Histone deacetylase 2 HDAC2 0.0082
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.0082
1636 Trace amine-associated receptor 1 TAAR1 0.0081
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.008
5300 Antigen peptide transporter 1 TAP1 0.008
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0079
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0077
814 Ryanodine receptor 1 RYR1 0.0077
6126 Carbonic anhydrase 7 CA7 0.0076
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0075
654 Flavin reductase BLVRB 0.0075
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0074
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0074
477 DNA topoisomerase 4 subunit A parC 0.0074
886 DNA topoisomerase 4 subunit A parC 0.0074
6226 DNA topoisomerase 4 subunit A parC 0.0074
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0074
613 Atrial natriuretic peptide receptor A NPR1 0.0074
373 Transthyretin TTR 0.0073
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0073
357 Carbonic anhydrase 2 CA2 0.0073
404 DNA gyrase subunit A gyrA 0.0073
6224 DNA gyrase subunit A gyrA 0.0073
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0073
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0072
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0072
1050 Bile salt sulfotransferase SULT2A1 0.0072
3601 Dihydropteroate synthase 1 folP1 0.0071
3807 Dihydropteroate synthase 1 folP1 0.0071
3808 Dihydropteroate synthase 2 folP2 0.0071
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0071
365 Dihydrofolate reductase DHFR 0.007
2381 Dihydrofolate reductase DFR1 0.007
2833 Dihydrofolate reductase Not Available 0.007
2931 Dihydrofolate reductase folA 0.007
3544 Dihydrofolate reductase folA 0.007
3682 Dihydrofolate reductase folA 0.007
6642 Dihydrofolate reductase folA 0.007
6756 Dihydrofolate reductase dfrA 0.007
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.007
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.007
165 FL cytokine receptor FLT3 0.0069
1196 Complement decay-accelerating factor CD55 0.0069
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0069
823 Fibroblast growth factor receptor 2 FGFR2 0.0069
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0069
4116 Dihydropteroate synthetase Not Available 0.0069
537 ATP synthase delta chain, mitochondrial ATP5D 0.0068
4237 50S ribosomal protein L22 rplV 0.0068
3947 Xanthine dehydrogenase/oxidase XDH 0.0068
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0067
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0066
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0065
3932 Glutathione S-transferase A2 GSTA2 0.0065
528 5-hydroxytryptamine 1E receptor HTR1E 0.0065
474 Acetylcholinesterase ACHE 0.0064
7 Nitric oxide synthase, inducible NOS2 0.0063
319 Opioid receptor, sigma 1 OPRS1 0.0062
6105 3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 0.0062
239 Coagulation factor X F10 0.0062
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0062
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0062
2183 Fatty acid-binding protein, adipocyte FABP4 0.0061
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0061
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0061
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0061
1852 Microtubule-associated protein 2 MAP2 0.0061
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0061
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.006
4311 tRNA TRDMT1 0.006
4325 tRNA trmD 0.006
4328 tRNA trmD 0.006
2808 Chloramphenicol acetyltransferase 3 cat3 0.006
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0059
976 Platelet glycoprotein IX GP9 0.0059
694 Matrix protein 2 M 0.0059
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0059
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0058
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0057
518 Peroxidase/catalase T katG 0.0056
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0056
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0056
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0056
6131 Carbonic anhydrase 14 CA14 0.0055
2417 Chloramphenicol acetyltransferase cat 0.0055
3278 Chloramphenicol acetyltransferase cat 0.0055
5923 Microtubule-associated protein tau MAPT 0.0055
5924 Microtubule-associated protein 4 MAP4 0.0055
1618 High affinity nerve growth factor receptor NTRK1 0.0055
2268 Cholesterol oxidase choB 0.0054
2822 Cholesterol oxidase choA 0.0054
2810 Dr hemagglutinin structural subunit draA 0.0054
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0054
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0054
4238 50S ribosomal protein L4 rplD 0.0054
5578 50S ribosomal protein L4 rplD 0.0054
6173 50S ribosomal protein L4 rplD 0.0054
6219 50S ribosomal protein L4 rplD 0.0054
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0054
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0054
3086 Plasmepsin-2 Not Available 0.0053
444 Alcohol dehydrogenase 1B ADH1B 0.0053
1192 Sulfotransferase 1A1 SULT1A1 0.0053
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0053
174 Sigma 1-type opioid receptor SIGMAR1 0.0052
49 Endothelin B receptor EDNRB 0.0052
251 Alcohol dehydrogenase 1A ADH1A 0.0052
6122 Carbonic anhydrase 3 CA3 0.0052
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0052
3090 Chitosanase csn 0.0052
4149 Nuclear factor NF-kappa-B p100 subunit NFKB2 0.0052
275 Arachidonate 5-lipoxygenase ALOX5 0.0051
3823 Cytokine receptor common gamma chain IL2RG 0.0051
88 Retinoic acid receptor RXR-beta RXRB 0.0051
6085 Fatty acid-binding protein, intestinal FABP2 0.0051
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0051
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0051
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.005
3809 Estrogen-related receptor gamma ESRRG 0.005
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.005
856 Vitamin D3 receptor VDR 0.005
1541 Metalloproteinase mmp20 0.0049
578 Endothelin-1 receptor EDNRA 0.0049
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0049
68 Cannabinoid receptor 1 CNR1 0.0048
6138 Multidrug resistance protein 3 ABCB4 0.0048
904 Glutathione S-transferase P GSTP1 0.0048
1630 Integrin beta-2 ITGB2 0.0047
1253 Interferon gamma IFNG 0.0046
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0046
4203 Histamine N-methyltransferase HNMT 0.0046
6134 Sodium channel subunit beta-3 SCN3B 0.0045
6133 Sodium channel subunit beta-2 SCN2B 0.0045
6132 Sodium channel subunit beta-1 SCN1B 0.0045
6135 Sodium channel subunit beta-4 SCN4B 0.0045
6127 Carbonic anhydrase-related protein CA8 0.0045
6129 Carbonic anhydrase-related protein 11 CA11 0.0045
6128 Carbonic anhydrase-related protein 10 CA10 0.0045
2230 Catalase CAT 0.0045
3249 Catalase katA 0.0045
3625 Catalase katA 0.0045
4539 Catalase katA 0.0045
4941 Catalase katB 0.0045
790 DNA polymerase subunit alpha B POLA2 0.0045
724 Interleukin-2 receptor alpha chain IL2RA 0.0045
717 Interleukin-2 receptor subunit beta IL2RB 0.0045
2178 Metabotropic glutamate receptor 5 GRM5 0.0045
571 Melatonin receptor type 1A MTNR1A 0.0044
362 Melatonin receptor type 1B MTNR1B 0.0044
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0043
6432 Transporter snf 0.0042
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0042
183 Vascular endothelial growth factor A VEGFA 0.0042
6130 Carbonic anhydrase 13 CA13 0.0042
2112 Toll-like receptor 9 TLR9 0.0042
162 Retinoic acid receptor gamma-1 RARG 0.0041
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0041
3007 Carbonic anhydrase 12 CA12 0.0041
4205 Carbonic anhydrase 9 CA9 0.0041
54 Prothrombin F2 0.0041
3997 Cytochrome P450 24A1, mitochondrial CYP24A1 0.0041
517 Alcohol dehydrogenase 1C ADH1C 0.004
558 Solute carrier family 12 member 1 SLC12A1 0.0039
634 Squalene monooxygenase SQLE 0.0039
7196 Squalene monooxygenase ERG1 0.0039
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0039
1129 C-C chemokine receptor type 5 CCR5 0.0039
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0038
3937 Fatty-acid amide hydrolase FAAH 0.0038
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0038
6044 Serum paraoxonase/lactonase 3 PON3 0.0038
85 Growth hormone receptor GHR 0.0038
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0037
1525 Heparin-binding growth factor 2 FGF2 0.0037
563 Thyroid peroxidase TPO 0.0037
1638 Solute carrier family 2, facilitated glucose transporter member 2 SLC2A2 0.0037
2283 Steroid Delta-isomerase ksi 0.0037
2920 Steroid Delta-isomerase ksi 0.0037
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0037
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0037
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0037
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0037
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0037
390 Adenosine A3 receptor ADORA3 0.0037
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0036
4192 DNA topoisomerase 2-beta TOP2B 0.0036
633 Penicillin-binding proteins 1A/1B pbpA 0.0036
3404 Exotoxin A eta 0.0036
581 Cytochrome P450 2R1 CYP2R1 0.0035
65 Matrix metalloproteinase-9 Not Available 0.0035
185 Vasopressin V1a receptor AVPR1A 0.0035
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0035
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0035
572 Integrin alpha-L ITGAL 0.0035
5787 Angiopoietin-1 receptor TEK 0.0035
939 50S ribosomal protein L3 rplC 0.0035
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0034
322 Vasopressin V2 receptor AVPR2 0.0034
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0034
267 Plasminogen activator inhibitor 1 SERPINE1 0.0034
6043 Putative G-protein coupled receptor 44 GPR44 0.0034
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0034
3856 Fibroblast growth factor receptor 3 FGFR3 0.0034
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0034
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0034
780 Retinoic acid receptor RXR-gamma RXRG 0.0033
5880 Thrombopoietin receptor MPL 0.0033
908 Glutathione S-transferase theta-1 GSTT1 0.0033
6048 Troponin C, skeletal muscle TNNC2 0.0032
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0032
719 Retinoic acid receptor responder protein 1 RARRES1 0.0032
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0032
1770 Phospholipase C PLCL1 0.0032
2841 Phospholipase C plc 0.0032
770 Retinoic acid-induced protein 3 GPRC5A 0.0032
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0032
6766 O-GlcNAcase BT_4395 BT_4395 0.0031
140 30S ribosomal protein S9 rpsI 0.0031
6719 30S ribosomal protein S9 rpsI 0.0031
6725 30S ribosomal protein S9 rpsI 0.0031
473 L-lactate dehydrogenase A chain LDHA 0.0031
1648 Elastin ELN 0.0031
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0031
5934 Cytochrome P450 26A1 CYP26A1 0.0031
6221 Steroid hormone receptor ERR1 ESRRA 0.003
2578 Tubulin beta-3 chain TUBB3 0.003
1353 DNA topoisomerase 1 TOP1 0.003
3552 DNA topoisomerase 1 topA 0.003
2285 Streptogramin A acetyltransferase vatD 0.003
6146 High affinity copper uptake protein 1 SLC31A1 0.003
1629 Transcription factor AP-1 JUN 0.003
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0029
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0029
2290 ADP-ribosyl cyclase 2 BST1 0.0028
24 Thymidylate synthase TMP1 0.0028
359 Thymidylate synthase TYMS 0.0028
2626 Thymidylate synthase thyA 0.0028
2729 Thymidylate synthase thyA 0.0028
5352 Thymidylate synthase THYA 0.0028
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0028
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0028
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0028
330 Spermidine synthase SRM 0.0028
3038 Spermidine synthase speE 0.0028
2298 Cytochrome P450-cam camC 0.0028
569 Retinal dehydrogenase 2 ALDH1A2 0.0028
1650 Heme carrier protein 1 SLC46A1 0.0027
4173 Tyrosine-protein kinase JAK2 JAK2 0.0027
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0027
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0027
1864 RET proto-oncogene RET 0.0027
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0027
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0027
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0027
751 Potassium channel subfamily K member 6 KCNK6 0.0026
611 Retinal dehydrogenase 1 ALDH1A1 0.0026
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0025
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0025
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0025
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0025
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0025
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0025
6103 Arylamine N-acetyltransferase 1 NAT1 0.0025
605 Fumarate reductase flavoprotein subunit frdA 0.0025
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0025
3673 Fumarate reductase flavoprotein subunit fccA 0.0025
4912 Fumarate reductase flavoprotein subunit ifcA 0.0025
6549 Fumarate reductase flavoprotein subunit frdA 0.0025
936 Ephrin type-A receptor 2 EPHA2 0.0025
2207 Rhodopsin RHO 0.0024
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0024
334 S-adenosylmethionine synthetase isoform type-2 MAT2A 0.0024
172 Potassium channel subfamily K member 1 KCNK1 0.0024
6824 Tyrosine-protein kinase Lyn LYN 0.0024
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0024
544 Potassium voltage-gated channel subfamily E member 1 KCNE1 0.0024
6039 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A PDE11A 0.0024
1992 Vitamin D-binding protein GC 0.0024
229 Retinoic acid receptor beta RARB 0.0024
5852 Type-2 angiotensin II receptor AGTR2 0.0024
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0024
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0024
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0024
730 Retinoic acid receptor alpha RARA 0.0023
453 S-adenosylmethionine synthetase isoform type-1 MAT1A 0.0023
2216 Fibroblast growth factor receptor 4 FGFR4 0.0023
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0023
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0023
268 Adenosine A2b receptor ADORA2B 0.0022
113 S-adenosylmethionine decarboxylase proenzyme AMD1 0.0022
4103 Proteasome subunit beta type 2 PSMB2 0.0022
4102 Proteasome subunit beta type 5 PSMB5 0.0022
4101 Proteasome subunit beta type 1 PSMB1 0.0022
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0022
411 Glycine N-methyltransferase GNMT 0.0022
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0022
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0022
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0022
820 Glycine receptor subunit alpha-2 GLRA2 0.0021
2449 Tubulin alpha-3 chain TUBA1A 0.0021
298 Renin REN 0.0021
6506 Stathmin-4 STMN4 0.0021
4217 Telomerase reverse transcriptase TERT 0.0021
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0021
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0021
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0021
594 Thyroxine-binding globulin SERPINA7 0.002
6677 Myelin P2 protein PMP2 0.002
106 Cannabinoid receptor 2 CNR2 0.002
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0019
1291 cAMP response element-binding protein CREB1 0.0019
718 Folate receptor gamma FOLR3 0.0019
299 Folate receptor beta FOLR2 0.0019
2499 Tubulin beta-2C chain TUBB2C 0.0019
804 Mitochondrial folate transporter/carrier SLC25A32 0.0019
233 Potassium channel subfamily K member 2 KCNK2 0.0019
1275 Estrogen sulfotransferase SULT1E1 0.0019
164 Histamine H4 receptor HRH4 0.0019
758 Thyroid hormone receptor alpha THRA 0.0019
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0019
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0018
4210 Toll-like receptor 4 TLR4 0.0018
5998 Toll-like receptor 8 TLR8 0.0018
1262 Corticotropin-lipotropin POMC 0.0018
712 Tubulin alpha chain TUB1 0.0018
1968 ATP-sensitive inward rectifier potassium channel 12 KCNJ12 0.0018
565 Extracellular calcium-sensing receptor CASR 0.0018
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0018
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0018
683 Potassium transporter GK0582 0.0018
2981 Phospholipase A2, membrane associated PLA2G2A 0.0018
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0018
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0018
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0018
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0018
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0018
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0018
6459 Glycodelin PAEP 0.0018
4486 Phenol 2-hydroxylase component B pheA2 0.0018
4477 Dihydrolipoyl dehydrogenase lpdV 0.0018
5077 Dihydrolipoyl dehydrogenase Not Available 0.0018
5117 Dihydrolipoyl dehydrogenase lpd 0.0018
4439 Ferredoxin reductase bphA4 0.0018
5078 Amine oxidase, flavin-containing PSPTO1126 0.0018
526 Thioredoxin reductase trxB 0.0018
3767 Thioredoxin reductase trxB 0.0018
5122 Mersacidin decarboxylase mrsD 0.0017
5095 Putidaredoxin reductase camA 0.0017
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0017
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0017
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0017
5109 Outer membrane protein p64k or PM-6 m-6 0.0017
5115 FkbI fkbI 0.0017
3133 UDP-galactopyranose mutase glf 0.0017
5099 UDP-galactopyranose mutase glf 0.0017
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0017
3763 5,10-methylenetetrahydrofolate reductase metF 0.0017
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0017
5094 5,10-methylenetetrahydrofolate reductase metF 0.0017
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0017
5111 Phenylacetone monooxygenase pamO 0.0017
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0017
5083 Cryptochrome DASH cry 0.0017
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0017
5081 L-aspartate oxidase nadB 0.0017
1410 Oxidoreductase HSD17B6 0.0017
4725 Oxidoreductase Not Available 0.0017
5124 Oxidoreductase Not Available 0.0017
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0017
3102 Flavohemoprotein hmp 0.0017
4969 Flavohemoprotein hmp 0.0017
543 Penicillin-binding protein 1B mrcB 0.0017
6186 Penicillin-binding protein 1B ponB 0.0017
6822 Penicillin-binding protein 1b pbp1b 0.0017
6844 Penicillin-binding protein 1b pbp1b 0.0017
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0017
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0017
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0017
1374 Natriuretic peptides B NPPB 0.0017
159 Penicillin-binding protein 2B penA 0.0017
6121 Penicillin-binding protein 2B penA 0.0017
1827 Gap junction alpha-1 protein GJA1 0.0017
1908 Vascular cell adhesion protein 1 VCAM1 0.0017
5798 Mitogen-activated protein kinase 11 MAPK11 0.0017
293 Gamma-glutamyl hydrolase GGH 0.0017
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0017
2320 Thymidine kinase, cytosolic TK1 0.0017
346 Thyroid hormone receptor beta-1 THRB 0.0017
78 Acetyl-CoA acetyltransferase, mitochondrial ACAT1 0.0016
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0016
1360 Sphingomyelin phosphodiesterase SMPD1 0.0016
173 Toll-like receptor 7 TLR7 0.0016
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0015
3233 Bile acid receptor NR1H4 0.0015
4440 NADH peroxidase npr 0.0015
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0015
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0015
896 Glutathione S-transferase Mu 1 GSTM1 0.0015
3594 Deoxyribodipyrimidine photo-lyase phr 0.0015
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0015
5080 Deoxyribodipyrimidine photo-lyase phr 0.0015
5072 N,N-dimethylglycine oxidase dmg 0.0015
2470 Pyruvate oxidase pox5 0.0015
5073 Ferredoxin--NADP reductase petH 0.0015
5076 Ferredoxin--NADP reductase fpr 0.0015
5119 Ferredoxin--NADP reductase petH 0.0015
5121 Ferredoxin--NADP reductase fpr 0.0015
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0015
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0015
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0015
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0015
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0015
2526 NADPH-ferredoxin reductase fprA fprA 0.0015
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0015
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0015
3957 Adenosine deaminase ADA 0.0015
6218 Pannexin-1 PANX1 0.0015
6689 TraN protein traN 0.0015
6672 Destrin DSTN 0.0015
6680 Cofilin-1 CFL1 0.0015
6670 Ig kappa chain V-I region Bi Not Available 0.0015
6671 Ig heavy chain V-III region VH26 Not Available 0.0015
6688 TraF protein traF 0.0015
6404 Rhomboid protease glpG glpG 0.0015
6797 Rhomboid protease glpG glpG 0.0015
3710 Acyl-CoA thioesterase 2 tesB 0.0015
6685 Outer membrane protein II porB 0.0015
6690 BenF-like porin PFL_1329 0.0015
6681 Probable N-acetylneuraminic acid outer membrane channel protein nanC nanC 0.0015
6687 TraO protein traO 0.0015
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0015
6559 Cytochrome c oxidase subunit 2 ctaC 0.0015
6669 Cytochrome c oxidase subunit 2 ctaC 0.0015
6668 Cytochrome c oxidase subunit 1-beta ctaDII 0.0015
6679 Colicin-Ia cia 0.0015
6676 Fe(3+)-pyochelin receptor fptA 0.0015
115 Penicillin-binding protein 2 mrdA 0.0015
6069 Penicillin-binding protein 2 mrdA 0.0015
6118 Penicillin-binding protein 2 penA 0.0015
6187 Penicillin-binding protein 2 pbpA 0.0015
6686 Penicillin-binding protein 2 pbp2 0.0015
6939 Penicillin-binding protein 2 mrdA 0.0015
7163 Penicillin-binding protein 2 pbpA 0.0015
6674 Nuclear factor erythroid 2-related factor 1 NFE2L1 0.0015
327 Glutathione reductase gor 0.0015
5110 Glutathione reductase GR2 0.0015
6033 High affinity interleukin-8 receptor A CXCR1 0.0015
2021 Thrombomodulin THBD 0.0015
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0015
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0015
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0014
6149 Solute carrier family 22 member 10 SLC22A10 0.0014
126 D-lactate dehydrogenase dld 0.0014
3545 D-lactate dehydrogenase Not Available 0.0014
4510 D-lactate dehydrogenase ldhA 0.0014
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0014
1063 Signal transducer and activator of transcription 5B STAT5B 0.0014
2599 Tyrosine-protein kinase HCK HCK 0.0014
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0014
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.0014
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0014
2893 Glycine oxidase thiO 0.0014
2300 Lysozyme E 0.0014
3633 Lysozyme R 0.0014
5597 Lysozyme 17 0.0014
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0013
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0013
2567 Thymidylate synthase thyX thyX 0.0013
2823 Trypanothione reductase TPR 0.0013
2769 P-hydroxybenzoate hydroxylase pobA 0.0013
2809 P-hydroxybenzoate hydroxylase pobA 0.0013
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0013
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0013
400 Coagulation factor IX F9 0.0013
5461 Coagulation factor IX F9 0.0013
4760 Mll3241 protein mll3241 0.0013
3395 Iron(III) dicitrate transport protein fecA fecA 0.0013
6385 H subunit of photosynthetic reaction center complex puhA 0.0013
6474 Outer membrane protein W ompW 0.0013
6678 Colicin I receptor cirA 0.0013
3578 Protein crcA crcA 0.0013
6675 Colicin-E3 ceaC 0.0013
2925 Long-chain fatty acid transport protein fadL 0.0013
6480 Outer membrane usher protein papC papC 0.0013
6438 Outer membrane protein G ompG 0.0013
2447 Ammonia channel amtB 0.0013
6116 Gastric triacylglycerol lipase LIPF 0.0012
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0012
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0012
2107 Microtubule-associated protein 1A MAP1A 0.0012
2380 Monomeric sarcosine oxidase soxA 0.0012
338 DNA polymerase UL30 0.0012
379 DNA polymerase UL54 0.0012
697 DNA polymerase ORF28 0.0012
2482 DNA polymerase 43 0.0012
4104 DNA polymerase BALF5 0.0012
6645 D-amino-acid oxidase DAO 0.0012
76 Nitric-oxide synthase, brain NOS1 0.0012
6428 Light-harvesting protein B-800/850 beta chain Not Available 0.0012
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0012
6427 Light-harvesting protein B-800/850 alpha chain Not Available 0.0012
6533 Light-harvesting protein B-800/850 alpha chain A1 0.0012
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0012
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0012
1295 Fatty acid synthase FASN 0.0012
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0012
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0012
1268 Neuropeptide S receptor NPSR1 0.0012
604 Vitamin K-dependent protein Z PROZ 0.0012
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0012
6524 Protein tonB tonB 0.0012
2679 Vitamin B12 transporter btuB btuB 0.0012
5433 UPF0230 protein TM_1468 TM_1468 0.0012
5431 Lipid binding protein Not Available 0.0012
3616 Fatty acid-binding protein, epidermal FABP5 0.0012
5430 Hepatocyte nuclear factor 4-gamma HNF4G 0.0012
484 Tyrosine-protein kinase ABL2 ABL2 0.0011
754 Pancreatic triacylglycerol lipase PNLIP 0.0011
2236 Casein kinase II subunit alpha CSNK2A1 0.0011
291 Nitric-oxide synthase, endothelial NOS3 0.0011
422 Vitamin K-dependent protein C PROC 0.0011
1245 Vitamin K-dependent protein S PROS1 0.0011
6073 Potassium channel subfamily K member 9 KCNK9 0.0011
6072 Potassium channel subfamily K member 3 KCNK3 0.0011
3221 Cytochrome c4 cc4 0.0011
1810 Protein S100-A1 S100A1 0.001
6097 Protein S100-A2 S100A2 0.001
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.001
4228 Keratin, type II cytoskeletal 7 KRT7 0.001
3238 Multidrug resistance protein mexA mexA 0.001
3709 Glycerol uptake facilitator protein glpF 0.001
3116 Bacterioferritin bfr 0.001
4906 Bacterioferritin bfr 0.001
4965 Bacterioferritin bfr 0.001
5489 Ribonucleoside-diphosphate reductase 1 subunit beta nrdB 0.001
3173 Enolase eno 0.001
3336 C4-dicarboxylate transport transcriptional regulatory protein dctD dctD 0.001
3393 TGF-beta receptor type-2 TGFBR2 0.001
1144 Hepatocyte growth factor receptor MET 0.001
714 Glutathione reductase, mitochondrial GSR 0.001
493 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 0.001
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.001
283 SEC14-like protein 2 SEC14L2 0.001
1792 Tissue-type plasminogen activator PLAT 0.001
512 DNA-directed RNA polymerase alpha chain rpoA 0.001
5772 DNA-directed RNA polymerase alpha chain rpoA 0.001
4041 Microsomal glutathione S-transferase 2 MGST2 0.001
6352 Reaction center protein H chain puhA 0.001
6456 Reaction center protein H chain puhA 0.001
6682 Reaction center protein H chain puhA 0.001
6353 Reaction center protein L chain pufL 0.001
6454 Reaction center protein L chain pufL 0.001
6683 Reaction center protein L chain pufL 0.001
6354 Reaction center protein M chain pufM 0.001
6455 Reaction center protein M chain pufM 0.001
6684 Reaction center protein M chain pufM 0.001
6351 Photosynthetic reaction center cytochrome c subunit pufC 0.001
6837 Serine/threonine-protein kinase 17B STK17B 0.001
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.001
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.001
6163 Copper-transporting ATPase 2 ATP7B 0.001
6165 Copper-transporting ATPase 1 ATP7A 0.001
760 Fibroblast growth factor 1 FGF1 0.001
997 Protein kinase C beta type PRKCB 0.0009
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0009
2211 Fatty acid-binding protein, heart FABP3 0.0009
4226 Uridine phosphorylase 2 UPP2 0.0009
2828 Squalene--hopene cyclase shc 0.0009
3830 Calreticulin CALR 0.0009
459 Retinoic acid receptor RXR-alpha RXRA 0.0009
1048 Protein S100-A13 S100A13 0.0009
2226 Protein S100-A12 S100A12 0.0009
2852 DNA mismatch repair protein mutL mutL 0.0009
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0009
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0009
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0009
798 Osteocalcin BGLAP 0.0009
3191 Histidinol dehydrogenase hisD 0.0009
1970 Protein kinase C alpha type PRKCA 0.0009
6034 Hydroxyindole O-methyltransferase ASMT 0.0009
6035 Nuclear receptor ROR-beta RORB 0.0009
6036 Eosinophil peroxidase EPX 0.0009
4225 Uridine phosphorylase 1 UPP1 0.0009
2132 Protein S100-B S100B 0.0009
2408 Tyrosine-protein kinase SYK SYK 0.0009
740 Argininosuccinate synthase ASS1 0.0009
865 Argininosuccinate synthase ASS1 0.0009
2680 Argininosuccinate synthase argG 0.0009
3194 Argininosuccinate synthase argG 0.0009
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0008
22 30S ribosomal protein S4 rpsD 0.0008
6714 30S ribosomal protein S4 rpsD 0.0008
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0008
4692 A/G-specific adenine glycosylase mutY 0.0008
413 Amidophosphoribosyltransferase PPAT 0.0008
2515 Amidophosphoribosyltransferase purF 0.0008
3714 Amidophosphoribosyltransferase purF 0.0008
369 Coagulation factor VII F7 0.0008
1867 Major prion protein PRNP 0.0008
2232 Interleukin-5 IL5 0.0008
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0008
1593 Mucin-2 MUC2 0.0008
4031 Glutathione S-transferase A1 GSTA1 0.0008
6599 HTH-type transcriptional regulator ttgR ttgR 0.0008
1649 Small inducible cytokine A2 CCL2 0.0008
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0008
1025 Aquaporin-1 AQP1 0.0008
2091 Endoplasmin HSP90B1 0.0008
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0007
765 Indoleamine 2,3-dioxygenase IDO1 0.0007
461 Glycine receptor subunit alpha-3 GLRA3 0.0007
130 Prostacyclin synthase PTGIS 0.0007
2802 Endoglucanase G celCCG 0.0007
6316 ADP-ribosylation factor 1 ARF1 0.0007
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0007
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0007
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0007
6207 30S ribosomal protein S14 rpsN 0.0007
6209 30S ribosomal protein S19 rpsS 0.0007
6712 30S ribosomal protein S19 rpsS 0.0007
6726 30S ribosomal protein S19 rpsS 0.0007
645 Penicillin-binding protein 1A mrcA 0.0007
5805 Penicillin-binding protein 1A ponA 0.0007
6185 Penicillin-binding protein 1A mrcA 0.0007
6799 Penicillin-binding protein 1A pbpA 0.0007
226 Gonadotropin-releasing hormone receptor GNRHR 0.0007
1830 5'-nucleotidase NT5E 0.0007
125 DNA polymerase beta POLB 0.0007
3639 Thymidine phosphorylase deoA 0.0007
3936 Thymidine phosphorylase TYMP 0.0007
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0007
1123 Eosinophil cationic protein RNASE3 0.0007
144 Hemoglobin subunit alpha HBA1 0.0006
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0006
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0006
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0006
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.0006
6167 Organic solute transporter subunit beta OSTB 0.0006
6166 Organic solute transporter subunit alpha OSTA 0.0006
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0006
3611 Cytidine deaminase cdd 0.0006
3707 Cytidine deaminase cdd 0.0006
4211 Cytidine deaminase CDA 0.0006
1569 G1/S-specific cyclin-D1 CCND1 0.0006
1341 Histamine H3 receptor HRH3 0.0005
1760 Aminopeptidase N ANPEP 0.0005
6843 Aminopeptidase N pepN 0.0005
117 Sterol O-acyltransferase 1 SOAT1 0.0005
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0005
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0005
244 Angiotensin-converting enzyme ACE 0.0005
6211 Tubulin epsilon chain TUBE1 0.0005
6212 Tubulin gamma-1 chain TUBG1 0.0005
6210 Tubulin delta chain TUBD1 0.0005
6042 Prostaglandin reductase 2 PTGR2 0.0005
1714 Mitogen-activated protein kinase 3 MAPK3 0.0005
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0004
1176 Mitogen-activated protein kinase 1 MAPK1 0.0004
1313 Lactoylglutathione lyase GLO1 0.0004
828 Phenylalanine-4-hydroxylase PAH 0.0003
3109 Phenylalanine-4-hydroxylase phhA 0.0003
4954 Soluble cytochrome b558 Not Available 0.0003
4947 Bacterial hemoglobin vhb 0.0003
4936 Cytochrome c2 iso-2 Not Available 0.0003
4916 Cyanoglobin glbN 0.0003
4915 Cytochrome c-550 psbV 0.0003
4959 Cytochrome c-550 psbV 0.0003
5216 Cytochrome c-550 psbV 0.0003
4925 Cytochrome c-type protein SHP shp 0.0003
4943 Cytochrome c6 petJ 0.0003
4975 Cytochrome c-556 RPA3973 0.0003
4934 Cytochrome c-551 nirM 0.0003
5218 Cytochrome c-551 nirM 0.0003
4905 Cytochrome c2 Not Available 0.0003
4939 Cytochrome c2 cycA 0.0003
4964 Cytochrome c2 cycA 0.0003
4979 Cytochrome c2 cycA 0.0003
6673 Cytochrome c2 cycA 0.0003
4994 Hemoglobin-like protein HbO glbO 0.0003
4904 Cytochrome c family protein GSU1996 0.0003
4961 Hemophore HasA hasA 0.0003
4909 CooA protein cooA 0.0003
4998 Hemoglobin-like protein yjbI yjbI 0.0003
4984 Neuroglobin NGB 0.0003
5000 HemO hemO 0.0003
4942 Diheme cytochrome c napB napB 0.0003
4935 Cytochrome c-554 cycA1 0.0003
4910 Cytoglobin CYGB 0.0003
644 Heme oxygenase 2 HMOX2 0.0003
4982 Heme oxygenase 2 pbsA2 0.0003
4981 Iron-starvation protein PigA pigA 0.0003
4971 Nonaheme cytochrome c hmcA 0.0003
4989 Cytochrome c551 peroxidase ccp 0.0003
5222 Cytochrome c551 peroxidase ccpA 0.0003
4976 Apocytochrome f petA 0.0003
6407 Apocytochrome f petA 0.0003
4907 Cytochrome c-L moxG 0.0003
6865 Cytochrome c-L moxG 0.0003
4931 Cytochrome P450 167A1 CYP167A1 0.0003
4937 Cytochrome oxidase subunit II rcoxA 0.0003
4960 Putative cytochrome P450-family protein SCO7417 0.0003
4999 Cytochrome P450 165B3 CYP165B3 0.0003
4764 Cytochrome P450 165C4 CYP165C4 0.0003
4993 Hydroxylamine oxidoreductase hao1 0.0003
4926 Heme-based aerotactic transducer hemAT hemAT 0.0003
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0003
4922 Cytochrome c, putative SO_4144 0.0003
4972 P450cin cinA 0.0003
4903 Methyl-accepting chemotaxis protein Tar4 0.0003
4952 Catalase/peroxidase katA 0.0003
3093 Catalase HPII katE 0.0003
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0003
2240 Cell division protein kinase 2 CDK2 0.0003
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0003
4920 Peroxidase/catalase katG 0.0002
4948 Cytochrome c-553 Not Available 0.0002
2119 Cytochrome b5 CYB5A 0.0002
4990 PpcA ppcA 0.0002
4923 Cytochrome c3 DvMF_2499 0.0002
4945 Cytochrome c3 Not Available 0.0002
4949 Cytochrome c3 DVU_3171 0.0002
4968 Cytochrome c3 cytc3 0.0002
4997 Cytochrome c3 SO_2727 0.0002
5219 Cytochrome c3 cyd 0.0002
4902 Nine-heme cytochrome c Ddes_2038 0.0002
3189 High-molecular-weight cytochrome c hmcA 0.0002
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0002
3375 Acidic cytochrome c3 Not Available 0.0002
4988 Sulfite oxidase, mitochondrial SUOX 0.0002
2915 Sensor protein fixL fixL 0.0002
4944 Sensor protein fixL fixL 0.0002
3570 Cytochrome P450 152A1 cypC 0.0002
4385 Cytochrome c' Not Available 0.0002
4967 Cytochrome c' cycA 0.0002
5038 Cytochrome c' Not Available 0.0002
5223 Cytochrome c' cycP 0.0002
4813 Heme oxygenase hmuO 0.0002
5769 Heme oxygenase Not Available 0.0002
4037 Hypothetical protein GPX1 0.0002
4297 Hypothetical protein SP_1951 0.0002
4521 Hypothetical protein BC_2969 0.0002
4540 Hypothetical protein TM_1070 0.0002
4555 Hypothetical protein MT1739 0.0002
4569 Hypothetical protein mshD 0.0002
4578 Hypothetical protein PA3270 0.0002
4747 Hypothetical protein PA3967 0.0002
5177 Hypothetical protein TM_0096 0.0002
5194 Hypothetical protein PA1204 0.0002
5240 Hypothetical protein Rv2991 0.0002
5370 Hypothetical protein TM_1158 0.0002
5710 Hypothetical protein Tb927.5.1360 0.0002
4992 Cytochrome c peroxidase Not Available 0.0002
4289 Cytochrome P450 TT_P0059 0.0002
6262 Cytochrome P450 staP 0.0002
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0002
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0002
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0002
6168 Solute carrier family 22 member 16 SLC22A16 0.0002
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0002
3670 Soluble cytochrome b562 precursor cybC 0.0002
3411 Cytochrome P450 121 cyp121 0.0002
3291 Cytochrome c-552 cycA 0.0002
4927 Cytochrome c-552 nrfA 0.0002
4938 Cytochrome c-552 cycA 0.0002
4953 Cytochrome c-552 nrfA 0.0002
5217 Cytochrome c-552 cycM 0.0002
2617 Nitric oxide synthase oxygenase nos 0.0002
2701 Nitric oxide synthase oxygenase nos 0.0002
4386 Hemoglobin-like protein HbN glbN 0.0002
3127 Nitrite reductase nirS 0.0002
3284 Nitrite reductase nirS 0.0002
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0002
2972 6-deoxyerythronolide B hydroxylase eryF 0.0002
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0002
4608 Putative cytochrome P450 SCO1207 0.0002
4963 Putative cytochrome P450 SCO2884 0.0002
6254 Putative cytochrome P450 SCO6998 0.0002
1507 Cytochrome c CYCS 0.0002
693 Hemoglobin subunit beta HBB 0.0002
6268 Hydroxyacid oxidase 1 HAO1 0.0001
810 Heme oxygenase 1 HMOX1 0.0001
3391 Heme oxygenase 1 pbsA1 0.0001
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