DT-Web

DB00191 - Phentermine


Identification
Name Phentermine
Accession Number DB00191 (APRD00093)
Type small molecule
Description A central nervous system stimulant and sympathomimetic with actions and uses similar to those of dextroamphetamine. It has been used most frequently in the treatment of obesity. [PubChem]. Some common brand names for phentermine are Adipex-P(R) and Suprenza(TM). Phentermine is also available in combination medications such as Qsymia(R).
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 149.2328
Groups illicit
Monoisotopic Weight 149.120449485
Pharmacology
Indication For the treatment and management of obesity.
Mechanism of action Phentermine is an amphetamine that stimulates neurons to release or maintain high levels of a particular group of neurotransmitters known as catecholamines; these include dopamine and norepinephrine. High levels of these catecholamines tend to suppress hunger signals and appetite. The drug seems to inhibit reuptake of noradrenaline, dopamine, and seratonin through inhibition or reversal of the reuptake transporters. It may also inhibit MAO enzymes leaving more neurotransmitter available at the synapse.Phentermine (through catecholamine elevation) may also indirectly affect leptin levels in the brain. It is theorized that phentermine can raise levels of leptin which signal satiety. It is also theorized that increased levels of the catecholamines are partially responsible for halting another chemical messenger known as neuropeptide Y. This peptide initiates eating, decreases energy expenditure, and increases fat storage.
Absorption Phentermine is rapidly absorbed after oral ingestion.
Protein binding Approximately 96.3%
Biotransformation Hepatic.
Route of elimination Not Available
Toxicity LD50 is adult monkeys is 15 to 20 mg/kg. Symptoms of overdose include delirium, mania, self-injury, marked hypertension, tachycardia, arrhythmia, hyperpyrexia, convulsion, coma, and circulatory collapse.
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions
Drug Mechanism of interaction
Acetophenazine Decreased anorexic effect, may increase psychotic symptoms
Chlorpromazine Decreased anorexic effect, may increase psychotic symptoms
Ethopropazine Decreased anorexic effect, may increase psychotic symptoms
Fluoxetine Risk of serotoninergic syndrome
Fluphenazine Decreased anorexic effect, may increase psychotic symptoms
Fluvoxamine Risk of serotoninergic syndrome
Guanethidine Phentermine may decrease the effect of guanethidine.
Isocarboxazid Possible hypertensive crisis
Mesoridazine Decreased anorexic effect, may increase psychotic symptoms
Methdilazine Decreased anorexic effect, may increase psychotic symptoms
Methotrimeprazine Decreased anorexic effect, may increase psychotic symptoms
Paroxetine Risk of serotoninergic syndrome
Perphenazine Decreased anorexic effect, may increase psychotic symptoms
Phenelzine Possible hypertensive crisis
Prochlorperazine Decreased anorexic effect, may increase psychotic symptoms.
Promazine Decreased anorexic effect, may increase psychotic symptoms
Promethazine Decreased anorexic effect, may increase psychotic symptoms.
Propericiazine Decreased anorexic effect, may increase psychotic symptoms.
Propiomazine Decreased anorexic effect, may increase psychotic symptoms
Rasagiline Possible hypertensive crisis
Thiethylperazine Decreased anorexic effect, may increase psychotic symptoms
Thioridazine Decreased anorexic effect, may increase psychotic symptoms
Tramadol Increased risk of serotonin syndrome. Monitor for symptoms of serotonin syndrome.
Trandolapril Phentermine may reduce the efficacy of Trandolapril.
Tranylcypromine The MAO inhibitor, tranylcypromine, may increase the vasopressor effect of the amphetamine, phentermine. Concomitant therapy should be avoided.
Trifluoperazine Decreased anorexic effect, may increase psychotic symptoms
Triflupromazine Decreased anorexic effect, may increase psychotic symptoms
Trimeprazine Decreased anorexic effect, may increase psychotic symptoms
Triprolidine Triprolidine may reduce the sedative effect of the antihistamine, Phentermine.
Venlafaxine Risk of serotoninergic syndrome
Food Interactions
  • Take without regard to meals.
  • Limit caffeine intake.

Targets


Sodium-dependent noradrenaline transporter
Name Sodium-dependent noradrenaline transporter
Gene Name SLC6A2
Pharmacological action yes
Actions inhibitor
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Stephens LC, Katz SG: Phentermine and anaesthesia. Anaesth Intensive Care. 2005 Aug;33(4):525-7. - Pubmed
  • Samanin R, Garattini S: Neurochemical mechanism of action of anorectic drugs. Pharmacol Toxicol. 1993 Aug;73(2):63-8. - Pubmed
  • Proietto J, Fam BC, Ainslie DA, Thorburn AW: Novel anti-obesity drugs. Expert Opin Investig Drugs. 2000 Jun;9(6):1317-26. - Pubmed
DTHybrid score 0.6459
Sodium-dependent serotonin transporter
Name Sodium-dependent serotonin transporter
Gene Name SLC6A4
Pharmacological action yes
Actions inhibitor
References
  • John CE, Jones SR: Voltammetric characterization of the effect of monoamine uptake inhibitors and releasers on dopamine and serotonin uptake in mouse caudate-putamen and substantia nigra slices. Neuropharmacology. 2007 Jun;52(8):1596-605. Epub 2007 Mar 16. - Pubmed
  • Johnson GJ, Leis LA, Dunlop PC, Weir EK: The effect of the anorectic agent, d-fenfluramine, and its primary metabolite, d-norfenfluramine, on intact human platelet serotonin uptake and efflux. J Thromb Haemost. 2003 Dec;1(12):2663-8. - Pubmed
  • Mekontso-Dessap A, Brouri F, Pascal O, Lechat P, Hanoun N, Lanfumey L, Seif I, Benhaiem-Sigaux N, Kirsch M, Hamon M, Adnot S, Eddahibi S: Deficiency of the 5-hydroxytryptamine transporter gene leads to cardiac fibrosis and valvulopathy in mice. Circulation. 2006 Jan 3;113(1):81-9. Epub 2005 Dec 27. - Pubmed
  • Rothman RB, Ayestas MA, Dersch CM, Baumann MH: Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension. Circulation. 1999 Aug 24;100(8):869-75. - Pubmed
  • Zolkowska D, Rothman RB, Baumann MH: Amphetamine analogs increase plasma serotonin: implications for cardiac and pulmonary disease. J Pharmacol Exp Ther. 2006 Aug;318(2):604-10. Epub 2006 Apr 27. - Pubmed
DTHybrid score 0.5126
Sodium-dependent dopamine transporter
Name Sodium-dependent dopamine transporter
Gene Name SLC6A3
Pharmacological action yes
Actions inhibitor
References
  • John CE, Jones SR: Voltammetric characterization of the effect of monoamine uptake inhibitors and releasers on dopamine and serotonin uptake in mouse caudate-putamen and substantia nigra slices. Neuropharmacology. 2007 Jun;52(8):1596-605. Epub 2007 Mar 16. - Pubmed
  • Gruner JA, Marcy VR, Lin YG, Bozyczko-Coyne D, Marino MJ, Gasior M: The roles of dopamine transport inhibition and dopamine release facilitation in wake enhancement and rebound hypersomnolence induced by dopaminergic agents. Sleep. 2009 Nov 1;32(11):1425-38. - Pubmed
DTHybrid score 0.6117
Amine oxidase [flavin-containing] A
Name Amine oxidase [flavin-containing] A
Gene Name MAOA
Pharmacological action yes
Actions antagonist
References
  • Rothman RB: Is phentermine an inhibitor of monoamine oxidase? A critical appraisal. Synapse. 1999 May;32(2):141-5. - Pubmed
  • Ulus IH, Maher TJ, Wurtman RJ: Characterization of phentermine and related compounds as monoamine oxidase (MAO) inhibitors. Biochem Pharmacol. 2000 Jun 15;59(12):1611-21. - Pubmed
  • Kilpatrick IC, Traut M, Heal DJ: Monoamine oxidase inhibition is unlikely to be relevant to the risks associated with phentermine and fenfluramine: a comparison with their abilities to evoke monoamine release. Int J Obes Relat Metab Disord. 2001 Oct;25(10):1454-8. - Pubmed
  • Nandigama RK, Newton-Vinson P, Edmondson DE: Phentermine inhibition of recombinant human liver monoamine oxidases A and B. Biochem Pharmacol. 2002 Mar 1;63(5):865-9. - Pubmed
DTHybrid score 0.6418
Amine oxidase [flavin-containing] B
Name Amine oxidase [flavin-containing] B
Gene Name MAOB
Pharmacological action yes
Actions antagonist
References
  • Rothman RB: Does phentermine inhibit monoamine oxidase? Lancet. 1999 Apr 17;353(9161):1362-3. - Pubmed
  • Rothman RB: Is phentermine an inhibitor of monoamine oxidase? A critical appraisal. Synapse. 1999 May;32(2):141-5. - Pubmed
  • Ulus IH, Maher TJ, Wurtman RJ: Characterization of phentermine and related compounds as monoamine oxidase (MAO) inhibitors. Biochem Pharmacol. 2000 Jun 15;59(12):1611-21. - Pubmed
  • Kilpatrick IC, Traut M, Heal DJ: Monoamine oxidase inhibition is unlikely to be relevant to the risks associated with phentermine and fenfluramine: a comparison with their abilities to evoke monoamine release. Int J Obes Relat Metab Disord. 2001 Oct;25(10):1454-8. - Pubmed
  • Nandigama RK, Newton-Vinson P, Edmondson DE: Phentermine inhibition of recombinant human liver monoamine oxidases A and B. Biochem Pharmacol. 2002 Mar 1;63(5):865-9. - Pubmed
DTHybrid score 1.0305

Enzymes


Amine oxidase [flavin-containing] A
Name Amine oxidase [flavin-containing] A
Gene Name MAOA
Actions inhibitor
References
  • Nandigama RK, Newton-Vinson P, Edmondson DE: Phentermine inhibition of recombinant human liver monoamine oxidases A and B. Biochem Pharmacol. 2002 Mar 1;63(5):865-9. - Pubmed
  • Ulus IH, Maher TJ, Wurtman RJ: Characterization of phentermine and related compounds as monoamine oxidase (MAO) inhibitors. Biochem Pharmacol. 2000 Jun 15;59(12):1611-21. - Pubmed
DTHybrid score 0.6418
Amine oxidase [flavin-containing] B
Name Amine oxidase [flavin-containing] B
Gene Name MAOB
Actions inhibitor
References
  • Nandigama RK, Newton-Vinson P, Edmondson DE: Phentermine inhibition of recombinant human liver monoamine oxidases A and B. Biochem Pharmacol. 2002 Mar 1;63(5):865-9. - Pubmed
  • Ulus IH, Maher TJ, Wurtman RJ: Characterization of phentermine and related compounds as monoamine oxidase (MAO) inhibitors. Biochem Pharmacol. 2000 Jun 15;59(12):1611-21. - Pubmed
DTHybrid score 1.0305
Cytochrome P450 1A2
Name Cytochrome P450 1A2
Gene Name CYP1A2
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3994
Cytochrome P450 2C9
Name Cytochrome P450 2C9
Gene Name CYP2C9
Actions inhibitor,inducer
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3548
Cytochrome P450 2D6
Name Cytochrome P450 2D6
Gene Name CYP2D6
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.53

Predictions


Id Partner name Gene Name Score
4512 Cytochrome P450 3A4 CYP3A4 0.3296
6016 Cytochrome P450 2C19 CYP2C19 0.2491
1588 Multidrug resistance protein 1 ABCB1 0.1761
4924 Cytochrome P450 2C8 CYP2C8 0.1488
6030 Cytochrome P450 2B6 CYP2B6 0.1397
556 Alpha-1A adrenergic receptor ADRA1A 0.1365
131 Synaptic vesicular amine transporter SLC18A2 0.1261
6013 Cytochrome P450 2E1 CYP2E1 0.1185
4118 Cytochrome P450 3A5 CYP3A5 0.1092
492 Histamine H1 receptor HRH1 0.1077
318 Alpha-2A adrenergic receptor ADRA2A 0.1035
502 5-hydroxytryptamine 2A receptor HTR2A 0.1004
6107 Cytochrome P450 3A7 CYP3A7 0.0864
6024 Cytochrome P450 1A1 CYP1A1 0.0797
5718 Cytochrome P450 2A6 CYP2A6 0.0766
632 Alpha-1B adrenergic receptor ADRA1B 0.0762
590 5-hydroxytryptamine 2C receptor HTR2C 0.0742
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0712
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0687
193 Beta-1 adrenergic receptor ADRB1 0.0586
831 D(2) dopamine receptor DRD2 0.0571
320 5-hydroxytryptamine 1A receptor HTR1A 0.0564
20 Prostaglandin G/H synthase 1 PTGS1 0.0543
766 Beta-2 adrenergic receptor ADRB2 0.0541
587 Serum albumin ALB 0.0494
629 Alpha-2B adrenergic receptor ADRA2B 0.049
6145 Solute carrier family 22 member 1 SLC22A1 0.0462
23 D(1A) dopamine receptor DRD1 0.0458
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0457
436 5-hydroxytryptamine 2B receptor HTR2B 0.0455
6144 Solute carrier family 22 member 2 SLC22A2 0.0443
885 5-hydroxytryptamine 1B receptor HTR1B 0.0438
118 Organic cation/carnitine transporter 2 SLC22A5 0.0433
1636 Trace amine-associated receptor 1 TAAR1 0.0425
725 5-hydroxytryptamine 1D receptor HTR1D 0.0408
378 Alpha-2C adrenergic receptor ADRA2C 0.0398
6147 Solute carrier family 22 member 3 SLC22A3 0.0386
511 5-hydroxytryptamine 1F receptor HTR1F 0.0374
3810 Catechol O-methyltransferase COMT 0.0365
341 5-hydroxytryptamine 3 receptor HTR3A 0.0364
220 Sodium channel protein type 5 subunit alpha SCN5A 0.036
6106 Cytochrome P450 2C18 CYP2C18 0.0356
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0347
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0334
3811 Cytochrome P450 19A1 CYP19A1 0.0327
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0321
1656 CYP2B protein CYP2B 0.0314
789 Alpha-1D adrenergic receptor ADRA1D 0.0313
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0304
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0301
290 Prostaglandin G/H synthase 2 PTGS2 0.0298
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0293
1757 Myeloperoxidase MPO 0.0286
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0266
1729 Solute carrier family 22 member 6 SLC22A6 0.0263
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0263
36 Insulin receptor INSR 0.0258
1517 Beta-3 adrenergic receptor ADRB3 0.0249
847 Mu-type opioid receptor OPRM1 0.0244
2864 Penton protein PIII 0.0236
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0234
467 Delta-type opioid receptor OPRD1 0.0233
696 Kappa-type opioid receptor OPRK1 0.0233
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0229
3923 Cholinesterase BCHE 0.0228
146 Androgen receptor AR 0.0223
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0214
1898 Cytochrome P450 1B1 CYP1B1 0.0212
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.021
5841 Insulin-like growth factor IB IGF1 0.0206
862 Multidrug resistance-associated protein 1 ABCC1 0.0201
638 D(3) dopamine receptor DRD3 0.0193
273 Apoptosis regulator Bcl-2 BCL2 0.0192
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0188
833 Organic cation/carnitine transporter 1 SLC22A4 0.0187
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0183
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.018
474 Acetylcholinesterase ACHE 0.018
432 D(4) dopamine receptor DRD4 0.0164
817 DNA topoisomerase 2-alpha TOP2A 0.0154
6182 Cytochrome P450 2J2 CYP2J2 0.0151
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0147
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0146
6031 Cytochrome P450 3A43 CYP3A43 0.0143
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0142
465 Calmodulin CALM1 0.014
6432 Transporter snf 0.0138
163 D(1B) dopamine receptor DRD5 0.0137
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0132
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0131
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.013
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0128
891 Dihydropteroate synthase folP 0.0128
5359 Dihydropteroate synthase folP 0.0128
7175 Dihydropteroate synthase sulI 0.0128
477 DNA topoisomerase 4 subunit A parC 0.0127
886 DNA topoisomerase 4 subunit A parC 0.0127
6226 DNA topoisomerase 4 subunit A parC 0.0127
2164 Multidrug resistance-associated protein 4 ABCC4 0.0127
136 Estrogen receptor ESR1 0.0126
731 HIV-1 protease HIV-1 protease 0.0126
404 DNA gyrase subunit A gyrA 0.0125
6224 DNA gyrase subunit A gyrA 0.0125
94 5-hydroxytryptamine 4 receptor HTR4 0.0119
776 Bile salt export pump ABCB11 0.0118
6142 Solute carrier family 22 member 8 SLC22A8 0.0118
6143 Solute carrier family 22 member 7 SLC22A7 0.0116
6014 Cytochrome P450 2A13 CYP2A13 0.0113
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0113
982 Cocaine- and amphetamine-regulated transcript protein CARTPT 0.011
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.011
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.011
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0109
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0108
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0106
5698 Riboflavin synthase alpha chain ribE 0.0105
153 Dopamine beta-hydroxylase DBH 0.0102
408 Riboflavin kinase RFK 0.0101
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0101
4120 NADPH--cytochrome P450 reductase POR 0.0101
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.01
122 P2Y purinoceptor 12 P2RY12 0.01
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0097
958 Insulin-like growth factor 1 receptor IGF1R 0.0097
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0095
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0091
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.009
70 Type-1 angiotensin II receptor AGTR1 0.0089
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0088
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0086
16 Adenosine A1 receptor ADORA1 0.0084
482 Glycine receptor subunit alpha-1 GLRA1 0.0084
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0082
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0082
124 Histamine H2 receptor HRH2 0.0082
6220 Aryl hydrocarbon receptor AHR 0.0081
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0081
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0081
1178 Adenosine A2a receptor ADORA2A 0.008
3913 Glutamic acid decarboxylase GAD65 0.008
468 Cytochrome P450 4A11 CYP4A11 0.008
3917 Methylenetetrahydrofolate reductase MTHFR 0.0079
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0078
571 Melatonin receptor type 1A MTNR1A 0.0078
362 Melatonin receptor type 1B MTNR1B 0.0078
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0076
1483 Membrane copper amine oxidase AOC3 0.0076
654 Flavin reductase BLVRB 0.0075
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0074
777 Tumor necrosis factor TNF 0.0072
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0071
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0071
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.007
295 Carbonic anhydrase 1 CA1 0.0069
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0069
260 Cytochrome P450 51 ERG11 0.0068
761 Cytochrome P450 51 ERG11 0.0068
3163 Cytochrome P450 51 cyp51 0.0068
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0068
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0068
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0068
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0068
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0067
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0065
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0065
735 Alanine aminotransferase 1 GPT 0.0065
3904 Alanine aminotransferase 2 GPT2 0.0065
3947 Xanthine dehydrogenase/oxidase XDH 0.0064
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0064
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0064
904 Glutathione S-transferase P GSTP1 0.0063
2981 Phospholipase A2, membrane associated PLA2G2A 0.0063
173 Toll-like receptor 7 TLR7 0.0063
133 Dihydropterate synthase sulI 0.0063
565 Extracellular calcium-sensing receptor CASR 0.0062
4116 Dihydropteroate synthetase Not Available 0.0062
592 Carbonic anhydrase 4 CA4 0.0062
1024 Solute carrier family 22 member 11 SLC22A11 0.0062
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0062
380 Cytochrome P450 17A1 CYP17A1 0.0061
828 Phenylalanine-4-hydroxylase PAH 0.0061
3109 Phenylalanine-4-hydroxylase phhA 0.0061
365 Dihydrofolate reductase DHFR 0.006
2381 Dihydrofolate reductase DFR1 0.006
2833 Dihydrofolate reductase Not Available 0.006
2931 Dihydrofolate reductase folA 0.006
3544 Dihydrofolate reductase folA 0.006
3682 Dihydrofolate reductase folA 0.006
6642 Dihydrofolate reductase folA 0.006
6756 Dihydrofolate reductase dfrA 0.006
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.006
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.006
6126 Carbonic anhydrase 7 CA7 0.006
238 Peroxisome proliferator-activated receptor gamma PPARG 0.006
694 Matrix protein 2 M 0.0059
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0059
504 Mast/stem cell growth factor receptor KIT 0.0059
716 5-hydroxytryptamine 7 receptor HTR7 0.0058
6148 Multidrug resistance-associated protein 7 ABCC10 0.0058
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0056
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0056
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0056
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0055
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0055
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0054
6102 Arylamine N-acetyltransferase 2 NAT2 0.0053
714 Glutathione reductase, mitochondrial GSR 0.0052
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0052
174 Sigma 1-type opioid receptor SIGMAR1 0.0052
4122 Histone deacetylase 2 HDAC2 0.0052
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0051
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0051
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0051
1618 High affinity nerve growth factor receptor NTRK1 0.0051
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.005
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0049
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0049
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0049
407 Vascular endothelial growth factor receptor 2 KDR 0.0048
1256 5-hydroxytryptamine 6 receptor HTR6 0.0048
4604 Liver carboxylesterase 1 CES1 0.0048
357 Carbonic anhydrase 2 CA2 0.0048
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0047
6136 Multidrug resistance-associated protein 5 ABCC5 0.0047
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0047
6141 Sodium/bile acid cotransporter SLC10A1 0.0046
1275 Estrogen sulfotransferase SULT1E1 0.0045
992 Protein tyrosine kinase 2 beta PTK2B 0.0045
527 Prostacyclin receptor PTGIR 0.0045
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0045
319 Opioid receptor, sigma 1 OPRS1 0.0045
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0045
1360 Sphingomyelin phosphodiesterase SMPD1 0.0044
844 Epidermal growth factor receptor EGFR 0.0044
2112 Toll-like receptor 9 TLR9 0.0044
49 Endothelin B receptor EDNRB 0.0044
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0043
6137 Multidrug resistance-associated protein 6 ABCC6 0.0043
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0043
1010 Cytochrome P450 51A1 CYP51A1 0.0043
275 Arachidonate 5-lipoxygenase ALOX5 0.0042
228 Beta platelet-derived growth factor receptor PDGFRB 0.0042
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0042
756 Sex hormone-binding globulin SHBG 0.0042
6020 Aldehyde oxidase AOX1 0.0041
871 Glucocorticoid receptor NR3C1 0.0041
427 Substance-P receptor TACR1 0.0041
578 Endothelin-1 receptor EDNRA 0.0041
869 Estrogen receptor beta ESR2 0.0041
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0041
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.004
4203 Histamine N-methyltransferase HNMT 0.004
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.004
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0039
811 Translocator protein TSPO 0.0039
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0039
360 Ribonucleoside-diphosphate reductase large subunit RRM1 0.0039
26 Vascular endothelial growth factor receptor 3 FLT4 0.0039
6044 Serum paraoxonase/lactonase 3 PON3 0.0039
4209 ATP-sensitive inward rectifier potassium channel 8 KCNJ8 0.0038
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0038
6133 Sodium channel subunit beta-2 SCN2B 0.0038
6134 Sodium channel subunit beta-3 SCN3B 0.0038
6132 Sodium channel subunit beta-1 SCN1B 0.0038
6135 Sodium channel subunit beta-4 SCN4B 0.0038
6127 Carbonic anhydrase-related protein CA8 0.0038
6129 Carbonic anhydrase-related protein 11 CA11 0.0038
6128 Carbonic anhydrase-related protein 10 CA10 0.0038
605 Fumarate reductase flavoprotein subunit frdA 0.0038
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0038
3673 Fumarate reductase flavoprotein subunit fccA 0.0038
4912 Fumarate reductase flavoprotein subunit ifcA 0.0038
6549 Fumarate reductase flavoprotein subunit frdA 0.0038
1629 Transcription factor AP-1 JUN 0.0038
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0038
32 Vascular endothelial growth factor receptor 1 FLT1 0.0037
528 5-hydroxytryptamine 1E receptor HTR1E 0.0037
373 Transthyretin TTR 0.0037
130 Prostacyclin synthase PTGIS 0.0037
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0036
4228 Keratin, type II cytoskeletal 7 KRT7 0.0036
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0036
6130 Carbonic anhydrase 13 CA13 0.0036
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0036
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0035
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0035
183 Vascular endothelial growth factor A VEGFA 0.0035
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0035
5998 Toll-like receptor 8 TLR8 0.0035
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0035
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0034
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0034
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0034
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0034
712 Tubulin alpha chain TUB1 0.0034
738 Monocarboxylate transporter 1 SLC16A1 0.0034
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0034
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0034
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0033
6506 Stathmin-4 STMN4 0.0033
518 Peroxidase/catalase T katG 0.0033
327 Glutathione reductase gor 0.0033
5110 Glutathione reductase GR2 0.0033
613 Atrial natriuretic peptide receptor A NPR1 0.0033
1648 Elastin ELN 0.0032
6131 Carbonic anhydrase 14 CA14 0.0032
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0032
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0032
161 Tubulin beta chain TUBB 0.0032
312 Tubulin beta chain TUB2 0.0032
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0032
459 Retinoic acid receptor RXR-alpha RXRA 0.0032
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0031
24 Thymidylate synthase TMP1 0.0031
359 Thymidylate synthase TYMS 0.0031
2626 Thymidylate synthase thyA 0.0031
2729 Thymidylate synthase thyA 0.0031
5352 Thymidylate synthase THYA 0.0031
1227 Cytochrome b MT-CYB 0.0031
6386 Cytochrome b petB 0.0031
6937 Cytochrome b MT-CYB 0.0031
674 Dihydroorotate dehydrogenase homolog, mitochondrial PFF0160c 0.0031
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0031
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0031
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.0031
6122 Carbonic anhydrase 3 CA3 0.0031
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0031
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0031
818 50S ribosomal protein L10 rplJ 0.003
780 Retinoic acid receptor RXR-gamma RXRG 0.003
563 Thyroid peroxidase TPO 0.003
3957 Adenosine deaminase ADA 0.003
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.003
259 Microsomal triglyceride transfer protein large subunit MTTP 0.003
117 Sterol O-acyltransferase 1 SOAT1 0.003
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.003
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0029
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0029
921 Glutamate receptor 2 GRIA2 0.0029
6085 Fatty acid-binding protein, intestinal FABP2 0.0029
54 Prothrombin F2 0.0029
634 Squalene monooxygenase SQLE 0.0029
7196 Squalene monooxygenase ERG1 0.0029
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0028
6146 High affinity copper uptake protein 1 SLC31A1 0.0028
208 DNA-directed RNA polymerase beta' chain rpoC 0.0028
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0028
614 Progesterone receptor PGR 0.0028
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0028
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0028
4205 Carbonic anhydrase 9 CA9 0.0028
3007 Carbonic anhydrase 12 CA12 0.0028
1200 AMBP protein AMBP 0.0028
3866 Serum amyloid A protein SAA1 0.0028
1932 Apolipoprotein E APOE 0.0028
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0028
88 Retinoic acid receptor RXR-beta RXRB 0.0027
1192 Sulfotransferase 1A1 SULT1A1 0.0027
2159 Quinone oxidoreductase CRYZ 0.0027
3849 Insulin-like growth factor-binding protein 7 IGFBP7 0.0027
2009 Protein NOV homolog NOV 0.0027
3847 Neuroendocrine convertase 2 PCSK2 0.0027
1949 Carboxypeptidase E CPE 0.0027
3850 Synaptotagmin-like protein 4 SYTL4 0.0027
3848 Neuroendocrine convertase 1 PCSK1 0.0027
3846 Retinoblastoma-associated protein RB1 0.0027
823 Fibroblast growth factor receptor 2 FGFR2 0.0027
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0027
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0027
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0026
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.0026
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0026
790 DNA polymerase subunit alpha B POLA2 0.0026
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0025
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0025
5880 Thrombopoietin receptor MPL 0.0025
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0025
164 Histamine H4 receptor HRH4 0.0025
1541 Metalloproteinase mmp20 0.0025
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0024
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0024
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0024
1050 Bile salt sulfotransferase SULT2A1 0.0024
3639 Thymidine phosphorylase deoA 0.0024
3936 Thymidine phosphorylase TYMP 0.0024
6070 Nischarin NISCH 0.0024
537 ATP synthase delta chain, mitochondrial ATP5D 0.0024
33 Cystine/glutamate transporter SLC7A11 0.0024
952 Dipeptidyl peptidase 4 DPP4 0.0023
550 Amiloride-sensitive sodium channel subunit delta SCNN1D 0.0023
27 Amiloride-sensitive sodium channel subunit beta SCNN1B 0.0023
552 Amiloride-sensitive sodium channel subunit gamma SCNN1G 0.0023
213 Amiloride-sensitive sodium channel subunit alpha SCNN1A 0.0023
6151 Monocarboxylate transporter 10 SLC16A10 0.0023
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0023
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0023
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0022
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0022
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0022
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0022
284 DNA-directed RNA polymerase beta chain rpoB 0.0022
5773 DNA-directed RNA polymerase beta chain rpoB 0.0022
4311 tRNA TRDMT1 0.0022
4325 tRNA trmD 0.0022
4328 tRNA trmD 0.0022
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0022
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0022
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0022
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0022
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0022
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0022
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0022
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0022
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0022
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0022
2155 Insulin-degrading enzyme IDE 0.0022
1638 Solute carrier family 2, facilitated glucose transporter member 2 SLC2A2 0.0021
1244 Low-density lipoprotein receptor-related protein 2 LRP2 0.0021
976 Platelet glycoprotein IX GP9 0.0021
1374 Natriuretic peptides B NPPB 0.0021
4103 Proteasome subunit beta type 2 PSMB2 0.0021
63 Malate dehydrogenase mdh 0.0021
2329 Malate dehydrogenase mdh 0.0021
3445 Malate dehydrogenase mdh 0.0021
4420 Malate dehydrogenase mdh 0.0021
4438 Malate dehydrogenase mdh 0.0021
4102 Proteasome subunit beta type 5 PSMB5 0.0021
4101 Proteasome subunit beta type 1 PSMB1 0.0021
1827 Gap junction alpha-1 protein GJA1 0.0021
1908 Vascular cell adhesion protein 1 VCAM1 0.0021
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0021
1820 Beta-nerve growth factor NGF 0.002
814 Ryanodine receptor 1 RYR1 0.002
3856 Fibroblast growth factor receptor 3 FGFR3 0.0019
2449 Tubulin alpha-3 chain TUBA1A 0.0019
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0019
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0019
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0019
512 DNA-directed RNA polymerase alpha chain rpoA 0.0019
5772 DNA-directed RNA polymerase alpha chain rpoA 0.0019
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0019
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0019
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0019
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0018
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0018
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0018
893 [Citrate [pro-3S]-lyase] ligase citC 0.0018
845 Pyruvate dehydrogenase [cytochrome] poxB 0.0018
705 Glutamate receptor 1 GRIA1 0.0018
543 Penicillin-binding protein 1B mrcB 0.0018
6186 Penicillin-binding protein 1B ponB 0.0018
6822 Penicillin-binding protein 1b pbp1b 0.0018
6844 Penicillin-binding protein 1b pbp1b 0.0018
6766 O-GlcNAcase BT_4395 BT_4395 0.0018
645 Penicillin-binding protein 1A mrcA 0.0018
5805 Penicillin-binding protein 1A ponA 0.0018
6185 Penicillin-binding protein 1A mrcA 0.0018
6799 Penicillin-binding protein 1A pbpA 0.0018
159 Penicillin-binding protein 2B penA 0.0018
6121 Penicillin-binding protein 2B penA 0.0018
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0018
4486 Phenol 2-hydroxylase component B pheA2 0.0018
4477 Dihydrolipoyl dehydrogenase lpdV 0.0018
5077 Dihydrolipoyl dehydrogenase Not Available 0.0018
5117 Dihydrolipoyl dehydrogenase lpd 0.0018
4439 Ferredoxin reductase bphA4 0.0018
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0018
5078 Amine oxidase, flavin-containing PSPTO1126 0.0018
526 Thioredoxin reductase trxB 0.0018
3767 Thioredoxin reductase trxB 0.0018
1341 Histamine H3 receptor HRH3 0.0018
5122 Mersacidin decarboxylase mrsD 0.0017
5095 Putidaredoxin reductase camA 0.0017
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0017
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0017
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0017
5109 Outer membrane protein p64k or PM-6 m-6 0.0017
5115 FkbI fkbI 0.0017
3133 UDP-galactopyranose mutase glf 0.0017
5099 UDP-galactopyranose mutase glf 0.0017
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0017
3763 5,10-methylenetetrahydrofolate reductase metF 0.0017
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0017
5094 5,10-methylenetetrahydrofolate reductase metF 0.0017
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0017
5111 Phenylacetone monooxygenase pamO 0.0017
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0017
5083 Cryptochrome DASH cry 0.0017
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0017
5081 L-aspartate oxidase nadB 0.0017
1410 Oxidoreductase HSD17B6 0.0017
4725 Oxidoreductase Not Available 0.0017
5124 Oxidoreductase Not Available 0.0017
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0017
268 Adenosine A2b receptor ADORA2B 0.0017
737 Mineralocorticoid receptor NR3C2 0.0017
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0017
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0017
1144 Hepatocyte growth factor receptor MET 0.0017
239 Coagulation factor X F10 0.0017
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0016
3102 Flavohemoprotein hmp 0.0016
4969 Flavohemoprotein hmp 0.0016
1830 5'-nucleotidase NT5E 0.0016
165 FL cytokine receptor FLT3 0.0016
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0016
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0016
390 Adenosine A3 receptor ADORA3 0.0016
1243 Cathepsin D CTSD 0.0016
6149 Solute carrier family 22 member 10 SLC22A10 0.0016
3830 Calreticulin CALR 0.0016
2853 14 kDa fatty acid-binding protein Not Available 0.0015
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0015
4440 NADH peroxidase npr 0.0015
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0015
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0015
3594 Deoxyribodipyrimidine photo-lyase phr 0.0015
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0015
5080 Deoxyribodipyrimidine photo-lyase phr 0.0015
1864 RET proto-oncogene RET 0.0015
5072 N,N-dimethylglycine oxidase dmg 0.0015
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0015
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0015
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0015
2470 Pyruvate oxidase pox5 0.0015
5073 Ferredoxin--NADP reductase petH 0.0015
5076 Ferredoxin--NADP reductase fpr 0.0015
5119 Ferredoxin--NADP reductase petH 0.0015
5121 Ferredoxin--NADP reductase fpr 0.0015
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0015
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0015
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0015
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0015
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0015
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0015
2268 Cholesterol oxidase choB 0.0015
2822 Cholesterol oxidase choA 0.0015
2526 NADPH-ferredoxin reductase fprA fprA 0.0015
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0015
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0015
581 Cytochrome P450 2R1 CYP2R1 0.0015
558 Solute carrier family 12 member 1 SLC12A1 0.0015
2207 Rhodopsin RHO 0.0015
6689 TraN protein traN 0.0015
6043 Putative G-protein coupled receptor 44 GPR44 0.0015
6672 Destrin DSTN 0.0015
6680 Cofilin-1 CFL1 0.0015
6670 Ig kappa chain V-I region Bi Not Available 0.0015
6671 Ig heavy chain V-III region VH26 Not Available 0.0015
2499 Tubulin beta-2C chain TUBB2C 0.0015
6688 TraF protein traF 0.0015
6404 Rhomboid protease glpG glpG 0.0015
6797 Rhomboid protease glpG glpG 0.0015
3710 Acyl-CoA thioesterase 2 tesB 0.0015
6685 Outer membrane protein II porB 0.0015
6690 BenF-like porin PFL_1329 0.0015
6681 Probable N-acetylneuraminic acid outer membrane channel protein nanC nanC 0.0015
6687 TraO protein traO 0.0015
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0015
6559 Cytochrome c oxidase subunit 2 ctaC 0.0015
6669 Cytochrome c oxidase subunit 2 ctaC 0.0015
6668 Cytochrome c oxidase subunit 1-beta ctaDII 0.0015
6679 Colicin-Ia cia 0.0015
6676 Fe(3+)-pyochelin receptor fptA 0.0015
115 Penicillin-binding protein 2 mrdA 0.0015
6069 Penicillin-binding protein 2 mrdA 0.0015
6118 Penicillin-binding protein 2 penA 0.0015
6187 Penicillin-binding protein 2 pbpA 0.0015
6686 Penicillin-binding protein 2 pbp2 0.0015
6939 Penicillin-binding protein 2 mrdA 0.0015
7163 Penicillin-binding protein 2 pbpA 0.0015
6674 Nuclear factor erythroid 2-related factor 1 NFE2L1 0.0015
6034 Hydroxyindole O-methyltransferase ASMT 0.0015
3844 HLA class II histocompatibility antigen, DQ(6) alpha chain HLA-DQA2 0.0015
6035 Nuclear receptor ROR-beta RORB 0.0015
6036 Eosinophil peroxidase EPX 0.0015
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0015
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0015
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0015
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0015
7 Nitric oxide synthase, inducible NOS2 0.0015
3611 Cytidine deaminase cdd 0.0014
3707 Cytidine deaminase cdd 0.0014
4211 Cytidine deaminase CDA 0.0014
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0014
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0014
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0014
4773 Deoxycytidine kinase DCK 0.0014
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0014
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0014
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0014
3086 Plasmepsin-2 Not Available 0.0014
126 D-lactate dehydrogenase dld 0.0014
3545 D-lactate dehydrogenase Not Available 0.0014
4510 D-lactate dehydrogenase ldhA 0.0014
1992 Vitamin D-binding protein GC 0.0014
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0014
4226 Uridine phosphorylase 2 UPP2 0.0014
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0014
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0014
5934 Cytochrome P450 26A1 CYP26A1 0.0014
2893 Glycine oxidase thiO 0.0014
2091 Endoplasmin HSP90B1 0.0014
6859 Protein S100-A4 S100A4 0.0014
908 Glutathione S-transferase theta-1 GSTT1 0.0014
4148 Serine/threonine-protein kinase mTOR MTOR 0.0014
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0014
751 Potassium channel subfamily K member 6 KCNK6 0.0014
2232 Interleukin-5 IL5 0.0014
1593 Mucin-2 MUC2 0.0014
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0013
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0013
3404 Exotoxin A eta 0.0013
2567 Thymidylate synthase thyX thyX 0.0013
1630 Integrin beta-2 ITGB2 0.0013
2823 Trypanothione reductase TPR 0.0013
2769 P-hydroxybenzoate hydroxylase pobA 0.0013
2809 P-hydroxybenzoate hydroxylase pobA 0.0013
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0013
4760 Mll3241 protein mll3241 0.0013
251 Alcohol dehydrogenase 1A ADH1A 0.0013
3395 Iron(III) dicitrate transport protein fecA fecA 0.0013
6385 H subunit of photosynthetic reaction center complex puhA 0.0013
765 Indoleamine 2,3-dioxygenase IDO1 0.0013
6474 Outer membrane protein W ompW 0.0013
6678 Colicin I receptor cirA 0.0013
3578 Protein crcA crcA 0.0013
6675 Colicin-E3 ceaC 0.0013
2925 Long-chain fatty acid transport protein fadL 0.0013
6480 Outer membrane usher protein papC papC 0.0013
6438 Outer membrane protein G ompG 0.0013
2447 Ammonia channel amtB 0.0013
4225 Uridine phosphorylase 1 UPP1 0.0013
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0013
3937 Fatty-acid amide hydrolase FAAH 0.0013
860 Nicotinamide N-methyltransferase NNMT 0.0013
5626 Nucleoside diphosphate kinase B NME2 0.0013
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0013
699 Nicotinic acid receptor 1 GPR109A 0.0013
928 Nicotinic acid receptor 2 GPR109B 0.0013
583 Nicotinate-nucleotide pyrophosphorylase [carboxylating] QPRT 0.0013
2442 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0013
2459 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0013
6103 Arylamine N-acetyltransferase 1 NAT1 0.0013
84 Nuclear receptor 0B1 NR0B1 0.0013
172 Potassium channel subfamily K member 1 KCNK1 0.0012
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0012
76 Nitric-oxide synthase, brain NOS1 0.0012
820 Glycine receptor subunit alpha-2 GLRA2 0.0012
232 Corticosteroid-binding globulin SERPINA6 0.0012
2380 Monomeric sarcosine oxidase soxA 0.0012
413 Amidophosphoribosyltransferase PPAT 0.0012
2515 Amidophosphoribosyltransferase purF 0.0012
3714 Amidophosphoribosyltransferase purF 0.0012
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0012
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0012
6645 D-amino-acid oxidase DAO 0.0012
162 Retinoic acid receptor gamma-1 RARG 0.0012
6428 Light-harvesting protein B-800/850 beta chain Not Available 0.0012
6427 Light-harvesting protein B-800/850 alpha chain Not Available 0.0012
6533 Light-harvesting protein B-800/850 alpha chain A1 0.0012
6524 Protein tonB tonB 0.0012
2679 Vitamin B12 transporter btuB btuB 0.0012
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0012
29 Tubulin beta-1 chain TUBB1 0.0012
473 L-lactate dehydrogenase A chain LDHA 0.0011
6048 Troponin C, skeletal muscle TNNC2 0.0011
444 Alcohol dehydrogenase 1B ADH1B 0.0011
6677 Myelin P2 protein PMP2 0.0011
4238 50S ribosomal protein L4 rplD 0.0011
5578 50S ribosomal protein L4 rplD 0.0011
6173 50S ribosomal protein L4 rplD 0.0011
6219 50S ribosomal protein L4 rplD 0.0011
1123 Eosinophil cationic protein RNASE3 0.0011
707 72 kDa type IV collagenase MMP2 0.0011
2183 Fatty acid-binding protein, adipocyte FABP4 0.0011
4192 DNA topoisomerase 2-beta TOP2B 0.0011
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0011
106 Cannabinoid receptor 2 CNR2 0.0011
6174 50S ribosomal protein L32 rpmF 0.0011
856 Vitamin D3 receptor VDR 0.0011
2290 ADP-ribosyl cyclase 2 BST1 0.001
1196 Complement decay-accelerating factor CD55 0.001
6033 High affinity interleukin-8 receptor A CXCR1 0.001
2300 Lysozyme E 0.001
3633 Lysozyme R 0.001
5597 Lysozyme 17 0.001
4237 50S ribosomal protein L22 rplV 0.001
3809 Estrogen-related receptor gamma ESRRG 0.001
1714 Mitogen-activated protein kinase 3 MAPK3 0.001
936 Ephrin type-A receptor 2 EPHA2 0.001
68 Cannabinoid receptor 1 CNR1 0.001
5294 Nucleoside diphosphate kinase A NME1 0.001
572 Integrin alpha-L ITGAL 0.001
3868 Calcineurin subunit B isoform 2 PPP3R2 0.001
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.001
6138 Multidrug resistance protein 3 ABCB4 0.001
144 Hemoglobin subunit alpha HBA1 0.001
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.001
517 Alcohol dehydrogenase 1C ADH1C 0.001
6352 Reaction center protein H chain puhA 0.001
6456 Reaction center protein H chain puhA 0.001
6682 Reaction center protein H chain puhA 0.001
6353 Reaction center protein L chain pufL 0.001
6454 Reaction center protein L chain pufL 0.001
6683 Reaction center protein L chain pufL 0.001
6354 Reaction center protein M chain pufM 0.001
6455 Reaction center protein M chain pufM 0.001
6684 Reaction center protein M chain pufM 0.001
6351 Photosynthetic reaction center cytochrome c subunit pufC 0.001
6163 Copper-transporting ATPase 2 ATP7B 0.001
6165 Copper-transporting ATPase 1 ATP7A 0.001
291 Nitric-oxide synthase, endothelial NOS3 0.001
760 Fibroblast growth factor 1 FGF1 0.001
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.001
1039 Histone deacetylase 9 HDAC9 0.0009
2828 Squalene--hopene cyclase shc 0.0009
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0009
229 Retinoic acid receptor beta RARB 0.0009
1064 DNA (cytosine-5)-methyltransferase 1 DNMT1 0.0009
65 Matrix metalloproteinase-9 Not Available 0.0009
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0009
1268 Neuropeptide S receptor NPSR1 0.0009
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0009
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0009
730 Retinoic acid receptor alpha RARA 0.0009
2808 Chloramphenicol acetyltransferase 3 cat3 0.0009
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0009
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0009
1262 Corticotropin-lipotropin POMC 0.0008
2236 Casein kinase II subunit alpha CSNK2A1 0.0008
3808 Dihydropteroate synthase 2 folP2 0.0008
3601 Dihydropteroate synthase 1 folP1 0.0008
3807 Dihydropteroate synthase 1 folP1 0.0008
3932 Glutathione S-transferase A2 GSTA2 0.0008
2417 Chloramphenicol acetyltransferase cat 0.0008
3278 Chloramphenicol acetyltransferase cat 0.0008
6073 Potassium channel subfamily K member 9 KCNK9 0.0008
6072 Potassium channel subfamily K member 3 KCNK3 0.0008
5787 Angiopoietin-1 receptor TEK 0.0008
2810 Dr hemagglutinin structural subunit draA 0.0008
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0008
6167 Organic solute transporter subunit beta OSTB 0.0008
6166 Organic solute transporter subunit alpha OSTA 0.0008
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0008
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0008
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0008
244 Angiotensin-converting enzyme ACE 0.0008
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0008
6212 Tubulin gamma-1 chain TUBG1 0.0008
6210 Tubulin delta chain TUBD1 0.0008
6211 Tubulin epsilon chain TUBE1 0.0008
896 Glutathione S-transferase Mu 1 GSTM1 0.0008
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0008
500 Monocarboxylate transporter 4 SLC16A3 0.0008
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0008
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0008
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0008
400 Coagulation factor IX F9 0.0008
5461 Coagulation factor IX F9 0.0008
1063 Signal transducer and activator of transcription 5B STAT5B 0.0007
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0007
866 Large neutral amino acids transporter small subunit 2 SLC7A8 0.0007
4948 Cytochrome c-553 Not Available 0.0007
4923 Cytochrome c3 DvMF_2499 0.0007
4945 Cytochrome c3 Not Available 0.0007
4949 Cytochrome c3 DVU_3171 0.0007
4968 Cytochrome c3 cytc3 0.0007
4997 Cytochrome c3 SO_2727 0.0007
5219 Cytochrome c3 cyd 0.0007
4902 Nine-heme cytochrome c Ddes_2038 0.0007
3189 High-molecular-weight cytochrome c hmcA 0.0007
822 Aldose reductase AKR1B1 0.0007
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0007
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0007
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0007
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0007
604 Vitamin K-dependent protein Z PROZ 0.0007
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0007
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0007
6228 Nuclear receptor coactivator 1 NCOA1 0.0007
469 Annexin A1 ANXA1 0.0007
6241 Nuclear receptor coactivator 2 NCOA2 0.0007
4217 Telomerase reverse transcriptase TERT 0.0007
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0006
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0006
1245 Vitamin K-dependent protein S PROS1 0.0006
422 Vitamin K-dependent protein C PROC 0.0006
4386 Hemoglobin-like protein HbN glbN 0.0006
2216 Fibroblast growth factor receptor 4 FGFR4 0.0006
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0006
484 Tyrosine-protein kinase ABL2 ABL2 0.0006
719 Retinoic acid receptor responder protein 1 RARRES1 0.0006
770 Retinoic acid-induced protein 3 GPRC5A 0.0006
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0006
3221 Cytochrome c4 cc4 0.0006
2021 Thrombomodulin THBD 0.0006
5221 Cytochrome c3, 13 kDa Not Available 0.0006
3152 Cytochrome c'' cycA 0.0006
5220 Split-Soret cytochrome c Ddes_2150 0.0006
3700 Cytochrome c-552 precursor nrfA 0.0006
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0005
5924 Microtubule-associated protein 4 MAP4 0.0005
5923 Microtubule-associated protein tau MAPT 0.0005
5798 Mitogen-activated protein kinase 11 MAPK11 0.0005
2320 Thymidine kinase, cytosolic TK1 0.0005
798 Osteocalcin BGLAP 0.0005
267 Plasminogen activator inhibitor 1 SERPINE1 0.0005
569 Retinal dehydrogenase 2 ALDH1A2 0.0005
1852 Microtubule-associated protein 2 MAP2 0.0005
611 Retinal dehydrogenase 1 ALDH1A1 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
1507 Cytochrome c CYCS 0.0005
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0005
6218 Pannexin-1 PANX1 0.0005
369 Coagulation factor VII F7 0.0005
233 Potassium channel subfamily K member 2 KCNK2 0.0005
6221 Steroid hormone receptor ERR1 ESRRA 0.0005
6824 Tyrosine-protein kinase Lyn LYN 0.0005
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0005
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0004
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0004
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0004
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0004
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0004
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0004
6042 Prostaglandin reductase 2 PTGR2 0.0004
1792 Tissue-type plasminogen activator PLAT 0.0004
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0004
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0004
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0004
6168 Solute carrier family 22 member 16 SLC22A16 0.0003
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0003
1313 Lactoylglutathione lyase GLO1 0.0003
489 Monocarboxylate transporter 2 SLC16A7 0.0003
4954 Soluble cytochrome b558 Not Available 0.0002
4916 Cyanoglobin glbN 0.0002
4934 Cytochrome c-551 nirM 0.0002
5218 Cytochrome c-551 nirM 0.0002
4947 Bacterial hemoglobin vhb 0.0002
4915 Cytochrome c-550 psbV 0.0002
4959 Cytochrome c-550 psbV 0.0002
5216 Cytochrome c-550 psbV 0.0002
4925 Cytochrome c-type protein SHP shp 0.0002
4998 Hemoglobin-like protein yjbI yjbI 0.0002
4905 Cytochrome c2 Not Available 0.0002
4939 Cytochrome c2 cycA 0.0002
4964 Cytochrome c2 cycA 0.0002
4979 Cytochrome c2 cycA 0.0002
6673 Cytochrome c2 cycA 0.0002
5000 HemO hemO 0.0002
4975 Cytochrome c-556 RPA3973 0.0002
4984 Neuroglobin NGB 0.0002
4943 Cytochrome c6 petJ 0.0002
4910 Cytoglobin CYGB 0.0002
4907 Cytochrome c-L moxG 0.0002
6865 Cytochrome c-L moxG 0.0002
4981 Iron-starvation protein PigA pigA 0.0002
4971 Nonaheme cytochrome c hmcA 0.0002
4936 Cytochrome c2 iso-2 Not Available 0.0002
4909 CooA protein cooA 0.0002
4994 Hemoglobin-like protein HbO glbO 0.0002
4935 Cytochrome c-554 cycA1 0.0002
644 Heme oxygenase 2 HMOX2 0.0002
4982 Heme oxygenase 2 pbsA2 0.0002
4942 Diheme cytochrome c napB napB 0.0002
3116 Bacterioferritin bfr 0.0002
4906 Bacterioferritin bfr 0.0002
4965 Bacterioferritin bfr 0.0002
4922 Cytochrome c, putative SO_4144 0.0002
4764 Cytochrome P450 165C4 CYP165C4 0.0002
4937 Cytochrome oxidase subunit II rcoxA 0.0002
4989 Cytochrome c551 peroxidase ccp 0.0002
5222 Cytochrome c551 peroxidase ccpA 0.0002
4961 Hemophore HasA hasA 0.0002
4976 Apocytochrome f petA 0.0002
6407 Apocytochrome f petA 0.0002
4904 Cytochrome c family protein GSU1996 0.0002
4903 Methyl-accepting chemotaxis protein Tar4 0.0002
4999 Cytochrome P450 165B3 CYP165B3 0.0002
4960 Putative cytochrome P450-family protein SCO7417 0.0002
4931 Cytochrome P450 167A1 CYP167A1 0.0002
4926 Heme-based aerotactic transducer hemAT hemAT 0.0002
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0002
4993 Hydroxylamine oxidoreductase hao1 0.0002
4972 P450cin cinA 0.0002
3093 Catalase HPII katE 0.0002
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0002
4952 Catalase/peroxidase katA 0.0002
4920 Peroxidase/catalase katG 0.0001
2119 Cytochrome b5 CYB5A 0.0001
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0001
4990 PpcA ppcA 0.0001
4988 Sulfite oxidase, mitochondrial SUOX 0.0001
3375 Acidic cytochrome c3 Not Available 0.0001
2915 Sensor protein fixL fixL 0.0001
4944 Sensor protein fixL fixL 0.0001
4037 Hypothetical protein GPX1 0.0001
4297 Hypothetical protein SP_1951 0.0001
4521 Hypothetical protein BC_2969 0.0001
4540 Hypothetical protein TM_1070 0.0001
4555 Hypothetical protein MT1739 0.0001
4569 Hypothetical protein mshD 0.0001
4578 Hypothetical protein PA3270 0.0001
4747 Hypothetical protein PA3967 0.0001
5177 Hypothetical protein TM_0096 0.0001
5194 Hypothetical protein PA1204 0.0001
5240 Hypothetical protein Rv2991 0.0001
5370 Hypothetical protein TM_1158 0.0001
5710 Hypothetical protein Tb927.5.1360 0.0001
3570 Cytochrome P450 152A1 cypC 0.0001
4385 Cytochrome c' Not Available 0.0001
4967 Cytochrome c' cycA 0.0001
5038 Cytochrome c' Not Available 0.0001
5223 Cytochrome c' cycP 0.0001
4813 Heme oxygenase hmuO 0.0001
5769 Heme oxygenase Not Available 0.0001
4992 Cytochrome c peroxidase Not Available 0.0001
4289 Cytochrome P450 TT_P0059 0.0001
6262 Cytochrome P450 staP 0.0001
2230 Catalase CAT 0.0001
3249 Catalase katA 0.0001
3625 Catalase katA 0.0001
4539 Catalase katA 0.0001
4941 Catalase katB 0.0001
3670 Soluble cytochrome b562 precursor cybC 0.0001
3411 Cytochrome P450 121 cyp121 0.0001
3291 Cytochrome c-552 cycA 0.0001
4927 Cytochrome c-552 nrfA 0.0001
4938 Cytochrome c-552 cycA 0.0001
4953 Cytochrome c-552 nrfA 0.0001
5217 Cytochrome c-552 cycM 0.0001
2617 Nitric oxide synthase oxygenase nos 0.0001
2701 Nitric oxide synthase oxygenase nos 0.0001
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0001
2972 6-deoxyerythronolide B hydroxylase eryF 0.0001
4608 Putative cytochrome P450 SCO1207 0.0001
4963 Putative cytochrome P450 SCO2884 0.0001
6254 Putative cytochrome P450 SCO6998 0.0001
358 Cystathionine beta-synthase CBS 0.0001
693 Hemoglobin subunit beta HBB 0.0001
6268 Hydroxyacid oxidase 1 HAO1 0.0001
810 Heme oxygenase 1 HMOX1 0.0001
3391 Heme oxygenase 1 pbsA1 0.0001
2298 Cytochrome P450-cam camC 0.0001
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