DT-Web

UDP-glucuronosyltransferase 3A1


Partner ID 6656
Name UDP-glucuronosyltransferase 3A1
Synonyms 8908
Gene name UGT3A1
General function Carbohydrate transport and metabolism
Specific function UDP-glucuronosyltransferases catalyze phase II biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (By similarity)
Gene sequence + ...

ATGGTTGGGCAGCGGGTGCTGCTTCTAGTGGCCTTCCTTCTTTCTGGGGTCCTGCTCTCAGAGGCTGCCAAAATCCTGACAATATCTACACTGGGTGGAAGCCATTACCTACTGTTGGACCGGGTGTCTCAGATTCTTCAAGAGCATGGTCATAATGTGACTATGCTTCATCAGAGTGGAAAGTTTTTGATCCCAGATATTAAAGAGGAGGAAAAATCATACCAAGTTATCAGGTGGTTTTCACCTGAAGATCATCAAAAAAGAATTAAGAAGCATTTTGATAGCTACATAGAAACAGCATTGGATGGCAGAAAAGAATCTGAAGCCCTTGTAAAGCTAATGGAAATATTTGGGACTCAATGTAGTTATTTGCTAAGCAGAAAGGATATAATGGATTCCTTAAAGAATGAGAACTGTGATCTGGTATTTGTTGAAGCATTTGATTTCTGTTCTTTCCTGATTGCTGAGAAGCTTGTGAAACCATTTGTGGCCATTCTTCCCACCACATTCGGCTCTTTGGATTTTGGGCTACCAAGCCCCTTGTCTTATGTTCCAGTATTCCCTTCCTTGCTGACTGATCACATGGACTTCTGGGGCCGAGTGAAGAATTTTCTGATGTTCTTTAGTTTCTCCAGGAGCCAATGGGACATGCAGTCTACATTTGACAACACCATCAAGGAGCATTTCCCAGAAGGCTCTAGGCCAGTTTTGTCTCATCTTCTACTGAAAGCAGAGTTGTGGTTTGTTAACTCTGATTTTGCCTTTGATTTTGCCCGGCCCCTGCTTCCCAACACTGTTTATATTGGAGGCTTGATGGAAAAACCTATTAAACCAGTACCACAAGACTTGGACAACTTCATTGCCAACTTTGGGGATGCAGGGTTTGTCCTTGTGGCCTTTGGCTCCATGTTGAACACCCATCAGTCCCAGGAAGTCCTCAAGAAGATGCACAATGCCTTTGCCCACCTCCCTCAAGGAGTGATATGGACATGTCAGAGTTCTCATTGGCCCAGAGATGTTCATTTGGCCACAAATGTGAAAATTGTGGACTGGCTTCCTCAGAGTGACCTCCTGGCTCACCCCAGCATCCGTCTTTTTGTCACTCATGGTGGGCAGAACAGCGTAATGGAGACCATCCGTCATGGTGTGCCCATGGTGGGATTACCAGTCAATGGAGACCAGCATGGAAACATGGTCCGAGTAGTAGCCAAAAATTATGGTGTCTCTATCCGGTTGAATCAGGTCACAGCCGACACACTGACACTTACAATGAAACAAGTCATAGAAGACAAGAGGTACAAGTCGGCAGTGGTGGCAGCCAGTGTCATCCTGCACTCTCAGCCCCTGAGCCCCGCACAGCGGCTGGTGGGCTGGATCGACCACATCCTCCAGACTGGGGGAGCGACGCACCTCAAGCCCTATGTCTTCCAGCAGCCTTGGCATGAGCAGTACCTCATTGATGTCTTTGTGTTTCTGCTGGGGCTCACTCTGGGCACTATGTGGCTTTGTGGGAAGCTGCTGGGTGTGGTGGCCAGGTGGCTGCGTGGGGCCAGGAAGGTGAAGAAGACATGA
Protein sequence + ...

MVGQRVLLLVAFLLSGVLLSEAAKILTISTLGGSHYLLLDRVSQILQEHGHNVTMLHQSGKFLIPDIKEEEKSYQVIRWFSPEDHQKRIKKHFDSYIETALDGRKESEALVKLMEIFGTQCSYLLSRKDIMDSLKNENYDLVFVEAFDFCSFLIAEKLVKPFVAILPTTFGSLDFGLPSPLSYVPVFPSLLTDHMDFWGRVKNFLMFFSFSRSQWDMQSTFDNTIKEHFPEGSRPVLSHLLLKAELWFVNSDFAFDFARPLLPNTVYIGGLMEKPIKPVPQDLDNFIANFGDAGFVLVAFGSMLNTHQSQEVLKKMHNAFAHLPQGVIWTCQSSHWPRDVHLATNVKIVDWLPQSDLLAHPSIRLFVTHGGQNSVMEAIRHGVPMVGLPVNGDQHGNMVRVVAKNYGVSIRLNQVTADTLTLTMKQVIEDKRYKSAVVAASVILHSQPLSPAQRLVGWIDHILQTGGATHLKPYAFQQPWHEQYLIDVFVFLLGLTLGTMWLCGKLLGVVARWLRGARKVKKT
GO Classification
function
catalytic activity
transferase activity
transferase activity, transferring glycosyl groups
transferase activity, transferring hexosyl groups
process
physiological process
metabolism
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB01852 Kaempherol
DB04216 Quercetin

Associated as Prediction

Id Name
DB00027 Gramicidin D
DB00067 Vasopressin
DB00091 Cyclosporine
DB00116 Tetrahydrofolic acid
DB00119 Pyruvic acid
DB00131 Adenosine monophosphate
DB00142 L-Glutamic Acid
DB00143 Glutathione
DB00158 Folic Acid
DB00169 Cholecalciferol
DB00171 Adenosine triphosphate
DB00175 Pravastatin
DB00176 Fluvoxamine
DB00184 Nicotine
DB00188 Bortezomib
DB00196 Fluconazole
DB00197 Troglitazone
DB00199 Erythromycin
DB00201 Caffeine
DB00205 Pyrimethamine
DB00206 Reserpine
DB00207 Azithromycin
DB00208 Ticlopidine
DB00213 Pantoprazole
DB00214 Torasemide
DB00215 Citalopram
DB00216 Eletriptan
DB00220 Nelfinavir
DB00224 Indinavir
DB00227 Lovastatin
DB00231 Temazepam
DB00234 Reboxetine
DB00242 Cladribine
DB00250 Dapsone
DB00252 Phenytoin
DB00255 Diethylstilbestrol
DB00257 Clotrimazole
DB00264 Metoprolol
DB00275 Olmesartan
DB00276 Amsacrine
DB00277 Theophylline
DB00279 Liothyronine
DB00281 Lidocaine
DB00285 Venlafaxine
DB00286 Conjugated Estrogens
DB00295 Morphine
DB00300 Tenofovir
DB00305 Mitomycin
DB00313 Valproic Acid
DB00316 Acetaminophen
DB00317 Gefitinib
DB00320 Dihydroergotamine
DB00321 Amitriptyline
DB00328 Indomethacin
DB00333 Methadone
DB00334 Olanzapine
DB00335 Atenolol
DB00338 Omeprazole
DB00342 Terfenadine
DB00343 Diltiazem
DB00344 Protriptyline
DB00345 Aminohippurate
DB00347 Trimethadione
DB00349 Clobazam
DB00351 Megestrol
DB00358 Mefloquine
DB00359 Sulfadiazine
DB00361 Vinorelbine
DB00363 Clozapine
DB00365 Grepafloxacin
DB00370 Mirtazapine
DB00371 Meprobamate
DB00373 Timolol
DB00381 Amlodipine
DB00382 Tacrine
DB00390 Digoxin
DB00396 Progesterone
DB00398 Sorafenib
DB00399 Zoledronate
DB00401 Nisoldipine
DB00402 Eszopiclone
DB00412 Rosiglitazone
DB00415 Ampicillin
DB00418 Secobarbital
DB00421 Spironolactone
DB00428 Streptozocin
DB00439 Cerivastatin
DB00440 Trimethoprim
DB00441 Gemcitabine
DB00443 Betamethasone
DB00444 Teniposide
DB00445 Epirubicin
DB00446 Chloramphenicol
DB00448 Lansoprazole
DB00451 Levothyroxine
DB00455 Loratadine
DB00457 Prazosin
DB00458 Imipramine
DB00468 Quinine
DB00470 Dronabinol
DB00471 Montelukast
DB00472 Fluoxetine
DB00477 Chlorpromazine
DB00480 Lenalidomide
DB00481 Raloxifene
DB00482 Celecoxib
DB00490 Buspirone
DB00495 Zidovudine
DB00501 Cimetidine
DB00502 Haloperidol
DB00503 Ritonavir
DB00508 Triflupromazine
DB00514 Dextromethorphan
DB00515 Cisplatin
DB00518 Albendazole
DB00520 Caspofungin
DB00523 Alitretinoin
DB00526 Oxaliplatin
DB00529 Foscarnet
DB00530 Erlotinib
DB00531 Cyclophosphamide
DB00532 Mephenytoin
DB00533 Rofecoxib
DB00537 Ciprofloxacin
DB00539 Toremifene
DB00541 Vincristine
DB00544 Fluorouracil
DB00549 Zafirlukast
DB00554 Piroxicam
DB00555 Lamotrigine
DB00563 Methotrexate
DB00564 Carbamazepine
DB00570 Vinblastine
DB00571 Propranolol
DB00575 Clonidine
DB00584 Enalapril
DB00585 Nizatidine
DB00586 Diclofenac
DB00590 Doxazosin
DB00602 Ivermectin
DB00603 Medroxyprogesterone
DB00604 Cisapride
DB00608 Chloroquine
DB00613 Amodiaquine
DB00617 Paramethadione
DB00619 Imatinib
DB00622 Nicardipine
DB00623 Fluphenazine
DB00624 Testosterone
DB00627 Niacin
DB00631 Clofarabine
DB00635 Prednisone
DB00637 Astemizole
DB00641 Simvastatin
DB00643 Mebendazole
DB00647 Propoxyphene
DB00650 Leucovorin
DB00654 Latanoprost
DB00655 Estrone
DB00656 Trazodone
DB00661 Verapamil
DB00665 Nilutamide
DB00669 Sumatriptan
DB00672 Chlorpropamide
DB00675 Tamoxifen
DB00678 Losartan
DB00679 Thioridazine
DB00682 Warfarin
DB00683 Midazolam
DB00688 Mycophenolate mofetil
DB00690 Flurazepam
DB00693 Fluorescein
DB00694 Daunorubicin
DB00695 Furosemide
DB00696 Ergotamine
DB00698 Nitrofurantoin
DB00701 Amprenavir
DB00704 Naltrexone
DB00705 Delavirdine
DB00709 Lamivudine
DB00715 Paroxetine
DB00717 Norethindrone
DB00722 Lisinopril
DB00726 Trimipramine
DB00731 Nateglinide
DB00734 Risperidone
DB00738 Pentamidine
DB00740 Riluzole
DB00741 Hydrocortisone
DB00742 Mannitol
DB00747 Scopolamine
DB00748 Carbinoxamine
DB00751 Epinastine
DB00755 Tretinoin
DB00758 Clopidogrel
DB00762 Irinotecan
DB00764 Mometasone
DB00770 Alprostadil
DB00773 Etoposide
DB00778 Roxithromycin
DB00780 Phenelzine
DB00783 Estradiol
DB00784 Mefenamic acid
DB00788 Naproxen
DB00790 Perindopril
DB00794 Primidone
DB00795 Sulfasalazine
DB00796 Candesartan
DB00799 Tazarotene
DB00802 Alfentanil
DB00810 Biperiden
DB00813 Fentanyl
DB00814 Meloxicam
DB00818 Propofol
DB00829 Diazepam
DB00831 Trifluoperazine
DB00834 Mifepristone
DB00835 Brompheniramine
DB00836 Loperamide
DB00845 Clofazimine
DB00850 Perphenazine
DB00857 Terbinafine
DB00860 Prednisolone
DB00863 Ranitidine
DB00864 Tacrolimus
DB00875 Flupenthixol
DB00876 Eprosartan
DB00877 Sirolimus
DB00882 Clomifene
DB00897 Triazolam
DB00907 Cocaine
DB00908 Quinidine
DB00912 Repaglinide
DB00915 Amantadine
DB00916 Metronidazole
DB00917 Dinoprostone
DB00918 Almotriptan
DB00921 Buprenorphine
DB00934 Maprotiline
DB00936 Salicyclic acid
DB00938 Salmeterol
DB00945 Acetylsalicylic acid
DB00946 Phenprocoumon
DB00950 Fexofenadine
DB00951 Isoniazid
DB00957 Norgestimate
DB00958 Carboplatin
DB00959 Methylprednisolone
DB00966 Telmisartan
DB00967 Desloratadine
DB00970 Dactinomycin
DB00972 Azelastine
DB00973 Ezetimibe
DB00975 Dipyridamole
DB00977 Ethinyl Estradiol
DB00978 Lomefloxacin
DB00997 Doxorubicin
DB01007 Tioconazole
DB01009 Ketoprofen
DB01015 Sulfamethoxazole
DB01016 Glyburide
DB01023 Felodipine
DB01026 Ketoconazole
DB01029 Irbesartan
DB01030 Topotecan
DB01032 Probenecid
DB01037 Selegiline
DB01039 Fenofibrate
DB01045 Rifampin
DB01049 Ergoloid mesylate
DB01050 Ibuprofen
DB01051 Novobiocin
DB01053 Penicillin G
DB01054 Nitrendipine
DB01062 Oxybutynin
DB01069 Promethazine
DB01072 Atazanavir
DB01076 Atorvastatin
DB01079 Tegaserod
DB01086 Benzocaine
DB01088 Iloprost
DB01094 Hesperetin
DB01095 Fluvastatin
DB01097 Leflunomide
DB01098 Rosuvastatin
DB01100 Pimozide
DB01103 Quinacrine
DB01104 Sertraline
DB01110 Miconazole
DB01115 Nifedipine
DB01118 Amiodarone
DB01124 Tolbutamide
DB01129 Rabeprazole
DB01132 Pioglitazone
DB01136 Carvedilol
DB01137 Levofloxacin
DB01138 Sulfinpyrazone
DB01142 Doxepin
DB01149 Nefazodone
DB01151 Desipramine
DB01156 Bupropion
DB01162 Terazosin
DB01165 Ofloxacin
DB01167 Itraconazole
DB01169 Arsenic trioxide
DB01174 Phenobarbital
DB01177 Idarubicin
DB01181 Ifosfamide
DB01182 Propafenone
DB01183 Naloxone
DB01184 Domperidone
DB01193 Acebutolol
DB01196 Estramustine
DB01197 Captopril
DB01198 Zopiclone
DB01200 Bromocriptine
DB01201 Rifapentine
DB01202 Levetiracetam
DB01203 Nadolol
DB01204 Mitoxantrone
DB01208 Sparfloxacin
DB01211 Clarithromycin
DB01218 Halofantrine
DB01221 Ketamine
DB01224 Quetiapine
DB01229 Paclitaxel
DB01232 Saquinavir
DB01234 Dexamethasone
DB01239 Chlorprothixene
DB01241 Gemfibrozil
DB01242 Clomipramine
DB01244 Bepridil
DB01248 Docetaxel
DB01253 Ergonovine
DB01254 Dasatinib
DB01259 Lapatinib
DB01261 Sitagliptin
DB01263 Posaconazole
DB01268 Sunitinib
DB01320 Fosphenytoin
DB01323 St. John's Wort
DB01339 Vecuronium
DB01340 Cilazapril
DB01361 Troleandomycin
DB01388 Mibefradil
DB01393 Bezafibrate
DB01394 Colchicine
DB01396 Digitoxin
DB01400 Neostigmine
DB01411 Pranlukast
DB01424 Aminophenazone
DB01435 Antipyrine
DB01440 Gamma Hydroxybutyric Acid
DB01583 Liotrix
DB01586 Ursodeoxycholic acid
DB01587 Ketazolam
DB01595 Nitrazepam
DB01601 Lopinavir
DB01645 Genistein
DB01698 Rutin
DB01754 3,4-Dihydroxy-1-Methylquinolin-2(1h)-One
DB01762 Acetoacetic Acid
DB01809 1-Ter-Butyl-3-P-Tolyl-1h-Pyrazolo[3,4-D]Pyrimidin-4-Ylamine
DB01852 Kaempherol
DB01892 Hyperforin
DB01962 Phosphonotyrosine
DB02010 Staurosporine
DB02115 Daidzin
DB02261 Platelet Activating Factor
DB02375 Myricetin
DB02587 Forskolin
DB02656 2-(4-Morpholinyl)-8-Phenyl-4h-1-Benzopyran-4-One
DB02659 Cholic Acid
DB02703 Fusidic Acid
DB02746 Phthalic Acid
DB02791 Tetraphenylphosphonium
DB02901 Dihydrotestosterone
DB03014 Heme
DB03066 D-Lactic Acid
DB03166 Acetic acid
DB03203 Sphingosine
DB03467 Naringenin
DB03496 Flavopiridol
DB03650 (3e)-3-[(4-Hydroxyphenyl)Imino]-1h-Indol-2(3h)-One
DB03777 Rbt205 Inhibitor
DB03793 Benzoic Acid
DB03796 Palmitic Acid
DB03825 Rhodamine 6g
DB03902 Oxalic Acid
DB04074 Alpha-ketoisovalerate
DB04077 Glycerol
DB04100 (1,10 Phenanthroline)-(Tri-Carbon Monoxide) Rhenium (I)
DB04216 Quercetin
DB04272 Citric Acid
DB04319 6-Deoxyglucose
DB04348 Taurocholic Acid
DB04395 Phosphoaminophosphonic Acid-Adenylate Ester
DB04398 Lactic Acid
DB04417 P-Nitrophenol
DB04522 Phosphonoserine
DB04530 S,S-(2-Hydroxyethyl)Thiocysteine
DB04540 Cholesterol
DB04552 Niflumic Acid
DB04573 Estriol
DB04630 Aldosterone
DB04690 Camptothecin
DB04715 IMIDAZOPYRIDAZIN 1
DB04769 5-QUINOXALIN-6-YLMETHYLENE-THIAZOLIDINE-2,4-DIONE
DB04789 5-methyltetrahydrofolate
DB04832 Zimelidine
DB04840 Debrisoquin
DB04855 Dronedarone
DB04868 Nilotinib
DB04877 Voacamine
DB05039 Indacaterol
DB05294 Vandetanib
DB05521 Telaprevir
DB05773 ado-trastuzumab emtansine
DB05812 Abiraterone
DB06207 Silodosin
DB06210 Eltrombopag
DB06212 Tolvaptan
DB06228 Rivaroxaban
DB06287 Temsirolimus
DB06335 Saxagliptin
DB06589 Pazopanib
DB06605 Apixaban
DB06616 Bosutinib
DB06626 Axitinib
DB06695 Dabigatran etexilate
DB06702 Fesoterodine
DB06712 Nilvadipine
DB06729 Sulfaphenazole
DB06770 Benzyl alcohol
DB06772 Cabazitaxel
DB06831 2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE
DB06836 N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)- PHENYLTHIAZOLE-2-YL)-ACETAMIDE
DB06949 N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]naphthalene-2-carbohydrazide
DB06950 4-chloro-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide
DB06978 N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]-4-methoxybenzohydrazide
DB07044 3-bromo-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide
DB07073 5,5-dimethyl-2-morpholin-4-yl-5,6-dihydro-1,3-benzothiazol-7(4H)-one
DB07097 4-tert-butyl-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide
DB07098 4-bromo-N'-[(1E)-(3,5-dibromo-2,4-dihydroxyphenyl)methylidene]benzohydrazide
DB07151 4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(5H)-one
DB07242 (4R)-7,8-dichloro-1',9-dimethyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile
DB07335 3-[4-AMINO-1-(1-METHYLETHYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL]PHENOL
DB07352 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
DB07384 1-ACETYL-2-CARBOXYPIPERIDINE
DB07394 AUROVERTIN B
DB07503 (5E)-5-[(2,2-DIFLUORO-1,3-BENZODIOXOL-5-YL)METHYLENE]-1,3-THIAZOLIDINE-2,4-DIONE
DB07524 N-phenyl-1H-pyrrolo[2,3-b]pyridin-3-amine
DB07715 3-METHYL-1,6,8-TRIHYDROXYANTHRAQUINONE
DB07810 3-(4-HYDROXYPHENYL)-1-(2,4,6-TRIHYDROXYPHENYL)PROPAN-1-ONE
DB08022 (2S)-1,3-benzothiazol-2-yl{2-[(2-pyridin-3-ylethyl)amino]pyrimidin-4-yl}ethanenitrile
DB08059 (1S,6BR,9AS,11R,11BR)-9A,11B-DIMETHYL-1-[(METHYLOXY)METHYL]-3,6,9-TRIOXO-1,6,6B,7,8,9,9A,10,11,11B-DECAHYDRO-3H-FURO[4,3,2-DE]INDENO[4,5-H][2]BENZOPYRAN-11-YL ACETATE
DB08166 (4R)-7-chloro-9-methyl-1-oxo-1,2,4,9-tetrahydrospiro[beta-carboline-3,4'-piperidine]-4-carbonitrile
DB08230 5,7-DIHYDROXY-2-(3,4,5-TRIHYDROXYPHENYL)-4H-CHROMEN-4-ONE
DB08300 1-methyl-3-naphthalen-2-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
DB08399 PICEATANNOL
DB08517 (2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-dihydro-4H-chromen-4-one
DB08607 (5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE
DB08629 N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINE
DB08705 6-(5-BROMO-2-HYDROXYPHENYL)-2-OXO-4-PHENYL-1,2-DIHYDROPYRIDINE-3-CARBONITRILE
DB08707 4-[3-(4-chlorophenyl)-2,1-benzisoxazol-5-yl]pyrimidin-2-amine
DB08708 N-cyclohexyl-3-[3-(trifluoromethyl)phenyl][1,2,4]triazolo[4,3-b]pyridazin-6-amine
DB08709 2,3-diphenyl-1H-indole-7-carboxylic acid
DB08816 Ticagrelor
DB08820 Ivacaftor
DB08827 Lomitapide
DB08828 Vismodegib
DB08860 Pitavastatin
DB08864 Rilpivirine
DB08870 BRENTUXIMAB VEDOTIN
DB08873 Boceprevir
DB08874 Fidaxomicin
DB08880 Teriflunomide
DB08881 Vemurafenib
DB08882 Linagliptin
DB08884 Gadoxetate
DB08889 Carfilzomib
DB08893 Mirabegron
DB08896 Regorafenib
DB08899 Enzalutamide
DB08901 Ponatinib
DB08906 Fluticasone furoate
DB08907 Canagliflozin
DB08910 Pomalidomide
DB08911 Trametinib
DB08912 Dabrafenib
DB08916 Afatinib
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