DT-Web

DB00338 - Omeprazole


Identification
Name Omeprazole
Accession Number DB00338 (APRD00446)
Type small molecule
Description A highly effective inhibitor of gastric acid secretion used in the therapy of stomach ulcers and Zollinger-Ellison syndrome. Omeprazole belongs to a class of antisecretory compounds, the substituted benzimidazoles, that suppress gastric acid secretion by specific inhibition of the H+/K+ ATPase enzyme system at the secretory surface of the gastric parietal cell.
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 345.416
Groups approved
Monoisotopic Weight 345.114712179
Pharmacology
Indication Omeprazole is indicated for the treatment of duodenal ulcers, benign gastric ulcers, gastroesophageal reflux disease (GERD), heartburn and other symptoms associated with GERD, erosive esophagitis, and long-term treatment of pathological hypersecretory conditions like Zollinger-Ellison syndrome, multiple endocrine adenomas, and systemic mastocytosis.
Mechanism of action Omeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal cell. By acting specifically on the proton pump, omeprazole blocks the final step in acid production, thus reducing gastric acidity.
Absorption The delayed-release capsule are enteric-coated (as omeprazole is acid-labile) so the absorption of omprazole begins once the granules leave the stomach. Absorption is rapid. Peak plasma levels occur within 0.5 - 3.5 hours. The absolute bioavailability (compared with intravenous administration) of the delayed-release capsule is 30-40% at doses of 20 - 40 mg, due to presystemic metabolism. This value increases slightly when given repeatedly. Based on a relative bioavailability study, the AUC and Cmax of PRILOSEC (omeprazole magnesium) for Delayed-Release Oral Suspension were 87% and 88% of those for PRILOSEC Delayed-Release Capsules, respectively. Interestingly, when the 40 mg delayed release capsule is given with or without applesauce, it is bioequivalent. However, when the 20 mg delayed release capsule is given with the same conditions, it is not bioequivalent. When the same capsule is given to the elderly, bioavailability increases. Omeprazole was 76% bioavailable.
Protein binding 95% bound to human plasma protein.
Biotransformation Hepatic. Omeprazole is extensively metabolized by the cytochrome P450 (CYP) enzyme system. The two primary CYP isozymes involved are CYP2C19 and CYP3A4. Metabolism is stereoselective in which the S-isomer is converted to 5'O-desmethylomeprazole via CYP2C19. CYP3A4 converts the S-isomer to 3-hydroxyomeprazole. The R-isomer is converted to 5-hydroxyomeprazole by CYP2C19. CYP3A4 converts the R-isomer to any four different metabolites: 5-hydroxyomeprazole (5-OH OME), omeprazole sulfone (OME sulfone), 5'-O-desmethylomeprazole (5'-desmethyl OME), and 3-hydroxyomeprazole (3-OH OME).
Route of elimination Urinary excretion is a primary route of excretion of omeprazole metabolites. Little, if any unchanged drug was excreted in the urine. The majority of the dose (about 77%) was eliminated in urine as at least six metabolites. Two were identified as hydroxyomeprazole and the corresponding carboxylic acid. The remainder of the dose was recovered in the feces.
Toxicity Symptoms of overdose include confusion, drowsiness, blurred vision, tachycardia, nausea, diaphoresis, flushing, headache, and dry mouth.
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions
Drug Mechanism of interaction
Alprazolam Omeprazole may increase the effect of the benzodiazepine, alprazolam.
Atazanavir This gastric pH modifier decreases the levels/effects of atazanavir
Avanafil Nineteen healthy male volunteers received a single 40 omeprazole delayed-release capsule once daily for 8 days (Days 1-8), and a single 200 mg avanafil on Day 8. Twelve hour pharmacokinetics of omeprazole on Days 7 and 8 were compared. Co-administration with avanafil resulted in an approximate 5.9% increase in AUC0-inf and 8.6% increase in Cmax of omeprazole.
Bendamustine Affects hepatic CYP1A2 metabolism, thus increasing bendamustine levels. Concentration of active metabolites may be decreased due to decreased conversion.
Cefditoren Proton pump inhibitors such as omeprazole may decrease the serum concentration of cefditoren. If possible, avoid use of cefditoren with proton pump inhibitors (PPIs). Consider alternative methods to minimize/control acid reflux (eg, diet modification) or alternative antimicrobial therapy if use of PPIs can not be avoided.
Chlordiazepoxide Omeprazole may increase the effect of the benzodiazepine, chlordiazepoxide.
Cilostazol Omeprazole increases the effect of cilostazol
Clonazepam Omeprazole may increase the effect of the benzodiazepine, clonazepam.
Clopidogrel Omeprazole may decrease serum concentrations of the active metabolite(s) of clopidogrel. Clopidogrel prescribing information recommends avoiding concurrent use with omeprazole, due to the possibility that combined use may result in decreased clopidogrel effectiveness.
Clorazepate Omeprazole may increase the effect of the benzodiazepine, clorazepate.
Cyclosporine Omeprazole increases the effect and toxicity of cyclosporine
Dasatinib Omeprazole may decrease the serum level of dasatinib.
Diazepam Omeprazole may increase the effect of the benzodiazepine, diazepam.
Disopyramide The beta-blocker increases toxicity of disopyramide
Enoxacin Omeprazole may decrease the absorption of enoxacin.
Estazolam Omeprazole may increase the effect of the benzodiazepine, estazolam.
Ethotoin Omeprazole increases the effect of hydantoin
Flurazepam Omeprazole may increase the effect of the benzodiazepine, flurazepam.
Fosphenytoin Omeprazole increases the effect of hydantoin
Halazepam Omeprazole may increase the effect of the benzodiazepine, halazepam.
Indinavir Omeprazole decreases the absorption of indinavir
Itraconazole The proton pump inhibitor, omeprazole, may decrease the absorption of itraconazole.
Ketazolam Omeprazole may increase the effect of the benzodiazepine, ketazolam.
Ketoconazole The proton pump inhibitor, omeprazole, may decrease the absorption of ketoconazole.
Mephenytoin Omeprazole increases the effect of hydantoin
Methotrexate Omeprazole increases the levels of methotrexate
Midazolam Omeprazole may increase the effect of the benzodiazepine, midazolam.
Ospemifene Moderate CYP2C19 inhibitors may increase levels of ospemifene. Monitor concomitant therapy closely.
Phenytoin Omeprazole increases the effect of hydantoin
Prazepam Omeprazole may increase the effect of the benzodiazepine, prazepam.
Quazepam Omeprazole may increase the effect of the benzodiazepine, quazepam.
Rilpivirine Proton-pump inhibitors increase gastric pH which causes a decrease in the exposure of rilpivirine thus reducing efficacy.
Roflumilast Affects CYP1A2 metabolism; decreases level or effect of roflumilast.
St. John's Wort St. John's Wort decreases the levels/effects of omeprazole
Tacrolimus Omeprazole may increase the blood concentration of Tacrolimus. Monitor for changes in the therapeutic/toxic effects of Tacrolimus if Omeprazole therapy is initiated, discontinued or altered.
Tipranavir Tipranavir, co-administered with Ritonavir, may decrease the plasma concentration of Omeprazole. Consider alternate therapy or increase the dose of Omeprazole based on the therapeutic response.
Tocilizumab Omeprazole is a CYP2C19 and CYP3A4 substrate. Exposure of omeprazole decreases following administration of tocilizumab..
Triazolam Omeprazole may increase the effect of the benzodiazepine, triazolam.
Trimipramine The strong CYP2C19 inhibitor, Omeprazole, may decrease the metabolism and clearance of Trimipramine, a CYP2C19 substrate. Consider alternate therapy or monitor for changes in therapeutic and adverse effects of Trimipramine if Omeprazole is initiated, discontinued or dose changed.
Vismodegib Vismodegib serum concentrations may be decreased by proton pump inhibitors such as omeprazole.
Voriconazole Voriconazole increases the effect and toxicity of omeprazole
Food Interactions
  • Avoid alcohol.
  • Take 30-60 minutes before meals.

Targets


Potassium-transporting ATPase alpha chain 1
Name Potassium-transporting ATPase alpha chain 1
Gene Name ATP4A
Pharmacological action yes
Actions inhibitor
References
  • Tajima A, Koizumi K, Suzuki K, Higashi N, Takahashi M, Shimada T, Terano A, Hiraishi H, Kuwayama H: Proton pump inhibitors and recurrent bleeding in peptic ulcer disease. J Gastroenterol Hepatol. 2008 Dec;23 Suppl 2:S237-41. - Pubmed
  • Shi S, Klotz U: Proton pump inhibitors: an update of their clinical use and pharmacokinetics. Eur J Clin Pharmacol. 2008 Oct;64(10):935-51. Epub 2008 Aug 5. - Pubmed
  • Kirchheiner J, Glatt S, Fuhr U, Klotz U, Meineke I, Seufferlein T, Brockmoller J: Relative potency of proton-pump inhibitors-comparison of effects on intragastric pH. Eur J Clin Pharmacol. 2009 Jan;65(1):19-31. Epub 2008 Oct 17. - Pubmed
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
DTHybrid score 0.3385

Enzymes


Cytochrome P450 2C19
Name Cytochrome P450 2C19
Gene Name CYP2C19
Actions substrate,inhibitor
References
  • Foti RS, Wahlstrom JL: CYP2C19 inhibition: the impact of substrate probe selection on in vitro inhibition profiles. Drug Metab Dispos. 2008 Mar;36(3):523-8. Epub 2007 Nov 29. - Pubmed
  • Li XQ, Andersson TB, Ahlstrom M, Weidolf L: Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. Drug Metab Dispos. 2004 Aug;32(8):821-7. - Pubmed
  • Li XQ, Weidolf L, Simonsson R, Andersson TB: Enantiomer/enantiomer interactions between the S- and R- isomers of omeprazole in human cytochrome P450 enzymes: major role of CYP2C19 and CYP3A4. J Pharmacol Exp Ther. 2005 Nov;315(2):777-87. Epub 2005 Aug 10. - Pubmed
  • Flockhart DA. - Drug Interactions: Cytochrome P450 Drug Interaction Table
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
  • Yamazaki H, Inoue K, Shaw PM, Checovich WJ, Guengerich FP, Shimada T: Different contributions of cytochrome P450 2C19 and 3A4 in the oxidation of omeprazole by human liver microsomes: effects of contents of these two forms in individual human samples. J Pharmacol Exp Ther. 1997 Nov;283(2):434-42. - Pubmed
DTHybrid score 0.6722
Cytochrome P450 3A4
Name Cytochrome P450 3A4
Gene Name CYP3A4
Actions substrate,inhibitor,inducer
References
  • Li XQ, Weidolf L, Simonsson R, Andersson TB: Enantiomer/enantiomer interactions between the S- and R- isomers of omeprazole in human cytochrome P450 enzymes: major role of CYP2C19 and CYP3A4. J Pharmacol Exp Ther. 2005 Nov;315(2):777-87. Epub 2005 Aug 10. - Pubmed
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
  • Botsch S, Gautier JC, Beaune P, Eichelbaum M, Kroemer HK: Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites. Mol Pharmacol. 1993 Jan;43(1):120-6. - Pubmed
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
  • Turpeinen M, Uusitalo J, Jalonen J, Pelkonen O: Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay. Eur J Pharm Sci. 2005 Jan;24(1):123-32. - Pubmed
DTHybrid score 0.939
Cytochrome P450 1A2
Name Cytochrome P450 1A2
Gene Name CYP1A2
Actions substrate,inhibitor,inducer
References
  • Flockhart DA. - Drug Interactions: Cytochrome P450 Drug Interaction Table
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.6701
Cytochrome P450 2C9
Name Cytochrome P450 2C9
Gene Name CYP2C9
Actions substrate,inhibitor
References
  • Zhou SF, Zhou ZW, Yang LP, Cai JP: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675. Epub 2009 Sep 1. - Pubmed
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.71
Cytochrome P450 2C18
Name Cytochrome P450 2C18
Gene Name CYP2C18
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.2681
Cytochrome P450 2C8
Name Cytochrome P450 2C8
Gene Name CYP2C8
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.53
Cytochrome P450 2D6
Name Cytochrome P450 2D6
Gene Name CYP2D6
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.6694
Cholesterol side-chain cleavage enzyme, mitochondrial
Name Cholesterol side-chain cleavage enzyme, mitochondrial
Gene Name CYP11A1
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.2174
Cytochrome P450 1A1
Name Cytochrome P450 1A1
Gene Name CYP1A1
Actions inducer
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4194
Cytochrome P450 1B1
Name Cytochrome P450 1B1
Gene Name CYP1B1
Actions inducer
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.2498

Transporters


Canalicular multispecific organic anion transporter 2
Name Canalicular multispecific organic anion transporter 2
Gene Name ABCC3
Actions inducer
References
  • Hitzl M, Klein K, Zanger UM, Fritz P, Nussler AK, Neuhaus P, Fromm MF: Influence of omeprazole on multidrug resistance protein 3 expression in human liver. J Pharmacol Exp Ther. 2003 Feb;304(2):524-30. - Pubmed
DTHybrid score 0.1605
Multidrug resistance protein 1
Name Multidrug resistance protein 1
Gene Name ABCB1
Actions inhibitor
References
  • Pauli-Magnus C, Rekersbrink S, Klotz U, Fromm MF: Interaction of omeprazole, lansoprazole and pantoprazole with P-glycoprotein. Naunyn Schmiedebergs Arch Pharmacol. 2001 Dec;364(6):551-7. - Pubmed
DTHybrid score 0.6351
ATP-binding cassette sub-family G member 2
Name ATP-binding cassette sub-family G member 2
Gene Name ABCG2
Actions inhibitor
References
  • Breedveld P, Zelcer N, Pluim D, Sonmezer O, Tibben MM, Beijnen JH, Schinkel AH, van Tellingen O, Borst P, Schellens JH: Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions. Cancer Res. 2004 Aug 15;64(16):5804-11. - Pubmed
  • Suzuki K, Doki K, Homma M, Tamaki H, Hori S, Ohtani H, Sawada Y, Kohda Y: Co-administration of proton pump inhibitors delays elimination of plasma methotrexate in high-dose methotrexate therapy. Br J Clin Pharmacol. 2009 Jan;67(1):44-9. Epub 2008 Nov 17. - Pubmed
DTHybrid score 0.3919

Predictions


Id Partner name Gene Name Score
4118 Cytochrome P450 3A5 CYP3A5 0.3372
6030 Cytochrome P450 2B6 CYP2B6 0.2851
6013 Cytochrome P450 2E1 CYP2E1 0.2556
6107 Cytochrome P450 3A7 CYP3A7 0.2444
5718 Cytochrome P450 2A6 CYP2A6 0.1949
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.1688
587 Serum albumin ALB 0.1614
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.1472
20 Prostaglandin G/H synthase 1 PTGS1 0.1435
862 Multidrug resistance-associated protein 1 ABCC1 0.1352
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.1255
3811 Cytochrome P450 19A1 CYP19A1 0.1139
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0972
1729 Solute carrier family 22 member 6 SLC22A6 0.0952
776 Bile salt export pump ABCB11 0.0935
492 Histamine H1 receptor HRH1 0.0899
6145 Solute carrier family 22 member 1 SLC22A1 0.0875
824 Sodium-dependent serotonin transporter SLC6A4 0.0854
468 Cytochrome P450 4A11 CYP4A11 0.0823
2164 Multidrug resistance-associated protein 4 ABCC4 0.0821
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0817
290 Prostaglandin G/H synthase 2 PTGS2 0.0786
6144 Solute carrier family 22 member 2 SLC22A2 0.075
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0741
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0687
136 Estrogen receptor ESR1 0.066
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0654
6142 Solute carrier family 22 member 8 SLC22A8 0.0642
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0634
831 D(2) dopamine receptor DRD2 0.0626
556 Alpha-1A adrenergic receptor ADRA1A 0.0614
502 5-hydroxytryptamine 2A receptor HTR2A 0.0614
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0589
6143 Solute carrier family 22 member 7 SLC22A7 0.0567
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.056
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0544
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0533
817 DNA topoisomerase 2-alpha TOP2A 0.0531
118 Organic cation/carnitine transporter 2 SLC22A5 0.0528
6148 Multidrug resistance-associated protein 7 ABCC10 0.0523
766 Beta-2 adrenergic receptor ADRB2 0.0519
6147 Solute carrier family 22 member 3 SLC22A3 0.0502
193 Beta-1 adrenergic receptor ADRB1 0.0492
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0489
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0481
320 5-hydroxytryptamine 1A receptor HTR1A 0.0475
871 Glucocorticoid receptor NR3C1 0.0472
318 Alpha-2A adrenergic receptor ADRA2A 0.0462
6137 Multidrug resistance-associated protein 6 ABCC6 0.0446
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0443
731 HIV-1 protease HIV-1 protease 0.0434
23 D(1A) dopamine receptor DRD1 0.0431
260 Cytochrome P450 51 ERG11 0.0431
761 Cytochrome P450 51 ERG11 0.0431
3163 Cytochrome P450 51 cyp51 0.0431
3941 Amine oxidase [flavin-containing] A MAOA 0.0426
3947 Xanthine dehydrogenase/oxidase XDH 0.0424
380 Cytochrome P450 17A1 CYP17A1 0.0423
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0414
844 Epidermal growth factor receptor EGFR 0.0407
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0404
847 Mu-type opioid receptor OPRM1 0.0404
146 Androgen receptor AR 0.0397
6031 Cytochrome P450 3A43 CYP3A43 0.0397
713 Sodium-dependent dopamine transporter SLC6A3 0.0396
590 5-hydroxytryptamine 2C receptor HTR2C 0.0396
632 Alpha-1B adrenergic receptor ADRA1B 0.0392
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0381
6141 Sodium/bile acid cotransporter SLC10A1 0.0369
465 Calmodulin CALM1 0.0367
467 Delta-type opioid receptor OPRD1 0.0365
1024 Solute carrier family 22 member 11 SLC22A11 0.0359
341 5-hydroxytryptamine 3 receptor HTR3A 0.0348
833 Organic cation/carnitine transporter 1 SLC22A4 0.0344
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0343
756 Sex hormone-binding globulin SHBG 0.0337
6182 Cytochrome P450 2J2 CYP2J2 0.0335
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0334
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0333
6136 Multidrug resistance-associated protein 5 ABCC5 0.0333
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0332
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0329
696 Kappa-type opioid receptor OPRK1 0.0327
885 5-hydroxytryptamine 1B receptor HTR1B 0.032
3923 Cholinesterase BCHE 0.0313
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0313
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0312
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0308
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0306
504 Mast/stem cell growth factor receptor KIT 0.0299
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0293
789 Alpha-1D adrenergic receptor ADRA1D 0.0285
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0279
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0274
3939 Amine oxidase [flavin-containing] B MAOB 0.0273
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0273
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0272
606 Cytochrome P450 27, mitochondrial CYP27A1 0.027
638 D(3) dopamine receptor DRD3 0.027
725 5-hydroxytryptamine 1D receptor HTR1D 0.0269
6220 Aryl hydrocarbon receptor AHR 0.0268
1757 Myeloperoxidase MPO 0.0266
4120 NADPH--cytochrome P450 reductase POR 0.0265
6014 Cytochrome P450 2A13 CYP2A13 0.0265
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.026
36 Insulin receptor INSR 0.0258
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0256
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0256
122 P2Y purinoceptor 12 P2RY12 0.0253
629 Alpha-2B adrenergic receptor ADRA2B 0.025
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0249
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0248
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0247
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0247
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0247
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0246
24 Thymidylate synthase TMP1 0.0245
359 Thymidylate synthase TYMS 0.0245
2626 Thymidylate synthase thyA 0.0245
2729 Thymidylate synthase thyA 0.0245
5352 Thymidylate synthase THYA 0.0245
777 Tumor necrosis factor TNF 0.024
4604 Liver carboxylesterase 1 CES1 0.0236
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0235
70 Type-1 angiotensin II receptor AGTR1 0.0231
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0228
228 Beta platelet-derived growth factor receptor PDGFRB 0.0227
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0222
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0222
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0221
869 Estrogen receptor beta ESR2 0.0219
373 Transthyretin TTR 0.0218
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0215
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0215
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0214
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0213
1010 Cytochrome P450 51A1 CYP51A1 0.0211
29 Tubulin beta-1 chain TUBB1 0.021
378 Alpha-2C adrenergic receptor ADRA2C 0.0208
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0204
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0201
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0201
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0201
1178 Adenosine A2a receptor ADORA2A 0.02
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0199
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0199
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0198
477 DNA topoisomerase 4 subunit A parC 0.0198
886 DNA topoisomerase 4 subunit A parC 0.0198
6226 DNA topoisomerase 4 subunit A parC 0.0198
1353 DNA topoisomerase 1 TOP1 0.0198
3552 DNA topoisomerase 1 topA 0.0198
6167 Organic solute transporter subunit beta OSTB 0.0197
6166 Organic solute transporter subunit alpha OSTA 0.0196
16 Adenosine A1 receptor ADORA1 0.0196
404 DNA gyrase subunit A gyrA 0.0195
6224 DNA gyrase subunit A gyrA 0.0195
4203 Histamine N-methyltransferase HNMT 0.0194
4228 Keratin, type II cytoskeletal 7 KRT7 0.0194
161 Tubulin beta chain TUBB 0.0193
312 Tubulin beta chain TUB2 0.0193
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0192
117 Sterol O-acyltransferase 1 SOAT1 0.019
614 Progesterone receptor PGR 0.019
436 5-hydroxytryptamine 2B receptor HTR2B 0.0189
407 Vascular endothelial growth factor receptor 2 KDR 0.0188
891 Dihydropteroate synthase folP 0.0187
5359 Dihydropteroate synthase folP 0.0187
7175 Dihydropteroate synthase sulI 0.0187
432 D(4) dopamine receptor DRD4 0.0186
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0184
908 Glutathione S-transferase theta-1 GSTT1 0.0182
26 Vascular endothelial growth factor receptor 3 FLT4 0.0182
33 Cystine/glutamate transporter SLC7A11 0.0181
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.018
904 Glutathione S-transferase P GSTP1 0.018
738 Monocarboxylate transporter 1 SLC16A1 0.0177
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0177
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0177
6102 Arylamine N-acetyltransferase 2 NAT2 0.0176
32 Vascular endothelial growth factor receptor 1 FLT1 0.0174
6146 High affinity copper uptake protein 1 SLC31A1 0.0173
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.017
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.017
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.017
571 Melatonin receptor type 1A MTNR1A 0.0169
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0169
362 Melatonin receptor type 1B MTNR1B 0.0169
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0168
273 Apoptosis regulator Bcl-2 BCL2 0.0167
84 Nuclear receptor 0B1 NR0B1 0.0167
6085 Fatty acid-binding protein, intestinal FABP2 0.0166
124 Histamine H2 receptor HRH2 0.0166
634 Squalene monooxygenase SQLE 0.0165
7196 Squalene monooxygenase ERG1 0.0165
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0163
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0162
2539 Tubulin alpha-1 chain TUBA4A 0.0162
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0162
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0162
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0162
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0162
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0161
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0161
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0159
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0159
1192 Sulfotransferase 1A1 SULT1A1 0.0158
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0157
85 Growth hormone receptor GHR 0.0156
581 Cytochrome P450 2R1 CYP2R1 0.0154
474 Acetylcholinesterase ACHE 0.0153
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0152
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0152
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0152
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0152
3917 Methylenetetrahydrofolate reductase MTHFR 0.0151
2449 Tubulin alpha-3 chain TUBA1A 0.0148
365 Dihydrofolate reductase DHFR 0.0148
2381 Dihydrofolate reductase DFR1 0.0148
2833 Dihydrofolate reductase Not Available 0.0148
2931 Dihydrofolate reductase folA 0.0148
3544 Dihydrofolate reductase folA 0.0148
3682 Dihydrofolate reductase folA 0.0148
6642 Dihydrofolate reductase folA 0.0148
6756 Dihydrofolate reductase dfrA 0.0148
1629 Transcription factor AP-1 JUN 0.0147
469 Annexin A1 ANXA1 0.0146
1852 Microtubule-associated protein 2 MAP2 0.0146
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0144
811 Translocator protein TSPO 0.0144
2499 Tubulin beta-2C chain TUBB2C 0.0144
716 5-hydroxytryptamine 7 receptor HTR7 0.0141
4773 Deoxycytidine kinase DCK 0.014
1517 Beta-3 adrenergic receptor ADRB3 0.0137
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0134
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0133
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0133
1992 Vitamin D-binding protein GC 0.0133
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0133
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0132
856 Vitamin D3 receptor VDR 0.0131
4192 DNA topoisomerase 2-beta TOP2B 0.0131
5923 Microtubule-associated protein tau MAPT 0.0131
5924 Microtubule-associated protein 4 MAP4 0.0131
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0129
4122 Histone deacetylase 2 HDAC2 0.0129
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0129
818 50S ribosomal protein L10 rplJ 0.0128
952 Dipeptidyl peptidase 4 DPP4 0.0128
5934 Cytochrome P450 26A1 CYP26A1 0.0128
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0127
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0127
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0126
275 Arachidonate 5-lipoxygenase ALOX5 0.0125
737 Mineralocorticoid receptor NR3C2 0.0124
1650 Heme carrier protein 1 SLC46A1 0.0124
6163 Copper-transporting ATPase 2 ATP7B 0.0123
6165 Copper-transporting ATPase 1 ATP7A 0.0123
613 Atrial natriuretic peptide receptor A NPR1 0.0122
7 Nitric oxide synthase, inducible NOS2 0.0122
3810 Catechol O-methyltransferase COMT 0.0122
605 Fumarate reductase flavoprotein subunit frdA 0.0121
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0121
3673 Fumarate reductase flavoprotein subunit fccA 0.0121
4912 Fumarate reductase flavoprotein subunit ifcA 0.0121
6549 Fumarate reductase flavoprotein subunit frdA 0.0121
814 Ryanodine receptor 1 RYR1 0.0121
921 Glutamate receptor 2 GRIA2 0.0121
992 Protein tyrosine kinase 2 beta PTK2B 0.0121
94 5-hydroxytryptamine 4 receptor HTR4 0.012
163 D(1B) dopamine receptor DRD5 0.0119
360 Ribonucleoside-diphosphate reductase large subunit RRM1 0.0118
68 Cannabinoid receptor 1 CNR1 0.0118
896 Glutathione S-transferase Mu 1 GSTM1 0.0118
6174 50S ribosomal protein L32 rpmF 0.0118
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0118
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0117
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0116
293 Gamma-glutamyl hydrolase GGH 0.0116
48 Pyridoxal kinase PDXK 0.0116
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0114
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0114
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0114
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0112
3426 Glutamine synthetase glnA 0.0112
3987 Glutamine synthetase GLUL 0.0112
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0111
1656 CYP2B protein CYP2B 0.0111
823 Fibroblast growth factor receptor 2 FGFR2 0.0111
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0111
295 Carbonic anhydrase 1 CA1 0.011
183 Vascular endothelial growth factor A VEGFA 0.0109
1714 Mitogen-activated protein kinase 3 MAPK3 0.0109
2112 Toll-like receptor 9 TLR9 0.0108
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0108
3932 Glutathione S-transferase A2 GSTA2 0.0108
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0107
890 Niemann-Pick C1-like protein 1 NPC1L1 0.0107
936 Ephrin type-A receptor 2 EPHA2 0.0106
6599 HTH-type transcriptional regulator ttgR ttgR 0.0105
592 Carbonic anhydrase 4 CA4 0.0105
88 Retinoic acid receptor RXR-beta RXRB 0.0105
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0104
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0104
6149 Solute carrier family 22 member 10 SLC22A10 0.0104
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0103
232 Corticosteroid-binding globulin SERPINA6 0.0103
6020 Aldehyde oxidase AOX1 0.0103
511 5-hydroxytryptamine 1F receptor HTR1F 0.0101
6432 Transporter snf 0.0101
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0101
6043 Putative G-protein coupled receptor 44 GPR44 0.0101
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.01
1256 5-hydroxytryptamine 6 receptor HTR6 0.01
427 Substance-P receptor TACR1 0.01
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.01
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.01
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0099
528 5-hydroxytryptamine 1E receptor HTR1E 0.0099
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0098
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0097
4116 Dihydropteroate synthetase Not Available 0.0097
165 FL cytokine receptor FLT3 0.0097
958 Insulin-like growth factor 1 receptor IGF1R 0.0097
4148 Serine/threonine-protein kinase mTOR MTOR 0.0097
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0096
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0096
49 Endothelin B receptor EDNRB 0.0096
1760 Aminopeptidase N ANPEP 0.0095
6843 Aminopeptidase N pepN 0.0095
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0095
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0095
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0094
106 Cannabinoid receptor 2 CNR2 0.0094
5787 Angiopoietin-1 receptor TEK 0.0094
1569 G1/S-specific cyclin-D1 CCND1 0.0094
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0093
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0093
299 Folate receptor beta FOLR2 0.0093
718 Folate receptor gamma FOLR3 0.0092
804 Mitochondrial folate transporter/carrier SLC25A32 0.0092
780 Retinoic acid receptor RXR-gamma RXRG 0.0092
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0092
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0091
3856 Fibroblast growth factor receptor 3 FGFR3 0.0091
1063 Signal transducer and activator of transcription 5B STAT5B 0.0091
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0091
578 Endothelin-1 receptor EDNRA 0.009
4311 tRNA TRDMT1 0.0089
4325 tRNA trmD 0.0089
4328 tRNA trmD 0.0089
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0089
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0088
1618 High affinity nerve growth factor receptor NTRK1 0.0088
3937 Fatty-acid amide hydrolase FAAH 0.0088
239 Coagulation factor X F10 0.0088
3830 Calreticulin CALR 0.0088
1638 Solute carrier family 2, facilitated glucose transporter member 2 SLC2A2 0.0088
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0087
3809 Estrogen-related receptor gamma ESRRG 0.0087
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0087
461 Glycine receptor subunit alpha-3 GLRA3 0.0086
284 DNA-directed RNA polymerase beta chain rpoB 0.0086
5773 DNA-directed RNA polymerase beta chain rpoB 0.0086
3808 Dihydropteroate synthase 2 folP2 0.0085
3601 Dihydropteroate synthase 1 folP1 0.0085
3807 Dihydropteroate synthase 1 folP1 0.0085
790 DNA polymerase subunit alpha B POLA2 0.0084
4226 Uridine phosphorylase 2 UPP2 0.0083
1176 Mitogen-activated protein kinase 1 MAPK1 0.0083
4103 Proteasome subunit beta type 2 PSMB2 0.0083
4102 Proteasome subunit beta type 5 PSMB5 0.0083
4101 Proteasome subunit beta type 1 PSMB1 0.0083
2236 Casein kinase II subunit alpha CSNK2A1 0.0082
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0082
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0082
6034 Hydroxyindole O-methyltransferase ASMT 0.0081
6035 Nuclear receptor ROR-beta RORB 0.0081
6036 Eosinophil peroxidase EPX 0.0081
565 Extracellular calcium-sensing receptor CASR 0.008
2298 Cytochrome P450-cam camC 0.008
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0079
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0079
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0079
162 Retinoic acid receptor gamma-1 RARG 0.0079
1050 Bile salt sulfotransferase SULT2A1 0.0079
2981 Phospholipase A2, membrane associated PLA2G2A 0.0079
173 Toll-like receptor 7 TLR7 0.0079
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0079
357 Carbonic anhydrase 2 CA2 0.0078
3957 Adenosine deaminase ADA 0.0078
442 Envelope glycoprotein gp41 0.0078
4859 Envelope glycoprotein env 0.0078
2183 Fatty acid-binding protein, adipocyte FABP4 0.0077
268 Adenosine A2b receptor ADORA2B 0.0077
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0077
244 Angiotensin-converting enzyme ACE 0.0076
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0076
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0076
484 Tyrosine-protein kinase ABL2 ABL2 0.0076
4225 Uridine phosphorylase 1 UPP1 0.0076
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0076
518 Peroxidase/catalase T katG 0.0075
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0075
603 DNA polymerase alpha catalytic subunit POLA1 0.0074
476 RAC-alpha serine/threonine-protein kinase AKT1 0.0074
1541 Metalloproteinase mmp20 0.0074
6766 O-GlcNAcase BT_4395 BT_4395 0.0074
482 Glycine receptor subunit alpha-1 GLRA1 0.0074
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0073
4237 50S ribosomal protein L22 rplV 0.0073
3639 Thymidine phosphorylase deoA 0.0072
3936 Thymidine phosphorylase TYMP 0.0072
820 Glycine receptor subunit alpha-2 GLRA2 0.0072
1275 Estrogen sulfotransferase SULT1E1 0.0071
413 Amidophosphoribosyltransferase PPAT 0.0071
2515 Amidophosphoribosyltransferase purF 0.0071
3714 Amidophosphoribosyltransferase purF 0.0071
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0071
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0071
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0071
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0071
5300 Antigen peptide transporter 1 TAP1 0.0071
765 Indoleamine 2,3-dioxygenase IDO1 0.0071
81 Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial MCCC2 0.007
547 Propionyl-CoA carboxylase alpha chain, mitochondrial PCCA 0.007
495 Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial MCCC1 0.007
177 Biotin--protein ligase HLCS 0.007
690 Acetyl-CoA carboxylase 1 ACACA 0.007
6126 Carbonic anhydrase 7 CA7 0.007
131 Synaptic vesicular amine transporter SLC18A2 0.007
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.007
569 Retinal dehydrogenase 2 ALDH1A2 0.0069
5626 Nucleoside diphosphate kinase B NME2 0.0069
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0068
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0068
105 Sodium-dependent multivitamin transporter SLC5A6 0.0067
976 Platelet glycoprotein IX GP9 0.0067
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0067
6138 Multidrug resistance protein 3 ABCB4 0.0067
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0067
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0067
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0067
719 Retinoic acid receptor responder protein 1 RARRES1 0.0066
770 Retinoic acid-induced protein 3 GPRC5A 0.0066
6168 Solute carrier family 22 member 16 SLC22A16 0.0066
702 UMP-CMP kinase CMPK1 0.0066
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0065
611 Retinal dehydrogenase 1 ALDH1A1 0.0065
342 P protein [Includes: DNA-directed DNA polymerase P 0.0064
612 P protein [Includes: DNA-directed DNA polymerase P 0.0064
1820 Beta-nerve growth factor NGF 0.0064
164 Histamine H4 receptor HRH4 0.0064
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0063
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0063
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0063
1648 Elastin ELN 0.0063
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0063
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0063
3432 Multidrug-efflux transporter 1 regulator bmrR 0.0063
4476 Mannitol dehydrogenase mtlD 0.0063
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.0063
133 Dihydropterate synthase sulI 0.0063
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0062
6044 Serum paraoxonase/lactonase 3 PON3 0.0062
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0062
319 Opioid receptor, sigma 1 OPRS1 0.0062
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0061
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0061
3587 Gastrotropin FABP6 0.0061
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0061
176 30S ribosomal protein S10 rpsJ 0.006
6175 30S ribosomal protein S10 rpsJ 0.006
4117 Probable pyruvate-flavodoxin oxidoreductase ydbK 0.006
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.006
601 Propionyl-CoA carboxylase beta chain, mitochondrial PCCB 0.006
734 D1 dopamine receptor-interacting protein calcyon CALY 0.006
185 Vasopressin V1a receptor AVPR1A 0.006
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0059
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0059
4238 50S ribosomal protein L4 rplD 0.0058
5578 50S ribosomal protein L4 rplD 0.0058
6173 50S ribosomal protein L4 rplD 0.0058
6219 50S ribosomal protein L4 rplD 0.0058
322 Vasopressin V2 receptor AVPR2 0.0058
5880 Thrombopoietin receptor MPL 0.0058
208 DNA-directed RNA polymerase beta' chain rpoC 0.0058
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0058
685 Oxygen-insensitive NADPH nitroreductase nfsA 0.0057
6945 Oxygen-insensitive NADPH nitroreductase rdxA 0.0057
291 Nitric-oxide synthase, endothelial NOS3 0.0056
5294 Nucleoside diphosphate kinase A NME1 0.0056
771 Pyruvate carboxylase, mitochondrial PC 0.0056
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0056
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0055
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0055
6506 Stathmin-4 STMN4 0.0055
54 Prothrombin F2 0.0054
558 Solute carrier family 12 member 1 SLC12A1 0.0054
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0054
489 Monocarboxylate transporter 2 SLC16A7 0.0054
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0053
714 Glutathione reductase, mitochondrial GSR 0.0053
6218 Pannexin-1 PANX1 0.0053
5998 Toll-like receptor 8 TLR8 0.0053
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0052
6339 Ig kappa chain V-II region RPMI 6410 Not Available 0.0052
712 Tubulin alpha chain TUB1 0.0052
775 Acetyl-CoA carboxylase 2 ACACB 0.0052
174 Sigma 1-type opioid receptor SIGMAR1 0.0052
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0052
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0051
4217 Telomerase reverse transcriptase TERT 0.0051
887 DNA gyrase subunit B gyrB 0.0051
4150 DNA gyrase subunit B gyrB 0.0051
6225 DNA gyrase subunit B gyrB 0.0051
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0051
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0051
6824 Tyrosine-protein kinase Lyn LYN 0.0051
1039 Histone deacetylase 9 HDAC9 0.0051
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.005
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.005
76 Nitric-oxide synthase, brain NOS1 0.0049
563 Thyroid peroxidase TPO 0.0048
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0048
459 Retinoic acid receptor RXR-alpha RXRA 0.0048
1374 Natriuretic peptides B NPPB 0.0048
1827 Gap junction alpha-1 protein GJA1 0.0048
1908 Vascular cell adhesion protein 1 VCAM1 0.0048
1360 Sphingomyelin phosphodiesterase SMPD1 0.0047
2616 Ganglioside GM2 activator GM2A 0.0047
683 Potassium transporter GK0582 0.0047
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0046
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0046
527 Prostacyclin receptor PTGIR 0.0045
3086 Plasmepsin-2 Not Available 0.0045
517 Alcohol dehydrogenase 1C ADH1C 0.0045
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0045
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0045
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0045
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0045
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0045
153 Dopamine beta-hydroxylase DBH 0.0044
1196 Complement decay-accelerating factor CD55 0.0044
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0044
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0044
130 Prostacyclin synthase PTGIS 0.0044
2599 Tyrosine-protein kinase HCK HCK 0.0044
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0044
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0044
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0044
1483 Membrane copper amine oxidase AOC3 0.0043
2216 Fibroblast growth factor receptor 4 FGFR4 0.0043
705 Glutamate receptor 1 GRIA1 0.0043
1864 RET proto-oncogene RET 0.0042
1630 Integrin beta-2 ITGB2 0.0042
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0042
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0042
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0042
768 FK506-binding protein 1A FKBP1A 0.0042
1313 Lactoylglutathione lyase GLO1 0.0041
229 Retinoic acid receptor beta RARB 0.0041
5798 Mitogen-activated protein kinase 11 MAPK11 0.0041
5818 Folate receptor alpha FOLR1 0.0041
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0041
3997 Cytochrome P450 24A1, mitochondrial CYP24A1 0.0041
2320 Thymidine kinase, cytosolic TK1 0.004
730 Retinoic acid receptor alpha RARA 0.004
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.004
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.004
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.004
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0039
251 Alcohol dehydrogenase 1A ADH1A 0.0039
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0039
4146 Phosphatidylinositol 3-kinase regulatory subunit gamma PIK3R3 0.0039
4145 Phosphatidylinositol 3-kinase regulatory subunit beta PIK3R2 0.0039
1129 C-C chemokine receptor type 5 CCR5 0.0039
4209 ATP-sensitive inward rectifier potassium channel 8 KCNJ8 0.0038
2808 Chloramphenicol acetyltransferase 3 cat3 0.0038
6042 Prostaglandin reductase 2 PTGR2 0.0038
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0038
444 Alcohol dehydrogenase 1B ADH1B 0.0038
751 Potassium channel subfamily K member 6 KCNK6 0.0038
594 Thyroxine-binding globulin SERPINA7 0.0037
6103 Arylamine N-acetyltransferase 1 NAT1 0.0037
723 Cytosolic phospholipase A2 PLA2G4A 0.0037
760 Fibroblast growth factor 1 FGF1 0.0036
633 Penicillin-binding proteins 1A/1B pbpA 0.0036
543 Penicillin-binding protein 1B mrcB 0.0035
6186 Penicillin-binding protein 1B ponB 0.0035
6822 Penicillin-binding protein 1b pbp1b 0.0035
6844 Penicillin-binding protein 1b pbp1b 0.0035
1262 Corticotropin-lipotropin POMC 0.0035
2417 Chloramphenicol acetyltransferase cat 0.0035
3278 Chloramphenicol acetyltransferase cat 0.0035
2300 Lysozyme E 0.0035
3633 Lysozyme R 0.0035
5597 Lysozyme 17 0.0035
6837 Serine/threonine-protein kinase 17B STK17B 0.0035
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.0035
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0035
2810 Dr hemagglutinin structural subunit draA 0.0035
172 Potassium channel subfamily K member 1 KCNK1 0.0035
159 Penicillin-binding protein 2B penA 0.0035
6121 Penicillin-binding protein 2B penA 0.0035
939 50S ribosomal protein L3 rplC 0.0035
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0034
758 Thyroid hormone receptor alpha THRA 0.0034
267 Plasminogen activator inhibitor 1 SERPINE1 0.0034
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0034
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0033
1281 Phosphatidylinositol 3-kinase regulatory subunit alpha PIK3R1 0.0033
537 ATP synthase delta chain, mitochondrial ATP5D 0.0033
65 Matrix metalloproteinase-9 Not Available 0.0033
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0032
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0032
572 Integrin alpha-L ITGAL 0.0032
2107 Microtubule-associated protein 1A MAP1A 0.0032
140 30S ribosomal protein S9 rpsI 0.0031
6719 30S ribosomal protein S9 rpsI 0.0031
6725 30S ribosomal protein S9 rpsI 0.0031
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0031
1636 Trace amine-associated receptor 1 TAAR1 0.0031
1227 Cytochrome b MT-CYB 0.0031
6386 Cytochrome b petB 0.0031
6937 Cytochrome b MT-CYB 0.0031
674 Dihydroorotate dehydrogenase homolog, mitochondrial PFF0160c 0.0031
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0031
6221 Steroid hormone receptor ERR1 ESRRA 0.0031
346 Thyroid hormone receptor beta-1 THRB 0.0031
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0031
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0031
2578 Tubulin beta-3 chain TUBB3 0.003
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.003
6228 Nuclear receptor coactivator 1 NCOA1 0.003
2285 Streptogramin A acetyltransferase vatD 0.003
6241 Nuclear receptor coactivator 2 NCOA2 0.003
3611 Cytidine deaminase cdd 0.003
3707 Cytidine deaminase cdd 0.003
4211 Cytidine deaminase CDA 0.003
3950 Cell division protein kinase 9 CDK9 0.0029
3968 Cell division protein kinase 8 CDK8 0.0029
6048 Troponin C, skeletal muscle TNNC2 0.0029
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0029
512 DNA-directed RNA polymerase alpha chain rpoA 0.0029
5772 DNA-directed RNA polymerase alpha chain rpoA 0.0029
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0029
233 Potassium channel subfamily K member 2 KCNK2 0.0029
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0029
1291 cAMP response element-binding protein CREB1 0.0028
1435 Synaptic vesicle glycoprotein 2A SV2A 0.0028
78 Acetyl-CoA acetyltransferase, mitochondrial ACAT1 0.0028
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0028
1200 AMBP protein AMBP 0.0028
3866 Serum amyloid A protein SAA1 0.0028
1932 Apolipoprotein E APOE 0.0028
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0028
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0027
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0027
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0027
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0027
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0027
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0027
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0027
6232 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short GNAS 0.0027
6233 Adenylate cyclase type 2 ADCY2 0.0027
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0027
6234 Adenylate cyclase type 5 ADCY5 0.0027
199 Monocarboxylate transporter 8 SLC16A2 0.0027
1144 Hepatocyte growth factor receptor MET 0.0027
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0027
4210 Toll-like receptor 4 TLR4 0.0027
2391 Ferrochelatase hemH 0.0027
6502 Ferrochelatase DKFZp686P18130 0.0027
1591 Ferrochelatase, mitochondrial FECH 0.0027
4173 Tyrosine-protein kinase JAK2 JAK2 0.0027
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.0027
2159 Quinone oxidoreductase CRYZ 0.0027
144 Hemoglobin subunit alpha HBA1 0.0027
3849 Insulin-like growth factor-binding protein 7 IGFBP7 0.0027
2009 Protein NOV homolog NOV 0.0027
3847 Neuroendocrine convertase 2 PCSK2 0.0027
1949 Carboxypeptidase E CPE 0.0027
3850 Synaptotagmin-like protein 4 SYTL4 0.0027
3848 Neuroendocrine convertase 1 PCSK1 0.0027
3846 Retinoblastoma-associated protein RB1 0.0027
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0027
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0026
5997 Tumor necrosis factor ligand superfamily member 11 TNFSF11 0.0026
6131 Carbonic anhydrase 14 CA14 0.0026
6859 Protein S100-A4 S100A4 0.0025
2021 Thrombomodulin THBD 0.0025
3959 Cell division protein kinase 4 CDK4 0.0025
1385 Angiotensin-converting enzyme 2 ACE2 0.0025
3913 Glutamic acid decarboxylase GAD65 0.0025
6033 High affinity interleukin-8 receptor A CXCR1 0.0025
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0025
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0025
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0025
390 Adenosine A3 receptor ADORA3 0.0025
3482 Cell division protein kinase 7 CDK7 0.0025
400 Coagulation factor IX F9 0.0024
5461 Coagulation factor IX F9 0.0024
4041 Microsomal glutathione S-transferase 2 MGST2 0.0024
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0024
544 Potassium voltage-gated channel subfamily E member 1 KCNE1 0.0024
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0024
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.0024
6039 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A PDE11A 0.0024
6122 Carbonic anhydrase 3 CA3 0.0024
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0024
6070 Nischarin NISCH 0.0024
5852 Type-2 angiotensin II receptor AGTR2 0.0024
6171 Solute carrier family 28 member 3 SLC28A3 0.0024
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.0024
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.0024
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.0024
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.0024
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.0024
6493 Cytochrome c oxidase subunit 6C COX6C 0.0024
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.0024
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.0024
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.0024
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0024
6559 Cytochrome c oxidase subunit 2 ctaC 0.0024
6669 Cytochrome c oxidase subunit 2 ctaC 0.0024
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.0024
371 Cytochrome c oxidase subunit 1 MT-CO1 0.0024
6558 Cytochrome c oxidase subunit 1 ctaD 0.0024
1770 Phospholipase C PLCL1 0.0024
2841 Phospholipase C plc 0.0024
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0024
642 3-oxo-5-alpha-steroid 4-dehydrogenase 2 SRD5A2 0.0023
3955 Cell division protein kinase 6 CDK6 0.0023
4221 Vascular endothelial growth factor VEGF 0.0023
5816 Cadherin-5 CDH5 0.0023
550 Amiloride-sensitive sodium channel subunit delta SCNN1D 0.0023
27 Amiloride-sensitive sodium channel subunit beta SCNN1B 0.0023
552 Amiloride-sensitive sodium channel subunit gamma SCNN1G 0.0023
213 Amiloride-sensitive sodium channel subunit alpha SCNN1A 0.0023
1830 5'-nucleotidase NT5E 0.0023
2240 Cell division protein kinase 2 CDK2 0.0023
1341 Histamine H3 receptor HRH3 0.0023
822 Aldose reductase AKR1B1 0.0023
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0022
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0022
604 Vitamin K-dependent protein Z PROZ 0.0022
707 72 kDa type IV collagenase MMP2 0.0022
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0022
6111 DNA polymerase epsilon subunit 4 POLE4 0.0022
6112 DNA polymerase epsilon subunit 3 POLE3 0.0022
6110 DNA polymerase epsilon subunit 2 POLE2 0.0022
6108 Ribonucleoside-diphosphate reductase subunit M2 B RRM2B 0.0022
6109 DNA polymerase epsilon catalytic subunit A POLE 0.0022
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.0022
3404 Exotoxin A eta 0.0022
2540 Choloylglycine hydrolase cbh 0.0022
2155 Insulin-degrading enzyme IDE 0.0022
2232 Interleukin-5 IL5 0.0022
298 Renin REN 0.0021
1593 Mucin-2 MUC2 0.0021
2091 Endoplasmin HSP90B1 0.0021
6211 Tubulin epsilon chain TUBE1 0.0021
6212 Tubulin gamma-1 chain TUBG1 0.0021
6210 Tubulin delta chain TUBD1 0.0021
735 Alanine aminotransferase 1 GPT 0.0021
1244 Low-density lipoprotein receptor-related protein 2 LRP2 0.0021
3904 Alanine aminotransferase 2 GPT2 0.0021
63 Malate dehydrogenase mdh 0.0021
2329 Malate dehydrogenase mdh 0.0021
3445 Malate dehydrogenase mdh 0.0021
4420 Malate dehydrogenase mdh 0.0021
4438 Malate dehydrogenase mdh 0.0021
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0021
2207 Rhodopsin RHO 0.0021
828 Phenylalanine-4-hydroxylase PAH 0.0021
3109 Phenylalanine-4-hydroxylase phhA 0.0021
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.002
422 Vitamin K-dependent protein C PROC 0.002
1245 Vitamin K-dependent protein S PROS1 0.002
6501 Fatty acid-binding protein, liver FABP1 0.002
3090 Chitosanase csn 0.002
4149 Nuclear factor NF-kappa-B p100 subunit NFKB2 0.002
6459 Glycodelin PAEP 0.002
1742 D-HSCDK2 CDK2deltaT 0.002
1771 Cell division control protein 2 homolog CDK1 0.002
3321 Cell division control protein 2 homolog CRK2 0.002
5433 UPF0230 protein TM_1468 TM_1468 0.002
3616 Fatty acid-binding protein, epidermal FABP5 0.002
5431 Lipid binding protein Not Available 0.002
5430 Hepatocyte nuclear factor 4-gamma HNF4G 0.002
4218 Ribonucleoside-diphosphate reductase M2 subunit RRM2 0.002
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.002
1058 Cell division protein kinase 5 CDK5 0.002
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0019
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0019
4031 Glutathione S-transferase A1 GSTA1 0.0019
473 L-lactate dehydrogenase A chain LDHA 0.0019
893 [Citrate [pro-3S]-lyase] ligase citC 0.0018
845 Pyruvate dehydrogenase [cytochrome] poxB 0.0018
1253 Interferon gamma IFNG 0.0018
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0018
1968 ATP-sensitive inward rectifier potassium channel 12 KCNJ12 0.0018
327 Glutathione reductase gor 0.0018
5110 Glutathione reductase GR2 0.0018
1123 Eosinophil cationic protein RNASE3 0.0018
2408 Tyrosine-protein kinase SYK SYK 0.0018
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0017
1792 Tissue-type plasminogen activator PLAT 0.0017
3221 Cytochrome c4 cc4 0.0017
2290 ADP-ribosyl cyclase 2 BST1 0.0017
6500 Phospholipase A2 PLA2G1B 0.0017
283 SEC14-like protein 2 SEC14L2 0.0017
1928 Leukotriene C4 synthase LTC4S 0.0017
4034 Glutaredoxin-1 GLRX 0.0017
907 Glutathione peroxidase 2 GPX2 0.0017
4037 Hypothetical protein GPX1 0.0017
4297 Hypothetical protein SP_1951 0.0017
4521 Hypothetical protein BC_2969 0.0017
4540 Hypothetical protein TM_1070 0.0017
4555 Hypothetical protein MT1739 0.0017
4569 Hypothetical protein mshD 0.0017
4578 Hypothetical protein PA3270 0.0017
4747 Hypothetical protein PA3967 0.0017
5177 Hypothetical protein TM_0096 0.0017
5194 Hypothetical protein PA1204 0.0017
5240 Hypothetical protein Rv2991 0.0017
5370 Hypothetical protein TM_1158 0.0017
5710 Hypothetical protein Tb927.5.1360 0.0017
4029 Microsomal glutathione S-transferase 3 MGST3 0.0017
4032 Microsomal glutathione S-transferase 1 MGST1 0.0017
4043 Glutaredoxin-2, mitochondrial GLRX2 0.0017
4030 Thioredoxin domain-containing protein 12 TXNDC12 0.0017
4033 S-formylglutathione hydrolase ESD 0.0017
4040 Glutathione peroxidase 7 GPX7 0.0017
4038 Glutathione peroxidase 4 GPX4 0.0017
1975 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial GPX4 0.0017
906 Glutathione peroxidase 1 GPX1 0.0017
4039 CDNA FLJ23636 fis, clone CAS07176 GPX8 0.0017
4035 Glutathione S-transferase Mu 5 GSTM5 0.0017
910 Epididymal secretory glutathione peroxidase GPX5 0.0017
4036 Glutathione peroxidase 6 GPX6 0.0017
900 Glutathione S-transferase A4 GSTA4 0.0017
903 Glutathione S-transferase A5 GSTA5 0.0017
911 Glutathione peroxidase 3 GPX3 0.0017
4042 Glutathione transferase omega-2 GSTO2 0.0017
1056 Gamma-glutamyltranspeptidase 1 GGT1 0.0017
6151 Monocarboxylate transporter 10 SLC16A10 0.0017
4948 Cytochrome c-553 Not Available 0.0017
4923 Cytochrome c3 DvMF_2499 0.0017
4945 Cytochrome c3 Not Available 0.0017
4949 Cytochrome c3 DVU_3171 0.0017
4968 Cytochrome c3 cytc3 0.0017
4997 Cytochrome c3 SO_2727 0.0017
5219 Cytochrome c3 cyd 0.0017
4902 Nine-heme cytochrome c Ddes_2038 0.0017
3189 High-molecular-weight cytochrome c hmcA 0.0017
798 Osteocalcin BGLAP 0.0016
1243 Cathepsin D CTSD 0.0016
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0016
2211 Fatty acid-binding protein, heart FABP3 0.0016
3007 Carbonic anhydrase 12 CA12 0.0016
4205 Carbonic anhydrase 9 CA9 0.0016
3233 Bile acid receptor NR1H4 0.0015
2853 14 kDa fatty acid-binding protein Not Available 0.0015
3319 Hydroxyacylglutathione hydrolase HAGH 0.0015
6755 Poliovirus receptor PVR 0.0015
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0015
898 Glutathione S-transferase A3 GSTA3 0.0015
897 Glutathione S-transferase kappa 1 GSTK1 0.0015
6677 Myelin P2 protein PMP2 0.0015
982 Cocaine- and amphetamine-regulated transcript protein CARTPT 0.0015
909 Maleylacetoacetate isomerase GSTZ1 0.0015
369 Coagulation factor VII F7 0.0015
3844 HLA class II histocompatibility antigen, DQ(6) alpha chain HLA-DQA2 0.0015
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.0015
905 Glutathione transferase omega-1 GSTO1 0.0015
899 Glutathione S-transferase Mu 3 GSTM3 0.0015
1525 Heparin-binding growth factor 2 FGF2 0.0015
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0015
4954 Soluble cytochrome b558 Not Available 0.0014
4934 Cytochrome c-551 nirM 0.0014
5218 Cytochrome c-551 nirM 0.0014
4905 Cytochrome c2 Not Available 0.0014
4939 Cytochrome c2 cycA 0.0014
4964 Cytochrome c2 cycA 0.0014
4979 Cytochrome c2 cycA 0.0014
6673 Cytochrome c2 cycA 0.0014
4915 Cytochrome c-550 psbV 0.0014
4959 Cytochrome c-550 psbV 0.0014
5216 Cytochrome c-550 psbV 0.0014
4925 Cytochrome c-type protein SHP shp 0.0014
4947 Bacterial hemoglobin vhb 0.0014
4998 Hemoglobin-like protein yjbI yjbI 0.0014
4975 Cytochrome c-556 RPA3973 0.0014
4943 Cytochrome c6 petJ 0.0014
4916 Cyanoglobin glbN 0.0014
4984 Neuroglobin NGB 0.0014
4936 Cytochrome c2 iso-2 Not Available 0.0014
4994 Hemoglobin-like protein HbO glbO 0.0014
4907 Cytochrome c-L moxG 0.0014
6865 Cytochrome c-L moxG 0.0014
4909 CooA protein cooA 0.0014
644 Heme oxygenase 2 HMOX2 0.0014
4982 Heme oxygenase 2 pbsA2 0.0014
4942 Diheme cytochrome c napB napB 0.0014
4935 Cytochrome c-554 cycA1 0.0014
4904 Cytochrome c family protein GSU1996 0.0014
4910 Cytoglobin CYGB 0.0014
4961 Hemophore HasA hasA 0.0014
4971 Nonaheme cytochrome c hmcA 0.0014
4981 Iron-starvation protein PigA pigA 0.0014
5000 HemO hemO 0.0014
4989 Cytochrome c551 peroxidase ccp 0.0014
5222 Cytochrome c551 peroxidase ccpA 0.0014
4976 Apocytochrome f petA 0.0014
6407 Apocytochrome f petA 0.0014
4999 Cytochrome P450 165B3 CYP165B3 0.0014
4764 Cytochrome P450 165C4 CYP165C4 0.0014
4960 Putative cytochrome P450-family protein SCO7417 0.0014
4931 Cytochrome P450 167A1 CYP167A1 0.0014
4926 Heme-based aerotactic transducer hemAT hemAT 0.0014
4937 Cytochrome oxidase subunit II rcoxA 0.0014
4993 Hydroxylamine oxidoreductase hao1 0.0014
4903 Methyl-accepting chemotaxis protein Tar4 0.0014
4922 Cytochrome c, putative SO_4144 0.0014
4972 P450cin cinA 0.0014
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0014
3093 Catalase HPII katE 0.0014
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0014
4952 Catalase/peroxidase katA 0.0014
4386 Hemoglobin-like protein HbN glbN 0.0014
2129 Sucrase-isomaltase, intestinal SI 0.0014
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0014
277 Purine nucleoside phosphorylase PNP 0.0014
2870 Purine nucleoside phosphorylase punA 0.0014
2945 Purine nucleoside phosphorylase punA 0.0014
4659 Purine nucleoside phosphorylase TM_1596 0.0014
4825 Purine nucleoside phosphorylase TTHA1435 0.0014
2165 Glutathione S-transferase Mu 2 GSTM2 0.0013
1152 Glycogen phosphorylase, muscle form PYGM 0.0013
207 Glutathione synthetase GSS 0.0013
5269 Glutathione synthetase gshB 0.0013
561 Retinol-binding protein II, cellular RBP2 0.0013
35 Dehydrogenase/reductase SDR family member 4 DHRS4 0.0013
4073 Retinol dehydrogenase 11 RDH11 0.0013
4074 Retinol dehydrogenase 14 RDH14 0.0013
1097 Lecithin retinol acyltransferase LRAT 0.0013
589 Retinoid-binding protein 7 RBP7 0.0013
753 Retinol-binding protein III, cellular RBP5 0.0013
4071 Short-chain dehydrogenase/reductase 3 DHRS3 0.0013
4075 Photoreceptor outer segment all-trans retinol dehydrogenase RDH8 0.0013
863 Cellular retinaldehyde-binding protein RLBP1 0.0013
800 Retinol dehydrogenase 12 RDH12 0.0013
282 Interphotoreceptor retinoid-binding protein RBP3 0.0013
651 Retinol dehydrogenase 13 RDH13 0.0013
4072 All-trans-retinol 13,14-reductase RETSAT 0.0013
860 Nicotinamide N-methyltransferase NNMT 0.0013
699 Nicotinic acid receptor 1 GPR109A 0.0013
928 Nicotinic acid receptor 2 GPR109B 0.0013
583 Nicotinate-nucleotide pyrophosphorylase [carboxylating] QPRT 0.0013
2442 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0013
2459 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0013
901 Glutathione S-transferase Mu 4 GSTM4 0.0012
6116 Gastric triacylglycerol lipase LIPF 0.0012
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0012
3382 Glycolipid transfer protein GLTP 0.0012
694 Matrix protein 2 M 0.0012
3823 Cytokine receptor common gamma chain IL2RG 0.0012
2297 Genome polyprotein Not Available 0.0012
2322 Genome polyprotein Not Available 0.0012
2694 Genome polyprotein Not Available 0.0012
2719 Genome polyprotein Not Available 0.0012
2860 Genome polyprotein Not Available 0.0012
2928 Genome polyprotein Not Available 0.0012
3160 Genome polyprotein Not Available 0.0012
3260 Genome polyprotein Not Available 0.0012
4783 Genome polyprotein Not Available 0.0012
5726 Genome polyprotein Not Available 0.0012
5779 Genome polyprotein Not Available 0.0012
5867 Genome polyprotein Not Available 0.0012
6253 Genome polyprotein Not Available 0.0012
6301 Genome polyprotein Not Available 0.0012
6380 Genome polyprotein Not Available 0.0012
6381 Genome polyprotein Not Available 0.0012
6437 Genome polyprotein Not Available 0.0012
6520 Genome polyprotein Not Available 0.0012
6521 Genome polyprotein Not Available 0.0012
6652 Genome polyprotein Not Available 0.0012
6734 Genome polyprotein Not Available 0.0012
6735 Genome polyprotein Not Available 0.0012
6736 Genome polyprotein Not Available 0.0012
6737 Genome polyprotein Not Available 0.0012
6738 Genome polyprotein Not Available 0.0012
6739 Genome polyprotein Not Available 0.0012
6744 Genome polyprotein Not Available 0.0012
6748 Genome polyprotein Not Available 0.0012
6894 Genome polyprotein Not Available 0.0012
6898 Genome polyprotein Not Available 0.0012
338 DNA polymerase UL30 0.0012
379 DNA polymerase UL54 0.0012
697 DNA polymerase ORF28 0.0012
2482 DNA polymerase 43 0.0012
4104 DNA polymerase BALF5 0.0012
997 Protein kinase C beta type PRKCB 0.0012
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0012
1295 Fatty acid synthase FASN 0.0012
1268 Neuropeptide S receptor NPSR1 0.0012
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0012
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0012
331 Retinol-binding protein I, cellular RBP1 0.0012
627 11-cis retinol dehydrogenase RDH5 0.0011
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0011
1970 Protein kinase C alpha type PRKCA 0.0011
754 Pancreatic triacylglycerol lipase PNLIP 0.0011
1507 Cytochrome c CYCS 0.0011
6073 Potassium channel subfamily K member 9 KCNK9 0.0011
6072 Potassium channel subfamily K member 3 KCNK3 0.0011
4920 Peroxidase/catalase katG 0.0011
2178 Metabotropic glutamate receptor 5 GRM5 0.0011
724 Interleukin-2 receptor alpha chain IL2RA 0.0011
717 Interleukin-2 receptor subunit beta IL2RB 0.0011
2119 Cytochrome b5 CYB5A 0.0011
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.001
4990 PpcA ppcA 0.001
4988 Sulfite oxidase, mitochondrial SUOX 0.001
3375 Acidic cytochrome c3 Not Available 0.001
4385 Cytochrome c' Not Available 0.001
4967 Cytochrome c' cycA 0.001
5038 Cytochrome c' Not Available 0.001
5223 Cytochrome c' cycP 0.001
2915 Sensor protein fixL fixL 0.001
4944 Sensor protein fixL fixL 0.001
3570 Cytochrome P450 152A1 cypC 0.001
4992 Cytochrome c peroxidase Not Available 0.001
4813 Heme oxygenase hmuO 0.001
5769 Heme oxygenase Not Available 0.001
4289 Cytochrome P450 TT_P0059 0.001
6262 Cytochrome P450 staP 0.001
1810 Protein S100-A1 S100A1 0.001
6097 Protein S100-A2 S100A2 0.001
2230 Catalase CAT 0.001
3249 Catalase katA 0.001
3625 Catalase katA 0.001
4539 Catalase katA 0.001
4941 Catalase katB 0.001
493 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial CYP27B1 0.001
345 Plasma retinol-binding protein RBP4 0.001
2473 Tyrosine-protein kinase CSK CSK 0.001
2398 Tyrosine-protein kinase ZAP-70 ZAP70 0.001
2268 Cholesterol oxidase choB 0.0009
2822 Cholesterol oxidase choA 0.0009
1064 DNA (cytosine-5)-methyltransferase 1 DNMT1 0.0009
6105 3-oxo-5-beta-steroid 4-dehydrogenase AKR1D1 0.0009
3670 Soluble cytochrome b562 precursor cybC 0.0009
3411 Cytochrome P450 121 cyp121 0.0009
3291 Cytochrome c-552 cycA 0.0009
4927 Cytochrome c-552 nrfA 0.0009
4938 Cytochrome c-552 cycA 0.0009
4953 Cytochrome c-552 nrfA 0.0009
5217 Cytochrome c-552 cycM 0.0009
2617 Nitric oxide synthase oxygenase nos 0.0009
2701 Nitric oxide synthase oxygenase nos 0.0009
1048 Protein S100-A13 S100A13 0.0009
2226 Protein S100-A12 S100A12 0.0009
3102 Flavohemoprotein hmp 0.0009
4969 Flavohemoprotein hmp 0.0009
2283 Steroid Delta-isomerase ksi 0.0009
2920 Steroid Delta-isomerase ksi 0.0009
2132 Protein S100-B S100B 0.0009
22 30S ribosomal protein S4 rpsD 0.0008
6714 30S ribosomal protein S4 rpsD 0.0008
2325 Sulfotransferase family cytosolic 2B member 1 SULT2B1 0.0008
2972 6-deoxyerythronolide B hydroxylase eryF 0.0008
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0008
1867 Major prion protein PRNP 0.0008
500 Monocarboxylate transporter 4 SLC16A3 0.0008
1649 Small inducible cytokine A2 CCL2 0.0008
2530 Protein kinase C theta type PRKCQ 0.0008
4608 Putative cytochrome P450 SCO1207 0.0008
4963 Putative cytochrome P450 SCO2884 0.0008
6254 Putative cytochrome P450 SCO6998 0.0008
1025 Aquaporin-1 AQP1 0.0008
866 Large neutral amino acids transporter small subunit 2 SLC7A8 0.0007
358 Cystathionine beta-synthase CBS 0.0007
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0007
6207 30S ribosomal protein S14 rpsN 0.0007
6209 30S ribosomal protein S19 rpsS 0.0007
6712 30S ribosomal protein S19 rpsS 0.0007
6726 30S ribosomal protein S19 rpsS 0.0007
6134 Sodium channel subunit beta-3 SCN3B 0.0007
6133 Sodium channel subunit beta-2 SCN2B 0.0007
6135 Sodium channel subunit beta-4 SCN4B 0.0007
6132 Sodium channel subunit beta-1 SCN1B 0.0007
6129 Carbonic anhydrase-related protein 11 CA11 0.0007
6127 Carbonic anhydrase-related protein CA8 0.0007
6128 Carbonic anhydrase-related protein 10 CA10 0.0007
645 Penicillin-binding protein 1A mrcA 0.0007
5805 Penicillin-binding protein 1A ponA 0.0007
6185 Penicillin-binding protein 1A mrcA 0.0007
6799 Penicillin-binding protein 1A pbpA 0.0007
693 Hemoglobin subunit beta HBB 0.0007
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0007
226 Gonadotropin-releasing hormone receptor GNRHR 0.0007
125 DNA polymerase beta POLB 0.0007
6268 Hydroxyacid oxidase 1 HAO1 0.0006
810 Heme oxygenase 1 HMOX1 0.0006
3391 Heme oxygenase 1 pbsA1 0.0006
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0006
6130 Carbonic anhydrase 13 CA13 0.0006
5221 Cytochrome c3, 13 kDa Not Available 0.0006
3152 Cytochrome c'' cycA 0.0006
5220 Split-Soret cytochrome c Ddes_2150 0.0006
3700 Cytochrome c-552 precursor nrfA 0.0006
1721 Glycogen synthase kinase-3 beta GSK3B 0.0005
3238 Multidrug resistance protein mexA mexA 0.0005
3116 Bacterioferritin bfr 0.0005
4906 Bacterioferritin bfr 0.0005
4965 Bacterioferritin bfr 0.0005
3173 Enolase eno 0.0005
3709 Glycerol uptake facilitator protein glpF 0.0005
3336 C4-dicarboxylate transport transcriptional regulatory protein dctD dctD 0.0005
3393 TGF-beta receptor type-2 TGFBR2 0.0005
5489 Ribonucleoside-diphosphate reductase 1 subunit beta nrdB 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
2852 DNA mismatch repair protein mutL mutL 0.0005
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0005
3191 Histidinol dehydrogenase hisD 0.0005
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0004
4692 A/G-specific adenine glycosylase mutY 0.0004
2802 Endoglucanase G celCCG 0.0004
340 Apoptotic protease-activating factor 1 APAF1 0.0004
6316 ADP-ribosylation factor 1 ARF1 0.0004
825 Arsenical pump-driving ATPase ASNA1 0.0003
3435 Arsenical pump-driving ATPase arsA 0.0003
486 Serine/threonine-protein kinase ALS2CR7 CDK15 0.0003
2105 ATP-binding cassette sub-family G member 1 ABCG1 0.0003
377 Beta-adrenergic receptor kinase 1 ADRBK1 0.0003
510 Serine/threonine-protein kinase receptor R3 ACVRL1 0.0003
733 Activin receptor type 1B ACVR1B 0.0003
225 NEDD8-activating enzyme E1 regulatory subunit NAE1 0.0003
745 Anti-Muellerian hormone type-2 receptor AMHR2 0.0003
483 A-Raf proto-oncogene serine/threonine-protein kinase ARAF 0.0003
21 Beta-adrenergic receptor kinase 2 ADRBK2 0.0003
154 AFG3-like protein 2 AFG3L2 0.0003
395 ALK tyrosine kinase receptor Not Available 0.0003
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0003
292 Activin receptor type-1 ACVR1 0.0003
849 Activated CDC42 kinase 1 TNK2 0.0003
704 Long-chain-fatty-acid--CoA ligase 1 ACSL1 0.0003
821 Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 0.0003
386 Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 0.0003
297 Adenylate cyclase type 1 ADCY1 0.0003
289 Cytosolic purine 5'-nucleotidase NT5C2 0.0003
740 Argininosuccinate synthase ASS1 0.0002
865 Argininosuccinate synthase ASS1 0.0002
2680 Argininosuccinate synthase argG 0.0002
3194 Argininosuccinate synthase argG 0.0002
661 ADP/ATP translocase 1 SLC25A4 0.0002
6021 Adenosine kinase ADK 0.0002
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0002
↑