| Name |
Tumor necrosis factor ligand superfamily member 11 |
| Synonyms |
7745 |
| Gene name |
TNFSF11 |
| General function |
Not Available |
| Specific function |
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy |
| Gene sequence |
+ ...
Not Available
|
| Protein sequence |
+ ...
MRRASRDYTKYLRGSEEMGGGPGAPHEGPLHAPPPPAPHQPPAASRSMFVALLGLGLGQVVCSVALFFYFRAQMDPNRISEDGTHCIYRILRLHENADFQDTTLESQDTKLIPDSCRRIKQAFQGAVQKELQHIVGSQHIRAEKAMVDGSWLDLAKRSKLEAQPFAHLTINATDIPSGSHKVSLSSWYHDRGWAKISNMTFSNGKLIVNQDGFYYLYANICFRHHETSGDLATEYLQLMVYVTKTSIKIPSSHTLMKGGSTKYWSGNSEFHFYSINVGGFFKLRSGEEISIEVSNPSLLDPDQDATYFGAFKVRDID
|
| GO Classification |
| component |
| cell |
| membrane |
| function |
| tumor necrosis factor receptor binding |
| signal transducer activity |
| receptor binding |
| cytokine activity |
| process |
| response to stimulus |
| response to biotic stimulus |
| defense response |
| immune response |
|
|
See more information at →
www.drugbank.ca
|