Name |
Tumor necrosis factor ligand superfamily member 11 |
Synonyms |
7745 |
Gene name |
TNFSF11 |
General function |
Not Available |
Specific function |
Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy |
Gene sequence |
+ ...
Not Available
|
Protein sequence |
+ ...
MRRASRDYTKYLRGSEEMGGGPGAPHEGPLHAPPPPAPHQPPAASRSMFVALLGLGLGQVVCSVALFFYFRAQMDPNRISEDGTHCIYRILRLHENADFQDTTLESQDTKLIPDSCRRIKQAFQGAVQKELQHIVGSQHIRAEKAMVDGSWLDLAKRSKLEAQPFAHLTINATDIPSGSHKVSLSSWYHDRGWAKISNMTFSNGKLIVNQDGFYYLYANICFRHHETSGDLATEYLQLMVYVTKTSIKIPSSHTLMKGGSTKYWSGNSEFHFYSINVGGFFKLRSGEEISIEVSNPSLLDPDQDATYFGAFKVRDID
|
GO Classification |
component |
cell |
membrane |
function |
tumor necrosis factor receptor binding |
signal transducer activity |
receptor binding |
cytokine activity |
process |
response to stimulus |
response to biotic stimulus |
defense response |
immune response |
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