DT-Web

DB02266 - Flufenamic Acid


Identification
Name Flufenamic Acid
Accession Number DB02266 (EXPT01442)
Type small molecule
Description An anthranilic acid derivative with analgesic, anti-inflammatory, and antipyretic properties. It is used in musculoskeletal and joint disorders and administered by mouth and topically. (From Martindale, The Extra Pharmacopoeia, 30th ed, p16)
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 281.2299
Groups experimental
Monoisotopic Weight 281.066363184
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Prostaglandin G/H synthase 2
Name Prostaglandin G/H synthase 2
Gene Name PTGS2
Pharmacological action unknown
Actions Not Available
References
  • Ouellet M, Percival MD: Effect of inhibitor time-dependency on selectivity towards cyclooxygenase isoforms. Biochem J. 1995 Feb 15;306 ( Pt 1):247-51. - Pubmed
DTHybrid score 0.5587
Prostaglandin G/H synthase 1
Name Prostaglandin G/H synthase 1
Gene Name PTGS1
Pharmacological action unknown
Actions Not Available
References
  • Ouellet M, Percival MD: Effect of inhibitor time-dependency on selectivity towards cyclooxygenase isoforms. Biochem J. 1995 Feb 15;306 ( Pt 1):247-51. - Pubmed
DTHybrid score 0.5999
Aldo-keto reductase family 1 member C3
Name Aldo-keto reductase family 1 member C3
Gene Name AKR1C3
Pharmacological action unknown
Actions Not Available
References
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Lovering AL, Ride JP, Bunce CM, Desmond JC, Cummings SM, White SA: Crystal structures of prostaglandin D(2) 11-ketoreductase (AKR1C3) in complex with the nonsteroidal anti-inflammatory drugs flufenamic acid and indomethacin. Cancer Res. 2004 Mar 1;64(5):1802-10. - Pubmed
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.5449
Androgen receptor
Name Androgen receptor
Gene Name AR
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.0652

Transporters


Solute carrier family 22 member 6
Name Solute carrier family 22 member 6
Gene Name SLC22A6
Actions inhibitor
References
  • Uwai Y, Saito H, Inui K: Interaction between methotrexate and nonsteroidal anti-inflammatory drugs in organic anion transporter. Eur J Pharmacol. 2000 Dec 1;409(1):31-6. - Pubmed
DTHybrid score 0.312

Carriers


Solute carrier family 22 member 6
Name Solute carrier family 22 member 6
Gene Name SLC22A6
Actions
References Not Available
DTHybrid score 0.312

Predictions


Id Partner name Gene Name Score
4757 Cytochrome P450 2C9 CYP2C9 0.1431
4512 Cytochrome P450 3A4 CYP3A4 0.1058
587 Serum albumin ALB 0.0914
4924 Cytochrome P450 2C8 CYP2C8 0.0869
6142 Solute carrier family 22 member 8 SLC22A8 0.0865
3811 Cytochrome P450 19A1 CYP19A1 0.0696
6016 Cytochrome P450 2C19 CYP2C19 0.0675
1024 Solute carrier family 22 member 11 SLC22A11 0.0611
4200 Cytochrome P450 1A2 CYP1A2 0.0606
672 Prostaglandin F2-alpha receptor PTGFR 0.0526
1588 Multidrug resistance protein 1 ABCB1 0.0518
4119 Cytochrome P450 2D6 CYP2D6 0.0503
275 Arachidonate 5-lipoxygenase ALOX5 0.0498
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0484
2972 6-deoxyerythronolide B hydroxylase eryF 0.0468
6143 Solute carrier family 22 member 7 SLC22A7 0.0407
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.04
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0395
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0395
756 Sex hormone-binding globulin SHBG 0.0394
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0357
2164 Multidrug resistance-associated protein 4 ABCC4 0.035
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0342
614 Progesterone receptor PGR 0.0336
1757 Myeloperoxidase MPO 0.0327
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0319
737 Mineralocorticoid receptor NR3C2 0.0311
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0306
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0289
1275 Estrogen sulfotransferase SULT1E1 0.028
6013 Cytochrome P450 2E1 CYP2E1 0.0276
6024 Cytochrome P450 1A1 CYP1A1 0.0273
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0261
6012 Tryptophan 2,3-dioxygenase TDO2 0.0251
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0243
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0238
4118 Cytochrome P450 3A5 CYP3A5 0.0229
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0229
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0227
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0222
6030 Cytochrome P450 2B6 CYP2B6 0.0221
862 Multidrug resistance-associated protein 1 ABCC1 0.0213
3923 Cholinesterase BCHE 0.0204
3312 Fatty acid-binding protein, brain FABP7 0.0199
136 Estrogen receptor ESR1 0.0197
871 Glucocorticoid receptor NR3C1 0.0192
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0191
6258 Protein S100-A7 S100A7 0.0191
1159 Interleukin-6 IL6 0.0185
578 Endothelin-1 receptor EDNRA 0.0182
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0181
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0179
738 Monocarboxylate transporter 1 SLC16A1 0.0177
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0177
118 Organic cation/carnitine transporter 2 SLC22A5 0.0176
5718 Cytochrome P450 2A6 CYP2A6 0.0171
723 Cytosolic phospholipase A2 PLA2G4A 0.0167
6241 Nuclear receptor coactivator 2 NCOA2 0.0166
6106 Cytochrome P450 2C18 CYP2C18 0.0156
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0154
3810 Catechol O-methyltransferase COMT 0.0152
633 Penicillin-binding proteins 1A/1B pbpA 0.0149
1898 Cytochrome P450 1B1 CYP1B1 0.0147
6220 Aryl hydrocarbon receptor AHR 0.0147
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0143
4120 NADPH--cytochrome P450 reductase POR 0.0143
592 Carbonic anhydrase 4 CA4 0.0141
2183 Fatty acid-binding protein, adipocyte FABP4 0.014
404 DNA gyrase subunit A gyrA 0.0139
6224 DNA gyrase subunit A gyrA 0.0139
295 Carbonic anhydrase 1 CA1 0.0133
520 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.0132
2306 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.0132
2367 UDP-N-acetylglucosamine 1-carboxyvinyltransferase murA 0.0132
703 NADPH azoreductase azr 0.0132
381 Prolactin receptor PRLR 0.013
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0129
6141 Sodium/bile acid cotransporter SLC10A1 0.0128
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0126
1507 Cytochrome c CYCS 0.0126
817 DNA topoisomerase 2-alpha TOP2A 0.0125
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0124
850 Vasopressin V1b receptor AVPR1B 0.0122
308 30S ribosomal protein S12 rpsL 0.0122
6704 30S ribosomal protein S12 rpsL 0.0122
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0122
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0122
3947 Xanthine dehydrogenase/oxidase XDH 0.0121
6107 Cytochrome P450 3A7 CYP3A7 0.0121
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.012
777 Tumor necrosis factor TNF 0.0117
338 DNA polymerase UL30 0.0116
379 DNA polymerase UL54 0.0116
697 DNA polymerase ORF28 0.0116
2482 DNA polymerase 43 0.0116
4104 DNA polymerase BALF5 0.0116
357 Carbonic anhydrase 2 CA2 0.0116
853 Farnesyl pyrophosphate synthetase FDPS 0.0113
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0112
558 Solute carrier family 12 member 1 SLC12A1 0.0112
4790 Glycosyltransferase GtfA gtfA 0.011
185 Vasopressin V1a receptor AVPR1A 0.0107
776 Bile salt export pump ABCB11 0.0107
322 Vasopressin V2 receptor AVPR2 0.0105
3941 Amine oxidase [flavin-containing] A MAOA 0.0105
6145 Solute carrier family 22 member 1 SLC22A1 0.0105
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0105
6043 Putative G-protein coupled receptor 44 GPR44 0.0103
3639 Thymidine phosphorylase deoA 0.0103
3936 Thymidine phosphorylase TYMP 0.0103
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0101
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.01
645 Penicillin-binding protein 1A mrcA 0.01
5805 Penicillin-binding protein 1A ponA 0.01
6185 Penicillin-binding protein 1A mrcA 0.01
6799 Penicillin-binding protein 1A pbpA 0.01
6137 Multidrug resistance-associated protein 6 ABCC6 0.01
1439 Lactotransferrin LTF 0.0098
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0098
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0098
6148 Multidrug resistance-associated protein 7 ABCC10 0.0095
2236 Casein kinase II subunit alpha CSNK2A1 0.0094
6144 Solute carrier family 22 member 2 SLC22A2 0.0093
5849 cAMP-dependent protein kinase type I-alpha regulatory subunit PRKAR1A 0.0092
130 Prostacyclin synthase PTGIS 0.0091
1244 Low-density lipoprotein receptor-related protein 2 LRP2 0.009
4132 Chloride channel protein ClC-Ka CLCNKA 0.009
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0088
380 Cytochrome P450 17A1 CYP17A1 0.0088
782 ADP/ATP translocase 2 SLC25A5 0.0086
688 ADP/ATP translocase 3 SLC25A6 0.0086
1558 Transient receptor potential cation channel subfamily V member 1 TRPV1 0.0086
6102 Arylamine N-acetyltransferase 2 NAT2 0.0085
596 3-oxo-5-alpha-steroid 4-dehydrogenase 1 SRD5A1 0.0082
594 Thyroxine-binding globulin SERPINA7 0.0082
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0082
2016 Dipeptidase 1 DPEP1 0.0082
7 Nitric oxide synthase, inducible NOS2 0.0082
6126 Carbonic anhydrase 7 CA7 0.0082
1648 Elastin ELN 0.0082
291 Nitric-oxide synthase, endothelial NOS3 0.0081
5997 Tumor necrosis factor ligand superfamily member 11 TNFSF11 0.0081
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0081
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0081
758 Thyroid hormone receptor alpha THRA 0.008
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.008
61 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0079
2644 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0079
2710 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase folK 0.0079
822 Aldose reductase AKR1B1 0.0079
346 Thyroid hormone receptor beta-1 THRB 0.0079
3939 Amine oxidase [flavin-containing] B MAOB 0.0078
6033 High affinity interleukin-8 receptor A CXCR1 0.0077
543 Penicillin-binding protein 1B mrcB 0.0077
6186 Penicillin-binding protein 1B ponB 0.0077
6822 Penicillin-binding protein 1b pbp1b 0.0077
6844 Penicillin-binding protein 1b pbp1b 0.0077
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0076
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0076
4221 Vascular endothelial growth factor VEGF 0.0075
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0075
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0075
5816 Cadherin-5 CDH5 0.0075
76 Nitric-oxide synthase, brain NOS1 0.0074
6149 Solute carrier family 22 member 10 SLC22A10 0.0073
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0072
22 30S ribosomal protein S4 rpsD 0.0072
6714 30S ribosomal protein S4 rpsD 0.0072
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.0071
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.007
1714 Mitogen-activated protein kinase 3 MAPK3 0.007
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0069
140 30S ribosomal protein S9 rpsI 0.0068
6719 30S ribosomal protein S9 rpsI 0.0068
6725 30S ribosomal protein S9 rpsI 0.0068
1650 Heme carrier protein 1 SLC46A1 0.0068
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0068
654 Flavin reductase BLVRB 0.0067
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0066
833 Organic cation/carnitine transporter 1 SLC22A4 0.0066
661 ADP/ATP translocase 1 SLC25A4 0.0064
477 DNA topoisomerase 4 subunit A parC 0.0064
886 DNA topoisomerase 4 subunit A parC 0.0064
6226 DNA topoisomerase 4 subunit A parC 0.0064
1649 Small inducible cytokine A2 CCL2 0.0063
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0062
6136 Multidrug resistance-associated protein 5 ABCC5 0.0061
3823 Cytokine receptor common gamma chain IL2RG 0.0061
869 Estrogen receptor beta ESR2 0.006
5626 Nucleoside diphosphate kinase B NME2 0.006
6168 Solute carrier family 22 member 16 SLC22A16 0.006
134 Tryptophan 5-hydroxylase 1 TPH1 0.006
78 Acetyl-CoA acetyltransferase, mitochondrial ACAT1 0.0059
489 Monocarboxylate transporter 2 SLC16A7 0.0059
2320 Thymidine kinase, cytosolic TK1 0.0059
70 Type-1 angiotensin II receptor AGTR1 0.0058
2981 Phospholipase A2, membrane associated PLA2G2A 0.0058
459 Retinoic acid receptor RXR-alpha RXRA 0.0057
6500 Phospholipase A2 PLA2G1B 0.0057
759 Free fatty acid receptor 1 FFAR1 0.0056
1818 Long-chain-fatty-acid--CoA ligase 3 ACSL3 0.0056
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0056
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0056
6014 Cytochrome P450 2A13 CYP2A13 0.0055
6085 Fatty acid-binding protein, intestinal FABP2 0.0055
466 Solute carrier family 12 member 3 SLC12A3 0.0055
226 Gonadotropin-releasing hormone receptor GNRHR 0.0054
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0054
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0054
6131 Carbonic anhydrase 14 CA14 0.0054
676 Tyrosine 3-monooxygenase TH 0.0054
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0053
724 Interleukin-2 receptor alpha chain IL2RA 0.0053
717 Interleukin-2 receptor subunit beta IL2RB 0.0053
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0052
492 Histamine H1 receptor HRH1 0.0051
438 Taste receptor type 1 member 2 TAS1R2 0.0051
253 Sodium/potassium-transporting ATPase gamma chain FXYD2 0.0051
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.005
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.005
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.0049
1053 BC269730_2 FADS1 0.0049
1395 Sodium/calcium exchanger 1 SLC8A1 0.0049
828 Phenylalanine-4-hydroxylase PAH 0.0049
3109 Phenylalanine-4-hydroxylase phhA 0.0049
277 Purine nucleoside phosphorylase PNP 0.0049
2870 Purine nucleoside phosphorylase punA 0.0049
2945 Purine nucleoside phosphorylase punA 0.0049
4659 Purine nucleoside phosphorylase TM_1596 0.0049
4825 Purine nucleoside phosphorylase TTHA1435 0.0049
5294 Nucleoside diphosphate kinase A NME1 0.0048
646 Malate dehydrogenase, cytoplasmic MDH1 0.0048
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0047
823 Fibroblast growth factor receptor 2 FGFR2 0.0047
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0047
666 NADP-dependent malic enzyme ME1 0.0047
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0047
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0047
33 Cystine/glutamate transporter SLC7A11 0.0047
3917 Methylenetetrahydrofolate reductase MTHFR 0.0046
3686 Acyl-CoA thioesterase I precursor tesA 0.0045
199 Monocarboxylate transporter 8 SLC16A2 0.0045
1656 CYP2B protein CYP2B 0.0045
992 Protein tyrosine kinase 2 beta PTK2B 0.0045
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0045
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0045
6339 Ig kappa chain V-II region RPMI 6410 Not Available 0.0044
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0044
3601 Dihydropteroate synthase 1 folP1 0.0044
3807 Dihydropteroate synthase 1 folP1 0.0044
3808 Dihydropteroate synthase 2 folP2 0.0044
663 Solute carrier family 12 member 4 SLC12A4 0.0044
53 Solute carrier family 12 member 5 SLC12A5 0.0044
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0043
4403 Protein iolS iolS 0.0043
5330 General stress protein 69 yhdN 0.0043
5322 Oxidoreductase ydhF ydhF 0.0043
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0043
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0043
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0043
5332 MtdA bifunctional protein mtdA 0.0043
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0043
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0043
3778 NAD(P) transhydrogenase subunit beta pntB 0.0043
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0043
5698 Riboflavin synthase alpha chain ribE 0.0043
115 Penicillin-binding protein 2 mrdA 0.0041
6069 Penicillin-binding protein 2 mrdA 0.0041
6118 Penicillin-binding protein 2 penA 0.0041
6187 Penicillin-binding protein 2 pbpA 0.0041
6686 Penicillin-binding protein 2 pbp2 0.0041
6939 Penicillin-binding protein 2 mrdA 0.0041
7163 Penicillin-binding protein 2 pbpA 0.0041
887 DNA gyrase subunit B gyrB 0.0041
4150 DNA gyrase subunit B gyrB 0.0041
6225 DNA gyrase subunit B gyrB 0.0041
408 Riboflavin kinase RFK 0.0041
310 Solute carrier family 12 member 2 SLC12A2 0.0041
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0041
24 Thymidylate synthase TMP1 0.0041
359 Thymidylate synthase TYMS 0.0041
2626 Thymidylate synthase thyA 0.0041
2729 Thymidylate synthase thyA 0.0041
5352 Thymidylate synthase THYA 0.0041
811 Translocator protein TSPO 0.004
6147 Solute carrier family 22 member 3 SLC22A3 0.004
2021 Thrombomodulin THBD 0.004
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.004
232 Corticosteroid-binding globulin SERPINA6 0.0039
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0039
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0039
1 Peptidoglycan synthetase ftsI ftsI 0.0038
4155 Peptidoglycan synthetase ftsI ftsI 0.0038
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0038
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0038
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.0038
1192 Sulfotransferase 1A1 SULT1A1 0.0038
5073 Ferredoxin--NADP reductase petH 0.0038
5076 Ferredoxin--NADP reductase fpr 0.0038
5119 Ferredoxin--NADP reductase petH 0.0038
5121 Ferredoxin--NADP reductase fpr 0.0038
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0038
5353 Glutamate decarboxylase alpha gadA 0.0037
2853 14 kDa fatty acid-binding protein Not Available 0.0037
4582 Putative pteridine reductase 2 ptr2 0.0037
1789 Lymphotoxin-alpha LTA 0.0037
1269 Tumor necrosis factor receptor superfamily member 1B TNFRSF1B 0.0037
6228 Nuclear receptor coactivator 1 NCOA1 0.0037
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0037
989 L-xylulose reductase DCXR 0.0037
5328 Prostaglandin F synthase Tb11.02.2310 0.0037
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0037
2636 Shikimate dehydrogenase aroE 0.0037
3515 Shikimate dehydrogenase aroE 0.0037
3446 NADP-dependent alcohol dehydrogenase adh 0.0037
2286 Isocitrate dehydrogenase [NADP] icd 0.0037
2302 Isocitrate dehydrogenase [NADP] icd 0.0037
2771 Isocitrate dehydrogenase [NADP] icd 0.0037
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0037
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0037
3809 Estrogen-related receptor gamma ESRRG 0.0036
244 Angiotensin-converting enzyme ACE 0.0036
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0035
444 Alcohol dehydrogenase 1B ADH1B 0.0035
889 3-oxoacyl-[acyl-carrier-protein] synthase 1 fabB 0.0035
6860 3-oxoacyl-[acyl-carrier-protein] synthase 1 kasA 0.0035
6151 Monocarboxylate transporter 10 SLC16A10 0.0035
1050 Bile salt sulfotransferase SULT2A1 0.0034
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.0034
908 Glutathione S-transferase theta-1 GSTT1 0.0034
6297 Prostaglandin reductase 1 PTGR1 0.0034
4531 Putative ketoacyl reductase actIII 0.0034
3062 Aspartate-semialdehyde dehydrogenase asd 0.0034
5325 2,4-dienoyl-CoA reductase, mitochondrial DECR1 0.0034
3932 Glutathione S-transferase A2 GSTA2 0.0034
65 Matrix metalloproteinase-9 Not Available 0.0033
6122 Carbonic anhydrase 3 CA3 0.0033
365 Dihydrofolate reductase DHFR 0.0033
2381 Dihydrofolate reductase DFR1 0.0033
2833 Dihydrofolate reductase Not Available 0.0033
2931 Dihydrofolate reductase folA 0.0033
3544 Dihydrofolate reductase folA 0.0033
3682 Dihydrofolate reductase folA 0.0033
6642 Dihydrofolate reductase folA 0.0033
6756 Dihydrofolate reductase dfrA 0.0033
332 Beta-lactamase blaZ 0.0033
2478 Beta-lactamase ampC 0.0033
2613 Beta-lactamase ampC 0.0033
2635 Beta-lactamase ampC 0.0033
2700 Beta-lactamase penP 0.0033
5445 Beta-lactamase blaB 0.0033
6019 Beta-lactamase SHV-7 0.0033
6701 Beta-lactamase cphA 0.0033
3007 Carbonic anhydrase 12 CA12 0.0033
4205 Carbonic anhydrase 9 CA9 0.0033
2675 Pteridine reductase 1 PTR1 0.0032
2159 Quinone oxidoreductase CRYZ 0.0032
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0032
4784 Beta-mannosidase manB 0.0032
6695 Beta-mannosidase BT_0458 0.0032
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0032
1124 Sepiapterin reductase SPR 0.0032
634 Squalene monooxygenase SQLE 0.0031
7196 Squalene monooxygenase ERG1 0.0031
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0031
342 P protein [Includes: DNA-directed DNA polymerase P 0.0031
612 P protein [Includes: DNA-directed DNA polymerase P 0.0031
6042 Prostaglandin reductase 2 PTGR2 0.003
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.003
6031 Cytochrome P450 3A43 CYP3A43 0.0029
3688 Branched-chain-amino-acid aminotransferase ilvE 0.0028
4252 Penicillin-binding protein 5 dacA 0.0028
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0028
6103 Arylamine N-acetyltransferase 1 NAT1 0.0028
159 Penicillin-binding protein 2B penA 0.0028
6121 Penicillin-binding protein 2B penA 0.0028
2998 Sialic acid-binding Ig-like lectin 7 SIGLEC7 0.0028
1867 Major prion protein PRNP 0.0028
1792 Tissue-type plasminogen activator PLAT 0.0028
904 Glutathione S-transferase P GSTP1 0.0028
273 Apoptosis regulator Bcl-2 BCL2 0.0027
183 Vascular endothelial growth factor A VEGFA 0.0027
1025 Aquaporin-1 AQP1 0.0027
3685 Catabolite gene activator crp 0.0027
4655 Adenylate cyclase cyaC 0.0027
4759 Adenylate cyclase cyaB2 0.0027
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0026
293 Gamma-glutamyl hydrolase GGH 0.0026
4773 Deoxycytidine kinase DCK 0.0026
6146 High affinity copper uptake protein 1 SLC31A1 0.0026
427 Substance-P receptor TACR1 0.0025
509 Thymidine kinase TK 0.0025
570 Thymidine kinase TK 0.0025
2559 Thymidine kinase TK 0.0025
3430 Thymidine kinase tdk 0.0025
3518 Thymidine kinase TK 0.0025
5301 Thymidine kinase tdk 0.0025
5771 Thymidine kinase ORF36 0.0025
7009 Thymidine kinase ORF36 0.0025
4787 Envelope glycoprotein gp160 env 0.0025
4820 Envelope glycoprotein gp160 env 0.0025
5727 Envelope glycoprotein gp160 env 0.0025
707 72 kDa type IV collagenase MMP2 0.0025
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0025
4192 DNA topoisomerase 2-beta TOP2B 0.0025
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0024
6207 30S ribosomal protein S14 rpsN 0.0024
6209 30S ribosomal protein S19 rpsS 0.0024
6712 30S ribosomal protein S19 rpsS 0.0024
6726 30S ribosomal protein S19 rpsS 0.0024
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0024
3814 Complement C1r subcomponent C1R 0.0024
106 Cannabinoid receptor 2 CNR2 0.0024
471 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 0.0024
2297 Genome polyprotein Not Available 0.0024
2322 Genome polyprotein Not Available 0.0024
2694 Genome polyprotein Not Available 0.0024
2719 Genome polyprotein Not Available 0.0024
2860 Genome polyprotein Not Available 0.0024
2928 Genome polyprotein Not Available 0.0024
3160 Genome polyprotein Not Available 0.0024
3260 Genome polyprotein Not Available 0.0024
4783 Genome polyprotein Not Available 0.0024
5726 Genome polyprotein Not Available 0.0024
5779 Genome polyprotein Not Available 0.0024
5867 Genome polyprotein Not Available 0.0024
6253 Genome polyprotein Not Available 0.0024
6301 Genome polyprotein Not Available 0.0024
6380 Genome polyprotein Not Available 0.0024
6381 Genome polyprotein Not Available 0.0024
6437 Genome polyprotein Not Available 0.0024
6520 Genome polyprotein Not Available 0.0024
6521 Genome polyprotein Not Available 0.0024
6652 Genome polyprotein Not Available 0.0024
6734 Genome polyprotein Not Available 0.0024
6735 Genome polyprotein Not Available 0.0024
6736 Genome polyprotein Not Available 0.0024
6737 Genome polyprotein Not Available 0.0024
6738 Genome polyprotein Not Available 0.0024
6739 Genome polyprotein Not Available 0.0024
6744 Genome polyprotein Not Available 0.0024
6748 Genome polyprotein Not Available 0.0024
6894 Genome polyprotein Not Available 0.0024
6898 Genome polyprotein Not Available 0.0024
1629 Transcription factor AP-1 JUN 0.0024
2249 Aspartate aminotransferase aspC 0.0023
2671 Aspartate aminotransferase aspC 0.0023
5490 Aspartate aminotransferase Not Available 0.0023
68 Cannabinoid receptor 1 CNR1 0.0023
1313 Lactoylglutathione lyase GLO1 0.0023
6167 Organic solute transporter subunit beta OSTB 0.0023
4760 Mll3241 protein mll3241 0.0023
6166 Organic solute transporter subunit alpha OSTA 0.0023
2782 Complement C1s subcomponent C1S 0.0022
3480 Mannan endo-1,4-beta-mannosidase manA 0.0022
3426 Glutamine synthetase glnA 0.0021
3987 Glutamine synthetase GLUL 0.0021
1196 Complement decay-accelerating factor CD55 0.0021
3437 Eosinophil lysophospholipase CLC 0.0021
718 Folate receptor gamma FOLR3 0.0021
299 Folate receptor beta FOLR2 0.0021
804 Mitochondrial folate transporter/carrier SLC25A32 0.0021
1198 Serum paraoxonase/arylesterase 1 PON1 0.0021
6223 Penicillin-binding protein 1C pbpC 0.0021
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0021
527 Prostacyclin receptor PTGIR 0.0021
3817 Complement C1q subcomponent subunit C C1QC 0.0021
3815 Complement C1q subcomponent subunit A C1QA 0.0021
3816 Complement C1q subcomponent subunit B C1QB 0.0021
1102 Low affinity immunoglobulin gamma Fc region receptor III-B FCGR3B 0.0021
3818 Low affinity immunoglobulin gamma Fc region receptor III-A FCGR3A 0.0021
3819 Low affinity immunoglobulin gamma Fc region receptor II-a FCGR2A 0.0021
3821 Low affinity immunoglobulin gamma Fc region receptor II-c FCGR2C 0.0021
4604 Liver carboxylesterase 1 CES1 0.0021
3820 Low affinity immunoglobulin gamma Fc region receptor II-b FCGR2B 0.002
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.002
1039 Histone deacetylase 9 HDAC9 0.002
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.002
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.002
784 High affinity immunoglobulin gamma Fc receptor I FCGR1A 0.0019
867 Penicillin-binding protein 3 pbpC 0.0019
6119 Penicillin-binding protein 3 pbp3 0.0019
7154 Penicillin-binding protein 3 pbp3 0.0019
7157 Penicillin-binding protein 3 LMHCC_2184 0.0019
7162 Penicillin-binding protein 3 pbpB 0.0019
7172 Penicillin-binding protein 3 pbp3 0.0019
1654 Interleukin-1 beta IL1B 0.0019
260 Cytochrome P450 51 ERG11 0.0019
761 Cytochrome P450 51 ERG11 0.0019
3163 Cytochrome P450 51 cyp51 0.0019
2808 Chloramphenicol acetyltransferase 3 cat3 0.0019
891 Dihydropteroate synthase folP 0.0018
5359 Dihydropteroate synthase folP 0.0018
7175 Dihydropteroate synthase sulI 0.0018
468 Cytochrome P450 4A11 CYP4A11 0.0018
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0018
467 Delta-type opioid receptor OPRD1 0.0018
696 Kappa-type opioid receptor OPRK1 0.0017
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0017
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0017
2417 Chloramphenicol acetyltransferase cat 0.0017
3278 Chloramphenicol acetyltransferase cat 0.0017
2810 Dr hemagglutinin structural subunit draA 0.0017
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0017
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0017
2207 Rhodopsin RHO 0.0017
847 Mu-type opioid receptor OPRM1 0.0017
4103 Proteasome subunit beta type 2 PSMB2 0.0016
4102 Proteasome subunit beta type 5 PSMB5 0.0016
4101 Proteasome subunit beta type 1 PSMB1 0.0016
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.0016
1374 Natriuretic peptides B NPPB 0.0015
1827 Gap junction alpha-1 protein GJA1 0.0015
1908 Vascular cell adhesion protein 1 VCAM1 0.0015
494 Caspase-1 CASP1 0.0015
320 5-hydroxytryptamine 1A receptor HTR1A 0.0015
4785 Ig gamma-1 chain C region IGHG1 0.0015
1405 Thiopurine S-methyltransferase TPMT 0.0015
511 5-hydroxytryptamine 1F receptor HTR1F 0.0015
816 Biliverdin reductase A BLVRA 0.0015
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0015
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0015
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0015
810 Heme oxygenase 1 HMOX1 0.0014
3391 Heme oxygenase 1 pbsA1 0.0014
4217 Telomerase reverse transcriptase TERT 0.0014
3760 Penicillin-binding protein 5 precursor dacA 0.0014
528 5-hydroxytryptamine 1E receptor HTR1E 0.0014
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.0014
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.0014
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.0014
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.0014
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.0014
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.0014
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.0014
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.0014
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.0014
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.0014
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.0014
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.0014
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.0014
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.0014
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.0014
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.0014
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.0014
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.0014
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.0014
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.0014
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.0014
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.0014
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.0014
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.0014
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.0014
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.0014
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.0014
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.0014
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.0014
602 Acyl carrier protein, mitochondrial NDUFAB1 0.0014
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.0014
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.0014
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.0014
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.0014
644 Heme oxygenase 2 HMOX2 0.0014
4982 Heme oxygenase 2 pbsA2 0.0014
729 GDP-L-fucose synthetase TSTA3 0.0014
3463 GDP-L-fucose synthetase fcl 0.0014
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.0014
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.0014
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.0014
206 3-keto-steroid reductase HSD17B7 0.0014
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.0014
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.0014
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.0014
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.0014
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.0014
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.0014
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.0014
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.0014
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.0014
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.0014
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.0014
34 7-dehydrocholesterol reductase DHCR7 0.0014
662 Fatty aldehyde dehydrogenase ALDH3A2 0.0014
711 UDP-glucose 6-dehydrogenase UGDH 0.0014
3672 UDP-glucose 6-dehydrogenase hasB 0.0014
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.0014
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.0014
107 C-4 methylsterol oxidase SC4MOL 0.0014
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0014
3726 D-3-phosphoglycerate dehydrogenase serA 0.0014
4291 D-3-phosphoglycerate dehydrogenase serA 0.0014
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.0014
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.0014
167 L-lactate dehydrogenase C chain LDHC 0.0014
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.0014
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.0014
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.0014
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.0014
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.0014
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.0014
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.0014
643 Peroxisomal bifunctional enzyme EHHADH 0.0014
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.0014
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.0014
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.0014
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.0013
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0013
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0013
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0013
831 D(2) dopamine receptor DRD2 0.0013
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0013
396 Alcohol dehydrogenase 4 ADH4 0.0013
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.0013
328 Sorbitol dehydrogenase SORD 0.0013
597 Dihydropteridine reductase QDPR 0.0013
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0013
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0013
6184 D-alanyl-D-alanine carboxypeptidase dacC dacC 0.0013
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0013
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0013
857 Malate dehydrogenase, mitochondrial MDH2 0.0013
2077 Caspase-3 CASP3 0.0013
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0013
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0013
6020 Aldehyde oxidase AOX1 0.0013
12 Alcohol dehydrogenase class 3 ADH5 0.0013
77 L-lactate dehydrogenase B chain LDHB 0.0012
819 Penicillin-binding protein 4 dacB 0.0012
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.0012
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0012
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0012
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0012
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0012
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0012
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0012
473 L-lactate dehydrogenase A chain LDHA 0.0012
716 5-hydroxytryptamine 7 receptor HTR7 0.0012
6163 Copper-transporting ATPase 2 ATP7B 0.0012
6165 Copper-transporting ATPase 1 ATP7A 0.0012
556 Alpha-1A adrenergic receptor ADRA1A 0.0012
702 UMP-CMP kinase CMPK1 0.0012
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0011
1864 RET proto-oncogene RET 0.0011
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0011
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0011
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0011
13 Aminomethyltransferase, mitochondrial AMT 0.0011
6026 Alcohol dehydrogenase 6 ADH6 0.0011
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0011
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0011
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.0011
5756 D-alanyl-D-alanine carboxypeptidase dac 0.0011
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0011
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0011
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0011
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0011
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0011
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0011
627 11-cis retinol dehydrogenase RDH5 0.0011
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0011
626 Cysteine dioxygenase type 1 CDO1 0.0011
436 5-hydroxytryptamine 2B receptor HTR2B 0.0011
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0011
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0011
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0011
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0011
569 Retinal dehydrogenase 2 ALDH1A2 0.0011
611 Retinal dehydrogenase 1 ALDH1A1 0.0011
251 Alcohol dehydrogenase 1A ADH1A 0.001
725 5-hydroxytryptamine 1D receptor HTR1D 0.001
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.001
885 5-hydroxytryptamine 1B receptor HTR1B 0.001
997 Protein kinase C beta type PRKCB 0.001
896 Glutathione S-transferase Mu 1 GSTM1 0.001
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.001
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.001
1618 High affinity nerve growth factor receptor NTRK1 0.001
1970 Protein kinase C alpha type PRKCA 0.001
279 Tyrosinase TYR 0.001
6218 Pannexin-1 PANX1 0.001
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0009
714 Glutathione reductase, mitochondrial GSR 0.0009
2408 Tyrosine-protein kinase SYK SYK 0.0009
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0009
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0009
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0009
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0009
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0009
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0009
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0009
517 Alcohol dehydrogenase 1C ADH1C 0.0009
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0009
921 Glutamate receptor 2 GRIA2 0.0009
228 Beta platelet-derived growth factor receptor PDGFRB 0.0009
4943 Cytochrome c6 petJ 0.0009
4905 Cytochrome c2 Not Available 0.0009
4939 Cytochrome c2 cycA 0.0009
4964 Cytochrome c2 cycA 0.0009
4979 Cytochrome c2 cycA 0.0009
6673 Cytochrome c2 cycA 0.0009
4954 Soluble cytochrome b558 Not Available 0.0009
4984 Neuroglobin NGB 0.0009
4934 Cytochrome c-551 nirM 0.0009
5218 Cytochrome c-551 nirM 0.0009
4994 Hemoglobin-like protein HbO glbO 0.0009
4925 Cytochrome c-type protein SHP shp 0.0009
4947 Bacterial hemoglobin vhb 0.0009
4942 Diheme cytochrome c napB napB 0.0009
4998 Hemoglobin-like protein yjbI yjbI 0.0009
4916 Cyanoglobin glbN 0.0009
4915 Cytochrome c-550 psbV 0.0009
4959 Cytochrome c-550 psbV 0.0009
5216 Cytochrome c-550 psbV 0.0009
4961 Hemophore HasA hasA 0.0009
4975 Cytochrome c-556 RPA3973 0.0009
4936 Cytochrome c2 iso-2 Not Available 0.0009
4910 Cytoglobin CYGB 0.0008
4904 Cytochrome c family protein GSU1996 0.0008
4981 Iron-starvation protein PigA pigA 0.0008
4976 Apocytochrome f petA 0.0008
6407 Apocytochrome f petA 0.0008
3116 Bacterioferritin bfr 0.0008
4906 Bacterioferritin bfr 0.0008
4965 Bacterioferritin bfr 0.0008
5000 HemO hemO 0.0008
4907 Cytochrome c-L moxG 0.0008
6865 Cytochrome c-L moxG 0.0008
4909 CooA protein cooA 0.0008
4764 Cytochrome P450 165C4 CYP165C4 0.0008
4971 Nonaheme cytochrome c hmcA 0.0008
4989 Cytochrome c551 peroxidase ccp 0.0008
5222 Cytochrome c551 peroxidase ccpA 0.0008
4926 Heme-based aerotactic transducer hemAT hemAT 0.0008
4937 Cytochrome oxidase subunit II rcoxA 0.0008
4999 Cytochrome P450 165B3 CYP165B3 0.0008
4972 P450cin cinA 0.0008
4960 Putative cytochrome P450-family protein SCO7417 0.0008
4935 Cytochrome c-554 cycA1 0.0008
4931 Cytochrome P450 167A1 CYP167A1 0.0008
4993 Hydroxylamine oxidoreductase hao1 0.0008
4952 Catalase/peroxidase katA 0.0008
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0008
4922 Cytochrome c, putative SO_4144 0.0008
4903 Methyl-accepting chemotaxis protein Tar4 0.0008
3093 Catalase HPII katE 0.0008
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0008
1184 Interferon beta IFNB1 0.0008
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0008
5818 Folate receptor alpha FOLR1 0.0008
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0008
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0008
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0008
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0008
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0008
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0008
504 Mast/stem cell growth factor receptor KIT 0.0008
3587 Gastrotropin FABP6 0.0008
193 Beta-1 adrenergic receptor ADRB1 0.0008
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0007
766 Beta-2 adrenergic receptor ADRB2 0.0007
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0007
4666 Fucose-binding lectin PA-IIL lecB 0.0007
789 Alpha-1D adrenergic receptor ADRA1D 0.0007
2372 Bifunctional tail protein 9 0.0007
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0006
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0006
4920 Peroxidase/catalase katG 0.0006
4878 Glycoprotein hormones alpha chain CGA 0.0006
1052 Cytotoxic T-lymphocyte protein 4 CTLA4 0.0006
1072 Granzyme B GZMB 0.0006
4871 Endo-beta-N-acetylglucosaminidase F3 endOF3 0.0006
4880 Membrane cofactor protein CD46 0.0006
4889 Ig epsilon chain C region IGHE 0.0006
4877 Beta-mannanase man 0.0006
1563 Platelet glycoprotein Ib alpha chain GP1BA 0.0006
4850 Beta-2-glycoprotein 1 APOH 0.0006
4856 CD209 antigen CD209 0.0006
4189 Alpha-galactosidase A GLA 0.0006
4869 Major capsid protein A430L 0.0006
757 Fusion glycoprotein F0 F 0.0006
4875 Fusion glycoprotein F0 F 0.0006
4852 Reticulon-4 receptor RTN4R 0.0006
4845 ADAM 33 ADAM33 0.0006
1354 Beta-glucuronidase GUSB 0.0006
442 Envelope glycoprotein gp41 0.0006
4859 Envelope glycoprotein env 0.0006
4882 Dipeptidyl aminopeptidase-like protein 6 DPP6 0.0006
4721 Beta-1,4-mannanase manA 0.0006
3352 Structural polyprotein Not Available 0.0006
3628 Structural polyprotein Not Available 0.0006
4892 Structural polyprotein Not Available 0.0006
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0006
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0006
4037 Hypothetical protein GPX1 0.0006
4297 Hypothetical protein SP_1951 0.0006
4521 Hypothetical protein BC_2969 0.0006
4540 Hypothetical protein TM_1070 0.0006
4555 Hypothetical protein MT1739 0.0006
4569 Hypothetical protein mshD 0.0006
4578 Hypothetical protein PA3270 0.0006
4747 Hypothetical protein PA3967 0.0006
5177 Hypothetical protein TM_0096 0.0006
5194 Hypothetical protein PA1204 0.0006
5240 Hypothetical protein Rv2991 0.0006
5370 Hypothetical protein TM_1158 0.0006
5710 Hypothetical protein Tb927.5.1360 0.0006
4923 Cytochrome c3 DvMF_2499 0.0006
4945 Cytochrome c3 Not Available 0.0006
4949 Cytochrome c3 DVU_3171 0.0006
4968 Cytochrome c3 cytc3 0.0006
4997 Cytochrome c3 SO_2727 0.0006
5219 Cytochrome c3 cyd 0.0006
4948 Cytochrome c-553 Not Available 0.0006
2119 Cytochrome b5 CYB5A 0.0006
3189 High-molecular-weight cytochrome c hmcA 0.0006
4902 Nine-heme cytochrome c Ddes_2038 0.0006
4289 Cytochrome P450 TT_P0059 0.0006
6262 Cytochrome P450 staP 0.0006
4990 PpcA ppcA 0.0006
4992 Cytochrome c peroxidase Not Available 0.0006
3570 Cytochrome P450 152A1 cypC 0.0006
4988 Sulfite oxidase, mitochondrial SUOX 0.0006
2915 Sensor protein fixL fixL 0.0006
4944 Sensor protein fixL fixL 0.0006
3375 Acidic cytochrome c3 Not Available 0.0006
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0006
4385 Cytochrome c' Not Available 0.0006
4967 Cytochrome c' cycA 0.0006
5038 Cytochrome c' Not Available 0.0006
5223 Cytochrome c' cycP 0.0006
4813 Heme oxygenase hmuO 0.0006
5769 Heme oxygenase Not Available 0.0006
124 Histamine H2 receptor HRH2 0.0006
824 Sodium-dependent serotonin transporter SLC6A4 0.0006
2230 Catalase CAT 0.0006
3249 Catalase katA 0.0006
3625 Catalase katA 0.0006
4539 Catalase katA 0.0006
4941 Catalase katB 0.0006
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0006
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0006
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0006
3670 Soluble cytochrome b562 precursor cybC 0.0006
4193 Atrial natriuretic peptide clearance receptor NPR3 0.0006
793 T-cell surface antigen CD2 CD2 0.0006
4861 Interleukin-6 receptor alpha chain IL6R 0.0006
119 Carcinoembryonic antigen-related cell adhesion molecule 1 CEACAM1 0.0006
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0006
3837 Cytokine receptor common beta chain CSF2RB 0.0006
3411 Cytochrome P450 121 cyp121 0.0006
502 5-hydroxytryptamine 2A receptor HTR2A 0.0006
2617 Nitric oxide synthase oxygenase nos 0.0006
2701 Nitric oxide synthase oxygenase nos 0.0006
3291 Cytochrome c-552 cycA 0.0005
4927 Cytochrome c-552 nrfA 0.0005
4938 Cytochrome c-552 cycA 0.0005
4953 Cytochrome c-552 nrfA 0.0005
5217 Cytochrome c-552 cycM 0.0005
4386 Hemoglobin-like protein HbN glbN 0.0005
3102 Flavohemoprotein hmp 0.0005
4969 Flavohemoprotein hmp 0.0005
2430 Chondroitinase B cslB 0.0005
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0005
518 Peroxidase/catalase T katG 0.0005
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0005
3221 Cytochrome c4 cc4 0.0005
605 Fumarate reductase flavoprotein subunit frdA 0.0005
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0005
3673 Fumarate reductase flavoprotein subunit fccA 0.0005
4912 Fumarate reductase flavoprotein subunit ifcA 0.0005
6549 Fumarate reductase flavoprotein subunit frdA 0.0005
1379 Interleukin-12 subunit beta IL12B 0.0005
4890 Hemagglutinin HA 0.0005
6566 Hemagglutinin Not Available 0.0005
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0005
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0005
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0005
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0005
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0005
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0005
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0005
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0005
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0005
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0005
4857 Zinc-alpha-2-glycoprotein AZGP1 0.0005
6858 Inactive carboxylesterase 4 CES1P1 0.0005
4608 Putative cytochrome P450 SCO1207 0.0005
4963 Putative cytochrome P450 SCO2884 0.0005
6254 Putative cytochrome P450 SCO6998 0.0005
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0005
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0005
6120 Cation-independent mannose-6-phosphate receptor IGF2R 0.0005
18 High affinity immunoglobulin epsilon receptor subunit alpha FCER1A 0.0005
554 Low-density lipoprotein receptor LDLR 0.0004
852 Heparin cofactor 2 SERPIND1 0.0004
358 Cystathionine beta-synthase CBS 0.0004
693 Hemoglobin subunit beta HBB 0.0004
1859 Prostatic acid phosphatase ACPP 0.0004
595 Fibrinogen alpha chain FGA 0.0004
3140 Hemagglutinin-neuraminidase HN 0.0004
3609 Hemagglutinin-neuraminidase HN 0.0004
3444 Cyanovirin-N Not Available 0.0004
3258 Mannosyl-oligosaccharide alpha-1,2-mannosidase MSDC 0.0004
6268 Hydroxyacid oxidase 1 HAO1 0.0004
4509 Acetoin(diacetyl) reductase budC 0.0004
958 Insulin-like growth factor 1 receptor IGF1R 0.0004
3689 Endoglucanase A celA 0.0004
3009 Beta-glucanase Not Available 0.0004
5411 Slt-IIvB stxB2e 0.0004
5565 Inorganic polyphosphate/ATP-glucomannokinase ppgmk 0.0004
5563 Galectin-2 LGALS2 0.0004
1875 Pulmonary surfactant-associated protein D SFTPD 0.0004
5569 Endo-1,4-beta glucanase EngF engF 0.0004
5046 Ecotin eco 0.0004
3793 Aspartate ammonia-lyase aspA 0.0004
5554 D-galactose-binding periplasmic protein mglB 0.0004
3741 D-galactose-binding periplasmic protein precursor mglB 0.0004
5568 Endoglucanase C307 celC307 0.0004
5553 Endoglucanase E1 Acel_0614 0.0004
5562 Hexokinase Not Available 0.0004
3744 Endoglucanase SS precursor celS 0.0004
5570 Endoglucanase E-4 celD 0.0004
5559 Neopullulanase nplT 0.0004
4670 Cellulase B celB 0.0004
4668 Laminarinase TM_0024 0.0004
4667 BH0236 protein BH0236 0.0004
4671 Endoglucanase C cenC 0.0004
64 Neuraminidase NA 0.0004
641 Neuraminidase NA 0.0004
2676 Neuraminidase NA 0.0004
3026 Neuraminidase NA 0.0004
3519 Neuraminidase NA 0.0004
6007 Neuraminidase NA 0.0004
2577 Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase MAN1B1 0.0004
2298 Cytochrome P450-cam camC 0.0003
1243 Cathepsin D CTSD 0.0003
309 Antithrombin-III SERPINC1 0.0003
1782 Neutrophil gelatinase-associated lipocalin LCN2 0.0003
5176 YtnJ moxC 0.0003
5416 Coat protein VP1 Not Available 0.0003
2705 Dimethyl sulfoxide reductase dmsA 0.0003
5247 Endo-1,4-beta-xylanase Not Available 0.0003
5248 Endo-1,4-beta-xylanase xlnA 0.0003
5250 Endo-1,4-beta-xylanase xyl 0.0003
4669 Endo-1,4-beta-xylanase A xynA 0.0003
4715 Endo-1,4-beta-xylanase A xlnA 0.0003
5560 Endo-1,4-beta-xylanase A xynA 0.0003
1503 Galectin-7 LGALS7 0.0003
5498 Maltoporin lamB 0.0003
5561 Maltoporin lamB 0.0003
5056 Maltooligosyltrehalose trehalohydrolase, putative treZ 0.0003
3525 ADP-ribose pyrophosphatase, mitochondrial NUDT9 0.0003
4622 Amylase Not Available 0.0003
2728 Glucan 1,4-alpha-maltotetraohydrolase amyP 0.0003
6307 Ig gamma-2 chain C region IGHG2 0.0003
2826 Glucose--fructose oxidoreductase gfo 0.0003
1881 Hexokinase-1 HK1 0.0003
2581 Chondroitinase AC cslA 0.0003
6847 Lactase-phlorizin hydrolase LCT 0.0003
2324 Botulinum neurotoxin type B botB 0.0003
3153 Quinoprotein glucose dehydrogenase-B gdhB 0.0003
3747 Cellulase B precursor celB 0.0003
3547 Enterotoxin type B entB 0.0003
2856 Glucosamine-6-phosphate isomerase GNPDA1 0.0003
2564 Glucan 1,4-alpha-maltohexaosidase Not Available 0.0003
4819 Hydrolase Not Available 0.0003
5249 Hydrolase Not Available 0.0003
5436 Hydrolase Not Available 0.0003
2531 Alpha-amylase amyE 0.0003
2948 Alpha-amylase amy 0.0003
3169 Alpha-amylase Not Available 0.0003
2541 Neopullulanase 1 tvaI 0.0003
4811 Amylosucrase ams 0.0003
3091 Maltodextrin phosphorylase malP 0.0003
2606 Neopullulanase 2 tvaII 0.0003
4692 A/G-specific adenine glycosylase mutY 0.0003
3225 Shiga toxin B-chain stxB 0.0003
3365 Beta-amylase spoII 0.0003
4830 Aldose 1-epimerase galM 0.0003
6614 Lactase-like protein LCTL 0.0003
1675 Glucokinase GCK 0.0003
4662 Glucokinase glk 0.0003
3030 Salivary alpha-amylase AMY1A 0.0003
2293 Cyclomaltodextrin glucanotransferase Not Available 0.0003
2508 Cyclomaltodextrin glucanotransferase cgt 0.0003
2523 Cyclomaltodextrin glucanotransferase cgt 0.0003
3207 Cyclomaltodextrin glucanotransferase amyA 0.0003
4272 POSSIBLE CELLULASE CELA1 celA1 0.0003
2570 Tetanus toxin tetX 0.0002
2448 Exoglucanase/xylanase [Includes: Exoglucanase cex 0.0002
3668 Maltose-binding periplasmic protein precursor malE 0.0002
2802 Endoglucanase G celCCG 0.0002
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0002
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0002
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0002
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0002
2440 Endoglucanase F celCCF 0.0002
2245 Xylose isomerase xylA 0.0002
2253 Xylose isomerase xylA 0.0002
2260 Xylose isomerase xylA 0.0002
2431 Xylose isomerase xylA 0.0002
2252 Endoglucanase 5A cel5A 0.0002
10 Glycogen phosphorylase, liver form PYGL 0.0002
2723 Cholera enterotoxin subunit B ctxB 0.0002
952 Dipeptidyl peptidase 4 DPP4 0.0002
4513 Pancreatic alpha-amylase AMY2A 0.0002
2427 Ferrichrome-iron receptor fhuA 0.0002
1152 Glycogen phosphorylase, muscle form PYGM 0.0002
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