DT-Web

3-oxoacyl-[acyl-carrier-protein] synthase 1


Partner ID 889
Name 3-oxoacyl-[acyl-carrier-protein] synthase 1
Synonyms 2546
Gene name fabB
General function Lipid transport and metabolism
Specific function Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Specific for elongation from C-10 to unsaturated C-16 and C-18 fatty acids
Gene sequence + ...

ATGAAACGTGCAGTGATTACTGGCCTGGGCATTGTTTCCAGCATCGGTAATAACCAGCAGGAAGTCCTGGCATCTCTGCGTGAAGGACGTTCAGGGATCACTTTCTCTCAGGAGCTGAAGGATTCCGGCATGCGTAGCCACGTCTGGGGCAACGTAAAACTGGATACCACTGGCCTCATTGACCGCAAAGTTGTGCGCTTTATGAGCGACGCATCCATTTATGCATTCCTTTCTATGGAGCAGGCAATCGCTGATGCGGGCCTCTCTCCGGAAGCTTACCAGAATAACCCGCGCGTTGGCCTGATTGCAGGTTCCGGCGGCGGCTCCCCGCGTTTCCAGGTGTTCGGCGCTGACGCAATGCGCGGCCCGCGCGGCCTGAAAGCGGTTGGCCCGTATGTGGTCACCAAAGCGATGGCATCCGGCGTTTCTGCCTGCCTCGCCACCCCGTTTAAAATTCATGGCGTTAACTACTCCATCAGCTCCGCGTGTGCGACTTCCGCACACTGTATCGGTAACGCAGTAGAGCAGATCCAACTGGGCAAACAGGACATCGTGTTTGCTGGCGGCGGCGAAGAGCTGTGCTGGGAAATGGCTTGCGAATTCGACGCAATGGGTGCGCTGTCTACTAAATACAACGACACCCCGGAAAAAGCCTCCCGTACTTACGACGCTCACCGTGACGGTTTCGTTATCGCTGGCGGCGGCGGTATGGTAGTGGTTGAAGAGCTGGAACACGCGCTGGCGCGTGGTGCTCACATCTATGCTGAAATCGTTGGCTACGGCGCAACCTCTGATGGTGCAGACATGGTTGCTCCGTCTGGCGAAGGCGCAGTACGCTGCATGAAGATGGCGATGCATGGCGTTGATACCCCAATCGATTACCTGAACTCCCACGGTACTTCGACTCCGGTTGGCGACGTGAAAGAGCTGGCAGCTATCCGTGAAGTGTTCGGCGATAAGAGCCCGGCGATTTCTGCAACCAAAGCCATGACCGGTCACTCTCTGGGCGCTGCTGGCGTACAGGAAGCTATCTACTCTCTGCTGATGCTGGAACACGGCTTCATCGCCCCGAGCATCAACATTGAAGAGCTGGACGAGCAGGCTGCAGGTCTGAACATCGTGACCGAAACGACCGATCGCGAACTGACCACCGTTATGTCTAACAGCTTCGGCTTCGGCGGCACCAACGCCACGCTGGTAATGCGCAAGCTGAAAGATTAA
Protein sequence + ...

MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGMRSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLIAGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSISSACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKASRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEGAVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHSLGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGFGGTNATLVMRKLKD
GO Classification
function
catalytic activity
process
physiological process
metabolism
cellular metabolism
organic acid metabolism
carboxylic acid metabolism
fatty acid metabolism
fatty acid biosynthesis
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB01034 Cerulenin
DB03600 Decanoic Acid
DB04302 4-Hydroxy-3,5-Dimethyl-5-(2-Methyl-Buta-1,3-Dienyl)-5h-Thiophen-2-One
DB04519 Caprylic acid
DB08359 2-PHENYLAMINO-4-METHYL-5-ACETYL THIAZOLE
DB08627 (5R)-4-HYDROXY-3,5-DIMETHYL-5-[(1E,3E)-2-METHYLPENTA-1,3-DIENYL]THIOPHEN-2(5H)-ONE
DB08628 (5R)-5-[(1E)-BUTA-1,3-DIENYL]-4-HYDROXY-3,5-DIMETHYLTHIOPHEN-2(5H)-ONE

Associated as Prediction

Id Name
DB00070 Hyaluronidase
DB00091 Cyclosporine
DB00137 Xanthophyll
DB00139 Succinic acid
DB00140 Riboflavin
DB00158 Folic Acid
DB00168 Aspartame
DB00175 Pravastatin
DB00177 Valsartan
DB00181 Baclofen
DB00198 Oseltamivir
DB00228 Enflurane
DB00229 Cefotiam
DB00252 Phenytoin
DB00254 Doxycycline
DB00274 Cefmetazole
DB00279 Liothyronine
DB00286 Conjugated Estrogens
DB00300 Tenofovir
DB00311 Ethoxzolamide
DB00313 Valproic Acid
DB00316 Acetaminophen
DB00317 Gefitinib
DB00319 Piperacillin
DB00321 Amitriptyline
DB00328 Indomethacin
DB00334 Olanzapine
DB00345 Aminohippurate
DB00364 Sucralfate
DB00365 Grepafloxacin
DB00369 Cidofovir
DB00390 Digoxin
DB00412 Rosiglitazone
DB00415 Ampicillin
DB00430 Cefpiramide
DB00432 Trifluridine
DB00437 Allopurinol
DB00438 Ceftazidime
DB00446 Chloramphenicol
DB00451 Levothyroxine
DB00454 Meperidine
DB00456 Cefalotin
DB00459 Acitretin
DB00469 Tenoxicam
DB00472 Fluoxetine
DB00477 Chlorpromazine
DB00482 Celecoxib
DB00493 Cefotaxime
DB00495 Zidovudine
DB00500 Tolmetin
DB00501 Cimetidine
DB00512 Vancomycin
DB00520 Caspofungin
DB00529 Foscarnet
DB00530 Erlotinib
DB00536 Guanidine
DB00540 Nortriptyline
DB00544 Fluorouracil
DB00554 Piroxicam
DB00563 Methotrexate
DB00567 Cephalexin
DB00573 Fenoprofen
DB00576 Sulfamethizole
DB00577 Valaciclovir
DB00578 Carbenicillin
DB00583 L-Carnitine
DB00584 Enalapril
DB00586 Diclofenac
DB00595 Oxytetracycline
DB00605 Sulindac
DB00606 Cyclothiazide
DB00607 Nafcillin
DB00619 Imatinib
DB00624 Testosterone
DB00635 Prednisone
DB00649 Stavudine
DB00655 Estrone
DB00672 Chlorpropamide
DB00678 Losartan
DB00682 Warfarin
DB00688 Mycophenolate mofetil
DB00693 Fluorescein
DB00695 Furosemide
DB00703 Methazolamide
DB00709 Lamivudine
DB00712 Flurbiprofen
DB00717 Norethindrone
DB00718 Adefovir Dipivoxil
DB00731 Nateglinide
DB00743 Gadobenate Dimeglumine
DB00749 Etodolac
DB00753 Isoflurane
DB00759 Tetracycline
DB00762 Irinotecan
DB00776 Oxcarbazepine
DB00779 Nalidixic Acid
DB00783 Estradiol
DB00787 Acyclovir
DB00788 Naproxen
DB00798 Gentamicin
DB00802 Alfentanil
DB00812 Phenylbutazone
DB00815 Sodium lauryl sulfate
DB00818 Propofol
DB00819 Acetazolamide
DB00821 Carprofen
DB00827 Cinoxacin
DB00829 Diazepam
DB00861 Diflunisal
DB00863 Ranitidine
DB00864 Tacrolimus
DB00880 Chlorothiazide
DB00887 Bumetanide
DB00900 Didanosine
DB00903 Ethacrynic acid
DB00908 Quinidine
DB00912 Repaglinide
DB00917 Dinoprostone
DB00927 Famotidine
DB00931 Methacycline
DB00936 Salicyclic acid
DB00939 Meclofenamic acid
DB00943 Zalcitabine
DB00945 Acetylsalicylic acid
DB00946 Phenprocoumon
DB00995 Auranofin
DB00999 Hydrochlorothiazide
DB01004 Ganciclovir
DB01009 Ketoprofen
DB01015 Sulfamethoxazole
DB01016 Glyburide
DB01017 Minocycline
DB01032 Probenecid
DB01033 Mercaptopurine
DB01034 Cerulenin
DB01044 Gatifloxacin
DB01050 Ibuprofen
DB01051 Novobiocin
DB01053 Penicillin G
DB01056 Tocainide
DB01059 Norfloxacin
DB01060 Amoxicillin
DB01065 Melatonin
DB01068 Clonazepam
DB01082 Streptomycin
DB01083 Orlistat
DB01092 Ouabain
DB01098 Rosuvastatin
DB01120 Gliclazide
DB01124 Tolbutamide
DB01137 Levofloxacin
DB01140 Cefadroxil
DB01147 Cloxacillin
DB01159 Halothane
DB01160 Dinoprost Tromethamine
DB01165 Ofloxacin
DB01183 Naloxone
DB01189 Desflurane
DB01197 Captopril
DB01212 Ceftriaxone
DB01232 Saquinavir
DB01236 Sevoflurane
DB01237 Bromodiphenhydramine
DB01242 Clomipramine
DB01294 Bismuth Subsalicylate
DB01307 Insulin Detemir
DB01320 Fosphenytoin
DB01326 Cefamandole
DB01327 Cefazolin
DB01328 Cefonicid
DB01329 Cefoperazone
DB01330 Cefotetan
DB01333 Cefradine
DB01396 Digitoxin
DB01397 Magnesium salicylate
DB01414 Cefacetrile
DB01418 Acenocoumarol
DB01424 Aminophenazone
DB01435 Antipyrine
DB01581 Sulfamerazine
DB01582 Sulfamethazine
DB01583 Liotrix
DB01587 Ketazolam
DB01597 Cilastatin
DB01614 Acepromazine
DB01621 Pipotiazine
DB01622 Thioproperazine
DB01623 Thiothixene
DB01650 trans-2-hydroxycinnamic acid
DB01992 Coenzyme A
DB02039 S-Acetyl-Cysteine
DB02266 Flufenamic Acid
DB02315 Cyclic Guanosine Monophosphate
DB02316 1-(5-Carboxypentyl)-5-[(2,6-Dichlorobenzyl)Oxy]-1 H-Indole-2-Carboxylic Acid
DB02364 2-Amino-3-(Diethoxy-Phosphoryloxy)-Propionic Acid
DB02440 N-Octane
DB02527 Cyclic Adenosine Monophosphate
DB02659 Cholic Acid
DB02764 Hexane
DB03014 Heme
DB03193 Stearic acid
DB03203 Sphingosine
DB03553 Glutaric Acid
DB03585 Oxyphenbutazone
DB03600 Decanoic Acid
DB03661 Cysteinesulfonic Acid
DB03783 Phenacetin
DB03793 Benzoic Acid
DB03796 Palmitic Acid
DB03902 Oxalic Acid
DB04133 Degraded Cephaloridine
DB04224 Oleic Acid
DB04302 4-Hydroxy-3,5-Dimethyl-5-(2-Methyl-Buta-1,3-Dienyl)-5h-Thiophen-2-One
DB04348 Taurocholic Acid
DB04465 Lactose
DB04519 Caprylic acid
DB04524 Malonyl-Coenzyme A
DB04557 Arachidonic Acid
DB04574 Estropipate
DB04711 Iodipamide
DB04855 Dronedarone
DB05294 Vandetanib
DB05521 Telaprevir
DB05812 Abiraterone
DB06151 Acetylcysteine
DB06201 Rufinamide
DB06209 Prasugrel
DB06335 Saxagliptin
DB06705 Gadofosveset trisodium
DB06710 Methyltestosterone
DB06716 Fospropofol
DB07402 AZAPROPAZONE
DB07517 3-CARBOXY-4-METHYL-5-PROPYL-2-FURANPROPIONIC
DB07992 3-SULFOOXY-1H-INDOLE
DB08231 MYRISTIC ACID
DB08298 (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid
DB08359 2-PHENYLAMINO-4-METHYL-5-ACETYL THIAZOLE
DB08366 3-({3-[(1S,4aS,6S,7S,9S,9aR)-1,6-dimethyl-2-oxodecahydro-6,9-epoxy-4a,7-methanobenzo[7]annulen-1-yl]propanoyl}amino)-2,4-dihydroxybenzoic acid
DB08407 PLATENSIMYCIN
DB08627 (5R)-4-HYDROXY-3,5-DIMETHYL-5-[(1E,3E)-2-METHYLPENTA-1,3-DIENYL]THIOPHEN-2(5H)-ONE
DB08628 (5R)-5-[(1E)-BUTA-1,3-DIENYL]-4-HYDROXY-3,5-DIMETHYLTHIOPHEN-2(5H)-ONE
DB08735 4-HYDROXY-3-[(1S,3R)-3-HYDROXY-1-PHENYLBUTYL]-2H-CHROMEN-2-ONE
DB08736 4-HYDROXY-3-[(1S,3S)-3-HYDROXY-1-PHENYLBUTYL]-2H-CHROMEN-2-ONE
DB08820 Ivacaftor
DB08828 Vismodegib
DB08837 Tetraethylammonium
DB08846 Ellagic Acid
DB08860 Pitavastatin
DB08881 Vemurafenib
DB08893 Mirabegron
DB08899 Enzalutamide
DB08907 Canagliflozin
DB08912 Dabrafenib
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