DT-Web

DB00576 - Sulfamethizole


Identification
Name Sulfamethizole
Accession Number DB00576 (APRD00684)
Type small molecule
Description A sulfathiazole antibacterial agent. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 270.331
Groups approved
Monoisotopic Weight 270.024516964
Pharmacology
Indication For the treatment of urinary tract infection
Mechanism of action Sulfamethizole is a competitive inhibitor of bacterial enzyme dihydropteroate synthetase. The normal para-aminobenzoic acid (PABA) substrate is prevented from binding. The inhibited reaction is necessary in these organisms for the synthesis of folic acid.
Absorption Rapidly absorbed.
Protein binding 98-99%
Biotransformation Hepatic.
Route of elimination Not Available
Toxicity Not Available
Affected organisms
  • Enteric bacteria and other eubacteria
Interactions
Drug Interactions
Drug Mechanism of interaction
Chlorpropamide Sulfonamide/sulfonylurea: possible hypoglycemia
Fosphenytoin The sulfonamide increases the effect of hydantoin
Methenamine mandelate Possible crystallization of urates with this combination
Methotrexate The sulfamide increases the toxicity of methotrexate
Phenytoin The sulfonamide increases the effect of hydantoin
Food Interactions Not Available

Targets


Dihydropteroate synthase
Name Dihydropteroate synthase
Gene Name folP
Pharmacological action yes
Actions inhibitor
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Watanabe H, Hastings JW: Inhibition of bioluminescence in Photobacterium phosphoreum by sulfamethizole and its stimulation by thymine. Biochim Biophys Acta. 1990 Jun 26;1017(3):229-34. - Pubmed
DTHybrid score 0.8466

Enzymes


Cytochrome P450 2C9
Name Cytochrome P450 2C9
Gene Name CYP2C9
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.2967

Carriers


Predictions


Id Partner name Gene Name Score
5359 Dihydropteroate synthase folP 0.8466
7175 Dihydropteroate synthase sulI 0.8466
4512 Cytochrome P450 3A4 CYP3A4 0.1199
6016 Cytochrome P450 2C19 CYP2C19 0.1044
4924 Cytochrome P450 2C8 CYP2C8 0.101
4119 Cytochrome P450 2D6 CYP2D6 0.084
4200 Cytochrome P450 1A2 CYP1A2 0.0623
20 Prostaglandin G/H synthase 1 PTGS1 0.0605
1588 Multidrug resistance protein 1 ABCB1 0.0547
6030 Cytochrome P450 2B6 CYP2B6 0.053
6013 Cytochrome P450 2E1 CYP2E1 0.0455
4118 Cytochrome P450 3A5 CYP3A5 0.0395
290 Prostaglandin G/H synthase 2 PTGS2 0.0369
5718 Cytochrome P450 2A6 CYP2A6 0.0367
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0361
1729 Solute carrier family 22 member 6 SLC22A6 0.0343
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0297
6103 Arylamine N-acetyltransferase 1 NAT1 0.0283
6107 Cytochrome P450 3A7 CYP3A7 0.0263
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0244
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0215
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0207
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.02
6142 Solute carrier family 22 member 8 SLC22A8 0.0199
6102 Arylamine N-acetyltransferase 2 NAT2 0.0197
6024 Cytochrome P450 1A1 CYP1A1 0.0196
1389 Transforming growth factor beta-1 TGFB1 0.0169
1024 Solute carrier family 22 member 11 SLC22A11 0.0165
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.016
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0158
862 Multidrug resistance-associated protein 1 ABCC1 0.0155
2164 Multidrug resistance-associated protein 4 ABCC4 0.0154
6106 Cytochrome P450 2C18 CYP2C18 0.0149
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0147
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0147
6541 Peptostreptococcal albumin-binding protein pab 0.0142
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0139
6145 Solute carrier family 22 member 1 SLC22A1 0.0136
6143 Solute carrier family 22 member 7 SLC22A7 0.0136
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0129
502 5-hydroxytryptamine 2A receptor HTR2A 0.0127
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0121
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0119
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0112
492 Histamine H1 receptor HRH1 0.0109
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0108
136 Estrogen receptor ESR1 0.0105
70 Type-1 angiotensin II receptor AGTR1 0.0103
122 P2Y purinoceptor 12 P2RY12 0.0101
2211 Fatty acid-binding protein, heart FABP3 0.0098
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0096
831 D(2) dopamine receptor DRD2 0.0096
824 Sodium-dependent serotonin transporter SLC6A4 0.0096
566 Serotransferrin TF 0.0094
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0094
1898 Cytochrome P450 1B1 CYP1B1 0.0087
23 D(1A) dopamine receptor DRD1 0.0086
482 Glycine receptor subunit alpha-1 GLRA1 0.0085
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0084
6525 Group IID secretory phospholipase A2 PLA2G2D 0.008
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0077
118 Organic cation/carnitine transporter 2 SLC22A5 0.0076
183 Vascular endothelial growth factor A VEGFA 0.0076
320 5-hydroxytryptamine 1A receptor HTR1A 0.0076
6085 Fatty acid-binding protein, intestinal FABP2 0.0075
556 Alpha-1A adrenergic receptor ADRA1A 0.0075
756 Sex hormone-binding globulin SHBG 0.0075
3811 Cytochrome P450 19A1 CYP19A1 0.0074
537 ATP synthase delta chain, mitochondrial ATP5D 0.0072
543 Penicillin-binding protein 1B mrcB 0.0072
6186 Penicillin-binding protein 1B ponB 0.0072
6822 Penicillin-binding protein 1b pbp1b 0.0072
6844 Penicillin-binding protein 1b pbp1b 0.0072
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0072
632 Alpha-1B adrenergic receptor ADRA1B 0.0072
1 Peptidoglycan synthetase ftsI ftsI 0.0071
4155 Peptidoglycan synthetase ftsI ftsI 0.0071
645 Penicillin-binding protein 1A mrcA 0.0071
5805 Penicillin-binding protein 1A ponA 0.0071
6185 Penicillin-binding protein 1A mrcA 0.0071
6799 Penicillin-binding protein 1A pbpA 0.0071
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.007
776 Bile salt export pump ABCB11 0.0069
2853 14 kDa fatty acid-binding protein Not Available 0.0068
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0067
705 Glutamate receptor 1 GRIA1 0.0067
36 Insulin receptor INSR 0.0066
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0066
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0064
1119 Peroxiredoxin-5, mitochondrial PRDX5 0.0063
133 Dihydropterate synthase sulI 0.0063
4604 Liver carboxylesterase 1 CES1 0.0062
4116 Dihydropteroate synthetase Not Available 0.0062
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0062
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0062
341 5-hydroxytryptamine 3 receptor HTR3A 0.0062
146 Androgen receptor AR 0.0061
731 HIV-1 protease HIV-1 protease 0.006
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.006
6144 Solute carrier family 22 member 2 SLC22A2 0.0059
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0059
6141 Sodium/bile acid cotransporter SLC10A1 0.0059
738 Monocarboxylate transporter 1 SLC16A1 0.0058
2183 Fatty acid-binding protein, adipocyte FABP4 0.0058
847 Mu-type opioid receptor OPRM1 0.0057
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0057
811 Translocator protein TSPO 0.0056
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0056
696 Kappa-type opioid receptor OPRK1 0.0055
558 Solute carrier family 12 member 1 SLC12A1 0.0055
844 Epidermal growth factor receptor EGFR 0.0055
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0055
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0055
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0054
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0054
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0054
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0053
459 Retinoic acid receptor RXR-alpha RXRA 0.0053
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0053
590 5-hydroxytryptamine 2C receptor HTR2C 0.0052
373 Transthyretin TTR 0.0051
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.005
274 Muscarinic acetylcholine receptor M5 CHRM5 0.005
6027 Alkaline phosphatase, tissue-nonspecific isozyme ALPL 0.005
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0049
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0049
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0048
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0048
6184 D-alanyl-D-alanine carboxypeptidase dacC dacC 0.0048
6136 Multidrug resistance-associated protein 5 ABCC5 0.0048
3941 Amine oxidase [flavin-containing] A MAOA 0.0048
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0047
3382 Glycolipid transfer protein GLTP 0.0046
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0046
3810 Catechol O-methyltransferase COMT 0.0046
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0046
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0045
527 Prostacyclin receptor PTGIR 0.0045
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0045
467 Delta-type opioid receptor OPRD1 0.0045
115 Penicillin-binding protein 2 mrdA 0.0044
6069 Penicillin-binding protein 2 mrdA 0.0044
6118 Penicillin-binding protein 2 penA 0.0044
6187 Penicillin-binding protein 2 pbpA 0.0044
6686 Penicillin-binding protein 2 pbp2 0.0044
6939 Penicillin-binding protein 2 mrdA 0.0044
7163 Penicillin-binding protein 2 pbpA 0.0044
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0044
465 Calmodulin CALM1 0.0044
713 Sodium-dependent dopamine transporter SLC6A3 0.0044
49 Endothelin B receptor EDNRB 0.0044
5645 DNA topoisomerase 4 subunit B parE 0.0044
6227 DNA topoisomerase 4 subunit B parE 0.0044
887 DNA gyrase subunit B gyrB 0.0044
4150 DNA gyrase subunit B gyrB 0.0044
6225 DNA gyrase subunit B gyrB 0.0044
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0043
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0043
578 Endothelin-1 receptor EDNRA 0.0041
6147 Solute carrier family 22 member 3 SLC22A3 0.0041
3939 Amine oxidase [flavin-containing] B MAOB 0.0041
404 DNA gyrase subunit A gyrA 0.004
6224 DNA gyrase subunit A gyrA 0.004
477 DNA topoisomerase 4 subunit A parC 0.004
886 DNA topoisomerase 4 subunit A parC 0.004
6226 DNA topoisomerase 4 subunit A parC 0.004
318 Alpha-2A adrenergic receptor ADRA2A 0.004
6508 Putative uncharacterized protein srtB 0.004
6543 Putative uncharacterized protein tcp14 0.004
6615 Putative uncharacterized protein MT0785 0.004
6623 Putative uncharacterized protein Not Available 0.004
6806 Putative uncharacterized protein AGR_C_2535 0.004
6813 Putative uncharacterized protein SAV4671 0.004
6815 Putative uncharacterized protein AFE_1514 0.004
6819 Putative uncharacterized protein RUMGNA_03254 0.004
6825 Putative uncharacterized protein CV_3270 0.004
4161 Furin FURIN 0.004
468 Cytochrome P450 4A11 CYP4A11 0.004
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0039
6067 Penicillin binding protein 2a mecA 0.0038
24 Thymidylate synthase TMP1 0.0038
359 Thymidylate synthase TYMS 0.0038
2626 Thymidylate synthase thyA 0.0038
2729 Thymidylate synthase thyA 0.0038
5352 Thymidylate synthase THYA 0.0038
6031 Cytochrome P450 3A43 CYP3A43 0.0038
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0038
780 Retinoic acid receptor RXR-gamma RXRG 0.0038
869 Estrogen receptor beta ESR2 0.0037
260 Cytochrome P450 51 ERG11 0.0037
761 Cytochrome P450 51 ERG11 0.0037
3163 Cytochrome P450 51 cyp51 0.0037
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0037
130 Prostacyclin synthase PTGIS 0.0037
295 Carbonic anhydrase 1 CA1 0.0036
6137 Multidrug resistance-associated protein 6 ABCC6 0.0036
365 Dihydrofolate reductase DHFR 0.0036
2381 Dihydrofolate reductase DFR1 0.0036
2833 Dihydrofolate reductase Not Available 0.0036
2931 Dihydrofolate reductase folA 0.0036
3544 Dihydrofolate reductase folA 0.0036
3682 Dihydrofolate reductase folA 0.0036
6642 Dihydrofolate reductase folA 0.0036
6756 Dihydrofolate reductase dfrA 0.0036
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0036
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0036
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0036
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0036
819 Penicillin-binding protein 4 dacB 0.0036
357 Carbonic anhydrase 2 CA2 0.0036
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0036
1275 Estrogen sulfotransferase SULT1E1 0.0036
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0035
592 Carbonic anhydrase 4 CA4 0.0035
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0035
88 Retinoic acid receptor RXR-beta RXRB 0.0035
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0035
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0035
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0034
380 Cytochrome P450 17A1 CYP17A1 0.0033
2178 Metabotropic glutamate receptor 5 GRM5 0.0033
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0033
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0033
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0033
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0033
789 Alpha-1D adrenergic receptor ADRA1D 0.0032
594 Thyroxine-binding globulin SERPINA7 0.0032
6677 Myelin P2 protein PMP2 0.0032
6149 Solute carrier family 22 member 10 SLC22A10 0.0032
595 Fibrinogen alpha chain FGA 0.0032
3923 Cholinesterase BCHE 0.0031
275 Arachidonate 5-lipoxygenase ALOX5 0.0031
1227 Cytochrome b MT-CYB 0.0031
6386 Cytochrome b petB 0.0031
6937 Cytochrome b MT-CYB 0.0031
674 Dihydroorotate dehydrogenase homolog, mitochondrial PFF0160c 0.0031
766 Beta-2 adrenergic receptor ADRB2 0.0031
3760 Penicillin-binding protein 5 precursor dacA 0.0031
758 Thyroid hormone receptor alpha THRA 0.003
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.003
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.003
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.003
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.003
3813 Fibrinogen gamma chain FGG 0.0029
3812 Fibrinogen beta chain [Contains: Fibrinopeptide B] FGB 0.0029
614 Progesterone receptor PGR 0.0029
3932 Glutathione S-transferase A2 GSTA2 0.0029
1757 Myeloperoxidase MPO 0.0029
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0029
6033 High affinity interleukin-8 receptor A CXCR1 0.0029
6043 Putative G-protein coupled receptor 44 GPR44 0.0029
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0029
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0029
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0028
1656 CYP2B protein CYP2B 0.0028
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0028
1278 Pro-epidermal growth factor EGF 0.0028
1200 AMBP protein AMBP 0.0028
3866 Serum amyloid A protein SAA1 0.0028
1932 Apolipoprotein E APOE 0.0028
2981 Phospholipase A2, membrane associated PLA2G2A 0.0027
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0027
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0027
3639 Thymidine phosphorylase deoA 0.0027
3936 Thymidine phosphorylase TYMP 0.0027
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0027
346 Thyroid hormone receptor beta-1 THRB 0.0027
2159 Quinone oxidoreductase CRYZ 0.0027
1992 Vitamin D-binding protein GC 0.0027
889 3-oxoacyl-[acyl-carrier-protein] synthase 1 fabB 0.0027
6860 3-oxoacyl-[acyl-carrier-protein] synthase 1 kasA 0.0027
54 Prothrombin F2 0.0026
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0026
571 Melatonin receptor type 1A MTNR1A 0.0026
362 Melatonin receptor type 1B MTNR1B 0.0026
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0026
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0026
817 DNA topoisomerase 2-alpha TOP2A 0.0026
6126 Carbonic anhydrase 7 CA7 0.0026
427 Substance-P receptor TACR1 0.0025
1050 Bile salt sulfotransferase SULT2A1 0.0025
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0025
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0025
4252 Penicillin-binding protein 5 dacA 0.0025
504 Mast/stem cell growth factor receptor KIT 0.0025
1541 Metalloproteinase mmp20 0.0025
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0025
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0024
1618 High affinity nerve growth factor receptor NTRK1 0.0024
6148 Multidrug resistance-associated protein 7 ABCC10 0.0024
1867 Major prion protein PRNP 0.0024
159 Penicillin-binding protein 2B penA 0.0024
6121 Penicillin-binding protein 2B penA 0.0024
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0024
6231 Pepsin A PGA3 0.0024
436 5-hydroxytryptamine 2B receptor HTR2B 0.0024
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0024
633 Penicillin-binding proteins 1A/1B pbpA 0.0024
332 Beta-lactamase blaZ 0.0023
2478 Beta-lactamase ampC 0.0023
2613 Beta-lactamase ampC 0.0023
2635 Beta-lactamase ampC 0.0023
2700 Beta-lactamase penP 0.0023
5445 Beta-lactamase blaB 0.0023
6019 Beta-lactamase SHV-7 0.0023
6701 Beta-lactamase cphA 0.0023
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0023
94 5-hydroxytryptamine 4 receptor HTR4 0.0023
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0023
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0023
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0023
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0023
6182 Cytochrome P450 2J2 CYP2J2 0.0023
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0023
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0023
5934 Cytochrome P450 26A1 CYP26A1 0.0023
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0023
5787 Angiopoietin-1 receptor TEK 0.0023
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0022
629 Alpha-2B adrenergic receptor ADRA2B 0.0022
1525 Heparin-binding growth factor 2 FGF2 0.0022
4209 ATP-sensitive inward rectifier potassium channel 8 KCNJ8 0.0022
6014 Cytochrome P450 2A13 CYP2A13 0.0022
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0022
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0022
407 Vascular endothelial growth factor receptor 2 KDR 0.0021
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0021
707 72 kDa type IV collagenase MMP2 0.0021
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0021
4210 Toll-like receptor 4 TLR4 0.0021
4203 Histamine N-methyltransferase HNMT 0.0021
6209 30S ribosomal protein S19 rpsS 0.0021
6712 30S ribosomal protein S19 rpsS 0.0021
6726 30S ribosomal protein S19 rpsS 0.0021
6207 30S ribosomal protein S14 rpsN 0.0021
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0021
331 Retinol-binding protein I, cellular RBP1 0.0021
6501 Fatty acid-binding protein, liver FABP1 0.002
768 FK506-binding protein 1A FKBP1A 0.002
153 Dopamine beta-hydroxylase DBH 0.002
6220 Aryl hydrocarbon receptor AHR 0.002
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.002
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0019
162 Retinoic acid receptor gamma-1 RARG 0.0019
833 Organic cation/carnitine transporter 1 SLC22A4 0.0019
2207 Rhodopsin RHO 0.0019
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0019
1517 Beta-3 adrenergic receptor ADRB3 0.0019
777 Tumor necrosis factor TNF 0.0019
3426 Glutamine synthetase glnA 0.0019
3987 Glutamine synthetase GLUL 0.0019
65 Matrix metalloproteinase-9 Not Available 0.0018
4226 Uridine phosphorylase 2 UPP2 0.0018
199 Monocarboxylate transporter 8 SLC16A2 0.0018
4217 Telomerase reverse transcriptase TERT 0.0018
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0018
228 Beta platelet-derived growth factor receptor PDGFRB 0.0018
3312 Fatty acid-binding protein, brain FABP7 0.0018
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0018
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0018
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0018
1198 Serum paraoxonase/arylesterase 1 PON1 0.0018
6223 Penicillin-binding protein 1C pbpC 0.0018
1714 Mitogen-activated protein kinase 3 MAPK3 0.0017
4225 Uridine phosphorylase 1 UPP1 0.0017
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0017
1144 Hepatocyte growth factor receptor MET 0.0017
1291 cAMP response element-binding protein CREB1 0.0017
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0017
229 Retinoic acid receptor beta RARB 0.0017
992 Protein tyrosine kinase 2 beta PTK2B 0.0017
885 5-hydroxytryptamine 1B receptor HTR1B 0.0017
193 Beta-1 adrenergic receptor ADRB1 0.0017
871 Glucocorticoid receptor NR3C1 0.0017
3917 Methylenetetrahydrofolate reductase MTHFR 0.0017
730 Retinoic acid receptor alpha RARA 0.0017
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0016
3616 Fatty acid-binding protein, epidermal FABP5 0.0016
5431 Lipid binding protein Not Available 0.0016
413 Amidophosphoribosyltransferase PPAT 0.0016
2515 Amidophosphoribosyltransferase purF 0.0016
3714 Amidophosphoribosyltransferase purF 0.0016
5433 UPF0230 protein TM_1468 TM_1468 0.0016
5430 Hepatocyte nuclear factor 4-gamma HNF4G 0.0016
244 Angiotensin-converting enzyme ACE 0.0016
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0016
33 Cystine/glutamate transporter SLC7A11 0.0016
1648 Elastin ELN 0.0015
2021 Thrombomodulin THBD 0.0015
528 5-hydroxytryptamine 1E receptor HTR1E 0.0015
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0015
4120 NADPH--cytochrome P450 reductase POR 0.0015
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0015
273 Apoptosis regulator Bcl-2 BCL2 0.0015
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0015
208 DNA-directed RNA polymerase beta' chain rpoC 0.0015
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0015
2320 Thymidine kinase, cytosolic TK1 0.0015
3611 Cytidine deaminase cdd 0.0014
3707 Cytidine deaminase cdd 0.0014
4211 Cytidine deaminase CDA 0.0014
1010 Cytochrome P450 51A1 CYP51A1 0.0014
378 Alpha-2C adrenergic receptor ADRA2C 0.0014
638 D(3) dopamine receptor DRD3 0.0014
432 D(4) dopamine receptor DRD4 0.0014
1864 RET proto-oncogene RET 0.0014
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0014
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0014
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0014
921 Glutamate receptor 2 GRIA2 0.0014
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0014
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0014
2232 Interleukin-5 IL5 0.0014
1593 Mucin-2 MUC2 0.0014
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0014
518 Peroxidase/catalase T katG 0.0013
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0013
1268 Neuropeptide S receptor NPSR1 0.0013
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0013
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0013
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0013
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0013
6151 Monocarboxylate transporter 10 SLC16A10 0.0013
716 5-hydroxytryptamine 7 receptor HTR7 0.0013
283 SEC14-like protein 2 SEC14L2 0.0013
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0013
6218 Pannexin-1 PANX1 0.0013
6459 Glycodelin PAEP 0.0013
823 Fibroblast growth factor receptor 2 FGFR2 0.0013
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0013
6432 Transporter snf 0.0013
904 Glutathione S-transferase P GSTP1 0.0013
1405 Thiopurine S-methyltransferase TPMT 0.0013
822 Aldose reductase AKR1B1 0.0012
6073 Potassium channel subfamily K member 9 KCNK9 0.0012
6072 Potassium channel subfamily K member 3 KCNK3 0.0012
124 Histamine H2 receptor HRH2 0.0012
3937 Fatty-acid amide hydrolase FAAH 0.0012
29 Tubulin beta-1 chain TUBB1 0.0012
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0012
725 5-hydroxytryptamine 1D receptor HTR1D 0.0012
474 Acetylcholinesterase ACHE 0.0011
164 Histamine H4 receptor HRH4 0.0011
6042 Prostaglandin reductase 2 PTGR2 0.0011
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0011
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0011
1123 Eosinophil cationic protein RNASE3 0.0011
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0011
106 Cannabinoid receptor 2 CNR2 0.0011
1792 Tissue-type plasminogen activator PLAT 0.0011
1629 Transcription factor AP-1 JUN 0.0011
6174 50S ribosomal protein L32 rpmF 0.0011
4238 50S ribosomal protein L4 rplD 0.0011
5578 50S ribosomal protein L4 rplD 0.0011
6173 50S ribosomal protein L4 rplD 0.0011
6219 50S ribosomal protein L4 rplD 0.0011
6100 BDNF/NT-3 growth factors receptor NTRK2 0.001
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.001
1196 Complement decay-accelerating factor CD55 0.001
3809 Estrogen-related receptor gamma ESRRG 0.001
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.001
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.001
5756 D-alanyl-D-alanine carboxypeptidase dac 0.001
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.001
6146 High affinity copper uptake protein 1 SLC31A1 0.001
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.001
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.001
68 Cannabinoid receptor 1 CNR1 0.001
563 Thyroid peroxidase TPO 0.001
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.001
6138 Multidrug resistance protein 3 ABCB4 0.001
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.001
4122 Histone deacetylase 2 HDAC2 0.001
16 Adenosine A1 receptor ADORA1 0.001
1178 Adenosine A2a receptor ADORA2A 0.001
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.001
634 Squalene monooxygenase SQLE 0.0009
7196 Squalene monooxygenase ERG1 0.0009
1353 DNA topoisomerase 1 TOP1 0.0009
3552 DNA topoisomerase 1 topA 0.0009
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0009
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0009
4948 Cytochrome c-553 Not Available 0.0009
4923 Cytochrome c3 DvMF_2499 0.0009
4945 Cytochrome c3 Not Available 0.0009
4949 Cytochrome c3 DVU_3171 0.0009
4968 Cytochrome c3 cytc3 0.0009
4997 Cytochrome c3 SO_2727 0.0009
5219 Cytochrome c3 cyd 0.0009
4902 Nine-heme cytochrome c Ddes_2038 0.0009
3189 High-molecular-weight cytochrome c hmcA 0.0009
163 D(1B) dopamine receptor DRD5 0.0009
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0009
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0009
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0009
233 Potassium channel subfamily K member 2 KCNK2 0.0009
1341 Histamine H3 receptor HRH3 0.0009
2808 Chloramphenicol acetyltransferase 3 cat3 0.0009
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0009
84 Nuclear receptor 0B1 NR0B1 0.0009
1192 Sulfotransferase 1A1 SULT1A1 0.0009
1313 Lactoylglutathione lyase GLO1 0.0009
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0009
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0009
1256 5-hydroxytryptamine 6 receptor HTR6 0.0009
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0009
3808 Dihydropteroate synthase 2 folP2 0.0008
3601 Dihydropteroate synthase 1 folP1 0.0008
3807 Dihydropteroate synthase 1 folP1 0.0008
489 Monocarboxylate transporter 2 SLC16A7 0.0008
2417 Chloramphenicol acetyltransferase cat 0.0008
3278 Chloramphenicol acetyltransferase cat 0.0008
2810 Dr hemagglutinin structural subunit draA 0.0008
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0008
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0008
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0008
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0008
4386 Hemoglobin-like protein HbN glbN 0.0008
26 Vascular endothelial growth factor receptor 3 FLT4 0.0008
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0008
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0008
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0008
581 Cytochrome P450 2R1 CYP2R1 0.0008
32 Vascular endothelial growth factor receptor 1 FLT1 0.0008
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0008
3830 Calreticulin CALR 0.0008
4773 Deoxycytidine kinase DCK 0.0008
161 Tubulin beta chain TUBB 0.0008
312 Tubulin beta chain TUB2 0.0008
3221 Cytochrome c4 cc4 0.0007
319 Opioid receptor, sigma 1 OPRS1 0.0007
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0007
5818 Folate receptor alpha FOLR1 0.0007
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0007
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0007
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0007
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0007
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0007
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0007
737 Mineralocorticoid receptor NR3C2 0.0007
6034 Hydroxyindole O-methyltransferase ASMT 0.0007
6035 Nuclear receptor ROR-beta RORB 0.0007
6036 Eosinophil peroxidase EPX 0.0007
976 Platelet glycoprotein IX GP9 0.0007
1630 Integrin beta-2 ITGB2 0.0007
4103 Proteasome subunit beta type 2 PSMB2 0.0007
4102 Proteasome subunit beta type 5 PSMB5 0.0007
4101 Proteasome subunit beta type 1 PSMB1 0.0007
1374 Natriuretic peptides B NPPB 0.0007
1827 Gap junction alpha-1 protein GJA1 0.0007
1908 Vascular cell adhesion protein 1 VCAM1 0.0007
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0007
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0007
3947 Xanthine dehydrogenase/oxidase XDH 0.0007
814 Ryanodine receptor 1 RYR1 0.0007
511 5-hydroxytryptamine 1F receptor HTR1F 0.0006
239 Coagulation factor X F10 0.0006
7 Nitric oxide synthase, inducible NOS2 0.0006
293 Gamma-glutamyl hydrolase GGH 0.0006
1507 Cytochrome c CYCS 0.0006
251 Alcohol dehydrogenase 1A ADH1A 0.0006
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0006
174 Sigma 1-type opioid receptor SIGMAR1 0.0006
765 Indoleamine 2,3-dioxygenase IDO1 0.0006
6048 Troponin C, skeletal muscle TNNC2 0.0006
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0006
719 Retinoic acid receptor responder protein 1 RARRES1 0.0006
770 Retinoic acid-induced protein 3 GPRC5A 0.0006
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0006
820 Glycine receptor subunit alpha-2 GLRA2 0.0006
268 Adenosine A2b receptor ADORA2B 0.0006
828 Phenylalanine-4-hydroxylase PAH 0.0006
3109 Phenylalanine-4-hydroxylase phhA 0.0006
1650 Heme carrier protein 1 SLC46A1 0.0006
6044 Serum paraoxonase/lactonase 3 PON3 0.0006
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0006
5221 Cytochrome c3, 13 kDa Not Available 0.0006
3152 Cytochrome c'' cycA 0.0006
5220 Split-Soret cytochrome c Ddes_2150 0.0006
3700 Cytochrome c-552 precursor nrfA 0.0006
444 Alcohol dehydrogenase 1B ADH1B 0.0005
856 Vitamin D3 receptor VDR 0.0005
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0005
572 Integrin alpha-L ITGAL 0.0005
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0005
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0005
6743 Non-fluorescent flavoprotein luxF 0.0005
6753 Apolipoprotein M APOM 0.0005
2528 Fatty acid metabolism regulator protein fadR 0.0005
6740 Fatty acid metabolism regulator protein fadR 0.0005
6752 Guanylyl cyclase-activating protein 1 GUCA1A 0.0005
394 Calcineurin subunit B isoform 1 PPP3R1 0.0005
6742 Recoverin RCVRN 0.0005
6747 Chalcone/stilbene synthase family protein MT1417 0.0005
6741 Peroxisomal 3,2-trans-enoyl-CoA isomerase PECI 0.0005
6522 Hepatocyte nuclear factor 4-alpha HNF4A 0.0005
6751 Gag polyprotein gag 0.0005
6746 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform PPP3CA 0.0005
6749 Polyprotein Not Available 0.0005
5924 Microtubule-associated protein 4 MAP4 0.0005
5923 Microtubule-associated protein tau MAPT 0.0005
5798 Mitogen-activated protein kinase 11 MAPK11 0.0005
267 Plasminogen activator inhibitor 1 SERPINE1 0.0005
569 Retinal dehydrogenase 2 ALDH1A2 0.0005
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0005
1852 Microtubule-associated protein 2 MAP2 0.0005
611 Retinal dehydrogenase 1 ALDH1A1 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0005
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0005
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0005
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0005
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0005
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0005
517 Alcohol dehydrogenase 1C ADH1C 0.0005
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0005
5961 Insulin INS 0.0005
4954 Soluble cytochrome b558 Not Available 0.0005
4943 Cytochrome c6 petJ 0.0005
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0005
4916 Cyanoglobin glbN 0.0005
5000 HemO hemO 0.0005
4947 Bacterial hemoglobin vhb 0.0005
4934 Cytochrome c-551 nirM 0.0005
5218 Cytochrome c-551 nirM 0.0005
4942 Diheme cytochrome c napB napB 0.0005
4981 Iron-starvation protein PigA pigA 0.0005
4975 Cytochrome c-556 RPA3973 0.0005
4984 Neuroglobin NGB 0.0005
4994 Hemoglobin-like protein HbO glbO 0.0005
4905 Cytochrome c2 Not Available 0.0005
4939 Cytochrome c2 cycA 0.0005
4964 Cytochrome c2 cycA 0.0005
4979 Cytochrome c2 cycA 0.0005
6673 Cytochrome c2 cycA 0.0005
4935 Cytochrome c-554 cycA1 0.0005
4915 Cytochrome c-550 psbV 0.0005
4959 Cytochrome c-550 psbV 0.0005
5216 Cytochrome c-550 psbV 0.0005
4925 Cytochrome c-type protein SHP shp 0.0005
4998 Hemoglobin-like protein yjbI yjbI 0.0005
4910 Cytoglobin CYGB 0.0005
4936 Cytochrome c2 iso-2 Not Available 0.0005
4909 CooA protein cooA 0.0005
4961 Hemophore HasA hasA 0.0005
3116 Bacterioferritin bfr 0.0005
4906 Bacterioferritin bfr 0.0005
4965 Bacterioferritin bfr 0.0005
644 Heme oxygenase 2 HMOX2 0.0005
4982 Heme oxygenase 2 pbsA2 0.0005
4937 Cytochrome oxidase subunit II rcoxA 0.0005
4971 Nonaheme cytochrome c hmcA 0.0005
4907 Cytochrome c-L moxG 0.0005
6865 Cytochrome c-L moxG 0.0005
4903 Methyl-accepting chemotaxis protein Tar4 0.0005
4931 Cytochrome P450 167A1 CYP167A1 0.0005
4989 Cytochrome c551 peroxidase ccp 0.0005
5222 Cytochrome c551 peroxidase ccpA 0.0005
4976 Apocytochrome f petA 0.0005
6407 Apocytochrome f petA 0.0005
4904 Cytochrome c family protein GSU1996 0.0005
4764 Cytochrome P450 165C4 CYP165C4 0.0005
4922 Cytochrome c, putative SO_4144 0.0005
4999 Cytochrome P450 165B3 CYP165B3 0.0005
4960 Putative cytochrome P450-family protein SCO7417 0.0005
4926 Heme-based aerotactic transducer hemAT hemAT 0.0005
4972 P450cin cinA 0.0005
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0005
4993 Hydroxylamine oxidoreductase hao1 0.0005
4952 Catalase/peroxidase katA 0.0005
3093 Catalase HPII katE 0.0005
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0005
6221 Steroid hormone receptor ERR1 ESRRA 0.0005
6527 Lymphocyte antigen 96 LY96 0.0005
6755 Poliovirus receptor PVR 0.0005
751 Potassium channel subfamily K member 6 KCNK6 0.0004
1039 Histone deacetylase 9 HDAC9 0.0004
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0004
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0004
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0004
6020 Aldehyde oxidase AOX1 0.0004
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0004
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0004
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0004
6750 ADP-ribosylation factor 6 ARF6 0.0004
4373 Medium-chain-fatty-acid--CoA ligase Not Available 0.0004
6524 Protein tonB tonB 0.0004
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0004
172 Potassium channel subfamily K member 1 KCNK1 0.0004
936 Ephrin type-A receptor 2 EPHA2 0.0004
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0004
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0004
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0004
6163 Copper-transporting ATPase 2 ATP7B 0.0004
6165 Copper-transporting ATPase 1 ATP7A 0.0004
165 FL cytokine receptor FLT3 0.0004
2616 Ganglioside GM2 activator GM2A 0.0004
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0004
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0004
291 Nitric-oxide synthase, endothelial NOS3 0.0004
2435 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0004
6613 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpxC 0.0004
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0004
3957 Adenosine deaminase ADA 0.0004
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0004
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0004
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0004
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0004
908 Glutathione S-transferase theta-1 GSTT1 0.0004
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0004
469 Annexin A1 ANXA1 0.0004
2297 Genome polyprotein Not Available 0.0004
2322 Genome polyprotein Not Available 0.0004
2694 Genome polyprotein Not Available 0.0004
2719 Genome polyprotein Not Available 0.0004
2860 Genome polyprotein Not Available 0.0004
2928 Genome polyprotein Not Available 0.0004
3160 Genome polyprotein Not Available 0.0004
3260 Genome polyprotein Not Available 0.0004
4783 Genome polyprotein Not Available 0.0004
5726 Genome polyprotein Not Available 0.0004
5779 Genome polyprotein Not Available 0.0004
5867 Genome polyprotein Not Available 0.0004
6253 Genome polyprotein Not Available 0.0004
6301 Genome polyprotein Not Available 0.0004
6380 Genome polyprotein Not Available 0.0004
6381 Genome polyprotein Not Available 0.0004
6437 Genome polyprotein Not Available 0.0004
6520 Genome polyprotein Not Available 0.0004
6521 Genome polyprotein Not Available 0.0004
6652 Genome polyprotein Not Available 0.0004
6734 Genome polyprotein Not Available 0.0004
6735 Genome polyprotein Not Available 0.0004
6736 Genome polyprotein Not Available 0.0004
6737 Genome polyprotein Not Available 0.0004
6738 Genome polyprotein Not Available 0.0004
6739 Genome polyprotein Not Available 0.0004
6744 Genome polyprotein Not Available 0.0004
6748 Genome polyprotein Not Available 0.0004
6894 Genome polyprotein Not Available 0.0004
6898 Genome polyprotein Not Available 0.0004
284 DNA-directed RNA polymerase beta chain rpoB 0.0004
5773 DNA-directed RNA polymerase beta chain rpoB 0.0004
6316 ADP-ribosylation factor 1 ARF1 0.0004
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0003
4920 Peroxidase/catalase katG 0.0003
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0003
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0003
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0003
2119 Cytochrome b5 CYB5A 0.0003
864 Gag-Pol polyprotein gag-pol 0.0003
2237 Gag-Pol polyprotein gag-pol 0.0003
2326 Gag-Pol polyprotein gag-pol 0.0003
2451 Gag-Pol polyprotein gag-pol 0.0003
2901 Gag-Pol polyprotein gag-pol 0.0003
3165 Gag-Pol polyprotein gag-pol 0.0003
3722 Gag-Pol polyprotein gag-pol 0.0003
6306 Gag-Pol polyprotein gag-pol 0.0003
6624 Gag-Pol polyprotein gag-pol 0.0003
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0003
4990 PpcA ppcA 0.0003
4988 Sulfite oxidase, mitochondrial SUOX 0.0003
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0003
3375 Acidic cytochrome c3 Not Available 0.0003
4037 Hypothetical protein GPX1 0.0003
4297 Hypothetical protein SP_1951 0.0003
4521 Hypothetical protein BC_2969 0.0003
4540 Hypothetical protein TM_1070 0.0003
4555 Hypothetical protein MT1739 0.0003
4569 Hypothetical protein mshD 0.0003
4578 Hypothetical protein PA3270 0.0003
4747 Hypothetical protein PA3967 0.0003
5177 Hypothetical protein TM_0096 0.0003
5194 Hypothetical protein PA1204 0.0003
5240 Hypothetical protein Rv2991 0.0003
5370 Hypothetical protein TM_1158 0.0003
5710 Hypothetical protein Tb927.5.1360 0.0003
3570 Cytochrome P450 152A1 cypC 0.0003
2915 Sensor protein fixL fixL 0.0003
4944 Sensor protein fixL fixL 0.0003
4289 Cytochrome P450 TT_P0059 0.0003
6262 Cytochrome P450 staP 0.0003
4992 Cytochrome c peroxidase Not Available 0.0003
4813 Heme oxygenase hmuO 0.0003
5769 Heme oxygenase Not Available 0.0003
4385 Cytochrome c' Not Available 0.0003
4967 Cytochrome c' cycA 0.0003
5038 Cytochrome c' Not Available 0.0003
5223 Cytochrome c' cycP 0.0003
896 Glutathione S-transferase Mu 1 GSTM1 0.0003
2230 Catalase CAT 0.0003
3249 Catalase katA 0.0003
3625 Catalase katA 0.0003
4539 Catalase katA 0.0003
4941 Catalase katB 0.0003
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0003
3670 Soluble cytochrome b562 precursor cybC 0.0003
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0003
3411 Cytochrome P450 121 cyp121 0.0003
3291 Cytochrome c-552 cycA 0.0003
4927 Cytochrome c-552 nrfA 0.0003
4938 Cytochrome c-552 cycA 0.0003
4953 Cytochrome c-552 nrfA 0.0003
5217 Cytochrome c-552 cycM 0.0003
2617 Nitric oxide synthase oxygenase nos 0.0003
2701 Nitric oxide synthase oxygenase nos 0.0003
3102 Flavohemoprotein hmp 0.0003
4969 Flavohemoprotein hmp 0.0003
2427 Ferrichrome-iron receptor fhuA 0.0003
6228 Nuclear receptor coactivator 1 NCOA1 0.0003
6264 cAMP-dependent protein kinase inhibitor alpha PKIA 0.0003
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0003
605 Fumarate reductase flavoprotein subunit frdA 0.0003
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0003
3673 Fumarate reductase flavoprotein subunit fccA 0.0003
4912 Fumarate reductase flavoprotein subunit ifcA 0.0003
6549 Fumarate reductase flavoprotein subunit frdA 0.0003
2972 6-deoxyerythronolide B hydroxylase eryF 0.0003
952 Dipeptidyl peptidase 4 DPP4 0.0003
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0003
4608 Putative cytochrome P450 SCO1207 0.0003
4963 Putative cytochrome P450 SCO2884 0.0003
6254 Putative cytochrome P450 SCO6998 0.0003
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0003
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0002
358 Cystathionine beta-synthase CBS 0.0002
693 Hemoglobin subunit beta HBB 0.0002
6268 Hydroxyacid oxidase 1 HAO1 0.0002
810 Heme oxygenase 1 HMOX1 0.0002
3391 Heme oxygenase 1 pbsA1 0.0002
2298 Cytochrome P450-cam camC 0.0002
76 Nitric-oxide synthase, brain NOS1 0.0002
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