DT-Web

DB02039 - S-Acetyl-Cysteine


Identification
Name S-Acetyl-Cysteine
Accession Number DB02039 (EXPT02873)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 163.195
Groups experimental
Monoisotopic Weight 163.030313849
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Histone acetyltransferase KAT5
Name Histone acetyltransferase KAT5
Gene Name KAT5
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Acetyl-CoA acetyltransferase
Name Acetyl-CoA acetyltransferase
Gene Name phbA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.4683
3-oxoacyl-[acyl-carrier-protein] synthase 3
Name 3-oxoacyl-[acyl-carrier-protein] synthase 3
Gene Name fabH
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0414
3-hydroxy-3-methylglutaryl CoA synthase
Name 3-hydroxy-3-methylglutaryl CoA synthase
Gene Name mvaS
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.7671

Predictions


Id Partner name Gene Name Score
3138 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 1.0414
4568 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 1.0414
6370 3-oxoacyl-[acyl-carrier-protein] synthase 3 fabH 1.0414
4601 HMG-CoA synthase mvaS 0.1432
4574 PROBABLE NAPHTHOATE SYNTHASE MENB menB 0.143
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.1281
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.1262
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.1262
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.1081
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.1044
888 3-oxoacyl-[acyl-carrier-protein] synthase 2 fabF 0.0691
889 3-oxoacyl-[acyl-carrier-protein] synthase 1 fabB 0.0618
6860 3-oxoacyl-[acyl-carrier-protein] synthase 1 kasA 0.0618
1295 Fatty acid synthase FASN 0.0563
2409 Acetyl-CoA acetyltransferase, cytosolic ACAT2 0.0502
5898 Complement C3 C3 0.0351
6677 Myelin P2 protein PMP2 0.0306
2517 Subtilisin BPN' apr 0.0292
5366 Sugar-phosphate isomerase TM_1080 0.0253
2688 Peptide deformylase def 0.0253
2708 Peptide deformylase def 0.0253
3004 Peptide deformylase def 0.0253
4337 Peptide deformylase def 0.0253
4338 Peptide deformylase def 0.0253
5368 Peptide deformylase def 0.0253
5371 Peptide deformylase def 0.0253
6375 Peptide deformylase def 0.0253
6378 Peptide deformylase def 0.0253
6379 Peptide deformylase def 0.0253
6776 Peptide deformylase def 0.0253
6900 Peptide deformylase def 0.0253
5365 Metallo beta-lactamase blaVIM-2 0.0252
5369 Golgi-associated plant pathogenesis-related protein 1 GLIPR2 0.0252
4699 Methylaspartate ammonia-lyase Not Available 0.0252
5367 Peroxiredoxin prx 0.0252
2443 Azurin azu 0.0246
4031 Glutathione S-transferase A1 GSTA1 0.0227
3596 Deoxynucleotide monophosphate kinase 1 0.022
3858 Cathepsin L CTSL1 0.022
3105 M-phase inducer phosphatase 2 CDC25B 0.0202
2664 S-ribosylhomocysteine lyase luxS 0.0192
2725 S-ribosylhomocysteine lyase luxS 0.0192
904 Glutathione S-transferase P GSTP1 0.0182
2385 Penicillin acylase Not Available 0.0181
4564 YvbK protein yvbK 0.0172
4576 Aac(6')-Ii protein aac(6')-Ii 0.0171
4567 Putative acyl-CoA thioester hydrolase HI0827 HI_0827 0.0171
2528 Fatty acid metabolism regulator protein fadR 0.0171
6740 Fatty acid metabolism regulator protein fadR 0.0171
4579 Serine acetyltransferase cysE 0.0171
6807 Serine acetyltransferase cysE 0.0171
4566 Acyl-CoA hydrolase BC_2038 0.0171
4572 Acyl-CoA hydrolase BH0798 0.0171
4577 4'-phosphopantetheinyl transferase sfp sfp 0.0171
4037 Hypothetical protein GPX1 0.0171
4297 Hypothetical protein SP_1951 0.0171
4521 Hypothetical protein BC_2969 0.0171
4540 Hypothetical protein TM_1070 0.0171
4555 Hypothetical protein MT1739 0.0171
4569 Hypothetical protein mshD 0.0171
4578 Hypothetical protein PA3270 0.0171
4747 Hypothetical protein PA3967 0.0171
5177 Hypothetical protein TM_0096 0.0171
5194 Hypothetical protein PA1204 0.0171
5240 Hypothetical protein Rv2991 0.0171
5370 Hypothetical protein TM_1158 0.0171
5710 Hypothetical protein Tb927.5.1360 0.0171
3560 Gentamicin 3'-acetyltransferase aacC1 0.0149
4565 Aminoglycoside 6'-N-acetyltransferase aac(6')-Iy 0.0149
3489 Acetyl-coenzyme A synthetase acs 0.0149
2396 Formyl-coenzyme A transferase frc 0.0149
3457 Formyl-coenzyme A transferase frc 0.0149
3317 Holo-[acyl-carrier-protein] synthase acpS 0.0149
4381 Holo-[acyl-carrier-protein] synthase acpS 0.0149
4563 Acetyl transferase rimL 0.0149
3125 Protease synthase and sporulation negative regulatory protein PAI 1 paiA 0.0149
3024 Crotonobetainyl-CoA:carnitine CoA-transferase caiB 0.0149
3729 Citrate synthase gltA 0.0149
4575 Citrate synthase cit 0.0149
4580 Citrate synthase gltA 0.0149
3199 Phosphopantetheine adenylyltransferase coaD 0.0138
3543 Phosphopantetheine adenylyltransferase coaD 0.0138
3567 Phosphopantetheine adenylyltransferase coaD 0.0138
5289 Phosphopantetheine adenylyltransferase coaD 0.0138
2285 Streptogramin A acetyltransferase vatD 0.0138
2560 Galactoside O-acetyltransferase lacA 0.0138
2377 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Not Available 0.0138
3178 Formate acetyltransferase 1 pflB 0.0137
3697 Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase glmU 0.0137
4573 Histone acetyltransferase PCAF KAT2B 0.0137
2248 Malate synthase G glcB 0.0137
3190 Malate synthase G glcB 0.0137
2371 Pantothenate kinase coaA 0.0131
4404 FcbC1 protein fcbC 0.013
2376 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase dapD 0.0124
551 Carnitine O-acetyltransferase CRAT 0.0122
687 Tyrosine-protein phosphatase non-receptor type 1 PTPN1 0.0113
4388 Aminoglycoside 2'-N-acetyltransferase aac 0.0106
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