Identification
Name Cyclic Adenosine Monophosphate
Accession Number DB02527 (EXPT00959)
Type small molecule
Description Cyclic adenosine monophosphate (cAMP, cyclic AMP or 3'-5'-cyclic adenosine monophosphate) is a molecule that is important in many biological processes; it is derived from adenosine triphosphate (ATP).
Structure
Categories (*)
Molecular Weight 329.2059
Groups experimental
Monoisotopic Weight 329.052519653
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions Not Available
Food Interactions Not Available
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Name Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Gene Name HCN2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
cAMP-dependent protein kinase type I-alpha regulatory subunit
Name cAMP-dependent protein kinase type I-alpha regulatory subunit
Gene Name PRKAR1A
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.3614
cAMP-dependent protein kinase type II-beta regulatory subunit
Name cAMP-dependent protein kinase type II-beta regulatory subunit
Gene Name PRKAR2B
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score Not Available
Adenylate cyclase
Name Adenylate cyclase
Gene Name cyaB2
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.5968
Mll3241 protein
Name Mll3241 protein
Gene Name mll3241
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 0.5288
Catabolite gene activator
Name Catabolite gene activator
Gene Name crp
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.597
Multidrug resistance-associated protein 4
Name Multidrug resistance-associated protein 4
Gene Name ABCC4
Actions substrate,inhibitor
References
  • Chen ZS, Lee K, Kruh GD: Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine. J Biol Chem. 2001 Sep 7;276(36):33747-54. Epub 2001 Jul 10. - Pubmed
  • van Aubel RA, Smeets PH, Peters JG, Bindels RJ, Russel FG: The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP. J Am Soc Nephrol. 2002 Mar;13(3):595-603. - Pubmed
  • Chen ZS, Lee K, Walther S, Raftogianis RB, Kuwano M, Zeng H, Kruh GD: Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system. Cancer Res. 2002 Jun 1;62(11):3144-50. - Pubmed
  • Lai L, Tan TM: Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues. Biochem J. 2002 Feb 1;361(Pt 3):497-503. - Pubmed
DTHybrid score 0.4456
Multidrug resistance-associated protein 5
Name Multidrug resistance-associated protein 5
Gene Name ABCC5
Actions inhibitor
References
  • Jedlitschky G, Burchell B, Keppler D: The multidrug resistance protein 5 functions as an ATP-dependent export pump for cyclic nucleotides. J Biol Chem. 2000 Sep 29;275(39):30069-74. - Pubmed
DTHybrid score 0.3784
ATP-binding cassette transporter sub-family C member 11
Name ATP-binding cassette transporter sub-family C member 11
Gene Name ABCC11
Actions substrate,inhibitor
References
  • Chen ZS, Guo Y, Belinsky MG, Kotova E, Kruh GD: Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11). Mol Pharmacol. 2005 Feb;67(2):545-57. Epub 2004 Nov 10. - Pubmed
  • Guo Y, Kotova E, Chen ZS, Lee K, Hopper-Borge E, Belinsky MG, Kruh GD: MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine. J Biol Chem. 2003 Aug 8;278(32):29509-14. Epub 2003 May 22. - Pubmed
DTHybrid score 0.3805
Solute carrier family 22 member 6
Name Solute carrier family 22 member 6
Gene Name SLC22A6
Actions substrate
References
  • Sekine T, Watanabe N, Hosoyamada M, Kanai Y, Endou H: Expression cloning and characterization of a novel multispecific organic anion transporter. J Biol Chem. 1997 Jul 25;272(30):18526-9. - Pubmed
DTHybrid score 0.6272
Solute carrier family 22 member 8
Name Solute carrier family 22 member 8
Gene Name SLC22A8
Actions substrate
References
  • Cha SH, Sekine T, Fukushima JI, Kanai Y, Kobayashi Y, Goya T, Endou H: Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Mol Pharmacol. 2001 May;59(5):1277-86. - Pubmed
DTHybrid score 0.5112
Solute carrier family 22 member 7
Name Solute carrier family 22 member 7
Gene Name SLC22A7
Actions substrate
References
  • Sun W, Wu RR, van Poelje PD, Erion MD: Isolation of a family of organic anion transporters from human liver and kidney. Biochem Biophys Res Commun. 2001 May 4;283(2):417-22. - Pubmed
DTHybrid score 0.4096
Id Partner name Gene Name Score
4655 Adenylate cyclase cyaC 0.5968
3806 cGMP-dependent 3',5'-cyclic phosphodiesterase PDE2A 0.1962
1024 Solute carrier family 22 member 11 SLC22A11 0.1877
587 Serum albumin ALB 0.0993
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0977
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0954
1588 Multidrug resistance protein 1 ABCB1 0.0953
4757 Cytochrome P450 2C9 CYP2C9 0.0932
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.091
4512 Cytochrome P450 3A4 CYP3A4 0.0864
862 Multidrug resistance-associated protein 1 ABCC1 0.0776
290 Prostaglandin G/H synthase 2 PTGS2 0.0713
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.069
4924 Cytochrome P450 2C8 CYP2C8 0.0686
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0674
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0668
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0644
20 Prostaglandin G/H synthase 1 PTGS1 0.0635
6016 Cytochrome P450 2C19 CYP2C19 0.058
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0555
6141 Sodium/bile acid cotransporter SLC10A1 0.0546
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0542
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0525
4200 Cytochrome P450 1A2 CYP1A2 0.0504
6145 Solute carrier family 22 member 1 SLC22A1 0.0488
738 Monocarboxylate transporter 1 SLC16A1 0.0485
6144 Solute carrier family 22 member 2 SLC22A2 0.0485
118 Organic cation/carnitine transporter 2 SLC22A5 0.0484
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0397
4118 Cytochrome P450 3A5 CYP3A5 0.0387
5626 Nucleoside diphosphate kinase B NME2 0.0385
293 Gamma-glutamyl hydrolase GGH 0.0382
3917 Methylenetetrahydrofolate reductase MTHFR 0.0373
6020 Aldehyde oxidase AOX1 0.0366
6148 Multidrug resistance-associated protein 7 ABCC10 0.036
87 Hypoxanthine-guanine phosphoribosyltransferase HPRT1 0.0354
6149 Solute carrier family 22 member 10 SLC22A10 0.0353
776 Bile salt export pump ABCB11 0.0351
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0346
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0343
6137 Multidrug resistance-associated protein 6 ABCC6 0.0342
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.034
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0335
1650 Heme carrier protein 1 SLC46A1 0.0334
6167 Organic solute transporter subunit beta OSTB 0.0324
6107 Cytochrome P450 3A7 CYP3A7 0.0324
6166 Organic solute transporter subunit alpha OSTA 0.0324
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.031
5294 Nucleoside diphosphate kinase A NME1 0.0308
342 P protein [Includes: DNA-directed DNA polymerase P 0.0303
612 P protein [Includes: DNA-directed DNA polymerase P 0.0303
3947 Xanthine dehydrogenase/oxidase XDH 0.03
6013 Cytochrome P450 2E1 CYP2E1 0.0291
718 Folate receptor gamma FOLR3 0.0291
299 Folate receptor beta FOLR2 0.0291
804 Mitochondrial folate transporter/carrier SLC25A32 0.029
338 DNA polymerase UL30 0.0285
379 DNA polymerase UL54 0.0285
697 DNA polymerase ORF28 0.0285
2482 DNA polymerase 43 0.0285
4104 DNA polymerase BALF5 0.0285
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0279
22 30S ribosomal protein S4 rpsD 0.0278
6714 30S ribosomal protein S4 rpsD 0.0278
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0275
24 Thymidylate synthase TMP1 0.0274
359 Thymidylate synthase TYMS 0.0274
2626 Thymidylate synthase thyA 0.0274
2729 Thymidylate synthase thyA 0.0274
5352 Thymidylate synthase THYA 0.0274
4119 Cytochrome P450 2D6 CYP2D6 0.0268
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0268
6147 Solute carrier family 22 member 3 SLC22A3 0.0264
140 30S ribosomal protein S9 rpsI 0.0262
6719 30S ribosomal protein S9 rpsI 0.0262
6725 30S ribosomal protein S9 rpsI 0.0262
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0259
645 Penicillin-binding protein 1A mrcA 0.0238
5805 Penicillin-binding protein 1A ponA 0.0238
6185 Penicillin-binding protein 1A mrcA 0.0238
6799 Penicillin-binding protein 1A pbpA 0.0238
1405 Thiopurine S-methyltransferase TPMT 0.0233
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0227
6030 Cytochrome P450 2B6 CYP2B6 0.0225
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0223
633 Penicillin-binding proteins 1A/1B pbpA 0.0219
543 Penicillin-binding protein 1B mrcB 0.0216
6186 Penicillin-binding protein 1B ponB 0.0216
6822 Penicillin-binding protein 1b pbp1b 0.0216
6844 Penicillin-binding protein 1b pbp1b 0.0216
5718 Cytochrome P450 2A6 CYP2A6 0.0209
833 Organic cation/carnitine transporter 1 SLC22A4 0.0207
6689 TraN protein traN 0.0205
6670 Ig kappa chain V-I region Bi Not Available 0.0204
6671 Ig heavy chain V-III region VH26 Not Available 0.0204
4905 Cytochrome c2 Not Available 0.0204
4939 Cytochrome c2 cycA 0.0204
4964 Cytochrome c2 cycA 0.0204
4979 Cytochrome c2 cycA 0.0204
6673 Cytochrome c2 cycA 0.0204
6681 Probable N-acetylneuraminic acid outer membrane channel protein nanC nanC 0.0204
6672 Destrin DSTN 0.0204
6680 Cofilin-1 CFL1 0.0204
6685 Outer membrane protein II porB 0.0204
6668 Cytochrome c oxidase subunit 1-beta ctaDII 0.0204
6688 TraF protein traF 0.0204
6690 BenF-like porin PFL_1329 0.0204
6676 Fe(3+)-pyochelin receptor fptA 0.0204
6687 TraO protein traO 0.0204
6404 Rhomboid protease glpG glpG 0.0204
6797 Rhomboid protease glpG glpG 0.0204
6674 Nuclear factor erythroid 2-related factor 1 NFE2L1 0.0204
3710 Acyl-CoA thioesterase 2 tesB 0.0204
6679 Colicin-Ia cia 0.0204
6218 Pannexin-1 PANX1 0.0204
3639 Thymidine phosphorylase deoA 0.0198
3936 Thymidine phosphorylase TYMP 0.0198
2016 Dipeptidase 1 DPEP1 0.0197
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0195
4604 Liver carboxylesterase 1 CES1 0.0195
6024 Cytochrome P450 1A1 CYP1A1 0.0194
5353 Glutamate decarboxylase alpha gadA 0.0178
2320 Thymidine kinase, cytosolic TK1 0.0178
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0178
6474 Outer membrane protein W ompW 0.0178
6438 Outer membrane protein G ompG 0.0178
3578 Protein crcA crcA 0.0178
2447 Ammonia channel amtB 0.0177
2925 Long-chain fatty acid transport protein fadL 0.0177
6385 H subunit of photosynthetic reaction center complex puhA 0.0177
3395 Iron(III) dicitrate transport protein fecA fecA 0.0177
6480 Outer membrane usher protein papC papC 0.0177
6675 Colicin-E3 ceaC 0.0177
6678 Colicin I receptor cirA 0.0177
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0176
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.0176
4217 Telomerase reverse transcriptase TERT 0.0171
6171 Solute carrier family 28 member 3 SLC28A3 0.0166
3957 Adenosine deaminase ADA 0.0164
6428 Light-harvesting protein B-800/850 beta chain Not Available 0.0164
6427 Light-harvesting protein B-800/850 alpha chain Not Available 0.0164
6533 Light-harvesting protein B-800/850 alpha chain A1 0.0164
6524 Protein tonB tonB 0.0164
2679 Vitamin B12 transporter btuB btuB 0.0164
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0158
3587 Gastrotropin FABP6 0.0156
6677 Myelin P2 protein PMP2 0.0155
6033 High affinity interleukin-8 receptor A CXCR1 0.015
2261 Major NAD(P)H-flavin oxidoreductase Not Available 0.0149
6043 Putative G-protein coupled receptor 44 GPR44 0.0149
6085 Fatty acid-binding protein, intestinal FABP2 0.0149
5818 Folate receptor alpha FOLR1 0.0148
6012 Tryptophan 2,3-dioxygenase TDO2 0.0145
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0141
592 Carbonic anhydrase 4 CA4 0.0141
6042 Prostaglandin reductase 2 PTGR2 0.0141
404 DNA gyrase subunit A gyrA 0.0139
6224 DNA gyrase subunit A gyrA 0.0139
4226 Uridine phosphorylase 2 UPP2 0.0137
1867 Major prion protein PRNP 0.0136
3688 Branched-chain-amino-acid aminotransferase ilvE 0.0136
1313 Lactoylglutathione lyase GLO1 0.0135
6351 Photosynthetic reaction center cytochrome c subunit pufC 0.0135
6353 Reaction center protein L chain pufL 0.0135
6454 Reaction center protein L chain pufL 0.0135
6683 Reaction center protein L chain pufL 0.0135
6354 Reaction center protein M chain pufM 0.0134
6455 Reaction center protein M chain pufM 0.0134
6684 Reaction center protein M chain pufM 0.0134
6352 Reaction center protein H chain puhA 0.0134
6456 Reaction center protein H chain puhA 0.0134
6682 Reaction center protein H chain puhA 0.0134
115 Penicillin-binding protein 2 mrdA 0.0134
6069 Penicillin-binding protein 2 mrdA 0.0134
6118 Penicillin-binding protein 2 penA 0.0134
6187 Penicillin-binding protein 2 pbpA 0.0134
6686 Penicillin-binding protein 2 pbp2 0.0134
6939 Penicillin-binding protein 2 mrdA 0.0134
7163 Penicillin-binding protein 2 pbpA 0.0134
295 Carbonic anhydrase 1 CA1 0.0133
357 Carbonic anhydrase 2 CA2 0.0131
489 Monocarboxylate transporter 2 SLC16A7 0.013
1141 Sialidase-1 NEU1 0.0129
64 Neuraminidase NA 0.0129
641 Neuraminidase NA 0.0129
2676 Neuraminidase NA 0.0129
3026 Neuraminidase NA 0.0129
3519 Neuraminidase NA 0.0129
6007 Neuraminidase NA 0.0129
558 Solute carrier family 12 member 1 SLC12A1 0.0128
2981 Phospholipase A2, membrane associated PLA2G2A 0.0127
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0127
2828 Squalene--hopene cyclase shc 0.0126
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0124
1 Peptidoglycan synthetase ftsI ftsI 0.0124
4155 Peptidoglycan synthetase ftsI ftsI 0.0124
308 30S ribosomal protein S12 rpsL 0.0122
6704 30S ribosomal protein S12 rpsL 0.0122
438 Taste receptor type 1 member 2 TAS1R2 0.0122
4225 Uridine phosphorylase 1 UPP1 0.0121
4094 Gamma-aminobutyric acid type B receptor, subunit 2 GABBR2 0.0119
33 Cystine/glutamate transporter SLC7A11 0.0119
6207 30S ribosomal protein S14 rpsN 0.0117
6209 30S ribosomal protein S19 rpsS 0.0117
6712 30S ribosomal protein S19 rpsS 0.0117
6726 30S ribosomal protein S19 rpsS 0.0117
6031 Cytochrome P450 3A43 CYP3A43 0.0117
413 Amidophosphoribosyltransferase PPAT 0.0117
2515 Amidophosphoribosyltransferase purF 0.0117
3714 Amidophosphoribosyltransferase purF 0.0117
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0115
2207 Rhodopsin RHO 0.0113
3686 Acyl-CoA thioesterase I precursor tesA 0.0111
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.011
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.011
2249 Aspartate aminotransferase aspC 0.011
2671 Aspartate aminotransferase aspC 0.011
5490 Aspartate aminotransferase Not Available 0.011
4790 Glycosyltransferase GtfA gtfA 0.011
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0109
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0109
3811 Cytochrome P450 19A1 CYP19A1 0.0109
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0107
124 Histamine H2 receptor HRH2 0.0106
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0106
275 Arachidonate 5-lipoxygenase ALOX5 0.0105
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0104
244 Angiotensin-converting enzyme ACE 0.0103
5482 Sialidase-2 NEU2 0.0101
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.01
527 Prostacyclin receptor PTGIR 0.01
887 DNA gyrase subunit B gyrB 0.0099
4150 DNA gyrase subunit B gyrB 0.0099
6225 DNA gyrase subunit B gyrB 0.0099
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0098
672 Prostaglandin F2-alpha receptor PTGFR 0.0098
1198 Serum paraoxonase/arylesterase 1 PON1 0.0097
6223 Penicillin-binding protein 1C pbpC 0.0097
1558 Transient receptor potential cation channel subfamily V member 1 TRPV1 0.0095
240 Gamma-aminobutyric acid type B receptor, subunit 1 GABBR1 0.0093
867 Penicillin-binding protein 3 pbpC 0.0092
6119 Penicillin-binding protein 3 pbp3 0.0092
7154 Penicillin-binding protein 3 pbp3 0.0092
7157 Penicillin-binding protein 3 LMHCC_2184 0.0092
7162 Penicillin-binding protein 3 pbpB 0.0092
7172 Penicillin-binding protein 3 pbp3 0.0092
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0091
1654 Interleukin-1 beta IL1B 0.0091
1244 Low-density lipoprotein receptor-related protein 2 LRP2 0.009
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0089
6106 Cytochrome P450 2C18 CYP2C18 0.0089
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0087
4122 Histone deacetylase 2 HDAC2 0.0087
4773 Deoxycytidine kinase DCK 0.0087
889 3-oxoacyl-[acyl-carrier-protein] synthase 1 fabB 0.0084
6860 3-oxoacyl-[acyl-carrier-protein] synthase 1 kasA 0.0084
53 Solute carrier family 12 member 5 SLC12A5 0.0084
663 Solute carrier family 12 member 4 SLC12A4 0.0084
3810 Catechol O-methyltransferase COMT 0.0084
373 Transthyretin TTR 0.0084
723 Cytosolic phospholipase A2 PLA2G4A 0.0083
1757 Myeloperoxidase MPO 0.0083
6126 Carbonic anhydrase 7 CA7 0.0082
65 Matrix metalloproteinase-9 Not Available 0.0081
136 Estrogen receptor ESR1 0.008
16 Adenosine A1 receptor ADORA1 0.008
3939 Amine oxidase [flavin-containing] B MAOB 0.0079
332 Beta-lactamase blaZ 0.0079
2478 Beta-lactamase ampC 0.0079
2613 Beta-lactamase ampC 0.0079
2635 Beta-lactamase ampC 0.0079
2700 Beta-lactamase penP 0.0079
5445 Beta-lactamase blaB 0.0079
6019 Beta-lactamase SHV-7 0.0079
6701 Beta-lactamase cphA 0.0079
1178 Adenosine A2a receptor ADORA2A 0.0078
310 Solute carrier family 12 member 2 SLC12A2 0.0078
365 Dihydrofolate reductase DHFR 0.0076
2381 Dihydrofolate reductase DFR1 0.0076
2833 Dihydrofolate reductase Not Available 0.0076
2931 Dihydrofolate reductase folA 0.0076
3544 Dihydrofolate reductase folA 0.0076
3682 Dihydrofolate reductase folA 0.0076
6642 Dihydrofolate reductase folA 0.0076
6756 Dihydrofolate reductase dfrA 0.0076
468 Cytochrome P450 4A11 CYP4A11 0.0076
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0074
494 Caspase-1 CASP1 0.0073
183 Vascular endothelial growth factor A VEGFA 0.0072
1648 Elastin ELN 0.0072
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0071
1507 Cytochrome c CYCS 0.007
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0069
1898 Cytochrome P450 1B1 CYP1B1 0.0069
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0069
952 Dipeptidyl peptidase 4 DPP4 0.0066
3760 Penicillin-binding protein 5 precursor dacA 0.0066
908 Glutathione S-transferase theta-1 GSTT1 0.0066
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0065
477 DNA topoisomerase 4 subunit A parC 0.0064
886 DNA topoisomerase 4 subunit A parC 0.0064
6226 DNA topoisomerase 4 subunit A parC 0.0064
273 Apoptosis regulator Bcl-2 BCL2 0.0064
6184 D-alanyl-D-alanine carboxypeptidase dacC dacC 0.0062
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0062
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0061
2077 Caspase-3 CASP3 0.0061
130 Prostacyclin synthase PTGIS 0.0061
3932 Glutathione S-transferase A2 GSTA2 0.006
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.006
509 Thymidine kinase TK 0.006
570 Thymidine kinase TK 0.006
2559 Thymidine kinase TK 0.006
3430 Thymidine kinase tdk 0.006
3518 Thymidine kinase TK 0.006
5301 Thymidine kinase tdk 0.006
5771 Thymidine kinase ORF36 0.006
7009 Thymidine kinase ORF36 0.006
6220 Aryl hydrocarbon receptor AHR 0.006
146 Androgen receptor AR 0.006
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0059
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0059
819 Penicillin-binding protein 4 dacB 0.0059
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0058
896 Glutathione S-transferase Mu 1 GSTM1 0.0058
471 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 0.0057
756 Sex hormone-binding globulin SHBG 0.0056
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0055
466 Solute carrier family 12 member 3 SLC12A3 0.0055
284 DNA-directed RNA polymerase beta chain rpoB 0.0054
5773 DNA-directed RNA polymerase beta chain rpoB 0.0054
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.0054
5756 D-alanyl-D-alanine carboxypeptidase dac 0.0054
2021 Thrombomodulin THBD 0.0053
818 50S ribosomal protein L10 rplJ 0.0053
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0053
4238 50S ribosomal protein L4 rplD 0.0052
5578 50S ribosomal protein L4 rplD 0.0052
6173 50S ribosomal protein L4 rplD 0.0052
6219 50S ribosomal protein L4 rplD 0.0052
3426 Glutamine synthetase glnA 0.0051
3987 Glutamine synthetase GLUL 0.0051
904 Glutathione S-transferase P GSTP1 0.0051
253 Sodium/potassium-transporting ATPase gamma chain FXYD2 0.0051
26 Vascular endothelial growth factor receptor 3 FLT4 0.0051
165 FL cytokine receptor FLT3 0.005
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0049
277 Purine nucleoside phosphorylase PNP 0.0049
2870 Purine nucleoside phosphorylase punA 0.0049
2945 Purine nucleoside phosphorylase punA 0.0049
4659 Purine nucleoside phosphorylase TM_1596 0.0049
4825 Purine nucleoside phosphorylase TTHA1435 0.0049
32 Vascular endothelial growth factor receptor 1 FLT1 0.0048
4237 50S ribosomal protein L22 rplV 0.0047
2391 Ferrochelatase hemH 0.0047
6502 Ferrochelatase DKFZp686P18130 0.0047
1591 Ferrochelatase, mitochondrial FECH 0.0047
228 Beta platelet-derived growth factor receptor PDGFRB 0.0046
1039 Histone deacetylase 9 HDAC9 0.0045
6014 Cytochrome P450 2A13 CYP2A13 0.0045
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0045
6339 Ig kappa chain V-II region RPMI 6410 Not Available 0.0044
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.0044
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0044
817 DNA topoisomerase 2-alpha TOP2A 0.0043
5698 Riboflavin synthase alpha chain ribE 0.0043
504 Mast/stem cell growth factor receptor KIT 0.0042
6165 Copper-transporting ATPase 1 ATP7A 0.0041
6163 Copper-transporting ATPase 2 ATP7B 0.0041
408 Riboflavin kinase RFK 0.0041
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.0041
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.0041
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.0041
6493 Cytochrome c oxidase subunit 6C COX6C 0.0041
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.0041
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.0041
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.0041
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.0041
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.0041
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.0041
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0041
6559 Cytochrome c oxidase subunit 2 ctaC 0.0041
6669 Cytochrome c oxidase subunit 2 ctaC 0.0041
371 Cytochrome c oxidase subunit 1 MT-CO1 0.0041
6558 Cytochrome c oxidase subunit 1 ctaD 0.0041
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.004
4034 Glutaredoxin-1 GLRX 0.004
4043 Glutaredoxin-2, mitochondrial GLRX2 0.004
4037 Hypothetical protein GPX1 0.004
4297 Hypothetical protein SP_1951 0.004
4521 Hypothetical protein BC_2969 0.004
4540 Hypothetical protein TM_1070 0.004
4555 Hypothetical protein MT1739 0.004
4569 Hypothetical protein mshD 0.004
4578 Hypothetical protein PA3270 0.004
4747 Hypothetical protein PA3967 0.004
5177 Hypothetical protein TM_0096 0.004
5194 Hypothetical protein PA1204 0.004
5240 Hypothetical protein Rv2991 0.004
5370 Hypothetical protein TM_1158 0.004
5710 Hypothetical protein Tb927.5.1360 0.004
1928 Leukotriene C4 synthase LTC4S 0.004
4029 Microsomal glutathione S-transferase 3 MGST3 0.004
4032 Microsomal glutathione S-transferase 1 MGST1 0.004
4030 Thioredoxin domain-containing protein 12 TXNDC12 0.004
4035 Glutathione S-transferase Mu 5 GSTM5 0.004
4039 CDNA FLJ23636 fis, clone CAS07176 GPX8 0.004
4040 Glutathione peroxidase 7 GPX7 0.004
910 Epididymal secretory glutathione peroxidase GPX5 0.004
4036 Glutathione peroxidase 6 GPX6 0.004
903 Glutathione S-transferase A5 GSTA5 0.004
911 Glutathione peroxidase 3 GPX3 0.004
906 Glutathione peroxidase 1 GPX1 0.004
900 Glutathione S-transferase A4 GSTA4 0.004
4038 Glutathione peroxidase 4 GPX4 0.004
1975 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial GPX4 0.004
4042 Glutathione transferase omega-2 GSTO2 0.004
907 Glutathione peroxidase 2 GPX2 0.004
4033 S-formylglutathione hydrolase ESD 0.004
1056 Gamma-glutamyltranspeptidase 1 GGT1 0.004
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.004
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0039
3941 Amine oxidase [flavin-containing] A MAOA 0.0039
6146 High affinity copper uptake protein 1 SLC31A1 0.0039
702 UMP-CMP kinase CMPK1 0.0039
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0039
407 Vascular endothelial growth factor receptor 2 KDR 0.0039
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0038
2540 Choloylglycine hydrolase cbh 0.0037
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0037
2472 Voltage-gated potassium channel kcsA 0.0037
6366 Voltage-gated potassium channel kcsA 0.0037
1792 Tissue-type plasminogen activator PLAT 0.0037
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0037
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0036
3319 Hydroxyacylglutathione hydrolase HAGH 0.0036
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0035
897 Glutathione S-transferase kappa 1 GSTK1 0.0035
6131 Carbonic anhydrase 14 CA14 0.0035
492 Histamine H1 receptor HRH1 0.0035
898 Glutathione S-transferase A3 GSTA3 0.0035
6501 Fatty acid-binding protein, liver FABP1 0.0035
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0035
909 Maleylacetoacetate isomerase GSTZ1 0.0035
899 Glutathione S-transferase Mu 3 GSTM3 0.0034
905 Glutathione transferase omega-1 GSTO1 0.0034
594 Thyroxine-binding globulin SERPINA7 0.0034
4041 Microsomal glutathione S-transferase 2 MGST2 0.0034
6122 Carbonic anhydrase 3 CA3 0.0033
3007 Carbonic anhydrase 12 CA12 0.0033
4205 Carbonic anhydrase 9 CA9 0.0033
5924 Microtubule-associated protein 4 MAP4 0.0032
5923 Microtubule-associated protein tau MAPT 0.0032
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0032
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0032
3809 Estrogen-related receptor gamma ESRRG 0.0031
758 Thyroid hormone receptor alpha THRA 0.0031
2165 Glutathione S-transferase Mu 2 GSTM2 0.0031
207 Glutathione synthetase GSS 0.0031
5269 Glutathione synthetase gshB 0.0031
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0031
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0031
950 Alpha platelet-derived growth factor receptor PDGFRA 0.003
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.003
1852 Microtubule-associated protein 2 MAP2 0.003
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.003
6500 Phospholipase A2 PLA2G1B 0.0029
654 Flavin reductase BLVRB 0.0029
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0029
268 Adenosine A2b receptor ADORA2B 0.0029
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0029
901 Glutathione S-transferase Mu 4 GSTM4 0.0029
4252 Penicillin-binding protein 5 dacA 0.0028
159 Penicillin-binding protein 2B penA 0.0028
6121 Penicillin-binding protein 2B penA 0.0028
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0028
346 Thyroid hormone receptor beta-1 THRB 0.0028
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0028
5126 Arginase rocF 0.0027
1025 Aquaporin-1 AQP1 0.0027
4031 Glutathione S-transferase A1 GSTA1 0.0026
517 Alcohol dehydrogenase 1C ADH1C 0.0026
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0026
29 Tubulin beta-1 chain TUBB1 0.0025
714 Glutathione reductase, mitochondrial GSR 0.0025
740 Argininosuccinate synthase ASS1 0.0025
865 Argininosuccinate synthase ASS1 0.0025
2680 Argininosuccinate synthase argG 0.0025
3194 Argininosuccinate synthase argG 0.0025
707 72 kDa type IV collagenase MMP2 0.0025
109 Mitochondrial carnitine/acylcarnitine carrier protein CACL SLC25A29 0.0025
636 Mitochondrial carnitine/acylcarnitine carrier protein SLC25A20 0.0025
3923 Cholinesterase BCHE 0.0023
624 Guanidinoacetate N-methyltransferase GAMT 0.0022
3014 Ribonuclease UK114 HRSP12 0.0022
3718 Hydrogen peroxide-inducible genes activator oxyR 0.0022
3617 Non-heme chloroperoxidase cpo 0.0022
5426 Non-heme chloroperoxidase cpo 0.0022
5428 Replication protein repA 0.0022
5427 Hydroxyquinol 1,2-dioxygenase chqB 0.0022
3018 HTH-type transcriptional regulator malT malT 0.0022
3830 Calreticulin CALR 0.0022
1196 Complement decay-accelerating factor CD55 0.0021
6168 Solute carrier family 22 member 16 SLC22A16 0.0021
6151 Monocarboxylate transporter 10 SLC16A10 0.0021
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0021
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0021
551 Carnitine O-acetyltransferase CRAT 0.0021
412 Peroxisomal carnitine O-octanoyltransferase CROT 0.0021
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.002
6034 Hydroxyindole O-methyltransferase ASMT 0.002
6035 Nuclear receptor ROR-beta RORB 0.002
6036 Eosinophil peroxidase EPX 0.002
1714 Mitogen-activated protein kinase 3 MAPK3 0.0019
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0019
2958 Probable tautomerase ydcE pptA 0.0019
2573 Cocaine esterase cocE 0.0019
7263 Cocaine esterase Not Available 0.0019
2808 Chloramphenicol acetyltransferase 3 cat3 0.0019
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0019
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.0019
3115 Ras-related protein Rab-9 RAB9A 0.0019
3603 Chlorocatechol 1,2-dioxygenase clcA 0.0018
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0018
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0018
765 Indoleamine 2,3-dioxygenase IDO1 0.0017
2417 Chloramphenicol acetyltransferase cat 0.0017
3278 Chloramphenicol acetyltransferase cat 0.0017
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0017
2810 Dr hemagglutinin structural subunit draA 0.0017
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0017
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0017
380 Cytochrome P450 17A1 CYP17A1 0.0017
1119 Peroxiredoxin-5, mitochondrial PRDX5 0.0016
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0016
571 Melatonin receptor type 1A MTNR1A 0.0016
362 Melatonin receptor type 1B MTNR1B 0.0016
5682 Ribonuclease pancreatic RNASE1 0.0016
2300 Lysozyme E 0.0016
3633 Lysozyme R 0.0016
5597 Lysozyme 17 0.0016
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0016
459 Retinoic acid receptor RXR-alpha RXRA 0.0016
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0015
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0015
2693 Heat-labile enterotoxin B chain eltB 0.0014
199 Monocarboxylate transporter 8 SLC16A2 0.0014
4674 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase cumD 0.0014
6645 D-amino-acid oxidase DAO 0.0014
822 Aldose reductase AKR1B1 0.0014
4010 Mitochondrial dicarboxylate carrier SLC25A10 0.0013
1410 Oxidoreductase HSD17B6 0.0013
4725 Oxidoreductase Not Available 0.0013
5124 Oxidoreductase Not Available 0.0013
4007 Succinate receptor 1 SUCNR1 0.0013
4008 Succinyl-CoA:3-ketoacid-coenzyme A transferase 2, mitochondrial OXCT2 0.0013
4002 Succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial SUCLG1 0.0013
673 Solute carrier family 13 member 3 SLC13A3 0.0013
391 Succinyl-CoA ligase [GDP-forming] beta-chain, mitochondrial SUCLG2 0.0013
4009 Succinyl-CoA ligase [ADP-forming] beta-chain, mitochondrial SUCLA2 0.0013
498 Solute carrier family 13 member 2 SLC13A2 0.0013
25 Solute carrier family 13 member 1 SLC13A1 0.0013
751 Potassium channel subfamily K member 6 KCNK6 0.0013
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0012
4003 Succinyl-CoA:3-ketoacid-coenzyme A transferase 1, mitochondrial OXCT1 0.0012
172 Potassium channel subfamily K member 1 KCNK1 0.0012
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0011
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0011
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0011
4000 Prolyl 4-hydroxylase subunit alpha-2 P4HA2 0.0011
585 Aspartyl/asparaginyl beta-hydroxylase ASPH 0.0011
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0011
3940 Gamma-butyrobetaine dioxygenase BBOX1 0.0011
97 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 PLOD1 0.0011
3938 Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 PLOD3 0.0011
3964 Trimethyllysine dioxygenase, mitochondrial TMLHE 0.0011
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0011
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0011
4006 Succinate dehydrogenase cytochrome b560 subunit, mitochondrial SDHC 0.0011
4001 Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial SDHB 0.0011
465 Calmodulin CALM1 0.0011
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0011
1192 Sulfotransferase 1A1 SULT1A1 0.001
70 Type-1 angiotensin II receptor AGTR1 0.001
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.001
997 Protein kinase C beta type PRKCB 0.001
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.001
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.001
3949 Prolyl 3-hydroxylase 2 LEPREL1 0.001
3945 Prolyl 3-hydroxylase 1 LEPRE1 0.001
3951 Prolyl 3-hydroxylase 3 LEPREL2 0.001
3999 Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial SDHD 0.001
1275 Estrogen sulfotransferase SULT1E1 0.001
197 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial SDHA 0.001
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.001
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.001
634 Squalene monooxygenase SQLE 0.001
7196 Squalene monooxygenase ERG1 0.001
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.001
1970 Protein kinase C alpha type PRKCA 0.001
1050 Bile salt sulfotransferase SULT2A1 0.001
6102 Arylamine N-acetyltransferase 2 NAT2 0.0009
2408 Tyrosine-protein kinase SYK SYK 0.0009
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0009
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0009
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0009
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0009
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0008
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0008
2236 Casein kinase II subunit alpha CSNK2A1 0.0007
824 Sodium-dependent serotonin transporter SLC6A4 0.0007
869 Estrogen receptor beta ESR2 0.0006
6263 cAMP-dependent protein kinase catalytic subunit alpha PRKACA 0.0006