DT-Web

Major NAD(P)H-flavin oxidoreductase


Partner ID 2261
Name Major NAD(P)H-flavin oxidoreductase
Synonyms 3989
Gene name Not Available
General function Energy production and conversion
Specific function Involved in bioluminescence. It is a good supplier of reduced flavin mononucleotide (FMNH2) to the bioluminescence reaction. Major FMN reductase. It is capable of using both NADH and NADPH as electron donors. As electron acceptor, FMN is the most effective, FAD is considerably effective, and riboflavin is the least effective
Gene sequence + ...

ATGACGCATCCAATTATTCATGATCTTGAAAATCGTTATACATCAAAAAAATATGACCCATCAAAGAAAGTATCTCAAGAAGATTTAGCGGTTTTGCTTGAGGCTCTGCGTTTATCTGCTTCTTCAATTAATTCACAGCCTTGGAAATTCATTGTTATTGAATCCGATGCAGCGAAGCAACGTATGCATGATTCGTTTGCAAATATGCATCAGTTTAATCAACCTCACATCAAAGCGTGTTCTCATGTGATTTTATTTGCAAATAAGCTTTCGTATACACGAGATGATTATGATGTGGTTTTATCTAAAGCGGTTGCTGACAAGCGTATTACTGAAGAGCAAAAAGAAGCTGCTTTTGCTTCGTTTAAGTTTGTAGAATTGAACTGTGATGAAAATGGTGAGCATAAAGCATGGACTAAGCCTCAAGCTTATTTAGCTCTTGGTAATGCTCTGCATACATTAGCTAGACTGAACATTGACTCAACAACAATGGAAGGCATTGATCCTGAATTATTGAGTGAAATTTTTGCTGATGAATTAAAAGGGTATGAATGTCATGTTGCTTTAGCCATTGGTTATCATCATCCAAGCGAAGATTATAATGCCTCTTTGCCTAAGTCTCGTAAGGCATTTGAAGACGTAATTACCATCCTTTAG
Protein sequence + ...

MTHPIIHDLENRYTSKKYDPSKKVSQEDLAVLLEALRLSASSINSQPWKFIVIESDAAKQRMHDSFANMHQFNQPHIKACSHVILFANKLSYTRDDYDVVLSKAVADKRITEEQKEAAFASFKFVELNCDENGEHKAWTKPQAYLALGNALHTLARLNIDSTTMEGIDPELLSEIFADELKGYECHVALAIGYHHPSEDYNASLPKSRKAFEDVITIL
GO Classification
function
catalytic activity
oxidoreductase activity
process
physiological process
metabolism
cellular metabolism
generation of precursor metabolites and energy
electron transport
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Drugs


Associated as Target

Id Name
DB01650 trans-2-hydroxycinnamic acid
DB03247 Riboflavin Monophosphate
DB03410 4-hydroxycoumarin

Associated as Prediction

Id Name
DB00114 Pyridoxal Phosphate
DB00139 Succinic acid
DB00140 Riboflavin
DB00155 L-Citrulline
DB00157 NADH
DB00166 Lipoic Acid
DB00168 Aspartame
DB00175 Pravastatin
DB00181 Baclofen
DB00198 Oseltamivir
DB00254 Doxycycline
DB00279 Liothyronine
DB00286 Conjugated Estrogens
DB00300 Tenofovir
DB00305 Mitomycin
DB00313 Valproic Acid
DB00328 Indomethacin
DB00345 Aminohippurate
DB00390 Digoxin
DB00437 Allopurinol
DB00456 Cefalotin
DB00469 Tenoxicam
DB00493 Cefotaxime
DB00495 Zidovudine
DB00501 Cimetidine
DB00536 Guanidine
DB00544 Fluorouracil
DB00554 Piroxicam
DB00563 Methotrexate
DB00567 Cephalexin
DB00577 Valaciclovir
DB00583 L-Carnitine
DB00584 Enalapril
DB00586 Diclofenac
DB00595 Oxytetracycline
DB00624 Testosterone
DB00665 Nilutamide
DB00694 Daunorubicin
DB00695 Furosemide
DB00698 Nitrofurantoin
DB00718 Adefovir Dipivoxil
DB00759 Tetracycline
DB00783 Estradiol
DB00787 Acyclovir
DB00812 Phenylbutazone
DB00863 Ranitidine
DB00865 Benzphetamine
DB00887 Bumetanide
DB00908 Quinidine
DB00917 Dinoprostone
DB00927 Famotidine
DB00936 Salicyclic acid
DB00997 Doxorubicin
DB01004 Ganciclovir
DB01009 Ketoprofen
DB01017 Minocycline
DB01032 Probenecid
DB01033 Mercaptopurine
DB01050 Ibuprofen
DB01051 Novobiocin
DB01053 Penicillin G
DB01065 Melatonin
DB01092 Ouabain
DB01097 Leflunomide
DB01101 Capecitabine
DB01117 Atovaquone
DB01140 Cefadroxil
DB01160 Dinoprost Tromethamine
DB01212 Ceftriaxone
DB01326 Cefamandole
DB01327 Cefazolin
DB01329 Cefoperazone
DB01414 Cefacetrile
DB01466 Ethylmorphine
DB01583 Liotrix
DB01597 Cilastatin
DB01650 trans-2-hydroxycinnamic acid
DB01676 Trinitrotoluene
DB01821 L-N(Omega)-Nitroarginine-2,4-L-Diaminobutyric Amide
DB01907 Nicotinamide-Adenine-Dinucleotide
DB01942 Formic Acid
DB01997 3-Bromo-7-Nitroindazole
DB02027 N-{(4s)-4-Amino-5-[(2-Aminoethyl)Amino]Pentyl}-N'-Nitroguanidine
DB02044 N-(3-(Aminomethyl)Benzyl)Acetamidine
DB02060 Cyclohexanone
DB02073 Biliverdine Ix Alpha
DB02077 L-N(Omega)-Nitroarginine-(4r)-Amino-L-Proline Amide
DB02143 N-Isopropyl-N'-Hydroxyguanidine
DB02164 N-Sulfo-Flavin Mononucleotide
DB02209 Pyridoxine-5'-Phosphate
DB02262 Orotic Acid
DB02279 Benzoylformic Acid
DB02303 (5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione
DB02338 Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate
DB02379 Beta-D-Glucose
DB02508 Isopentyl Pyrophosphate
DB02527 Cyclic Adenosine Monophosphate
DB02613 Decylamine-N,N-Dimethyl-N-Oxide
DB02644 N-Omega-Propyl-L-Arginine
DB02659 Cholic Acid
DB02692 (6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin
DB02727 N-Butyl-N'-Hydroxyguanidine
DB02926 2-Oxo-Glutaric Acid
DB02944 Alpha-D-Mannose
DB02991 S-Ethyl-N-[4-(Trifluoromethyl)Phenyl]Isothiourea
DB03014 Heme
DB03048 6-Carboxymethyluracil
DB03064 3-Decyl-2,5-Dioxo-4-Hydroxy-3-Pyrroline
DB03144 N-Omega-Hydroxy-L-Arginine
DB03147 Flavin-Adenine Dinucleotide
DB03228 5-[Bis-2(Chloro-Ethyl)-Amino]-2,4-Dintro-Benzamide
DB03247 Riboflavin Monophosphate
DB03345 Beta-Mercaptoethanol
DB03350 Cobalt Hexammine Ion
DB03410 4-hydroxycoumarin
DB03419 Uracil
DB03431 Adenosine-5'-Diphosphate
DB03449 N-(4-(2-((3-Chlorophenylmethyl)Amino)Ethyl)Phenyl)-2-Thiophecarboxamidine
DB03461 2'-Monophosphoadenosine 5'-Diphosphoribose
DB03480 Brequinar Analog
DB03523 6-Fluoro-2-(2'-Fluoro-1,1'-Biphenyl-4-Yl)-3-Methylquinoline-4-Carboxylic Acid
DB03553 Glutaric Acid
DB03554 5-Iodouracil
DB03651 2,4,6-Trinitrophenol
DB03698 5-Mercaptoethanol-2-Decenoyl-Coenzyme A
DB03707 S-Ethyl-N-Phenyl-Isothiourea
DB03710 N5-(1-Imino-3-Butenyl)-L-Ornithine
DB03738 Pantothenoylaminoethenethiol
DB03793 Benzoic Acid
DB03805 Antiproliferative Agent A771726
DB03814 2-(N-Morpholino)-Ethanesulfonic Acid
DB03884 3-Phenylpyruvic Acid
DB03892 5-N-Allyl-Arginine
DB03902 Oxalic Acid
DB04133 Degraded Cephaloridine
DB04138 2,4-Dinitro,5-[Bis(2-Bromoethyl)Amino]-N-(2',3'-Dioxopropyl)Benzamide
DB04147 Lauryl Dimethylamine-N-Oxide
DB04223 Nitroarginine
DB04253 CB1954
DB04272 Citric Acid
DB04281 2-[4-(4-Chlorophenyl)Cyclohexylidene]-3,4-Dihydroxy-1(2h)-Naphthalenone
DB04345 7,8-dimethylalloxazine
DB04348 Taurocholic Acid
DB04363 Mesobiliverdin Iv Alpha
DB04374 4-Carboxy-5-(1-Pentyl)Hexylsulfanyl-1,2,3-Triazole
DB04392 Bishydroxy[2h-1-Benzopyran-2-One,1,2-Benzopyrone]
DB04519 Caprylic acid
DB04528 2,4-Dinitrophenol
DB04583 5-(AMINOCARBONYL)-1,1':4',1''-TERPHENYL-3-CARBOXYLICACID
DB06335 Saxagliptin
DB06710 Methyltestosterone
DB06979 5-(dodecylthio)-1H-1,2,3-triazole-4-carboxylic acid
DB07060 3-(INDOL-3-YL) LACTATE
DB07373 ANDROSTA-1,4-DIENE-3,17-DIONE
DB07443 (2Z)-N-biphenyl-4-yl-2-cyano-3-hydroxybut-2-enamide
DB07559 (2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide
DB07561 (2Z)-2-cyano-N-(3'-ethoxybiphenyl-4-yl)-3-hydroxybut-2-enamide
DB07646 UNDECYLAMINE-N,N-DIMETHYL-N-OXIDE
DB07837 [4-(5-naphthalen-2-yl-1H-pyrrolo[2,3-b]pyridin-3-yl)phenyl]acetic acid
DB07907 (2S)-2-HYDROXYOCTANOIC ACID
DB07975 2-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENT-1-ENE-1-CARBOXYLIC ACID
DB07976 3-{[(3-FLUORO-3'-METHOXYBIPHENYL-4-YL)AMINO]CARBONYL}THIOPHENE-2-CARBOXYLIC ACID
DB07977 3-({[3,5-DIFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)THIOPHENE-2-CARBOXYLIC ACID
DB07978 2-({[2,3,5,6-TETRAFLUORO-3'-(TRIFLUOROMETHOXY)BIPHENYL-4-YL]AMINO}CARBONYL)CYCLOPENTA-1,3-DIENE-1-CARBOXYLIC ACID
DB08006 N-anthracen-2-yl-5-methyl[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
DB08008 5-methyl-N-[4-(trifluoromethyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine
DB08018 N-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE
DB08019 N-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine
DB08169 (2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide
DB08172 (2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide
DB08191 4-(5-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)benzoic acid
DB08249 3,6,9,12,15-PENTAOXATRICOSAN-1-OL
DB08837 Tetraethylammonium
DB08880 Teriflunomide
DB08912 Dabrafenib
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