DT-Web

DB04630 - Aldosterone


Identification
Name Aldosterone
Accession Number DB04630
Type small molecule
Description A hormone secreted by the adrenal cortex that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 360.444
Groups experimental
Monoisotopic Weight 360.193674006
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Mineralocorticoid receptor
Name Mineralocorticoid receptor
Gene Name NR3C2
Pharmacological action unknown
Actions Not Available
References
  • Bruner KL, Derfoul A, Robertson NM, Guerriero G, Fernandes-Alnemri T, Alnemri ES, Litwack G: The unliganded mineralocorticoid receptor is associated with heat shock proteins 70 and 90 and the immunophilin FKBP-52. Recept Signal Transduct. 1997;7(2):85-98. - Pubmed
  • Bunda S, Liu P, Wang Y, Liu K, Hinek A: Aldosterone induces elastin production in cardiac fibroblasts through activation of insulin-like growth factor-I receptors in a mineralocorticoid receptor-independent manner. Am J Pathol. 2007 Sep;171(3):809-19. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.5087

Enzymes


Cytochrome P450 11B1, mitochondrial
Name Cytochrome P450 11B1, mitochondrial
Gene Name CYP11B1
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3622
Cytochrome P450 11B2, mitochondrial
Name Cytochrome P450 11B2, mitochondrial
Gene Name CYP11B2
Actions substrate
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3765
Cytochrome P450 17A1
Name Cytochrome P450 17A1
Gene Name CYP17A1
Actions inducer
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.2509

Transporters


Multidrug resistance protein 1
Name Multidrug resistance protein 1
Gene Name ABCB1
Actions substrate,inducer
References
  • Romiti N, Tramonti G, Chieli E: Influence of different chemicals on MDR-1 P-glycoprotein expression and activity in the HK-2 proximal tubular cell line. Toxicol Appl Pharmacol. 2002 Sep 1;183(2):83-91. - Pubmed
  • Ueda K, Okamura N, Hirai M, Tanigawara Y, Saeki T, Kioka N, Komano T, Hori R: Human P-glycoprotein transports cortisol, aldosterone, and dexamethasone, but not progesterone. J Biol Chem. 1992 Dec 5;267(34):24248-52. - Pubmed
DTHybrid score 0.3583
Organic cation/carnitine transporter 2
Name Organic cation/carnitine transporter 2
Gene Name SLC22A5
Actions inhibitor
References
  • Ohashi R, Tamai I, Yabuuchi H, Nezu JI, Oku A, Sai Y, Shimane M, Tsuji A: Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance. J Pharmacol Exp Ther. 1999 Nov;291(2):778-84. - Pubmed
DTHybrid score 0.2411
Solute carrier organic anion transporter family member 1A2
Name Solute carrier organic anion transporter family member 1A2
Gene Name SLCO1A2
Actions inhibitor
References
  • Kanai N, Lu R, Bao Y, Wolkoff AW, Schuster VL: Transient expression of oatp organic anion transporter in mammalian cells: identification of candidate substrates. Am J Physiol. 1996 Feb;270(2 Pt 2):F319-25. - Pubmed
  • Bossuyt X, Muller M, Hagenbuch B, Meier PJ: Polyspecific drug and steroid clearance by an organic anion transporter of mammalian liver. J Pharmacol Exp Ther. 1996 Mar;276(3):891-6. - Pubmed
DTHybrid score 0.26

Predictions


Id Partner name Gene Name Score
4512 Cytochrome P450 3A4 CYP3A4 0.2141
4119 Cytochrome P450 2D6 CYP2D6 0.1418
4118 Cytochrome P450 3A5 CYP3A5 0.1416
6107 Cytochrome P450 3A7 CYP3A7 0.1377
4924 Cytochrome P450 2C8 CYP2C8 0.1188
146 Androgen receptor AR 0.0933
4757 Cytochrome P450 2C9 CYP2C9 0.0886
6016 Cytochrome P450 2C19 CYP2C19 0.0842
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0824
4200 Cytochrome P450 1A2 CYP1A2 0.0817
871 Glucocorticoid receptor NR3C1 0.0814
756 Sex hormone-binding globulin SHBG 0.0707
3811 Cytochrome P450 19A1 CYP19A1 0.0656
6145 Solute carrier family 22 member 1 SLC22A1 0.0644
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0638
5718 Cytochrome P450 2A6 CYP2A6 0.0624
862 Multidrug resistance-associated protein 1 ABCC1 0.0622
94 5-hydroxytryptamine 4 receptor HTR4 0.0604
587 Serum albumin ALB 0.0599
1729 Solute carrier family 22 member 6 SLC22A6 0.058
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0557
833 Organic cation/carnitine transporter 1 SLC22A4 0.0538
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.053
776 Bile salt export pump ABCB11 0.0523
6142 Solute carrier family 22 member 8 SLC22A8 0.0521
6013 Cytochrome P450 2E1 CYP2E1 0.0516
6144 Solute carrier family 22 member 2 SLC22A2 0.0502
1680 Solute carrier family 2, facilitated glucose transporter member 1 SLC2A1 0.0497
614 Progesterone receptor PGR 0.0495
6024 Cytochrome P450 1A1 CYP1A1 0.0483
6030 Cytochrome P450 2B6 CYP2B6 0.0481
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0476
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.046
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0454
831 D(2) dopamine receptor DRD2 0.0447
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0435
6141 Sodium/bile acid cotransporter SLC10A1 0.0414
629 Alpha-2B adrenergic receptor ADRA2B 0.0395
469 Annexin A1 ANXA1 0.0387
6147 Solute carrier family 22 member 3 SLC22A3 0.0386
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0382
232 Corticosteroid-binding globulin SERPINA6 0.0373
269 Adrenodoxin, mitochondrial FDX1 0.0358
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0332
6228 Nuclear receptor coactivator 1 NCOA1 0.0319
2298 Cytochrome P450-cam camC 0.0318
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0306
6143 Solute carrier family 22 member 7 SLC22A7 0.0299
1024 Solute carrier family 22 member 11 SLC22A11 0.0294
6106 Cytochrome P450 2C18 CYP2C18 0.0286
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0284
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0282
3923 Cholinesterase BCHE 0.0281
260 Cytochrome P450 51 ERG11 0.028
761 Cytochrome P450 51 ERG11 0.028
3163 Cytochrome P450 51 cyp51 0.028
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.028
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.0278
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0275
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0275
1898 Cytochrome P450 1B1 CYP1B1 0.0271
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0267
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0267
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0256
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0248
136 Estrogen receptor ESR1 0.0245
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0242
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0242
290 Prostaglandin G/H synthase 2 PTGS2 0.0241
1050 Bile salt sulfotransferase SULT2A1 0.0217
477 DNA topoisomerase 4 subunit A parC 0.0213
886 DNA topoisomerase 4 subunit A parC 0.0213
6226 DNA topoisomerase 4 subunit A parC 0.0213
404 DNA gyrase subunit A gyrA 0.021
6224 DNA gyrase subunit A gyrA 0.021
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0204
817 DNA topoisomerase 2-alpha TOP2A 0.0196
492 Histamine H1 receptor HRH1 0.0193
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0192
2164 Multidrug resistance-associated protein 4 ABCC4 0.0184
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0179
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0178
33 Cystine/glutamate transporter SLC7A11 0.0173
244 Angiotensin-converting enzyme ACE 0.0171
738 Monocarboxylate transporter 1 SLC16A1 0.0167
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0159
159 Penicillin-binding protein 2B penA 0.0153
6121 Penicillin-binding protein 2B penA 0.0153
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0151
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0148
723 Cytosolic phospholipase A2 PLA2G4A 0.0147
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0144
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0144
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0141
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.014
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0139
556 Alpha-1A adrenergic receptor ADRA1A 0.0139
904 Glutathione S-transferase P GSTP1 0.013
6137 Multidrug resistance-associated protein 6 ABCC6 0.0129
193 Beta-1 adrenergic receptor ADRB1 0.0129
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0127
824 Sodium-dependent serotonin transporter SLC6A4 0.0126
3587 Gastrotropin FABP6 0.0123
20 Prostaglandin G/H synthase 1 PTGS1 0.012
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.0118
731 HIV-1 protease HIV-1 protease 0.0117
6220 Aryl hydrocarbon receptor AHR 0.0116
468 Cytochrome P450 4A11 CYP4A11 0.0115
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0115
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0112
124 Histamine H2 receptor HRH2 0.011
766 Beta-2 adrenergic receptor ADRB2 0.0106
869 Estrogen receptor beta ESR2 0.0106
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0105
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0105
7 Nitric oxide synthase, inducible NOS2 0.0105
633 Penicillin-binding proteins 1A/1B pbpA 0.0104
318 Alpha-2A adrenergic receptor ADRA2A 0.0104
474 Acetylcholinesterase ACHE 0.0102
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0102
3941 Amine oxidase [flavin-containing] A MAOA 0.0102
115 Penicillin-binding protein 2 mrdA 0.0099
6069 Penicillin-binding protein 2 mrdA 0.0099
6118 Penicillin-binding protein 2 penA 0.0099
6187 Penicillin-binding protein 2 pbpA 0.0099
6686 Penicillin-binding protein 2 pbp2 0.0099
6939 Penicillin-binding protein 2 mrdA 0.0099
7163 Penicillin-binding protein 2 pbpA 0.0099
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0096
6031 Cytochrome P450 3A43 CYP3A43 0.0095
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0093
84 Nuclear receptor 0B1 NR0B1 0.0091
6148 Multidrug resistance-associated protein 7 ABCC10 0.009
465 Calmodulin CALM1 0.0089
6010 Thiamine transporter 1 SLC19A2 0.0089
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0086
632 Alpha-1B adrenergic receptor ADRA1B 0.0086
4604 Liver carboxylesterase 1 CES1 0.0086
6048 Troponin C, skeletal muscle TNNC2 0.0084
1 Peptidoglycan synthetase ftsI ftsI 0.0083
4155 Peptidoglycan synthetase ftsI ftsI 0.0083
713 Sodium-dependent dopamine transporter SLC6A3 0.0082
789 Alpha-1D adrenergic receptor ADRA1D 0.0081
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0081
175 Thiamin pyrophosphokinase 1 TPK1 0.008
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0079
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0079
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0078
1010 Cytochrome P450 51A1 CYP51A1 0.0078
624 Guanidinoacetate N-methyltransferase GAMT 0.0078
594 Thyroxine-binding globulin SERPINA7 0.0077
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0077
867 Penicillin-binding protein 3 pbpC 0.0077
6119 Penicillin-binding protein 3 pbp3 0.0077
7154 Penicillin-binding protein 3 pbp3 0.0077
7157 Penicillin-binding protein 3 LMHCC_2184 0.0077
7162 Penicillin-binding protein 3 pbpB 0.0077
7172 Penicillin-binding protein 3 pbp3 0.0077
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0076
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0076
6136 Multidrug resistance-associated protein 5 ABCC5 0.0076
6167 Organic solute transporter subunit beta OSTB 0.0073
1636 Trace amine-associated receptor 1 TAAR1 0.0073
6166 Organic solute transporter subunit alpha OSTA 0.0073
645 Penicillin-binding protein 1A mrcA 0.0073
5805 Penicillin-binding protein 1A ponA 0.0073
6185 Penicillin-binding protein 1A mrcA 0.0073
6799 Penicillin-binding protein 1A pbpA 0.0073
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0072
502 5-hydroxytryptamine 2A receptor HTR2A 0.0072
758 Thyroid hormone receptor alpha THRA 0.0072
320 5-hydroxytryptamine 1A receptor HTR1A 0.0071
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0071
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0071
378 Alpha-2C adrenergic receptor ADRA2C 0.007
844 Epidermal growth factor receptor EGFR 0.007
131 Synaptic vesicular amine transporter SLC18A2 0.0069
3939 Amine oxidase [flavin-containing] B MAOB 0.0069
5934 Cytochrome P450 26A1 CYP26A1 0.0069
1517 Beta-3 adrenergic receptor ADRB3 0.0068
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0067
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0067
847 Mu-type opioid receptor OPRM1 0.0066
4238 50S ribosomal protein L4 rplD 0.0064
5578 50S ribosomal protein L4 rplD 0.0064
6173 50S ribosomal protein L4 rplD 0.0064
6219 50S ribosomal protein L4 rplD 0.0064
1757 Myeloperoxidase MPO 0.0064
346 Thyroid hormone receptor beta-1 THRB 0.0064
192 Creatine kinase, ubiquitous mitochondrial CKMT1A 0.0063
456 Creatine kinase, sarcomeric mitochondrial CKMT2 0.0063
92 Creatine kinase B-type CKB 0.0063
414 Sodium- and chloride-dependent creatine transporter 1 SLC6A8 0.0063
3432 Multidrug-efflux transporter 1 regulator bmrR 0.0063
4476 Mannitol dehydrogenase mtlD 0.0063
467 Delta-type opioid receptor OPRD1 0.0062
725 5-hydroxytryptamine 1D receptor HTR1D 0.0062
885 5-hydroxytryptamine 1B receptor HTR1B 0.0061
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0061
373 Transthyretin TTR 0.0061
982 Cocaine- and amphetamine-regulated transcript protein CARTPT 0.006
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.006
332 Beta-lactamase blaZ 0.0059
2478 Beta-lactamase ampC 0.0059
2613 Beta-lactamase ampC 0.0059
2635 Beta-lactamase ampC 0.0059
2700 Beta-lactamase penP 0.0059
5445 Beta-lactamase blaB 0.0059
6019 Beta-lactamase SHV-7 0.0059
6701 Beta-lactamase cphA 0.0059
4237 50S ribosomal protein L22 rplV 0.0059
23 D(1A) dopamine receptor DRD1 0.0059
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0059
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0059
696 Kappa-type opioid receptor OPRK1 0.0059
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0058
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0058
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0058
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0058
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0058
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0058
6067 Penicillin binding protein 2a mecA 0.0058
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0057
788 Creatine kinase M-type CKM 0.0057
976 Platelet glycoprotein IX GP9 0.0055
1192 Sulfotransferase 1A1 SULT1A1 0.0055
6149 Solute carrier family 22 member 10 SLC22A10 0.0054
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0053
6182 Cytochrome P450 2J2 CYP2J2 0.0052
860 Nicotinamide N-methyltransferase NNMT 0.0051
583 Nicotinate-nucleotide pyrophosphorylase [carboxylating] QPRT 0.0051
2442 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0051
2459 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0051
699 Nicotinic acid receptor 1 GPR109A 0.0051
928 Nicotinic acid receptor 2 GPR109B 0.0051
341 5-hydroxytryptamine 3 receptor HTR3A 0.0051
6151 Monocarboxylate transporter 10 SLC16A10 0.005
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.005
1353 DNA topoisomerase 1 TOP1 0.005
3552 DNA topoisomerase 1 topA 0.005
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0049
511 5-hydroxytryptamine 1F receptor HTR1F 0.0048
558 Solute carrier family 12 member 1 SLC12A1 0.0048
291 Nitric-oxide synthase, endothelial NOS3 0.0048
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0047
2616 Ganglioside GM2 activator GM2A 0.0047
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0046
2472 Voltage-gated potassium channel kcsA 0.0046
6366 Voltage-gated potassium channel kcsA 0.0046
952 Dipeptidyl peptidase 4 DPP4 0.0046
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0045
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0045
199 Monocarboxylate transporter 8 SLC16A2 0.0044
3947 Xanthine dehydrogenase/oxidase XDH 0.0044
4120 NADPH--cytochrome P450 reductase POR 0.0043
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0043
638 D(3) dopamine receptor DRD3 0.0043
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0043
1291 cAMP response element-binding protein CREB1 0.0041
6085 Fatty acid-binding protein, intestinal FABP2 0.0041
4210 Toll-like receptor 4 TLR4 0.0041
436 5-hydroxytryptamine 2B receptor HTR2B 0.004
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.004
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.004
161 Tubulin beta chain TUBB 0.0039
312 Tubulin beta chain TUB2 0.0039
828 Phenylalanine-4-hydroxylase PAH 0.0039
3109 Phenylalanine-4-hydroxylase phhA 0.0039
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0039
1064 DNA (cytosine-5)-methyltransferase 1 DNMT1 0.0037
6218 Pannexin-1 PANX1 0.0037
504 Mast/stem cell growth factor receptor KIT 0.0036
122 P2Y purinoceptor 12 P2RY12 0.0036
4203 Histamine N-methyltransferase HNMT 0.0036
751 Potassium channel subfamily K member 6 KCNK6 0.0036
5126 Arginase rocF 0.0036
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0035
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0035
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0035
2449 Tubulin alpha-3 chain TUBA1A 0.0035
164 Histamine H4 receptor HRH4 0.0035
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0034
6033 High affinity interleukin-8 receptor A CXCR1 0.0034
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0034
1341 Histamine H3 receptor HRH3 0.0034
172 Potassium channel subfamily K member 1 KCNK1 0.0033
499 Arginine decarboxylase ADC 0.0033
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0032
109 Mitochondrial carnitine/acylcarnitine carrier protein CACL SLC25A29 0.0032
636 Mitochondrial carnitine/acylcarnitine carrier protein SLC25A20 0.0032
500 Monocarboxylate transporter 4 SLC16A3 0.0032
3810 Catechol O-methyltransferase COMT 0.0032
2300 Lysozyme E 0.0032
3633 Lysozyme R 0.0032
5597 Lysozyme 17 0.0032
2499 Tubulin beta-2C chain TUBB2C 0.0031
6168 Solute carrier family 22 member 16 SLC22A16 0.0031
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0031
1630 Integrin beta-2 ITGB2 0.0031
577 Argininosuccinate lyase ASL 0.0031
834 Arginase-2, mitochondrial ARG2 0.0031
238 Peroxisome proliferator-activated receptor gamma PPARG 0.003
740 Argininosuccinate synthase ASS1 0.003
865 Argininosuccinate synthase ASS1 0.003
2680 Argininosuccinate synthase argG 0.003
3194 Argininosuccinate synthase argG 0.003
590 5-hydroxytryptamine 2C receptor HTR2C 0.003
150 Cationic amino acid transporter 3 SLC7A3 0.003
235 High-affinity cationic amino acid transporter 1 SLC7A1 0.003
58 Cationic amino acid transporter 4 SLC7A4 0.003
26 Vascular endothelial growth factor receptor 3 FLT4 0.0029
683 Potassium transporter GK0582 0.0029
70 Type-1 angiotensin II receptor AGTR1 0.0029
663 Solute carrier family 12 member 4 SLC12A4 0.0029
53 Solute carrier family 12 member 5 SLC12A5 0.0029
24 Thymidylate synthase TMP1 0.0028
359 Thymidylate synthase TYMS 0.0028
2626 Thymidylate synthase thyA 0.0028
2729 Thymidylate synthase thyA 0.0028
5352 Thymidylate synthase THYA 0.0028
1435 Synaptic vesicle glycoprotein 2A SV2A 0.0028
365 Dihydrofolate reductase DHFR 0.0028
2381 Dihydrofolate reductase DFR1 0.0028
2833 Dihydrofolate reductase Not Available 0.0028
2931 Dihydrofolate reductase folA 0.0028
3544 Dihydrofolate reductase folA 0.0028
3682 Dihydrofolate reductase folA 0.0028
6642 Dihydrofolate reductase folA 0.0028
6756 Dihydrofolate reductase dfrA 0.0028
32 Vascular endothelial growth factor receptor 1 FLT1 0.0028
6014 Cytochrome P450 2A13 CYP2A13 0.0028
489 Monocarboxylate transporter 2 SLC16A7 0.0028
543 Penicillin-binding protein 1B mrcB 0.0028
6186 Penicillin-binding protein 1B ponB 0.0028
6822 Penicillin-binding protein 1b pbp1b 0.0028
6844 Penicillin-binding protein 1b pbp1b 0.0028
6138 Multidrug resistance protein 3 ABCB4 0.0028
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0027
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0027
6232 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short GNAS 0.0027
6233 Adenylate cyclase type 2 ADCY2 0.0027
6234 Adenylate cyclase type 5 ADCY5 0.0027
777 Tumor necrosis factor TNF 0.0027
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0027
412 Peroxisomal carnitine O-octanoyltransferase CROT 0.0027
551 Carnitine O-acetyltransferase CRAT 0.0027
310 Solute carrier family 12 member 2 SLC12A2 0.0027
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0027
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0026
818 50S ribosomal protein L10 rplJ 0.0026
407 Vascular endothelial growth factor receptor 2 KDR 0.0026
228 Beta platelet-derived growth factor receptor PDGFRB 0.0026
6599 HTH-type transcriptional regulator ttgR ttgR 0.0026
273 Apoptosis regulator Bcl-2 BCL2 0.0026
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0026
5997 Tumor necrosis factor ligand superfamily member 11 TNFSF11 0.0026
1852 Microtubule-associated protein 2 MAP2 0.0026
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0025
29 Tubulin beta-1 chain TUBB1 0.0025
1385 Angiotensin-converting enzyme 2 ACE2 0.0025
6044 Serum paraoxonase/lactonase 3 PON3 0.0025
185 Vasopressin V1a receptor AVPR1A 0.0024
432 D(4) dopamine receptor DRD4 0.0024
6432 Transporter snf 0.0024
319 Opioid receptor, sigma 1 OPRS1 0.0024
4148 Serine/threonine-protein kinase mTOR MTOR 0.0024
322 Vasopressin V2 receptor AVPR2 0.0024
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0024
2021 Thrombomodulin THBD 0.0024
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0024
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0024
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.0023
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0023
4103 Proteasome subunit beta type 2 PSMB2 0.0023
4102 Proteasome subunit beta type 5 PSMB5 0.0023
4101 Proteasome subunit beta type 1 PSMB1 0.0023
4221 Vascular endothelial growth factor VEGF 0.0023
5816 Cadherin-5 CDH5 0.0023
572 Integrin alpha-L ITGAL 0.0023
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0023
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0023
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0023
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0023
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0023
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0022
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0022
716 5-hydroxytryptamine 7 receptor HTR7 0.0021
4122 Histone deacetylase 2 HDAC2 0.0021
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0021
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0021
163 D(1B) dopamine receptor DRD5 0.0021
2461 D-alanyl-D-alanine carboxypeptidase Not Available 0.002
5756 D-alanyl-D-alanine carboxypeptidase dac 0.002
5682 Ribonuclease pancreatic RNASE1 0.002
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.002
3929 Phosphoethanolamine/phosphocholine phosphatase PHOSPHO1 0.002
549 Choline-phosphate cytidylyltransferase B PCYT1B 0.002
769 High-affinity choline transporter 1 SLC5A7 0.002
3933 Choline/ethanolaminephosphotransferase CEPT1 0.002
861 Choline kinase alpha CHKA 0.002
700 Choline dehydrogenase, mitochondrial CHDH 0.002
3927 Choline transporter-like protein 3 SLC44A3 0.002
1686 Choline transporter-like protein 1 SLC44A1 0.002
264 Choline/ethanolamine kinase [Includes: Choline kinase beta CHKB 0.002
3926 Choline transporter-like protein 2 SLC44A2 0.002
3925 Choline transporter-like protein 4 SLC44A4 0.002
576 Choline O-acetyltransferase CHAT 0.002
3922 Phospholipase D2 PLD2 0.002
3924 Phospholipase D1 PLD1 0.002
1656 CYP2B protein CYP2B 0.002
1360 Sphingomyelin phosphodiesterase SMPD1 0.002
2107 Microtubule-associated protein 1A MAP1A 0.002
357 Carbonic anhydrase 2 CA2 0.0019
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0019
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0019
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0019
1638 Solute carrier family 2, facilitated glucose transporter member 2 SLC2A2 0.0019
239 Coagulation factor X F10 0.0019
6020 Aldehyde oxidase AOX1 0.0019
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0018
517 Alcohol dehydrogenase 1C ADH1C 0.0018
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0018
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0018
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0018
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0018
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0018
3809 Estrogen-related receptor gamma ESRRG 0.0018
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0018
153 Dopamine beta-hydroxylase DBH 0.0018
6042 Prostaglandin reductase 2 PTGR2 0.0018
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0018
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0017
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0017
5818 Folate receptor alpha FOLR1 0.0017
2391 Ferrochelatase hemH 0.0017
6502 Ferrochelatase DKFZp686P18130 0.0017
1591 Ferrochelatase, mitochondrial FECH 0.0017
1039 Histone deacetylase 9 HDAC9 0.0017
768 FK506-binding protein 1A FKBP1A 0.0017
2539 Tubulin alpha-1 chain TUBA4A 0.0016
1792 Tissue-type plasminogen activator PLAT 0.0016
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0016
6824 Tyrosine-protein kinase Lyn LYN 0.0016
6766 O-GlcNAcase BT_4395 BT_4395 0.0016
5300 Antigen peptide transporter 1 TAP1 0.0016
6043 Putative G-protein coupled receptor 44 GPR44 0.0016
2599 Tyrosine-protein kinase HCK HCK 0.0016
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0016
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0016
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0016
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0016
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0016
816 Biliverdin reductase A BLVRA 0.0016
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0016
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0016
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0016
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0016
2981 Phospholipase A2, membrane associated PLA2G2A 0.0015
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0015
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0015
6755 Poliovirus receptor PVR 0.0015
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0015
702 UMP-CMP kinase CMPK1 0.0015
284 DNA-directed RNA polymerase beta chain rpoB 0.0015
5773 DNA-directed RNA polymerase beta chain rpoB 0.0015
293 Gamma-glutamyl hydrolase GGH 0.0015
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0015
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0015
6493 Cytochrome c oxidase subunit 6C COX6C 0.0015
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.0015
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.0015
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.0015
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.0015
605 Fumarate reductase flavoprotein subunit frdA 0.0015
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0015
3673 Fumarate reductase flavoprotein subunit fccA 0.0015
4912 Fumarate reductase flavoprotein subunit ifcA 0.0015
6549 Fumarate reductase flavoprotein subunit frdA 0.0015
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.0015
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.0015
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.0015
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.0015
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0015
6559 Cytochrome c oxidase subunit 2 ctaC 0.0015
6669 Cytochrome c oxidase subunit 2 ctaC 0.0015
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.0015
371 Cytochrome c oxidase subunit 1 MT-CO1 0.0015
6558 Cytochrome c oxidase subunit 1 ctaD 0.0015
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0015
165 FL cytokine receptor FLT3 0.0015
1770 Phospholipase C PLCL1 0.0015
2841 Phospholipase C plc 0.0015
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0015
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.0014
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.0014
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.0014
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.0014
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.0014
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.0014
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.0014
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.0014
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.0014
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.0014
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.0014
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.0014
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.0014
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.0014
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.0014
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.0014
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.0014
602 Acyl carrier protein, mitochondrial NDUFAB1 0.0014
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.0014
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.0014
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.0014
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.0014
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.0014
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.0014
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.0014
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.0014
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.0014
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.0014
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.0014
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.0014
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.0014
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.0014
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.0014
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.0014
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.0014
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.0014
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.0014
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.0014
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.0014
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.0014
662 Fatty aldehyde dehydrogenase ALDH3A2 0.0014
644 Heme oxygenase 2 HMOX2 0.0014
4982 Heme oxygenase 2 pbsA2 0.0014
167 L-lactate dehydrogenase C chain LDHC 0.0014
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0014
3726 D-3-phosphoglycerate dehydrogenase serA 0.0014
4291 D-3-phosphoglycerate dehydrogenase serA 0.0014
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.0014
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.0014
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.0014
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.0014
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.0014
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.0014
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.0014
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.0014
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.0014
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.0014
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.0014
729 GDP-L-fucose synthetase TSTA3 0.0014
3463 GDP-L-fucose synthetase fcl 0.0014
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.0014
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.0014
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.0014
34 7-dehydrocholesterol reductase DHCR7 0.0014
711 UDP-glucose 6-dehydrogenase UGDH 0.0014
3672 UDP-glucose 6-dehydrogenase hasB 0.0014
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.0014
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.0014
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.0014
107 C-4 methylsterol oxidase SC4MOL 0.0014
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.0014
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.0014
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.0014
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.0014
206 3-keto-steroid reductase HSD17B7 0.0014
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.0014
643 Peroxisomal bifunctional enzyme EHHADH 0.0014
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.0014
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.0014
1178 Adenosine A2a receptor ADORA2A 0.0014
646 Malate dehydrogenase, cytoplasmic MDH1 0.0014
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0014
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0014
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0014
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0014
396 Alcohol dehydrogenase 4 ADH4 0.0014
328 Sorbitol dehydrogenase SORD 0.0014
2129 Sucrase-isomaltase, intestinal SI 0.0014
597 Dihydropteridine reductase QDPR 0.0014
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0014
1629 Transcription factor AP-1 JUN 0.0014
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0014
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0014
666 NADP-dependent malic enzyme ME1 0.0014
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0014
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0014
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0014
444 Alcohol dehydrogenase 1B ADH1B 0.0014
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0014
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0014
1313 Lactoylglutathione lyase GLO1 0.0014
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0014
2540 Choloylglycine hydrolase cbh 0.0014
1650 Heme carrier protein 1 SLC46A1 0.0013
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0013
857 Malate dehydrogenase, mitochondrial MDH2 0.0013
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0013
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0013
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0013
77 L-lactate dehydrogenase B chain LDHB 0.0013
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0013
12 Alcohol dehydrogenase class 3 ADH5 0.0013
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0013
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0013
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0013
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0013
528 5-hydroxytryptamine 1E receptor HTR1E 0.0013
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0013
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0013
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0013
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0013
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0013
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.0013
6501 Fatty acid-binding protein, liver FABP1 0.0013
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0013
473 L-lactate dehydrogenase A chain LDHA 0.0013
4773 Deoxycytidine kinase DCK 0.0012
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0012
3856 Fibroblast growth factor receptor 3 FGFR3 0.0012
3382 Glycolipid transfer protein GLTP 0.0012
6026 Alcohol dehydrogenase 6 ADH6 0.0012
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0012
627 11-cis retinol dehydrogenase RDH5 0.0012
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0012
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.0012
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0012
694 Matrix protein 2 M 0.0012
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0012
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0012
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0012
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0012
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0012
2297 Genome polyprotein Not Available 0.0012
2322 Genome polyprotein Not Available 0.0012
2694 Genome polyprotein Not Available 0.0012
2719 Genome polyprotein Not Available 0.0012
2860 Genome polyprotein Not Available 0.0012
2928 Genome polyprotein Not Available 0.0012
3160 Genome polyprotein Not Available 0.0012
3260 Genome polyprotein Not Available 0.0012
4783 Genome polyprotein Not Available 0.0012
5726 Genome polyprotein Not Available 0.0012
5779 Genome polyprotein Not Available 0.0012
5867 Genome polyprotein Not Available 0.0012
6253 Genome polyprotein Not Available 0.0012
6301 Genome polyprotein Not Available 0.0012
6380 Genome polyprotein Not Available 0.0012
6381 Genome polyprotein Not Available 0.0012
6437 Genome polyprotein Not Available 0.0012
6520 Genome polyprotein Not Available 0.0012
6521 Genome polyprotein Not Available 0.0012
6652 Genome polyprotein Not Available 0.0012
6734 Genome polyprotein Not Available 0.0012
6735 Genome polyprotein Not Available 0.0012
6736 Genome polyprotein Not Available 0.0012
6737 Genome polyprotein Not Available 0.0012
6738 Genome polyprotein Not Available 0.0012
6739 Genome polyprotein Not Available 0.0012
6744 Genome polyprotein Not Available 0.0012
6748 Genome polyprotein Not Available 0.0012
6894 Genome polyprotein Not Available 0.0012
6898 Genome polyprotein Not Available 0.0012
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0012
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0012
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0012
569 Retinal dehydrogenase 2 ALDH1A2 0.0012
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.0012
13 Aminomethyltransferase, mitochondrial AMT 0.0012
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0012
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0012
626 Cysteine dioxygenase type 1 CDO1 0.0012
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0012
461 Glycine receptor subunit alpha-3 GLRA3 0.0012
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0012
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0012
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0012
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0012
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.0012
6859 Protein S100-A4 S100A4 0.0012
611 Retinal dehydrogenase 1 ALDH1A1 0.0012
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0012
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0011
707 72 kDa type IV collagenase MMP2 0.0011
2112 Toll-like receptor 9 TLR9 0.0011
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0011
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0011
5923 Microtubule-associated protein tau MAPT 0.0011
5924 Microtubule-associated protein 4 MAP4 0.0011
251 Alcohol dehydrogenase 1A ADH1A 0.0011
3917 Methylenetetrahydrofolate reductase MTHFR 0.0011
6459 Glycodelin PAEP 0.0011
654 Flavin reductase BLVRB 0.0011
1618 High affinity nerve growth factor receptor NTRK1 0.0011
427 Substance-P receptor TACR1 0.0011
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0011
6500 Phospholipase A2 PLA2G1B 0.0011
810 Heme oxygenase 1 HMOX1 0.001
3391 Heme oxygenase 1 pbsA1 0.001
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.001
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.001
144 Hemoglobin subunit alpha HBA1 0.001
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.001
279 Tyrosinase TYR 0.001
106 Cannabinoid receptor 2 CNR2 0.001
6174 50S ribosomal protein L32 rpmF 0.001
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.001
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.001
811 Translocator protein TSPO 0.001
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.001
2473 Tyrosine-protein kinase CSK CSK 0.001
2398 Tyrosine-protein kinase ZAP-70 ZAP70 0.001
476 RAC-alpha serine/threonine-protein kinase AKT1 0.001
890 Niemann-Pick C1-like protein 1 NPC1L1 0.001
68 Cannabinoid receptor 1 CNR1 0.001
65 Matrix metalloproteinase-9 Not Available 0.001
714 Glutathione reductase, mitochondrial GSR 0.001
4192 DNA topoisomerase 2-beta TOP2B 0.001
3957 Adenosine deaminase ADA 0.0009
936 Ephrin type-A receptor 2 EPHA2 0.0009
3611 Cytidine deaminase cdd 0.0009
3707 Cytidine deaminase cdd 0.0009
4211 Cytidine deaminase CDA 0.0009
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0009
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0009
1525 Heparin-binding growth factor 2 FGF2 0.0009
360 Ribonucleoside-diphosphate reductase large subunit RRM1 0.0009
1569 G1/S-specific cyclin-D1 CCND1 0.0009
2240 Cell division protein kinase 2 CDK2 0.0009
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0009
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0009
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0009
1760 Aminopeptidase N ANPEP 0.0009
6843 Aminopeptidase N pepN 0.0009
992 Protein tyrosine kinase 2 beta PTK2B 0.0009
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0009
6171 Solute carrier family 28 member 3 SLC28A3 0.0009
54 Prothrombin F2 0.0009
3932 Glutathione S-transferase A2 GSTA2 0.0009
1262 Corticotropin-lipotropin POMC 0.0009
117 Sterol O-acyltransferase 1 SOAT1 0.0008
5787 Angiopoietin-1 receptor TEK 0.0008
822 Aldose reductase AKR1B1 0.0008
823 Fibroblast growth factor receptor 2 FGFR2 0.0008
3616 Fatty acid-binding protein, epidermal FABP5 0.0008
5433 UPF0230 protein TM_1468 TM_1468 0.0008
5430 Hepatocyte nuclear factor 4-gamma HNF4G 0.0008
5431 Lipid binding protein Not Available 0.0008
6211 Tubulin epsilon chain TUBE1 0.0008
6212 Tubulin gamma-1 chain TUBG1 0.0008
6210 Tubulin delta chain TUBD1 0.0008
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0008
229 Retinoic acid receptor beta RARB 0.0008
484 Tyrosine-protein kinase ABL2 ABL2 0.0008
780 Retinoic acid receptor RXR-gamma RXRG 0.0008
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0008
730 Retinoic acid receptor alpha RARA 0.0008
908 Glutathione S-transferase theta-1 GSTT1 0.0008
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0008
2530 Protein kinase C theta type PRKCQ 0.0008
1714 Mitogen-activated protein kinase 3 MAPK3 0.0008
459 Retinoic acid receptor RXR-alpha RXRA 0.0007
88 Retinoic acid receptor RXR-beta RXRB 0.0007
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0007
162 Retinoic acid receptor gamma-1 RARG 0.0007
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0007
283 SEC14-like protein 2 SEC14L2 0.0007
2408 Tyrosine-protein kinase SYK SYK 0.0007
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0007
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.0007
6837 Serine/threonine-protein kinase 17B STK17B 0.0007
1256 5-hydroxytryptamine 6 receptor HTR6 0.0007
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0007
2211 Fatty acid-binding protein, heart FABP3 0.0007
1374 Natriuretic peptides B NPPB 0.0006
1827 Gap junction alpha-1 protein GJA1 0.0006
1908 Vascular cell adhesion protein 1 VCAM1 0.0006
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0006
2216 Fibroblast growth factor receptor 4 FGFR4 0.0006
1063 Signal transducer and activator of transcription 5B STAT5B 0.0006
4217 Telomerase reverse transcriptase TERT 0.0006
814 Ryanodine receptor 1 RYR1 0.0006
6677 Myelin P2 protein PMP2 0.0006
6241 Nuclear receptor coactivator 2 NCOA2 0.0006
342 P protein [Includes: DNA-directed DNA polymerase P 0.0006
612 P protein [Includes: DNA-directed DNA polymerase P 0.0006
1176 Mitogen-activated protein kinase 1 MAPK1 0.0006
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0006
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0006
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0006
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0006
174 Sigma 1-type opioid receptor SIGMAR1 0.0006
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0006
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0006
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0006
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0006
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0006
5626 Nucleoside diphosphate kinase B NME2 0.0005
1721 Glycogen synthase kinase-3 beta GSK3B 0.0005
3238 Multidrug resistance protein mexA mexA 0.0005
3116 Bacterioferritin bfr 0.0005
4906 Bacterioferritin bfr 0.0005
4965 Bacterioferritin bfr 0.0005
3173 Enolase eno 0.0005
3709 Glycerol uptake facilitator protein glpF 0.0005
3336 C4-dicarboxylate transport transcriptional regulatory protein dctD dctD 0.0005
3393 TGF-beta receptor type-2 TGFBR2 0.0005
5489 Ribonucleoside-diphosphate reductase 1 subunit beta nrdB 0.0005
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.0005
2207 Rhodopsin RHO 0.0005
5798 Mitogen-activated protein kinase 11 MAPK11 0.0005
183 Vascular endothelial growth factor A VEGFA 0.0005
2183 Fatty acid-binding protein, adipocyte FABP4 0.0005
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0005
16 Adenosine A1 receptor ADORA1 0.0005
2320 Thymidine kinase, cytosolic TK1 0.0005
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0005
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0005
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0005
233 Potassium channel subfamily K member 2 KCNK2 0.0005
1864 RET proto-oncogene RET 0.0005
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0005
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0005
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0005
2852 DNA mismatch repair protein mutL mutL 0.0005
1275 Estrogen sulfotransferase SULT1E1 0.0005
760 Fibroblast growth factor 1 FGF1 0.0005
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0005
3191 Histidinol dehydrogenase hisD 0.0005
3221 Cytochrome c4 cc4 0.0005
5294 Nucleoside diphosphate kinase A NME1 0.0005
6102 Arylamine N-acetyltransferase 2 NAT2 0.0004
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0004
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0004
4311 tRNA TRDMT1 0.0004
4325 tRNA trmD 0.0004
4328 tRNA trmD 0.0004
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0004
4692 A/G-specific adenine glycosylase mutY 0.0004
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0004
6163 Copper-transporting ATPase 2 ATP7B 0.0004
6165 Copper-transporting ATPase 1 ATP7A 0.0004
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0004
2802 Endoglucanase G celCCG 0.0004
340 Apoptotic protease-activating factor 1 APAF1 0.0004
6146 High affinity copper uptake protein 1 SLC31A1 0.0004
6316 ADP-ribosylation factor 1 ARF1 0.0004
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0004
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0004
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0004
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0003
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0003
825 Arsenical pump-driving ATPase ASNA1 0.0003
3435 Arsenical pump-driving ATPase arsA 0.0003
486 Serine/threonine-protein kinase ALS2CR7 CDK15 0.0003
2105 ATP-binding cassette sub-family G member 1 ABCG1 0.0003
377 Beta-adrenergic receptor kinase 1 ADRBK1 0.0003
510 Serine/threonine-protein kinase receptor R3 ACVRL1 0.0003
733 Activin receptor type 1B ACVR1B 0.0003
225 NEDD8-activating enzyme E1 regulatory subunit NAE1 0.0003
745 Anti-Muellerian hormone type-2 receptor AMHR2 0.0003
483 A-Raf proto-oncogene serine/threonine-protein kinase ARAF 0.0003
21 Beta-adrenergic receptor kinase 2 ADRBK2 0.0003
154 AFG3-like protein 2 AFG3L2 0.0003
395 ALK tyrosine kinase receptor Not Available 0.0003
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0003
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0003
896 Glutathione S-transferase Mu 1 GSTM1 0.0003
295 Carbonic anhydrase 1 CA1 0.0003
292 Activin receptor type-1 ACVR1 0.0003
849 Activated CDC42 kinase 1 TNK2 0.0003
704 Long-chain-fatty-acid--CoA ligase 1 ACSL1 0.0003
821 Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 0.0003
386 Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 0.0003
297 Adenylate cyclase type 1 ADCY1 0.0003
289 Cytosolic purine 5'-nucleotidase NT5C2 0.0003
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0003
275 Arachidonate 5-lipoxygenase ALOX5 0.0003
76 Nitric-oxide synthase, brain NOS1 0.0002
661 ADP/ATP translocase 1 SLC25A4 0.0002
6021 Adenosine kinase ADK 0.0002
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0002
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0002
921 Glutamate receptor 2 GRIA2 0.0002
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