DT-Web

DB00967 - Desloratadine


Identification
Name Desloratadine
Accession Number DB00967 (APRD00324)
Type small molecule
Description Desloratadine is a second generation, tricyclic antihistamine that which has a selective and peripheral H1-antagonist action. It is the active descarboethoxy metabolite of loratidine (a second generation histamine). Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system.
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 310.821
Groups approved
Monoisotopic Weight 310.123676325
Pharmacology
Indication For the relief of symptoms of seasonal allergic rhinitis, perennial (non-seasonal) allergic rhinitis. Desloratidine is also used for the sympomatic treatment of pruritus and urticaria (hives) associated with chronic idiopathic urticaria.
Mechanism of action Like other H1-blockers, Desloratadine competes with free histamine for binding at H1-receptors in the GI tract, uterus, large blood vessels, and bronchial smooth muscle. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms (eg. nasal congestion, watery eyes) brought on by histamine.
Absorption Not Available
Protein binding 82-87%
Biotransformation Not Available
Route of elimination Desloratadine (a major metabolite of loratadine) is extensively metabolized to 3-hydroxydesloratadine, an active metabolite, which is subsequently glucuronidated. Approximately 87% of a 14C-desloratadine dose was equally recovered in urine and feces.
Toxicity Not Available
Affected organisms
  • Humans and other mammals
Interactions
Drug Interactions
Drug Mechanism of interaction
Tacrine The therapeutic effects of the central acetylcholinesterase inhibitor, Tacrine, and/or the anticholinergic, Desloratadine, may be reduced due to antagonism. The interaction may be beneficial when the anticholinergic action is a side effect. Monitor for decreased efficacy of both agents.
Triprolidine Triprolidine and Desloratadine, two anticholinergics, may cause additive anticholinergic effects and enhance their adverse/toxic effects. Additive CNS depressant effects may also occur. Monitor for enhanced anticholinergic and CNS depressant effects.
Trospium Trospium and Desloratadine, two anticholinergics, may cause additive anticholinergic effects and enhanced adverse/toxic effects. Monitor for enhanced anticholinergic effects.
Food Interactions
  • Take without regard to meals.

Targets


Histamine H1 receptor
Name Histamine H1 receptor
Gene Name HRH1
Pharmacological action yes
Actions antagonist
References
  • Wu RL, Anthes JC, Kreutner W, Harris AG, West RE Jr: Desloratadine inhibits constitutive and histamine-stimulated nuclear factor-kappaB activity consistent with inverse agonism at the histamine H1 Receptor. Int Arch Allergy Immunol. 2004 Dec;135(4):313-8. Epub 2004 Nov 24. - Pubmed
  • Cieslewicz G, Gondorowicz K, Grzelewska-Rzymowska I, Rozniecki J: [Effect of loratadine, selective antagonist of histamine H1 receptors, on histamine-induced bronchoconstriction] Pneumonol Alergol Pol. 1995;63(5-6):281-5. - Pubmed
  • Letari O, Miozzo A, Folco G, Belloni PA, Sala A, Rovati GE, Nicosia S: Effects of loratadine on cytosolic Ca2+ levels and leukotriene release: novel mechanisms of action independent of the anti-histamine activity. Eur J Pharmacol. 1994 Feb 15;266(3):219-27. - Pubmed
  • Chen X, Ji ZL, Chen YZ: TTD: Therapeutic Target Database. Nucleic Acids Res. 2002 Jan 1;30(1):412-5. - Pubmed
  • Devillier P, Roche N, Faisy C: Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review. Clin Pharmacokinet. 2008;47(4):217-30. - Pubmed
  • DuBuske L: Desloratadine for chronic idiopathic urticaria: a review of clinical efficacy. Am J Clin Dermatol. 2007;8(5):271-83. - Pubmed
  • Simons FE, Prenner BM, Finn A Jr: Efficacy and safety of desloratadine in the treatment of perennial allergic rhinitis. J Allergy Clin Immunol. 2003 Mar;111(3):617-22. - Pubmed
  • Dhanya NB, Thasleem Z, Rai R, Srinivas CR: Comparative efficacy of levocetirizine, desloratidine and fexofenadine by histamine wheal suppression test. Indian J Dermatol Venereol Leprol. 2008 Jul-Aug;74(4):361-3. - Pubmed
DTHybrid score 0.5384

Enzymes


Cytochrome P450 2C19
Name Cytochrome P450 2C19
Gene Name CYP2C19
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3667
Cytochrome P450 1A2
Name Cytochrome P450 1A2
Gene Name CYP1A2
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3881
Cytochrome P450 2D6
Name Cytochrome P450 2D6
Gene Name CYP2D6
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.463
Cytochrome P450 2C9
Name Cytochrome P450 2C9
Gene Name CYP2C9
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4094

Transporters


Multidrug resistance protein 1
Name Multidrug resistance protein 1
Gene Name ABCB1
Actions inhibitor
References
  • Wang EJ, Casciano CN, Clement RP, Johnson WW: Evaluation of the interaction of loratadine and desloratadine with P-glycoprotein. Drug Metab Dispos. 2001 Aug;29(8):1080-3. - Pubmed
DTHybrid score 0.3458

Predictions


Id Partner name Gene Name Score
4512 Cytochrome P450 3A4 CYP3A4 0.3958
4924 Cytochrome P450 2C8 CYP2C8 0.1977
4118 Cytochrome P450 3A5 CYP3A5 0.1587
6030 Cytochrome P450 2B6 CYP2B6 0.1482
6013 Cytochrome P450 2E1 CYP2E1 0.1306
6107 Cytochrome P450 3A7 CYP3A7 0.1157
6024 Cytochrome P450 1A1 CYP1A1 0.1046
5718 Cytochrome P450 2A6 CYP2A6 0.0844
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0771
587 Serum albumin ALB 0.0765
20 Prostaglandin G/H synthase 1 PTGS1 0.0758
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0709
824 Sodium-dependent serotonin transporter SLC6A4 0.0698
556 Alpha-1A adrenergic receptor ADRA1A 0.0695
502 5-hydroxytryptamine 2A receptor HTR2A 0.0677
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0613
831 D(2) dopamine receptor DRD2 0.0599
1181 Alpha-1-acid glycoprotein 1 ORM1 0.0544
713 Sodium-dependent dopamine transporter SLC6A3 0.0503
6106 Cytochrome P450 2C18 CYP2C18 0.0494
318 Alpha-2A adrenergic receptor ADRA2A 0.0493
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0487
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0485
6145 Solute carrier family 22 member 1 SLC22A1 0.0472
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0467
590 5-hydroxytryptamine 2C receptor HTR2C 0.0464
51 Muscarinic acetylcholine receptor M3 CHRM3 0.045
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0436
1729 Solute carrier family 22 member 6 SLC22A6 0.0428
23 D(1A) dopamine receptor DRD1 0.0424
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0416
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0405
862 Multidrug resistance-associated protein 1 ABCC1 0.0405
290 Prostaglandin G/H synthase 2 PTGS2 0.0403
6144 Solute carrier family 22 member 2 SLC22A2 0.0401
766 Beta-2 adrenergic receptor ADRB2 0.04
320 5-hydroxytryptamine 1A receptor HTR1A 0.0398
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0396
193 Beta-1 adrenergic receptor ADRB1 0.0386
632 Alpha-1B adrenergic receptor ADRA1B 0.0384
118 Organic cation/carnitine transporter 2 SLC22A5 0.0353
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0336
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0335
1898 Cytochrome P450 1B1 CYP1B1 0.0323
3941 Amine oxidase [flavin-containing] A MAOA 0.0305
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.03
3811 Cytochrome P450 19A1 CYP19A1 0.0296
638 D(3) dopamine receptor DRD3 0.0281
341 5-hydroxytryptamine 3 receptor HTR3A 0.0275
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0266
885 5-hydroxytryptamine 1B receptor HTR1B 0.0259
36 Insulin receptor INSR 0.0258
789 Alpha-1D adrenergic receptor ADRA1D 0.0257
629 Alpha-2B adrenergic receptor ADRA2B 0.0255
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0254
776 Bile salt export pump ABCB11 0.025
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.025
817 DNA topoisomerase 2-alpha TOP2A 0.0247
731 HIV-1 protease HIV-1 protease 0.0245
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0245
465 Calmodulin CALM1 0.0239
432 D(4) dopamine receptor DRD4 0.0237
3939 Amine oxidase [flavin-containing] B MAOB 0.0237
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.0234
725 5-hydroxytryptamine 1D receptor HTR1D 0.0233
136 Estrogen receptor ESR1 0.0224
847 Mu-type opioid receptor OPRM1 0.0223
833 Organic cation/carnitine transporter 1 SLC22A4 0.0218
378 Alpha-2C adrenergic receptor ADRA2C 0.0217
6142 Solute carrier family 22 member 8 SLC22A8 0.0216
696 Kappa-type opioid receptor OPRK1 0.0209
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0206
6143 Solute carrier family 22 member 7 SLC22A7 0.0203
3923 Cholinesterase BCHE 0.0203
260 Cytochrome P450 51 ERG11 0.0202
761 Cytochrome P450 51 ERG11 0.0202
3163 Cytochrome P450 51 cyp51 0.0202
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0201
6182 Cytochrome P450 2J2 CYP2J2 0.0199
2164 Multidrug resistance-associated protein 4 ABCC4 0.0198
124 Histamine H2 receptor HRH2 0.0198
467 Delta-type opioid receptor OPRD1 0.0196
1341 Histamine H3 receptor HRH3 0.0193
6147 Solute carrier family 22 member 3 SLC22A3 0.019
436 5-hydroxytryptamine 2B receptor HTR2B 0.0182
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.018
122 P2Y purinoceptor 12 P2RY12 0.0174
1656 CYP2B protein CYP2B 0.0174
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0174
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0173
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0169
516 Neurotensin receptor type 2 NTSR2 0.0168
716 5-hydroxytryptamine 7 receptor HTR7 0.0166
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0164
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0163
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0163
477 DNA topoisomerase 4 subunit A parC 0.0163
886 DNA topoisomerase 4 subunit A parC 0.0163
6226 DNA topoisomerase 4 subunit A parC 0.0163
404 DNA gyrase subunit A gyrA 0.016
6224 DNA gyrase subunit A gyrA 0.016
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.016
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0159
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0159
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0153
871 Glucocorticoid receptor NR3C1 0.0153
468 Cytochrome P450 4A11 CYP4A11 0.0147
891 Dihydropteroate synthase folP 0.0144
5359 Dihydropteroate synthase folP 0.0144
7175 Dihydropteroate synthase sulI 0.0144
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0142
70 Type-1 angiotensin II receptor AGTR1 0.0139
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0137
1275 Estrogen sulfotransferase SULT1E1 0.0136
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0134
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0132
163 D(1B) dopamine receptor DRD5 0.0131
6031 Cytochrome P450 3A43 CYP3A43 0.013
146 Androgen receptor AR 0.0129
777 Tumor necrosis factor TNF 0.0125
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0123
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0122
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0122
1256 5-hydroxytryptamine 6 receptor HTR6 0.0121
474 Acetylcholinesterase ACHE 0.012
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0118
844 Epidermal growth factor receptor EGFR 0.0117
4604 Liver carboxylesterase 1 CES1 0.0115
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0115
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.0114
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.0114
1024 Solute carrier family 22 member 11 SLC22A11 0.0113
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.0113
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0112
238 Peroxisome proliferator-activated receptor gamma PPARG 0.011
571 Melatonin receptor type 1A MTNR1A 0.011
362 Melatonin receptor type 1B MTNR1B 0.011
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0109
380 Cytochrome P450 17A1 CYP17A1 0.0109
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0108
6137 Multidrug resistance-associated protein 6 ABCC6 0.0108
504 Mast/stem cell growth factor receptor KIT 0.0107
6148 Multidrug resistance-associated protein 7 ABCC10 0.0107
6220 Aryl hydrocarbon receptor AHR 0.0104
528 5-hydroxytryptamine 1E receptor HTR1E 0.0103
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0103
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0099
6136 Multidrug resistance-associated protein 5 ABCC5 0.0097
958 Insulin-like growth factor 1 receptor IGF1R 0.0097
4120 NADPH--cytochrome P450 reductase POR 0.0096
1178 Adenosine A2a receptor ADORA2A 0.0095
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0092
6141 Sodium/bile acid cotransporter SLC10A1 0.0092
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0092
407 Vascular endothelial growth factor receptor 2 KDR 0.0091
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.0091
161 Tubulin beta chain TUBB 0.0091
312 Tubulin beta chain TUB2 0.0091
26 Vascular endothelial growth factor receptor 3 FLT4 0.009
1757 Myeloperoxidase MPO 0.009
94 5-hydroxytryptamine 4 receptor HTR4 0.009
16 Adenosine A1 receptor ADORA1 0.0089
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0089
869 Estrogen receptor beta ESR2 0.0089
1192 Sulfotransferase 1A1 SULT1A1 0.0087
32 Vascular endothelial growth factor receptor 1 FLT1 0.0086
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0084
6014 Cytochrome P450 2A13 CYP2A13 0.0083
365 Dihydrofolate reductase DHFR 0.0083
2381 Dihydrofolate reductase DFR1 0.0083
2833 Dihydrofolate reductase Not Available 0.0083
2931 Dihydrofolate reductase folA 0.0083
3544 Dihydrofolate reductase folA 0.0083
3682 Dihydrofolate reductase folA 0.0083
6642 Dihydrofolate reductase folA 0.0083
6756 Dihydrofolate reductase dfrA 0.0083
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.0083
614 Progesterone receptor PGR 0.0083
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0083
228 Beta platelet-derived growth factor receptor PDGFRB 0.0082
373 Transthyretin TTR 0.0081
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0079
442 Envelope glycoprotein gp41 0.0078
4859 Envelope glycoprotein env 0.0078
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0075
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0075
756 Sex hormone-binding globulin SHBG 0.0075
3947 Xanthine dehydrogenase/oxidase XDH 0.0075
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.0075
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.0075
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0074
6102 Arylamine N-acetyltransferase 2 NAT2 0.0074
6432 Transporter snf 0.0073
1010 Cytochrome P450 51A1 CYP51A1 0.0073
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0073
511 5-hydroxytryptamine 1F receptor HTR1F 0.0072
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0072
244 Angiotensin-converting enzyme ACE 0.0071
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0071
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0071
49 Endothelin B receptor EDNRB 0.007
818 50S ribosomal protein L10 rplJ 0.007
4203 Histamine N-methyltransferase HNMT 0.007
427 Substance-P receptor TACR1 0.0069
3810 Catechol O-methyltransferase COMT 0.0069
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.0067
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.0067
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.0067
578 Endothelin-1 receptor EDNRA 0.0066
259 Microsomal triglyceride transfer protein large subunit MTTP 0.0065
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0065
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0065
592 Carbonic anhydrase 4 CA4 0.0065
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0065
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0064
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0064
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0064
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0064
183 Vascular endothelial growth factor A VEGFA 0.0063
3432 Multidrug-efflux transporter 1 regulator bmrR 0.0063
131 Synaptic vesicular amine transporter SLC18A2 0.0063
4476 Mannitol dehydrogenase mtlD 0.0063
952 Dipeptidyl peptidase 4 DPP4 0.0063
173 Toll-like receptor 7 TLR7 0.0063
133 Dihydropterate synthase sulI 0.0063
295 Carbonic anhydrase 1 CA1 0.0063
738 Monocarboxylate transporter 1 SLC16A1 0.0063
565 Extracellular calcium-sensing receptor CASR 0.0062
164 Histamine H4 receptor HRH4 0.0062
4116 Dihydropteroate synthetase Not Available 0.0062
4122 Histone deacetylase 2 HDAC2 0.0062
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0062
811 Translocator protein TSPO 0.0062
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0061
1517 Beta-3 adrenergic receptor ADRB3 0.0061
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0061
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0061
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0061
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0061
273 Apoptosis regulator Bcl-2 BCL2 0.0061
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0061
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.006
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.006
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0059
1618 High affinity nerve growth factor receptor NTRK1 0.0059
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0058
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0056
6085 Fatty acid-binding protein, intestinal FABP2 0.0056
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0055
2112 Toll-like receptor 9 TLR9 0.0055
921 Glutamate receptor 2 GRIA2 0.0055
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0054
2449 Tubulin alpha-3 chain TUBA1A 0.0054
992 Protein tyrosine kinase 2 beta PTK2B 0.0054
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0053
4103 Proteasome subunit beta type 2 PSMB2 0.0052
4102 Proteasome subunit beta type 5 PSMB5 0.0052
4101 Proteasome subunit beta type 1 PSMB1 0.0052
1629 Transcription factor AP-1 JUN 0.0052
24 Thymidylate synthase TMP1 0.0052
359 Thymidylate synthase TYMS 0.0052
2626 Thymidylate synthase thyA 0.0052
2729 Thymidylate synthase thyA 0.0052
5352 Thymidylate synthase THYA 0.0052
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0051
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0051
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0051
6044 Serum paraoxonase/lactonase 3 PON3 0.0051
823 Fibroblast growth factor receptor 2 FGFR2 0.005
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.005
6097 Protein S100-A2 S100A2 0.005
1810 Protein S100-A1 S100A1 0.005
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.005
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.005
482 Glycine receptor subunit alpha-1 GLRA1 0.005
1353 DNA topoisomerase 1 TOP1 0.005
3552 DNA topoisomerase 1 topA 0.005
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0049
737 Mineralocorticoid receptor NR3C2 0.0049
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0049
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0048
275 Arachidonate 5-lipoxygenase ALOX5 0.0048
360 Ribonucleoside-diphosphate reductase large subunit RRM1 0.0048
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0048
357 Carbonic anhydrase 2 CA2 0.0048
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0048
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0048
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0047
6126 Carbonic anhydrase 7 CA7 0.0047
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0047
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0047
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0047
319 Opioid receptor, sigma 1 OPRS1 0.0047
2616 Ganglioside GM2 activator GM2A 0.0047
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0046
2499 Tubulin beta-2C chain TUBB2C 0.0046
518 Peroxidase/catalase T katG 0.0046
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0045
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0045
527 Prostacyclin receptor PTGIR 0.0045
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0045
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0045
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0044
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0044
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0043
239 Coagulation factor X F10 0.0043
1048 Protein S100-A13 S100A13 0.0043
2226 Protein S100-A12 S100A12 0.0043
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0043
563 Thyroid peroxidase TPO 0.0043
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0042
714 Glutathione reductase, mitochondrial GSR 0.0042
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0042
904 Glutathione S-transferase P GSTP1 0.0042
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0041
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0041
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0041
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0041
4238 50S ribosomal protein L4 rplD 0.004
5578 50S ribosomal protein L4 rplD 0.004
6173 50S ribosomal protein L4 rplD 0.004
6219 50S ribosomal protein L4 rplD 0.004
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.004
634 Squalene monooxygenase SQLE 0.004
7196 Squalene monooxygenase ERG1 0.004
2132 Protein S100-B S100B 0.004
4311 tRNA TRDMT1 0.004
4325 tRNA trmD 0.004
4328 tRNA trmD 0.004
1638 Solute carrier family 2, facilitated glucose transporter member 2 SLC2A2 0.004
6146 High affinity copper uptake protein 1 SLC31A1 0.004
3957 Adenosine deaminase ADA 0.004
174 Sigma 1-type opioid receptor SIGMAR1 0.0039
459 Retinoic acid receptor RXR-alpha RXRA 0.0039
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0039
4209 ATP-sensitive inward rectifier potassium channel 8 KCNJ8 0.0038
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0038
2539 Tubulin alpha-1 chain TUBA4A 0.0038
780 Retinoic acid receptor RXR-gamma RXRG 0.0038
117 Sterol O-acyltransferase 1 SOAT1 0.0038
605 Fumarate reductase flavoprotein subunit frdA 0.0038
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0038
3673 Fumarate reductase flavoprotein subunit fccA 0.0038
4912 Fumarate reductase flavoprotein subunit ifcA 0.0038
6549 Fumarate reductase flavoprotein subunit frdA 0.0038
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0038
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0038
54 Prothrombin F2 0.0038
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0038
4148 Serine/threonine-protein kinase mTOR MTOR 0.0038
6138 Multidrug resistance protein 3 ABCB4 0.0038
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0037
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0037
4237 50S ribosomal protein L22 rplV 0.0037
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0037
29 Tubulin beta-1 chain TUBB1 0.0037
5300 Antigen peptide transporter 1 TAP1 0.0037
130 Prostacyclin synthase PTGIS 0.0037
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0036
976 Platelet glycoprotein IX GP9 0.0036
165 FL cytokine receptor FLT3 0.0036
4228 Keratin, type II cytoskeletal 7 KRT7 0.0036
153 Dopamine beta-hydroxylase DBH 0.0035
6149 Solute carrier family 22 member 10 SLC22A10 0.0035
2300 Lysozyme E 0.0035
3633 Lysozyme R 0.0035
5597 Lysozyme 17 0.0035
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.0035
88 Retinoic acid receptor RXR-beta RXRB 0.0035
5998 Toll-like receptor 8 TLR8 0.0035
6217 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B PDE8B 0.0035
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0035
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0035
6766 O-GlcNAcase BT_4395 BT_4395 0.0034
106 Cannabinoid receptor 2 CNR2 0.0034
712 Tubulin alpha chain TUB1 0.0034
6174 50S ribosomal protein L32 rpmF 0.0034
558 Solute carrier family 12 member 1 SLC12A1 0.0033
6506 Stathmin-4 STMN4 0.0033
33 Cystine/glutamate transporter SLC7A11 0.0033
65 Matrix metalloproteinase-9 Not Available 0.0033
613 Atrial natriuretic peptide receptor A NPR1 0.0033
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0033
1648 Elastin ELN 0.0032
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0032
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0032
2981 Phospholipase A2, membrane associated PLA2G2A 0.0032
68 Cannabinoid receptor 1 CNR1 0.0032
3856 Fibroblast growth factor receptor 3 FGFR3 0.0032
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0032
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0031
1636 Trace amine-associated receptor 1 TAAR1 0.0031
1227 Cytochrome b MT-CYB 0.0031
6386 Cytochrome b petB 0.0031
6937 Cytochrome b MT-CYB 0.0031
674 Dihydroorotate dehydrogenase homolog, mitochondrial PFF0160c 0.0031
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.0031
6100 BDNF/NT-3 growth factors receptor NTRK2 0.0031
1852 Microtubule-associated protein 2 MAP2 0.003
6216 High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A PDE8A 0.003
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.003
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.003
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.003
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.003
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.003
1360 Sphingomyelin phosphodiesterase SMPD1 0.003
284 DNA-directed RNA polymerase beta chain rpoB 0.003
5773 DNA-directed RNA polymerase beta chain rpoB 0.003
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.003
691 cAMP-specific 3',5'-cyclic phosphodiesterase 7B PDE7B 0.0029
683 Potassium transporter GK0582 0.0029
1050 Bile salt sulfotransferase SULT2A1 0.0029
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0028
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0028
208 DNA-directed RNA polymerase beta' chain rpoC 0.0028
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0028
1435 Synaptic vesicle glycoprotein 2A SV2A 0.0028
1630 Integrin beta-2 ITGB2 0.0028
1200 AMBP protein AMBP 0.0028
3866 Serum amyloid A protein SAA1 0.0028
1932 Apolipoprotein E APOE 0.0028
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0027
7 Nitric oxide synthase, inducible NOS2 0.0027
6232 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short GNAS 0.0027
6233 Adenylate cyclase type 2 ADCY2 0.0027
6234 Adenylate cyclase type 5 ADCY5 0.0027
1374 Natriuretic peptides B NPPB 0.0027
1827 Gap junction alpha-1 protein GJA1 0.0027
1908 Vascular cell adhesion protein 1 VCAM1 0.0027
2159 Quinone oxidoreductase CRYZ 0.0027
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0027
4773 Deoxycytidine kinase DCK 0.0027
3849 Insulin-like growth factor-binding protein 7 IGFBP7 0.0027
2009 Protein NOV homolog NOV 0.0027
3847 Neuroendocrine convertase 2 PCSK2 0.0027
1949 Carboxypeptidase E CPE 0.0027
3850 Synaptotagmin-like protein 4 SYTL4 0.0027
3848 Neuroendocrine convertase 1 PCSK1 0.0027
3846 Retinoblastoma-associated protein RB1 0.0027
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0027
779 High-affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A PDE7A 0.0026
1864 RET proto-oncogene RET 0.0026
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.0026
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.0026
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.0026
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.0026
6599 HTH-type transcriptional regulator ttgR ttgR 0.0026
790 DNA polymerase subunit alpha B POLA2 0.0026
814 Ryanodine receptor 1 RYR1 0.0026
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0026
5997 Tumor necrosis factor ligand superfamily member 11 TNFSF11 0.0026
85 Growth hormone receptor GHR 0.0025
6859 Protein S100-A4 S100A4 0.0025
1385 Angiotensin-converting enzyme 2 ACE2 0.0025
5880 Thrombopoietin receptor MPL 0.0025
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0025
3830 Calreticulin CALR 0.0025
6020 Aldehyde oxidase AOX1 0.0025
1541 Metalloproteinase mmp20 0.0025
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0025
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0025
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0025
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0025
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0025
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0025
581 Cytochrome P450 2R1 CYP2R1 0.0025
185 Vasopressin V1a receptor AVPR1A 0.0024
936 Ephrin type-A receptor 2 EPHA2 0.0024
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.0024
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0024
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0024
322 Vasopressin V2 receptor AVPR2 0.0024
3639 Thymidine phosphorylase deoA 0.0024
3936 Thymidine phosphorylase TYMP 0.0024
4109 cAMP-specific 3',5'-cyclic phosphodiesterase 4C PDE4C 0.0024
3809 Estrogen-related receptor gamma ESRRG 0.0024
5934 Cytochrome P450 26A1 CYP26A1 0.0024
3611 Cytidine deaminase cdd 0.0024
3707 Cytidine deaminase cdd 0.0024
4211 Cytidine deaminase CDA 0.0024
6070 Nischarin NISCH 0.0024
537 ATP synthase delta chain, mitochondrial ATP5D 0.0024
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0024
6034 Hydroxyindole O-methyltransferase ASMT 0.0023
6035 Nuclear receptor ROR-beta RORB 0.0023
6036 Eosinophil peroxidase EPX 0.0023
1196 Complement decay-accelerating factor CD55 0.0023
4221 Vascular endothelial growth factor VEGF 0.0023
5816 Cadherin-5 CDH5 0.0023
550 Amiloride-sensitive sodium channel subunit delta SCNN1D 0.0023
27 Amiloride-sensitive sodium channel subunit beta SCNN1B 0.0023
552 Amiloride-sensitive sodium channel subunit gamma SCNN1G 0.0023
213 Amiloride-sensitive sodium channel subunit alpha SCNN1A 0.0023
1992 Vitamin D-binding protein GC 0.0023
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0023
6043 Putative G-protein coupled receptor 44 GPR44 0.0023
232 Corticosteroid-binding globulin SERPINA6 0.0023
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0023
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0023
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0023
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0023
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0023
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0023
469 Annexin A1 ANXA1 0.0022
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0022
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0022
707 72 kDa type IV collagenase MMP2 0.0022
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0022
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0022
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0022
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0022
444 Alcohol dehydrogenase 1B ADH1B 0.0022
2155 Insulin-degrading enzyme IDE 0.0022
572 Integrin alpha-L ITGAL 0.0022
908 Glutathione S-transferase theta-1 GSTT1 0.0021
5787 Angiopoietin-1 receptor TEK 0.0021
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0021
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0021
84 Nuclear receptor 0B1 NR0B1 0.0021
4217 Telomerase reverse transcriptase TERT 0.0021
1244 Low-density lipoprotein receptor-related protein 2 LRP2 0.0021
6167 Organic solute transporter subunit beta OSTB 0.0021
6166 Organic solute transporter subunit alpha OSTA 0.0021
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0021
6824 Tyrosine-protein kinase Lyn LYN 0.0021
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0021
63 Malate dehydrogenase mdh 0.0021
2329 Malate dehydrogenase mdh 0.0021
3445 Malate dehydrogenase mdh 0.0021
4420 Malate dehydrogenase mdh 0.0021
4438 Malate dehydrogenase mdh 0.0021
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.002
251 Alcohol dehydrogenase 1A ADH1A 0.002
765 Indoleamine 2,3-dioxygenase IDO1 0.002
4192 DNA topoisomerase 2-beta TOP2B 0.002
144 Hemoglobin subunit alpha HBA1 0.002
3090 Chitosanase csn 0.002
4149 Nuclear factor NF-kappa-B p100 subunit NFKB2 0.002
6160 Solute carrier organic anion transporter family member 3A1 SLCO3A1 0.002
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.002
2808 Chloramphenicol acetyltransferase 3 cat3 0.002
1820 Beta-nerve growth factor NGF 0.002
2107 Microtubule-associated protein 1A MAP1A 0.002
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.002
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0019
2358 cAMP-specific 3',5'-cyclic phosphodiesterase 4D PDE4D 0.0019
820 Glycine receptor subunit alpha-2 GLRA2 0.0019
162 Retinoic acid receptor gamma-1 RARG 0.0019
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0019
512 DNA-directed RNA polymerase alpha chain rpoA 0.0019
5772 DNA-directed RNA polymerase alpha chain rpoA 0.0019
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0019
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0019
3808 Dihydropteroate synthase 2 folP2 0.0019
3601 Dihydropteroate synthase 1 folP1 0.0019
3807 Dihydropteroate synthase 1 folP1 0.0019
2417 Chloramphenicol acetyltransferase cat 0.0018
3278 Chloramphenicol acetyltransferase cat 0.0018
893 [Citrate [pro-3S]-lyase] ligase citC 0.0018
845 Pyruvate dehydrogenase [cytochrome] poxB 0.0018
705 Glutamate receptor 1 GRIA1 0.0018
543 Penicillin-binding protein 1B mrcB 0.0018
6186 Penicillin-binding protein 1B ponB 0.0018
6822 Penicillin-binding protein 1b pbp1b 0.0018
6844 Penicillin-binding protein 1b pbp1b 0.0018
1253 Interferon gamma IFNG 0.0018
2810 Dr hemagglutinin structural subunit draA 0.0018
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.0018
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0018
5626 Nucleoside diphosphate kinase B NME2 0.0018
327 Glutathione reductase gor 0.0018
5110 Glutathione reductase GR2 0.0018
645 Penicillin-binding protein 1A mrcA 0.0018
5805 Penicillin-binding protein 1A ponA 0.0018
6185 Penicillin-binding protein 1A mrcA 0.0018
6799 Penicillin-binding protein 1A pbpA 0.0018
751 Potassium channel subfamily K member 6 KCNK6 0.0018
159 Penicillin-binding protein 2B penA 0.0018
6121 Penicillin-binding protein 2B penA 0.0018
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0018
1714 Mitogen-activated protein kinase 3 MAPK3 0.0018
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0018
3937 Fatty-acid amide hydrolase FAAH 0.0018
517 Alcohol dehydrogenase 1C ADH1C 0.0018
2021 Thrombomodulin THBD 0.0018
268 Adenosine A2b receptor ADORA2B 0.0017
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0017
229 Retinoic acid receptor beta RARB 0.0017
856 Vitamin D3 receptor VDR 0.0017
6048 Troponin C, skeletal muscle TNNC2 0.0017
828 Phenylalanine-4-hydroxylase PAH 0.0017
3109 Phenylalanine-4-hydroxylase phhA 0.0017
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0017
1144 Hepatocyte growth factor receptor MET 0.0017
594 Thyroxine-binding globulin SERPINA7 0.0017
1262 Corticotropin-lipotropin POMC 0.0017
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0017
730 Retinoic acid receptor alpha RARA 0.0017
291 Nitric-oxide synthase, endothelial NOS3 0.0017
3932 Glutathione S-transferase A2 GSTA2 0.0017
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0017
768 FK506-binding protein 1A FKBP1A 0.0017
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0017
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0017
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0017
5798 Mitogen-activated protein kinase 11 MAPK11 0.0017
2320 Thymidine kinase, cytosolic TK1 0.0016
1830 5'-nucleotidase NT5E 0.0016
172 Potassium channel subfamily K member 1 KCNK1 0.0016
633 Penicillin-binding proteins 1A/1B pbpA 0.0016
5923 Microtubule-associated protein tau MAPT 0.0016
5924 Microtubule-associated protein 4 MAP4 0.0016
390 Adenosine A3 receptor ADORA3 0.0016
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0016
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0016
6211 Tubulin epsilon chain TUBE1 0.0016
6212 Tubulin gamma-1 chain TUBG1 0.0016
6210 Tubulin delta chain TUBD1 0.0016
1243 Cathepsin D CTSD 0.0016
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0016
2599 Tyrosine-protein kinase HCK HCK 0.0016
2183 Fatty acid-binding protein, adipocyte FABP4 0.0016
3917 Methylenetetrahydrofolate reductase MTHFR 0.0016
758 Thyroid hormone receptor alpha THRA 0.0016
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0016
2853 14 kDa fatty acid-binding protein Not Available 0.0015
6755 Poliovirus receptor PVR 0.0015
702 UMP-CMP kinase CMPK1 0.0015
982 Cocaine- and amphetamine-regulated transcript protein CARTPT 0.0015
1039 Histone deacetylase 9 HDAC9 0.0015
3844 HLA class II histocompatibility antigen, DQ(6) alpha chain HLA-DQA2 0.0015
6218 Pannexin-1 PANX1 0.0015
5294 Nucleoside diphosphate kinase A NME1 0.0015
1770 Phospholipase C PLCL1 0.0015
2841 Phospholipase C plc 0.0015
1759 85 kDa calcium-independent phospholipase A2 PLA2G6 0.0015
3086 Plasmepsin-2 Not Available 0.0014
760 Fibroblast growth factor 1 FGF1 0.0014
2129 Sucrase-isomaltase, intestinal SI 0.0014
346 Thyroid hormone receptor beta-1 THRB 0.0014
484 Tyrosine-protein kinase ABL2 ABL2 0.0014
4226 Uridine phosphorylase 2 UPP2 0.0014
6169 ATP-binding cassette sub-family A member 5 ABCA5 0.0014
935 Proto-oncogene tyrosine-protein kinase Yes YES1 0.0014
1063 Signal transducer and activator of transcription 5B STAT5B 0.0014
2091 Endoplasmin HSP90B1 0.0014
2232 Interleukin-5 IL5 0.0014
1593 Mucin-2 MUC2 0.0014
6163 Copper-transporting ATPase 2 ATP7B 0.0013
6165 Copper-transporting ATPase 1 ATP7A 0.0013
3404 Exotoxin A eta 0.0013
489 Monocarboxylate transporter 2 SLC16A7 0.0013
6228 Nuclear receptor coactivator 1 NCOA1 0.0013
6241 Nuclear receptor coactivator 2 NCOA2 0.0013
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0013
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0013
4225 Uridine phosphorylase 1 UPP1 0.0013
6042 Prostaglandin reductase 2 PTGR2 0.0013
3426 Glutamine synthetase glnA 0.0013
3987 Glutamine synthetase GLUL 0.0013
860 Nicotinamide N-methyltransferase NNMT 0.0013
699 Nicotinic acid receptor 1 GPR109A 0.0013
928 Nicotinic acid receptor 2 GPR109B 0.0013
583 Nicotinate-nucleotide pyrophosphorylase [carboxylating] QPRT 0.0013
2442 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0013
2459 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0013
6103 Arylamine N-acetyltransferase 1 NAT1 0.0013
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0013
2216 Fibroblast growth factor receptor 4 FGFR4 0.0012
6893 Calcium/calmodulin-dependent protein kinase type II gamma chain CAMK2G 0.0012
3382 Glycolipid transfer protein GLTP 0.0012
694 Matrix protein 2 M 0.0012
934 Proto-oncogene tyrosine-protein kinase Fyn FYN 0.0012
2297 Genome polyprotein Not Available 0.0012
2322 Genome polyprotein Not Available 0.0012
2694 Genome polyprotein Not Available 0.0012
2719 Genome polyprotein Not Available 0.0012
2860 Genome polyprotein Not Available 0.0012
2928 Genome polyprotein Not Available 0.0012
3160 Genome polyprotein Not Available 0.0012
3260 Genome polyprotein Not Available 0.0012
4783 Genome polyprotein Not Available 0.0012
5726 Genome polyprotein Not Available 0.0012
5779 Genome polyprotein Not Available 0.0012
5867 Genome polyprotein Not Available 0.0012
6253 Genome polyprotein Not Available 0.0012
6301 Genome polyprotein Not Available 0.0012
6380 Genome polyprotein Not Available 0.0012
6381 Genome polyprotein Not Available 0.0012
6437 Genome polyprotein Not Available 0.0012
6520 Genome polyprotein Not Available 0.0012
6521 Genome polyprotein Not Available 0.0012
6652 Genome polyprotein Not Available 0.0012
6734 Genome polyprotein Not Available 0.0012
6735 Genome polyprotein Not Available 0.0012
6736 Genome polyprotein Not Available 0.0012
6737 Genome polyprotein Not Available 0.0012
6738 Genome polyprotein Not Available 0.0012
6739 Genome polyprotein Not Available 0.0012
6744 Genome polyprotein Not Available 0.0012
6748 Genome polyprotein Not Available 0.0012
6894 Genome polyprotein Not Available 0.0012
6898 Genome polyprotein Not Available 0.0012
413 Amidophosphoribosyltransferase PPAT 0.0012
2515 Amidophosphoribosyltransferase purF 0.0012
3714 Amidophosphoribosyltransferase purF 0.0012
1792 Tissue-type plasminogen activator PLAT 0.0012
6151 Monocarboxylate transporter 10 SLC16A10 0.0012
461 Glycine receptor subunit alpha-3 GLRA3 0.0012
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0012
695 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A PDE10A 0.0012
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0012
473 L-lactate dehydrogenase A chain LDHA 0.0011
267 Plasminogen activator inhibitor 1 SERPINE1 0.0011
2207 Rhodopsin RHO 0.0011
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0011
1123 Eosinophil cationic protein RNASE3 0.0011
896 Glutathione S-transferase Mu 1 GSTM1 0.0011
6459 Glycodelin PAEP 0.0011
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0011
2290 ADP-ribosyl cyclase 2 BST1 0.001
6033 High affinity interleukin-8 receptor A CXCR1 0.001
6221 Steroid hormone receptor ERR1 ESRRA 0.001
3221 Cytochrome c4 cc4 0.001
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.001
1313 Lactoylglutathione lyase GLO1 0.001
2473 Tyrosine-protein kinase CSK CSK 0.001
2398 Tyrosine-protein kinase ZAP-70 ZAP70 0.001
476 RAC-alpha serine/threonine-protein kinase AKT1 0.001
890 Niemann-Pick C1-like protein 1 NPC1L1 0.001
723 Cytosolic phospholipase A2 PLA2G4A 0.001
199 Monocarboxylate transporter 8 SLC16A2 0.001
3913 Glutamic acid decarboxylase GAD65 0.001
1939 Heat shock protein HSP 90-alpha HSP90AA1 0.001
233 Potassium channel subfamily K member 2 KCNK2 0.0009
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0009
1064 DNA (cytosine-5)-methyltransferase 1 DNMT1 0.0009
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.0009
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0009
1291 cAMP response element-binding protein CREB1 0.0009
1268 Neuropeptide S receptor NPSR1 0.0009
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0009
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0009
1525 Heparin-binding growth factor 2 FGF2 0.0009
1569 G1/S-specific cyclin-D1 CCND1 0.0009
2240 Cell division protein kinase 2 CDK2 0.0009
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0009
4210 Toll-like receptor 4 TLR4 0.0009
1483 Membrane copper amine oxidase AOC3 0.0009
1760 Aminopeptidase N ANPEP 0.0009
6843 Aminopeptidase N pepN 0.0009
6171 Solute carrier family 28 member 3 SLC28A3 0.0009
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0009
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0008
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0008
2236 Casein kinase II subunit alpha CSNK2A1 0.0008
6073 Potassium channel subfamily K member 9 KCNK9 0.0008
6072 Potassium channel subfamily K member 3 KCNK3 0.0008
3616 Fatty acid-binding protein, epidermal FABP5 0.0008
5433 UPF0230 protein TM_1468 TM_1468 0.0008
5430 Hepatocyte nuclear factor 4-gamma HNF4G 0.0008
5431 Lipid binding protein Not Available 0.0008
735 Alanine aminotransferase 1 GPT 0.0008
3904 Alanine aminotransferase 2 GPT2 0.0008
500 Monocarboxylate transporter 4 SLC16A3 0.0008
2530 Protein kinase C theta type PRKCQ 0.0008
400 Coagulation factor IX F9 0.0008
5461 Coagulation factor IX F9 0.0008
866 Large neutral amino acids transporter small subunit 2 SLC7A8 0.0007
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0007
4948 Cytochrome c-553 Not Available 0.0007
4923 Cytochrome c3 DvMF_2499 0.0007
4945 Cytochrome c3 Not Available 0.0007
4949 Cytochrome c3 DVU_3171 0.0007
4968 Cytochrome c3 cytc3 0.0007
4997 Cytochrome c3 SO_2727 0.0007
5219 Cytochrome c3 cyd 0.0007
4902 Nine-heme cytochrome c Ddes_2038 0.0007
3189 High-molecular-weight cytochrome c hmcA 0.0007
822 Aldose reductase AKR1B1 0.0007
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0007
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0007
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0007
6168 Solute carrier family 22 member 16 SLC22A16 0.0007
2038 Inhibitor of nuclear factor kappa-B kinase subunit beta IKBKB 0.0007
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0007
604 Vitamin K-dependent protein Z PROZ 0.0007
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0007
283 SEC14-like protein 2 SEC14L2 0.0007
2408 Tyrosine-protein kinase SYK SYK 0.0007
3587 Gastrotropin FABP6 0.0007
2511 MAP kinase-activated protein kinase 2 MAPKAPK2 0.0007
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.0007
6837 Serine/threonine-protein kinase 17B STK17B 0.0007
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0007
2211 Fatty acid-binding protein, heart FABP3 0.0007
1245 Vitamin K-dependent protein S PROS1 0.0006
422 Vitamin K-dependent protein C PROC 0.0006
6677 Myelin P2 protein PMP2 0.0006
342 P protein [Includes: DNA-directed DNA polymerase P 0.0006
612 P protein [Includes: DNA-directed DNA polymerase P 0.0006
4386 Hemoglobin-like protein HbN glbN 0.0006
1176 Mitogen-activated protein kinase 1 MAPK1 0.0006
677 Choline-phosphate cytidylyltransferase A PCYT1A 0.0006
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0006
719 Retinoic acid receptor responder protein 1 RARRES1 0.0006
770 Retinoic acid-induced protein 3 GPRC5A 0.0006
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0006
5221 Cytochrome c3, 13 kDa Not Available 0.0006
3152 Cytochrome c'' cycA 0.0006
5220 Split-Soret cytochrome c Ddes_2150 0.0006
3700 Cytochrome c-552 precursor nrfA 0.0006
1721 Glycogen synthase kinase-3 beta GSK3B 0.0005
76 Nitric-oxide synthase, brain NOS1 0.0005
3238 Multidrug resistance protein mexA mexA 0.0005
3116 Bacterioferritin bfr 0.0005
4906 Bacterioferritin bfr 0.0005
4965 Bacterioferritin bfr 0.0005
3173 Enolase eno 0.0005
3709 Glycerol uptake facilitator protein glpF 0.0005
3336 C4-dicarboxylate transport transcriptional regulatory protein dctD dctD 0.0005
3393 TGF-beta receptor type-2 TGFBR2 0.0005
5489 Ribonucleoside-diphosphate reductase 1 subunit beta nrdB 0.0005
798 Osteocalcin BGLAP 0.0005
569 Retinal dehydrogenase 2 ALDH1A2 0.0005
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0005
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0005
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0005
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0005
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0005
611 Retinal dehydrogenase 1 ALDH1A1 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
1507 Cytochrome c CYCS 0.0005
2852 DNA mismatch repair protein mutL mutL 0.0005
6133 Sodium channel subunit beta-2 SCN2B 0.0005
6134 Sodium channel subunit beta-3 SCN3B 0.0005
6129 Carbonic anhydrase-related protein 11 CA11 0.0005
6132 Sodium channel subunit beta-1 SCN1B 0.0005
6135 Sodium channel subunit beta-4 SCN4B 0.0005
6127 Carbonic anhydrase-related protein CA8 0.0005
6128 Carbonic anhydrase-related protein 10 CA10 0.0005
6002 Prostaglandin E2 receptor EP4 subtype PTGER4 0.0005
369 Coagulation factor VII F7 0.0005
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0005
3191 Histidinol dehydrogenase hisD 0.0005
4131 Prostaglandin E2 receptor, EP3 subtype PTGER3 0.0004
406 Prostaglandin E2 receptor, EP2 subtype PTGER2 0.0004
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0004
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0004
4692 A/G-specific adenine glycosylase mutY 0.0004
3803 Sodium channel protein type 3 subunit alpha SCN3A 0.0004
6130 Carbonic anhydrase 13 CA13 0.0004
6124 Carbonic anhydrase 5B, mitochondrial CA5B 0.0004
6131 Carbonic anhydrase 14 CA14 0.0004
5818 Folate receptor alpha FOLR1 0.0004
2802 Endoglucanase G celCCG 0.0004
340 Apoptotic protease-activating factor 1 APAF1 0.0004
2391 Ferrochelatase hemH 0.0004
6502 Ferrochelatase DKFZp686P18130 0.0004
1591 Ferrochelatase, mitochondrial FECH 0.0004
6122 Carbonic anhydrase 3 CA3 0.0004
6316 ADP-ribosylation factor 1 ARF1 0.0004
6123 Carbonic anhydrase 5A, mitochondrial CA5A 0.0004
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0003
3007 Carbonic anhydrase 12 CA12 0.0003
4205 Carbonic anhydrase 9 CA9 0.0003
293 Gamma-glutamyl hydrolase GGH 0.0003
825 Arsenical pump-driving ATPase ASNA1 0.0003
3435 Arsenical pump-driving ATPase arsA 0.0003
486 Serine/threonine-protein kinase ALS2CR7 CDK15 0.0003
2105 ATP-binding cassette sub-family G member 1 ABCG1 0.0003
377 Beta-adrenergic receptor kinase 1 ADRBK1 0.0003
510 Serine/threonine-protein kinase receptor R3 ACVRL1 0.0003
733 Activin receptor type 1B ACVR1B 0.0003
225 NEDD8-activating enzyme E1 regulatory subunit NAE1 0.0003
745 Anti-Muellerian hormone type-2 receptor AMHR2 0.0003
483 A-Raf proto-oncogene serine/threonine-protein kinase ARAF 0.0003
21 Beta-adrenergic receptor kinase 2 ADRBK2 0.0003
154 AFG3-like protein 2 AFG3L2 0.0003
395 ALK tyrosine kinase receptor Not Available 0.0003
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0003
6496 Cytochrome c oxidase subunit 8A, mitochondrial COX8A 0.0003
6493 Cytochrome c oxidase subunit 6C COX6C 0.0003
6495 Cytochrome c oxidase subunit 7C, mitochondrial COX7C 0.0003
6499 Cytochrome c oxidase polypeptide 7A1, mitochondrial COX7A1 0.0003
6494 Cytochrome c oxidase subunit 7B, mitochondrial COX7B 0.0003
6491 Cytochrome c oxidase subunit 5A, mitochondrial COX5A 0.0003
6498 Cytochrome c oxidase subunit 6B1 COX6B1 0.0003
6497 Cytochrome c oxidase subunit 6A2, mitochondrial COX6A2 0.0003
6489 Cytochrome c oxidase subunit 4 isoform 1, mitochondrial COX4I1 0.0003
5793 Cytochrome c oxidase subunit 2 MT-CO2 0.0003
6559 Cytochrome c oxidase subunit 2 ctaC 0.0003
6669 Cytochrome c oxidase subunit 2 ctaC 0.0003
6490 Cytochrome c oxidase subunit 3 MT-CO3 0.0003
371 Cytochrome c oxidase subunit 1 MT-CO1 0.0003
6558 Cytochrome c oxidase subunit 1 ctaD 0.0003
292 Activin receptor type-1 ACVR1 0.0003
849 Activated CDC42 kinase 1 TNK2 0.0003
1650 Heme carrier protein 1 SLC46A1 0.0003
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0003
2540 Choloylglycine hydrolase cbh 0.0003
704 Long-chain-fatty-acid--CoA ligase 1 ACSL1 0.0003
821 Acetyl-coenzyme A synthetase 2-like, mitochondrial ACSS1 0.0003
386 Acetyl-coenzyme A synthetase, cytoplasmic ACSS2 0.0003
297 Adenylate cyclase type 1 ADCY1 0.0003
289 Cytosolic purine 5'-nucleotidase NT5C2 0.0003
6501 Fatty acid-binding protein, liver FABP1 0.0003
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0003
740 Argininosuccinate synthase ASS1 0.0002
865 Argininosuccinate synthase ASS1 0.0002
2680 Argininosuccinate synthase argG 0.0002
3194 Argininosuccinate synthase argG 0.0002
661 ADP/ATP translocase 1 SLC25A4 0.0002
6021 Adenosine kinase ADK 0.0002
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0002
6500 Phospholipase A2 PLA2G1B 0.0002
4954 Soluble cytochrome b558 Not Available 0.0002
4916 Cyanoglobin glbN 0.0002
4934 Cytochrome c-551 nirM 0.0002
5218 Cytochrome c-551 nirM 0.0002
4947 Bacterial hemoglobin vhb 0.0002
4915 Cytochrome c-550 psbV 0.0002
4959 Cytochrome c-550 psbV 0.0002
5216 Cytochrome c-550 psbV 0.0002
4925 Cytochrome c-type protein SHP shp 0.0002
4998 Hemoglobin-like protein yjbI yjbI 0.0002
4905 Cytochrome c2 Not Available 0.0002
4939 Cytochrome c2 cycA 0.0002
4964 Cytochrome c2 cycA 0.0002
4979 Cytochrome c2 cycA 0.0002
6673 Cytochrome c2 cycA 0.0002
5000 HemO hemO 0.0002
4975 Cytochrome c-556 RPA3973 0.0002
4984 Neuroglobin NGB 0.0002
4943 Cytochrome c6 petJ 0.0002
4910 Cytoglobin CYGB 0.0002
4907 Cytochrome c-L moxG 0.0002
6865 Cytochrome c-L moxG 0.0002
4981 Iron-starvation protein PigA pigA 0.0002
4971 Nonaheme cytochrome c hmcA 0.0002
4936 Cytochrome c2 iso-2 Not Available 0.0002
4909 CooA protein cooA 0.0002
4994 Hemoglobin-like protein HbO glbO 0.0002
4935 Cytochrome c-554 cycA1 0.0002
644 Heme oxygenase 2 HMOX2 0.0002
4982 Heme oxygenase 2 pbsA2 0.0002
4942 Diheme cytochrome c napB napB 0.0002
4922 Cytochrome c, putative SO_4144 0.0002
4764 Cytochrome P450 165C4 CYP165C4 0.0002
4937 Cytochrome oxidase subunit II rcoxA 0.0002
4989 Cytochrome c551 peroxidase ccp 0.0002
5222 Cytochrome c551 peroxidase ccpA 0.0002
4961 Hemophore HasA hasA 0.0002
4976 Apocytochrome f petA 0.0002
6407 Apocytochrome f petA 0.0002
4904 Cytochrome c family protein GSU1996 0.0002
4903 Methyl-accepting chemotaxis protein Tar4 0.0002
4999 Cytochrome P450 165B3 CYP165B3 0.0002
4960 Putative cytochrome P450-family protein SCO7417 0.0002
4931 Cytochrome P450 167A1 CYP167A1 0.0002
4926 Heme-based aerotactic transducer hemAT hemAT 0.0002
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0002
4993 Hydroxylamine oxidoreductase hao1 0.0002
4972 P450cin cinA 0.0002
3093 Catalase HPII katE 0.0002
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0002
4952 Catalase/peroxidase katA 0.0002
4920 Peroxidase/catalase katG 0.0001
2119 Cytochrome b5 CYB5A 0.0001
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0001
4990 PpcA ppcA 0.0001
4988 Sulfite oxidase, mitochondrial SUOX 0.0001
3375 Acidic cytochrome c3 Not Available 0.0001
2915 Sensor protein fixL fixL 0.0001
4944 Sensor protein fixL fixL 0.0001
4037 Hypothetical protein GPX1 0.0001
4297 Hypothetical protein SP_1951 0.0001
4521 Hypothetical protein BC_2969 0.0001
4540 Hypothetical protein TM_1070 0.0001
4555 Hypothetical protein MT1739 0.0001
4569 Hypothetical protein mshD 0.0001
4578 Hypothetical protein PA3270 0.0001
4747 Hypothetical protein PA3967 0.0001
5177 Hypothetical protein TM_0096 0.0001
5194 Hypothetical protein PA1204 0.0001
5240 Hypothetical protein Rv2991 0.0001
5370 Hypothetical protein TM_1158 0.0001
5710 Hypothetical protein Tb927.5.1360 0.0001
3570 Cytochrome P450 152A1 cypC 0.0001
4385 Cytochrome c' Not Available 0.0001
4967 Cytochrome c' cycA 0.0001
5038 Cytochrome c' Not Available 0.0001
5223 Cytochrome c' cycP 0.0001
4813 Heme oxygenase hmuO 0.0001
5769 Heme oxygenase Not Available 0.0001
4992 Cytochrome c peroxidase Not Available 0.0001
4289 Cytochrome P450 TT_P0059 0.0001
6262 Cytochrome P450 staP 0.0001
2230 Catalase CAT 0.0001
3249 Catalase katA 0.0001
3625 Catalase katA 0.0001
4539 Catalase katA 0.0001
4941 Catalase katB 0.0001
3670 Soluble cytochrome b562 precursor cybC 0.0001
3411 Cytochrome P450 121 cyp121 0.0001
3291 Cytochrome c-552 cycA 0.0001
4927 Cytochrome c-552 nrfA 0.0001
4938 Cytochrome c-552 cycA 0.0001
4953 Cytochrome c-552 nrfA 0.0001
5217 Cytochrome c-552 cycM 0.0001
2617 Nitric oxide synthase oxygenase nos 0.0001
2701 Nitric oxide synthase oxygenase nos 0.0001
3102 Flavohemoprotein hmp 0.0001
4969 Flavohemoprotein hmp 0.0001
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0001
2972 6-deoxyerythronolide B hydroxylase eryF 0.0001
4608 Putative cytochrome P450 SCO1207 0.0001
4963 Putative cytochrome P450 SCO2884 0.0001
6254 Putative cytochrome P450 SCO6998 0.0001
358 Cystathionine beta-synthase CBS 0.0001
693 Hemoglobin subunit beta HBB 0.0001
6268 Hydroxyacid oxidase 1 HAO1 0.0001
810 Heme oxygenase 1 HMOX1 0.0001
3391 Heme oxygenase 1 pbsA1 0.0001
2298 Cytochrome P450-cam camC 0.0001
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