DT-Web

DB06729 - Sulfaphenazole


Identification
Name Sulfaphenazole
Accession Number DB06729
Type small molecule
Description Sulfaphenazole is a sulfonamide antibacterial.
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 314.362
Groups approved
Monoisotopic Weight 314.083746402
Pharmacology
Indication For the treatment bacterial infections.
Mechanism of action Sulfaphenazole is a sulfonamide antibacterial. In bacteria, antibacterial sulfonamides act as competitive inhibitors of the enzyme dihydropteroate synthetase (DHPS), an enzyme involved in folate synthesis. As such, the microorganism will be "starved" of folate and die.
Absorption Not Available
Protein binding Not Available
Biotransformation Hepatic.
Route of elimination Not Available
Toxicity Not Available
Affected organisms
  • Gram negative and gram positive bacteria
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Dihydropteroate synthase
Name Dihydropteroate synthase
Gene Name folP
Pharmacological action yes
Actions inhibitor
References
  • Hong YL, Hossler PA, Calhoun DH, Meshnick SR: Inhibition of recombinant Pneumocystis carinii dihydropteroate synthetase by sulfa drugs. Antimicrob Agents Chemother. 1995 Aug;39(8):1756-63. - Pubmed
DTHybrid score 0.8378

Enzymes


Cytochrome P450 2C9
Name Cytochrome P450 2C9
Gene Name CYP2C9
Actions inhibitor
References
  • Flockhart DA. - Drug Interactions: Cytochrome P450 Drug Interaction Table
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.4841
Cytochrome P450 2A6
Name Cytochrome P450 2A6
Gene Name CYP2A6
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3084
Cytochrome P450 2B6
Name Cytochrome P450 2B6
Gene Name CYP2B6
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3
Cytochrome P450 2C8
Name Cytochrome P450 2C8
Gene Name CYP2C8
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.3142
Cytochrome P450 2D6
Name Cytochrome P450 2D6
Gene Name CYP2D6
Actions inhibitor
References
  • Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions. Nucleic Acids Res. 2010 Jan;38(Database issue):D237-43. Epub 2009 Nov 24. - Pubmed
DTHybrid score 0.41

Predictions


Id Partner name Gene Name Score
5359 Dihydropteroate synthase folP 0.8378
7175 Dihydropteroate synthase sulI 0.8378
4512 Cytochrome P450 3A4 CYP3A4 0.3443
6016 Cytochrome P450 2C19 CYP2C19 0.2535
4200 Cytochrome P450 1A2 CYP1A2 0.1969
587 Serum albumin ALB 0.1678
1588 Multidrug resistance protein 1 ABCB1 0.1538
6013 Cytochrome P450 2E1 CYP2E1 0.1481
4118 Cytochrome P450 3A5 CYP3A5 0.1274
6107 Cytochrome P450 3A7 CYP3A7 0.0984
6024 Cytochrome P450 1A1 CYP1A1 0.0905
20 Prostaglandin G/H synthase 1 PTGS1 0.0869
6106 Cytochrome P450 2C18 CYP2C18 0.0594
492 Histamine H1 receptor HRH1 0.0555
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0517
824 Sodium-dependent serotonin transporter SLC6A4 0.0467
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0404
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0388
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0381
6018 UDP-glucuronosyltransferase 1-9 UGT1A9 0.0379
220 Sodium channel protein type 5 subunit alpha SCN5A 0.0361
1181 Alpha-1-acid glycoprotein 1 ORM1 0.036
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0356
3811 Cytochrome P450 19A1 CYP19A1 0.035
290 Prostaglandin G/H synthase 2 PTGS2 0.035
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0349
502 5-hydroxytryptamine 2A receptor HTR2A 0.0339
831 D(2) dopamine receptor DRD2 0.0318
713 Sodium-dependent dopamine transporter SLC6A3 0.0307
103 Muscarinic acetylcholine receptor M1 CHRM1 0.0307
766 Beta-2 adrenergic receptor ADRB2 0.0304
1729 Solute carrier family 22 member 6 SLC22A6 0.0303
862 Multidrug resistance-associated protein 1 ABCC1 0.03
872 Gamma-aminobutyric-acid receptor subunit alpha-1 GABRA1 0.0293
6102 Arylamine N-acetyltransferase 2 NAT2 0.0287
1898 Cytochrome P450 1B1 CYP1B1 0.0282
6103 Arylamine N-acetyltransferase 1 NAT1 0.0278
556 Alpha-1A adrenergic receptor ADRA1A 0.0277
6178 UDP-glucuronosyltransferase 2B7 UGT2B7 0.0269
6176 UDP-glucuronosyltransferase 1-3 UGT1A3 0.0266
51 Muscarinic acetylcholine receptor M3 CHRM3 0.0259
118 Organic cation/carnitine transporter 2 SLC22A5 0.0253
6145 Solute carrier family 22 member 1 SLC22A1 0.0249
590 5-hydroxytryptamine 2C receptor HTR2C 0.0247
847 Mu-type opioid receptor OPRM1 0.0246
6144 Solute carrier family 22 member 2 SLC22A2 0.0245
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0239
136 Estrogen receptor ESR1 0.0226
617 Muscarinic acetylcholine receptor M2 CHRM2 0.0226
776 Bile salt export pump ABCB11 0.0225
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0221
6017 Cholesterol side-chain cleavage enzyme, mitochondrial CYP11A1 0.0219
465 Calmodulin CALM1 0.0219
341 5-hydroxytryptamine 3 receptor HTR3A 0.0217
468 Cytochrome P450 4A11 CYP4A11 0.0214
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0213
696 Kappa-type opioid receptor OPRK1 0.0212
467 Delta-type opioid receptor OPRD1 0.0209
3941 Amine oxidase [flavin-containing] A MAOA 0.0209
2164 Multidrug resistance-associated protein 4 ABCC4 0.0206
137 FolC bifunctional protein [Includes: Folylpolyglutamate synthase folC 0.0203
193 Beta-1 adrenergic receptor ADRB1 0.0195
318 Alpha-2A adrenergic receptor ADRA2A 0.0187
805 Cytochrome P450 11B1, mitochondrial CYP11B1 0.0186
274 Muscarinic acetylcholine receptor M5 CHRM5 0.0181
6157 Solute carrier organic anion transporter family member 1B3 SLCO1B3 0.018
731 HIV-1 protease HIV-1 protease 0.0179
1632 Solute carrier organic anion transporter family member 2B1 SLCO2B1 0.0178
580 Gamma-aminobutyric-acid receptor subunit alpha-3 GABRA3 0.0177
450 Muscarinic acetylcholine receptor M4 CHRM4 0.0177
4115 Voltage-dependent L-type calcium channel subunit alpha-1D CACNA1D 0.0177
423 Gamma-aminobutyric-acid receptor subunit alpha-2 GABRA2 0.0177
6142 Solute carrier family 22 member 8 SLC22A8 0.0173
478 Voltage-dependent L-type calcium channel subunit alpha-1C CACNA1C 0.0173
3939 Amine oxidase [flavin-containing] B MAOB 0.0171
6147 Solute carrier family 22 member 3 SLC22A3 0.017
523 Gamma-aminobutyric-acid receptor subunit alpha-5 GABRA5 0.0168
122 P2Y purinoceptor 12 P2RY12 0.0165
320 5-hydroxytryptamine 1A receptor HTR1A 0.0165
632 Alpha-1B adrenergic receptor ADRA1B 0.016
4111 Voltage-dependent L-type calcium channel subunit alpha-1S CACNA1S 0.016
6014 Cytochrome P450 2A13 CYP2A13 0.0159
23 D(1A) dopamine receptor DRD1 0.0158
6031 Cytochrome P450 3A43 CYP3A43 0.0157
6143 Solute carrier family 22 member 7 SLC22A7 0.0156
964 Voltage-dependent T-type calcium channel subunit alpha-1H CACNA1H 0.0153
15 Voltage-dependent T-type calcium channel subunit alpha-1I CACNA1I 0.0148
260 Cytochrome P450 51 ERG11 0.0145
761 Cytochrome P450 51 ERG11 0.0145
3163 Cytochrome P450 51 cyp51 0.0145
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0137
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0137
80 Peroxisome proliferator-activated receptor alpha PPARA 0.0136
535 Voltage-dependent T-type calcium channel subunit alpha-1G CACNA1G 0.0134
4110 Voltage-dependent L-type calcium channel subunit beta-2 CACNB2 0.0132
833 Organic cation/carnitine transporter 1 SLC22A4 0.013
841 Gamma-aminobutyric-acid receptor subunit alpha-6 GABRA6 0.013
6104 Dimethylaniline monooxygenase [N-oxide-forming] 1 FMO1 0.013
530 Gamma-aminobutyric-acid receptor subunit alpha-4 GABRA4 0.013
482 Glycine receptor subunit alpha-1 GLRA1 0.0126
238 Peroxisome proliferator-activated receptor gamma PPARG 0.0126
858 Potassium voltage-gated channel subfamily A member 1 KCNA1 0.0124
6136 Multidrug resistance-associated protein 5 ABCC5 0.0124
146 Androgen receptor AR 0.0119
762 Voltage-dependent calcium channel subunit alpha-2/delta-1 CACNA2D1 0.0117
638 D(3) dopamine receptor DRD3 0.0117
198 Sodium channel protein type 10 subunit alpha SCN10A 0.0117
6182 Cytochrome P450 2J2 CYP2J2 0.0116
241 Calcium-transporting ATPase type 2C member 1 ATP2C1 0.0113
4099 Gamma-aminobutyric-acid receptor subunit beta-3 GABRB3 0.0112
70 Type-1 angiotensin II receptor AGTR1 0.0111
380 Cytochrome P450 17A1 CYP17A1 0.011
94 5-hydroxytryptamine 4 receptor HTR4 0.0109
871 Glucocorticoid receptor NR3C1 0.0108
230 ATP-binding cassette transporter sub-family C member 8 ABCC8 0.0108
462 Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 0.0108
537 ATP synthase delta chain, mitochondrial ATP5D 0.0107
1024 Solute carrier family 22 member 11 SLC22A11 0.0105
174 Sigma 1-type opioid receptor SIGMAR1 0.0105
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0104
504 Mast/stem cell growth factor receptor KIT 0.0103
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0103
131 Synaptic vesicular amine transporter SLC18A2 0.0102
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0102
4120 NADPH--cytochrome P450 reductase POR 0.0101
885 5-hydroxytryptamine 1B receptor HTR1B 0.01
947 Neuronal acetylcholine receptor subunit alpha-4 CHRNA4 0.01
4095 Neuronal acetylcholine receptor subunit alpha-7 CHRNA7 0.01
811 Translocator protein TSPO 0.0098
778 Cysteinyl leukotriene receptor 1 CYSLTR1 0.0097
3804 Sodium channel protein type 4 subunit alpha SCN4A 0.0097
6177 UDP-glucuronosyltransferase 1-10 UGT1A10 0.0096
6181 UDP-glucuronosyltransferase 1-8 UGT1A8 0.0096
3923 Cholinesterase BCHE 0.0094
6101 Dimethylaniline monooxygenase [N-oxide-forming] 3 FMO3 0.0093
869 Estrogen receptor beta ESR2 0.0093
436 5-hydroxytryptamine 2B receptor HTR2B 0.0092
4100 Gamma-aminobutyric-acid receptor subunit beta-2 GABRB2 0.0092
620 Bifunctional dihydrofolate reductase-thymidylate synthase Not Available 0.009
6045 Voltage-dependent calcium channel subunit alpha-2/delta-3 CACNA2D3 0.009
4604 Liver carboxylesterase 1 CES1 0.0089
705 Glutamate receptor 1 GRIA1 0.0089
844 Epidermal growth factor receptor EGFR 0.0089
4116 Dihydropteroate synthetase Not Available 0.0087
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0086
1010 Cytochrome P450 51A1 CYP51A1 0.0086
817 DNA topoisomerase 2-alpha TOP2A 0.0085
365 Dihydrofolate reductase DHFR 0.0085
2381 Dihydrofolate reductase DFR1 0.0085
2833 Dihydrofolate reductase Not Available 0.0085
2931 Dihydrofolate reductase folA 0.0085
3544 Dihydrofolate reductase folA 0.0085
3682 Dihydrofolate reductase folA 0.0085
6642 Dihydrofolate reductase folA 0.0085
6756 Dihydrofolate reductase dfrA 0.0085
6079 Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 0.0085
610 Calcium-activated potassium channel subunit alpha 1 KCNMA1 0.0085
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0084
789 Alpha-1D adrenergic receptor ADRA1D 0.0082
6141 Sodium/bile acid cotransporter SLC10A1 0.0082
725 5-hydroxytryptamine 1D receptor HTR1D 0.008
158 Sodium channel protein type 1 subunit alpha SCN1A 0.0079
629 Alpha-2B adrenergic receptor ADRA2B 0.0079
432 D(4) dopamine receptor DRD4 0.0079
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0078
275 Arachidonate 5-lipoxygenase ALOX5 0.0077
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0077
385 Potassium-transporting ATPase alpha chain 1 ATP4A 0.0077
716 5-hydroxytryptamine 7 receptor HTR7 0.0076
6137 Multidrug resistance-associated protein 6 ABCC6 0.0076
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0075
6220 Aryl hydrocarbon receptor AHR 0.0075
4113 Voltage-dependent L-type calcium channel subunit alpha-1F CACNA1F 0.0074
1539 Oligopeptide transporter, small intestine isoform SLC15A1 0.0073
3810 Catechol O-methyltransferase COMT 0.0073
2183 Fatty acid-binding protein, adipocyte FABP4 0.0072
1457 Long-chain-fatty-acid--CoA ligase 4 ACSL4 0.0072
621 Periplasmic [Fe] hydrogenase 1 Not Available 0.0071
6086 Gamma-aminobutyric acid receptor subunit gamma-2 GABRG2 0.0071
518 Peroxidase/catalase T katG 0.0071
921 Glutamate receptor 2 GRIA2 0.0071
2230 Catalase CAT 0.007
3249 Catalase katA 0.007
3625 Catalase katA 0.007
4539 Catalase katA 0.007
4941 Catalase katB 0.007
5878 Alpha-7 nicotinic cholinergic receptor subunit CHRFAM7A 0.007
3932 Glutathione S-transferase A2 GSTA2 0.007
1656 CYP2B protein CYP2B 0.0069
84 Nuclear receptor 0B1 NR0B1 0.0068
1995 Sodium channel protein type 9 subunit alpha SCN9A 0.0068
1757 Myeloperoxidase MPO 0.0068
6085 Fatty acid-binding protein, intestinal FABP2 0.0067
563 Thyroid peroxidase TPO 0.0067
4177 Proto-oncogene tyrosine-protein kinase receptor ret RET 0.0067
1636 Trace amine-associated receptor 1 TAAR1 0.0067
17 Proto-oncogene tyrosine-protein kinase ABL1 ABL1 0.0067
295 Carbonic anhydrase 1 CA1 0.0066
378 Alpha-2C adrenergic receptor ADRA2C 0.0066
88 Retinoic acid receptor RXR-beta RXRB 0.0064
474 Acetylcholinesterase ACHE 0.0064
407 Vascular endothelial growth factor receptor 2 KDR 0.0064
1192 Sulfotransferase 1A1 SULT1A1 0.0063
133 Dihydropterate synthase sulI 0.0063
251 Alcohol dehydrogenase 1A ADH1A 0.0063
427 Substance-P receptor TACR1 0.0062
982 Cocaine- and amphetamine-regulated transcript protein CARTPT 0.0062
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0062
1275 Estrogen sulfotransferase SULT1E1 0.0061
2112 Toll-like receptor 9 TLR9 0.0061
6088 Gamma-aminobutyric acid receptor subunit gamma-3 GABRG3 0.0061
6090 Gamma-aminobutyric acid receptor subunit pi GABRP 0.0061
6092 Gamma-aminobutyric acid receptor subunit rho-2 GABRR2 0.0061
6115 Gamma-aminobutyric acid receptor subunit rho-3 GABRR3 0.0061
813 Neuronal acetylcholine receptor subunit alpha-2 CHRNA2 0.006
4203 Histamine N-methyltransferase HNMT 0.006
6089 Gamma-aminobutyric acid receptor subunit epsilon GABRE 0.006
6093 Gamma-aminobutyric acid receptor subunit delta GABRD 0.006
6087 Gamma-aminobutyric acid receptor subunit gamma-1 GABRG1 0.006
738 Monocarboxylate transporter 1 SLC16A1 0.006
142 Gamma-aminobutyric-acid receptor subunit rho-1 GABRR1 0.006
1541 Metalloproteinase mmp20 0.006
24 Thymidylate synthase TMP1 0.006
359 Thymidylate synthase TYMS 0.006
2626 Thymidylate synthase thyA 0.006
2729 Thymidylate synthase thyA 0.006
5352 Thymidylate synthase THYA 0.006
4238 50S ribosomal protein L4 rplD 0.0059
5578 50S ribosomal protein L4 rplD 0.0059
6173 50S ribosomal protein L4 rplD 0.0059
6219 50S ribosomal protein L4 rplD 0.0059
124 Histamine H2 receptor HRH2 0.0059
373 Transthyretin TTR 0.0059
6023 Cytochrome P450 11B2, mitochondrial CYP11B2 0.0059
4098 Gamma-aminobutyric-acid receptor subunit beta-1 GABRB1 0.0058
1086 Potassium voltage-gated channel subfamily KQT member 2 KCNQ2 0.0058
161 Tubulin beta chain TUBB 0.0057
312 Tubulin beta chain TUB2 0.0057
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0057
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0057
781 ATP-sensitive inward rectifier potassium channel 11 KCNJ11 0.0056
6174 50S ribosomal protein L32 rpmF 0.0056
6148 Multidrug resistance-associated protein 7 ABCC10 0.0056
444 Alcohol dehydrogenase 1B ADH1B 0.0056
528 5-hydroxytryptamine 1E receptor HTR1E 0.0056
29 Tubulin beta-1 chain TUBB1 0.0056
698 B-Raf proto-oncogene serine/threonine-protein kinase BRAF 0.0056
6158 Solute carrier organic anion transporter family member 1C1 SLCO1C1 0.0056
6091 Gamma-aminobutyric acid receptor subunit theta GABRQ 0.0055
458 Neuronal acetylcholine receptor subunit alpha-10 CHRNA10 0.0055
392 Voltage-dependent P/Q-type calcium channel subunit alpha-1A CACNA1A 0.0055
1050 Bile salt sulfotransferase SULT2A1 0.0055
4237 50S ribosomal protein L22 rplV 0.0054
228 Beta platelet-derived growth factor receptor PDGFRB 0.0054
614 Progesterone receptor PGR 0.0054
756 Sex hormone-binding globulin SHBG 0.0054
40 RAF proto-oncogene serine/threonine-protein kinase RAF1 0.0053
952 Dipeptidyl peptidase 4 DPP4 0.0053
163 D(1B) dopamine receptor DRD5 0.0053
26 Vascular endothelial growth factor receptor 3 FLT4 0.0052
3809 Estrogen-related receptor gamma ESRRG 0.0052
6046 Voltage-gated calcium channel beta 1 subunit splice variant CavB1d CACNB1 0.005
32 Vascular endothelial growth factor receptor 1 FLT1 0.005
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0049
208 DNA-directed RNA polymerase beta' chain rpoC 0.0049
5774 DNA-directed RNA polymerase beta' chain rpoC 0.0049
737 Mineralocorticoid receptor NR3C2 0.0048
517 Alcohol dehydrogenase 1C ADH1C 0.0048
162 Retinoic acid receptor gamma-1 RARG 0.0048
950 Alpha platelet-derived growth factor receptor PDGFRA 0.0048
750 Voltage-dependent calcium channel gamma-1 subunit CACNG1 0.0047
3970 Voltage-dependent N-type calcium channel subunit alpha-1B CACNA1B 0.0047
780 Retinoic acid receptor RXR-gamma RXRG 0.0047
6047 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A PDE1A 0.0046
527 Prostacyclin receptor PTGIR 0.0045
4162 Potassium voltage-gated channel subfamily KQT member 3 KCNQ3 0.0045
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0045
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0045
3678 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0045
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0045
7 Nitric oxide synthase, inducible NOS2 0.0045
3854 Basic fibroblast growth factor receptor 1 FGFR1 0.0045
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0045
6020 Aldehyde oxidase AOX1 0.0044
232 Corticosteroid-binding globulin SERPINA6 0.0044
5692 Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B PDE1B 0.0044
6180 UDP-glucuronosyltransferase 2B4 UGT2B4 0.0044
49 Endothelin B receptor EDNRB 0.0044
6138 Multidrug resistance protein 3 ABCB4 0.0043
777 Tumor necrosis factor TNF 0.0042
606 Cytochrome P450 27, mitochondrial CYP27A1 0.0042
106 Cannabinoid receptor 2 CNR2 0.0042
3947 Xanthine dehydrogenase/oxidase XDH 0.0042
719 Retinoic acid receptor responder protein 1 RARRES1 0.0042
770 Retinoic acid-induced protein 3 GPRC5A 0.0042
4160 Voltage-dependent calcium channel subunit alpha-2/delta-2 CACNA2D2 0.0041
1618 High affinity nerve growth factor receptor NTRK1 0.0041
1629 Transcription factor AP-1 JUN 0.0041
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0041
592 Carbonic anhydrase 4 CA4 0.0041
578 Endothelin-1 receptor EDNRA 0.0041
1178 Adenosine A2a receptor ADORA2A 0.0041
581 Cytochrome P450 2R1 CYP2R1 0.0041
709 ATP-sensitive inward rectifier potassium channel 1 KCNJ1 0.0041
469 Annexin A1 ANXA1 0.0041
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.004
1256 5-hydroxytryptamine 6 receptor HTR6 0.004
990 Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 0.004
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0039
68 Cannabinoid receptor 1 CNR1 0.0039
360 Ribonucleoside-diphosphate reductase large subunit RRM1 0.0039
3639 Thymidine phosphorylase deoA 0.0039
3936 Thymidine phosphorylase TYMP 0.0039
3802 Sodium channel protein type 2 subunit alpha SCN2A 0.0039
1992 Vitamin D-binding protein GC 0.0039
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0038
4209 ATP-sensitive inward rectifier potassium channel 8 KCNJ8 0.0038
1262 Corticotropin-lipotropin POMC 0.0038
4164 Potassium voltage-gated channel subfamily KQT member 5 KCNQ5 0.0038
4163 Potassium voltage-gated channel subfamily KQT member 4 KCNQ4 0.0038
319 Opioid receptor, sigma 1 OPRS1 0.0038
6068 Guanylate cyclase soluble subunit alpha-2 GUCY1A2 0.0038
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0037
1648 Elastin ELN 0.0037
6080 Neuronal acetylcholine receptor subunit alpha-5 CHRNA5 0.0037
6082 Neuronal acetylcholine receptor subunit beta-3 CHRNB3 0.0037
948 Neuronal acetylcholine receptor subunit beta-2 CHRNB2 0.0037
5934 Cytochrome P450 26A1 CYP26A1 0.0037
569 Retinal dehydrogenase 2 ALDH1A2 0.0037
130 Prostacyclin synthase PTGIS 0.0037
823 Fibroblast growth factor receptor 2 FGFR2 0.0036
558 Solute carrier family 12 member 1 SLC12A1 0.0036
3086 Plasmepsin-2 Not Available 0.0036
1630 Integrin beta-2 ITGB2 0.0036
1502 Peroxisome proliferator-activated receptor delta PPARD 0.0036
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0036
4226 Uridine phosphorylase 2 UPP2 0.0035
4217 Telomerase reverse transcriptase TERT 0.0035
611 Retinal dehydrogenase 1 ALDH1A1 0.0035
6081 Neuronal acetylcholine receptor subunit alpha-6 CHRNA6 0.0034
4097 Neuronal acetylcholine receptor subunit alpha-9 CHRNA9 0.0034
3937 Fatty-acid amide hydrolase FAAH 0.0034
2298 Cytochrome P450-cam camC 0.0034
3917 Methylenetetrahydrofolate reductase MTHFR 0.0034
54 Prothrombin F2 0.0034
6126 Carbonic anhydrase 7 CA7 0.0034
1974 Oligopeptide transporter, kidney isoform SLC15A2 0.0034
164 Histamine H4 receptor HRH4 0.0034
6432 Transporter snf 0.0033
6506 Stathmin-4 STMN4 0.0033
564 Cellular retinoic acid-binding protein 1 CRABP1 0.0033
173 Toll-like receptor 7 TLR7 0.0033
5880 Thrombopoietin receptor MPL 0.0033
4225 Uridine phosphorylase 1 UPP1 0.0032
4122 Histone deacetylase 2 HDAC2 0.0032
6146 High affinity copper uptake protein 1 SLC31A1 0.0032
818 50S ribosomal protein L10 rplJ 0.0032
859 Cellular retinoic acid-binding protein 2 CRABP2 0.0032
1768 Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit GNG2 0.0032
16 Adenosine A1 receptor ADORA1 0.0032
1039 Histone deacetylase 9 HDAC9 0.0032
1581 G protein-activated inward rectifier potassium channel 2 KCNJ6 0.0032
1268 Neuropeptide S receptor NPSR1 0.0032
1571 G protein-activated inward rectifier potassium channel 1 KCNJ3 0.0032
165 FL cytokine receptor FLT3 0.0032
6931 Calcium-activated potassium channel subunit beta-1 KCNMB1 0.0032
6933 Calcium-activated potassium channel subunit beta-4 KCNMB4 0.0032
6932 Calcium-activated potassium channel subunit beta-3 KCNMB3 0.0032
6934 Small conductance calcium-activated potassium channel protein 1 KCNN1 0.0032
6935 Small conductance calcium-activated potassium channel protein 2 KCNN2 0.0032
6936 Small conductance calcium-activated potassium channel protein 3 KCNN3 0.0032
6078 Neuronal acetylcholine receptor subunit beta-4 CHRNB4 0.0032
634 Squalene monooxygenase SQLE 0.0031
7196 Squalene monooxygenase ERG1 0.0031
511 5-hydroxytryptamine 1F receptor HTR1F 0.0031
514 Potassium voltage-gated channel subfamily H member 6 KCNH6 0.0031
772 Potassium voltage-gated channel subfamily H member 7 KCNH7 0.0031
1227 Cytochrome b MT-CYB 0.0031
6386 Cytochrome b petB 0.0031
6937 Cytochrome b MT-CYB 0.0031
674 Dihydroorotate dehydrogenase homolog, mitochondrial PFF0160c 0.0031
4199 Sphingosine 1-phosphate receptor Edg-8 S1PR5 0.0031
357 Carbonic anhydrase 2 CA2 0.0031
413 Amidophosphoribosyltransferase PPAT 0.003
2515 Amidophosphoribosyltransferase purF 0.003
3714 Amidophosphoribosyltransferase purF 0.003
3856 Fibroblast growth factor receptor 3 FGFR3 0.003
2207 Rhodopsin RHO 0.0029
515 26S proteasome non-ATPase regulatory subunit 1 PSMD1 0.0029
522 26S proteasome non-ATPase regulatory subunit 2 PSMD2 0.0029
183 Vascular endothelial growth factor A VEGFA 0.0029
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0029
6073 Potassium channel subfamily K member 9 KCNK9 0.0029
6072 Potassium channel subfamily K member 3 KCNK3 0.0029
856 Vitamin D3 receptor VDR 0.0029
424 Dihydroorotate dehydrogenase, mitochondrial DHODH 0.0029
2180 3-phosphoinositide-dependent protein kinase 1 PDPK1 0.0028
565 Extracellular calcium-sensing receptor CASR 0.0028
5463 Calcium-activated potassium channel subunit beta 2 KCNMB2 0.0028
5787 Angiopoietin-1 receptor TEK 0.0028
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0028
630 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial ACADSB 0.0028
6152 Solute carrier organic anion transporter family member 2A1 SLCO2A1 0.0028
1200 AMBP protein AMBP 0.0028
3866 Serum amyloid A protein SAA1 0.0028
1932 Apolipoprotein E APOE 0.0028
2320 Thymidine kinase, cytosolic TK1 0.0027
6206 DNA-directed RNA polymerase subunit beta' rpoC 0.0027
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0027
2159 Quinone oxidoreductase CRYZ 0.0027
541 cAMP-specific 3',5'-cyclic phosphodiesterase 4B PDE4B 0.0027
6040 6-phosphogluconate dehydrogenase, decarboxylating PGD 0.0026
571 Melatonin receptor type 1A MTNR1A 0.0026
362 Melatonin receptor type 1B MTNR1B 0.0026
2981 Phospholipase A2, membrane associated PLA2G2A 0.0026
4311 tRNA TRDMT1 0.0026
4325 tRNA trmD 0.0026
4328 tRNA trmD 0.0026
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0025
284 DNA-directed RNA polymerase beta chain rpoB 0.0025
5773 DNA-directed RNA polymerase beta chain rpoB 0.0025
1196 Complement decay-accelerating factor CD55 0.0025
6033 High affinity interleukin-8 receptor A CXCR1 0.0025
6099 Potassium voltage-gated channel subfamily D member 3 KCND3 0.0025
6098 Potassium voltage-gated channel subfamily D member 2 KCND2 0.0025
239 Coagulation factor X F10 0.0025
1360 Sphingomyelin phosphodiesterase SMPD1 0.0025
291 Nitric-oxide synthase, endothelial NOS3 0.0024
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0024
485 cGMP-inhibited 3',5'-cyclic phosphodiesterase A PDE3A 0.0024
153 Dopamine beta-hydroxylase DBH 0.0024
5300 Antigen peptide transporter 1 TAP1 0.0024
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0024
215 Sodium channel protein type 11 subunit alpha SCN11A 0.0024
229 Retinoic acid receptor beta RARB 0.0024
1787 Nuclear factor NF-kappa-B p105 subunit NFKB1 0.0024
751 Potassium channel subfamily K member 6 KCNK6 0.0023
730 Retinoic acid receptor alpha RARA 0.0023
459 Retinoic acid receptor RXR-alpha RXRA 0.0023
976 Platelet glycoprotein IX GP9 0.0023
4103 Proteasome subunit beta type 2 PSMB2 0.0023
4102 Proteasome subunit beta type 5 PSMB5 0.0023
4101 Proteasome subunit beta type 1 PSMB1 0.0023
5798 Mitogen-activated protein kinase 11 MAPK11 0.0023
267 Plasminogen activator inhibitor 1 SERPINE1 0.0022
2808 Chloramphenicol acetyltransferase 3 cat3 0.0022
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0022
814 Ryanodine receptor 1 RYR1 0.0022
172 Potassium channel subfamily K member 1 KCNK1 0.0022
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0021
567 Receptor tyrosine-protein kinase erbB-2 ERBB2 0.0021
4114 Voltage-dependent L-type calcium channel subunit beta-3 CACNB3 0.0021
4112 Voltage-dependent L-type calcium channel subunit beta-4 CACNB4 0.0021
63 Malate dehydrogenase mdh 0.0021
2329 Malate dehydrogenase mdh 0.0021
3445 Malate dehydrogenase mdh 0.0021
4420 Malate dehydrogenase mdh 0.0021
4438 Malate dehydrogenase mdh 0.0021
273 Apoptosis regulator Bcl-2 BCL2 0.002
3808 Dihydropteroate synthase 2 folP2 0.002
3601 Dihydropteroate synthase 1 folP1 0.002
3807 Dihydropteroate synthase 1 folP1 0.002
2417 Chloramphenicol acetyltransferase cat 0.002
3278 Chloramphenicol acetyltransferase cat 0.002
6221 Steroid hormone receptor ERR1 ESRRA 0.002
400 Coagulation factor IX F9 0.002
5461 Coagulation factor IX F9 0.002
6048 Troponin C, skeletal muscle TNNC2 0.002
2810 Dr hemagglutinin structural subunit draA 0.002
6100 BDNF/NT-3 growth factors receptor NTRK2 0.002
2718 Chloramphenicol 3-O phosphotransferase Not Available 0.002
6179 UDP-glucuronosyltransferase 2B17 UGT2B17 0.002
477 DNA topoisomerase 4 subunit A parC 0.002
886 DNA topoisomerase 4 subunit A parC 0.002
6226 DNA topoisomerase 4 subunit A parC 0.002
6153 Solute carrier organic anion transporter family member 4A1 SLCO4A1 0.0019
404 DNA gyrase subunit A gyrA 0.0019
6224 DNA gyrase subunit A gyrA 0.0019
268 Adenosine A2b receptor ADORA2B 0.0019
333 Voltage-dependent L-type calcium channel subunit beta-1 CACNB1 0.0019
6044 Serum paraoxonase/lactonase 3 PON3 0.0019
904 Glutathione S-transferase P GSTP1 0.0018
893 [Citrate [pro-3S]-lyase] ligase citC 0.0018
845 Pyruvate dehydrogenase [cytochrome] poxB 0.0018
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0018
604 Vitamin K-dependent protein Z PROZ 0.0018
327 Glutathione reductase gor 0.0018
5110 Glutathione reductase GR2 0.0018
748 5'-AMP-activated protein kinase catalytic subunit alpha-1 PRKAA1 0.0018
1341 Histamine H3 receptor HRH3 0.0018
572 Integrin alpha-L ITGAL 0.0017
936 Ephrin type-A receptor 2 EPHA2 0.0017
6154 Multidrug and toxin extrusion protein 1 SLC47A1 0.0017
3868 Calcineurin subunit B isoform 2 PPP3R2 0.0017
421 Calcium signal-modulating cyclophilin ligand CAMLG 0.0017
1144 Hepatocyte growth factor receptor MET 0.0017
908 Glutathione S-transferase theta-1 GSTT1 0.0017
594 Thyroxine-binding globulin SERPINA7 0.0017
992 Protein tyrosine kinase 2 beta PTK2B 0.0017
820 Glycine receptor subunit alpha-2 GLRA2 0.0017
6149 Solute carrier family 22 member 10 SLC22A10 0.0017
1245 Vitamin K-dependent protein S PROS1 0.0017
422 Vitamin K-dependent protein C PROC 0.0017
4228 Keratin, type II cytoskeletal 7 KRT7 0.0016
389 Amiloride-sensitive cation channel 2, neuronal ACCN2 0.0016
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0016
2450 Tyrosine-protein kinase ITK/TSK ITK 0.0015
2216 Fibroblast growth factor receptor 4 FGFR4 0.0015
758 Thyroid hormone receptor alpha THRA 0.0015
2853 14 kDa fatty acid-binding protein Not Available 0.0015
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0015
1517 Beta-3 adrenergic receptor ADRB3 0.0015
6038 Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6H 0.0015
3611 Cytidine deaminase cdd 0.0014
3707 Cytidine deaminase cdd 0.0014
4211 Cytidine deaminase CDA 0.0014
199 Monocarboxylate transporter 8 SLC16A2 0.0014
4773 Deoxycytidine kinase DCK 0.0014
245 Large neutral amino acids transporter small subunit 1 SLC7A5 0.0014
2539 Tubulin alpha-1 chain TUBA4A 0.0014
4148 Serine/threonine-protein kinase mTOR MTOR 0.0014
6037 Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma PDE6G 0.0014
798 Osteocalcin BGLAP 0.0014
346 Thyroid hormone receptor beta-1 THRB 0.0014
2232 Interleukin-5 IL5 0.0014
1291 cAMP response element-binding protein CREB1 0.0014
1593 Mucin-2 MUC2 0.0014
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.0013
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.0013
1971 cAMP-specific 3',5'-cyclic phosphodiesterase 4A PDE4A 0.0013
2021 Thrombomodulin THBD 0.0013
6150 Solute carrier organic anion transporter family member 4C1 SLCO4C1 0.0013
3404 Exotoxin A eta 0.0013
1374 Natriuretic peptides B NPPB 0.0013
1827 Gap junction alpha-1 protein GJA1 0.0013
1908 Vascular cell adhesion protein 1 VCAM1 0.0013
2184 Cystic fibrosis transmembrane conductance regulator CFTR 0.0013
4210 Toll-like receptor 4 TLR4 0.0013
73 Prostaglandin E2 receptor, EP1 subtype PTGER1 0.0013
489 Monocarboxylate transporter 2 SLC16A7 0.0013
3957 Adenosine deaminase ADA 0.0013
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0013
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0013
860 Nicotinamide N-methyltransferase NNMT 0.0013
699 Nicotinic acid receptor 1 GPR109A 0.0013
928 Nicotinic acid receptor 2 GPR109B 0.0013
583 Nicotinate-nucleotide pyrophosphorylase [carboxylating] QPRT 0.0013
2442 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0013
2459 Nicotinate-nucleotide pyrophosphorylase [carboxylating] nadC 0.0013
5923 Microtubule-associated protein tau MAPT 0.0013
5924 Microtubule-associated protein 4 MAP4 0.0013
369 Coagulation factor VII F7 0.0012
6140 Ileal sodium/bile acid cotransporter SLC10A2 0.0012
5433 UPF0230 protein TM_1468 TM_1468 0.0012
5431 Lipid binding protein Not Available 0.0012
3616 Fatty acid-binding protein, epidermal FABP5 0.0012
5430 Hepatocyte nuclear factor 4-gamma HNF4G 0.0012
102 DNA topoisomerase I, mitochondrial TOP1MT 0.0012
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0012
1852 Microtubule-associated protein 2 MAP2 0.0012
6163 Copper-transporting ATPase 2 ATP7B 0.0012
6165 Copper-transporting ATPase 1 ATP7A 0.0012
6824 Tyrosine-protein kinase Lyn LYN 0.0012
473 L-lactate dehydrogenase A chain LDHA 0.0011
6164 POU domain, class 5, transcription factor 1 POU5F1 0.0011
4948 Cytochrome c-553 Not Available 0.0011
4923 Cytochrome c3 DvMF_2499 0.0011
4945 Cytochrome c3 Not Available 0.0011
4949 Cytochrome c3 DVU_3171 0.0011
4968 Cytochrome c3 cytc3 0.0011
4997 Cytochrome c3 SO_2727 0.0011
5219 Cytochrome c3 cyd 0.0011
4902 Nine-heme cytochrome c Ddes_2038 0.0011
3189 High-molecular-weight cytochrome c hmcA 0.0011
6218 Pannexin-1 PANX1 0.0011
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0011
760 Fibroblast growth factor 1 FGF1 0.0011
1123 Eosinophil cationic protein RNASE3 0.0011
3913 Glutamic acid decarboxylase GAD65 0.0011
707 72 kDa type IV collagenase MMP2 0.0011
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0011
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0011
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0011
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0011
6168 Solute carrier family 22 member 16 SLC22A16 0.0011
6155 ATP-binding cassette transporter sub-family C member 11 ABCC11 0.0011
2290 ADP-ribosyl cyclase 2 BST1 0.001
2300 Lysozyme E 0.001
3633 Lysozyme R 0.001
5597 Lysozyme 17 0.001
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.001
1483 Membrane copper amine oxidase AOC3 0.001
283 SEC14-like protein 2 SEC14L2 0.001
144 Hemoglobin subunit alpha HBA1 0.001
6151 Monocarboxylate transporter 10 SLC16A10 0.001
76 Nitric-oxide synthase, brain NOS1 0.001
1864 RET proto-oncogene RET 0.001
6837 Serine/threonine-protein kinase 17B STK17B 0.001
6836 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial HIBCH 0.001
1353 DNA topoisomerase 1 TOP1 0.001
3552 DNA topoisomerase 1 topA 0.001
1950 Epithelial discoidin domain-containing receptor 1 DDR1 0.001
6170 ATP-binding cassette sub-family A member 3 ABCA3 0.001
6094 BCR/ABL fusion protein isoform X9 BCR/ABL fusion 0.001
4386 Hemoglobin-like protein HbN glbN 0.001
896 Glutathione S-transferase Mu 1 GSTM1 0.001
5432 Trafficking protein particle complex subunit 3 TRAPPC3 0.0009
2211 Fatty acid-binding protein, heart FABP3 0.0009
6459 Glycodelin PAEP 0.0009
3126 Poly [ADP-ribose] polymerase 1 PARP1 0.0009
1064 DNA (cytosine-5)-methyltransferase 1 DNMT1 0.0009
735 Alanine aminotransferase 1 GPT 0.0009
3904 Alanine aminotransferase 2 GPT2 0.0009
65 Matrix metalloproteinase-9 Not Available 0.0009
1792 Tissue-type plasminogen activator PLAT 0.0009
741 Potassium voltage-gated channel subfamily KQT member 1 KCNQ1 0.0009
6677 Myelin P2 protein PMP2 0.0009
3221 Cytochrome c4 cc4 0.0009
937 Proto-oncogene tyrosine-protein kinase LCK LCK 0.0009
6656 UDP-glucuronosyltransferase 3A1 UGT3A1 0.0008
244 Angiotensin-converting enzyme ACE 0.0008
6212 Tubulin gamma-1 chain TUBG1 0.0008
6210 Tubulin delta chain TUBD1 0.0008
6211 Tubulin epsilon chain TUBE1 0.0008
6599 HTH-type transcriptional regulator ttgR ttgR 0.0008
500 Monocarboxylate transporter 4 SLC16A3 0.0008
951 Macrophage colony-stimulating factor 1 receptor CSF1R 0.0008
276 Sodium- and chloride-dependent GABA transporter 1 SLC6A1 0.0008
3830 Calreticulin CALR 0.0008
1507 Cytochrome c CYCS 0.0007
866 Large neutral amino acids transporter small subunit 2 SLC7A8 0.0007
2599 Tyrosine-protein kinase HCK HCK 0.0007
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0007
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0007
4954 Soluble cytochrome b558 Not Available 0.0007
4925 Cytochrome c-type protein SHP shp 0.0007
4916 Cyanoglobin glbN 0.0007
4947 Bacterial hemoglobin vhb 0.0007
4915 Cytochrome c-550 psbV 0.0007
4959 Cytochrome c-550 psbV 0.0007
5216 Cytochrome c-550 psbV 0.0007
4934 Cytochrome c-551 nirM 0.0007
5218 Cytochrome c-551 nirM 0.0007
4975 Cytochrome c-556 RPA3973 0.0007
4943 Cytochrome c6 petJ 0.0007
4994 Hemoglobin-like protein HbO glbO 0.0007
4905 Cytochrome c2 Not Available 0.0007
4939 Cytochrome c2 cycA 0.0007
4964 Cytochrome c2 cycA 0.0007
4979 Cytochrome c2 cycA 0.0007
6673 Cytochrome c2 cycA 0.0007
4936 Cytochrome c2 iso-2 Not Available 0.0007
4984 Neuroglobin NGB 0.0007
4998 Hemoglobin-like protein yjbI yjbI 0.0007
5000 HemO hemO 0.0007
3116 Bacterioferritin bfr 0.0007
4906 Bacterioferritin bfr 0.0007
4965 Bacterioferritin bfr 0.0007
4909 CooA protein cooA 0.0007
4910 Cytoglobin CYGB 0.0007
4907 Cytochrome c-L moxG 0.0007
6865 Cytochrome c-L moxG 0.0007
4981 Iron-starvation protein PigA pigA 0.0007
644 Heme oxygenase 2 HMOX2 0.0007
4982 Heme oxygenase 2 pbsA2 0.0007
4942 Diheme cytochrome c napB napB 0.0007
4961 Hemophore HasA hasA 0.0007
4935 Cytochrome c-554 cycA1 0.0007
4971 Nonaheme cytochrome c hmcA 0.0007
4904 Cytochrome c family protein GSU1996 0.0007
4976 Apocytochrome f petA 0.0007
6407 Apocytochrome f petA 0.0007
4999 Cytochrome P450 165B3 CYP165B3 0.0007
4764 Cytochrome P450 165C4 CYP165C4 0.0007
4937 Cytochrome oxidase subunit II rcoxA 0.0007
4960 Putative cytochrome P450-family protein SCO7417 0.0007
4931 Cytochrome P450 167A1 CYP167A1 0.0007
4989 Cytochrome c551 peroxidase ccp 0.0007
5222 Cytochrome c551 peroxidase ccpA 0.0007
4903 Methyl-accepting chemotaxis protein Tar4 0.0007
4922 Cytochrome c, putative SO_4144 0.0007
4970 Cytochrome c nitrite reductase catalytic subunit nrfA 0.0007
4926 Heme-based aerotactic transducer hemAT hemAT 0.0007
4972 P450cin cinA 0.0007
4993 Hydroxylamine oxidoreductase hao1 0.0007
4908 Heme-regulated cyclic AMP phosphodiesterase dosP 0.0007
3093 Catalase HPII katE 0.0007
4952 Catalase/peroxidase katA 0.0007
6034 Hydroxyindole O-methyltransferase ASMT 0.0007
6035 Nuclear receptor ROR-beta RORB 0.0007
6036 Eosinophil peroxidase EPX 0.0007
6344 ATP synthase subunit gamma, mitochondrial ATP5C1 0.0007
6343 ATP synthase subunit beta, mitochondrial ATP5B 0.0007
6342 ATP synthase subunit alpha, mitochondrial ATP5A1 0.0007
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0007
933 Proto-oncogene tyrosine-protein kinase Src SRC 0.0007
4192 DNA topoisomerase 2-beta TOP2B 0.0007
6259 (3R)-hydroxymyristoyl-acyl carrier protein dehydratase fabZ 0.0006
765 Indoleamine 2,3-dioxygenase IDO1 0.0006
806 Sodium/potassium-transporting ATPase alpha-1 chain ATP1A1 0.0006
2404 Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform PIK3CG 0.0006
2449 Tubulin alpha-3 chain TUBA1A 0.0006
828 Phenylalanine-4-hydroxylase PAH 0.0006
3109 Phenylalanine-4-hydroxylase phhA 0.0006
5221 Cytochrome c3, 13 kDa Not Available 0.0006
3152 Cytochrome c'' cycA 0.0006
5220 Split-Soret cytochrome c Ddes_2150 0.0006
3700 Cytochrome c-552 precursor nrfA 0.0006
33 Cystine/glutamate transporter SLC7A11 0.0005
543 Penicillin-binding protein 1B mrcB 0.0005
6186 Penicillin-binding protein 1B ponB 0.0005
6822 Penicillin-binding protein 1b pbp1b 0.0005
6844 Penicillin-binding protein 1b pbp1b 0.0005
3961 G protein-activated inward rectifier potassium channel 4 KCNJ5 0.0005
4920 Peroxidase/catalase katG 0.0005
645 Penicillin-binding protein 1A mrcA 0.0005
5805 Penicillin-binding protein 1A ponA 0.0005
6185 Penicillin-binding protein 1A mrcA 0.0005
6799 Penicillin-binding protein 1A pbpA 0.0005
159 Penicillin-binding protein 2B penA 0.0005
6121 Penicillin-binding protein 2B penA 0.0005
2347 Proto-oncogene serine/threonine-protein kinase Pim-1 PIM1 0.0005
2119 Cytochrome b5 CYB5A 0.0005
4990 PpcA ppcA 0.0005
4956 Quinohemoprotein alcohol dehydrogenase ADH IIB qbdA 0.0005
3375 Acidic cytochrome c3 Not Available 0.0005
4988 Sulfite oxidase, mitochondrial SUOX 0.0005
2915 Sensor protein fixL fixL 0.0005
4944 Sensor protein fixL fixL 0.0005
4385 Cytochrome c' Not Available 0.0005
4967 Cytochrome c' cycA 0.0005
5038 Cytochrome c' Not Available 0.0005
5223 Cytochrome c' cycP 0.0005
3570 Cytochrome P450 152A1 cypC 0.0005
4037 Hypothetical protein GPX1 0.0005
4297 Hypothetical protein SP_1951 0.0005
4521 Hypothetical protein BC_2969 0.0005
4540 Hypothetical protein TM_1070 0.0005
4555 Hypothetical protein MT1739 0.0005
4569 Hypothetical protein mshD 0.0005
4578 Hypothetical protein PA3270 0.0005
4747 Hypothetical protein PA3967 0.0005
5177 Hypothetical protein TM_0096 0.0005
5194 Hypothetical protein PA1204 0.0005
5240 Hypothetical protein Rv2991 0.0005
5370 Hypothetical protein TM_1158 0.0005
5710 Hypothetical protein Tb927.5.1360 0.0005
4813 Heme oxygenase hmuO 0.0005
5769 Heme oxygenase Not Available 0.0005
4992 Cytochrome c peroxidase Not Available 0.0005
4289 Cytochrome P450 TT_P0059 0.0005
6262 Cytochrome P450 staP 0.0005
3127 Nitrite reductase nirS 0.0005
3284 Nitrite reductase nirS 0.0005
233 Potassium channel subfamily K member 2 KCNK2 0.0005
521 ATP-binding cassette transporter sub-family C member 9 ABCC9 0.0005
3411 Cytochrome P450 121 cyp121 0.0005
3670 Soluble cytochrome b562 precursor cybC 0.0005
3291 Cytochrome c-552 cycA 0.0004
4927 Cytochrome c-552 nrfA 0.0004
4938 Cytochrome c-552 cycA 0.0004
4953 Cytochrome c-552 nrfA 0.0004
5217 Cytochrome c-552 cycM 0.0004
2617 Nitric oxide synthase oxygenase nos 0.0004
2701 Nitric oxide synthase oxygenase nos 0.0004
3102 Flavohemoprotein hmp 0.0004
4969 Flavohemoprotein hmp 0.0004
132 ATP-binding cassette sub-family A member 1 ABCA1 0.0004
3405 Quinohaemoprotein ethanol dehydrogenase type-1 qheDH 0.0004
2845 Bifunctional P-450:NADPH-P450 reductase CYP102A1 0.0004
2972 6-deoxyerythronolide B hydroxylase eryF 0.0004
605 Fumarate reductase flavoprotein subunit frdA 0.0004
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0004
3673 Fumarate reductase flavoprotein subunit fccA 0.0004
4912 Fumarate reductase flavoprotein subunit ifcA 0.0004
6549 Fumarate reductase flavoprotein subunit frdA 0.0004
6042 Prostaglandin reductase 2 PTGR2 0.0004
4608 Putative cytochrome P450 SCO1207 0.0004
4963 Putative cytochrome P450 SCO2884 0.0004
6254 Putative cytochrome P450 SCO6998 0.0004
6043 Putative G-protein coupled receptor 44 GPR44 0.0004
358 Cystathionine beta-synthase CBS 0.0004
693 Hemoglobin subunit beta HBB 0.0003
6268 Hydroxyacid oxidase 1 HAO1 0.0003
810 Heme oxygenase 1 HMOX1 0.0003
3391 Heme oxygenase 1 pbsA1 0.0003
1313 Lactoylglutathione lyase GLO1 0.0003
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