DT-Web

DB02633 - Cibacron Blue


Identification
Name Cibacron Blue
Accession Number DB02633 (EXPT00841)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 774.157
Groups experimental
Monoisotopic Weight 773.007144294
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


NAD(P)H dehydrogenase [quinone] 1
Name NAD(P)H dehydrogenase [quinone] 1
Gene Name NQO1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.7783
Glutathione S-transferase P
Name Glutathione S-transferase P
Gene Name GSTP1
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.5761

Predictions


Id Partner name Gene Name Score
896 Glutathione S-transferase Mu 1 GSTM1 0.0743
4031 Glutathione S-transferase A1 GSTA1 0.0587
4407 FMN-dependent NADH-azoreductase azoR 0.045
5169 FMN-dependent NADH-azoreductase azoR 0.045
901 Glutathione S-transferase Mu 4 GSTM4 0.0417
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0376
2936 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.036
5184 Oxygen-insensitive NAD(P)H nitroreductase nfnB 0.036
908 Glutathione S-transferase theta-1 GSTT1 0.0325
3759 Glutathione S-transferase gst 0.0325
4541 Glutathione S-transferase GST 0.0325
6163 Copper-transporting ATPase 2 ATP7B 0.0298
6165 Copper-transporting ATPase 1 ATP7A 0.0298
2159 Quinone oxidoreductase CRYZ 0.0297
6146 High affinity copper uptake protein 1 SLC31A1 0.0282
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0252
6139 Solute carrier organic anion transporter family member 1A2 SLCO1A2 0.0224
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0221
1757 Myeloperoxidase MPO 0.022
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0214
3947 Xanthine dehydrogenase/oxidase XDH 0.0213
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0206
3932 Glutathione S-transferase A2 GSTA2 0.0201
1313 Lactoylglutathione lyase GLO1 0.018
4041 Microsomal glutathione S-transferase 2 MGST2 0.0168
5898 Complement C3 C3 0.0154
2409 Acetyl-CoA acetyltransferase, cytosolic ACAT2 0.0139
4757 Cytochrome P450 2C9 CYP2C9 0.0129
6677 Myelin P2 protein PMP2 0.0122
899 Glutathione S-transferase Mu 3 GSTM3 0.012
905 Glutathione transferase omega-1 GSTO1 0.012
6137 Multidrug resistance-associated protein 6 ABCC6 0.0117
2517 Subtilisin BPN' apr 0.0116
4077 Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform PPP2CB 0.0115
86 SEC14-like protein 4 SEC14L4 0.0115
4076 Diacylglycerol kinase alpha DGKA 0.0115
375 SEC14-like protein 3 SEC14L3 0.0115
708 Alpha-tocopherol transfer protein TTPA 0.0115
283 SEC14-like protein 2 SEC14L2 0.0114
4078 Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform PPP2CA 0.0111
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.011
997 Protein kinase C beta type PRKCB 0.011
6013 Cytochrome P450 2E1 CYP2E1 0.0106
2596 Acetyl-CoA acetyltransferase phbA 0.0105
4200 Cytochrome P450 1A2 CYP1A2 0.0104
1588 Multidrug resistance protein 1 ABCB1 0.0103
1970 Protein kinase C alpha type PRKCA 0.0099
4512 Cytochrome P450 3A4 CYP3A4 0.0098
2443 Azurin azu 0.0097
6144 Solute carrier family 22 member 2 SLC22A2 0.0095
810 Heme oxygenase 1 HMOX1 0.0091
3391 Heme oxygenase 1 pbsA1 0.0091
186 Glutamate--cysteine ligase catalytic subunit GCLC 0.009
1898 Cytochrome P450 1B1 CYP1B1 0.0082
1284 Nuclear receptor subfamily 1 group I member 2 NR1I2 0.0077
6024 Cytochrome P450 1A1 CYP1A1 0.0073
275 Arachidonate 5-lipoxygenase ALOX5 0.007
400 Coagulation factor IX F9 0.0068
5461 Coagulation factor IX F9 0.0068
6136 Multidrug resistance-associated protein 5 ABCC5 0.0066
290 Prostaglandin G/H synthase 2 PTGS2 0.0066
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0064
604 Vitamin K-dependent protein Z PROZ 0.0064
6147 Solute carrier family 22 member 3 SLC22A3 0.0061
6432 Transporter snf 0.0061
468 Cytochrome P450 4A11 CYP4A11 0.0058
1245 Vitamin K-dependent protein S PROS1 0.0057
422 Vitamin K-dependent protein C PROC 0.0057
3923 Cholinesterase BCHE 0.0056
3709 Glycerol uptake facilitator protein glpF 0.0055
3116 Bacterioferritin bfr 0.0055
4906 Bacterioferritin bfr 0.0055
4965 Bacterioferritin bfr 0.0055
5489 Ribonucleoside-diphosphate reductase 1 subunit beta nrdB 0.0055
3173 Enolase eno 0.0055
3393 TGF-beta receptor type-2 TGFBR2 0.0055
3238 Multidrug resistance protein mexA mexA 0.0055
3336 C4-dicarboxylate transport transcriptional regulatory protein dctD dctD 0.0055
6148 Multidrug resistance-associated protein 7 ABCC10 0.0055
862 Multidrug resistance-associated protein 1 ABCC1 0.0055
6030 Cytochrome P450 2B6 CYP2B6 0.0054
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.0054
798 Osteocalcin BGLAP 0.0052
6145 Solute carrier family 22 member 1 SLC22A1 0.0052
817 DNA topoisomerase 2-alpha TOP2A 0.0051
2101 Glutathione-requiring prostaglandin D synthase HPGDS 0.0051
448 Vitamin K-dependent gamma-carboxylase GGCX 0.005
2852 DNA mismatch repair protein mutL mutL 0.0048
369 Coagulation factor VII F7 0.0048
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0045
6459 Glycodelin PAEP 0.0045
3191 Histidinol dehydrogenase hisD 0.0044
3221 Cytochrome c4 cc4 0.0044
5278 Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthetase 1 PAPSS1 0.0044
436 5-hydroxytryptamine 2B receptor HTR2B 0.0042
740 Argininosuccinate synthase ASS1 0.0041
865 Argininosuccinate synthase ASS1 0.0041
2680 Argininosuccinate synthase argG 0.0041
3194 Argininosuccinate synthase argG 0.0041
4192 DNA topoisomerase 2-beta TOP2B 0.0041
4311 tRNA TRDMT1 0.0041
4325 tRNA trmD 0.0041
4328 tRNA trmD 0.0041
4692 A/G-specific adenine glycosylase mutY 0.004
76 Nitric-oxide synthase, brain NOS1 0.0039
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0039
4120 NADPH--cytochrome P450 reductase POR 0.0039
4119 Cytochrome P450 2D6 CYP2D6 0.0039
2802 Endoglucanase G celCCG 0.0039
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0038
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0038
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0038
6316 ADP-ribosylation factor 1 ARF1 0.0038
590 5-hydroxytryptamine 2C receptor HTR2C 0.0037
6168 Solute carrier family 22 member 16 SLC22A16 0.0037
3917 Methylenetetrahydrofolate reductase MTHFR 0.0037
824 Sodium-dependent serotonin transporter SLC6A4 0.0037
540 Sodium-dependent noradrenaline transporter SLC6A2 0.0037
239 Coagulation factor X F10 0.0037
5448 Ribonuclease Z rnz 0.0035
5449 Hypothetical gliding protein mglB 0.0035
3781 Thiol:disulfide interchange protein dsbC precursor dsbC 0.0035
4705 Manganese catalase Not Available 0.0035
5439 33 kDa chaperonin hslO 0.0035
332 Beta-lactamase blaZ 0.0035
2478 Beta-lactamase ampC 0.0035
2613 Beta-lactamase ampC 0.0035
2635 Beta-lactamase ampC 0.0035
2700 Beta-lactamase penP 0.0035
5445 Beta-lactamase blaB 0.0035
6019 Beta-lactamase SHV-7 0.0035
6701 Beta-lactamase cphA 0.0035
5443 UPF0189 protein ymdB ymdB 0.0035
5446 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase HI_1679 0.0035
5440 UPF0067 protein yebR yebR 0.0035
2720 Copper-containing nitrite reductase nirK 0.0035
5454 Internalin-A inlA 0.0035
6020 Aldehyde oxidase AOX1 0.0035
5447 Lethal(3)malignant brain tumor-like protein L3MBTL1 0.0035
4498 Ornithine cyclodeaminase PP3533 0.0034
502 5-hydroxytryptamine 2A receptor HTR2A 0.0033
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0033
444 Alcohol dehydrogenase 1B ADH1B 0.0033
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0033
6270 Group IIE secretory phospholipase A2 PLA2G2E 0.0032
5450 Prolyl endopeptidase Pep pep 0.0031
4771 Dissimilatory copper-containing nitrite reductase nir 0.0031
3356 Diaminopimelate decarboxylase lysA 0.0031
2714 Chorismate mutase aroH 0.0031
4611 Chorismate mutase aroG 0.0031
3274 Hydroxylamine reductase hcp 0.0031
4804 Hydroxylamine reductase hcp 0.0031
54 Prothrombin F2 0.0031
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.003
587 Serum albumin ALB 0.003
3399 Limonene-1,2-epoxide hydrolase limA 0.0029
3462 Tyrosine-protein kinase transforming protein Abl ABL 0.0028
3697 Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase glmU 0.0028
597 Dihydropteridine reductase QDPR 0.0028
5180 L(+)-mandelate dehydrogenase mdlB 0.0027
3500 Putative family 31 glucosidase yicI yicI 0.0027
714 Glutathione reductase, mitochondrial GSR 0.0027
4608 Putative cytochrome P450 SCO1207 0.0027
4963 Putative cytochrome P450 SCO2884 0.0027
6254 Putative cytochrome P450 SCO6998 0.0027
7 Nitric oxide synthase, inducible NOS2 0.0027
3480 Mannan endo-1,4-beta-mannosidase manA 0.0027
577 Argininosuccinate lyase ASL 0.0026
6022 UDP-glucuronosyltransferase 1-1 UGT1A1 0.0026
291 Nitric-oxide synthase, endothelial NOS3 0.0026
6016 Cytochrome P450 2C19 CYP2C19 0.0026
1615 Chymase CMA1 0.0026
5718 Cytochrome P450 2A6 CYP2A6 0.0026
2597 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] glmS 0.0025
365 Dihydrofolate reductase DHFR 0.0024
2381 Dihydrofolate reductase DFR1 0.0024
2833 Dihydrofolate reductase Not Available 0.0024
2931 Dihydrofolate reductase folA 0.0024
3544 Dihydrofolate reductase folA 0.0024
3682 Dihydrofolate reductase folA 0.0024
6642 Dihydrofolate reductase folA 0.0024
6756 Dihydrofolate reductase dfrA 0.0024
4035 Glutathione S-transferase Mu 5 GSTM5 0.0024
900 Glutathione S-transferase A4 GSTA4 0.0024
903 Glutathione S-transferase A5 GSTA5 0.0024
4037 Hypothetical protein GPX1 0.0024
4297 Hypothetical protein SP_1951 0.0024
4521 Hypothetical protein BC_2969 0.0024
4540 Hypothetical protein TM_1070 0.0024
4555 Hypothetical protein MT1739 0.0024
4569 Hypothetical protein mshD 0.0024
4578 Hypothetical protein PA3270 0.0024
4747 Hypothetical protein PA3967 0.0024
5177 Hypothetical protein TM_0096 0.0024
5194 Hypothetical protein PA1204 0.0024
5240 Hypothetical protein Rv2991 0.0024
5370 Hypothetical protein TM_1158 0.0024
5710 Hypothetical protein Tb927.5.1360 0.0024
1928 Leukotriene C4 synthase LTC4S 0.0024
4043 Glutaredoxin-2, mitochondrial GLRX2 0.0024
4034 Glutaredoxin-1 GLRX 0.0024
906 Glutathione peroxidase 1 GPX1 0.0024
4039 CDNA FLJ23636 fis, clone CAS07176 GPX8 0.0024
4036 Glutathione peroxidase 6 GPX6 0.0024
911 Glutathione peroxidase 3 GPX3 0.0024
4042 Glutathione transferase omega-2 GSTO2 0.0024
4029 Microsomal glutathione S-transferase 3 MGST3 0.0024
4032 Microsomal glutathione S-transferase 1 MGST1 0.0024
910 Epididymal secretory glutathione peroxidase GPX5 0.0024
4033 S-formylglutathione hydrolase ESD 0.0024
4030 Thioredoxin domain-containing protein 12 TXNDC12 0.0024
4040 Glutathione peroxidase 7 GPX7 0.0024
907 Glutathione peroxidase 2 GPX2 0.0024
4038 Glutathione peroxidase 4 GPX4 0.0024
1975 Phospholipid hydroperoxide glutathione peroxidase, mitochondrial GPX4 0.0024
287 Beta-1,4-galactosyltransferase 1 B4GALT1 0.0024
1056 Gamma-glutamyltranspeptidase 1 GGT1 0.0024
898 Glutathione S-transferase A3 GSTA3 0.0023
897 Glutathione S-transferase kappa 1 GSTK1 0.0023
3319 Hydroxyacylglutathione hydrolase HAGH 0.0023
909 Maleylacetoacetate isomerase GSTZ1 0.0023
776 Bile salt export pump ABCB11 0.0022
20 Prostaglandin G/H synthase 1 PTGS1 0.0022
2165 Glutathione S-transferase Mu 2 GSTM2 0.0021
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0019
5122 Mersacidin decarboxylase mrsD 0.0019
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0019
5095 Putidaredoxin reductase camA 0.0019
3763 5,10-methylenetetrahydrofolate reductase metF 0.0019
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0019
5094 5,10-methylenetetrahydrofolate reductase metF 0.0019
526 Thioredoxin reductase trxB 0.0019
3767 Thioredoxin reductase trxB 0.0019
5078 Amine oxidase, flavin-containing PSPTO1126 0.0019
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0019
5109 Outer membrane protein p64k or PM-6 m-6 0.0019
5115 FkbI fkbI 0.0019
5083 Cryptochrome DASH cry 0.0019
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0019
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0019
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0019
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0019
5081 L-aspartate oxidase nadB 0.0019
1410 Oxidoreductase HSD17B6 0.0019
4725 Oxidoreductase Not Available 0.0019
5124 Oxidoreductase Not Available 0.0019
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0019
3133 UDP-galactopyranose mutase glf 0.0019
5099 UDP-galactopyranose mutase glf 0.0019
5111 Phenylacetone monooxygenase pamO 0.0019
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0019
4118 Cytochrome P450 3A5 CYP3A5 0.0019
207 Glutathione synthetase GSS 0.0019
5269 Glutathione synthetase gshB 0.0019
4924 Cytochrome P450 2C8 CYP2C8 0.0019
4486 Phenol 2-hydroxylase component B pheA2 0.0018
4477 Dihydrolipoyl dehydrogenase lpdV 0.0018
5077 Dihydrolipoyl dehydrogenase Not Available 0.0018
5117 Dihydrolipoyl dehydrogenase lpd 0.0018
4439 Ferredoxin reductase bphA4 0.0018
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0017
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0017
2268 Cholesterol oxidase choB 0.0017
2822 Cholesterol oxidase choA 0.0017
5072 N,N-dimethylglycine oxidase dmg 0.0017
5073 Ferredoxin--NADP reductase petH 0.0017
5076 Ferredoxin--NADP reductase fpr 0.0017
5119 Ferredoxin--NADP reductase petH 0.0017
5121 Ferredoxin--NADP reductase fpr 0.0017
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0017
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0017
3594 Deoxyribodipyrimidine photo-lyase phr 0.0017
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0017
5080 Deoxyribodipyrimidine photo-lyase phr 0.0017
2526 NADPH-ferredoxin reductase fprA fprA 0.0017
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0017
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0017
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0017
2470 Pyruvate oxidase pox5 0.0017
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0017
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.0017
3102 Flavohemoprotein hmp 0.0016
4969 Flavohemoprotein hmp 0.0016
4440 NADH peroxidase npr 0.0016
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.0015
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.0015
2893 Glycine oxidase thiO 0.0015
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0015
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0015
327 Glutathione reductase gor 0.0015
5110 Glutathione reductase GR2 0.0015
126 D-lactate dehydrogenase dld 0.0015
3545 D-lactate dehydrogenase Not Available 0.0015
4510 D-lactate dehydrogenase ldhA 0.0015
474 Acetylcholinesterase ACHE 0.0015
2567 Thymidylate synthase thyX thyX 0.0015
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0015
2823 Trypanothione reductase TPR 0.0015
605 Fumarate reductase flavoprotein subunit frdA 0.0014
2709 Fumarate reductase flavoprotein subunit SO_0970 0.0014
3673 Fumarate reductase flavoprotein subunit fccA 0.0014
4912 Fumarate reductase flavoprotein subunit ifcA 0.0014
6549 Fumarate reductase flavoprotein subunit frdA 0.0014
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0014
2769 P-hydroxybenzoate hydroxylase pobA 0.0014
2809 P-hydroxybenzoate hydroxylase pobA 0.0014
2380 Monomeric sarcosine oxidase soxA 0.0013
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0013
6645 D-amino-acid oxidase DAO 0.0013
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0012
2164 Multidrug resistance-associated protein 4 ABCC4 0.0011
3939 Amine oxidase [flavin-containing] B MAOB 0.0008
3941 Amine oxidase [flavin-containing] A MAOA 0.0008
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