DT-Web

DB03798 - 2'-Deoxycytidine-5'-Monophosphate


Identification
Name 2'-Deoxycytidine-5'-Monophosphate
Accession Number DB03798 (EXPT01134)
Type small molecule
Description Deoxycytidine (dihydrogen phosphate). A deoxycytosine nucleotide containing one phosphate group esterified to the deoxyribose moiety in the 2'-,3'- or 5- positions. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 307.1971
Groups experimental
Monoisotopic Weight 307.056936329
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Deoxycytidylate 5-hydroxymethyltransferase
Name Deoxycytidylate 5-hydroxymethyltransferase
Gene Name 42
Pharmacological action unknown
Actions Not Available
References Not Available
DTHybrid score 1.1243
Thymidylate synthase
Name Thymidylate synthase
Gene Name thyA
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.0494

Predictions


Id Partner name Gene Name Score
2567 Thymidylate synthase thyX thyX 0.0705
3586 Thymidylate synthase A thyA1 0.0624
2717 Folylpolyglutamate synthase fgs 0.0587
24 Thymidylate synthase TMP1 0.0494
359 Thymidylate synthase TYMS 0.0494
2626 Thymidylate synthase thyA 0.0494
5352 Thymidylate synthase THYA 0.0494
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.026
3529 Interferon-stimulated gene 20 kDa protein ISG20 0.0249
3575 Uracil phosphoribosyltransferase upp 0.0249
3600 Uracil phosphoribosyltransferase upp 0.0249
3056 Orotidine 5'-phosphate decarboxylase pyrF 0.0249
3564 Orotidine 5'-phosphate decarboxylase pyrF 0.0249
2410 Deoxyuridine 5'-triphosphate nucleotidohydrolase dut 0.0235
2490 Deoxyuridine 5'-triphosphate nucleotidohydrolase dut 0.0235
4276 DNA polymerase III subunit epsilon dnaQ 0.0216
4275 PCZA361.16 Not Available 0.0216
2344 Ribosomal small subunit pseudouridine synthase A rsuA 0.0215
3706 Ribosomal small subunit pseudouridine synthase A rsuA 0.0215
2555 Pol polyprotein pol 0.0214
3242 Pol polyprotein gag-pol 0.0214
3471 Pol polyprotein gag-pro-pol 0.0214
5256 Pol polyprotein pol 0.0214
6469 Pol polyprotein gag-pol 0.0214
6565 Pol polyprotein Not Available 0.0214
3257 Bifunctional polymyxin resistance protein arnA arnA 0.0214
1353 DNA topoisomerase 1 TOP1 0.0204
3552 DNA topoisomerase 1 topA 0.0204
2590 Galactose-1-phosphate uridylyltransferase galT 0.0199
2966 PyrR bifunctional protein [Includes: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase pyrR 0.0198
2251 Thymidylate kinase tmk 0.018
2254 Thymidylate kinase DTYMK 0.018
3522 Thymidylate kinase tmk 0.018
3478 Glucose-1-phosphate thymidylyltransferase rmlA 0.0179
4277 Glucose-1-phosphate thymidylyltransferase rmlA 0.0179
287 Beta-1,4-galactosyltransferase 1 B4GALT1 0.016
509 Thymidine kinase TK 0.015
570 Thymidine kinase TK 0.015
2559 Thymidine kinase TK 0.015
3430 Thymidine kinase tdk 0.015
3518 Thymidine kinase TK 0.015
5301 Thymidine kinase tdk 0.015
5771 Thymidine kinase ORF36 0.015
7009 Thymidine kinase ORF36 0.015
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