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PyrR bifunctional protein [Includes: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase


Partner ID 2966
Name PyrR bifunctional protein [Includes: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase
Synonyms 4961
Gene name pyrR
General function Nucleotide transport and metabolism
Specific function Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Gene sequence + ...

ATGCAAAAGGCGGTCGTGATGGACGAACAGGCGATTCGCCGCGCTTTGACGCGCATCGCCCACGAAATCATCGAACGAAACAAAGGCATTGACGGCTGCGTGCTTGTCGGAATTAAAACGCGCGGCATTTACTTGGCGCGCCGCTTGGCGGAGCGGATCGAGCAAATTGAAGGGGCGTCCGTTCCCGTCGGTGAGCTTGACATCACCTTGTACCGCGACGATTTGACCGTGAAGACGGACGACCATGAACCGCTTGTGAAAGGAACGAATGTGCCGTTTCCGGTGACCGAGCGGAATGTCATTTTAGTTGATGACGTGCTCTTCACCGGCCGGACGGTGCGGGCGGCGATGGATGCGGTCATGGATTTGGGCCGCCCGGCGCGCATCCAGCTCGCCGTGCTTGTTGACCGCGGCCACAGGGAACTCCCGATCCGCGCTGATTTCGTCGGCAAAAACGTGCCGACCTCTCGTTCGGAACTGATCGTCGTGGAGCTTTCGGAAGTGGACGGCATCGATCAAGTCTCCATTCATGAAAAATAG
Protein sequence + ...

MQKAVVMDEQAIRRALTRIAHEIIERNKGIDGCVLVGIKTRGIYLARRLAERIEQIEGASVPVGELDITLYRDDLTVKTDDHEPLVKGTNVPFPVTERNVILVDDVLFTGRTVRAAMDAVMDLGRPARIQLAVLVDRGHRELPIRADFVGKNVPTSRSELIVVELSEVDGIDQVSIHEK
GO Classification
function
catalytic activity
transferase activity
process
physiological process
metabolism
cellular metabolism
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
nucleoside metabolism
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB01972 Guanosine-5'-Monophosphate
DB03315 Guanosine-3'-Monophosphate
DB03685 Uridine-5'-Monophosphate

Associated as Prediction

Id Name
DB00116 Tetrahydrofolic acid
DB00130 L-Glutamine
DB00131 Adenosine monophosphate
DB00141 N-Acetyl-D-glucosamine
DB00203 Sildenafil
DB00277 Theophylline
DB00563 Methotrexate
DB00642 Pemetrexed
DB00806 Pentoxifylline
DB00820 Tadalafil
DB00862 Vardenafil
DB00975 Dipyridamole
DB01643 Thymidine-5'-Phosphate
DB01700 Aicar
DB01861 Glucose-Uridine-C1,5'-Diphosphate
DB01864 5'-Guanosine-Diphosphate-Monothiophosphate
DB01972 Guanosine-5'-Monophosphate
DB02134 Xanthine
DB02162 5'-O-(N-Ethyl-Sulfamoyl)Adenosine
DB02183 Adenosine-5'-Ditungstate
DB02212 Pyrophosphate 2-
DB02301 5,10-Methylene-6-Hydrofolic Acid
DB02309 5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine
DB02377 Guanine
DB02696 6-Aminohexyl-Uridine-C1,5'-Diphosphate
DB02857 Guanosine
DB03013 Di(N-Acetyl-D-Glucosamine)
DB03152 B-2-Octylglucoside
DB03256 5-Formyl-5,6,7,8-Tetrahydrofolate
DB03315 Guanosine-3'-Monophosphate
DB03349 8-Bromo-Adenosine-5'-Monophosphate
DB03419 Uracil
DB03431 Adenosine-5'-Diphosphate
DB03435 Uridine-5'-Diphosphate
DB03442 2-[5-Hydroxy-3-Methyl-1-(2-Methyl-4-Sulfo-Phenyl)-1h-Pyrazol-4-Ylazo]-4-Sulfo-Benzoic Acid
DB03501 Uridine Diphosphate Galactose
DB03541 10-Propargyl-5,8-Dideazafolic Acid
DB03597 Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine
DB03685 Uridine-5'-Monophosphate
DB03761 5-Fluoro-2'-Deoxyuridine-5'-Monophosphate
DB03798 2'-Deoxycytidine-5'-Monophosphate
DB03800 2'-deoxyuridylic acid
DB03814 2-(N-Morpholino)-Ethanesulfonic Acid
DB03942 Carboxylic PRPP
DB04057 Beta-Dadf, Msa, Multisubstrate Adduct Inhibitor
DB04272 Citric Acid
DB04296 5-Oxo-L-Norleucine
DB04315 Guanosine-5'-Diphosphate
DB06237 Avanafil
DB06267 Udenafil
DB06860 2-(2-chloropyridin-4-yl)-4-methyl-1H-isoindole-1,3(2H)-dione
DB07507 2-(4-hydroxybiphenyl-3-yl)-4-methyl-1H-isoindole-1,3(2H)-dione
DB07511 4-(4-methyl-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzonitrile
DB07954 3-ISOBUTYL-1-METHYLXANTHINE
DB08204 3-DIPHENOL-6-NITRO-3H-BENZO[DE]ISOCHROMEN-1-ONE
DB08245 1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-5-NITRO-1H-INDOLE
DB08729 5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide
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