DT-Web

DB03942 - Carboxylic PRPP


Identification
Name Carboxylic PRPP
Accession Number DB03942 (EXPT02523)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 388.0968
Groups experimental
Monoisotopic Weight 387.972550102
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Amidophosphoribosyltransferase
Name Amidophosphoribosyltransferase
Gene Name purF
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.0851
Pur operon repressor
Name Pur operon repressor
Gene Name purR
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.0901
Xanthine phosphoribosyltransferase
Name Xanthine phosphoribosyltransferase
Gene Name gpt
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.2061

Predictions


Id Partner name Gene Name Score
3300 Xanthine phosphoribosyltransferase xpt 1.2061
2837 Xanthosine phosphorylase xapA 0.3429
1673 GTP cyclohydrolase I GCH1 0.1126
3302 GTP cyclohydrolase I folE 0.1126
2361 Response regulator pleD pleD 0.0977
2516 GMP reductase 1 GMPR 0.0976
413 Amidophosphoribosyltransferase PPAT 0.0851
2515 Amidophosphoribosyltransferase purF 0.0851
4553 Bifunctional adenosylcobalamin biosynthesis protein cobU cobU 0.0851
4106 Guanylate kinase GUK1 0.085
4516 Guanylate kinase gmk 0.085
2966 PyrR bifunctional protein [Includes: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase pyrR 0.0785
338 DNA polymerase UL30 0.0783
379 DNA polymerase UL54 0.0783
697 DNA polymerase ORF28 0.0783
2482 DNA polymerase 43 0.0783
4104 DNA polymerase BALF5 0.0783
2684 Histidine triad nucleotide-binding protein 1 HINT1 0.0673
2339 Protein-glutamine gamma-glutamyltransferase E TGM3 0.0657
277 Purine nucleoside phosphorylase PNP 0.0605
2870 Purine nucleoside phosphorylase punA 0.0605
2945 Purine nucleoside phosphorylase punA 0.0605
4659 Purine nucleoside phosphorylase TM_1596 0.0605
4825 Purine nucleoside phosphorylase TTHA1435 0.0605
2287 Bifunctional purine biosynthesis protein PURH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase ATIC 0.0556
204 cGMP-specific 3',5'-cyclic phosphodiesterase PDE5A 0.0485
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