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Xanthine phosphoribosyltransferase


Partner ID 3681
Name Xanthine phosphoribosyltransferase
Synonyms 5697
Gene name gpt
General function Nucleotide transport and metabolism
Specific function Acts on guanine, xanthine and to a lesser extent hypoxanthine
Gene sequence + ...

ATGAGCGAAAAATACATCGTCACCTGGGACATGTTGCAGATCCATGCACGTAAACTCGCAAGCCGACTGATGCCTTCTGAACAATGGAAAGGCATTATTGCCGTAAGCCGTGGCGGTCTGGTACCGGGTGCGTTACTGGCGCGTGAACTGGGTATTCGTCATGTCGATACCGTTTGTATTTCCAGCTACGATCACGACAACCAGCGCGAGCTTAAAGTGCTGAAACGCGCAGAAGGCGATGGCGAAGGCTTCATCGTTATTGATGACCTGGTGGATACCGGTGGTACTGCGGTTGCGATTCGTGAAATGTATCCAAAAGCGCACTTTGTCACCATCTTCGCAAAACCGGCTGGTCGTCCGCTGGTTGATGACTATGTTGTTGATATCCCGCAAGATACCTGGATTGAACAGCCGTGGGATATGGGCGTCGTATTCGTCCCGCCAATCTCCGGTCGCTAA
Protein sequence + ...

MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGALLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIREMYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR
GO Classification
function
catalytic activity
transferase activity
process
physiological process
metabolism
cellular metabolism
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
nucleoside metabolism
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB01972 Guanosine-5'-Monophosphate
DB02134 Xanthine
DB02377 Guanine
DB03942 Carboxylic PRPP

Associated as Prediction

Id Name
DB00116 Tetrahydrofolic acid
DB00130 L-Glutamine
DB00131 Adenosine monophosphate
DB00203 Sildenafil
DB00242 Cladribine
DB00277 Theophylline
DB00563 Methotrexate
DB00642 Pemetrexed
DB00806 Pentoxifylline
DB00820 Tadalafil
DB00862 Vardenafil
DB00900 Didanosine
DB00975 Dipyridamole
DB01667 8-azaguanine
DB01700 Aicar
DB01864 5'-Guanosine-Diphosphate-Monothiophosphate
DB01972 Guanosine-5'-Monophosphate
DB02134 Xanthine
DB02162 5'-O-(N-Ethyl-Sulfamoyl)Adenosine
DB02183 Adenosine-5'-Ditungstate
DB02212 Pyrophosphate 2-
DB02222 2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine
DB02230 Immucillin-G
DB02309 5--Monophosphate-9-Beta-D-Ribofuranosyl Xanthine
DB02377 Guanine
DB02391 2-Amino-7-[2-(2-Hydroxy-1-Hydroxymethyl-Ethylamino)-Ethyl]-1,7-Dihydro-Purin-6-One
DB02568 Peldesine
DB02796 9-Deazainosine
DB02857 Guanosine
DB03101 Ribose-1-Phosphate
DB03152 B-2-Octylglucoside
DB03315 Guanosine-3'-Monophosphate
DB03349 8-Bromo-Adenosine-5'-Monophosphate
DB03431 Adenosine-5'-Diphosphate
DB03442 2-[5-Hydroxy-3-Methyl-1-(2-Methyl-4-Sulfo-Phenyl)-1h-Pyrazol-4-Ylazo]-4-Sulfo-Benzoic Acid
DB03551 4'-Deaza-1'-Aza-2'-Deoxy-1'-(9-Methylene)-Immucillin-H, (3r,4r)-N-[9-Deazahypoxanthin-9-Yl)Methyl]-4-Hydroxymethyl-Pyrrolidin-3-Ol
DB03597 Gamma-Glutamyl[S-(2-Iodobenzyl)Cysteinyl]Glycine
DB03609 3-Deoxyguanosine
DB03685 Uridine-5'-Monophosphate
DB03881 MT-Immucillin-H
DB03942 Carboxylic PRPP
DB04022 Guanosine-5',3'-Tetraphosphate
DB04057 Beta-Dadf, Msa, Multisubstrate Adduct Inhibitor
DB04076 Hypoxanthine
DB04260 9-(5,5-Difluoro-5-Phosphonopentyl)Guanine
DB04272 Citric Acid
DB04296 5-Oxo-L-Norleucine
DB04315 Guanosine-5'-Diphosphate
DB04753 9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE
DB04754 GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE
DB04757 GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE
DB06237 Avanafil
DB06267 Udenafil
DB07954 3-ISOBUTYL-1-METHYLXANTHINE
DB08245 1-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-5-NITRO-1H-INDOLE
DB08729 5-ethoxy-4-(1-methyl-7-oxo-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-5-yl)thiophene-2-sulfonamide
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