DT-Web

DB04022 - Guanosine-5',3'-Tetraphosphate


Identification
Name Guanosine-5',3'-Tetraphosphate
Accession Number DB04022 (EXPT01534)
Type small molecule
Description Guanosine 5'-diphosphate 2'(3')-diphosphate. A guanine nucleotide containing four phosphate groups. Two phosphate groups are esterified to the sugar moiety in the 5' position and the other two in the 2' or 3' position. This nucleotide serves as a messenger to turn off the synthesis of ribosomal RNA when amino acids are not available for protein synthesis. Synonym: magic spot I. [PubChem]
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 603.1603
Groups experimental
Monoisotopic Weight 602.956990191
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Xanthine phosphoribosyltransferase
Name Xanthine phosphoribosyltransferase
Gene Name xpt
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.8521
Spo0B-associated GTP-binding protein
Name Spo0B-associated GTP-binding protein
Gene Name obg
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.8521

Predictions


Id Partner name Gene Name Score
3681 Xanthine phosphoribosyltransferase gpt 1.8521
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