| Name |
Deoxycytidylate 5-hydroxymethyltransferase |
| Synonyms |
7423 |
| Gene name |
42 |
| General function |
Involved in thymidylate synthase activity |
| Specific function |
5,10-methylenetetrahydrofolate + H(2)O + deoxycytidylate = tetrahydrofolate + 5- hydroxymethyldeoxycytidylate |
| Gene sequence |
+ ...
ATGATTAGTGACTCTATGACAGTTGAAGAAATCCGTCTTCATTTGGGGCTTGCATTAAAAGAAAAAGATTTCGTAGTTGATAAAACAGGTGTTAAAACTATTGAAATTATTGGCGCATCATTTGTAGCAGATGAACCGTTTATTTTTGGCGCTCTTAATGATGAATACATTCAGCGTGAACTTGAATGGTATAAATCTAAAAGCTTGTTCGTTAAAGATATTCCGGGTGAAACACCGAAGATTTGGCAACAAGTAGCATCTTCTAAAGGTGAAATTAACTCGAATTATGGTTGGGCTATCTGGTCAGAAGATAACTATGCTCAGTATGACATGTGTTTAGCTGAACTTGGTCAAAATCCTGATTCTCGACGTGGTATCATGATTTATACTCGTCCATCTATGCAGTTTGACTATAATAAAGATGGTATGTCAGATTTCATGTGCACGAATACAGTACAATACCTGATTCGTGACAAGAAAATCAATGCGGTTGTTAACATGCGCTCAAATGACGTGGTCTTCGGATTCCGTAATGATTATGCATGGCAAAAATACGTATTAGATAAATTAGTATCTGATTTGAATGCAGGTGATTCAACTCGCCAGTATAAAGCAGGTTCCATTATATGGAATGTTGGAAGCCTACATGTGTATTCTCGTCATTTTTATTTGGTTGATCATTGGTGGAAAACTGGCGAAACACATATTTCGAAAAAAGATTATGTAGGAAAATACGCTTAA
|
| Protein sequence |
+ ...
MISDSMTVEEIRLHLGLALKEKDFVVDKTGVKTIEIIGASFVADEPFIFGALNDEYIQRELEWYKSKSLFVKDIPGETPKIWQQVASSKGEINSNYGWAIWSEDNYAQYDMCLAELGQNPDSRRGIMIYTRPSMQFDYNKDGMSDFMCTNTVQYLIRDKKINAVVNMRSNDVVFGFRNDYAWQKYVLDKLVSDLNAGDSTRQYKAGSIIWNVGSLHVYSRHFYLVDHWWKTGETHISKKDYVGKYA
|
| GO Classification |
| function |
| catalytic activity |
| transferase activity |
| transferase activity, transferring one-carbon groups |
| methyltransferase activity |
| 5,10-methylenetetrahydrofolate-dependent methyltransferase activity |
| thymidylate synthase activity |
| process |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolism |
| nucleotide metabolism |
| pyrimidine nucleotide metabolism |
| pyrimidine nucleotide biosynthesis |
| physiological process |
| pyrimidine nucleoside monophosphate biosynthesis |
| pyrimidine deoxyribonucleoside monophosphate biosynthesis |
| metabolism |
| dTMP biosynthesis |
| cellular metabolism |
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www.drugbank.ca
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