| Name |
Deoxyuridine 5'-triphosphate nucleotidohydrolase |
| Synonyms |
3934 |
| Gene name |
dut |
| General function |
Nucleotide transport and metabolism |
| Specific function |
This enzyme is involved in nucleotide metabolism:it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA |
| Gene sequence |
+ ...
ATGAAAAAAATCGACGTTAAGATTCTGGACCCGCGCGTTGGGAAGGAATTTCCGCTCCCGACTTATGCCACCTCTGGCTCTGCCGGACTTGACCTGCGTGCCTGTCTCAACGACGCCGTAGAACTGGCTCCGGGTGACACTACGCTGGTTCCGACCGGGCTGGCGATTCATATTGCCGATCCTTCACTGGCGGCAATGATGCTGCCGCGCTCCGGATTGGGACATAAGCACGGTATCGTGCTTGGTAACCTGGTAGGATTGATCGATTCTGACTATCAGGGCCAGTTGATGATTTCCGTGTGGAACCGTGGTCAGGACAGCTTCACCATTCAACCTGGCGAACGCATCGCCCAGATGATTTTTGTTCCGGTAGTACAGGCTGAATTTAATCTGGTGGAAGATTTCGACGCCACCGACCGCGGTGAAGGCGGCTTTGGTCACTCTGGTCGTCAGTAA
|
| Protein sequence |
+ ...
MKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLNDAVELAPGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVWNRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ
|
| GO Classification |
| function |
| catalytic activity |
| hydrolase activity |
| process |
| pyrimidine nucleoside triphosphate metabolism |
| pyrimidine deoxyribonucleoside triphosphate metabolism |
| dUTP metabolism |
| physiological process |
| metabolism |
| cellular metabolism |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolism |
| nucleotide metabolism |
| pyrimidine nucleotide metabolism |
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www.drugbank.ca
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