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Ribosomal small subunit pseudouridine synthase A


Partner ID 2344
Name Ribosomal small subunit pseudouridine synthase A
Synonyms 4157
Gene name rsuA
General function Translation, ribosomal structure and biogenesis
Specific function Responsible for synthesis of pseudouridine from uracil- 516 in 16S ribosomal RNA
Gene sequence + ...

TTATTTTACTAACTTTTCAATTTCACTTTGAGTTAATGGGCGGTATTCGCCTTCTTCTAAGGATTCATCCAACACTACATCACCAATTTTCCAGCGATGTAATCCAACGACTTTATTCCCAAGTGCGGCAAACATACGTTTTACTTGATGATAACGACCTTCAGAAATGGTCAGATTCACATTGTAGTCATCTAAAATTTCTAATTTTGCTGGTTTAGTGGGCTCTTTTTCTCCGCGTAATAAAATGCCTTCTGCACAAGCTGCTGAATAATTTTCTTCTACGGGATCAGCTAATGTCACCAAATAGGTTTTTTCACAATGATGCTTTGGGGAAGTGATGCGATGTGACCATTGTCCATCATCGGTAAGCAATACGAGACCTGTCGTATCCACATCTAAGCGACCTGCGCTATGTAATTTTCCAGCTAAAGGGTAATCAAAAAATTGATAAATTGTTGGATAGTCGCCGTCATCATTAGAACAAACACAGCCTTGTGGTTTATTCAACATAAAATACTGGCCTTCTTCGATCCAAGTTAATAATTCATCTTCAAAATAAATTTCGTCTTCTTGTGAAATTTGAACCGAACCACTTTTGACAATTTCACCGTTGATTTTTACCGCACTTTGGCGGATCGCTTTTGTTGCTTGAGAACGAGTTAATCCCACATTTTCAGCAATAAATTTATCTAATCTCAT
Protein sequence + ...

MRLDKFIAENVGLTRSQATKAIRQSAVKINGEIVKSGSVQISQEDEIYFEDELLTWIEEGQYFMLNKPQGCVCSNDDGDYPTIYQFFDYPLAGKLHSAGRLDVDTTGLVLLTDDGQWSHRITSPKHHCEKTYLVTLADPVEENYSAACAEGILLRGEKEPTKPAKLEILDDYNVNLTISEGRYHQVKRMFAALGNKVVGLHRWKIGDVVLDESLEEGEYRPLTQSEIEKLVK
GO Classification
function
isomerase activity
carbon-oxygen lyase activity
hydro-lyase activity
binding
intramolecular transferase activity
pseudouridylate synthase activity
catalytic activity
pseudouridine synthase activity
lyase activity
nucleic acid binding
RNA binding
process
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
RNA metabolism
physiological process
metabolism
RNA processing
cellular metabolism
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB01955 1,4-Butanediol

Associated as Prediction

Id Name
DB00141 N-Acetyl-D-glucosamine
DB00233 Aminosalicylic Acid
DB00328 Indomethacin
DB00544 Fluorouracil
DB00586 Diclofenac
DB01101 Capecitabine
DB01381 Ginkgo biloba
DB01643 Thymidine-5'-Phosphate
DB01861 Glucose-Uridine-C1,5'-Diphosphate
DB01955 1,4-Butanediol
DB01972 Guanosine-5'-Monophosphate
DB02080 1-{2-[2-(2-Methoxyethoxy)Ethoxy]Ethoxy}-4-(1,1,3,3-Tetramethylbutyl)Benzene
DB02301 5,10-Methylene-6-Hydrofolic Acid
DB02303 (5s)-5-Iododihydro-2,4(1h,3h)-Pyrimidinedione
DB02338 Nadph Dihydro-Nicotinamide-Adenine-Dinucleotidephosphate
DB02422 Methyl-2-S-(Alpha-D-Mannopyranosyl)-2-Thio-Alpha-D-Mannopyranoside
DB02448 N-Tridecanoic Acid
DB02504 [3-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Propyl-]-Phosphonic Acid
DB02636 9-Hydroxy-8-Methoxy-6-Nitro-Phenanthrol[3,4-D][1,3]Dioxole-5-Carboxylic Acid
DB02696 6-Aminohexyl-Uridine-C1,5'-Diphosphate
DB02742 Kifunensine
DB02758 Indolylpropionic Acid
DB02795 P-Anisic Acid
DB02936 4-(1-Benzyl-3-Carbamoylmethyl-2-Methyl-1h-Indol-5-Yloxy)-Butyric Acid
DB02944 Alpha-D-Mannose
DB03013 Di(N-Acetyl-D-Glucosamine)
DB03048 6-Carboxymethyluracil
DB03121 1-Benzyl-5-Methoxy-2-Methyl-1h-Indol-3-Yl)-Acetic Acid
DB03147 Flavin-Adenine Dinucleotide
DB03206 1-Deoxynojirimycin
DB03247 Riboflavin Monophosphate
DB03256 5-Formyl-5,6,7,8-Tetrahydrofolate
DB03315 Guanosine-3'-Monophosphate
DB03419 Uracil
DB03435 Uridine-5'-Diphosphate
DB03471 6-Phenyl-4(R)-(7-Phenyl-Heptanoylamino)-Hexanoic Acid
DB03501 Uridine Diphosphate Galactose
DB03541 10-Propargyl-5,8-Dideazafolic Acid
DB03554 5-Iodouracil
DB03585 Oxyphenbutazone
DB03685 Uridine-5'-Monophosphate
DB03761 5-Fluoro-2'-Deoxyuridine-5'-Monophosphate
DB03784 Elaidoylamide
DB03798 2'-Deoxycytidine-5'-Monophosphate
DB03800 2'-deoxyuridylic acid
DB03814 2-(N-Morpholino)-Ethanesulfonic Acid
DB04077 Glycerol
DB04112 1-Octadecyl-2-Acetamido-2-Deoxy-Sn-Glycerol-3-Phosphoethylmethyl Sulfide
DB04287 (S)-5-(4-Benzyloxy-Phenyl)-4-(7-Phenyl-Heptanoylamino)-Pentanoic Acid
DB04743 Nimesulide
DB04786 Suramin
DB06860 2-(2-chloropyridin-4-yl)-4-methyl-1H-isoindole-1,3(2H)-dione
DB06987 2-(4-(2-HYDROXY-3-(ISOPROPYLAMINO)PROPOXY)PHENYL)ETHANAMIDE
DB07500 (2E)-1-[2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl]-3-(4-hydroxyphenyl)prop-2-en-1-one
DB07507 2-(4-hydroxybiphenyl-3-yl)-4-methyl-1H-isoindole-1,3(2H)-dione
DB07511 4-(4-methyl-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzonitrile
DB07950 1H-INDOL-3-YLACETIC ACID
DB07958 (2-CARBAMOYLMETHYL-5-PROPYL-OCTAHYDRO-INDOL-7-YL)ACETIC ACID
DB08204 3-DIPHENOL-6-NITRO-3H-BENZO[DE]ISOCHROMEN-1-ONE
DB08447 3-{3-[(DIMETHYLAMINO)METHYL]-1H-INDOL-7-YL}PROPAN-1-OL
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