DT-Web

DB01685 - 4-[5-Pyridin-4-Yl-1h-[1,2,4]Triazol-3-Yl]-Pyridine-2-Carbonitrile


Identification
Name 4-[5-Pyridin-4-Yl-1h-[1,2,4]Triazol-3-Yl]-Pyridine-2-Carbonitrile
Accession Number DB01685 (EXPT01517)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 248.2428
Groups experimental
Monoisotopic Weight 248.081044286
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Xanthine dehydrogenase/oxidase
Name Xanthine dehydrogenase/oxidase
Gene Name XDH
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.3973

Predictions


Id Partner name Gene Name Score
6020 Aldehyde oxidase AOX1 0.0337
1898 Cytochrome P450 1B1 CYP1B1 0.0267
6032 PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) fas 0.018
1405 Thiopurine S-methyltransferase TPMT 0.0172
87 Hypoxanthine-guanine phosphoribosyltransferase HPRT1 0.0171
63 Malate dehydrogenase mdh 0.0165
2329 Malate dehydrogenase mdh 0.0165
3445 Malate dehydrogenase mdh 0.0165
4420 Malate dehydrogenase mdh 0.0165
4438 Malate dehydrogenase mdh 0.0165
4512 Cytochrome P450 3A4 CYP3A4 0.0165
6142 Solute carrier family 22 member 8 SLC22A8 0.0164
896 Glutathione S-transferase Mu 1 GSTM1 0.0163
327 Glutathione reductase gor 0.0156
5110 Glutathione reductase GR2 0.0156
3823 Cytokine receptor common gamma chain IL2RG 0.0151
893 [Citrate [pro-3S]-lyase] ligase citC 0.0149
845 Pyruvate dehydrogenase [cytochrome] poxB 0.0149
4200 Cytochrome P450 1A2 CYP1A2 0.0141
290 Prostaglandin G/H synthase 2 PTGS2 0.0132
724 Interleukin-2 receptor alpha chain IL2RA 0.0131
717 Interleukin-2 receptor subunit beta IL2RB 0.0131
2157 NAD(P)H dehydrogenase [quinone] 1 NQO1 0.0118
303 Diamine acetyltransferase 2 SAT2 0.0109
623 Spermine oxidase SMOX 0.0109
1317 Spermine synthase SMS 0.0109
1656 CYP2B protein CYP2B 0.0108
6143 Solute carrier family 22 member 7 SLC22A7 0.0108
3932 Glutathione S-transferase A2 GSTA2 0.01
4031 Glutathione S-transferase A1 GSTA1 0.01
123 Diamine acetyltransferase 1 SAT1 0.01
1757 Myeloperoxidase MPO 0.0097
6859 Protein S100-A4 S100A4 0.0091
6161 Probable low affinity copper uptake protein 2 SLC31A2 0.0091
833 Organic cation/carnitine transporter 1 SLC22A4 0.0091
1588 Multidrug resistance protein 1 ABCB1 0.0086
6168 Solute carrier family 22 member 16 SLC22A16 0.0085
3923 Cholinesterase BCHE 0.0084
6163 Copper-transporting ATPase 2 ATP7B 0.0083
6165 Copper-transporting ATPase 1 ATP7A 0.0083
1735 Canalicular multispecific organic anion transporter 1 ABCC2 0.0081
1732 ATP-binding cassette sub-family G member 2 ABCG2 0.0081
6136 Multidrug resistance-associated protein 5 ABCC5 0.008
6146 High affinity copper uptake protein 1 SLC31A1 0.0079
6013 Cytochrome P450 2E1 CYP2E1 0.0079
449 Ornithine decarboxylase ODC1 0.0078
6137 Multidrug resistance-associated protein 6 ABCC6 0.0078
4152 Superoxide dismutase [Cu-Zn] SOD1 0.0077
908 Glutathione S-transferase theta-1 GSTT1 0.0076
723 Cytosolic phospholipase A2 PLA2G4A 0.0075
4119 Cytochrome P450 2D6 CYP2D6 0.0074
3811 Cytochrome P450 19A1 CYP19A1 0.0072
734 D1 dopamine receptor-interacting protein calcyon CALY 0.0072
6171 Solute carrier family 28 member 3 SLC28A3 0.0068
1561 Troponin C, slow skeletal and cardiac muscles TNNC1 0.0064
636 Mitochondrial carnitine/acylcarnitine carrier protein SLC25A20 0.0062
109 Mitochondrial carnitine/acylcarnitine carrier protein CACL SLC25A29 0.0062
2222 Equilibrative nucleoside transporter 1 SLC29A1 0.0062
4120 NADPH--cytochrome P450 reductase POR 0.0061
904 Glutathione S-transferase P GSTP1 0.0061
6024 Cytochrome P450 1A1 CYP1A1 0.006
556 Alpha-1A adrenergic receptor ADRA1A 0.0059
6025 UDP-glucuronosyltransferase 1-4 UGT1A4 0.0057
551 Carnitine O-acetyltransferase CRAT 0.0054
451 Carnitine O-palmitoyltransferase I, liver isoform CPT1A 0.0054
200 Carnitine O-palmitoyltransferase 2, mitochondrial CPT2 0.0054
412 Peroxisomal carnitine O-octanoyltransferase CROT 0.0054
1374 Natriuretic peptides B NPPB 0.0051
1827 Gap junction alpha-1 protein GJA1 0.0051
1908 Vascular cell adhesion protein 1 VCAM1 0.0051
400 Coagulation factor IX F9 0.005
5461 Coagulation factor IX F9 0.005
6148 Multidrug resistance-associated protein 7 ABCC10 0.005
465 Calmodulin CALM1 0.0049
194 NADH dehydrogenase [ubiquinone] 1 subunit C2 NDUFC2 0.0049
6145 Solute carrier family 22 member 1 SLC22A1 0.0048
2164 Multidrug resistance-associated protein 4 ABCC4 0.0048
817 DNA topoisomerase 2-alpha TOP2A 0.0047
4081 Vitamin K epoxide reductase complex subunit 1-like protein 1 VKORC1L1 0.0046
604 Vitamin K-dependent protein Z PROZ 0.0046
422 Vitamin K-dependent protein C PROC 0.0042
1245 Vitamin K-dependent protein S PROS1 0.0042
776 Bile salt export pump ABCB11 0.0042
6144 Solute carrier family 22 member 2 SLC22A2 0.0041
243 Ribosyldihydronicotinamide dehydrogenase [quinone] NQO2 0.004
4192 DNA topoisomerase 2-beta TOP2B 0.0039
183 Vascular endothelial growth factor A VEGFA 0.0039
831 D(2) dopamine receptor DRD2 0.0039
862 Multidrug resistance-associated protein 1 ABCC1 0.0039
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0037
1709 Canalicular multispecific organic anion transporter 2 ABCC3 0.0037
4604 Liver carboxylesterase 1 CES1 0.0035
798 Osteocalcin BGLAP 0.0035
214 NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial NDUFS3 0.0035
337 NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial NDUFS7 0.0035
803 NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial NDUFS2 0.0035
6172 ATP-binding cassette sub-family B member 8, mitochondrial ABCB8 0.0034
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.0033
369 Coagulation factor VII F7 0.0032
787 Vitamin K epoxide reductase complex subunit 1 VKORC1 0.0031
4757 Cytochrome P450 2C9 CYP2C9 0.0029
118 Organic cation/carnitine transporter 2 SLC22A5 0.0029
3917 Methylenetetrahydrofolate reductase MTHFR 0.0029
1490 Solute carrier organic anion transporter family member 1B1 SLCO1B1 0.0029
468 Cytochrome P450 4A11 CYP4A11 0.0028
6030 Cytochrome P450 2B6 CYP2B6 0.0028
101 Potassium voltage-gated channel subfamily H member 2 KCNH2 0.0027
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0026
76 Nitric-oxide synthase, brain NOS1 0.0026
193 Beta-1 adrenergic receptor ADRB1 0.0024
239 Coagulation factor X F10 0.0024
766 Beta-2 adrenergic receptor ADRB2 0.0024
5251 Carbonyl reductase [NADPH] 1 CBR1 0.0023
20 Prostaglandin G/H synthase 1 PTGS1 0.002
54 Prothrombin F2 0.002
5718 Cytochrome P450 2A6 CYP2A6 0.0019
4118 Cytochrome P450 3A5 CYP3A5 0.0019
7 Nitric oxide synthase, inducible NOS2 0.0017
291 Nitric-oxide synthase, endothelial NOS3 0.0017
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0017
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0017
839 Short-chain specific acyl-CoA dehydrogenase, mitochondrial ACADS 0.0015
4486 Phenol 2-hydroxylase component B pheA2 0.0013
4439 Ferredoxin reductase bphA4 0.0013
4477 Dihydrolipoyl dehydrogenase lpdV 0.0013
5077 Dihydrolipoyl dehydrogenase Not Available 0.0013
5117 Dihydrolipoyl dehydrogenase lpd 0.0013
5078 Amine oxidase, flavin-containing PSPTO1126 0.0012
5122 Mersacidin decarboxylase mrsD 0.0012
526 Thioredoxin reductase trxB 0.0012
3767 Thioredoxin reductase trxB 0.0012
5112 Benzoate 1,2-dioxygenase electron transfer component benC 0.0012
3763 5,10-methylenetetrahydrofolate reductase metF 0.0012
3918 5,10-methylenetetrahydrofolate reductase MTHFR 0.0012
5094 5,10-methylenetetrahydrofolate reductase metF 0.0012
5097 PROBABLE DIHYDROLIPOAMIDE DEHYDROGENASE LPDA lpdA 0.0012
5102 4-cresol dehydrogenase [hydroxylating] flavoprotein subunit pchF 0.0012
5115 FkbI fkbI 0.0012
3133 UDP-galactopyranose mutase glf 0.0012
5099 UDP-galactopyranose mutase glf 0.0012
5114 Putative acyl-CoA dehydrogenase TT_C0779 0.0012
5095 Putidaredoxin reductase camA 0.0012
5083 Cryptochrome DASH cry 0.0012
5100 Gamma-aminobutyrate metabolism dehydratase/isomerase abfD 0.0012
5107 Alkyl hydroperoxide reductase subunit F ahpF 0.0012
5118 Alkyl hydroperoxide reductase subunit F ahpF 0.0012
5081 L-aspartate oxidase nadB 0.0012
5111 Phenylacetone monooxygenase pamO 0.0012
1410 Oxidoreductase HSD17B6 0.0012
4725 Oxidoreductase Not Available 0.0012
5124 Oxidoreductase Not Available 0.0012
5109 Outer membrane protein p64k or PM-6 m-6 0.0012
1329 Apoptosis-inducing factor 1, mitochondrial AIFM1 0.0012
714 Glutathione reductase, mitochondrial GSR 0.0011
3102 Flavohemoprotein hmp 0.0011
4969 Flavohemoprotein hmp 0.0011
4440 NADH peroxidase npr 0.0011
5072 N,N-dimethylglycine oxidase dmg 0.0011
5073 Ferredoxin--NADP reductase petH 0.0011
5076 Ferredoxin--NADP reductase fpr 0.0011
5119 Ferredoxin--NADP reductase petH 0.0011
5121 Ferredoxin--NADP reductase fpr 0.0011
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0011
3594 Deoxyribodipyrimidine photo-lyase phr 0.0011
5079 Deoxyribodipyrimidine photo-lyase phrB 0.0011
5080 Deoxyribodipyrimidine photo-lyase phr 0.0011
440 Isovaleryl-CoA dehydrogenase, mitochondrial IVD 0.0011
5003 Acyl-CoA dehydrogenase, short-chain specific Not Available 0.0011
2526 NADPH-ferredoxin reductase fprA fprA 0.0011
667 Acyl-CoA dehydrogenase family member 8, mitochondrial ACAD8 0.0011
5091 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0011
5093 UDP-N-acetylenolpyruvoylglucosamine reductase murB 0.0011
3506 Glutaryl-CoA dehydrogenase, mitochondrial GCDH 0.0011
2470 Pyruvate oxidase pox5 0.0011
6639 Peroxisomal acyl-coenzyme A oxidase 1 ACOX1 0.0011
3247 2-oxopropyl-CoM reductase, carboxylating xecC 0.001
2268 Cholesterol oxidase choB 0.001
2822 Cholesterol oxidase choA 0.001
126 D-lactate dehydrogenase dld 0.001
3545 D-lactate dehydrogenase Not Available 0.001
4510 D-lactate dehydrogenase ldhA 0.001
605 Fumarate reductase flavoprotein subunit frdA 0.001
2709 Fumarate reductase flavoprotein subunit SO_0970 0.001
3673 Fumarate reductase flavoprotein subunit fccA 0.001
4912 Fumarate reductase flavoprotein subunit ifcA 0.001
6549 Fumarate reductase flavoprotein subunit frdA 0.001
3185 Medium-chain specific acyl-CoA dehydrogenase, mitochondrial ACADM 0.001
3254 Bifunctional protein putA [Includes: Proline dehydrogenase putA 0.001
2893 Glycine oxidase thiO 0.001
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0009
2567 Thymidylate synthase thyX thyX 0.0009
2823 Trypanothione reductase TPR 0.0009
2769 P-hydroxybenzoate hydroxylase pobA 0.0009
2809 P-hydroxybenzoate hydroxylase pobA 0.0009
3610 Thioredoxin reductase 1, cytoplasmic TXNRD1 0.0009
2380 Monomeric sarcosine oxidase soxA 0.0008
6645 D-amino-acid oxidase DAO 0.0008
1302 Dihydropyrimidine dehydrogenase [NADP+] DPYD 0.0008
816 Biliverdin reductase A BLVRA 0.0007
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0007
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0007
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0007
30 NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial NDUFV3 0.0006
374 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 NDUFB1 0.0006
247 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 NDUFA1 0.0006
343 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial NDUFC1 0.0006
190 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 NDUFA4 0.0006
353 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 NDUFA4L2 0.0006
607 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 NDUFA2 0.0006
324 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 NDUFB4 0.0006
598 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 NDUFA11 0.0006
405 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 NDUFA8 0.0006
555 NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial NDUFS4 0.0006
446 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 NDUFA7 0.0006
656 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 NDUFB9 0.0006
525 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 NDUFA5 0.0006
219 NADH-ubiquinone oxidoreductase chain 3 MT-ND3 0.0006
104 NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial NDUFS6 0.0006
236 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 NDUFA6 0.0006
417 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 NDUFB6 0.0006
475 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial NDUFB2 0.0006
582 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 NDUFA13 0.0006
829 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 NDUFA12 0.0006
755 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 NDUFA3 0.0006
487 Aldo-keto reductase family 1 member C4 AKR1C4 0.0006
313 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 NDUFB3 0.0006
384 NADH-ubiquinone oxidoreductase chain 6 MT-ND6 0.0006
300 NADH-ubiquinone oxidoreductase chain 4L MT-ND4L 0.0006
746 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial NDUFB8 0.0006
99 NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 NDUFS5 0.0006
270 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial NDUFB5 0.0006
644 Heme oxygenase 2 HMOX2 0.0006
4982 Heme oxygenase 2 pbsA2 0.0006
41 NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial NDUFS8 0.0006
335 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial NDUFA9 0.0006
568 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 NDUFB7 0.0006
616 Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial IDH3B 0.0006
152 NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial NDUFV2 0.0006
848 Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial IDH3G 0.0006
145 Corticosteroid 11-beta-dehydrogenase isozyme 2 HSD11B2 0.0006
609 15-hydroxyprostaglandin dehydrogenase [NAD+] HPGD 0.0006
602 Acyl carrier protein, mitochondrial NDUFAB1 0.0006
539 NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial NDUFV1 0.0006
272 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 NDUFB10 0.0006
372 Estradiol 17-beta-dehydrogenase 3 HSD17B3 0.0006
729 GDP-L-fucose synthetase TSTA3 0.0006
3463 GDP-L-fucose synthetase fcl 0.0006
167 L-lactate dehydrogenase C chain LDHC 0.0006
326 L-lactate dehydrogenase A-like 6A LDHAL6A 0.0006
141 3-hydroxyisobutyrate dehydrogenase, mitochondrial HIBADH 0.0006
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0006
3726 D-3-phosphoglycerate dehydrogenase serA 0.0006
4291 D-3-phosphoglycerate dehydrogenase serA 0.0006
206 3-keto-steroid reductase HSD17B7 0.0006
196 D-beta-hydroxybutyrate dehydrogenase, mitochondrial BDH1 0.0006
721 NADH-ubiquinone oxidoreductase chain 2 MT-ND2 0.0006
231 Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmic GPD1 0.0006
91 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial NDUFA10 0.0006
14 Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial IDH3A 0.0006
50 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating NSDHL 0.0006
112 L-lactate dehydrogenase A-like 6B LDHAL6B 0.0006
216 Aldehyde dehydrogenase 3B2 ALDH3B2 0.0006
637 NADH-ubiquinone oxidoreductase chain 5 MT-ND5 0.0006
9 Estradiol 17-beta-dehydrogenase 2 HSD17B2 0.0006
671 Pyruvate dehydrogenase E1 component alpha subunit, testis-specific form, mitochondrial PDHA2 0.0006
628 Pyruvate dehydrogenase E1 component alpha subunit, somatic form, mitochondrial PDHA1 0.0006
149 Alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 0.0006
608 NADH-ubiquinone oxidoreductase chain 4 MT-ND4 0.0006
496 Aldehyde dehydrogenase 3B1 ALDH3B1 0.0006
34 7-dehydrocholesterol reductase DHCR7 0.0006
662 Fatty aldehyde dehydrogenase ALDH3A2 0.0006
711 UDP-glucose 6-dehydrogenase UGDH 0.0006
3672 UDP-glucose 6-dehydrogenase hasB 0.0006
393 GDH/6PGL endoplasmic bifunctional protein [Includes: Glucose 1-dehydrogenase H6PD 0.0006
531 Aldehyde dehydrogenase X, mitochondrial ALDH1B1 0.0006
107 C-4 methylsterol oxidase SC4MOL 0.0006
258 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial ALDH6A1 0.0006
271 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial ALDH4A1 0.0006
288 Trifunctional enzyme subunit alpha, mitochondrial HADHA 0.0006
643 Peroxisomal bifunctional enzyme EHHADH 0.0006
548 NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial NDUFS1 0.0006
646 Malate dehydrogenase, cytoplasmic MDH1 0.0006
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0006
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0006
328 Sorbitol dehydrogenase SORD 0.0006
396 Alcohol dehydrogenase 4 ADH4 0.0006
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0006
597 Dihydropteridine reductase QDPR 0.0006
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0006
3939 Amine oxidase [flavin-containing] B MAOB 0.0006
3941 Amine oxidase [flavin-containing] A MAOA 0.0006
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0006
666 NADP-dependent malic enzyme ME1 0.0006
857 Malate dehydrogenase, mitochondrial MDH2 0.0005
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0005
77 L-lactate dehydrogenase B chain LDHB 0.0005
12 Alcohol dehydrogenase class 3 ADH5 0.0005
296 Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial MTHFD2 0.0005
6026 Alcohol dehydrogenase 6 ADH6 0.0005
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.0005
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.0005
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0005
182 2-oxoglutarate dehydrogenase E1 component, mitochondrial OGDH 0.0005
110 Pyruvate dehydrogenase E1 component subunit beta, mitochondrial PDHB 0.0005
626 Cysteine dioxygenase type 1 CDO1 0.0005
627 11-cis retinol dehydrogenase RDH5 0.0005
640 Aldehyde dehydrogenase 1A3 ALDH1A3 0.0005
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.0005
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0005
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0005
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.0005
473 L-lactate dehydrogenase A chain LDHA 0.0005
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.0005
66 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II HSD3B2 0.0005
569 Retinal dehydrogenase 2 ALDH1A2 0.0005
74 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial DLAT 0.0005
13 Aminomethyltransferase, mitochondrial AMT 0.0005
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0005
611 Retinal dehydrogenase 1 ALDH1A1 0.0005
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0005
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0005
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0005
57 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type I HSD3B1 0.0005
251 Alcohol dehydrogenase 1A ADH1A 0.0005
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0005
279 Tyrosinase TYR 0.0005
170 Succinate semialdehyde dehydrogenase, mitochondrial ALDH5A1 0.0004
838 Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 0.0004
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0004
654 Flavin reductase BLVRB 0.0004
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0004
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.0004
810 Heme oxygenase 1 HMOX1 0.0004
3391 Heme oxygenase 1 pbsA1 0.0004
444 Alcohol dehydrogenase 1B ADH1B 0.0004
380 Cytochrome P450 17A1 CYP17A1 0.0004
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.0004
559 NADH-ubiquinone oxidoreductase chain 1 MT-ND1 0.0004
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0004
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0004
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0004
517 Alcohol dehydrogenase 1C ADH1C 0.0004
822 Aldose reductase AKR1B1 0.0003
365 Dihydrofolate reductase DHFR 0.0003
2381 Dihydrofolate reductase DFR1 0.0003
2833 Dihydrofolate reductase Not Available 0.0003
2931 Dihydrofolate reductase folA 0.0003
3544 Dihydrofolate reductase folA 0.0003
3682 Dihydrofolate reductase folA 0.0003
6642 Dihydrofolate reductase folA 0.0003
6756 Dihydrofolate reductase dfrA 0.0003
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