DT-Web

DB08605 - 6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL


Identification
Name 6-METHYL-2(PROPANE-1-SULFONYL)-2H-THIENO[3,2-D][1,2,3]DIAZABORININ-1-OL
Accession Number DB08605
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 272.152
Groups experimental
Monoisotopic Weight 272.046064138
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


2,4-dienoyl-CoA reductase, mitochondrial
Name 2,4-dienoyl-CoA reductase, mitochondrial
Gene Name DECR1
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.4836
Enoyl-[acyl-carrier-protein] reductase [NADH]
Name Enoyl-[acyl-carrier-protein] reductase [NADH]
Gene Name fabI
Pharmacological action unknown
Actions Not Available
References
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.0819

Predictions


Id Partner name Gene Name Score
6855 Enoyl-(Acyl-carrier-protein) reductase fabI 0.1391
6877 Enoyl-(Acyl-carrier-protein) reductase fabK 0.1391
368 Enoyl-[acyl-carrier-protein] reductase [NADH] inhA 0.0819
3228 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0819
6856 Enoyl-[acyl-carrier-protein] reductase [NADH] fabI 0.0819
4484 2,5-diketo-D-gluconic acid reductase A dkgA 0.0135
646 Malate dehydrogenase, cytoplasmic MDH1 0.0114
6861 Alcohol dehydrogenase [NADP+] AKR1A1 0.01
5326 Oxidoreductase, short chain dehydrogenase/reductase family TM_0441 0.0097
3772 3-oxoacyl-[acyl-carrier-protein] reductase fabG 0.0097
5157 Dehydrogenase/reductase SDR family member 11 DHRS11 0.0097
3778 NAD(P) transhydrogenase subunit beta pntB 0.0097
5322 Oxidoreductase ydhF ydhF 0.0097
4403 Protein iolS iolS 0.0097
5330 General stress protein 69 yhdN 0.0097
5346 Oxidoreductase, aldo/keto reductase family TM_1009 0.0097
5342 NADH-dependent butanol dehydrogenase, putative TM_0820 0.0097
5332 MtdA bifunctional protein mtdA 0.0097
5333 Alcohol dehydrogenase, iron-containing TM_0920 0.0097
5343 NADP-dependent fatty aldehyde dehydrogenase aldH 0.0097
217 Estradiol 17-beta-dehydrogenase 1 HSD17B1 0.009
444 Alcohol dehydrogenase 1B ADH1B 0.009
989 L-xylulose reductase DCXR 0.0084
2636 Shikimate dehydrogenase aroE 0.0084
3515 Shikimate dehydrogenase aroE 0.0084
5328 Prostaglandin F synthase Tb11.02.2310 0.0084
4582 Putative pteridine reductase 2 ptr2 0.0084
2375 ADP-L-glycero-D-manno-heptose-6-epimerase hldD 0.0084
5073 Ferredoxin--NADP reductase petH 0.0084
5076 Ferredoxin--NADP reductase fpr 0.0084
5119 Ferredoxin--NADP reductase petH 0.0084
5121 Ferredoxin--NADP reductase fpr 0.0084
3446 NADP-dependent alcohol dehydrogenase adh 0.0084
5075 Sulfite reductase [NADPH] flavoprotein alpha-component cysJ 0.0084
2305 Isocitrate dehydrogenase [NADP] cytoplasmic IDH1 0.0084
4628 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase gapN 0.0084
1799 Glucose-6-phosphate 1-dehydrogenase G6PD 0.0084
2630 Glucose-6-phosphate 1-dehydrogenase zwf 0.0084
729 GDP-L-fucose synthetase TSTA3 0.0084
3463 GDP-L-fucose synthetase fcl 0.0084
2286 Isocitrate dehydrogenase [NADP] icd 0.0084
2302 Isocitrate dehydrogenase [NADP] icd 0.0084
2771 Isocitrate dehydrogenase [NADP] icd 0.0084
4509 Acetoin(diacetyl) reductase budC 0.0079
4531 Putative ketoacyl reductase actIII 0.0078
6297 Prostaglandin reductase 1 PTGR1 0.0078
3062 Aspartate-semialdehyde dehydrogenase asd 0.0078
6862 Aldo-keto reductase family 1 member B10 AKR1B10 0.0078
635 Estradiol 17-beta-dehydrogenase 8 HSD17B8 0.0074
666 NADP-dependent malic enzyme ME1 0.0074
1124 Sepiapterin reductase SPR 0.0073
2675 Pteridine reductase 1 PTR1 0.0073
3573 2,4-dienoyl-CoA reductase [NADPH] fadH 0.0073
2159 Quinone oxidoreductase CRYZ 0.0073
11 NAD(P) transhydrogenase, mitochondrial NNT 0.0071
2826 Glucose--fructose oxidoreductase gfo 0.0069
686 Aldo-keto reductase family 1 member C2 AKR1C2 0.0064
679 C-1-tetrahydrofolate synthase, cytoplasmic MTHFD1 0.0063
654 Flavin reductase BLVRB 0.0061
4423 Levodione reductase lvr 0.0059
4435 L-aspartate dehydrogenase nadX 0.0059
4495 3-oxoacyl-(Acyl carrier protein) reductase TM_1169 0.0059
4428 Redox-sensing transcriptional repressor rex rex 0.0059
4472 Glucose 1-dehydrogenase Not Available 0.0059
4448 L-2-hydroxyisocaproate dehydrogenase Not Available 0.0059
4447 Hypothetical protein yhfP yhfP 0.0059
4507 Alanine dehydrogenase ald 0.0059
4505 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase bphB 0.0059
2350 3-isopropylmalate dehydrogenase leuB 0.0059
3092 3-isopropylmalate dehydrogenase leuB 0.0059
4449 ADP-ribosyltransferase Not Available 0.0059
4456 Inorganic polyphosphate/ATP-NAD kinase ppnK 0.0059
4455 Glycerol dehydrogenase gldA 0.0059
4336 Glyceraldehyde 3-phosphate dehydrogenase Not Available 0.0059
4436 Glyceraldehyde 3-phosphate dehydrogenase tthHB8IM 0.0059
4418 AGR_L_3209p AGR_L_3209 0.0059
4446 3alpha-hydroxysteroid dehydrogenase/carbonyl reductase Not Available 0.0059
4497 Benzyl alcohol dehydrogenase xylB 0.0059
139 Aldo-keto reductase family 1 member C1 AKR1C1 0.0059
4414 Dehydrogenase TT_P0035 0.0059
3735 NAD(P) transhydrogenase subunit alpha part 1 pntAA 0.0059
3729 Citrate synthase gltA 0.0059
4575 Citrate synthase cit 0.0059
4580 Citrate synthase gltA 0.0059
4475 Hypothetical protein Rv0046c/MT0052 ino1 0.0059
4500 L-lactate dehydrogenase 2 ldh2 0.0059
4506 Myo-inositol-1-phosphate synthase-related protein TM_1419 0.0059
4451 Vip2Ac vip2Ac 0.0059
4471 CDP-D-glucose-4,6-dehydratase ascB 0.0059
4443 Quinate/shikimate dehydrogenase ydiB 0.0059
180 D-3-phosphoglycerate dehydrogenase PHGDH 0.0059
3726 D-3-phosphoglycerate dehydrogenase serA 0.0059
4291 D-3-phosphoglycerate dehydrogenase serA 0.0059
4467 Alpha-glucosidase, putative TM_0752 0.0059
3381 Alcohol dehydrogenase Not Available 0.0059
4508 Alcohol dehydrogenase adhA 0.0059
4466 Glutathione-independent formaldehyde dehydrogenase fdhA 0.0059
4502 Formate dehydrogenase Not Available 0.0059
4487 Transcriptional regulator nadR nadR 0.0059
650 Aldo-keto reductase family 1 member C3 AKR1C3 0.0055
364 Corticosteroid 11-beta-dehydrogenase isozyme 1 HSD11B1 0.0053
4486 Phenol 2-hydroxylase component B pheA2 0.0051
3671 7-alpha-hydroxysteroid dehydrogenase hdhA 0.0051
2831 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase Not Available 0.0051
3059 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase fabG3 0.0051
3087 Nicotinate-nucleotide adenylyltransferase nadD 0.0051
4469 Nicotinate-nucleotide adenylyltransferase nadD 0.0051
6698 Dehydrogenase/reductase SDR family member 4-like 2 DHRS4L2 0.0051
4503 NADPH-flavin oxidoreductase frp 0.0051
3615 Dihydrodipicolinate reductase dapB 0.0051
3618 Dihydrodipicolinate reductase dapB 0.0051
4462 Dihydrodipicolinate reductase dapB 0.0051
4427 TDP-glucose-4,6-dehydratase desIV 0.0051
2336 2,3-diketo-L-gulonate reductase dlgD 0.0051
1199 GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 ART1 0.0051
2967 CDP-paratose 2-epimerase rfbE 0.0051
3401 D-2-hydroxyisocaproate dehydrogenase Not Available 0.0051
3598 dTDP-4-dehydrorhamnose reductase rfbD 0.0051
2424 L-lactate dehydrogenase ldh 0.0051
2641 L-lactate dehydrogenase Not Available 0.0051
4437 L-lactate dehydrogenase ldh 0.0051
4442 L-lactate dehydrogenase ldh 0.0051
4450 Iota toxin component Ia Not Available 0.0051
4482 UDP-galactose 4-epimerase galE 0.0051
126 D-lactate dehydrogenase dld 0.0051
3545 D-lactate dehydrogenase Not Available 0.0051
4510 D-lactate dehydrogenase ldhA 0.0051
4439 Ferredoxin reductase bphA4 0.0051
4498 Ornithine cyclodeaminase PP3533 0.0051
2538 6-phospho-beta-glucosidase bglT bglT 0.0051
3177 dTDP-glucose 4,6-dehydratase rfbB 0.0051
4499 dTDP-glucose 4,6-dehydratase rmlB 0.0051
2018 Deoxyhypusine synthase DHPS 0.0051
2393 Maltose-6'-phosphate glucosidase glvA 0.0051
4477 Dihydrolipoyl dehydrogenase lpdV 0.0051
5077 Dihydrolipoyl dehydrogenase Not Available 0.0051
5117 Dihydrolipoyl dehydrogenase lpd 0.0051
2881 Gamma-aminobutyraldehyde dehydrogenase prr 0.0051
3081 3-dehydroquinate synthase aroB 0.0051
4496 C-terminal-binding protein 1 CTBP1 0.0051
2507 Diphtheria toxin Not Available 0.0051
2591 Urocanate hydratase hutU 0.0051
76 Nitric-oxide synthase, brain NOS1 0.0049
822 Aldose reductase AKR1B1 0.0049
631 3-hydroxy-3-methylglutaryl-coenzyme A reductase HMGCR 0.0048
3387 3-hydroxy-3-methylglutaryl-coenzyme A reductase mvaA 0.0048
4120 NADPH--cytochrome P450 reductase POR 0.0048
2683 Mono-ADP-ribosyltransferase C3 C3 0.0047
3296 Nicotinamide mononucleotide adenylyltransferase 1 NMNAT1 0.0047
4440 NADH peroxidase npr 0.0047
3736 Glyceraldehyde-3-phosphate dehydrogenase A gapA 0.0047
2799 Glyceraldehyde-3-phosphate dehydrogenase, glycosomal Not Available 0.0047
3367 GDP-mannose 6-dehydrogenase algD 0.0047
4318 Siroheme synthase cysG 0.0047
4504 WbpP Not Available 0.0047
4343 Alpha-glucosidase aglA 0.0047
711 UDP-glucose 6-dehydrogenase UGDH 0.0047
3672 UDP-glucose 6-dehydrogenase hasB 0.0047
365 Dihydrofolate reductase DHFR 0.0046
2381 Dihydrofolate reductase DFR1 0.0046
2833 Dihydrofolate reductase Not Available 0.0046
2931 Dihydrofolate reductase folA 0.0046
3544 Dihydrofolate reductase folA 0.0046
3682 Dihydrofolate reductase folA 0.0046
6642 Dihydrofolate reductase folA 0.0046
6756 Dihydrofolate reductase dfrA 0.0046
3333 Nicotinamide mononucleotide adenylyltransferase 3 NMNAT3 0.0044
2434 NH(3)-dependent NAD(+) synthetase nadE 0.0044
2910 NH(3)-dependent NAD(+) synthetase nadE 0.0044
3217 NH(3)-dependent NAD(+) synthetase nadE 0.0044
2617 Nitric oxide synthase oxygenase nos 0.0044
2701 Nitric oxide synthase oxygenase nos 0.0044
3070 Adenosylhomocysteinase AHCY 0.0044
4424 Adenosylhomocysteinase PFE1050w 0.0044
6278 Adenosylhomocysteinase ahcY 0.0044
3191 Histidinol dehydrogenase hisD 0.0044
816 Biliverdin reductase A BLVRA 0.0044
792 Aldehyde dehydrogenase, dimeric NADP-preferring ALDH3A1 0.0044
316 4-trimethylaminobutyraldehyde dehydrogenase ALDH9A1 0.0044
579 Alcohol dehydrogenase class 4 mu/sigma chain ADH7 0.0044
63 Malate dehydrogenase mdh 0.0043
2329 Malate dehydrogenase mdh 0.0043
3445 Malate dehydrogenase mdh 0.0043
4420 Malate dehydrogenase mdh 0.0043
4438 Malate dehydrogenase mdh 0.0043
4476 Mannitol dehydrogenase mtlD 0.0043
350 3-hydroxyacyl-CoA dehydrogenase type-2 HSD17B10 0.0043
597 Dihydropteridine reductase QDPR 0.0043
178 NADH-cytochrome b5 reductase 3 CYB5R3 0.0043
812 Dihydrolipoyl dehydrogenase, mitochondrial DLD 0.0043
328 Sorbitol dehydrogenase SORD 0.0043
396 Alcohol dehydrogenase 4 ADH4 0.0043
363 NADP-dependent malic enzyme, mitochondrial ME3 0.0043
454 Peroxisomal multifunctional enzyme type 2 HSD17B4 0.0043
5766 NAD-dependent deacetylase sirtuin-5 SIRT5 0.0042
327 Glutathione reductase gor 0.0042
5110 Glutathione reductase GR2 0.0042
419 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial HADH 0.0041
77 L-lactate dehydrogenase B chain LDHB 0.0041
12 Alcohol dehydrogenase class 3 ADH5 0.0041
4491 DNA ligase, NAD-dependent ligA 0.0041
473 L-lactate dehydrogenase A chain LDHA 0.004
599 Glyceraldehyde-3-phosphate dehydrogenase GAPDH 0.004
4426 Glyceraldehyde-3-phosphate dehydrogenase gap 0.004
4454 Glyceraldehyde-3-phosphate dehydrogenase gap 0.004
4489 Glyceraldehyde-3-phosphate dehydrogenase gap 0.004
794 Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GAPDHS 0.004
2762 UDP-glucose 4-epimerase GALE 0.004
3461 UDP-glucose 4-epimerase galE 0.004
166 NAD-dependent malic enzyme, mitochondrial ME2 0.0039
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0038
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0035
251 Alcohol dehydrogenase 1A ADH1A 0.0035
611 Retinal dehydrogenase 1 ALDH1A1 0.0035
796 Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 0.0034
569 Retinal dehydrogenase 2 ALDH1A2 0.0034
3689 Endoglucanase A celA 0.0033
5411 Slt-IIvB stxB2e 0.0033
5563 Galectin-2 LGALS2 0.0033
5565 Inorganic polyphosphate/ATP-glucomannokinase ppgmk 0.0033
5046 Ecotin eco 0.0033
5554 D-galactose-binding periplasmic protein mglB 0.0033
3741 D-galactose-binding periplasmic protein precursor mglB 0.0033
4668 Laminarinase TM_0024 0.0033
1875 Pulmonary surfactant-associated protein D SFTPD 0.0033
3009 Beta-glucanase Not Available 0.0033
5562 Hexokinase Not Available 0.0033
3793 Aspartate ammonia-lyase aspA 0.0033
4670 Cellulase B celB 0.0033
5569 Endo-1,4-beta glucanase EngF engF 0.0033
5553 Endoglucanase E1 Acel_0614 0.0033
5568 Endoglucanase C307 celC307 0.0033
5570 Endoglucanase E-4 celD 0.0033
4667 BH0236 protein BH0236 0.0033
5559 Neopullulanase nplT 0.0033
4671 Endoglucanase C cenC 0.0033
3744 Endoglucanase SS precursor celS 0.0033
714 Glutathione reductase, mitochondrial GSR 0.0032
517 Alcohol dehydrogenase 1C ADH1C 0.0031
147 Aldehyde dehydrogenase, mitochondrial ALDH2 0.003
3525 ADP-ribose pyrophosphatase, mitochondrial NUDT9 0.0028
1503 Galectin-7 LGALS7 0.0028
1184 Interferon beta IFNB1 0.0028
5416 Coat protein VP1 Not Available 0.0028
5176 YtnJ moxC 0.0028
5498 Maltoporin lamB 0.0028
5561 Maltoporin lamB 0.0028
4622 Amylase Not Available 0.0028
5247 Endo-1,4-beta-xylanase Not Available 0.0028
5248 Endo-1,4-beta-xylanase xlnA 0.0028
5250 Endo-1,4-beta-xylanase xyl 0.0028
5056 Maltooligosyltrehalose trehalohydrolase, putative treZ 0.0028
4669 Endo-1,4-beta-xylanase A xynA 0.0028
4715 Endo-1,4-beta-xylanase A xlnA 0.0028
5560 Endo-1,4-beta-xylanase A xynA 0.0028
2705 Dimethyl sulfoxide reductase dmsA 0.0028
2728 Glucan 1,4-alpha-maltotetraohydrolase amyP 0.0028
3547 Enterotoxin type B entB 0.0026
2856 Glucosamine-6-phosphate isomerase GNPDA1 0.0026
3747 Cellulase B precursor celB 0.0026
3153 Quinoprotein glucose dehydrogenase-B gdhB 0.0026
2564 Glucan 1,4-alpha-maltohexaosidase Not Available 0.0026
4811 Amylosucrase ams 0.0026
2531 Alpha-amylase amyE 0.0026
2948 Alpha-amylase amy 0.0026
3169 Alpha-amylase Not Available 0.0026
2541 Neopullulanase 1 tvaI 0.0026
4819 Hydrolase Not Available 0.0026
5249 Hydrolase Not Available 0.0026
5436 Hydrolase Not Available 0.0026
3091 Maltodextrin phosphorylase malP 0.0026
2606 Neopullulanase 2 tvaII 0.0026
2324 Botulinum neurotoxin type B botB 0.0026
3225 Shiga toxin B-chain stxB 0.0025
4666 Fucose-binding lectin PA-IIL lecB 0.0025
4830 Aldose 1-epimerase galM 0.0025
3365 Beta-amylase spoII 0.0025
1881 Hexokinase-1 HK1 0.0025
2372 Bifunctional tail protein 9 0.0025
3030 Salivary alpha-amylase AMY1A 0.0024
6614 Lactase-like protein LCTL 0.0024
2293 Cyclomaltodextrin glucanotransferase Not Available 0.0024
2508 Cyclomaltodextrin glucanotransferase cgt 0.0024
2523 Cyclomaltodextrin glucanotransferase cgt 0.0024
3207 Cyclomaltodextrin glucanotransferase amyA 0.0024
1675 Glucokinase GCK 0.0024
4662 Glucokinase glk 0.0024
4692 A/G-specific adenine glycosylase mutY 0.0023
3668 Maltose-binding periplasmic protein precursor malE 0.0023
2802 Endoglucanase G celCCG 0.0023
2448 Exoglucanase/xylanase [Includes: Exoglucanase cex 0.0023
2570 Tetanus toxin tetX 0.0023
4272 POSSIBLE CELLULASE CELA1 celA1 0.0022
2440 Endoglucanase F celCCF 0.0021
2430 Chondroitinase B cslB 0.0021
2245 Xylose isomerase xylA 0.002
2253 Xylose isomerase xylA 0.002
2260 Xylose isomerase xylA 0.002
2431 Xylose isomerase xylA 0.002
2252 Endoglucanase 5A cel5A 0.0019
2723 Cholera enterotoxin subunit B ctxB 0.0019
10 Glycogen phosphorylase, liver form PYGL 0.0018
2427 Ferrichrome-iron receptor fhuA 0.0018
4513 Pancreatic alpha-amylase AMY2A 0.0018
1152 Glycogen phosphorylase, muscle form PYGM 0.0015
20 Prostaglandin G/H synthase 1 PTGS1 0.001
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