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Peptidyl-prolyl cis-trans isomerase, mitochondrial


Partner ID 2554
Name Peptidyl-prolyl cis-trans isomerase, mitochondrial
Synonyms 4446
Gene name PPIF
General function Posttranslational modification, protein turnover, chaperones
Specific function PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Gene sequence + ...

ATGCTGGCGCTGCGCTGCGGCTCCCGCTGGCTCGGCCTGCTCTCCGTCCCGCGCTCCGTGCCGCTGCGCCTCCCCGCGGCCCGCGCCTGCAGCAAGGGCTCCGGCGACCCGTCCTCTTCCTCCTCCTCCGGGAACCCGCTCGTGTACCTGGACGTGGACGCCAACGGGAAGCCGCTCGGCCGCGTGGTGCTGGAGCTGAAGGCAGATGTCGTCCCAAAGACAGCTGAGAACTTCAGAGCCCTGTGCACTGGTGAGAAGGGCTTCGGCTACAAAGGCTCCACCTTCCACAGGGTGATCCCTTCCTTCATGTGCCAGGCGGGCGACTTCACCAACCACAATGGCACAGGCGGGAAGTCCATCTACGGAAGCCGCTTTCCTGACGAGAACTTTACACTGAAGCACGTGGGGCCAGGTGTCCTGTCCATGGCTAATGCTGGTCCTAACACCAACGGCTCCCAGTTCTTCATCTGCACCATAAAGACAGACTGGTTGGATGGCAAGCATGTTGTGTTCGGTCACGTCAAAGAGGGCATGGACGTCGTGAAGAAAATAGAATCTTTCGGCTCTAAGAGTGGGAGGACATCCAAGAAGATTGTCATCACAGACTGTGGCCAGTTGAGCTAA
Protein sequence + ...

MLALRCGSRWLGLLSVPRSVPLRLPAARACSKGSGDPSSSSSSGNPLVYLDVDANGKPLGRVVLELKADVVPKTAENFRALCTGEKGFGYKGSTFHRVIPSFMCQAGDFTNHNGTGGKSIYGSRFPDENFTLKHVGPGVLSMANAGPNTNGSQFFICTIKTDWLDGKHVVFGHVKEGMDVVKKIESFGSKSGRTSKKIVITDCGQLS
GO Classification
process
physiological process
metabolism
macromolecule metabolism
protein metabolism
cellular protein metabolism
protein folding
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB00172 L-Proline
DB02078 1-Methoxy-2-[2-(2-Methoxy-Ethoxy]-Ethane
DB08168 7-AMINO-4-METHYL-CHROMEN-2-ONE

Associated as Prediction

Id Name
DB00091 Cyclosporine
DB00114 Pyridoxal Phosphate
DB00117 L-Histidine
DB00119 Pyruvic acid
DB00120 L-Phenylalanine
DB00123 L-Lysine
DB00125 L-Arginine
DB00126 Vitamin C
DB00128 L-Aspartic Acid
DB00130 L-Glutamine
DB00133 L-Serine
DB00134 L-Methionine
DB00135 L-Tyrosine
DB00138 L-Cystine
DB00139 Succinic acid
DB00142 L-Glutamic Acid
DB00145 Glycine
DB00149 L-Leucine
DB00150 L-Tryptophan
DB00151 L-Cysteine
DB00156 L-Threonine
DB00157 NADH
DB00160 L-Alanine
DB00161 L-Valine
DB00167 L-Isoleucine
DB00172 L-Proline
DB00174 L-Asparagine
DB00279 Liothyronine
DB00577 Valaciclovir
DB01235 Levodopa
DB01254 Dasatinib
DB01275 Hydralazine
DB01583 Liotrix
DB01610 Valganciclovir
DB01742 (3r)-1-Acetyl-3-Methylpiperidine
DB01746 D-Leucine
DB01786 D-Alanine
DB02078 1-Methoxy-2-[2-(2-Methoxy-Ethoxy]-Ethane
DB02419 Ethyl Oxo(Piperidin-1-Yl)Acetate
DB02510 '5'-O-(N-(L-Prolyl)-Sulfamoyl)Adenosine
DB02546 Vorinostat
DB02556 D-Phenylalanine
DB02565 4-Dimethylamino-N-(6-Hydroxycarbamoyethyl)Benzamide-N-Hydroxy-7-(4-Dimethyla Minobenzoyl)Aminoheptanamide
DB02580 1-(2-Methoxy-Ethoxy)-2-{2-[2-(2-Methoxy-Ethoxy]-Ethoxy}-Ethane
DB02684 5'-O-(N-(L-Cysteinyl)-Sulfamoyl)Adenosine
DB02917 N-Hydroxy-4-(Methyl{[5-(2-Pyridinyl)-2-Thienyl]Sulfonyl}Amino)Benzamide
DB02952 Alpha-Aminoisobutyric Acid
DB03107 Beta-Alanine
DB03225 D-Tryptophan
DB03376 '5'-O-(N-(L-Alanyl)-Sulfamoyl)Adenosine
DB03393 (3s,6s,9r,10r,11s,12s,13e,15e,18s,21s)-18-{(1e,3e,7s,8s)-9-[(2s,3r,4s,5s,6r,9s,11s)-9-Ethyl-4-Hydroxy-3,5,11-Trimethyl-8-Oxo-1-Oxa-7-Azaspiro[5.5]Undec-2-Yl]-8-Hydroxy-1,7-Dimethylnona-1,3-Dienyl}-10,12-Dihydroxy-3-(3-Hydroxybenzyl)-6-Isopropyl-11-Methyl-
DB03839 D-Tyrosine
DB03929 D-Serine
DB04297 7-[4-(Dimethylamino)Phenyl]-N-Hydroxy-4,6-Dimethyl-7-Oxo-2,4-Heptadienamide
DB04398 Lactic Acid
DB04447 1,4-Dithiothreitol
DB06262 Droxidopa
DB07350 (2E)-N-hydroxy-3-[1-methyl-4-(phenylacetyl)-1H-pyrrol-2-yl]prop-2-enamide
DB07586 5-(4-METHYL-BENZOYLAMINO)-BIPHENYL-3,4'-DICARBOXYLIC ACID 3-DIMETHYLAMIDE-4'-HYDROXYAMIDE
DB08168 7-AMINO-4-METHYL-CHROMEN-2-ONE
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