DT-Web

DB02684 - 5'-O-(N-(L-Cysteinyl)-Sulfamoyl)Adenosine


Identification
Name 5'-O-(N-(L-Cysteinyl)-Sulfamoyl)Adenosine
Accession Number DB02684 (EXPT00241)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 449.463
Groups experimental
Monoisotopic Weight 449.078737377
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase
Name Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase
Gene Name EPRS
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 1.0091

Predictions


Id Partner name Gene Name Score
4083 Peptidyl-prolyl cis-trans isomerase H PPIH 0.0154
4085 Peptidyl-prolyl cis-trans isomerase C PPIC 0.0154
4087 Pyrroline 5-carboxylate reductase isoform P5CR2 0.0154
4090 Chromosome 14 open reading frame 149 C14orf149 0.0154
4088 Probable prolyl-tRNA synthetase, mitochondrial PARS2 0.0154
4086 Peptidyl-prolyl cis-trans isomerase G PPIG 0.0154
4082 Proline oxidase, mitochondrial PRODH 0.0154
797 Sodium-dependent proline transporter SLC6A7 0.0154
4084 Peptidyl-prolyl cis-trans isomerase B PPIB 0.0146
2554 Peptidyl-prolyl cis-trans isomerase, mitochondrial PPIF 0.0137
248 Pyrroline-5-carboxylate reductase 1 PYCR1 0.013
802 Pyrroline-5-carboxylate reductase 2 PYCR2 0.013
4000 Prolyl 4-hydroxylase subunit alpha-2 P4HA2 0.0127
3874 Proline synthetase co-transcribed bacterial homolog protein PROSC 0.0124
471 Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) SLC6A14 0.0122
1524 Peptidyl-prolyl cis-trans isomerase A PPIA 0.012
6700 Peptidyl-prolyl cis-trans isomerase A ppiA 0.012
3949 Prolyl 3-hydroxylase 2 LEPREL1 0.0112
3945 Prolyl 3-hydroxylase 1 LEPRE1 0.0112
3951 Prolyl 3-hydroxylase 3 LEPREL2 0.0112
67 Prolyl 4-hydroxylase subunit alpha-1 P4HA1 0.0104
6151 Monocarboxylate transporter 10 SLC16A10 0.0101
4024 Mitochondrial glutamate carrier 2 SLC25A18 0.0048
4025 Mitochondrial glutamate carrier 1 SLC25A22 0.0048
4022 Glutamate--ammonia ligase domain-containing protein 1 LGSN 0.0048
4021 Probable glutamyl-tRNA synthetase, mitochondrial EARS2 0.0048
4016 Excitatory amino acid transporter 5 SLC1A7 0.0048
924 Glutamate receptor, ionotropic kainate 3 GRIK3 0.0048
4027 Glutamate receptor delta-1 subunit GRID1 0.0048
4026 Aspartyl aminopeptidase DNPEP 0.0048
915 Delta 1-pyrroline-5-carboxylate synthetase ALDH18A1 0.0048
4023 N-acetylglutamate synthase, mitochondrial NAGS 0.0048
1912 Excitatory amino acid transporter 1 SLC1A3 0.0048
4019 Excitatory amino acid transporter 4 SLC1A6 0.0048
1047 Excitatory amino acid transporter 2 SLC1A2 0.0048
664 Glutamate decarboxylase 2 GAD2 0.0048
3890 Glutamate decarboxylase 2 GAD2 0.0048
919 Glutamate receptor, ionotropic kainate 4 GRIK4 0.0048
4020 Glutamyl aminopeptidase ENPEP 0.0048
922 Glutamate receptor 4 GRIA4 0.0048
927 Metabotropic glutamate receptor 8 GRM8 0.0048
925 Metabotropic glutamate receptor 4 GRM4 0.0048
926 Metabotropic glutamate receptor 7 GRM7 0.0048
920 Glutamate receptor, ionotropic kainate 5 GRIK5 0.0048
4018 Glutamate receptor delta-2 subunit GRID2 0.0048
4017 5-oxoprolinase OPLAH 0.0048
625 Glutamate carboxypeptidase 2 FOLH1 0.0044
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.0042
3984 Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial PET112L 0.0041
917 Glutaminase kidney isoform, mitochondrial GLS 0.0041
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0041
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0041
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0041
5261 Phosphoribosylformylglycinamidine synthase purL 0.0041
5 Glutaminase liver isoform, mitochondrial GLS2 0.0041
3991 Glutamine-dependent NAD(+) synthetase NADSYN1 0.0041
668 Glutamate--cysteine ligase regulatory subunit GCLM 0.004
916 Metabotropic glutamate receptor 1 GRM1 0.0039
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0039
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0039
665 Phosphoserine aminotransferase PSAT1 0.0038
4652 Phosphoserine aminotransferase serC 0.0038
3895 Kynurenine--oxoglutarate transaminase 3 CCBL2 0.0038
801 Kynurenine/alpha-aminoadipate aminotransferase mitochondrial AADAT 0.0038
420 Glutamate decarboxylase 1 GAD1 0.0038
3900 Glutamate decarboxylase 1 GAD1 0.0038
923 Glutamate receptor 3 GRIA3 0.0038
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0037
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0036
1671 Excitatory amino acid transporter 3 SLC1A1 0.0036
426 Aspartate aminotransferase, mitochondrial GOT2 0.0036
914 Formimidoyltransferase-cyclodeaminase FTCD 0.0036
186 Glutamate--cysteine ligase catalytic subunit GCLC 0.0036
3877 Growth-inhibiting protein 18 GIG18 0.0035
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0035
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0034
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0034
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.0034
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0033
763 Tyrosine aminotransferase TAT 0.0033
5493 Tyrosine aminotransferase Not Available 0.0033
735 Alanine aminotransferase 1 GPT 0.0033
3904 Alanine aminotransferase 2 GPT2 0.0033
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0032
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0032
33 Cystine/glutamate transporter SLC7A11 0.0031
574 Branched-chain-amino-acid aminotransferase, cytosolic BCAT1 0.0031
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.003
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.003
3426 Glutamine synthetase glnA 0.003
3987 Glutamine synthetase GLUL 0.003
705 Glutamate receptor 1 GRIA1 0.003
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0029
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0028
738 Monocarboxylate transporter 1 SLC16A1 0.0026
921 Glutamate receptor 2 GRIA2 0.0023
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0023
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0023
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