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Calcium-binding mitochondrial carrier protein Aralar1


Partner ID 262
Name Calcium-binding mitochondrial carrier protein Aralar1
Synonyms 779
Gene name SLC25A12
General function Involved in amino acid transport activity
Specific function Calcium-dependent mitochondrial aspartate and glutamate carrier. May have a function in the urea cycle
Gene sequence + ...

ATGGCGGTCAAGGTGCAGACAACTAAGCGAGGGGATCCTCATGAGTTAAGAAACATATTTCTACAGTATGCCAGTACTGAGGTTGATGGAGAGCGTTACATGACCCCAGAAGACTTTGTTCAGCGCTATCTTGGACTGTATAATGATCCAAATAGTAACCCAAAGATCGTGCAGCTCTTGGCAGGAGTAGCTGATCAAACCAAGGATGGGTTGATCTCCTATCAAGAGTTTTTGGCATTTGAATCTGTTTTATGTGCTCCAGATTCCATGTTCATAGTGGCTTTCCAGTTGTTTGACAAGAGTGGAAATGGAGAGGTGACATTTGAAAATGTCAAAGAAATTTTTGGACAGACTATTATTCATCATCATATCCCTTTTAACTGGGATTGTGAATTTATCCGACTGCATTTTGGGCATAACCGGAAGAAGCATCTTAACTACACAGAATTCACGCAGTTTCTCCAGGAGCTGCAATTGGAACATGCAAGACAAGCCTTTGCACTCAAAGACAAAAGCAAAAGTGGCATGATTTCTGGTCTGGATTTCAGTGACATCATGGTTACCATTAGATCTCACATGCTTACTCCTTTTGTGGAGGAGAACTTAGTTTCAGCAGCTGGAGGAAGTATCTCACACCAGGTTAGCTTCTCCTACTTCAATGCATTTAACTCGTTACTGAATAACATGGAGCTTGTTCGTAAGATATATAGCACTCTAGCTGGCACAAGGAAAGATGTTGAAGTCACAAAGGAGGAATTTGCCCAGAGTGCCATACGCTATGGACAAGTCACACCACTAGAAATTGATATTCTATATCAGCTTGCAGACTTATATAATGCTTCAGGGCGCTTGACTTTGGCAGATATTGAGAGAATAGCCCCATTGGCTGAGGGGGCCTTACCTTACAACCTGGCAGAACTTCAGAGACAGCAGTCTCCTGGGTTAGGCAGGCCTATCTGGCTCCAGATTGCCGAGTCTGCTTACAGATTCACTCTGGGCTCAGTTGCTGGAGCTGTGGGAGCCACTGCAGTGTATCCTATAGATCTGGTGAAGACCCGAATGCAAAACCAGCGTGGCTCTGGCTCTGTTGTTGGGGAGCTAATGTACAAAAACAGCTTTGACTGTTTTAAGAAAGTCTTGCGTTATGAGGGCTTCTTTGGACTCTACAGGGGTCTGATACCACAACTTATAGGGGTTGCTCCAGAAAAGGCCATTAAACTGACTGTTAATGATTTTGTTCGGGACAAATTTACCAGAAGAGATGGCTCTGTTCCACTTCCAGCAGAAGTTCTTGCTGGAGGCTGTGCTGGAGGCTCTCAGGTCATTTTTACCAACCCATTGGAGATAGTGAAGATTCGTCTGCAAGTAGCTGGAGAGATCACCACGGGACCCAGAGTCAGCGCCCTGAATGTGCTCCGGGACTTGGGAATTTTTGGTCTGTATAAGGGTGCCAAAGCGTGTTTCCTCCGAGACATTCCCTTCTCTGCAATCTATTTTCCTGTTTATGCTCATTGCAAACTACTTCTGGCTGATGAAAATGGACACGTGGGAGGTTTAAATCTTCTTGCAGCTGGAGCCATGGCAGGTGTCCCAGCTGCATCTCTGGTGACCCCTGCTGATGTCATCAAGACAAGACTGCAGGTGGCTGCCCGCGCTGGCCAGACGACATACAGTGGTGTCATCGACTGTTTCAGGAAGATTCTCCGGGAAGAAGGGCCCTCAGCATTTTGGAAAGGGACTGCAGCTCGAGTGTTTCGATCCTCTCCCCAGTTTGGTGTTACCTTGGCTCATTATGAAGTTCTCCAGCGGTGGTTTTACATTGATTTTGGAGGCCTCAAACCCGCTGGTTCAGAACCAACACCTAAGTCACGCATTGCAGACCTTCCTCCTGCCAACCCTGATCACATCGGTGGATACAGACTCGCCACAGCCACGTTTGCAGGCATCGAAAACAAATTTGGCCTTTATCTCCCGAAATTTAAGTCTCCTAGTGTTGCTGTGGTTCAGCCAAAGGCAGCAGTGGCAGCCACTCAGTGA
Protein sequence + ...

MAVKVQTTKRGDPHELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFESVLCAPDSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQFLQELQLEHARQAFALKDKSKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGGSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQVTPLEIDILYQLADLYNASGRLTLADIERIAPLAEGALPYNLAELQRQQSPGLGRPIWLQIAESAYRFTLGSVAGAVGATAVYPIDLVKTRMQNQRGSGSVVGELMYKNSFDCFKKVLRYEGFFGLYRGLIPQLIGVAPEKAIKLTVNDFVRDKFTRRDGSVPLPAEVLAGGCAGGSQVIFTNPLEIVKIRLQVAGEITTGPRVSALNVLRDLGIFGLYKGAKACFLRDIPFSAIYFPVYAHCKLLLADENGHVGGLNLLAAGAMAGVPAASLVTPADVIKTRLQVAARAGQTTYSGVIDCFRKILREEGPSAFWKGTAARVFRSSPQFGVTLAHYEVLQRWFYIDFGGLKPAGSEPTPKSRIADLPPANPDHIGGYRLATATFAGIENKFGLYLPKFKSPSVAVVQPKAAVAATQ
GO Classification
component
membrane
organelle membrane
organelle inner membrane
mitochondrial inner membrane
cell
function
calcium ion binding
binding
ion binding
cation binding
transporter activity
process
physiological process
cellular physiological process
transport
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB00128 L-Aspartic Acid

Associated as Prediction

Id Name
DB00114 Pyridoxal Phosphate
DB00117 L-Histidine
DB00119 Pyruvic acid
DB00120 L-Phenylalanine
DB00123 L-Lysine
DB00125 L-Arginine
DB00128 L-Aspartic Acid
DB00130 L-Glutamine
DB00133 L-Serine
DB00134 L-Methionine
DB00135 L-Tyrosine
DB00138 L-Cystine
DB00139 Succinic acid
DB00142 L-Glutamic Acid
DB00145 Glycine
DB00149 L-Leucine
DB00150 L-Tryptophan
DB00151 L-Cysteine
DB00155 L-Citrulline
DB00156 L-Threonine
DB00160 L-Alanine
DB00161 L-Valine
DB00167 L-Isoleucine
DB00171 Adenosine triphosphate
DB00172 L-Proline
DB00174 L-Asparagine
DB00230 Pregabalin
DB00279 Liothyronine
DB00536 Guanidine
DB01235 Levodopa
DB01583 Liotrix
DB01746 D-Leucine
DB01786 D-Alanine
DB01812 Adenosine-3'-5'-Diphosphate
DB01842 3'-Phosphate-Adenosine-5'-Diphosphate
DB01942 Formic Acid
DB01961 Cytidine-3'-Monophosphate
DB02098 Adenosine-2'-5'-Diphosphate
DB02109 Hadacidin
DB02363 2'-Monophosphoadenosine-5'-Diphosphate
DB02556 D-Phenylalanine
DB02573 2'-Deoxycytidine-2'-Deoxyadenosine-3',5'-Monophosphate
DB02714 3'-Uridinemonophosphate
DB02783 4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate
DB02805 1-(3-O-Phosphono-Beta-L-Arabinofuranosyl)Pyrimidine-2,4(1h,3h)-Dione
DB02952 Alpha-Aminoisobutyric Acid
DB02987 Cysteine-S-Acetamide
DB03107 Beta-Alanine
DB03155 1-(2-Deoxy-2-Fluoro-3-O-Phosphono-Beta-L-Ribofuranosyl)Pyrimidine-2,4(1h,3h)-Dione
DB03186 U-Pi-a-Pi
DB03225 D-Tryptophan
DB03326 deoxycytidylyl-3',5'-guanosine
DB03431 Adenosine-5'-Diphosphate
DB03447 Uridylyl-2'-5'-Phospho-Adenosine
DB03448 2'-Deoxyuridine 3'-Monophosphate
DB03459 N-(Phosphonacetyl)-L-Aspartic Acid
DB03510 6-O-Phosphoryl Inosine Monophosphate
DB03512 Uridine-2',3'-Vanadate
DB03726 Purine Riboside-5'-Monophosphate
DB03765 Cytidine-2'-Monophosphate
DB03792 5-Amino-1h-Pyrimidine-2,4-Dione
DB03839 D-Tyrosine
DB03900 2-Methyl-2-Propanol
DB03929 D-Serine
DB04137 Guanosine-5'-Triphosphate
DB04272 Citric Acid
DB04299 Maleic Acid
DB04315 Guanosine-5'-Diphosphate
DB04398 Lactic Acid
DB04418 Adenylosuccinic Acid
DB04464 N-Formylmethionine
DB04514 Phosphoric Acid-2'-[2'-Deoxy-Uridine]Ester-5'-Guanosine Ester
DB04566 Inosinic Acid
DB06262 Droxidopa
DB08596 5'-deoxy-5'-piperidin-1-ylthymidine
DB08661 1-(2,5-dideoxy-5-pyrrolidin-1-yl-beta-L-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
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