DT-Web

DB02783 - 4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate


Identification
Name 4'-Deoxy-4'-Acetylyamino-Pyridoxal-5'-Phosphate
Accession Number DB02783 (EXPT01857)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 322.2085
Groups experimental
Monoisotopic Weight 322.056601978
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Aspartate aminotransferase, mitochondrial
Name Aspartate aminotransferase, mitochondrial
Gene Name GOT2
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.5127
4-aminobutyrate aminotransferase
Name 4-aminobutyrate aminotransferase
Gene Name gabT
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 0.7894

Predictions


Id Partner name Gene Name Score
2744 D-alanine aminotransferase dat 0.0979
2842 Glutamate-1-semialdehyde 2,1-aminomutase hemL 0.0852
2749 UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase arnB 0.0851
2249 Aspartate aminotransferase aspC 0.0851
2671 Aspartate aminotransferase aspC 0.0851
5490 Aspartate aminotransferase Not Available 0.0851
2546 Histidinol-phosphate aminotransferase hisC 0.0785
2698 Histidinol-phosphate aminotransferase hisC 0.0785
301 Kynurenine--oxoglutarate transaminase 1 CCBL1 0.0666
894 Alanine racemase alr 0.0645
2453 Alanine racemase alr 0.0645
795 Branched-chain-amino-acid aminotransferase, mitochondrial BCAT2 0.0619
3877 Growth-inhibiting protein 18 GIG18 0.0238
586 Aspartate aminotransferase, cytoplasmic GOT1 0.0211
1671 Excitatory amino acid transporter 3 SLC1A1 0.0181
2632 Adenylosuccinate synthetase purA 0.0175
3323 Adenylosuccinate synthetase purA 0.0175
3975 Adenylosuccinate synthetase ADSS 0.0175
4598 Adenylosuccinate synthetase Adss 0.0175
6817 Adenylosuccinate synthetase purA 0.0175
3972 Adenylosuccinate synthetase isozyme 2 ADSS 0.0175
533 Aminoacylase-1 ACY1 0.0175
3969 Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole- succinocarboxamide synthase PAICS 0.0175
799 Aspartyl-tRNA synthetase, cytoplasmic DARS 0.0175
513 Calcium-binding mitochondrial carrier protein Aralar2 SLC25A13 0.0175
305 Mitochondrial aspartate-glutamate carrier protein SLC25A13 0.0175
262 Calcium-binding mitochondrial carrier protein Aralar1 SLC25A12 0.0175
209 Aspartoacylase ASPA 0.0175
3979 Aspartoacylase-2 ACY3 0.0175
3976 Aspartyl-tRNA synthetase, mitochondrial DARS2 0.0175
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0158
585 Aspartyl/asparaginyl beta-hydroxylase ASPH 0.015
3977 ASRGL1 protein ASRGL1 0.0146
3971 CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase CAD 0.0139
740 Argininosuccinate synthase ASS1 0.012
865 Argininosuccinate synthase ASS1 0.012
2680 Argininosuccinate synthase argG 0.012
3194 Argininosuccinate synthase argG 0.012
3978 Adenylosuccinate synthetase isozyme 1 ADSSL1 0.0114
6151 Monocarboxylate transporter 10 SLC16A10 0.011
3895 Kynurenine--oxoglutarate transaminase 3 CCBL2 0.0103
665 Phosphoserine aminotransferase PSAT1 0.0103
4652 Phosphoserine aminotransferase serC 0.0103
801 Kynurenine/alpha-aminoadipate aminotransferase mitochondrial AADAT 0.0103
420 Glutamate decarboxylase 1 GAD1 0.0103
3900 Glutamate decarboxylase 1 GAD1 0.0103
5682 Ribonuclease pancreatic RNASE1 0.0087
914 Formimidoyltransferase-cyclodeaminase FTCD 0.0086
763 Tyrosine aminotransferase TAT 0.0086
5493 Tyrosine aminotransferase Not Available 0.0086
735 Alanine aminotransferase 1 GPT 0.0085
3904 Alanine aminotransferase 2 GPT2 0.0085
574 Branched-chain-amino-acid aminotransferase, cytosolic BCAT1 0.0076
280 4-aminobutyrate aminotransferase, mitochondrial ABAT 0.0072
4025 Mitochondrial glutamate carrier 1 SLC25A22 0.0059
4023 N-acetylglutamate synthase, mitochondrial NAGS 0.0059
4022 Glutamate--ammonia ligase domain-containing protein 1 LGSN 0.0059
4021 Probable glutamyl-tRNA synthetase, mitochondrial EARS2 0.0059
1912 Excitatory amino acid transporter 1 SLC1A3 0.0059
4024 Mitochondrial glutamate carrier 2 SLC25A18 0.0059
4016 Excitatory amino acid transporter 5 SLC1A7 0.0059
4019 Excitatory amino acid transporter 4 SLC1A6 0.0059
1047 Excitatory amino acid transporter 2 SLC1A2 0.0059
664 Glutamate decarboxylase 2 GAD2 0.0059
3890 Glutamate decarboxylase 2 GAD2 0.0059
926 Metabotropic glutamate receptor 7 GRM7 0.0059
4027 Glutamate receptor delta-1 subunit GRID1 0.0059
915 Delta 1-pyrroline-5-carboxylate synthetase ALDH18A1 0.0059
4026 Aspartyl aminopeptidase DNPEP 0.0059
922 Glutamate receptor 4 GRIA4 0.0059
927 Metabotropic glutamate receptor 8 GRM8 0.0059
925 Metabotropic glutamate receptor 4 GRM4 0.0059
924 Glutamate receptor, ionotropic kainate 3 GRIK3 0.0059
919 Glutamate receptor, ionotropic kainate 4 GRIK4 0.0059
4020 Glutamyl aminopeptidase ENPEP 0.0059
920 Glutamate receptor, ionotropic kainate 5 GRIK5 0.0059
4018 Glutamate receptor delta-2 subunit GRID2 0.0059
4017 5-oxoprolinase OPLAH 0.0059
3911 Uncharacterized protein C20orf38 SPTLC3 0.0059
3906 Serine dehydratase-like SDSL 0.0059
3881 Selenocysteine lyase variant Not Available 0.0059
3887 Phosphorylase PYGB 0.0059
3908 P-selectin cytoplasmic tail-associated protein pcap 0.0059
3915 Cysteine sulfinic acid decarboxylase-related protein 1 CSAD 0.0059
3914 Alanine-glyoxylate aminotransferase homolog TLH6 0.0059
306 Pyridoxal phosphate phosphatase PDXP 0.0059
3886 Migration-inducing protein 4 ALAS1 0.0059
3896 CDNA FLJ46802 fis, clone TRACH3032150, moderately similar to Cysteine sulfinic acid decarboxylase GADL1 0.0059
3909 Hepatic peroxysomal alanine:glyoxylate aminotransferase Not Available 0.0059
3878 GAD1 protein GAD1 0.0059
3893 DDC protein DDC 0.0059
3880 Serine hydroxymethyltransferase 1 Not Available 0.0059
3883 Ornithine aminotransferase variant Not Available 0.0059
3910 O-phosphoseryl-tRNA(Sec) selenium transferase SEPSECS 0.0059
855 Sphingosine-1-phosphate lyase 1 SGPL1 0.0059
3903 Aminolevulinate, delta-, synthase 2 ALAS2 0.0059
3891 Putative L-Dopa decarboxylase DDC 0.0059
3894 KIAA0251 protein PDXDC1 0.0059
3875 Glycogen phosphorylase, brain form PYGB 0.0059
3882 Brain glycogen phosphorylase variant Not Available 0.0059
3905 Molybdenum cofactor sulfurase MOCOS 0.0059
668 Glutamate--cysteine ligase regulatory subunit GCLM 0.005
3899 Alanine--glyoxylate aminotransferase 2-like 2 AGXT2L2 0.005
830 Glutamate dehydrogenase 2, mitochondrial GLUD2 0.005
491 Serine palmitoyltransferase 1 SPTLC1 0.005
431 Serine racemase SRR 0.005
89 Cysteine sulfinic acid decarboxylase CSAD 0.005
727 Serine palmitoyltransferase 2 SPTLC2 0.005
184 L-serine dehydratase SDS 0.005
534 Threonine synthase-like 1 THNSL1 0.005
3984 Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial PET112L 0.005
917 Glutaminase kidney isoform, mitochondrial GLS 0.005
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.005
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.005
3991 Glutamine-dependent NAD(+) synthetase NADSYN1 0.005
5 Glutaminase liver isoform, mitochondrial GLS2 0.005
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.005
5261 Phosphoribosylformylglycinamidine synthase purL 0.005
3874 Proline synthetase co-transcribed bacterial homolog protein PROSC 0.0049
3 Histidine decarboxylase HDC 0.0049
625 Glutamate carboxypeptidase 2 FOLH1 0.0049
499 Arginine decarboxylase ADC 0.0049
455 5-aminolevulinate synthase, nonspecific, mitochondrial ALAS1 0.0048
575 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial GCAT 0.0048
681 Glycine dehydrogenase [decarboxylating], mitochondrial GLDC 0.0048
3913 Glutamic acid decarboxylase GAD65 0.0047
435 Kynureninase KYNU 0.0046
4654 Kynureninase kynU 0.0046
382 Glutamate receptor, ionotropic kainate 1 GRIK1 0.0046
169 Cysteine desulfurase, mitochondrial NFS1 0.0046
916 Metabotropic glutamate receptor 1 GRM1 0.0045
186 Glutamate--cysteine ligase catalytic subunit GCLC 0.0044
472 Ornithine aminotransferase, mitochondrial OAT 0.0044
203 Pyridoxine-5'-phosphate oxidase PNPO 0.0043
358 Cystathionine beta-synthase CBS 0.0043
923 Glutamate receptor 3 GRIA3 0.0043
3884 SHMT2 protein SHMT2 0.0043
3901 SHMT2 protein SHMT2 0.0043
3885 Hypothetical protein DKFZp686P09201 DKFZp686P09201 0.0043
3879 Serine hydroxymethyltransferase 2 Not Available 0.0043
321 Serine hydroxymethyltransferase, mitochondrial SHMT2 0.0043
201 Glutamate dehydrogenase 1, mitochondrial GLUD1 0.0043
448 Vitamin K-dependent gamma-carboxylase GGCX 0.0043
868 Cystathionine gamma-lyase CTH 0.0042
83 Alpha-aminoadipic semialdehyde synthase, mitochondrial AASS 0.0042
773 Folylpolyglutamate synthase, mitochondrial FPGS 0.0042
114 Alanine--glyoxylate aminotransferase 2, mitochondrial AGXT2 0.0041
210 Bifunctional aminoacyl-tRNA synthetase [Includes: Glutamyl-tRNA synthetase EPRS 0.0041
505 Glutamate [NMDA] receptor subunit epsilon-3 GRIN2C 0.0039
349 Serine--pyruvate aminotransferase AGXT 0.0039
439 Glutamate [NMDA] receptor subunit epsilon-4 GRIN2D 0.0039
367 Serine hydroxymethyltransferase, cytosolic SHMT1 0.0038
449 Ornithine decarboxylase ODC1 0.0038
401 Glutamate [NMDA] receptor subunit zeta-1 GRIN1 0.0037
591 Glutamate [NMDA] receptor subunit 3B GRIN3B 0.0037
705 Glutamate receptor 1 GRIA1 0.0036
33 Cystine/glutamate transporter SLC7A11 0.0036
3426 Glutamine synthetase glnA 0.0035
3987 Glutamine synthetase GLUL 0.0035
464 Glutamate [NMDA] receptor subunit epsilon-2 GRIN2B 0.0035
3876 Aromatic-L-amino-acid decarboxylase DDC 0.0034
837 Glutamate [NMDA] receptor subunit epsilon-1 GRIN2A 0.0034
10 Glycogen phosphorylase, liver form PYGL 0.0033
738 Monocarboxylate transporter 1 SLC16A1 0.0029
706 Glutamate [NMDA] receptor subunit 3A GRIN3A 0.0028
918 Glutamate receptor, ionotropic kainate 2 GRIK2 0.0027
921 Glutamate receptor 2 GRIA2 0.0026
1152 Glycogen phosphorylase, muscle form PYGM 0.0025
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