DT-Web

DB03459 - N-(Phosphonacetyl)-L-Aspartic Acid


Identification
Name N-(Phosphonacetyl)-L-Aspartic Acid
Accession Number DB03459 (EXPT02494)
Type small molecule
Description Not Available
Structure
MOL SDF PDB SMILES InChI
Categories (*)
Molecular Weight 255.1193
Groups experimental
Monoisotopic Weight 255.014402813
Pharmacology
Indication Not Available
Mechanism of action Not Available
Absorption Not Available
Protein binding Not Available
Biotransformation Not Available
Route of elimination Not Available
Toxicity Not Available
Affected organisms Not Available
Interactions
Drug Interactions Not Available
Food Interactions Not Available

Targets


Aspartate carbamoyltransferase catalytic chain
Name Aspartate carbamoyltransferase catalytic chain
Gene Name pyrB
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
DTHybrid score 1.2939
CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase
Name CAD protein [Includes: Glutamine-dependent carbamoyl-phosphate synthase
Gene Name CAD
Pharmacological action unknown
Actions Not Available
References
  • Overington JP, Al-Lazikani B, Hopkins AL: How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6. - Pubmed
  • Imming P, Sinning C, Meyer A: Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov. 2006 Oct;5(10):821-34. - Pubmed
  • Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, Bourne PE: The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. - Pubmed
DTHybrid score 0.9002

Predictions


Id Partner name Gene Name Score
242 Asparagine synthetase [glutamine-hydrolyzing] ASNS 0.0309
2632 Adenylosuccinate synthetase purA 0.0251
3323 Adenylosuccinate synthetase purA 0.0251
3975 Adenylosuccinate synthetase ADSS 0.0251
4598 Adenylosuccinate synthetase Adss 0.0251
6817 Adenylosuccinate synthetase purA 0.0251
3979 Aspartoacylase-2 ACY3 0.0251
3976 Aspartyl-tRNA synthetase, mitochondrial DARS2 0.0251
3972 Adenylosuccinate synthetase isozyme 2 ADSS 0.0251
209 Aspartoacylase ASPA 0.0251
799 Aspartyl-tRNA synthetase, cytoplasmic DARS 0.0251
533 Aminoacylase-1 ACY1 0.0251
3969 Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole- succinocarboxamide synthase PAICS 0.0251
513 Calcium-binding mitochondrial carrier protein Aralar2 SLC25A13 0.0251
305 Mitochondrial aspartate-glutamate carrier protein SLC25A13 0.0251
262 Calcium-binding mitochondrial carrier protein Aralar1 SLC25A12 0.0251
3992 Protein-glutamine gamma-glutamyltransferase Z TGM7 0.0222
3990 Protein-glutamine gamma-glutamyltransferase 4 TGM4 0.0222
3986 Protein-glutamine gamma-glutamyltransferase 6 TGM6 0.0222
3983 Protein-glutamine gamma-glutamyltransferase 5 TGM5 0.0222
3989 Glutaminyl-tRNA synthetase QARS 0.0222
3988 Protein-glutamine gamma-glutamyltransferase K TGM1 0.0222
1008 CTP synthase 1 CTPS 0.0222
3985 Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 2 GFPT2 0.0222
585 Aspartyl/asparaginyl beta-hydroxylase ASPH 0.0213
6151 Monocarboxylate transporter 10 SLC16A10 0.0213
3977 ASRGL1 protein ASRGL1 0.0205
917 Glutaminase kidney isoform, mitochondrial GLS 0.0185
355 GMP synthase [glutamine-hydrolyzing] GMPS 0.0185
4353 GMP synthase [glutamine-hydrolyzing] guaA 0.0185
3991 Glutamine-dependent NAD(+) synthetase NADSYN1 0.0185
5 Glutaminase liver isoform, mitochondrial GLS2 0.0185
3984 Probable glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial PET112L 0.0185
3982 Phosphoribosylformylglycinamidine synthase PFAS 0.0185
5261 Phosphoribosylformylglycinamidine synthase purL 0.0185
263 Neutral amino acid transporter B(0) SLC1A5 0.0185
1596 Protein-glutamine gamma-glutamyltransferase 2 TGM2 0.0182
1671 Excitatory amino acid transporter 3 SLC1A1 0.0181
6 Coagulation factor XIII A chain F13A1 0.0175
3877 Growth-inhibiting protein 18 GIG18 0.0174
413 Amidophosphoribosyltransferase PPAT 0.0166
2515 Amidophosphoribosyltransferase purF 0.0166
3714 Amidophosphoribosyltransferase purF 0.0166
314 System N amino acid transporter 1 SLC38A3 0.0165
426 Aspartate aminotransferase, mitochondrial GOT2 0.0165
740 Argininosuccinate synthase ASS1 0.0162
865 Argininosuccinate synthase ASS1 0.0162
2680 Argininosuccinate synthase argG 0.0162
3194 Argininosuccinate synthase argG 0.0162
586 Aspartate aminotransferase, cytoplasmic GOT1 0.016
3978 Adenylosuccinate synthetase isozyme 1 ADSSL1 0.0152
866 Large neutral amino acids transporter small subunit 2 SLC7A8 0.0152
2339 Protein-glutamine gamma-glutamyltransferase E TGM3 0.0147
301 Kynurenine--oxoglutarate transaminase 1 CCBL1 0.0143
3426 Glutamine synthetase glnA 0.0125
3987 Glutamine synthetase GLUL 0.0125
5682 Ribonuclease pancreatic RNASE1 0.0113
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