DT-Web

Phenylalanyl-tRNA synthetase beta chain


Partner ID 6603
Name Phenylalanyl-tRNA synthetase beta chain
Synonyms 104
Gene name pheT
General function Translation, ribosomal structure and biogenesis
Specific function ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe)
Gene sequence + ...

ATGTCAGAACAAGAAATTTGGAAAAAAGTATTAGAAGTTGCTGAATCAGAAATATCTAAATCGACATTTAATACTTTTTTGAAAGATACAGAACTCAAAGAAATTCGTGATAATGTTGCAATCATCTTTGTAATTCATGAATTTTACGCAGAATGGTTAAATTCAAACTACAAAGAAGTAATCCAAACAATTATGAAAGATGTTATTGGTTATGAAGTTGAACCCAAATTTTTCACTGCTGAACAATTAGCTGAACTTGATGAGACAAGTCGTAAATCTAACACGCCAAGCGAACCTCAACGTCAAATCATTGAATATGGTCATGAAGGCACAGATCAATTCAATACTCACAATACATTTGATACTTTCGTCATTGGACCTGGCAATAGATTTCCACACGCAGCAAGTCTTGCAGTTGCTGAAGCACCAGCACAAGCATACAACCCTCTATTTATATATGGTGGCGTTGGTCTTGGTAAGACACATCTTATGCATGCGATCGGTCATCATGTTCTTAGCAATCAACCAAATGCTAAAGTACTATATACTTCAAGTGAAAAATTCACAAATGACTTCATCAAATCAATTCGTAACAATGAACCTGAAGCCTTTAGAGAAAAGTATAGAAACATCGACGTGTTACTGATTGATGACATTCAATTTATTCAGAATAAAGAACAAACGCAAGAAGAGTTCTTCCATACATTTAATGAATTACATCAAAATAAGAAGCAAATTGTCATTTCAAGTGACCGTCCACCTAAAGAAATTGCAAAATTAGAAGACCGTTTACGTTCTCGTTTCGAATGGGGATTAATCGTTGATATTACTCCTCCTGACTATGAAACACGTATGGCGATTCTTCAGAAAAAAATCGAAGAAGAGAATTTAGAAATTCCTGCTGAAGCTTTAAATTATATTGCTAATCAAATTCAATCAAACATCCGTGAATTAGAAGGCGCACTCACACGTTTGCTTGCCTATTCTAAACTTCAAGGCAGACCTATTACGACTGAATTAGCGGCAGAAGCGCTCAAAGATATTATTCAAGTTCCTAAATCTAAAAAAATTACAATCCAAGATATTCAAAAAGTCGTTGGACACTACTACAACGTTCGCATCGAAGATTTCAGCGCAAAAAAACGTACAAAATCAATTGCTTATCCACGTCAAATTGCGATGTATTTATCAAGAGAACTTACCGATTTTTCATTACCTAAGATTGGTGAAGAATTCGGTGGTCGAGATCATACGACAGTGATTCATGCGCACGAAAAGATTGCTAAAGATATTAAAGCCGATACAATTTTTAAACAAGAAGTTGAAGATTTGGAAAAAGAAATTCGCAATCAATAA
Protein sequence + ...

MLISNEWLKDYVDAGVKVEDLAERITRTGIEVDDMIDYSKDIKNLVVGYIQSKEKHPDADKLNICQVDIGEEEPVQIVCGAPNVDAGQHVIVAKVGGRLPGGIKIKRAKLRGERSEGMICSLQEIGISSNVVPKAYENGIFVFQTEVEPGTDALTALYLNDQVMEFDLTPNRADALSMVGTAYEVAALYQTEMTKPETQSNETSESATNELSVTIDNPEKVPYYSARVVKNVSIEPSPIWVQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQDHIGSKEIVVRQAKDEETMTTLDNNERKLVDTDIVISNGQEPIALAGVMGGDFSEVTEQTTNVVIEGAIFDPVSIRHTSRRLNLRSEASSRFEKGIATEFVDEAVDRACYLLQELASGEVLQDRVSSGDLGSFVTPIDITAEKVNKTIGFNLSNDEIQSIFRQLGFETTLKGETLTVNVPSRRKDITIKEDLIEEVARIYGYDEIPSSLPVFGEVTSGELTDRQHKTRTLKETLEGAGLNQAITYSLVSKDHAKDFALQERPTISLLMPMSEAHATLRQSLLPHLIEATAYNVARKNKDVRLYEIGRVFFGNGEGELPDEVEYLSGILTGEYVVNAWQGKKEEIDFFIAKGVVDRVAEKLNLEFSYKAGKIEGLHPGRTAIVSLEGQDIGFIGELHPQVAADNDLKRTYVFELNYDAMMQVAVGYINYEQIPKFPGVTRDIALEVNHDVPSSELKQIIHNNGEDILQSTLVFDVYEGEHLEKGKKSVAIRLNYLDTEDTLTDERVSKIHDKILEALQAQGATIR
GO Classification
component
intracellular
cytoplasm
cell
function
ATP binding
nucleic acid binding
tRNA binding
binding
RNA binding
nucleotide binding
ligase activity
catalytic activity
ligase activity, forming phosphoric ester bonds
RNA ligase activity
tRNA ligase activity
purine nucleotide binding
phenylalanine-tRNA ligase activity
adenyl nucleotide binding
process
tRNA aminoacylation
tRNA aminoacylation for protein translation
phenylalanyl-tRNA aminoacylation
physiological process
nucleobase, nucleoside, nucleotide and nucleic acid metabolism
metabolism
cellular metabolism
RNA metabolism
tRNA metabolism
See more information at   →   www.drugbank.ca

Drugs


Associated as Target

Id Name
DB07817 1-{3-[(4-pyridin-2-ylpiperazin-1-yl)sulfonyl]phenyl}-3-(1,3-thiazol-2-yl)urea

Associated as Prediction

Id Name
DB00114 Pyridoxal Phosphate
DB00117 L-Histidine
DB00119 Pyruvic acid
DB00120 L-Phenylalanine
DB00123 L-Lysine
DB00125 L-Arginine
DB00128 L-Aspartic Acid
DB00130 L-Glutamine
DB00133 L-Serine
DB00134 L-Methionine
DB00135 L-Tyrosine
DB00138 L-Cystine
DB00142 L-Glutamic Acid
DB00145 Glycine
DB00149 L-Leucine
DB00150 L-Tryptophan
DB00151 L-Cysteine
DB00156 L-Threonine
DB00160 L-Alanine
DB00161 L-Valine
DB00167 L-Isoleucine
DB00172 L-Proline
DB00174 L-Asparagine
DB00279 Liothyronine
DB00360 Tetrahydrobiopterin
DB00368 Norepinephrine
DB00668 Epinephrine
DB00765 Metyrosine
DB01235 Levodopa
DB01583 Liotrix
DB01746 D-Leucine
DB01786 D-Alanine
DB02556 D-Phenylalanine
DB02562 Quinonoid 7,8-Tetrahydrobiopterin
DB02692 (6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin
DB02750 S-(Methylmercury)-L-Cysteine
DB02952 Alpha-Aminoisobutyric Acid
DB03107 Beta-Alanine
DB03225 D-Tryptophan
DB03552 Meta-Tyrosine
DB03673 Beta(2-Thienyl)Alanine
DB03839 D-Tyrosine
DB03929 D-Serine
DB04398 Lactic Acid
DB04400 7,8-Dihydrobiopterin
DB04419 Norleucine
DB06262 Droxidopa
DB07817 1-{3-[(4-pyridin-2-ylpiperazin-1-yl)sulfonyl]phenyl}-3-(1,3-thiazol-2-yl)urea
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