| Name |
Protein-L-isoaspartate O-methyltransferase |
| Synonyms |
3719 |
| Gene name |
pcm |
| General function |
Involved in RNA binding |
| Specific function |
Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins |
| Gene sequence |
+ ...
TCAAATAGAACAGGATATATGTGAAAAAGCGTTGTAACCCACATGAAGCATGAGATACTCGAAGCTCCTGTAGCCGCAGCTTTCCCACTGAGTTAAAAGGTTCTCTATCTCTGGAGCGTCCCCGTAGATTCTCATCCTGTCATCGAGAAACTCTACCACGCCGTTTGGCCCAGCGTAGTAGAACGTTCCATCAATCTCTGTGAGTCTCCTGGTGAGGAGATCCACCAGCTCCACGAAGATATGAGAACGTACGAGTAAGATCTCTCTGTTGAATGGAAATTCTCTCAAAAGCTTTCTGTTCCTCTCGAGAAGATTTCCGAGATTGCCCCCTGCCGTTATGAACCTGGTTTCCAGTTTGTAGTTTCCCACAAGATACGGATCCTTTTTTTTGAACAGGAAAGCGGGCTGTCTTCTTGAAAGTTTCAAATTGATAGGTACTATCACCCTCCCACCTTCTTTGAGTTGAGTGAACCACGTCTCCGGCACCTCATCCACACCGACTGTTACGAAGATAACATCGTACGGGGAAAACTCCGGAACACCGTAGTATCCATCGCCACAGACAAAAATAACGTTCTCTATTCCAAGGCGTTCCACGTTCCTTTTCGCGATCTCGCAGATTTTCCTCGAATATTCCACGGAGACCACAAGGCCTTTCTCACCCACAACTCTGCTCATCACGGCAGCGTTGTAACCCGTTCCTCCGCCTATTTCGAGGACTCTCATTCCTTTGTCCAGACCCACCCACTCCATAAACAGCGCCATCAAAGAGGGCTGACTGGAAGTGCTGTATTCTTCTCCATCATCGTAGGAAACCAGAACGATATCCTCGTAAACGTAAGAGAGTGGGTAGGACTTCGTCAGGAACTCCTCACGGGGTATTTCCAGAAAAGCCTTCGCGATGTGATCGCTCACACCGTACTTTTTAAGAATCCAAAAGAGCTTTTCTCTCAT
|
| Protein sequence |
+ ...
MREKLFWILKKYGVSDHIAKAFLEIPREEFLTKSYPLSYVYEDIVLVSYDDGEEYSTSSQPSLMALFMEWVGLDKGMRVLEIGGGTGYNAAVMSRVVGEKGLVVSVEYSRKICEIAKRNVERLGIENVIFVCGDGYYGVPEFSPYDVIFVTVGVDEVPETWFTQLKEGGRVIVPINLKLSRRQPAFLFKKKDPYLVGNYKLETRFITAGGNLGNLLERNRKLLREFPFNREILLVRSHIFVELVDLLTRRLTEIDGTFYYAGPNGVVEFLDDRMRIYGDAPEIENLLTQWESCGYRSFEYLMLHVGYNAFSHISCSI
|
| GO Classification |
| component |
| organelle |
| membrane-bound organelle |
| intracellular membrane-bound organelle |
| nucleus |
| function |
| O-methyltransferase activity |
| protein-L-isoaspartate (D-aspartate) O-methyltransferase activity |
| transferase activity |
| transferase activity, transferring one-carbon groups |
| methyltransferase activity |
| binding |
| catalytic activity |
| nucleic acid binding |
| RNA binding |
| process |
| protein modification |
| RNA processing |
| rRNA processing |
| physiological process |
| metabolism |
| cellular metabolism |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolism |
| macromolecule metabolism |
| RNA metabolism |
| biopolymer metabolism |
| biopolymer modification |
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